University of Colorado Hospital

Trauma-Burn Service Line Report

FY 2018

Hospital Overview/Executive Summary _______________________________________________________________ 1

Total Trauma-Burn and Critically Injured Patient Volume ____________________________ 2

Traumatic Mechanisms of Injury _______________________________________________ 3

Burn Center Admissions _____________________________________________________ 4

Burn Center Clinic and Operative Cases ________________________________________ 5

Geriatric Trauma/Discharge Disposition _________________________________________ 6

Trauma and Burn Mortality Rates ______________________________________________ 7

Trauma and Burn Referrals __________________________________________________ 8

Injury Prevention _________________________________________________________ 9-10

Trauma and Burn Outreach _________________________________________________ 11

Alina Miller ______________________________________________________________ 12

Jamie Ketchum ___________________________________________________________ 13

Trauma Research Programs _______________________________________________ 14-18

Publications ___________________________________________________________ 19-21

Invited Lectures ________________________________________________________ 22-23

Research Presentations __________________________________________________ 24-25

Awards and Achievements __________________________________________________ 26

Leadership Positions ____________________________________________________ 27-28

Student and Resident Mentorship __________________________________________ 29-30

Contents

Page | 1

Trauma-Burn 2014 – 2018 Executive Summary

57% increase in total volume since 2014

11% increase within the last year

102% increase in critically injured patients since 2014

20% increase within the last year

67% increase in burn center admissions since 2012

Overall trauma mortality has decreased from 3.1% to 2.7%

75% increase in transfers into UCH since 2014

21% increase in transfers in from outside UCHealth since 2017

In the most seriously injured patients, mortality decreased by 38%

23 publications by Trauma-Burn faculty 2017-2018

University of Colorado Hospital (UCH)

Trauma-Burn Center

American College of Surgeons and State Adult

Level I Trauma Center

Last Survey: July 2018

Anticipated State Survey: September 2019

Anticipated ACS Survey: 2021

Only American Burn Association Verified Burn

Center in the Rocky Mountain Region

Last Survey: July 2018

Anticipated Survey: December 2021

Page | 2

10321192

1276

1453

161916%

7%

14%11%

0

200

400

600

800

1000

1200

1400

1600

1800

FY 2014 FY 2015 FY 2016 FY 2017 FY 2018

UCH Critical Trauma-Burn Volume 102% increase in critically injured patients 2014-2018

Critically injured patients = Injury Severity Score >15 (includes burn)

UCH Trauma-Burn Volume 57% increase in total patient volume 2014-2018

Page | 3

Top 2018 Traumatic Mechanisms of Injury

Blunt74%

Penetrating8%

Thermal18%

Chemical BurnFire/FlameExplosion

Gunshot WoundsStab Wounds

FallMotor Vehicle CrashMotorcycle CrashAssaultBicycle CrashSporting Accident

Page | 4

Burn Center Admissions 67% increase since FY 2012

Page | 5

Burn Center Clinic and Operative Cases

Burn Clinic Visits

Burn Operative Cases

Page | 6

Demographics: Geriatric Admits vs. Non-Geriatric Admits by Fiscal Year 31% of all trauma patients admitted in FY 2018 to UCH are geriatric patients ≥ 65 years of age.

Top Inpatient Discharge Disposition Our goal at discharge is that patients are recovered enough to either go home or into an active

rehabilitation program. In FY 2018, we were able to accomplish this goal 82% of the time. 37%

55%

Page | 7

FY 2014 FY 2015 FY 2016 FY 2017 FY 2018

ISS > 15 16.40% 12.70% 11.20% 11.20% 10.20%

Total 3.10% 2.70% 2.40% 2.30% 2.70%

Trauma Mortality Rates: Total vs. Critically Injured In FY 2018, rortality rates at UCH reflect an overall mortality of 2.7%. This is a decrease in mortality by 38% compared to 2014 even as volume grows. More importantly, the mortality rate in the most critically injured continued to decrease to 10.2%. Of all reporting trauma centers in North America, UCH is in the top 10% for overall trauma mortality.

Page | 8

Referrals In 29% increase in transfers into UCH in the last year.

In 2018, 133 more patients were transferred to UCH compared to 2017. In 2018, the increase in transfers from freestanding EDs and other UCHealth hospitals to UCH was 61 patients; increase in external transfers was 72 patients.

Trauma and Burn Transfers, Excluding UCHealth Facilities In FY 2018, UCH received transfers from nine states, the Netherlands and Mexico.

Page | 9

Injury Prevention Activities

Over 2,500 community members impacted by Outreach efforts!

An elderly fall reduction program

5 seven-week

programs

50 seniors

26 programs

726 students

51 Courses

704 Participants

Robyn Wolverton applies a tourniquet on a 9News anchor for Stop the Bleed Day

UCHealth staff come together in July 2018 to teach Stop the Bleed at Broncos Mile High Stadium

Page | 10

• Electrical Company Injury Prevention

• Frostbite Prevention for the Homeless

• “It Happens in Seconds” Training for fire fighters

• Flame and Chemical Burn Injury Prevention for Glassblowers

• Marijuana Legalization and Butane Hash Oil Burns in Colorado

– State Assembly

Burn Injury Prevention Activities

Page | 11

Trauma and Burn Outreach

Page | 12

An arsonist set fire to Alina Miller's apartment building. She escaped,

but shattered her leg. Then she embarked on a remarkable journey.

