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Type D4700NANOpure Bioresearch

Deionization SystemOPERATION MANUAL

AND PARTS LISTSERIES 747

BIORESEARCH GRADE SYSTEMS

Model # Voltage MountD4751D4752D4753D4754D4755D4756

120240100120240100

WallWallWall

BenchBenchBench

LT747X2 • 9/22/97 Serial Number

BARNSTEAD|THERMOLYNE CORPORATION

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This manual contains important operating and safety information. You must carefullyread and understand the contents of this manual prior to the use of this equipment.

Control Panel

Water Inlet

RemoteDispenser

UltrafilterFlush Valve

Canisters

ultrapure water systemNANOpure

UltrafilteredWaterDrawoffValve

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Table of Contents

Safety Information .............................................................................................................................................. 4Alert Boxes ......................................................................................................................................................... 4Warnings ............................................................................................................................................................ 4Introduction ........................................................................................................................................................ 6Introduction ........................................................................................................................................................ 6Technical Specifications - Bioresearch Grade ................................................................................................... 7Installation .......................................................................................................................................................... 8

Unpacking .................................................................................................................................................... 9Choosing a Site ........................................................................................................................................... 9Tubing Connector Installation .................................................................................................................... 10Mounting and Utility Connections .............................................................................................................. 11Initial Sanitization and Ultrafilter Installation .............................................................................................. 13

Initial Operation ................................................................................................................................................ 18Initial Operation ......................................................................................................................................... 18

Normal Operation ............................................................................................................................................. 22Smart Purity Meter ........................................................................................................................................... 23Modes of Operation.......................................................................................................................................... 23Turning Unit On or Off ...................................................................................................................................... 23Selecting the Set Point ..................................................................................................................................... 24Displaying the Temperature ............................................................................................................................. 25Checking the Calibration .................................................................................................................................. 25Inlet Cell ........................................................................................................................................................... 26Installation ........................................................................................................................................................ 26Inlet Cell Operation .......................................................................................................................................... 27Remote Display Mounting ................................................................................................................................ 28Remote Dispenser ........................................................................................................................................... 30Installing Float or Pressure Switch ................................................................................................................... 31Maintenance and Servicing .............................................................................................................................. 33Replacing Cartridges........................................................................................................................................ 33Replacing the Remote Dispenser 0.2 Micron Final Filter ................................................................................. 33Replacing the Ultrafiltered Water Drawoff 0.2 Micron Final Filter .................................................................... 34Replacing Fuses .............................................................................................................................................. 35

Main Fuse Replacement ............................................................................................................................ 35Printed Circuit Fuse Replacement ............................................................................................................. 36

System Sanitization.......................................................................................................................................... 36Cleaning the Resistivity Cell ............................................................................................................................. 38Shutdown ......................................................................................................................................................... 39Stopping the Constant Bleed ........................................................................................................................... 40Troubleshooting Guide ..................................................................................................................................... 41Replacement Parts Listing ............................................................................................................................... 44Recommended Spares .................................................................................................................................... 44

Consumables ............................................................................................................................................. 44General Maintenance Parts ....................................................................................................................... 45

Ordering Procedures ........................................................................................................................................ 46Exploded View ................................................................................................................................................. 47Wiring Diagrams............................................................................................................................................... 49One Year Limited Warranty.............................................................................................................................. 52

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Warnings

To avoid electrical shock, always:1. Use with a properly grounded electrical

outlet of correct voltage and currenthandling capacity.

2. Do not mount the NANOpure Bioresearchdirectly over equipment that requireselectrical service. Routine maintenance ofthis unit may involve water spillage andsubsequent electrical shock hazard ifimproperly located.

3. Replace fuses with those of the same typeand rating.

4. Disconnect from the power supply prior tomaintenance and servicing.

To avoid personal injury:

1. Do not use in the presence of flammableor combustible materials; fire or explosionmay result. This device containscomponents which may ignite suchmaterials.

2. This device is to be used with water feedsonly. Sanitizing/cleaning agents must beused in compliance with instructions in thismanual. Failure to comply with the abovecould result in explosion and personalinjury.

3. Do not mount the NANOpure Bioresearchdirectly over equipment that requireselectrical service. Routine maintenance ofthis unit may involve water spillage andsubsequent electrical shock hazard ifimproperly located.

Safety Information

WarningWarnings alert you to apossibility of personal injury.

CautionCautions alert you to apossibility of damage to theequipment.

NoteNotes alert you to pertinentfacts and conditions.

Alert Signals

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4. Replace fuses only with the same typeand rating for continued protection againstpossible fire hazard.

5. Wall composition and construction, as wellas fastener type, must be consideredwhen mounting this unit. The mountingsurface and fasteners selected must becapable of supporting a minimum of 275lbs. Inadequate support and/or fastenersmay result in damage to mounting surfaceand/or equipment. If you are unsure ofmounting surface composition, conditionand construction, or correct fasteners,consult your building maintenance groupor contractor.

6. Avoid splashing disinfecting solutions onclothing or skin. Ensure all pipingconnections are tight to avoid chemicalleakage. Always depressurize chemicallines before disassembly. Ensureadequate ventilation. Carefully followmanufacturer’s safety instructions onlabels of chemical containers and materialsafety data sheets.

7. A small amount of 2.0% hydrogenperoxide is used to preserve the ultrafilterduring storage. When removing theultrafilter from the bag, ensure adequateventilation and wear protective gloves andglasses.

8. Depressurize system prior to attempting toremove canisters.

9. Refer servicing to qualified personnel.

SAFETY INFORMATION

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Introduction

This manual contains the information you willneed to install, operate, and maintain theNANOpure Bioresearch Grade, Series 747,ultrapure water system manufactured byBarnstead|Thermolyne Corporation. It is yourresponsibility to read and understand the contentsof this manual prior to installation and use of thisequipment.

The NANOpure Bioresearch is designed toproduce Type I Reagent Grade Water equal to orexceeding standards established by ASTM, CAP,and NCCLS with bacterial endotoxin levels below0.005 EU/ml. Careful attention to the followinginstructions will assure that the NANOpureBioresearch runs properly and produces water tospecification. Illustrated parts lists are attachedinside. Take a few minutes to familiarize yourselfwith the hardware before installation.

The unit includes a constant bleed of theultrafiltered reject water. This bleed can bediscontinued if you feel it is not required. See theappropriate section of this manual if you want tostop the constant bleed.

Introduction

Figure A NANOpure Bioresearch Water Pathway Diagram.

WarningThis device is to be usedwith water feeds only.Sanitizing/cleaning agentsmust be used in compliancewith instructions in thismanual. Failure to complywith the above could result inexplosion and personalinjury.

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Technical Specifications -Bioresearch Grade

Feed Water RequirementsTypes

1Tap (Potable), RO, DI, Distilled.

Pressure Range Gravity feed to 100 psig (7 kg/cm2) maximum.

