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TRANING PERIOD INTRANING PERIOD IN

VISA DRUGS &VISA DRUGS &

PHARMACEUTICALS BADDI (HP)PHARMACEUTICALS BADDI (HP)

Presented by: Harwinder Kumar

Roll No. 81307421017

Address :-V.P.O Khera, pin code 146106,Dist Hoshiarpur.

Contacts - 01884242575, +919464065575.

Email Id:- harwinderpandit@yahoo.comharwinderpandit@hotmail.com

Collage:- RAYAT BAHRA INSTITUTE OF PHARMACY (Hoshiarpur, PUNJAB)Site:- http://home.rayatbahra.com/

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CONTENTSCONTENTS--

y 1. TABLET SECTION

y 2. CAPSULE SECTION

y 3. PACKAGING SECTION

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Instruments-

1. Paste kettle

2. RMG (Rapid Mixer Granulator)

3. FBD (Fluid Bed Dryer)

4. Vibro Sifter

5. Multimill

6. Blenders ( Double Cone Blender &octagonal blender)

7. Tablet Compression Machine

8. Tablet Coating Pan

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Working of CompressionWorking of Compression MMachineachine

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Problems during TabletProblems during Tablet CCompressionompression

y

CAPPING & LAMINATION-Capping

is defined as the splitting of one or both lidsof a tablet from its body. Lamination is similarto capping but here the tablet gets separatedinto layers.

y MOTTLING-Mottling is uneven distributionof the colour on the surface of the tablet,with dark and light patches on it.

y STICKING - It refers to the sticking of thetablet material with the die walls results inrough edges of tablet

y PICKING- Picking happens when a part ofthe tablets gets sticks to the punch surfaceand gets eroded from the tabletsurface.

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Capsule Filling & sealing Machine

Capsule Polishing Machine

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THE FIRSTSTATION:ORIENTATION OF

CAPSULE

The functions of first station

include capsule feeding,

aligning and insertion into boresof holding ring .

Also, vacuum is used for

separating capsule cap and body

in first station.

After orientation of capsule,capsule cap can stay in upper

holding ring and capsule body

can stay in lower holding ring.

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Separate the holding ring , put the lower (body) holding

ring on the rotary table, pull the powder hopper over the

lower (body) holding ring, then auger inside powder

hopper starts to run and fill powder into the capsule body.

While Iower holding ring turns one circle, push powderhopper to its original position.

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Put upper holding ring and lower holding ring together,

then take the holding ring ahead of ejector and aim

ejector at the bores of holding ring . Use hydraulic cylinder

to push ejector and let it press capsules for closing. Finally

push capsules inside the bores of holding ring out, thefinished capsules will be collected into the container.

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LOCKING If the empty shell capsules arelocked then they will not open into the holding

rings and powder filling does not occurs.

Denting Denting of cap or body is occur during

locking when locking is not properly occurred(due to increase in hydraulic pressure during

locking).

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In this packing one side of tablet stripes is PVC (Poly vinyl

Chloride) and another side is alumininum foil is used.

1.PVC FOILS- 1. PVC (Poly vinyl Chloride) foil 2.

PVDC(poly vinyl dichloride foil) foil.

Thickness of PVC foil 0.250mm.

2. ALUMINIUM FOIL

Thickness of aluminum foil 0.075mm.

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In which both side of tablet/capsule strips aluminium foil

is used.

Thickness of alu. Foil - 0.020mm to 0.045mm

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