Since that horrific day, Alina is now married and influences patients with new amputations through her role at Creative Technology Orthotic & Prosthetic Solutions, where she and another man who has also lost a leg spend time helping people who have lost limbs.

When she jumped, Alina’s bare left foot hit first and took the brunt of the 45-foot fall. Her weight shifted to the right foot, and then she fell straight back, landing hard on concrete which broke her back. “I didn’t open my eyes. I curled up into a ball,’’ she said. “I was overwhelmed with a huge, deep aching pain.’’

An ambulance whisked Alina to nearby UCHealth University of Colorado Hospital on the Anschutz Medical Campus where she received extraordinary care from a multi-disciplinary group of providers who have stood by her side since the day of her injury.

Alina has had a strong support system to help her push through the darkness. In the months and years after the fire, Alina had five more surgeries to repair her shattered foot. Alina Miller has embraced life’s adventures after having her leg amputated, including going wakeboarding.

Her will to persevere and enjoy life despite extreme challenges reminds all of us why the care that we provide to patients at the University of Colorado Hospital Level I Trauma Center is so important. Alina’s courage and extraordinary ambition are truly remarkable.

See Alina’s full story here: https://www.uchealth.org/today/2018/10/05/finding-pearls-fire-forces-4-

story-jump-and-a-woman-embraces-beauty/

Fire forces four-story jump and a woman

embraces beauty…

Page | 13

When a dumptruck collided with the Ketchum's SUV, more than 90

percent of Jamie's body was burned. Her mother, Patti, suffered

more than 60 percent burns and her father was killed. Despite the

odds, Patti’s determination, phenomenal care and extraordinary

people made it possible for Patti to walk out of the hospital after 97

days and 12 OR visits for debridement and grafting. Jamie was

discharged after the longest ever stay in the Burn Center of 425

days. She had approximately 50 operations for debridement, grafting

and reconstruction. To successfully graft all the burned areas,

cultured epithelial cells were grown from a skin biopsy (due to lack of

non-burned skin for donor site) – a specialized procedure not done

by all Burn Centers. Jamie has now learned to walk on her prosthetic

limbs and even plays ice-hockey.

Read more about Jamie’s story here:

https://denver.cbslocal.com/2018/07/24/burn-victim-leaves-uchealth-

longest-stay-ever/

It always seems impossible until it’s done:

Burn patient survives against all odds

Page | 14

In its 26th year, the Trauma Research Center is an international leader of trauma biology,

coagulopathy and personalized treatment though its combination of clinical data analysis, advanced

Omics measurements and rigorous T32 training. Together, surgeons and scientists at UCD continue

to pave the way for decreasing post traumatic mortality rates.

Gastrointestinal, Trauma, Endocrine Surgical Faculty

Anirban Banerjee PhD Program Director

Ernest E. Moore MD

Erik Peltz DO

Mitchell Cohen MD

2017-2018 T32 fellows

Geoff Nunns, Gregory Stettler

Jason Samuels, Julia Coleman

Collaborators

Christopher C. Silliman MD, PhD;

Department of Hematology

Kirk Hansen PhD;

Department of Biochemistry, Molecular Genetics

Angelo D’Alessandro PhD;

Department of Biochemistry, Molecular Genetics

2017-2018 Accomplishments

40 papers

24 scientific presentations

Nearly $4.48 million in Grants,

primarily from NIH and DOD

Trauma Research Center

Page | 15

Dr. Franklin Wright – Trauma QI and Prehospital Research Lab Prehospital Trauma Research Quality Improvement and Process Improvement Projects Optimizing Early Trauma Care (EMS and ED/Trauma Bay)

Team

Franklin L. Wright MD – Assistant Professor

Erik Peltz DO – Assistant Professor

Alicia Heelan Gladden MD – Research Resident

Allie Kovar MD – Research Resident

Medical Student: Jacob Mago, MS4

Accomplishments

5 scientific presentations: 1 international, 3 national, 1 regional, 2 full podium

1 publication, 2 manuscripts in process

Dr. Heelan Gladden awarded Clinical Effectiveness and Patient Safety (CEPS) – resident grant

Dr. Heelan Gladden completed Institute for Healthcare Quality, Safety and Efficiency

Certificate Training Program

Co-Investigator on faculty CEPS grant

Page | 16

Team

Catherine G. Velopulos MD, MHS, FACS – Associate Professor

Heather Carmichael MD – Research Resident

Medical Students and Undergraduate Student:

Allison Moore MS1, Joshua Abolarin MS1

Sara Muramoto MS1, Billy Tran MS3, Lesley McClafferty

Collaborators with Colorado Department of Public Health &

Environment

Kirk Bol MSPH

Ethan Jamison MPH

Dr. Catherine Velopulos – Health Services Research Lab Examining Disparities in Surgical Outcomes/Access to Care Hospital Based Violence Intervention Programs/Intimate Partner Violence Geographic Information Systems Mentoring CU-UNITE Urban Underserved Track

Accomplishments Last 12 Months

9 scientific presentations: 7 national, 1 state, 1 institutional, 5 full podium

3 publications, 1 manuscript in final revisions, 6 manuscripts in progress for December

deadlines

6 abstracts accepted for national scientific presentation next 3 months, 2 full podium