Temperature Range 4-49°C (40-120°F)Product Water

Water Quality1

Remote Dispenser and Ultrafiltered Water Drawoff -Type I Reagent Grade Water (RGW) per ASTM-D1193, NCCLS ASC-3, and CAP.Flow rate (Maximum)

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From Dispenser From Ultrafiltered Water Drawoff.Pressured Feed(40 psig Inlet Min.) 50 HZ 1.5 LPM 1.25 LPM

60 Hz 1.6 LPM 1.3 LPMGravity Feed(12" Minimum) 50 Hz 1.0 LPM 1.0 LPM

60 Hz 1.1 LPM 1.1 LPM

DimensionsWall mounted models

Width 22" (559 mm)Depth 14 1/4" (362 mm)Height 29 1/2" (749 mm)

Bench mounted modelsWidth 22" (559 mm)Depth 16 1/4" (413 mm)Height 32 1/2" (826 mm)

Plumbing ConnectionsFeed water Inlet 3/8" OD tubing or 1/4" NPTFUltrafilter Reject 3/8" hose-barb

Electrical Requirements (depending on model supplied)Voltage and Frequency (Nominal)

100 VAC, 50/60 Hz 85-110 VAC, 47-63 Hz, 1 phase115 VAC, 50/60 Hz 98-127 VAC, 47-63 Hz, 1 phase230 VAC, 50/60 Hz 196-253 VAC, 47-63 Hz, 1 phase

Protection100 VAC service 3 ampere slow blow fuse115 VAC service 3 ampere slow blow fuse230 VAC service 2 ampere slow blow fuse

Resistivity MeasurementRange 0.1-18.3 megohm-cm [temperature compensated to 25°C (77°F)]Accuracy ± 3 % FSCell 0.1 constantDisplay Digital

Notes:1

NANOpure Bioresearch will produce Type I water using pretreated water (RO, DI, Distilled) or high quality tap water provided feedwatersuitability is qualified by laboratory analysis and recommended feed flowrate is maintained.

2Flowrates are dependent on operating conditions and filter usage. Flowrates will also depend on filter compaction.

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The NANOpure Bioresearch deionization systemcan be used on pretreated or high quality tap water.Some municipal tap water supplies contain a veryhigh concentration of suspended particulates,colloids, dissolved organic and inorganic materialsthat should be removed by pretreatment before thewater is processed by the NANOpure Bioresearch.If you plan to use tap water feed for yourNANOpure Bioresearch, Barnstead encourages theuse of our water analysis service to verify feedwatersuitability. A sample collection kit may be obtainedby contacting any of our offices or your preferredlaboratory supply dealer.

The NANOpure Bioresearch includes two 0.2Micron Final Filters, but requires expendablepretreatment and deionization cartridges and FinalFilters for the Remote Dispenser which are notsupplied with the unit and must be purchasedseparately. These expendables are available asindividual components or in an expendable kit (seeTable 1).

Your NANOpure Bioresearch is supplied with apre-wired jumper in the “pump interlock” connector.Installation of options D0603, D0606 (Float Switch)or D2706 (Pressure Switch) require removal of thisjumper plug. DO NOT discard this plug; it will beneeded for certain maintenance operations.

All models are provided with a power cord andplug to be connected to a standard groundedelectrical outlet. Refer to TECHNICAL

Installation

Table 1 Expendable Kit

D5026 NANOpure Bioresearch Pretreat Feed 4-Cartridge Expendables Kit with ORGANICfree

1 D0836 Pretreatment MACROpure Cartridge2 D5027 Ultrapure SG Cartridge1 D5021 ORGANICfree Cartridge2 D3751 Remote Dispenser Filter

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SPECIFICATIONS and Figures M, N & O (pages49-51) in this instruction manual for the electricalrequirements.

UnpackingUnpack the NANOpure Bioresearch carefully.

Remove all contents carefully. Included with thepackaging is a box containing the 4 canisters, O-rings, handle rings, an ultrafilter, 0.2 micron FinalFilters, tubing, fittings, the power cord, a filler panel,a display wall bracket, a 10 foot display cable, aSanitization Cartridge and the Remote Dispenser.Inspect packaging for additional materials beforediscarding. Lift the NANOpure Bioresearch carefullyfrom box, holding onto either the mounting bracketor bench stand. Lay the NANOpure Bioresearch onits back. Remove the canisters, handle rings and O-rings from the packaging and set aside. Do notinstall until told to do so.

Choosing a SiteThe NANOpure Bioresearch system features

remote controls and dispenser allowing system tobe mounted almost anywhere within the laboratory.

INSTALLATION

Figure B NANOpure Bioresearch Outlets

WarningTo avoid electrical shock,use with a properly groundedelectrical outlet of correctvoltage and current handlingcapacity.

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Use mounting bracket for wall mounted systems astemplate to drill mounting holes. (The NANOpureBioresearch does not include screws and fastenersfor mounting.) Allow a minimum of 6 inches (15 cm)clearance on all sides of the unit for servicing and16 inches (40 cm) in front for top cover removal.

Tubing Connector InstallationIn the Mounting and Utility Connections

instructions, you will be instructed to make waterline connections on the NANOpure Bioresearch.Water line connections on the NANOpureBioresearch are made with the included tubingconnector. Use the following procedure wheneveryou are instructed to connect water lines togetherwith a tubing connector.

1. Completely disassemble the fitting. Referto Figure C to familiarize yourself with thenames of the component parts.

2. Make sure the tubing is cut off reasonablysquare and that no plastic burrs or ridgesare present.

3. Place the grab ring and back-up ring in thehex nut in the order and orientation shownin Figure C. Thread the nut onto theconnector. Do not use the O-ring at thistime.

4. Push the tubing through the nut until itbottoms out in the connector.

INSTALLATION

Figure C Typical Polypropylene Tubing Connector Installation

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5. Remove the adapter nut and tubing. Placethe O-ring over the tubing. Be careful notto push the back-up ring or grab ringfurther back on the tubing when installingthe O-ring.

6. Install the hex nut on the connector andhand tighten.

Mounting and Utility Connections

1. Remove the two screws securing the topcover to the NANOpure Bioresearch aswell as the pump interlock plug (Figure B,page 9) and slide the top cover off awayfrom the NANOpure Bioresearch.Familiarize yourself with variouscomponents and install any optionalequipment, i.e. inlet cell, pressure and/orfloat switch. See appropriate section forinstructions.

2. Remove the hold down bolt securing theNANOpure Bioresearch to the wallbracket. It is located on the center of theback wall inside the NANOpureBioresearch cabinet. (Figure B, PAGE 9)

3. Disengage the NANOpure Bioresearchfrom the wall bracket.

4. Remove the packing material from the wallbracket.

5. Use the wall bracket as a template andlocate and drill the mounting holes in themounting surface. A minimum of fourfasteners will be required — two on the topand two on the bottom.

INSTALLATION

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6. Hang the NANOpure Bioresearch unit onthe bracket by sliding the mounting pinsinto the bracket grooves. Reinstall the holddown bolt.

7. Install the top cover by sliding forward.Ensure the pins on the cover align with theholes on the forward cabinet section.Install the top cover screws and theinterlock plug removed in step 1. (SeeFigure B, page 9).

8. Remove the Remote Dispenser frompackaging.

9. Remove the tubing connector from theends of the Remote Dispenser tubing.Retain for use as replacement parts. SeeFigure C, page 10, for identification of theconnector components.

10. Remove the tubing nut, grab ring, backupring and O-ring from Remote Dispenserconnection on NANOpure Bioresearch.Save as replacement parts.

11. Connect the Remote Dispenser tubing toNANOpure Bioresearch at elbowconnections on NANOpure Bioresearch(Figure B, page 9). It is not importantwhich nut on the dispenser is attached towhich connector on the NANOpureBioresearch.

