Treat Your Building as a Patient: Environmental Reduction of … · 2016. 6. 20. · Treat Your...
Transcript of Treat Your Building as a Patient: Environmental Reduction of … · 2016. 6. 20. · Treat Your...
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TTreat Your Building as a Patient: Environmental Reduction of
Bacteria Through Continuous Visible Light Disinfection
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What is Indigo-CleanTM?• An overhead light fixture which continuously and
safely disinfects the environment using visible light
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Indigo-OnlyMixed-White
White Disinfection Mode = Ambient White Light + Disinfection
Indigo Disinfection Mode = Increased Disinfection Only
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What is Visible Light Disinfection?
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How Does Indigo-Clean Work?
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3. Pathogen inactivation breaks the environmental chain of infection 4. Measured bacterial reduction*
*Maclean M., et. al. Environmental decontamination of a hospital isolation room using high -intensity narrow-spectrum light, J. Hosp. Infection Vol. 76, pp. 247-251 (2010)
1. Continuous, automatic, safe system creates hostile environment for bacteria
2. Environment creates Reactive Oxygen Species within bacteria causing inactivation
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Bringing Innovation to Lighting and Healthcare
• History of disinfection science dating back to Joseph Lister
• Lengthy investment in visible light disinfection technology (10+ years)
• Academic acceptance of technology
• Prototypes and clinical trials
• 50 years of lighting challenging environments
• Experience in healthcare lighting
• Knowledge of infection prevention
• Listings & certifications
• Clinical Evaluation experience
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History of Academic Research & Investment in Visible Light Disinfection
Research TimelineMore than 30
refereed publications
and proceedings since 2008
Visible Light Disinfection
Commercially Available
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Potential Healthcare Applications
Waiting Areas
Patient Rooms
Sterile Processing Oncology
OR
Bone Marrow
TransplantWound
Care Clinics
Triage/ Trauma
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Why Indigo-Clean in the OR?
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IImproving Environmental HHygiene
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Clostridium difficile> 5 months to years
Methicillin resistant Staph. aureus (MRSA)
>12 months
MDR – Gram negative (e.gAcinetobacter)
> 30 months
Vancomycin Resistant Enterococci (VRE)
> 46 months
Norovirus> 2 weeks
MDROs Persist in the Environment
Adapted from Kramer et. al. BMC Infect Dis 2006;6:130
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Bacterial Reservoirs Exist in the OR• Top 5 High Touch Areas
• Anesthesia Computer Mouse
• OR Bed• Nurse Computer Mouse• OR Door• Anesthesia Medical Cart
• Top 5 Growth Areas• Nurse Computer Keyboard• Anesthesia Computer
Mouse• OR Push Plate• Anesthesia Medical Cart
Drawer• OR Bed
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Link, T., et al. “Determining high touch areas in the operating room with levels of contamination”, AJIC 2016; Article in Press
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Cleaning Can Be Improved in Many Operating RoomsDespite the best efforts of environmental services……75% of environmental surfaces remain contaminated even after terminal cleaning1… ...and 17% of OR surfaces contained bacterial pathogens2
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1Jefferson J., et al. “A novel technique for identifying opportunities to improve environmental hygiene in the operating room”, AORN J 2011;93:358-3642Munoz-Price LS, et. al. “Decreasing operating room environmental pathogen contamination through improved cleaning practices”, Infect Control Hosp Epidemiol2012;33:897-904
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No Touch Disinfection Technology
• Continuous• Air Filters • UV/Plasma air handlers• Copper surfaces• Environmental sprays• Visible Light
• Episodic• UV Devices• Chemical Vapor
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Episodic vs. Continuous or (Apples vs. Oranges)Episodic (UV)
• Useful in outbreak or terminal cleaning applications
• Often takes the room out of service
• Potential safety issues• Potential compliance
issues
Continuous (Visible)• Useful in areas which
must remain operational 24/7
• Capacity Limitations• Quick Turnover
• Cleans even when people aren’t in the room
• Designed to be safe for patients and staff
• Eliminates compliance issues
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EEpisodic vs. Continuous DDisinfection
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Episodic vs. Continuous- Definition
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Continuous
= Total Bacteria Killed(High-Level Continuous-Ideal, but not practical)
= Total Bacteria Killed(Episodic- Practical implementation of ideal solution)
= Total Bacteria Killed(Low-Level Continuous-Compliment to Episodic)
“Continuous Disinfection Fills the Gaps”
(Bac
teria
Kill
ed/T
ime)
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Effects of Disinfection Upon Bacteria Levels
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High
Low
Bact
eria
Leve
ls
Time
Episodic Disinfection Applied
Average Bacteria Level (w/Episodic
Disinfection Only)
Continuous Disinfection Applied
Average Bacteria Level (w/Episodic + Continuous
Disinfection)
Regrowth
Net Gain from Continuous Disinfection
“Log X Kill”
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Which is Better?