Awarded as co-investigator on $950,000 Department of Justice Grant to evaluate Denver

Health Hospital-based Violence Intervention Program At-Risk Intervention and Mentoring (AIM)

Dr. Carmichael sponsored by Scholarships and Other Award Resources (SOAR) for the

American College of Surgeons (ACS) Health Services Research Course

Page | 17

21 active IRBs including:

IV Lidocaine Infusions for Treatment of Pain in Burn Patients

Impact of a Mobile Phone App on Triage and Transfer to a Large Regional Burn Center

Evaluation of Use of t-PA in Treatment of Frostbite

Ambulation in the Adult Burn Population: Perception versus Actuality – $10,000 grant

Burn Trauma and Infection (MICROBIOME)

Randomized Trial of Enteral Glutamine to Minimize Thermal Injury – RE-ENERGIZE

Epicel, Cultured Epidermal Autographs (CEA)

Burn Clinical Trials

Page | 18

Team

Elizabeth J. Kovacs PhD, Professor Juan-Pablo Idrovo MD, Assistant Professor Rachel McMahan PhD, Research Assistant Professor

Trainees – Postdocs, Research Residents, Graduate Students & Staff: Kiran Dyamenahalli MD, PhD Elizabeth Wheatley PhD Devin Boe (MSTP student) Holly Hulsebus MPH (PhD student) Kevin Najarro MS (Lab Manager) Juliet Mullen (PRA)

Major Collaborators: Ellen Burnham MD, MS, Mashkoor Choudhry PhD Dan Frank PhD, Anne Wagner MD Arek Wiktor, MD, Sean Colgan, PhD

Multi-organ system response in burn patients and murine models Alcohol intoxication and burn injury (NIH R01) “Inflamm-aging” and the gut-liver-lung lung axis after burn (NIH R01) Mesenchymal stem cells and inflammation after burn (NIH R21)

Alcohol and lung immunity in the aged (New NIH R21)

Accomplishments Last 12 Months

7 scientific presentations: 1 presidential address, 1 international conference, 2 national conference, 3 University 10 manuscripts published/in press, 17 abstracts presented at national/international conferences, 6 oral

presentations, 4 travel awards, 1 poster selected as best poster among 460 posters Grants

Continuing: NIH, NIA R01 age & burn YR15; NIGMS R01 alcohol & burn YR18; NIAAA R1 MSC & burn YR2; NIAAA R13 meetings grant YR6

New & approved to fund: NIAAA R21 alcohol & aging; VA merit award burn & biomarkers; NIAAA R13 meetings grant

Pending: NIGMS R35 MIRA burn & microbiome

Fellowships submitted: NIH F31 H Hulsebus (age alcohol); NIH K08 J-P Idrovo (age, burn & liver)

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Page | 19

1. Nunns GR, Moore EE, Chapman MP, Moore HB, Stettler GR, Peltz E, Burlew CC, Silliman CC, Banerjee A, Sauaia A. The Hypercoagulability Paradox of Chronic Kidney Disease: The Role of Fibrinogen. Am J Surg 2017; 214: 1215-1218 epub. PMID: 28951066. NIHMSID 908400.

2. Regner J, Cothren-Burlew C, McIntyre R, Reckard P, Melo N, Peltz E, Dissanaike S, Karimi K,

Cribari, C, Behnfield C, Dunn J, Butler L, Margulies D. Outpatient Laparoscopic Appendectomy

Can Be Successfully Performed for Uncomplicated Appendicitis: A Southwestern Surgical

Congress Multicenter Trial. Am J Surg 2017; 214:1007-1009

3. Shackford SR, Dunne CE, Karmy-Jones R, Long W, 3rd, Teso D, Schreiber MA, Watson J, Watson C, McIntyre RC, Jr., Ferrigno L, Shapiro ML, Southerland K, Dunn JA, Reckard P, Scalea TM, Brenner M, Teeter WA. The evolution of care improves outcome in blunt thoracic aortic injury: A Western Trauma Association multicenter study. J Trauma Acute Care Surgery 2017; 83: 1006-1013.

4. Clendenen N, Nunns GR, Moore EE, Reisz JA, Gonzalez E, Peltz E, Silliman CC, Fragoso M, Nemkov T, Wither MJ, Hansen K, Banerjee A, Moore HB, D'Alessandro A. Hemorrhagic shock and tissue injury drive distinct plasma metabolome derangements in swine. J Trauma Acute Care Surgery. 2017; 83: 635-642.

5. Bookman K, West D, Ginde A, Wiler J, McIntyre R, Hammes A, Carlson N, Steinbruner D, Solley M, Zane R. Embedded clinical decision support in electronic health record decreases use of high-cost imaging in the emergency department: Embed study. Acad Emerg Med 2017; 24: 839-845.

6. Bergese SD, Mestek ML, Kelley SD, McIntyre R, Jr., Uribe AA, Sethi R, Watson JN, Addison PS. Multicenter study validating accuracy of a continuous respiratory rate measurement derived from pulse oximetry: A comparison with capnography. Anesthesia and Analgesia. 2017; 124: 1153-1159.

7. Lin Y, Meguid R, Hosokawa PW, Henderson WG, Schulick RD, Shelstad RC, Wild TT, McIntyre RC. An Institutional Analysis of Unplanned Return to the Operating Room to Identify Areas for Quality Improvement. Am J Surg 2017; 214: 1-6.

