687

" XBD=141 XHG=102 YBD=248 YHG=212>is, " XBD=264 XHG=171 YBD=241 YHG=210>from " XBD=435 XHG=295 YBD=249 YHG=211>rinsing " XBD=615 XHG=467 YBD=240 YHG=212>waters. " XBD=699 XHG=665 YBD=239 YHG=209>A " XBD=929 XHG=732 YBD=248 YHG=209>suggested " XBD=1113 XHG=961 YBD=246 YHG=208>remedy " XBD=1176 XHG=1146 YBD=239 YHG=209>is " XBD=1274 XHG=1208 YBD=239 YHG=209>the" XBD=263 XHG=103 YBD=287 YHG=254>addition " XBD=322 XHG=284 YBD=283 YHG=254>of " XBD=507 XHG=343 YBD=284 YHG=253>chlorine " XBD=569 XHG=529 YBD=282 YHG=254>to " XBD=656 XHG=592 YBD=282 YHG=252>the " XBD=775 XHG=677 YBD=282 YHG=253>rinse " XBD=954 XHG=795 YBD=288 YHG=253>waters ; this " XBD=1117 XHG=1086 YBD=281 YHG=252>is " XBD=1273 XHG=1138 YBD=290 YHG=251>widely" XBD=187 XHG=104 YBD=330 YHG=298>used " XBD=244 XHG=207 YBD=327 YHG=297>in " XBD=330 XHG=266 YBD=327 YHG=296>the " XBD=496 XHG=353 YBD=326 YHG=296>United " XBD=656 XHG=519 YBD=329 YHG=295>States, " XBD=750 XHG=681 YBD=324 YHG=295>but " XBD=839 XHG=773 YBD=323 YHG=295>not " XBD=1043 XHG=860 YBD=324 YHG=294>favoured " XBD=1116 XHG=1065 YBD=332 YHG=294>by " XBD=1273 XHG=1142 YBD=324 YHG=294>Hobbs" XBD=171 XHG=103 YBD=374 YHG=341>and " XBD=343 XHG=192 YBD=371 YHG=339>Wilson. " XBD=473 XHG=394 YBD=368 YHG=339>The " XBD=647 XHG=491 YBD=368 YHG=337>method " XBD=757 XHG=665 YBD=375 YHG=338>they " XBD=959 XHG=775 YBD=367 YHG=336>advocate " XBD=1005 XHG=975 YBD=367 YHG=337>is " XBD=1089 XHG=1022 YBD=366 YHG=336>the " XBD=1274 XHG=1105 YBD=367 YHG=337>removal" XBD=137 XHG=103 YBD=416 YHG=386>of " XBD=229 XHG=167 YBD=414 YHG=383>the " XBD=457 XHG=262 YBD=420 YHG=382>detergent " XBD=537 XHG=484 YBD=420 YHG=381>by " XBD=661 XHG=563 YBD=410 YHG=381>rinse " XBD=822 XHG=687 YBD=410 YHG=381>waters " XBD=890 XHG=850 YBD=409 YHG=381>at " XBD=981 XHG=917 YBD=409 YHG=381>too " XBD=1098 XHG=1007 YBD=418 YHG=380>high " XBD=1149 XHG=1128 YBD=408 YHG=388>a " XBD=1270 XHG=1177 YBD=409 YHG=381>tem-" XBD=266 XHG=103 YBD=469 YHG=428>perature " XBD=345 XHG=287 YBD=456 YHG=426>for " XBD=548 XHG=366 YBD=454 YHG=424>bacterial " XBD=725 XHG=566 YBD=461 YHG=424>growth, " XBD=822 XHG=748 YBD=452 YHG=422>and " XBD=988 XHG=844 YBD=461 YHG=423>cooling " XBD=1046 XHG=1008 YBD=452 YHG=423>of " XBD=1132 XHG=1067 YBD=453 YHG=423>the " XBD=1274 XHG=1152 YBD=452 YHG=422>bottle" XBD=148 XHG=103 YBD=512 YHG=473>by " XBD=344 XHG=180 YBD=500 YHG=469>external " XBD=486 XHG=369 YBD=498 YHG=468>rinses " XBD=605 XHG=512 YBD=497 YHG=467>with " XBD=874 XHG=629 YBD=497 YHG=466>recirculated " XBD=1014 XHG=898 YBD=496 YHG=467>water " XBD=1081 XHG=1041 YBD=496 YHG=468>at " XBD=1272 XHG=1105 YBD=505 YHG=474>progres-" XBD=212 XHG=101 YBD=553 YHG=515>sively " XBD=458 XHG=244 YBD=549 YHG=511>decreasing " XBD=780 XHG=493 YBD=549 YHG=511>temperatures, " XBD=986 XHG=813 YBD=541 YHG=509>followed " XBD=1080 XHG=1028 YBD=549 YHG=510>by " XBD=1144 XHG=1122 YBD=540 YHG=519>a " XBD=1276 XHG=1185 YBD=540 YHG=510>final" XBD=254 XHG=101 YBD=591 YHG=557>internal " XBD=348 XHG=273 YBD=586 YHG=555>and " XBD=541 XHG=368 YBD=585 YHG=554>external " XBD=659 XHG=559 YBD=584 YHG=554>rinse " XBD=771 XHG=678 YBD=584 YHG=554>with " XBD=875 XHG=792 YBD=584 YHG=553>cold " XBD=1013 XHG=896 YBD=584 YHG=555>water " XBD=1151 XHG=1033 YBD=584 YHG=553>direct " XBD=1274 XHG=1175 YBD=584 YHG=554>from" XBD=161 XHG=99 YBD=633 YHG=602>the " XBD=295 XHG=185 YBD=631 YHG=600>main. " XBD=424 XHG=346 YBD=628 YHG=598>The " XBD=515 XHG=448 YBD=628 YHG=607>use " XBD=584 XHG=545 YBD=627 YHG=597>of " XBD=760 XHG=617 YBD=628 YHG=598>caustic " XBD=880 XHG=789 YBD=628 YHG=597>soda " XBD=945 XHG=905 YBD=627 YHG=606>as " XBD=992 XHG=970 YBD=627 YHG=606>a " XBD=1214 XHG=1020 YBD=637 YHG=597>detergent " XBD=1275 XHG=1244 YBD=628 YHG=597>is" XBD=230 XHG=100 YBD=676 YHG=645>almost " XBD=465 XHG=278 YBD=677 YHG=641>essential, " XBD=587 XHG=516 YBD=671 YHG=641>but " XBD=728 XHG=636 YBD=672 YHG=640>such " XBD=996 XHG=778 YBD=672 YHG=640>substances " XBD=1079 XHG=1038 YBD=672 YHG=650>as " XBD=1275 XHG=1128 YBD=672 YHG=641>sodium" XBD=351 XHG=102 YBD=722 YHG=686>metasilicate, " XBD=600 XHG=384 YBD=724 YHG=684>phosphate " XBD=712 XHG=636 YBD=715 YHG=684>and " XBD=947 XHG=743 YBD=716 YHG=684>carbonate " XBD=1050 XHG=979 YBD=715 YHG=694>can " XBD=1124 XHG=1076 YBD=716 YHG=685>be " XBD=1276 XHG=1152 YBD=716 YHG=684>added" XBD=186 XHG=99 YBD=762 YHG=730>with " XBD=438 XHG=224 YBD=767 YHG=730>advantage " XBD=519 XHG=478 YBD=759 YHG=730>to " XBD=725 XHG=560 YBD=759 YHG=728>increase " XBD=931 XHG=764 YBD=768 YHG=728>wetting, " XBD=1161 XHG=973 YBD=768 YHG=728>softening " XBD=1277 XHG=1201 YBD=759 YHG=729>and" XBD=389 XHG=99 YBD=811 YHG=772>deflocculating, " XBD=563 XHG=415 YBD=811 YHG=771>though " XBD=680 XHG=587 YBD=811 YHG=771>they " XBD=846 XHG=707 YBD=804 YHG=773>cannot " XBD=1016 XHG=869 YBD=811 YHG=772>replace " XBD=1106 XHG=1041 YBD=803 YHG=772>the " XBD=1277 XHG=1134 YBD=804 YHG=773>caustic" XBD=197 XHG=99 YBD=848 YHG=817>soda. " XBD=381 XHG=250 YBD=846 YHG=815>Hobbs " XBD=493 XHG=416 YBD=846 YHG=815>and " XBD=672 XHG=527 YBD=847 YHG=815>Wilson " XBD=839 XHG=703 YBD=846 YHG=816>favour " XBD=937 XHG=872 YBD=847 YHG=816>the " XBD=1277 XHG=971 YBD=847 YHG=815>narrow-necked" XBD=186 XHG=100 YBD=891 YHG=860>milk " XBD=324 XHG=205 YBD=890 YHG=859>bottle " XBD=436 XHG=342 YBD=889 YHG=859>with " XBD=478 XHG=456 YBD=889 YHG=867>a " XBD=668 XHG=496 YBD=898 YHG=867>press-on " XBD=803 XHG=689 YBD=890 YHG=859>metal " XBD=891 XHG=823 