12. Connect 3/8" OD tubing (supplied withunit) to water service.

13. Locate the quick disconnect shutoff valvefitting on the inlet to the NANOpureBioresearch.

WarningWall composition andconstruction, as well asfastener type, must beconsidered when mounting thisunit. The mounting surface andfasteners selected must becapable of supporting aminimum of 275 lbs.Inadequate support and/orfasteners may result indamage to mounting surfaceand/or equipment. If you areunsure of mounting surfacecomposition, condition andconstruction, or correctfasteners, consult your buildingmaintenance group orcontractor.

Do not mount the NANOpureBioresearch directly overequipment that requireselectrical service. Routinemaintenance of this unit mayinvolve water spillage andsubsequent electrical shockhazard if improperly located.

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14. Remove the inlet valve by depressing thestainless steel thumb pad.

15. Remove the tube nut from the valve andslide the nut over the tubing.

16. Wet the tubing with water and slip it overthe hose barb. Tighten the nut.

17. Connect customer supplied tubing to thehose nipple on the ultrafilter flush valve(Figure B, page 9) and route to drain.

18. Connect to electrical service by installingthe electrical cord to the power entrymodule on the right hand portion of theNANOpure Bioresearch (Figure B, page 9)and plugging into a live outlet.

Initial Sanitization and Ultrafilter

Installation1. Perform the following sanitization

procedure utilizing the sanitizationcartridge provided.

a. Remove the sanitization cartridgecontaining the chlorine pellet from theplastic bag and install onto head #1.(See Figure F, page 18, foridentification.)

b. Clean the sealing surfaces of theheads and the top of the canisterswith a clean, wet cloth. Install the O-rings in the O-ring grooves of the 4canisters. Wet the O-rings and installover the sanitization cartridge intocanister position one. Install canisterstwo, three and four without cartridges

INSTALLATION

Do not install the Ultrafilteruntil the NANOpure is readyfor use. If the NANOpure sitsfor longer than 72 hourswithout use, it will becomecontaminated and may effectproduct water quality.

Note

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installed in them by depressing thethumb lever and rotating 1/4 turn tothe right.

Locking pin on canister ring must befully engaged into hole on headbefore system is operated (see FigureD for proper positioning).

c. Ensure that the flush housing is in theremote dispenser. Attach feedwaterline by inserting the quick disconnectvalve into the coupling body andlistening for the click that indicates fullclosure. Place a container below theUltrafiltered Water Drawoff valve tocollect sanitization solution. Openboth the Ultrafiltered Water Drawoffand the Remote Dispenser. Turn theunit on by depressing the ON/OFF/Standby button on the control panel.

d. When the sanitization solution beginsto exit the Ultrafiltered Water Drawoffvalve, close the Ultrafiltered WaterDrawoff valve. Let the solution exit theRemote Dispenser for 30 seconds inthe stream mode. After 30 seconds,change to the spray mode and allowthe unit to spray the solution for anadditional 30 seconds. During this

Figure D Canister Locking Pin Positioning

INSTALLATION

CautionEnsure O-ring is in place inthe canister groove; wetO-ring prior to securingcanister on the head.

Do not tighten canisterhandle ring beyond pointwhere locking pin and pinhole line up.

Secure locking pin beforeoperating. Pin must be fullyengaged before operating.

Do not operate the pumpdry. Dry running will damagethe pump.

Warning

Avoid splashing disinfectingsolutions on clothing or skin.Ensure all pipingconnections are tight toavoid chemical leakage.Always depressurizechemical lines beforedisassembly. Ensureadequate ventilation.Carefully followmanufacturer's safetyinstructions on labels ofchemical containers andmaterial safety data sheets.

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procedure, approximately 60ml aminute of solution will be exiting theUltrafilter Reject Valve. This isnormal.

e. Close the Remote Dispenser andallow the unit to remain inrecirculation for 30-45 minutes.

f. After 30-45 minutes, open theUltrafiltered Water Drawoff valve andthe Remote Dispenser. Allow thesanitizing solution to exit the unit.Leave these valves open forapproximately 5 minutes. A smallquantity of water should be flowingfrom the Ultrafilter Reject Valve.

g. Turn the unit off by depressing theON/OFF/Standby button on thecontrol panel until the display is blank.

h. Allow the system to depressurize.Carefully remove all canisters fromthe system by depressing the thumblever and rotating 1/4 turn to your left.Discard the remaining solution withinthe canister. Do not rinse thecanisters.

i. Disconnect from electrical service andremove the power cord from theNANOpure Bioresearch.

j. Remove the top cover of the unit byremoving the top cover screws andpump interlock cable or jumper plugand pull the cover straight out.

2. Install the ultrafilter by following thesesteps:

INSTALLATION

WarningDepressurize system prior toattempting to removecanisters.

NoteIf you wish to close theconstant bled valve, this canbe done easily before theultrafilter is installed. See"Stopping the ConstantBleed."

The pellet in the sanitizationcartridge may not completelydissolved. This does notconstitute an incompletesanitization. Do not reusespent sanitization cartridge.

Note

NoteDo not install the Ultrafilteruntil the NANOpure is readyfor use. If the NANOpure sitsfor longer than 72 hourswithout use, it will becomecontaminated and may effectproduct water quality.

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a. Remove the ultrafilter housing bypushing up on the clip located at thebottom of the housing and pulling thehousing straight forward.

b. Remove the “T” securing the threepieces of tubing (ultrafilter feed, rejectand product). This is accomplished byunscrewing the nut, which will includethe stainless steel grab ring, back upring and O-ring. Dispose of the “T”connector.

c. Locate and remove the ultrafilter frombox and protective bag.

d. The ultrafilter comes complete withfittings installed. The product, rejectand feed connections are shown inFigure E. Install the ultrafilter into thecradle located on the inside of thehousing removed in step a. Ensurethe orientation is correct. The singlefeed connection must be on top withthe reject and product connections onthe bottom facing the installer.

Figure E Ultrafilter Installation

INSTALLATION

A small amount of 2.0%hydrogen peroxide is used topreserve the filter duringstorage. When removing theultrafilter from the bag,ensure adequate ventilationand wear protective glovesand glasses.

Warning

Reject

Product

Feed

Outlet Cell Well

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e. Secure the ultrafilter into the cradle bytightening the strap around theultrafilter.

f. Remove the nut, stainless steel grab-rings, back-up rings and O-rings fromultrafilter connections and discard.(See Figure C, page 10, for partidentification.)

g. Secure proper tubing to connectionson the ultrafilter. The feed tubing isconnected on the outlet cell well.Attach the loose end of this tubing tothe top connector on the ultrafilter.The reject and product connectionsare located on the bottom of theultrafilter. The reject connection is theupper and outside most of these twofittings. Attach the free end of thetubing attached to the reject valve tothe reject connection on the ultrafilter.Attach the product tubing connectedto the Ultrafiltered Water Drawoff(Figure E, page16) to the lower andmore center of the two bottomconnections on the ultrafilter.

h. Reattach ultrafilter housing completewith ultrafilter and attached tubing toNANOpure cabinet. Install the topcover by sliding it forward. Ensurepins on cover, align with holes onforward cabinet section. Install topcover screws and interlock plugpreviously removed.

INSTALLATION

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Initial OperationInstall and rinse cartridges and filters as follows:1. Install a D0836 pretreatment cartridge,

with the small opening up, into canisterposition one (Figure F). Replace canisterstwo, three and four.

Locking pin on canister handle ring must be fullyengaged into hole on head before system isoperated (see Figure D, page 14, for properpositioning).

