TIG SamplePrep Assay plate preparation 30039460 · Customized solutions from TIG (Tecan Integration...

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Customized solutions from TIG (Tecan Integration Group) Sample Preparation Compound Dilution and Assay Plate Preparation Inter-plate- and Intra-plate-Dilution of compounds for assay plate preparation and plate replication Technical Reference 30039460 Process Inter-plate Dilution 11 point dose response curves of 3872 compounds Intra-plate Dilution 11 point dose response curve of 640 compounds Plate Replication Seal peeling, control addition and 1:1 copy Input Inter-plate Dilution 11 DTBR384 filled with 352 compounds Intra-plate Dilution 20 DTBR384 filled with 32 compounds each Plate Replication 22 ECHO Source plates Output Inter-plate Dilution 121 Assay plates 384 (1 concen- tration per plate of 352 compounds) 44 ECHO Source plates 44 Intermediate plates In 7h 40min Intra-plate Dilution 20 Assay plates 384 (2x11 concen- trations per plate of 32 compounds) 10 ECHO Source plates 10 Intermediate plates In 3h Plate Replication 22 Assay plates In 2h 20min

Transcript of TIG SamplePrep Assay plate preparation 30039460 · Customized solutions from TIG (Tecan Integration...

Page 1: TIG SamplePrep Assay plate preparation 30039460 · Customized solutions from TIG (Tecan Integration Group) Manufactured by TIG (Tecan Integration Group), Tecan Schweiz AG, Seestrasse

Customized solutions from TIG (Tecan Integration Group)

Sample Preparation Compound Dilution and Assay Plate Preparation Inter-plate- and Intra-plate-Dilution of compounds for assay plate preparation and plate replication Technical Reference 30039460

Process Inter-plate Dilution 11 point dose response curves of 3872 compounds Intra-plate Dilution 11 point dose response curve of 640 compounds Plate Replication Seal peeling, control addition and 1:1 copy

Input Inter-plate Dilution 11 DTBR384 filled with 352 compounds Intra-plate Dilution 20 DTBR384 filled with 32 compounds each Plate Replication 22 ECHO Source plates

Output Inter-plate Dilution 121 Assay plates 384 (1 concen-tration per plate of 352 compounds) 44 ECHO Source plates 44 Intermediate plates In 7h 40min Intra-plate Dilution 20 Assay plates 384 (2x11 concen-trations per plate of 32 compounds) 10 ECHO Source plates 10 Intermediate plates In 3h Plate Replication 22 Assay plates In 2h 20min

Page 2: TIG SamplePrep Assay plate preparation 30039460 · Customized solutions from TIG (Tecan Integration Group) Manufactured by TIG (Tecan Integration Group), Tecan Schweiz AG, Seestrasse

Customized solutions from TIG (Tecan Integration Group)

Manufactured by TIG (Tecan Integration Group), Tecan Schweiz AG, Seestrasse 103, 8708 Männedorf Switzerland, www.tecan.com, p 2/9

System Overview Front view

# Type of module Brand, model 1. Automation platform Tecan Freedom EVO® 200 2. Liquid handler Tecan MultiChannel Arm™ 384 3. Plate piercer Velocity11 PlatePierce® 4. Plate sealer Velocity11 PlateLoc® 5. Plate seal remover Nexus Xpeel™ 6. Centrifuge Velocity11 VSpin® 7. Liquid handler Labcyte™ ECHO® 555 8. Adhesive sealer Micronix Autosealer PS-2001

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Page 3: TIG SamplePrep Assay plate preparation 30039460 · Customized solutions from TIG (Tecan Integration Group) Manufactured by TIG (Tecan Integration Group), Tecan Schweiz AG, Seestrasse

Customized solutions from TIG (Tecan Integration Group)

Manufactured by TIG (Tecan Integration Group), Tecan Schweiz AG, Seestrasse 103, 8708 Männedorf Switzerland, www.tecan.com, p 3/9

Back view

# Type of module Brand, model 1. Adhesive sealer Micronix Autosealer PS-2001 2. Liquid handler Tecan Freedom EVO® 200 3. Customized refill trough Peri Pump for refill troughs 4. Plate storage Tecan Autoloader™ 5. Plate storage Liconic LPX440 Carousel

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Page 4: TIG SamplePrep Assay plate preparation 30039460 · Customized solutions from TIG (Tecan Integration Group) Manufactured by TIG (Tecan Integration Group), Tecan Schweiz AG, Seestrasse