8. Reisz JA, Slaughter AL, Culp-Hill R, Moore EE, Silliman CC, Fragoso M, Peltz ED, Hansen KC, Banerjee A, D'Alessandro A. Red blood cells in hemorrhagic shock: a critical role for glutaminolysis in fueling alanine transamination in rats. Blood Adv. 2017;1 : 1296-1305. doi: 10.1182/bloodadvances.2017007187. eCollection 2017 Jul 25. PMID: 29296771

9. Morton AP, Moore EE, Moore HB, Gonzalez E, Chapman MP, Peltz E, Banerjee A, Silliman C. Hemoglobin-based oxygen carriers promote systemic hyperfibrinolysis that is both dependent and independent of plasmin. J Surg Res. 2017; 213: 166-170. doi: 10.1016/j.jss.2015.04.077. Epub 2015 Apr 25. PMID: 28601310

10. Slaughter AL, Nunns GR, D'Alessandro A, Banerjee A, Hansen KC, Moore EE, Silliman CC,

Nemkov T, Moore HB, Fragoso M, Leasia K, Peltz ED. “The Metabolopathy of Tissue Injury,

Hemorrhagic Shock and Resuscitation in a Rat Model.” Shock 2018; 49: 580-590. PMID:

28727610. NIHMSID: 893069.

Publications

Page | 20

11. Velopulos CG, Shihab HM, Lottenberg L, Feinman M, Raja A, Salomone J, Haut ER. Prehospital spine immobilization/spinal motion restriction in penetrating trauma: A practice management guideline from the eastern association for the surgery of trauma (EAST). J Trauma Acute Care Surgery. 2018; 84:736-744.

12. Davis S, McIntyre R, Cribari C, Dunn J. Thyroid storm induced by trauma: A challenging combination. Am Surg. 2018; 84: e44-e46.

13. Callcut R, Kornblith L, Conroy A, Robles A, Meizoso J, Namias N, Meyer D, Haymaker A, Truitt M,

Agrawal V, Haan J, Lightwine K, Porter J, San Roman J, Biffl W, Hayashi M, Sise M, Badiee J,

Recinos G, Inaban K, Schroeppel T, Callaghan E, Dunn J, Godin S, McIntyre R, Peltz E, O’Neill

P, Diven C, Scifres A, Cross A, West M, Storrs S, Cullinane D, Cordova J, Moore E, Moore H,

A Privette A, Eriksson E, and Cohen M. The Why and How Our Trauma Patients Die: A

Prospective Multicenter Western Trauma Association Study. J Trauma Acute Care Surgery.

2018 in press.

14. Heelan Gladden AA, Peltz ED, McIntyre RC Jr, Vega S, Krell R, Velopulos C, Ferrigno L,

Wright FL. Effect of Pre-Hospital Use of the Assessment of Blood Consumption Score and Pre-

Thawed Fresh Frozen Plasma on Resuscitation and Trauma Mortality. J Am Coll Surg 2018

S1072-7515(18)32183-5. doi: 10.1016/j.jamcollsurg.2018.11.005. [Epub ahead of print]

15. Carmichael H, Jamison E, Bol KA, McIntyre R Jr, Velopulos CG. Premeditated versus

"passionate": patterns of homicide related to intimate partner violence. J Surg Res 2018. 230:

87-93. doi: 10.1016/j.jss.2018.04.050. Epub 2018 May 25.

16. AlSulaim HA, Haring RS, Asemota AO, Smart BJ, Canner JK, Ejaz A, Efron DT, Velopulos CG,

Haut ER, Schneider EB. Conscious status is associated with the likelihood of trauma centre

care and mortality in patients with moderate-to-severe traumatic brain injury. Brain Inj 2018;

32: 784-793

17. Wiktor AJ, Madsen L, Carmichael H, Smith T, Zanyk S, Amani H, Wagner AL. Multiregional

Utilization of a Mobile Device App for Triage and Transfer of Burn Patients. J Burn Care Res.

2018; 39: 858-862.

18. Mueller SW, Baumgartner LJ, MacLaren R, Neumann R, Wiktor AJ, Kiser TH, Lindberg G,

Cava L, Fish DN, Janoff EN. Divergent humoral responses to 23-valent pneumococcal

polysaccharide vaccine in critically-ill burn and neurosurgical patients. PLoS One. 2018; 13:

e0197037. doi: 10.1371/journal.pone.0197037. eCollection 2018. PMID: 29758059

19. Tignanelli CJ, Wiktor AJ, Vatsaas CJ, Sachdev G, Heung M, Park PK, Raghavendran K,

Napolitano LM. Outcomes of Acute Kidney Injury in Patients With Severe ARDS Due to

Influenza A(H1N1) pdm09 Virus. Am J Crit Care. 2018; 27: 67-73. doi: 10.4037/ajcc2018901.