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CClinical Implementation oof Indigo-Clean
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Clinical Implementation of Indigo-CleanTM
• Overhead light fixtures which continuously and safely disinfect the environment using visible light
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Indigo-OnlyMixed White
Wall switch can be used to select desired mode
OROccupancy/
Vacancy control can automatically switch
between modes
White Disinfection Mode =Ambient White Light + Disinfection
Indigo Disinfection Mode = Increased Disinfection Only
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Indigo-CleanIn An Operating Room
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Airborne Pathogens
Variety of Surfaces Hard to Reach
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CCurrent Evaluation Data ffor Indigo-Clean
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ESKAPE Pathogens• Enterococcus faecalis• Staphylococcal Aureus*
(including MRSA)1
• Klebsiella pneumoniae• Acinetobacter baumannii• Pseudomonas aeruginosa• Enterobacter species
Demonstrated Laboratory Susceptibility to Visible Light Disinfection
Gram-Positive Bacteria• Clostridium perfringens• Staphylococcus epidermidis (CONS)• Staphylococcus hyicus (CONS)• Streptococcus pyogenes• Listeria monocytogenes• Mycobacterium terrae• Corynebacterium striatumGram-Negative Bacteria• Proteus vulgaris• Escherichia coli (E. coli)• Campylobacter jejuni• Salmonella enteritidis• Shigella sonnei• Serratia sppYeast & Filamentous Fungi• Aspergillus niger• Candida albicans• Saccharomyces cerevisiaeBacterial Endospores• Clostridium difficile• Bacillus cereus
*= Demonstrated clinical susceptibility to presumptive S. Aureus & MRSA
1Maclean M., et. al. Environmental decontamination of a hospital isolation room using high-intensity narrow-spectrum light, J. Hosp. Infection Vol. 76, pp. 247-251 (2010)
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Significant reduction of total bacterial contamination on surfaces around the room (2-day use)
76% reduction
86% reduction
All reductions in bacterial contamination were achieved over and above standard cleaning and infection control practices
Whole Room Results Surface-Specific Results
Bacterial reduction on a range of surfaces before and after use of the Visible Light Disinfection
Glasgow Royal Infirmary: Intensive Care Unit (Initial Studies)2
2Maclean M., et. al. Continuous decontamination of an intensive care isolation room during patient occupancy using 405nm light technology. Journal of Infection Prevention, 14(5); 176- 181 (2013)
Lights Off
Lights On
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Additional Publication Data
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For a full list of available publications, please visit:
http://www.indigo-clean.com/resources-white-papers
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Froedtert & The Medical College of Wisconsin Froedtert Hospital• GI Diagnostic Waiting Area
• Easier to show a reduction due to high amount of bacteria
• Proximity to procedure rooms
• Approximately 450 ft.2(Equivalent to small OR)
• Results consistent with previously published patient room results
• Additional studies underway
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Clinical Results for Indigo-CleanTM
• Inactivation of S. aureus in Waiting Room
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70%+ Decrease
“In Phase 2 of the trial, where the lighting deployment was optimized across the room, we were able to improve the bacterial reduction to more than 70%.”
- Dr. Nathan Ledeboer, Associate Professor of Pathology, Medical College of Wisconsin
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Clinical Success at MCW/Froedtert
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Clinical and Commercial Success!• State-of-the-art
facilities in Las Vegas and other unannounced locations
• Henderson Hospital-Universal Health Services Inc.
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“Even the lights will get into the safety prevention with special indigo lighting built into the ceilings that will kill bacteria”
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Your Invitation to Join the Clinical Partners Program
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