2. Connect electrical service by installingelectrical cord to power entry module onthe right hand portion of the NANOpureBioresearch. (Figure B, page 9.)

3. Open the Ultrafilter Flush Valve and theRemote Dispenser valve. (Ensure that thesystem flush housing is in RemoteDispenser prior to rinsing.) Turn the unit onby depressing the ON/OFF/Standby buttonon the control panel until the pump isenergized and the display begins to readnumbers; this will open inlet solenoid valve

Figure F Cartridge Sequence

Initial Operation

Caution

Ensure O-ring is in place inthe canister groove; wetO-ring prior to securingcanister on the head.

Do not tighten canisterhandle ring beyond pointwhere locking pin and pinhole line up.

Secure locking pin beforeoperating. Pin must be fullyengaged before operating.

Note

An extra set of head-to-canister O-rings aresupplied. These can be usedto replace any O-rings thatmay have been damaged ordeformed.

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and supply water to the NANOpureBioresearch. Allow to run to drain for 15minutes through the Remote Dispenserand the Ultrafilter Flush Valve.

4. Turn off system power and open RemoteDispenser and Ultrafiltered Water Draw-offvalve to depressurize system prior toremoving the canisters.

5. Remove the canisters in positions two,three, and four and pour out water. Rinseif required.

6. Install remaining cartridges as shown inFigure F, page 18, and Table 2.

7. Turn the unit on by depressing the ON/OFF/Standby button on the control paneluntil the pump is energized and the displaybegins to read numbers. Allow water torun to drain for 5 minutes. Close RemoteDispenser valve.

8. With Ultrafilter Flush Valve open (Figure B,page 9), allow reject water to run to drainfor five minutes.

Table 2 Correct Cartridge Sequence

INITIAL OPERATION

Do not operate the pump dry- dry running will damage thepump.

Caution

WarningDepressurize system prior toattempting to removecanisters.

CautionImproper rinsing of ultrafiltermay result in cartridgedamage.

Pretreated Feed Standard Cartridge Kit Catalog Number D5026

Position Type Catalog no.1234

PretreatmentUltrapure SGUltrapure SGORGANICfree

D0836D5027D5027D5021

Note

The correct sequence ofcartridges is important inproducing the desired qualityof water.

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9. Leave Ultrafilter Flush Valve open andopen Ultrafiltered Water Drawoff valve(Figure B, page 9). Allow product andreject to run to drain for five minutes.

10. With Ultrafiltered Water Drawoff valveopen, close Ultrafilter Flush Valve andallow product to run to drain for twentyminutes.

11. Turn the unit off by depressing the ON/OFF/Standby button on the control paneluntil the display is blank. Open RemoteDispenser valve and Ultrafiltered WaterDrawoff valve to depressurize system.

12. Install a new 0.2 Micron Final Filter byremoving the filter from the package andplacing it onto the Luer connector on theUltrafiltered Water Drawoff valve. Gentlyturn the 0.2 Micron Final Filter clockwiseuntil it is fully seated on the Luer fitting.

13. Remove system flush housing fromRemote Dispenser and save for futureuse.

INITIAL OPERATION

Figure G Remote Dispenser Final Filter Installation

CautionDo not handle filter by Luerconnector. Care must betaken to preventcontamination of filter whilehandling.

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14. Install a D3751, 0.2 Micron Final Filter intoRemote Dispenser by sliding filter intogrooves on side of dispenser (Figure G,page 20).

15. Turn the unit on by depressing the ON/OFF/Standby button on the control paneluntil the pump is energized and the displaybegins to read numbers. Allowapproximately 8 liters of water to run todrain through the Remote Dispenser torinse the D3751, 0.2 Micron Final Filter.

16. Close Remote Dispenser and allowsystem to recirculate until desired purity isachieved.

17. Rinse 50 to 100 mls of water to drainthrough Remote Dispenser Final Filterbefore each use.

18. Rinse several liters of water to drainthrough the Ultrafiltered Water Drawoff 0.2Micron Final Filter. The NANOpure systemis now ready for use.

INITIAL OPERATION

NoteAlways wet O-rings beforeinstalling 0.2 Micron FinalFilter into Remote Dispenser.

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For best results and optimization of cartridge life,it is recommended that the NANOpure Bioresearchbe left in the standby mode during periods of non-use. The standby mode is designed toautomatically recirculate water through the entireNANOpure Bioresearch system (even RemoteDispenser) for 10 minutes of each hour of inactivity.Standby mode is accessed by pushing “On/Standby/Off” membrane switch on controls untildisplay reads “SbY.” Ensure adequate water supplyis available to NANOpure Bioresearch when theunit is in standby.

The NANOpure Bioresearch is equipped with aconstant bleed of the ultrafiltered reject water. Thisbleed provides for approximately 60 ml of ultrafilterreject water being constantly sent to drain. This willoccur whenever the pump is on both during drawoffand recirculation. This bleed will shorten yourcartridge life due to the extra volume of water beingprocessed by the cartridges.

Because of the unique design and flow paths ofthe NANOpure Bioresearch System, we believethat the unit can operate with little or no appreciablechange in product water quality without this bleedunder most conditions. If you feel the bleed is notrequired, you can easily stop it. Refer to theappropriate section of this manual.

Normal Operation

Figure H Display Indicators

Indicator Lights

Display

Membrane Switches

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NANOpure Bioresearch normal operation is withthe electronics set in the resistivity mode. Themeter automatically compensates readings to 25°C.If the resistivity falls below the programmed setpoint (see selecting the set point), the display willflash numerals.

When the NANOpure Bioresearch display reads“Err,” it is an indication that there is air in the systemor a problem in the resistivity monitoring system.Please refer to the troubleshooting section at theback of this manual for problem identification andsolution. On initial startup, the unit will read “ERR”until water has passed through the system and outthe Remote Dispenser.

Modes of Operation

The NANOpure Bioresearch has one membranepanel with three switches which control itsfunctions.

• Mode Allows you to choose fromresistivity, set point, or temperature.

• Control Allows you to change set pointvalues, check resistivity meter calibration,or monitor optional inlet cell.

• On/Standby/Off Allows you to turn unit on,off or operate unit in standby mode.

Turning Unit On or Off• To turn unit on, press the “On/Standby/Off”

membrane switch once. The display willlight.

Smart Purity Meter

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• To turn unit off, press “On/Standby/Off”membrane switch until the displaybecomes blank.

Selecting the Set PointThe NANOpure Bioresearch electronics include auser programmable set point which alerts you whenwater quality falls below the programmed set point.The set point is user selectable from 0.1 megohm-cm to 18.3 megohm-cm. The display will flashnumerals when actual resistivity measurement is ator below programmed set point.

1. Push the “Mode” membrane switch untilthe orange light (Figure H, page 22) is litalongside the set point indicator. Presetset point in electronics will appear ondisplay.

2. To change the set point, press and holdthe “Control” membrane switch and thenpress the “Mode” membrane switch. Theset point display will automatically begin toscroll backward. To reverse the scrolling,release the “Control” membrane switchuntil the desired set point is attained.

3. When the desired set point is reached,release the “Mode” switch. The NANOpureBioresearch electronics will automaticallyretain the set point until you re-enter theset point mode and repeat the procedure.

SMART PURITY METER

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Displaying the Temperature

To display the water temperature, simply pushthe “Mode” switch until the orange light is litalongside the “Temp °C” indicator. The display willnow read the water temperature in degreescentigrade.