20. Stettler GR, Kemp C, Wright F, Peltz E. Delayed presentation of complete arterial transection

treated with interposition graft: A case report. Trauma Case Rep. 2018; 18: 24-27. doi:

10.1016/j.tcr.2018.11.008. eCollection 2018 Dec. PMID: 30519625

Page | 21

21. Stettler GR, Moore EE, Nunns GR, Chandler J, Peltz E, Silliman CC, Banerjee A, Sauaia A. Rotational thromboelastometry thresholds for patients at risk for massive transfusion. J Surg Res. 2018; 228: 154-159. doi: 10.1016/j.jss.2018.03.027. Epub 2018 Apr 11. PMID: 29907206

22. Banerjee A, Silliman CC, Moore EE, Dzieciatkowska M, Kelher M, Sauaia A, Jones K,

Chapman MP, Gonzalez E, Moore HB, D'Alessandro A, Peltz E, Huebner BE, Einerson P,

Chandler J, Ghasabayan A, Hansen K. Systemic hyperfibrinolysis after trauma: a pilot study

of targeted proteomic analysis of superposed mechanisms in patient plasma. J Trauma

Acute Care Surg. 2018; 84: 929-938. doi: 10.1097/TA.0000000000001878. PMID: 29554044 23. Badulak JH, Schurr M, Sauaia A, Ivashchenko A, Peltz E. Defining the criteria for intubation of

the patient with thermal burns. Burns. 2018; 44: 531-538. doi: 10.1016/j.burns.2018.02.016. Epub 2018 Mar 13. PMID:29548862

Page | 22

1. Dumond, R. BSN, RN, TCRN, AEMT. “Getting Involved with TQIP.” American College of Surgeons TQIP Annual Meeting; Chicago, IL; November 11-13, 2017.

2. Dumond, R. BSN, RN, TCRN, AEMT. “How to Make Your Trauma Team Perform Like a Pit Crew.” 4th Annual Pediatric Trauma Society Annual Meeting; Charleston, SC; November 2-4, 2017.

3. Dumond, R. BSN, RN, TCRN, AEMT. “How to Make Your Trauma Team Perform Like a Pit Crew.” American College of Surgeons Connecticut Committee on Trauma Conference; Uncasville, CT; April 6, 2018.

4. Kovacs, E. PhD. “Basic and translational elderly research.” Annual meeting of the American Burn Association, Chicago, IL, April 2018.

5. Kovacs, E. PhD. “Presidential Address” Shock Society, Scottsdale, AZ, June 2018. 6. Madsen, L. Time Matters: Acute Frostbite Care. University of Colorado Health Trauma and

Emergency Medicine Conference. Colorado Springs, CO, 2017. 7. McIntyre, R. M.D. Panreatic Neuro-endocrine Tumors. Presented at the Montana, Idaho,

Wyoming Chapters of the American College of Surgeons. Jackson Hole, WY. January 26-29, 2017.

8. McIntyre, R. M.D. Improving Quality Improvement. Presented at the Montana, Idaho, Wyoming Chapters of the American College of Surgeons. Jackson Hole, WY. January 26-29, 2017.

9. McIntyre, R. M.D. Frailty and Surgical Outcomes. Presented at the Southwestern Surgical Congress. Maui, HI. April 2-5, 2017.

10. McIntyre, R. M.D. Treating One of Our Own. 9th Annual Western Colorado Trauma Conference. Delta County Memorial Hospital. Delta, CO, May 5, 2017.

11. McIntyre, R. M.D. Geriatric Trauma Care. Rocky Mountain Trauma and Emergency Medicine Conference. Beaver Creek, CO, June 16, 2017.

12. McIntyre, R. M.D. Lectures at the ACS Comprehensive General Surgery Review Course. Thyroid Nodules and Cancer Hyperparathyroidism, Adrenal Neoplasms, Multiple Endocrine Neoplasims, Head and Neck Mass, Cardio-pulmonary perioperative care, Anticoagulation management, Pulmonary Critical Care, Venous Thromboembolism, Cardiac Critical Care, Board Preparation Summary Trauma, Chicago, IL, July 28-31, 2017.

13. McIntyre, R. M.D. Geriatric Trauma Care. University of Colorado Health Trauma and Emergency Medicine Conference. Colorado Springs, CO, August 19, 2017.

14. McIntyre, R. M.D. Small bowel obstruction. MT, ID, WY Chapter American College of Surgeons. Big Sky, MT, January 26-28, 2018.

15. McIntyre, R. M.D. Geriatric Trauma Care. Front Range Trauma and Acute Care Surgery Conference. Arvada, CO, February 22, 2018.

16. McIntyre, R. M.D. Top Ten Critical Care Papers 2017. Rocky Mountain Trauma and Emergency Medicine Conference. Vail, CO, June 9, 2018.

Invited Lectures

Page | 23

17. McIntyre, R. M.D. Lectures at the ACS Comprehensive General Surgery Review Course. Pulmonary Critical Care, Cardiac Critical Care Principles of Managing Neck Mass, Perioperative Care Cardio-pulmonary Care, Perioperative Care Anticoagulation Management, Venous Thromboembolism Prophylaxis and Treatment, Surgical Palliative Care, Thyroid Nodules and Cancer, Hyperparathyroidism, Adrenal Neoplasms, Chicago, IL, July 26-29, 2018.

18. McIntyre, R. M.D. Top Ten Critical Care Papers. UCHealth Trauma EMS Symposium. Colorado Springs, CO, August 25, 2018.

19. Palmieri, T. & Staubli, L. American Burn Association Annual Meeting. Utilizing your Burn Database to Develop QI Projects. 2018.

