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Skin Pigmentation

Melanin in the Melanocyte Cells

Eumelanin Black/Brown Pigment

Pheomelanin Red/Yellow Pigment

Response to UV Radiation

Pigmented Cells

Resistant to amage !y Sun

Protected "rom Melanin #ntio$idants

Unpigmented Cells

Sensiti%e to Sunlight amage

Protected !y &lutathione/Selenomethionine

 #ntio$idants

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EP'&ME()#)'*( Properties o+

&lutathione/Selenium

, Protect Skin +rom UV Radiation which generate +ree

radicals that cause skin damage and hyperpigmentation

, &S- redirects synthesis to the light .Pheomelanin instead

o+ the dark .Eumelanin

, 'nhi!its en0yme tyrosinase that synthesi0es dark melanins

, Skin Cell1s !ecome more resistant to UV e$posure

 .Brigarti2 3445

  .Burke2 6778

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Skin Brightening

)hione Comple$9 lo0enges with:

&lutathione ; Selenomethionine

Plus #ntio$idant Vitamins C ; E

 #nd the &lutathione epigmenting En0ymes

 # complement to the Skin Brightening Products

"ree Radical Sca%enging "unctions to Reduce UV

Radiation to the Skin

<orks "rom <ithin )o )he Skin=

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Melasma

Blotchy -yper>pigmentation o+ "ace

 #ssociated with Pregnancy

)opical )herapy

-ydro?uinone2 Retinoic #cid

)hione Comple$9

*ral )herapy with &lutathione/Selenium

Reduces UV Radiation 'mpact on #++ected Skin

'nduces &lutathione En0ymes

Promotes Synthesis o+ Clear Melanin

'nhi!its )yrosinase En0yme that Makes ark Melanin

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)he #ging Skin

Chrono>aging Sagging Skin

Photo>aging

<rinkles and Pigmented @esions Ultra%iolet Radiation

 #cute: Sun!urn

Chronic: *$idati%e amage

Pre>malignant @esions.Aeratosis2 Moles

MalignancyS?uamous/Basal Cells

Malignant Melanoma

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'n+luence o+ &lutathione @e%els in 

Melanin Synthesis

Pathways to Melanin Synthesis

  -igh &S- @ow &S-

 

Eumelanin Eumelanin

  .ark Pigment .ark Pigment

Conclusion:

-igh &S- le%els in+luence pathway toward the production o+ greateramounts o+ clear pigment .Pheomelanin in skin cells