Checking the Calibration

The NANOpure Bioresearch system is equippedwith a manual electronics calibration check whichallows you to verify meter accuracy.

1. Ensure that the reference/inlet cell toggleswitch inside the top housing (Figure I,page 26) is in the reference position.

2. Ensure that the display is in the resistivitymode.

3. Depress and hold the control switch onuntil a reading is given.

If the electronics are within calibration, thereading will be between 9.7 and 10.3 megohm-cmfor resistivity. If the reading is not between thesevalues, call Barnstead|Thermolyne CustomerService for further assistance.

SMART PURITY METER

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Installation

The NANOpure Bioresearch system offers as anoptional feature the ability to monitor the resistivityat the NANOpure Bioresearch inlet water. To installthe inlet cell:

1. Disconnect feedwater supply. Open theRemote Dispenser valve to depressurizeunit.

2. Remove the power cord. Remove thepump interlock plug or the pump protector.Remove the cover screws. Pull the topcover straight out and remove.

3. Install cell (part no. E550X1A) into theNANOpure Bioresearch inlet cell well(Figure I) by removing plug from top ofinlet cell well.

4. Thread the cell cable including all leadwires through NANOpure Bioresearchsystem as shown in Figure I.

Inlet Cell

NoteTo disrupt the flow of waterto the NANOpureBioresearch, remove theinlet valve by depressing thestainless steel thumb pad.The insert with the valve iseasily removed. To resupplythe NANOpure Bioresearchwith water, push the insertinto the coupling body andlisten for the click thatindicates full closure.

NoteE550X1A includes 1/2" NPSthreaded bushing and an O-ring.

Figure I Inlet Cell Installation

Path ofInlet CellCable toPrintedCircuitBoard

Inlet Cell Well

Terminal Block

Reference/Inlet CellToggle Switch

27

5. Wire cell to inlet cell terminal (Figure I,page 26) according to wiring schemeshown in Table 3.

6. Ensure that the reference/inlet cell toggleswitch is in the inlet cell position.

7. Reinstall the top cover, power cord andthe pump interlock cable or jumper plug.Resupply feedwater to the NANOpureBioresearch.

8. Operate normally.

Inlet Cell OperationTo monitor inlet cell readings, select the proper

mode and depress and hold the “control” switch.The reading shown on the display will be for theinlet cell and will revert to the primary cell whenswitch is released.

Table 3 Inlet Cell Wire Connections

INLET CELL

Cell lead Terminal block positionWhiteRedBlack

Position 1Position 2Position 3

28

The NANOpure Bioresearch includes as astandard feature the ability to remotely mount theelectronic control display up to 10 feet away bymeans of an umbilical cord included with each unit.

1. Disconnect from electrical service andremove the power cord from theNANOpure Bioresearch.

2. Remove the top cover of the unit byremoving the top cover screws and thepump interlock cable or jumper plug andpull the cover straight out.

3. Locate the 10 ft. display interconnectcable. Remove the 6" cord from itsconnection points on the main circuitboard and the display unit.

4. Remove the display unit from the mountingbracket by pulling the display straight upuntil pins on back line up with mountingholes then pull straight forward.

5. Attach the 10 foot cord to the connector onthe main circuit board and route theinterconnect cable through the NANOpureBioresearch as shown in Figure J.

Remote Display Mounting

Figure J Remote Display Mounting

10 foot display cable

Filler panel

29

6. A bracket is supplied to permanentlymount the display in a remote location.Attach the bracket to the desired locationwith user supplied screws. Attach thecable to the display and attach the displayto the bracket by lining up the mountingpins on display with bracket grooves.

7. A filler panel is supplied to fill the void leftwhen the display is removed. Prior toattaching the filler panel, move themounting bracket forward by looseningand reattaching the mounting screws.

8. Remove the screws from filler panel andreassemble through the slots on themounting bracket.

9. Reinstall the top cover and reattach thecover screws as well as the power cord,and the pump interlock cable or jumperplug.

REMOTE DISPLAY MOUNTING

30

Each NANOpure Bioresearch system includes aRemote Dispenser unit. The Remote Dispenser isshipped with a system flush housing installed. Thishousing is to be used during cartridge rinsing andsanitization procedures. The dispenser incorporatesan easy to use thumb wheel dispensingmechanism. This thumb wheel mechanism isdesigned to deliver a steady stream when thethumb wheel is completely forward; drop by dropwhen it is slightly forward of the center; and spraywhen it is back. When the thumb wheel is in thecenter, water will be in recirculation (no water out ofdispenser).

NoteDo not discard system flushhousing after initial cartridgerinsing. Keep for futurecartridge changes andsanitization procedures.

Remote Dispenser

31

Accessories D0603, D0606 (float switches) andD2706 (pressure switch) are designed to protectthe NANOpure Bioresearch pump by alerting theNANOpure Bioresearch of an inadequate feedwatercondition so that the pump can be shut down. Usethe following instructions for installation.

1. Disconnect from electrical service.

2. If using the D0603 or D0606 float switch,follow the installation instructions includedwith the unit for installation to tank.

3. If using the D2706 low pressure switch,install the PVC tee (supplied with D2706)into the incoming water line (Figure K).Screw the switch into the top of the tee,then connect the inlet tubing to NANOpureBioresearch with the remaining opening. Itis recommended that a customer suppliedshutoff valve should be added ahead ofthe switch.

4. Route the cable from float or low pressureswitch either above or below NANOpureBioresearch cover (Figure K).

Installing Float or PressureSwitch

Figure K Pump Protector/Pressure Switch Installation

32

INSTALLING FLOAT OR PRESSURE SWITCH

5. Remove the jumper plug and save forfuture use.

6. Plug the cable into jumper plug outlet.

7. Reconnect the electrical cord.

33

Replacing Cartridges

When the resistivity of the water drops below thedesired level, change all of the cartridges together.

1. Disconnect from electrical service.

2. Open the Remote Dispenser valve and theUltrafiltered Water Drawoff valve todepressurize the system. Close the valve.

3. Place a container under the cartridgecanister to collect any spillage.

4. Carefully remove the canister from thehead by depressing thumb lever androtating the canister from right to left 1/4turn. Pull cartridge from head and discard,drain the canister into a container.

5. Install and rinse new cartridges asexplained in INITIAL OPERATION section.

Replacing the Remote Dispenser0.2 Micron Final Filter

It is recommended that the Remote Dispenser0.2 micron Final Filter be replaced every 45 days,when there is an unacceptable bacteria passage orwhen flow decreases to less than one liter perminute. To replace the Remote Dispenser 0.2micron Final Filter

1. Turn the unit off by depressing the ON/OFF/Standby button on the control paneluntil the display is blank.

2. Open Remote Dispenser valve andUltrafiltered Water Drawoff valve todepressurize system.

Maintenance and Servicing

Warning

Disconnect from the powersupply prior to maintenanceand servicing.

Refer servicing to qualifiedpersonnel.

WarningDepressurize system prior toattempting to removecanisters.

34

3. Remove the old Remote Dispenser 0.2Micron Final Filter by pushing it towardsopen grooves on dispenser(Figure G, page 20).

4. Wet O-rings to allow new RemoteDispenser 0.2 Micron Final Filter to slideeasily into place.

5. Install the new Remote Dispenser 0.2Micron Final Filter into dispenser byinserting into grooves as shown inFigure G, page 20.