Customized solutions from TIG (Tecan Integration Group)

Manufactured by TIG (Tecan Integration Group), Tecan Schweiz AG, Seestrasse 103, 8708 Männedorf Switzerland, www.tecan.com, p 4/9

Top view of left side

1. Robotic Arm ROMA 2. Liquid handler Labcyte™ ECHO® 555 3. Plate seal remover Nexus Xpeel™ 4. Plate piercer Velocity11 PlatePierce® 5. Plate sealer Velocity11 PlateLoc® 6. Plate storage Transfer slide of Liconic LPX440 Carousel 7. Centrifuge Velocity11 VSpin®, integration below the worktable

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Page 5: TIG SamplePrep Assay plate preparation 30039460 · Customized solutions from TIG (Tecan Integration Group) Manufactured by TIG (Tecan Integration Group), Tecan Schweiz AG, Seestrasse

Customized solutions from TIG (Tecan Integration Group)

Manufactured by TIG (Tecan Integration Group), Tecan Schweiz AG, Seestrasse 103, 8708 Männedorf Switzerland, www.tecan.com, p 5/9

Highlights: TIG parts Refill trough for MCA 384 MCA384 pipettes with one DiTi row out of the refill trough

Column-wise intra-plate serial dilution with MCA384

Page 6: TIG SamplePrep Assay plate preparation 30039460 · Customized solutions from TIG (Tecan Integration Group) Manufactured by TIG (Tecan Integration Group), Tecan Schweiz AG, Seestrasse

Customized solutions from TIG (Tecan Integration Group)

Manufactured by TIG (Tecan Integration Group), Tecan Schweiz AG, Seestrasse 103, 8708 Männedorf Switzerland, www.tecan.com, p 6/9

Downholder carrier for REMP DTBR384

Page 7: TIG SamplePrep Assay plate preparation 30039460 · Customized solutions from TIG (Tecan Integration Group) Manufactured by TIG (Tecan Integration Group), Tecan Schweiz AG, Seestrasse

Customized solutions from TIG (Tecan Integration Group)

Manufactured by TIG (Tecan Integration Group), Tecan Schweiz AG, Seestrasse 103, 8708 Männedorf Switzerland, www.tecan.com, p 7/9

Highlights: 3rd party device integration Very compact integration of 3rd party devices

Integration of Micronix PS-2001 adhesive sealer Integration of ECHO 555 accustic liquid handler

Page 8: TIG SamplePrep Assay plate preparation 30039460 · Customized solutions from TIG (Tecan Integration Group) Manufactured by TIG (Tecan Integration Group), Tecan Schweiz AG, Seestrasse

Customized solutions from TIG (Tecan Integration Group)

Manufactured by TIG (Tecan Integration Group), Tecan Schweiz AG, Seestrasse 103, 8708 Männedorf Switzerland, www.tecan.com, p 8/9

VSpin integration below Freedom EVO

V11 PlatePierce used for piercing of REMP DTBR384 and V11 PlateLoc heat sealer integration

Page 9: TIG SamplePrep Assay plate preparation 30039460 · Customized solutions from TIG (Tecan Integration Group) Manufactured by TIG (Tecan Integration Group), Tecan Schweiz AG, Seestrasse

Customized solutions from TIG (Tecan Integration Group)

Manufactured by TIG (Tecan Integration Group), Tecan Schweiz AG, Seestrasse 103, 8708 Männedorf Switzerland, www.tecan.com, p 9/9

Transfer Slide of integrated Liconic Carousel

Scientific instrumentation; not for use in human, clinical or diagnostic procedure. All systems or products are tailor-made one-offs that were exclusively developed on customer demand. All displayed pictures and images originate from development-, test- or installation phases and do not claim to represent the final installation at customer site. Tecan and Freedom EVO are in major countries registered trademarks and MultiChannel Arm 384, Power Washer 384 are trademarks of Tecan Group Ltd., Männedorf, Switzerland. Storex is a registered trademark of Liconic AG, Mauren, Liechtenstein. Velocity11, PlatePierce, PlateLoc and VSpin are trademarks of Velocity11 Corp., Menlo Park, USA. ECHO is a trademark of Labcyte Inc., Sunnyvale, USA. Nexus Biosystems and Xpee are trademarks of Nexus Biosystems Inc., Poway, USA. © 2010, Tecan Trading AG, Switzerland, all rights reserved.