20. Peltz, E.D. D.O. “Damage Control Laparotomy & Damage Control Resuscitation.” North Dakota State Trauma Conference, Minot, ND, October 2017.

21. Steward, L. M.D. Fundamentals of Critical Care/Critical Care Procedures Course Instructor, University of Colorado School of Medicine: February 2017 and October 2017.

22. Velopulos, C.G. M.D. “Aurora EMS Lecture Series.” Presenter, Aurora, CO, Multiple Dates, 2016-Present.

23. Velopulos, C.G. M.D. Academic Surgical Congress, Moderator - Podium Presentation, Jacksonville, FL, February 2018.

24. Velopulos, C.G. M.D. American College of Surgeons, Discussant - Podium Presentation, San Diego, CA, October 2017.

25. Velopulos, C.G. M.D. EAST Annual Meeting, Moderator - Podium Presentations, Orlando, FL, January 2018.

26. Wagner, A. M.D. Burning Questions. 2017 Colorado State EMS Conference (EMSAC), Keystone, CO.

27. Wagner, A. M.D. Vail Mini-trauma conference, Acute Burn Survival Kit & Care of the Acute Frostbite Patient Vail, CO, 2017.

28. Wagner, A. M.D. Western Region Burn Conference, Frostbite in January… Amputation in July. Breckenridge, CO, 2018.

29. Wagner, A. M.D. Colorado Academy Physician Assistants (CAPA) Conference, Frostbite in January… Amputation in July. Copper Mountain, CO, 2018.

30. Wagner, A. M.D. Western Colorado Trauma Conference, Acute Burn Care Survival Guide, Delta, CO, 2018.

31. Wagner, A. M.D. 4th Annual UCH EMS Conference, Burning Questions Aurora, CO, 2018. 32. Wagner, A. M.D. EMS Mini-conference; Parker Hospital, Burning Questions, Parker, CO, 2018. 33. Wiktor, A. M.D. American Burn Association Annual Conference. Long-terms Outcomes of Elderly: Grief,

Depression, PTSD, 2018. 34. Wiktor, A. M.D. 7th Annual Wilz Trauma Symposium, Burn Care in the ED/Urgent Care and Field

Management of Burns Pueblo, CO, 2018. 35. Wiktor, A. M.D. Marijuana Legalization and Butane Hash Oil Burns: Dangers Posed to EMS -

Colorado State EMS Conference (EMSAC), Keystone, CO, 2017. 36. Wright, F. M.D. “Principles of Damage Control in Trauma.” Great Plains Health Trauma

Conference, September 2017.

Page | 24

1. Almuttawa A MHS, Haut E MD, PhD, Velopulos CG MD, MHS. Association of Pre-hospital Factors with Requiring Physical Therapist Intervention in Severe Penetrating Thoracic and Abdominal Trauma. Presented at: World Congress of Surgery. Basel, Switzerland. August 13-17, 2017.

2. Almuttawa A, Haut E, Velopulos CG. The role of prehospital factors in predicting mortality and functional outcomes for survivors. Presented at: World Congress of Surgery. Basel, Switzerland. August 13-17, 2017.

3. Callcut R, Kornblith L, Conroy A, Robles A, Meizoso J, Namias N, Meyer D, Haymaker A, Truitt M, Agrawal V, Haan J, Lightwine K, Porter J, San Roman J, Biffl W, Hayashi M, Sise M, Badiee J, Recinos G, Inaba K, Schroeppel T, Callaghan E, Dunn J, Godin S, McIntyre R, Peltz E, O’Neill P, Diven C, Scifres A, Cross A, West M, Storrs S, Cullinane D, Cordova J, Moore E, Moore H, Privette A, Eriksson E, and Cohen M. Abstract Title: The Why and How Our Trauma Patients Die: A Prospective Multicenter Western Trauma Association Study. Presented at: Western Trauma Association 48th Annual Meeting. Whistler, BC, Canada. February 25, 2018.

4. Carmichael H, Jamison E, Bol K, Velopulos CG. A Novel Area-Based Approach to Measuring Liquor Outlet Density and its Impact on Violence. Presented at: Alcohol and Immunology Research Interest Group. Denver, CO. January 2018.

5. Carmichael H, Jamison E, Bol K, Velopulos CG. Premeditated Versus Passionate: Patterns of Homicide Related to Intimate Partner Violence. Presented at: Academic Surgical Congress, Jacksonville, FL. January 30, 2018.

6. Carmichael, H. MD, Smith, T. MS, Wagner, A. M.D. MD FACS, Wiktor, A. MD FACS. Safety and Efficacy of Intraoperative Gastric Feeding During Burn Surgery. Presented at: American Burn Association Annual Conference. Chicago, IL. April 2018.

7. Frazee, R, Regner J, Truitt M, Agrawal V, Dirks R, Kwok A, Grover B, Kothari S, Scherer E, Chrane C, McIntyre Jr., R, Peltz E, Dissanaike S, Vangipuram D, Cribari C, Godin S, Gordy S, Bruns BR, O’Meara L, Schroeppel TJ, Callaghan E, Cothren Burlew C, Swope M. The Southwestern Surgical Congress Multi-Center Trial on Suspected Choledocholithiasis. Presented at: 70th Annual Meeting of the Southwestern Surgical Congress. Napa, CA. April 8-11, 2018.