6. Rinse 6 to 10 liters of D.I. water to drainthrough filter.

Replacing the Ultrafiltered WaterDrawoff 0.2 Micron Final Filter

Replace the Ultrafiltered Water Drawoff 0.2Micron Final Filter whenever any of the followingconditions occur: every 30 days, the product water

MAINTENANCE AND SERVICING

Use care when handling thenew Ultrafiltered WaterDrawoff 0.2 Micron FinalFilter assembly to preventenvironmental contaminationof filter.

Note

Ultrafiltered Water Drawoff 0.2 Micron Filter Installation

NoteIf a newly installed 0.2micron filter clogs rapidlyafter installation, theNANOpure Bioresearch mayneed to be sanitized toremove bacterialcontaminants. See SystemSanitization.

Use care when handling thenew Remote Dispenser 0.2Micron Final Filter assemblyto prevent environmentalcontamination of filter.

Note

35

flow is reduced or bacteria and/or pyrogen breakthrough. The Ultrafiltered Water Drawoff 0.2 MicronFinal Filter is shipped assembled with a bell. Toreplace the Ultrafiltered Water Drawoff 0.2 micronfilter assembly:

1. Remove the old Ultrafiltered WaterDrawoff 0.2 micron filter assembly byturning it counterclockwise until it is freefrom the Luer fitting.

2. Remove the new Ultrafiltered WaterDrawoff 0.2 Micron Final Filter assemblyfrom its bag and insert it into the Luerfitting. Gently turn it clockwise until it isfully seated in the Luer fitting.

3. Rinse at least 5 liters of water through theUltrafiltered Water Drawoff 0.2 MicronFinal Filter to drain prior to using theproduct water.

Replacing Fuses

Main Fuse ReplacementThe “main fuse” is located in a fuse holder at the

upper right side of the top housing. To access,remove top cover, squeeze the clip on the fuseholder and remove. Replace with a slow blow 2ampere fuse for 230 VAC units and a slow blow 3ampere fuse for 100 or 115 VAC units. The fusesare labeled. To reassemble, simply insert the fusein the fuse holder and push the fuse holder until itsnaps into place.

MAINTENANCE AND SERVICING

Warning

Replace fuses with those ofthe same type and rating.

NoteIf a newly installed 0.2micron filter clogs rapidlyafter installation, theNANOpure Bioresearch mayneed to be sanitized toremove bacterialcontaminants. See SystemSanitization.

Caution

Do not overtighten theUltrafiltered Water Drawoff0.2 Micron Final Filterassembly onto the Luerfitting or use excessive forcein seating it. The filter and/orLuer fitting can be damagedby overtightening orexcessive force.

36

Printed Circuit Fuse ReplacementThe “printed circuit fuse” is located in a fuse

holder on the front of the printed circuit board.Replace this device with the appropriate fuse aslisted in the spare parts list.

System Sanitization

Frequency of cleaning is difficult to determinebecause of the wide variety of feedwater supplieswhich can be used, but the need for cleaning canbe easily determined. Whenever cartridges arereplaced, perform a sanitization procedure utilizingthe D50223 sanitization cartridge, a new, easy-to-use sanitization cartridge.

1. Turn the unit off by depressing the ON/OFF/Standby button on the control paneluntil the display is blank. Disconnect thepower from electrical service.

2. Open the Remote Dispenser and theUltrafiltered Water Drawoff to depressurizethe system prior to attempting to removethe canisters.

3. Remove the Remote Dispenser 0.2 MicronFinal Filter and insert the empty flushhousing. Remove the Ultrafiltered WaterDrawoff 0.2 micron filter.

4. With the cartridges removed from thecanisters, wash the inside of the canistersand the inside heads with soap ordetergent, using a sponge or clean cloth.Rinse out the canisters and the heads withclean water several times to remove thedetergent residues.

MAINTENANCE AND SERVICING

WarningDepressurize system prior toattempting to removecanisters.

37

5. Remove the sanitization cartridgecontaining the chlorine pellet from theplastic bag and install onto head #1.

6. Install the four canisters onto the heads bydepressing the thumb lever and rotating1/4 turn to the right.

7. Place a container under the ultrafilteredwater drawoff to collect the sanitizationsolution. Open both the Ultrafiltered WaterDrawoff and the Remote Dispenser. Turnon power to the unit.

8. When the sanitization solution begins toexit the Ultrafiltered Water Drawoff, closethe Ultrafiltered Water Drawoff. Let thesolution exit the Remote Dispenser for 30seconds in the stream mode. After 30seconds, change to the spray mode andallow the unit to spray the solution for anadditional 30 seconds.

9. Close the Remote Dispenser and allow theunit to remain in recirculation for 30-45minutes. During recirculation, a smallamount of sanitization solution will exit theNANOpure Bioresearch constant bleedline (if not closed off).

10. After 30-45 minutes, open the UltrafilteredWater Drawoff and the Remote Dispenser.Allow the sanitizing solution to exit theunit. Leave these valves open forapproximately 5 minutes.

11. Turn the unit off by depressing the ON/OFF/Standby button on the control paneluntil the display is blank.

MAINTENANCE AND SERVICING

The pellet in the sanitizationcartridge may not havecompletely dissolved. Thatdoes not constitute anincomplete sanitization. Donot reuse spent sanitizationcartridge.

Note

Warning

Avoid splashing disinfectingsolutions on clothing or skin.Ensure all pipingconnections are tight toavoid chemical leakage.Always depressurizechemical lines beforedisassembly. Ensureadequate ventilation.Carefully followmanufacturer's safetyinstructions on labels ofchemical containers andmaterial safety data sheets.

CautionSecure locking pin beforeoperating. Pin must be fullyengaged before operating.

Ensure O-ring is in place inthe groove and wet O-ringprior to securing the canisteron the head.

38

12. Allow the system to depressurize.Carefully remove all canisters from thesystem by depressing the thumb lever androtating 1/4 turn to your left. Discard theremaining solutions within the canister. Donot rinse the canisters.

13. Install fresh cartridges in the system asindicated in Initial Operation under"Replacing Cartridges." Do not reinstallused cartridges (they may contain largeamounts of bacteria).

14. Press the control panel “on/off” button tostart the pump and fill the system. Runwater through the system to drain anyremaining disinfecting solution. A flush of10 liters is sufficient.

15. Close the Remote Dispenser valve, andallow the resistivity of the water to riseabove the “set point” setting on theresistivity meter. Install and rinse a newRemote Dispenser 0.2 Micron Final Filteras indicated under "Replacing TheRemote Dispenser 0.2 Micron Final Filter."

16. Install and rinse a new Ultrafiltered WaterDrawoff 0.2 micron filter as indicated underReplacing the Ultrafiltered Water Drawoff0.2 Micron Filter.

Cleaning the Resistivity Cell

Disconnect from electrical service. Disconnectinlet valve and tubing and depressurize system.Remove top cover screws and slide top covertoward you. Remove the ultrafilter housing bypushing up on the clip located at the bottom of the

WarningDepressurize system prior toattempting to removecanisters.

CautionEnsure O-ring is in place inthe groove and wet O-ringprior to securing the canisteron the head.

Secure locking pin beforeoperating. Pin must be fullyengaged before operating.

39

housing and pulling the housing straight forward.Disconnect tubing at outlet cell well. Also,disconnect and remove tubing connected toultrafilter flush valve assembly. Carefully removethe power supply microprocessor circuit board.Disconnect three cell leads at the printed circuitboard connector and gently pull cable down throughgrommet toward the cell. Unscrew and remove thecell. Carefully remove O-ring to clean cell.

