Three-component coupling reactions in ionic liquids: a facile synthesis of a-aminonitriles New J....

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Transcript of Three-component coupling reactions in ionic liquids: a facile synthesis of a-aminonitriles New J....

Page 1: Three-component coupling reactions in ionic liquids: a facile synthesis of a-aminonitriles New J. Chem., 2003, 27, 462–465.
Page 2: Three-component coupling reactions in ionic liquids: a facile synthesis of a-aminonitriles New J. Chem., 2003, 27, 462–465.

Three-component coupling reactions in ionic liquids: a facile synthesis of a-aminonitriles

New J. Chem., 2003, 27, 462–465

Page 3: Three-component coupling reactions in ionic liquids: a facile synthesis of a-aminonitriles New J. Chem., 2003, 27, 462–465.

Recycle 6 times without any apparent loss of activity

Page 4: Three-component coupling reactions in ionic liquids: a facile synthesis of a-aminonitriles New J. Chem., 2003, 27, 462–465.

Montmorillonite KSF clay catalyzed one-pot synthesis of a-aminonitriles

Tetrahedron 60 (2004) 1767–1771

Page 5: Three-component coupling reactions in ionic liquids: a facile synthesis of a-aminonitriles New J. Chem., 2003, 27, 462–465.

solid acids recycle 1. 92 %2. 87 %3. 82 %

Page 6: Three-component coupling reactions in ionic liquids: a facile synthesis of a-aminonitriles New J. Chem., 2003, 27, 462–465.

Nickel(II) chloride catalyzed one-pot synthesis of -aminonitriles

Journal of Molecular Catalysis A: Chemical 225 (2005) 169–171

Page 7: Three-component coupling reactions in ionic liquids: a facile synthesis of a-aminonitriles New J. Chem., 2003, 27, 462–465.
Page 8: Three-component coupling reactions in ionic liquids: a facile synthesis of a-aminonitriles New J. Chem., 2003, 27, 462–465.
Page 9: Three-component coupling reactions in ionic liquids: a facile synthesis of a-aminonitriles New J. Chem., 2003, 27, 462–465.

Gallium (III) triflate catalyzed efficient Streckerreaction of ketones and their fluorinated analogs

PNAS March 6, 2007 vol. 104 no. 10

Page 10: Three-component coupling reactions in ionic liquids: a facile synthesis of a-aminonitriles New J. Chem., 2003, 27, 462–465.
Page 11: Three-component coupling reactions in ionic liquids: a facile synthesis of a-aminonitriles New J. Chem., 2003, 27, 462–465.
Page 12: Three-component coupling reactions in ionic liquids: a facile synthesis of a-aminonitriles New J. Chem., 2003, 27, 462–465.

Fe(Cp)2PF6 catalyzed efficient Strecker reactions of ketones and aldehydes under solvent-free conditions

Tetrahedron Letters 49 (2008) 640–644

Page 13: Three-component coupling reactions in ionic liquids: a facile synthesis of a-aminonitriles New J. Chem., 2003, 27, 462–465.

1 : 1 : 1.3

Page 14: Three-component coupling reactions in ionic liquids: a facile synthesis of a-aminonitriles New J. Chem., 2003, 27, 462–465.