8. Heelan-Gladden AA, McIntyre RC, Van Deventer KA, Krell R, Vega S, Bookman K, Peltz ED, Wright FL. Improving Outcomes in Hypotensive Trauma: Best Practices and Beyond. Presented at: International Forum on Quality and Safety in Healthcare. Amsterdam, Netherlands. May 2018.

Research Presentations

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9. Heelan-Gladden AA, Peltz ED, McIntyre RC, Vega S, Krell R, Velopulos C, Ferrigno L, Wright FL. The “ABC” Score and Thawed FFP Improves Resuscitation and Reduces Trauma Mortality. Presented at: Southwestern Surgical Congress. Napa, CA. April 8-11, 2018.

10. Heelan-Gladden AA, Vega S, McIntyre RC, Peltz ED, Wright FL. Activation of Massive Transfusion Protocols Utilizing the “ABC” Score and Immediate Availability of Thawed FFP Prior to Patient Arrival for Early Balanced Resuscitation Reduces Mortality Associated with Penetrating Trauma. Oral Presentation at: Colorado American College of Surgeons Committee on Trauma. Colorado Springs, CO. August 2017.

11. Kovacs, E. PhD. “Alcohol intoxication and the pulmonary inflammatory response after injury: Role of the gut – liver axis.” Presented at: Department of Cellular and Physiological Sciences. University of British Columbia, Vancouver, BC, Canada. October 2017.

12. Kovacs, E. PhD. “Alcohol intoxication exacerbates the pulmonary inflammatory response after injury: Role of the gut – liver axis.” Presented at: Department of Pathobiological Sciences, Louisiana State University, School of Veterinary Medicine. Baton Rouge, LA. November 2017.

13. Kovacs, E. PhD. “Inflamm-aging and the multi-organ system response to tissue injury.” Presented at: Innovations in Wound Healing. North Bimini Island, Bahamas. December 2017.

14. Kovacs, E. PhD. “Inflamm-aging and the pulmonary response to remote injury.” Presented at: Feinstein Institute for Medical Research. Manhasset, NY. November 2017.

15. Michel, S., Smith, T. MS, Wiktor, A. MD FACS, Wagner, A. M.D. MD FACS. “Implementation of a Remote Frostbite Protocol in the Use of Thrombolytic With Improved Salvage Rates.” Presented at: American Burn Association Annual Conference. Chicago, IL. April 2018.

16. Nunns GR, Banerjee A, Moore EE, Kelher M, D’Alessandro A, Burke T, Peltz E, Sauaia A, Silliman CC. “Post- Traumatic Acute Lung Injury: The Role of The Mitochondrial Metabolite Succinate.” Presented at: The American College of Surgeons Clinical Congress. San Diego, CA. October 22, 2017.

17. Nunns GR, Clendenen N, Moore HB, D'Alessandro A, Gonzalez E, Peltz E, Silliman CC, Fragoso M, Sauaia A, Banerjee A, Moore EE. Hemorrhagic Shock Drives the Plasma Metabolome in Trauma. Presented at: 12th Annual Academic Surgical Congress. Las Vegas, NV. February 8, 2017.

18. Smith MS, T., Wiktor, A. MD FACS, Lubie, D. DPT, Wagner, A. M.D. MD FACS. “Increasing Ambulation through Real-Time Feedback in Burn Patients.” Presented at: American Burn Association Annual Conference. Chicago, IL. April 2018.

19. Vega, S, McIntyre, R. Krell, R. Ferrigno, L. “Daily Surveillance PI Project Improves VTE Prophylaxis Compliance and Reduces Tracheostomy Times in Severe TBI Cohort.” Oral Abstract Presentation: 2017 TQIP Annual Scientific Meeting and Training, Chicago, IL. November 2017.

20. Wiktor, A. MD FACS, Wagner, A. M.D., MD, FACS. “Multi-Regional Utilization of a Mobile Device App for Triage and Transfer of Burn Patients.” Winner, Top 5 Abstract. Presented at: American Burn Association Annual Conference. Chicago, IL. April 2018.

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Dumond, R

Colorado Department of Health and Environment, State Emergency Medical and Trauma

Services, Positively Collaborative Award

Kovacs, E

Scientific Achievement Award, Shock Society, 2017 Recipient

McIntyre, RC Jr

5280 Magazine Best Doctor for both Surgical Critical Care and Surgery

Colorado Parent’s Magazine Top Doctors

Velopulos, CG

At-Risk Intervention and Mentoring (AIM) – Hospital-Based Violence Intervention Program,

Annual Award: $950,000; $750,000 for expansion, $200,000 for research/program evaluation,

dates of award 10/01/2018 – 09/30/2019

Wagner, AL

Extraordinary Service Award, Medical Staff, University of Colorado Hospital, 2017

Awards and Achievements

Page | 27

Dumond, R

American College of Surgeons, Trauma Quality Improvement Program (TQIP), Training Project Team, Program Manager Representative

Treasurer and Board of Directors, Colorado Trauma Network

American College of Surgeons, Trauma Systems Consultation Program, Program Manager Reviewer

Colorado American College of Surgeons Committee on Trauma Stop the Bleed Executive Committee, Outreach Chair