Wash the cell in a mild detergent solution or a10% inorganic acid solution (follow acidmanufacturers recommended handling procedure).This may be done in an ultrasonic cleaner or with asoft brush. The cell must be thoroughly rinsed indeionized or distilled water following the detergentor acid cleaning.

After cleaning, check O-ring on cell, replace ifnecessary. Reinstall cell into cell well and handtighten. Reroute cable up through housing andreconnect leads. Refer to wiring diagram for properlead terminal position. Replace power supplymicroprocessor circuit board and ultrafilter housing.Reconnect tubing to outlet cell well and flush valveassembly. Replace top cover.

Shutdown

If NANOpure Bioresearch is to be shut down foran extended period of time, the system should becompletely drained and the cartridges, the ultrafilterand final filters removed to prevent the growth ofbacteria.

If the system has remained inactive and full ofwater, then the system should be drained, sanitizedand new cartridges and final filters installed prior touse.

MAINTENANCE AND SERVICING

WarningAvoid splashing disinfectingsolutions on clothing or skin.Ensure all pipingconnections are tight toavoid chemical leakage.Always depressurizechemical lines beforedisassembly. Ensureadequate ventilation.Carefully followmanufacturer’s safetyinstructions on labels ofchemical containers andmaterial safety data sheets.

40

Stopping the Constant Bleed

To stop the constant bleed of the NANOpureBioresearch system, make the followingmodification:

1. Disconnect the power to the system andremove the power cord and pump interlockcable or jumper plug located on the righthand portion of the NANOpureBioresearch.

2. Remove the top cover of the unit byremoving the top cover lock screws andpulling the top cover straight out.

3. Remove the ultrafilter housing by pushingup on the clip located at the bottom of thehousing and pulling the housing straightforward.

4. Close the valve attached to the elbowlocated at the center of the NANOpureBioresearch cabinet.

5. Reattach the ultrafilter housing to theNANOpure Bioresearch cabinet.

6. Replace top cover and secure coverscrews.

7. Reconnect power cord and reinstall pumpinterlock plug or pump protector.

MAINTENANCE AND SERVICING

41

Troubleshooting Guide

Problem Possible Causes Solutions

NANOpure Bioresearchcompletely inactive (pump notoperating, control panel not lit,etc.).

No electrical power toNANOpure Bioresearch.

Main fuse blown.

Ensure that the NANOpureBioresearch power cord isconnected to a live powersource and completelyplugged into electrical outlet

Replace the main fuse asindicated in the REPLACINGFUSES section (page 22).

Pump runs, but no display (nodigital display).

Printed circuit fuse blown.

Printed circuit board inter-connect cable disconnected.

Replace the printed circuitfuse as indicated in theREPLACING FUSES section(page 22).

Reconnect cable.

Reduced or no product flowfrom the Remote Dispenser.

0.2 micron final filter clogged. Replace the Final Filter asindicated in the REPLACINGTHE REMOTE DISPENSER0.2 MICRON FINAL FILTERsection (page 21).

Leaking canisters. Large o-ring in canister ismissing, damaged or notsealed properly.

Loose Head/Canister fit.

Replace or position correctly.

Tighten handle ring.

Pump does not run. Displaylight.

Pump protector (in reservoir),feedwater line pressure switchor jumper plug not connectedto pump interlock.

Connect the pump protector orpressure switch cord to thereceptacle located inside topcover. If a Barnstead pressureswitch is installed in thefeedwater line, the pump willnot start until the line pressurerises to 0.35 kg/cm2 (5 psi).

Open the feedwater line shutoff valve or fill the feedwaterreservoir.

Make sure the jumper plug isinstalled.

42

TROUBLESHOOTING GUIDE

Problem Possible Causes Solutions

Recirculated water will notrinse up to desired purity level.

Exhausted cartridge.

Cartridges out of order.

Cartridges upside down.

Feed water bypassingcartridge(s).

Check valve malfunctioning.

Replace all the cartridges asindicated in the REPLACINGCARTRIDGES section (page21).

Install the cartridges in theproper order as indicated inthe INITIAL OPERATIONsection (page 13).

Install the cartridges right sideup as indicated In the INITIALOPERATION section (page13).

Be sure that small O-ringinside head is not damagedand is properly installed.

Remove tubing from checkvalve; turn unit on. If waterleaks from end of check valve,wash to remove anyparticulates.

Display reads "Err" whenchecking resistivity.

Resistivity cell disconnected orwired improperly.

Air in system.

System electronics or cell outof calibration.

Check resistivity cell wiring.

Purge air from system byopening Remote Dispenserand/or Ultrafiltered WaterDrawoff.

Check resistivity of referencecell. If resistivity displayed isnot between 9.7 and 10.3electronics need recalibration.If resistivity reading is proper,clean cell and reinstall. Ifproblem persists, replace cell.

No constant reject out ofUltrafilter reject.

Blocked reject flow device. Remove flow restrictive deviceand back flush.

Display reads E_A. System electronics failure. Replace main PC board.

43

TROUBLESHOOTING GUIDE

Problem Possible Causes Solutions

Short cartridge life. Cartridges being used arebeyond expiration date.

Change in feedwatercharacteristics.

Check the expiration date.Cartridges begin to losecapacity after being stored twoyears from the date ofmanufacture. Replace thecartridges with unexpiredones.

If a Barnstead ROpure is thefeedwater source, check thatthe membrane is functioningproperly.

If a Barnstead Still is thefeedwater source, ensure thatthe distillate temperature tothe NANOpure Bioresearchdoes not exceed 49°C(120°F).

If tap water is the feedwatersource, check the quality ofthe water. In some cases thequality of the water will changewith the seasons. Changingthe source (city water to wellwater, or well water to citywater) will result in a waterquality change.

If feedwater is from a centralwater purification system,verify water quality and properfunctioning of the system.

44

Replacement Parts Listing

Recommended Spares

Consumables

Consumable parts are those required to support the day-to-day operation of thisequipment.Barnstead |Thermolyne establishes two types of consumables; those items that mustperiodically be replaced to maintain performance (filters, resin cartridges, etc.) and otheritems of limited life (indicator lights, fuses, etc.) that you can expect to replace on a more orless random basis. Where practical, Barnstead |Thermolyne recommends the frequency ofreplacement, or provides information on life expectancy from which you may calculate areplacement interval compatible with your usage pattern.

The replacement of consumable parts is discussed in the Maintenance and Servicingsection to assist you in accomplishing your own service.

Consumables may be ordered separately and in some cases, as an expendables kit.Check with your Barnstead/Thermolyne representative for additional information on theexpendables kit.

Description Catalog No. Recommended QuantityUltrafilter Water Drawoff Final FilterRemote Dispenser Final FilterPretreatment CartridgeUltrapure SG CartridgeOrganicFree Cartridge3.0 Ampere Slow Blow Fuse, 115 Volt2.0 Ampere Slow Blow Fuse, 230 VoltTeflon® Tape, RollPrinted Circuit Board Fuse, 100, 120VPrinted Circuit Board Fuse, 240VSanitization Cartridges (pkg of 3)

FL703X2D3751D0836D5027D5021044550442006078FZX43FZX48D50223

22121111111

45

General Maintenance PartsGeneral maintenance parts are defined as laboratory level repair parts which do not

require great expertise or special tools for installation. Barnstead |Thermolyne recommendsthat you stock the general maintenance parts as an aid to ensuring the continued operationof this equipment.

