Healing America’s Wounded Warriors

Luke BeckmanExecutive Director, TBI & PTSD Project,

Director of Outreach and Social Media, International Hyperbaric Medical Foundationlukembeckman@gmail.com, 650-740-5853, http://www.razoo.com/story/Nbirr

Overview• Why are so many wounded?• What is Post-Traumatic Stress Disorder/Traumatic

Brain Injury (PTSD/TBI)?• What will this cost the American taxpayer?• What are we currently doing?• What is Hyperbaric Oxygen Therapy (HBOT)?• What is the National Brain Injury Rescue and

Rehabilitation (NBIRR) Project?• How do we properly heal our veterans?

Our Veterans Need Help

• As of Jan. 2010, 1.9 million service members had deployed to Iraq and Afghanistan.

• It is estimated that 1/3 of these service members suffer from Traumatic Brain Injury (TBI), Post-Traumatic Stress Disorder (PTSD), and/or depression.– 600,000 service members

Source: RAND Corporation

Why so many injured?

• Improvised Explosive Devices (IEDs) are responsible for 60% of all American combat casualties in Iraq and 50% of all combat casualties in Afghanistan.

• Modern battlefield medicine is able to keep more service members alive after major injuries.

• Many service members have both visible and hidden injuries from head trauma- especially from the blast waves from IEDs.

Source: http://www.fas.org/sgp/crs/weapons/RS22330.pdf

What are Traumatic Brain Injury (TBI) and Post-Traumatic Stress Disorder (PTSD)?

• Both TBI & PTSD are closely related, and in many cases, directly related.• Explosions, by way of direct impact or form a blast wave, injures the brain- usually when

it ricochets off of the skull.• Blast-induced TBI is different than traditional brain injuries because of compounded

PTSD causal factors• Many symptoms of TBI are identical to symptoms of PTSD

– Depression– Anxiety– Forgetfulness– Sleep difficulties– Difficulty concentrating– Muscle spasms– Irritability– Headache– Nausea– Fatigue

• Affects both the military and civilians

What does this mean for U.S. security?

• We have 600,000 service members with wounds to the head (whether they show it or not)

• Most of these individuals experience mild to severe psychological and physical symptoms yet still serve on the frontlines

• We do not yet have a way to heal these wounds

What are the military costs of PTSD/TBI to American taxpayers?

Military Costs to Taxpayers

Lifetime disability/medical costs for one brain-injured veteran $1,250,000Lost tax revenue from each veteran $500,000Lost tax revenue from the veteran's primary caregiver $500,000Total taxpayer costs per one wounded veteran $2,250,000Estimated # of PTSD/TBI veterans from Iraq and Afghanistan 600,000Total taxpayer cost of 600,000 brain injured veterans $1,350,000,000,000Military cost of war in Iraq* $705,940,000,000Military cost of war in Afghanistan* $315,840,000,000Total cost of both wars $1,021,780,000,000

Source: http://www.fas.org/sgp/crs/natsec/RL33110.pdf

These values do not include the costs of replacing trained soldiers with new ones*Cost only accounts for direct military war-fighting operations

Cost of Traumatic Brain Injury (TBI) in American society as a whole

Civilian Numbers on TBI as of Fall 2010

# of Americans living with a traumatic brain injury 5,300,000# of Americans who will suffer a head injury this year 2,500,000# of Americans who will be hospitalized from their injury 500,000# of deaths caused by brain injury 50,000# of TBI survivors per year 80,000Total lifetime cost to treat one person with brain injury $2,250,000Total cost of Traumatic Brain Injury to American society (non-military) $17,550 trillion

Source: Johns Hopkins Medicine

What treatments is the military using to treat brain injured veterans?

• Exercise• Balance• Hand-Eye-Coordination• Cognitive Rehabilitation• Medication (individuals often take up to 20 different

types of drugs daily)• NONE of the drugs currently used and paid for by

Tricare and the VA to treat brain injured veterans are FDA-approved to treat TBI (only Paxil and Zoloft are approved to treat PTSD)

Where will we be 10 years from now?