YBD=899 YHG=869>cap " XBD=988 XHG=913 YBD=890 YHG=859>and " XBD=1193 XHG=1007 YBD=891 YHG=859>condemn " XBD=1277 XHG=1211 YBD=890 YHG=860>the" XBD=386 XHG=99 YBD=934 YHG=902>wide-mouthed " XBD=542 XHG=418 YBD=933 YHG=902>bottle " XBD=665 XHG=572 YBD=934 YHG=903>with " XBD=856 XHG=696 YBD=942 YHG=903>press-in " XBD=1002 XHG=889 YBD=934 YHG=902>disks. " XBD=1133 XHG=1054 YBD=934 YHG=903>The " XBD=1279 XHG=1163 YBD=934 YHG=903>latter" XBD=192 XHG=99 YBD=978 YHG=948>have " XBD=316 XHG=222 YBD=977 YHG=947>been " XBD=468 XHG=347 YBD=977 YHG=946>found " XBD=731 XHG=500 YBD=986 YHG=947>responsible " XBD=821 XHG=762 YBD=977 YHG=947>for " XBD=969 XHG=854 YBD=987 YHG=956>many " XBD=1207 XHG=1002 YBD=978 YHG=946>outbreaks " XBD=1279 XHG=1239 YBD=977 YHG=947>of" XBD=344 XHG=96 YBD=1030 YHG=990>paratyphoid " XBD=436 XHG=360 YBD=1021 YHG=989>and " XBD=615 XHG=451 YBD=1029 YHG=990>typhoid " XBD=669 XHG=629 YBD=1021 YHG=991>in " XBD=856 XHG=683 YBD=1022 YHG=990>America " XBD=947 XHG=871 YBD=1021 YHG=991>and " XBD=1068 XHG=962 YBD=1022 YHG=991>there " XBD=1113 XHG=1082 YBD=1022 YHG=991>is " XBD=1278 XHG=1129 YBD=1030 YHG=990>general" XBD=305 XHG=99 YBD=1072 YHG=1035>agreement " XBD=424 XHG=336 YBD=1064 YHG=1033>that " XBD=549 XHG=456 YBD=1072 YHG=1033>they " XBD=715 XHG=580 YBD=1064 YHG=1034>should " XBD=793 XHG=746 YBD=1064 YHG=1034>be " XBD=1019 XHG=825 YBD=1066 YHG=1034>discarded " XBD=1091 XHG=1051 YBD=1065 YHG=1043>as |>" XBD=1277 XHG=1124 YBD=1073 YHG=1034>quickly" XBD=136 XHG=98 YBD=1106 YHG=1085>as " XBD=444 XHG=158 YBD=1107 YHG=1076>circumstances " XBD=617 XHG=465 YBD=1116 YHG=1078>permit.

SULPHAPYRAZINE

" XBD=225 XHG=142 YBD=1228 YHG=1197>THE " XBD=403 XHG=240 YBD=1238 YHG=1199>possible " XBD=602 XHG=419 YBD=1230 YHG=1198>chemical " XBD=893 XHG=618 YBD=1231 YHG=1199>modifications " XBD=948 XHG=910 YBD=1230 YHG=1200>of " XBD=1277 XHG=963 YBD=1239 YHG=1200>sulphanilamide" XBD=156 XHG=97 YBD=1272 YHG=1250>are " XBD=433 XHG=192 YBD=1279 YHG=1242>numberless, " XBD=549 XHG=473 YBD=1274 YHG=1243>and " XBD=643 XHG=586 YBD=1274 YHG=1244>for " XBD=823 XHG=681 YBD=1274 YHG=1244>several " XBD=968 XHG=860 YBD=1283 YHG=1253>years " XBD=1071 XHG=1004 YBD=1274 YHG=1244>the " XBD=1278 XHG=1106 YBD=1275 YHG=1244>research" XBD=335 XHG=97 YBD=1317 YHG=1285>laboratories " XBD=408 XHG=369 YBD=1317 YHG=1287>of " XBD=750 XHG=443 YBD=1327 YHG=1287>manufacturing " XBD=886 XHG=783 YBD=1319 YHG=1288>firms " XBD=1016 XHG=919 YBD=1318 YHG=1289>have " XBD=1145 XHG=1051 YBD=1318 YHG=1288>been " XBD=1278 XHG=1179 YBD=1327 YHG=1288>busy" XBD=290 XHG=97 YBD=1369 YHG=1330>preparing " XBD=383 XHG=307 YBD=1361 YHG=1331>and " XBD=543 XHG=400 YBD=1371 YHG=1332>testing " XBD=642 XHG=560 YBD=1362 YHG=1341>new " XBD=892 XHG=659 YBD=1370 YHG=1332>compounds " XBD=948 XHG=911 YBD=1362 YHG=1332>of " XBD=1041 XHG=966 YBD=1362 YHG=1332>this " XBD=1163 XHG=1060 YBD=1371 YHG=1334>type. " XBD=1278 XHG=1199 YBD=1362 YHG=1332>The" XBD=192 XHG=99 YBD=1403 YHG=1375>most " XBD=412 XHG=210 YBD=1405 YHG=1375>successful " XBD=505 XHG=430 YBD=1405 YHG=1375>line " XBD=598 XHG=529 YBD=1406 YHG=1375>has " XBD=716 XHG=621 YBD=1405 YHG=1376>been " XBD=804 XHG=739 YBD=1406 YHG=1376>the " XBD=1004 XHG=824 YBD=1406 YHG=1376>insertion " XBD=1066 XHG=1027 YBD=1406 YHG=1376>of " XBD=1111 XHG=1089 YBD=1405 YHG=1385>a " XBD=1277 XHG=1131 YBD=1406 YHG=1376>hetero-

" XBD=208 XHG=97 YBD=1456 YHG=1417>cyclic " XBD=305 XHG=223 YBD=1458 YHG=1418>ring " XBD=401 XHG=320 YBD=1449 YHG=1419>into " XBD=485 XHG=419 YBD=1450 YHG=1419>the " XBD=789 XHG=502 YBD=1458 YHG=1419>sulphonamide " XBD=936 XHG=804 YBD=1459 YHG=1428>group, " XBD=1029 XHG=954 YBD=1450 YHG=1419>and " XBD=1084 XHG=1046 YBD=1449 YHG=1420>in " XBD=1176 XHG=1100 YBD=1449 YHG=1419>this " XBD=1278 XHG=1192 YBD=1458 YHG=1429>way" XBD=411 XHG=98 YBD=1501 YHG=1461>sulphapyridine, " XBD=777 XHG=466 YBD=1503 YHG=1463>sulphathiazole, " XBD=906 XHG=830 YBD=1494 YHG=1464>and " XBD=1059 XHG=957 YBD=1494 YHG=1473>more " XBD=1279 XHG=1109 YBD=1503 YHG=1463>recently" XBD=372 XHG=97 YBD=1545 YHG=1505>sulphadiazine " XBD=495 XHG=395 YBD=1538 YHG=1508>have " XBD=613 XHG=518 YBD=1538 YHG=1508>been " XBD=839 XHG=636 YBD=1546 YHG=1507>produced. " XBD=995 XHG=892 YBD=1538 YHG=1508>Each " XBD=1058 XHG=1019 YBD=1538 YHG=1507>of " XBD=1186 XHG=1080 YBD=1538 YHG=1507>these " XBD=1278 XHG=1209 YBD=1544 YHG=1507>has" XBD=142 XHG=97 YBD=1580 YHG=1549>its " XBD=246 XHG=165 YBD=1581 YHG=1559>own " XBD=505 XHG=270 YBD=1590 YHG=1551>advantages " XBD=606 XHG=529 YBD=1581 YHG=1551>and " XBD=922 XHG=628 YBD=1590 YHG=1551>disadvantages " XBD=1066 XHG=944 YBD=1582 YHG=1551>which " XBD=1223 XHG=1089 YBD=1581 YHG=1551>render " XBD=1277 XHG=1246 YBD=1581 YHG=1552>it" XBD=194 XHG=97 YBD=1624 YHG=1602>more " XBD=378 XHG=217 YBD=1625 YHG=1594>suitable " XBD=473 XHG=402 YBD=1625 YHG=1590>for " XBD=589 XHG=487 YBD=1625 YHG=1604>some " XBD=794 XHG=613 YBD=1634 YHG=1604>purposes " XBD=913 XHG=818 YBD=1625 YHG=1595>than " XBD=1077 XHG=938 YBD=1625 YHG=1595>others. " XBD=1277 XHG=1127 YBD=1634 YHG=1594>Among" XBD=157 XHG=96 YBD=1681 YHG=1637>the " XBD=294 XHG=182 YBD=1669 YHG=1638>latest " XBD=558 XHG=322 YBD=1678 YHG=1639>compounds " XBD=624 XHG=585 YBD=1669 YHG=1640>to " XBD=798 XHG=653 YBD=1678 YHG=1648>emerge " XBD=855 XHG=824 YBD=1669 YHG=1639>is " XBD=1209 XHG=883 YBD=1678 YHG=1638>sulphapyrazine, " XBD=1276 XHG=1237 YBD=1669 YHG=1639>in.

" XBD=903 XHG=570 YBD=1712 YHG=1683>-C-NH-CH .

