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Identification and Validation of Drug Targets

i

IDENTIFICATION AND VALIDATION OF DRUG TARGETS FROM

BACTERIAL GENOMES

Thesis submitted to the

Bharathidasan University, Tiruchirappalli

for the award of the degree of

DOCTOR OF PHILOSOPHY IN MOLECULAR SYSTEMATICS

By

P. Paul Sharma Chakravarthy, M.Sc.

Ref: 32602 / Ph.D-1 / Molecular Systematics / FT / April 2006.

Under the guidance of

Dr. S. JOHN BRITTO, S. J.

The Rapinat Herbarium and

Centre for Molecular Systematics St. Joseph's College (Autonomous)

166 Years of Educational Excellence

Nationally Reaccredited with A+ Grade

College with Potential for Excellence

Tiruchirappalli - 620 002, India

SEPTEMBER