REPLACEMENT PARTS LISTING

Description Catalog No. Recommended QuantityO-ring (between heads)O-ring (head-to-canister)O-ring (head-to-cartridge)Fastener PinConnector (head to head)Adapter (head end)Check Valve1/4" O.D. x 1/4" NPT ConnectorQuick Disconnect Inlet Valve

Body 1/4 NPTInsert 3/8 tube

06440GSX28GSX27FP550X1BR550X4BR550X20221405931

CUX8CUX9

24421111

11

Safety StockFor critical applications where performance with minimum downtime is required,

Barnstead |Thermolyne recommends that you maintain a local stock of those parts listed inthe General Maintenance parts and Safety Stock sections.

® Registered trademark of Dupont.

Description Catalog No. Recommended QuantityResistivity DisplayMain PC Board 100 & 120 VACMain PC Board 240 VACRecirculation Pump & Motor 100 & 120 VACRecirculation Pump & Motor 240 VACCartridge Canister HeadCartridge Canister Handle RingCartridge CanisterPressure RegulatorResistivity CellInlet Solenoid Valve

100V and 120V 240V

SW550X1APC550X1APC747X2APU733X1APU733X2ABK550X2HN550X1ACS550X102280E550X1A

RY747X1ARY747X2A

1111111111

11

Flush ValveRestrictor

02273PMX99

11

46

Please refer to the Specification Plate for thecomplete model number, serial number, and seriesnumber when requesting service, replacementparts or in any correspondence concerning this unit.

All parts listed herein may be ordered from theBarnstead|Thermolyne dealer from whom youpurchased this unit or can be obtained promptlyfrom the factory. When service or replacement partsare needed we ask that you check first with yourdealer. If the dealer cannot handle your request,then contact our Customer Service Department at319-556-2241 or 800-553-0039.

Prior to returning any materials toBarnstead|Thermolyne Corp., please contact ourCustomer Service Department for a “Return GoodsAuthorization” number (RGA). Material returnedwithout a RGA number will be refused.

Ordering Procedures

47

Exploded View100 & 120 Volt Models

Figure L Exploded View

Key Part # Description1 DL687X1A Top cover2 05766 1/4" OD x 1/4 NPT Elbow3 PU733X1A Pump assembly, 100/120V4 CRX72 Cord set 100/120V5 04247 Pump interlock plug6 CUX8 Quick Disconnect7 CUX9 Quick Disconnect Insert8 PC550X3A PC board, reference call9 SW550X1A Display10 WH550X2 Interconnect cable 10' (WH550X1 6")11 PC550X1A Main PC board, 100/120V12 02280 Pressure reducing valve13 02214 Stainless steel check valve14 BR550X2 Head end fitting15 06440 O-ring between heads16 FP550X1 Head connector pins17 BR550X4 Head connector18 BK550X2 Head19 GSX27 Head o-ring20 GSX28 Head to canister o-ring21 HN550X1A Canister handle ring22 CS550X1 Canister23 CV747X1A Auxiliary Drawoff24 PM703X3 Luer Connector25 DL630X18 Ultrafilter housing26 E550X1A Resistivity cell27 CS895X3 Remote Dispenser30 GSX29 O-ring31 D4740 Floor stand32 CEX172 Power Entry Module33 CAX44 Filter, Power Supply34 RY747X1A 100/120V Solenoid Valve

Not ShownTN687X1A Transformer02273 Ultrafilter Flush ValvePMX99 Constant Bleed RestrictorFL703X2 Filter

48

Exploded View240 Volt Models

Key Part # Description1 DL687X1A Top cover2 05766 1/4" OD x 1/4 NPT Elbow3 PU733X2A Pump assembly, 240V4 CRX70 Cord set 240V5 04247 Pump interlock plug6 CUX8 Quick Disconnect7 CUX9 Quick Disconnect Insert8 PC550X3A PC board, reference call9 SW550X1A Display10 WH550X2 Interconnect cable 10' (WH550X1 6")11 PC747X2A Main PC board, 240V12 02280 Pressure reducing valve13 02214 Stainless steel check valve14 BR550X2 Head end fitting15 06440 O-ring between heads16 FP550X1 Head connector pins17 BR550X4 Head connector18 BK550X2 Head19 GSX27 Head o-ring20 GSX28 Head to canister o-ring21 HN550X1A Canister handle ring22 CS550X1 Canister23 CV747X1A Auxiliary Drawoff24 PM703X3 Luer Connector25 DL630X18 Ultrafilter housing26 E550X1A Resistivity cell27 CS895X3 Remote Dispenser30 GSX29 O-ring31 D4740 Floor stand32 CEX172 Power Entry Module33 CAX44 Filter, Power Supply34 RY7472A Solenoid Valve

Not Shown02273 Ultrafilter Flush ValvePMX99 Constant Bleed RestrictorFL703X2 Filter

49

Wiring Diagrams

Figure M Wiring Diagram for 100V Model

50Figure N Wiring Diagram for 120V Model

WIRING DIAGRAMS

51

WIRING DIAGRAMS

Figure O Wiring Diagram for 230V Model

52

Barnstead Thermolyne2555 Kerper Blvd.P.O. Box 797Dubuque, IA 52004-0797 USAPHONE: 319-556-2241 • 800-553-0039FAX: 319-589-0516E-Mail: mkt@barnsteadthermolyne.com

a subsidiary of

Barnstead|Thermolyne Corporation warrants that if a product manufactured byBarnstead|Thermolyne and sold by it within the continental United States or Canadaproves to be defective in material or construction, it will provide you, without charge, for aperiod of ninety (90) days, the labor, and a period of one (1) year, the parts, necessary toremedy any such defect. Outside the continental United States and Canada, the warrantyprovides, for one (1) year, the parts necessary to remedy any such defect. The warrantyperiod shall commence either six (6) months following the date the product is sold byBarnstead|Thermolyne or on the date it is purchased by the original retail consumer,whichever date occurs first.

All warranty inspections and repairs must be performed by and parts obtained froman authorized Barnstead|Thermolyne dealer or Barnstead|Thermolyne (at its owndiscretion). Heating elements, however, because of their susceptibility to overheating andcontamination, must be returned to our factory, and if, upon inspection, it is concluded thatfailure is not due to excessive high temperature or contamination, warranty replacement willbe provided by Barnstead|Thermolyne . The name of the authorizedBarnstead|Thermolyne dealer nearest you may be obtained by calling 1-800-446-6060 orwriting to:

Barnstead|ThermolyneP.O. Box 797

2555 Kerper BoulevardDubuque, IA 52004-0797

USAFAX: (319) 589-0516

E-MAIL ADDRESS: mkt@barnsteadthermolyne.comBarnstead|Thermolyne’s sole obligation with respect to its product shall be to repair

or (at its own discretion) replace the product. Under no circumstances shall it be liable forincidental or consequential damage.

THE WARRANTY STATED HEREIN IS THE SOLE WARRANTY APPLICABLE TOBarnstead|Thermolyne PRODUCTS. Barnstead|Thermolyne EXPRESSLY DISCLAIMSANY AND ALL OTHER WARRANTIES, EXPRESSED OR IMPLIED, INCLUDINGWARRANTIES OF MERCHANTABILITY OR FITNESS FOR USE.

One Year Limited Warranty