" XBD=211 XHG=96 YBD=1747 YHG=1716>which " XBD=250 XHG=228 YBD=1747 YHG=1726>a " XBD=447 XHG=267 YBD=1757 YHG=1718>pyrazine " XBD=550 XHG=466 YBD=1757 YHG=1718>ring " XBD=643 XHG=631 YBD=1752 YHG=1723>11 " XBD=860 XHG=850 YBD=1754 YHG=1723>II " XBD=955 XHG=925 YBD=1748 YHG=1717>is " XBD=1140 XHG=975 YBD=1756 YHG=1718>present. " XBD=1277 XHG=1188 YBD=1748 YHG=1716>This" XBD=908 XHG=623 YBD=1789 YHG=1761>CH-NH-CH

" XBD=304 XHG=97 YBD=1839 YHG=1800>compound " XBD=387 XHG=318 YBD=1831 YHG=1801>has " XBD=498 XHG=403 YBD=1831 YHG=1801>been " XBD=606 XHG=513 YBD=1830 YHG=1800>used " XBD=819 XHG=621 YBD=1839 YHG=1800>especially " XBD=981 XHG=834 YBD=1839 YHG=1800>against " XBD=1275 XHG=995 YBD=1838 YHG=1800>pneumococci," XBD=168 XHG=97 YBD=1874 YHG=1843>and " XBD=332 XHG=187 YBD=1883 YHG=1846>reports " XBD=405 XHG=356 YBD=1874 YHG=1854>on " XBD=477 XHG=426 YBD=1874 YHG=1844>its " XBD=661 XHG=500 YBD=1883 YHG=1844>activity " XBD=721 XHG=682 YBD=1874 YHG=1844>in " XBD=885 XHG=742 YBD=1874 YHG=1844>human " XBD=983 XHG=907 YBD=1873 YHG=1843>and " XBD=1278 XHG=1005 YBD=1882 YHG=1843>experimental" XBD=288 XHG=97 YBD=1919 YHG=1887>infections " XBD=409 XHG=310 YBD=1918 YHG=1888>have " XBD=535 XHG=439 YBD=1918 YHG=1888>been " XBD=758 XHG=557 YBD=1926 YHG=1887>published " XBD=839 XHG=787 YBD=1927 YHG=1887>by " XBD=1097 XHG=864 YBD=1926 YHG=1887>Ruegsegger " XBD=1196 XHG=1120 YBD=1917 YHG=1887>and " XBD=1276 XHG=1218 YBD=1917 YHG=1887>his|>" XBD=324 XHG=74 YBD=1974 YHG=1932>colleagues.l " XBD=561 XHG=376 YBD=1970 YHG=1931>Recently " XBD=767 XHG=598 YBD=1962 YHG=1931>Schmidt " XBD=876 XHG=801 YBD=1962 YHG=1931>and Sesler " XBD=1192 XHG=1043 YBD=1975 YHG=1931>2 have " XBD=1283 XHG=1220 YBD=1962 YHG=1926>in-’" XBD=301 XHG=97 YBD=2016 YHG=1976>vestigated " XBD=371 XHG=321 YBD=2006 YHG=1976>its " XBD=522 XHG=393 YBD=2006 YHG=1976>action " XBD=691 XHG=543 YBD=2014 YHG=1975>against " XBD=983 XHG=712 YBD=2013 YHG=1975>experimental " XBD=1276 XHG=1004 YBD=2013 YHG=1971>streptococcal" XBD=298 XHG=96 YBD=2056 YHG=2020>infections, " XBD=420 XHG=344 YBD=2050 YHG=2019>and " XBD=561 XHG=462 YBD=2049 YHG=2019>have " XBD=787 XHG=607 YBD=2057 YHG=2018>analysed " XBD=895 XHG=829 YBD=2049 YHG=2019>the " XBD=1276 XHG=936 YBD=2057 YHG=2018>pharmacological" XBD=337 XHG=95 YBD=2104 YHG=2063>peculiarities " XBD=473 XHG=350 YBD=2094 YHG=2063>which " XBD=736 XHG=485 YBD=2093 YHG=2062>differentiate " XBD=780 XHG=749 YBD=2093 YHG=2062>it " XBD=890 XHG=792 YBD=2093 YHG=2061>from " XBD=970 XHG=906 YBD=2093 YHG=2062>the " XBD=1089 XHG=982 YBD=2093 YHG=2062>other " XBD=1274 XHG=1100 YBD=2093 YHG=2071>common" XBD=405 XHG=95 YBD=2148 YHG=2107>sulphonamides. " XBD=579 XHG=455 YBD=2138 YHG=2106>When " XBD=622 XHG=591 YBD=2137 YHG=2107>it " XBD=666 XHG=634 YBD=2138 YHG=2106>is " XBD=946 XHG=680 YBD=2137 YHG=2106>administered " XBD=1000 XHG=960 YBD=2136 YHG=2108>to " XBD=1109 XHG=1015 YBD=2137 YHG=2106>mice " XBD=1160 XHG=1122 YBD=2137 YHG=2106>in " XBD=1275 XHG=1174 YBD=2145 YHG=2106>large" XBD=266 XHG=95 YBD=2192 