• Total cost of $1.35 Trillion dollars to American taxpayers using current methodologies

• An estimated 15,500 veterans have committed suicide since Aug 2008 (17 suicides per day)

• The military openly declares they have a suicide epidemic– Almost all drugs that are prescribed (Note: they are prescribed

off-label) for PTSD carry Black-Box warnings against sustained use because of increased risk of suicide

• Using current treatments, a person who is reduced to 70% brain capacity often increases to 74% and still remains heavily dependent and addicted to medications.

What alternatives exist?

• Hyperbaric Oxygen Therapy

What is Hyperbaric Oxygen Therapy (HBOT)?

• The process of breathing in 100% pressurized oxygen.

• Used daily for 13 FDA-approved conditions– Stroke, diabetic foot wounds, burns, crush injuries,

carbon monoxide poisoning, etc…

Why isn’t HBOT used widely?• HBOT at 1.5 atmospheres is not covered by insurance and military personnel

cannot afford a full treatment cycle.• Active opposition and stalling from the US military for a myriad of reasons (reasons

below actually stated in open dialogue)- none of which are rational and/or true– HBOT for TBI and PTSD is dangerous.– HBOT is not clinically proven to work.– HBOT is not an FDA-approved device for TBI or PTSD– You haven’t done a clinical trial with a placebo as part of the protocol.– No matter how much evidence you gather, it is not backed by clinical trials.– These people would have gotten better anyway.– The brain cannot be healed.– You can’t prove that it was HBOT that caused the improvements.– If it worked, military medicine would have already adopted it.– We haven’t studied it enough.– You’re biased in favor of HBOT; therefore, anything you say is suspect.– Too many of the patients who say they have a problem really don’t.– You’re out of your league. DOD will run the studies their way.– You’re giving these patients false hope.– HBOT leads to premature aging and Alzheimer's.– We’ve spent over a billion dollars on research and studies.– We’re doing all that is humanly possible.

• The most logical argument is that if HBOT is proved effective, thousands of soldiers could be pulled off the front lines for treatment– Our current policy is to provide them with dozens of drugs- used off-label.

The US military is concerned about frontline readiness

• The US Army has fears about troops “leaving the fight” when they hear that treatments exist for their head injuries– There's more TBI/PTSD out there than reported– Soldiers have not been reporting claims and the Army isn't keeping track– Without baseline data there is no way to "prove" that TBI and/or PTSD existed

[Congress has mandated that baseline tests be given]– Far too many new cases would be suspicious claims– The system could not handle the surge of claimed injuries– Once the "true" nature of TBI/PTSD occurrence was known, the volunteer Army

would be threatened– A sizeable number of boots-on-the-ground in Afghanistan would have to be

pulled out of the line for past injury and every time a new injury occurred, again threatening the volunteer force.

• Several military combatant commanders are, however, pushing very hard to get their soldiers treated.

NBIRR is the Solution

• The National Brain Injury Rescue and Rehabilitation (NBIRR) Project has been launched to carry out a clinical trial for HBOT to treat TBI/PTSD– Approved by the Western Institutional Review Board-

the “Gold Standard” of medical review– Case study of 1,000 patients to build the pool of data to

conduct proper analysis• Treatments have begun on a sporadic basis with

remarkable results using 1.5 atmospheres of pressure (HBOT 1.5)

What does HBOT 1.5 mean?

• Patient enters chamber (enclosed glass tube) and lies down

• Breathes 100% oxygen, at 1.5 atmospheres of pressure, for one hour

• 40 sessions over six weeks– Patients typically begin to experience positive

symptoms after 20 sessions• 30-day break• 40 more sessions

What is HBOT’s potential effect on the brain?

• 84% of coma patients have awoken with exposure to HBOT 1.5

• HBOT is the only non-hormonal FDA-approved treatment known to repair and regenerate human tissue.

• HBOT repairs and regenerates tissue by two oxygen-dependent processes– Activates growth factors at the DNA level– Improves blood supply to wounds throughout the

body.