Colorado Department of Health, State Trauma Designation Site Reviewer

Ferrigno, L

Chair, American College of Surgeons Committee on Trauma, Colorado

Education Committee, American College of Surgeons Committee on Trauma, 2018

Research Committee, American College of Surgeons Committee on Trauma, 2018

Publications Committee, Western Trauma Association, 2017-2018

Multicenter Trials Committee, Western Trauma Association, 2018

Kovacs, E

President, Shock Society, 2018

President-Elect, Shock Society, 2017

Co-Chair, Radiation Research Society

Co-Chair, Program Committee, Alcohol and Immunity Research Interest Group (AIRIG)

Co-Chair, American Association of Immunologists (AAI)

Co-Chair, Society for Leukocyte Biology

McIntyre, RC Jr

Western Trauma Association, Vice President, 2018

Western Trauma Association, Treasurer, 2015-2018

Leadership Positions

Page | 28

Velopulos, CG

Association for Academic Surgery, Program Committee, Annual Meeting 2017 - Present

Eastern Association for the Surgery of Trauma, Program Committee, 2016 - Present

Vega, S

Colorado Trauma Network Performance Improvement and Registry Subcommittee, Chair

Colorado Department of Health, Continuous Quality Improvement Taskforce, Member, Trauma Program Representative

Colorado Department of Health, State Trauma Designation Site Reviewer

Wright, FL

Southwestern Surgical Congress, Budget and Finance Committee, 2015 - Present

Page | 29

ERIK PELTZ, DO

Dr. Anne Slaughter

T32 mentor 2014 - 2016 Education and supervision of investigational development (background research, hypothesis,

methods, data analysis, data interpretation) Presentations: mentorship and constructive review of poster and oral presentations for local and

national forums Mentorship of authoring/successful submission of scientific, peer reviewed publication Mentorship and co-authored Project Mu – Metabolomics for the P50 – “Trauma Primes Cells”

NIH grant renewal

Achievements of Mentee

3rd place, Earl Young paper competition, Western Trauma Association 2016 UCH, Ben Eiseman Basic Science Award – 2016 ACS Committee on Trauma, resident paper competition, Region 8 winner - 2016 Oral presentation, ASC 2016 Poster presentation, 38th Annual Conference on SHOCK, 2015 Oral presentation, SWSC 2015 Oral presentation, scientific forum, ACS, 2015 Co-author publication, Shock. 2016 1st author publication, JTACS. 2016 Co-author publication, Shock. 2015 1st author publication, Shock. 2015

Dr. Toni Bacon

T32 mentor 2014-2016

Achievements of Mentee

3 co-author peer reviewed publications Oral and poster presentations at national forums.

Dr. Alex Morton

T32 mentor 2015-2016

Achievements of Mentee

3 co-author peer reviewed publications Oral and poster presentations at national forums.

Student and Resident Mentorship

Page | 30

Dr. Peter Einersen

T32 mentor 2015 – present

Achievements of Mentee

1st author publication Development of advanced evaluation of TEG assessment with 2 manuscripts in

process/submission

Dr. Geoff Nunns

T32 mentor 2016 – present

Achievements of Mentee

Oral presentation, ASC 2017 Oral presentation, SWSC 2017

CATHERINE VELOPULOS, MD, MPH

1/2016 – Present: Surgical Outcomes and Applied Research (SOAR), CU-UNITE Urban Underserved Track | Capstone Mentor for Medical Students and Research Mentor for Resident. Billy Tran, CU Medical Student (Class of 2019)

Proposed Capstone (proposal submitted and accepted) – CU-UNITE student. Using ArcGIS for quantifying factors related to lived environment and Markov modeling for a cost-utility analysis of converting emergent general surgery to elective surgery through improved access to primary care and screening in the Park Hill Neighborhood. Sara Muramoto, CU Medical Student (Class of 2021)

At-Risk Intervention and Mentoring (AIM) Program – in conjunction with Katie Bakes, MD. Analysis of the intervention program through pre/post risk survey and structured interviews. 2017 EAST Templeton Injury Prevention Scholarship Finalist. Joshua Abolarin, CU Medical Student (Class of 2021)

Proposed Capstone – CU-UNITE student. Disparities topic TBD. Heather Carmichael, CU Surgical Resident

Using geographic information systems to link data to address surgical healthcare disparities and violence prevention. Analysis of the Colorado Violent Death Reporting System – Abstracts presented at the 2018 Academic Surgical Congress for Oral Presentation and 2018 Alcohol and Immunology Research Interest Group.

ELIZABETH KOVACS, PHD

Postdoctoral Fellows, Research Associates, Clinical Residents/Fellows, Research Assistant Professors. Anita Zahs, PhD, Postdoctoral Research Associate, Department of Surgery, 2016 (moved

with lab to the University of Colorado Denver) Lisbeth A. Boule, PhD, Research Postdoctoral Research Associate, Department of Surgery,

2016 - 2017 John Frankel, MD, Surgical Resident, Department of Surgery, 2017

Mentoring of Faculty Career Development Applicants and Awardees. Juan-Pablo Idrovo, MD, Assistant Professor of Surgery, Division of GI Trauma and Endocrine

Surgery, University of Colorado Denver, Aurora, CO, 2017 - Date

University of Colorado Hospital

12605 East 16th Avenue

Aurora, Colorado 80045

www.uchealth.org