YHG=2152>repeated " XBD=407 XHG=287 YBD=2187 YHG=2151>doses, " XBD=480 XHG=429 YBD=2181 YHG=2151>its " XBD=672 XHG=501 YBD=2181 YHG=2151>curative " XBD=815 XHG=691 YBD=2190 YHG=2159>power " XBD=865 XHG=834 YBD=2181 YHG=2151>is " XBD=1004 XHG=886 YBD=2181 YHG=2150>about " XBD=1089 XHG=1024 YBD=2180 YHG=2150>the " XBD=1213 XHG=1111 YBD=2180 YHG=2160>same " XBD=1275 XHG=1233 YBD=2180 YHG=2159>as" XBD=174 XHG=94 YBD=2227 YHG=2197>that " XBD=230 XHG=193 YBD=2226 YHG=2196>of " XBD=360 XHG=247 YBD=2234 YHG=2195>equal " XBD=486 XHG=377 YBD=2225 YHG=2195>doses " XBD=544 XHG=505 YBD=2224 YHG=2194>of " XBD=886 XHG=561 YBD=2234 YHG=2194>sulphanilamide, " XBD=1215 XHG=906 YBD=2233 YHG=2194>sulphapyridine " XBD=1274 XHG=1233 YBD=2223 YHG=2203>or" XBD=397 XHG=94 YBD=2280 YHG=2239>sulphathiazole. " XBD=528 XHG=450 YBD=2268 YHG=2239>But " XBD=665 XHG=556 YBD=2268 YHG=2238>when " XBD=804 XHG=695 YBD=2269 YHG=2237>small " XBD=939 XHG=832 YBD=2268 YHG=2237>doses " XBD=1031 XHG=969 YBD=2267 YHG=2247>are " XBD=1153 XHG=1060 YBD=2268 YHG=2238>used " XBD=1212 XHG=1181 YBD=2268 YHG=2238>it " XBD=1273 XHG=1241 YBD=2268 YHG=2238>is" XBD=200 XHG=94 YBD=2315 YHG=2281>much " XBD=393 XHG=226 YBD=2321 YHG=2283>superior " XBD=460 XHG=418 YBD=2312 YHG=2283>to " XBD=596 XHG=488 YBD=2312 YHG=2282>them " XBD=672 XHG=620 YBD=2312 YHG=2280>all " XBD=831 XHG=697 YBD=2321 YHG=2283>except " XBD=1154 XHG=860 YBD=2320 YHG=2281>sulphadiazine, " XBD=1273 XHG=1179 YBD=2311 YHG=2281>with" XBD=207 XHG=92 YBD=2359 YHG=2328>which " XBD=251 XHG=221 YBD=2357 YHG=2328>it " XBD=296 XHG=265 YBD=2356 YHG=2327>is " XBD=430 XHG=311 YBD=2356 YHG=2326>about " XBD=568 XHG=445 YBD=2365 YHG=2325>equal. " XBD=652 XHG=619 YBD=2355 YHG=2325>A " XBD=783 XHG=665 YBD=2365 YHG=2325>study " XBD=835 XHG=797 YBD=2355 YHG=2325>of " XBD=914 XHG=848 YBD=2355 YHG=2325>the " XBD=1041 XHG=928 YBD=2355 YHG=2325>blood " XBD=1272 XHG=1055 YBD=2355 YHG=2327>concentra-" XBD=168 XHG=92 YBD=2401 YHG=2371>tion " XBD=247 XHG=200 YBD=2400 YHG=2380>on " XBD=455 XHG=279 YBD=2400 YHG=2370>different " XBD=595 XHG=488 YBD=2399 YHG=2369>doses " XBD=748 XHG=626 YBD=2399 YHG=2368>shows " XBD=866 XHG=780 YBD=2399 YHG=2368>that " XBD=928 XHG=897 YBD=2398 YHG=2368>it " XBD=989 XHG=958 YBD=2398 YHG=2368>is " XBD=1111 XHG=1022 YBD=2407 YHG=2368>only " XBD=1273 XHG=1143 YBD=2407 YHG=2368>slowly" XBD=271 XHG=92 YBD=2445 YHG=2412>absorbed " XBD=362 XHG=286 YBD=2443 YHG=2413>and " XBD=508 XHG=377 YBD=2451 YHG=2413>slowly " XBD=710 XHG=523 YBD=2443 YHG=2411>excreted. |>" XBD=1040 XHG=763 YBD=2451 YHG=2411>Consequently " XBD=1149 XHG=1055 YBD=2443 YHG=2421>even " XBD=1274 XHG=1164 YBD=2442 YHG=2411>small" XBD=194 XHG=93 YBD=2488 YHG=2457>doses " XBD=376 XHG=210 YBD=2495 YHG=2457>produce " XBD=416 XHG=394 YBD=2485 YHG=2465>a " XBD=547 XHG=434 YBD=2495 YHG=2456>fairly " XBD=653 XHG=563 YBD=2495 YHG=2455>high " XBD=747 XHG=672 YBD=2485 YHG=2455>and " XBD=968 XHG=764 YBD=2495 YHG=2455>prolonged " XBD=1272 XHG=987 YBD=2486 YHG=2456>concentration" XBD=128 XHG=93 YBD=2531 YHG=2501>in " XBD=216 XHG=151 YBD=2531 YHG=2501>the " XBD=367 XHG=240 YBD=2535 YHG=2500>blood, " XBD=471 XHG=394 YBD=2529 YHG=2499>and " XBD=545 XHG=496 YBD=2529 YHG=2508>an " XBD=735 XHG=570 YBD=2529 YHG=2500>increase " XBD=798 XHG=760 YBD=2529 YHG=2498>in " XBD=889 XHG=823 YBD=2529 YHG=2498>the " XBD=1003 XHG=916 YBD=2530 YHG=2489>dose " XBD=1158 XHG=1029 YBD=2530 YHG=2507>causes " XBD=1274 XHG=1184 YBD=2537 YHG=2499>only" XBD=112 XHG=92 YBD=2574 YHG=2553>a " XBD=237 XHG=130 YBD=2575 YHG=2543>small " XBD=327 XHG=255 YBD=2574 YHG=2544>rise " XBD=386 XHG=346 YBD=2574 YHG=2543>in " XBD=472 XHG=405 YBD=2575 YHG=2543>the " XBD=678 XHG=491 YBD=2574 YHG=2543>resultant " XBD=982 XHG=698 YBD=2574 YHG=2543>concentration " XBD=1046 XHG=1002 YBD=2573 YHG=2543>in " XBD=1126 XHG=1061 YBD=2576 YHG=2543>the " XBD=1271 XHG=1146 YBD=2574 YHG=2542>blood." XBD=203 XHG=91 YBD=2618 YHG=2587>These " XBD=440 XHG=230 YBD=2626 YHG=2587>properties " XBD=603 XHG=468 YBD=2617 YHG=2586>should " XBD=678 XHG=631 YBD=2617 YHG=2587>be " XBD=828 XHG=705 YBD=2617 YHG=2587>useful " XBD=893 XHG=854 YBD=2617 YHG=2587>in " XBD=1068 XHG=922 YBD=2617 YHG=2586>clinical " XBD=1272 XHG=1094 YBD=2626 YHG=2587>practice," XBD=185 XHG=91 YBD=2661 YHG=2630>since " XBD=280 XHG=209 YBD=2661 YHG=2631>less " XBD=481 XHG=304 YBD=2669 YHG=2631>frequent " XBD=615 XHG=507 YBD=2661 YHG=2630>doses " XBD=766 XHG=638 YBD=2661 YHG=2622>would " XBD=835 XHG=788 YBD=2660 YHG=2630>be " XBD=1015 XHG=859 YBD=2661 YHG=2630>needed. " XBD=1272 XHG=1066 YBD=2666 YHG=2630>Moreover," XBD=151 XHG=89 YBD=2704 YHG=2674>the " XBD=258 XHG=170 YBD=2704 YHG=2674>slow " XBD=500 XHG=278 YBD=2712 YHG=2673>absorption " XBD=644 XHG=519 YBD=2704 YHG=2673>would " XBD=756 XHG=664 YBD=2704 YHG=2673>offer " XBD=823 XHG=775 YBD=2704 YHG=2683>an " XBD=1055 XHG=843 YBD=2704 YHG=2673>additional " XBD=1273 XHG=1073 YBD=2714 YHG=2673>safeguard" XBD=231 XHG=89 YBD=2756 YHG=2717>against " XBD=366 XHG=262 YBD=2748 YHG=2717>toxic " XBD=528 XHG=397 YBD=2748 YHG=2717>effects " XBD=656 XHG=557 YBD=2747 YHG=2717>from " XBD=927 XHG=688 YBD=2757 YHG=2717>overdosage. " XBD=1037 XHG=981 YBD=2747 YHG=2717>On " XBD=1134 XHG=1068 YBD=2748 YHG=2718>the " XBD=1274 XHG=1165 YBD=2748 YHG=2717>other" XBD=199 XHG=88 YBD=2795 YHG=2758>hand, " XBD=251 XHG=222 YBD=2790 YHG=2760>if " XBD=296 XHG=273 YBD=2790 YHG=2770>a " XBD=409 XHG=316 YBD=2800 YHG=2760>high " XBD=547 XHG=432 YBD=2791 YHG=2760>blood " XBD=854 XHG=570 YBD=2791 YHG=2761>concentration " XBD=908 XHG=875 YBD=2792 YHG=2761>is " XBD=1103 XHG=930 YBD=2800 YHG=2761>required " XBD=1184 XHG=1125 YBD=2791 YHG=2761>for " XBD=1273 XHG=1207 YBD=2794 YHG=2761>the" XBD=291 XHG=88 YBD=2833 YHG=2803>treatment " XBD=348 XHG=309 YBD=2833 YHG=2804>of " XBD=388 XHG=366 YBD=2834 YHG=2813>a " XBD=535 XHG=406 YBD=2834 YHG=2813>severe " XBD=637 XHG=553 YBD=2834 YHG=2812>case " XBD=685 XHG=654 YBD=2835 YHG=2804>it " XBD=733 XHG=702 YBD=2834 YHG=2804>is " XBD=910 XHG=752 YBD=2836 YHG=2803>difficult " XBD=968 XHG=928 YBD=2834 YHG=2806>to " XBD=1119 XHG=987 