Initial treatment results are encouraging

• Consistent results: All patients who have been treated to-date by HBOT 1.5 have been able to return to pre-injury jobs

• MRI and SPECT scans show dramatic increased production in previously-damaged areas of the brain

• Automated Neurological Assessment Metrics show significant improved performance in treated service members

What do improved test scores really mean?

• When comparing behavior after treatment to after the injury was sustained…– Both simple and complex reaction time is faster– Learning and memory is improved– Headaches subsided– Sleep patterns and length is improved– Depression is decreased– Cognitive functioning is improved

How do we scale, test, and validate this therapy?

• HR396 was written and proposed on the U.S. House of Representatives floor but removed from the DoD appropriations bill– Would have mandated a five-year pilot program to attempt new treatments

like HBOT in wounded veterans– All injured veterans would have been notified– Army lobbying removed this bill from the overall funding package

• Over 80 facilities are registered and approved with the IRB study- they can treat 1,000 patients in under six months.

• With the enactment of the NBIRR study, Bayesian analysis on a small number of patients will likely demonstrate results on how the rest of treatments will proceed

• This study on service members is the first step to generating the data set to allow the FDA to approve HBOT for TBI in the civilian population

What is the cost and where does the money go?

• Using free-standing, approved clinics will save millions of dollars

• One hour in a private hospital chamber costs around $1,300• One hour in an NBIRR-approved clinic chamber (all are lined up, ready

to go) costs $200– This is a $88,000 savings for every patient treated

• Total treatment cost per patient is $20,000 from start to finish– 1000 patients will be enrolled in the study (lasting six months

total)– Administrative fees over the six months across the entire country

• Total cost is $20,000,000 ($20,000 x 1000)

What is the cost and where does the money go?

One hour in a private hospital hyperbaric chamber $1,300Total cost of entire NBIRR HBOT 1.5 study if conducted in private hospitals $108,000,000Total medical savings using private clinics vs. hospitals $88,000,000One hour in an NBIRR private clinic chamber $200Total number of patients in NBIRR study 1,000Number of treatments 80Cost of 80 treatment for 1,000 patients $16,000,000Administrative costs for 80 clinics across the country for six months $4,000,000

Total cost of entire NBIRR HBOT 1.5 study $20,000,000

What stands in our way?

• Tricare and the VA will not reimburse HBOT treatments because they are not FDA-approved for brain injury– Note: NONE of the drugs currently used and paid

for by Tricare and the VA to treat our brain injured veterans are FDA- approved to treat TBI.

What are the ultimate end goals?1. Demonstrate the efficacy of HBOT in treating

TBI/PTSD and in doing so…2. Ensure that Tricare and the VA accept HBOT 1.5

for treating TBI as a covered medical procedure3. Heal our 600,000+ brain injured veterans and

get them back to functional lives4. Expand healthcare coverage across civilian

insurance providers and ensure treatment to 7,000,000+ civilians suffering from TBI

How can you help?

• Donate money to fund the study– 20,000,000 people donating $1 funds the entire study– 1,000,000 people donating $20 funds the entire study– 100,000 people donating $200 funds the entire study– 16,000 people donating $1,000 funds the entire study

• The average American spends…– $323 per year on tobacco– $457 on alcohol– $558 on personal care– $2,698 on entertainment

Think about itCost of medicating veterans with current methods $1,350,000,000,000Cost of healing brain injured veterans with HBOT $9,600,000,000

Total Savings to the American Taxpayer by using HBOT $1,340,400,000,000

17 veterans are killing themselves every day

We can heal the brain

It only takes $20

100% of your donation goes directly to treating wounded veterans

Donate Here: http://www.razoo.com/story/Nbirr

Thank you for caring…

Luke BeckmanExecutive Director, TBI & PTSD Project,

Director of Outreach and Social Media, International Hyperbaric Medical Foundationlukembeckman@gmail.com, 650-740-5853

http://www.razoo.com/story/Nbirr

This We’ll DefendSemper Fi

Honor, Courage, CommitmentService Before Self

Semper Paratus