YBD=2834 YHG=2804>obtain " XBD=1189 XHG=1137 YBD=2843 YHG=2805>by " XBD=1273 XHG=1207 YBD=2835 YHG=2804>the" XBD=163 XHG=88 YBD=2875 YHG=2845>oral " XBD=495 XHG=187 YBD=2877 YHG=2846>administration " XBD=559 XHG=521 YBD=2877 YHG=2847>of " XBD=910 XHG=584 YBD=2886 YHG=2847>sulphapyrazine, " XBD=1012 XHG=937 YBD=2878 YHG=2847>and " XBD=1068 XHG=1036 YBD=2878 YHG=2848>it " XBD=1123 XHG=1092 YBD=2878 YHG=2849>is " XBD=1273 XHG=1149 YBD=2877 YHG=2847>better" XBD=122 XHG=85 YBD=2917 YHG=2888>to " XBD=236 XHG=152 YBD=2927 YHG=2888>give " XBD=419 XHG=269 YBD=2920 YHG=2890>sodium " XBD=772 XHG=457 YBD=2929 YHG=2890>sulphapyrazine " XBD=859 XHG=807 YBD=2929 YHG=2891>by " XBD=1091 XHG=899 YBD=2929 YHG=2890>injection. " XBD=1272 XHG=1159 YBD=2921 YHG=2891>From" XBD=241 XHG=88 YBD=2961 YHG=2931>another " XBD=401 XHG=258 YBD=2971 YHG=2934>aspect, " XBD=486 XHG=420 YBD=2963 YHG=2932>the " XBD=594 XHG=502 YBD=2964 YHG=2933>slow " XBD=829 XHG=609 YBD=2973 YHG=2933>absorption " XBD=885 XHG=846 YBD=2964 YHG=2934>of " XBD=1216 XHG=902 YBD=2973 YHG=2934>sulphapyrazine " XBD=1272 XHG=1232 YBD=2964 YHG=2934>in" XBD=149 XHG=87 YBD=3003 YHG=2973>the " XBD=407 XHG=180 YBD=3014 YHG=2974>alimentary " XBD=550 XHG=438 YBD=3007 YHG=2976>canal " XBD=701 XHG=581 YBD=3016 YHG=2977>might " XBD=780 XHG=733 YBD=3007 YHG=2977>be " XBD=994 XHG=811 YBD=3016 YHG=2977>expected " XBD=1065 XHG=1025 YBD=3007 YHG=2979>to " XBD=1209 XHG=1098 YBD=3007 YHG=2977>make " XBD=1271 XHG=1240 YBD=3007 YHG=2977>it" XBD=204 XHG=86 YBD=3047 YHG=3016>useful " XBD=374 XHG=225 YBD=3058 YHG=3019>against " XBD=618 XHG=405 YBD=3058 YHG=3020>dysenteric " XBD=840 XHG=640 YBD=3051 YHG=3020>infections " XBD=902 XHG=864 YBD=3050 YHG=3020>of " XBD=995 XHG=930 YBD=3050 YHG=3020>the " XBD=1129 XHG=1017 YBD=3051 YHG=3020>lower " XBD=1271 XHG=1151 YBD=3052 YHG=3020>bowel" XBD=124 XHG=86 YBD=3089 YHG=3066>as " XBD=169 XHG=146 YBD=3089 YHG=3068>a " XBD=400 XHG=192 YBD=3092 YHG=3061>substitute " XBD=483 XHG=422 YBD=3092 YHG=3063>for " XBD=857 XHG=506 YBD=3102 YHG=3062>sulphaguanidine. |>" XBD=1035 XHG=884 YBD=3094 YHG=3062>I’SThite has " XBD=1271 XHG=1149 YBD=3092 YHG=3063>found" XBD=397 XHG=87 YBD=3143 YHG=3101>sulphapyrazine " XBD=508 XHG=414 YBD=3143 YHG=3114>very " XBD=699 XHG=527 YBD=3136 YHG=3105>effective " XBD=756 XHG=716 YBD=3136 YHG=3106>in " XBD=952 XHG=774 YBD=3145 YHG=3106>reducing " XBD=1035 XHG=970 YBD=3136 YHG=3106>the " XBD=1212 XHG=1053 YBD=3137 YHG=3106>number " XBD=1271 XHG=1231 YBD=3136 YHG=3106>of" XBD=250 XHG=86 YBD=3177 YHG=3145>coliform " XBD=471 XHG=262 YBD=3187 YHG=3148>organisms " XBD=523 XHG=483 YBD=3178 YHG=3148>in " XBD=600 XHG=534 YBD=3179 YHG=3148>the " XBD=809 XHG=611 YBD=3180 YHG=3149>intestines " XBD=860 XHG=822 YBD=3180 YHG=3150>of " XBD=984 XHG=878 YBD=3185 YHG=3150>mice, " XBD=1068 XHG=998 YBD=3179 YHG=3150>but " XBD=1270 XHG=1081 YBD=3190 YHG=3149>adequate" XBD=223 XHG=87 YBD=3220 YHG=3189>studies " XBD=290 XHG=241 YBD=3221 YHG=3200>on " XBD=476 XHG=305 YBD=3230 YHG=3191>patients " XBD=585 XHG=491 YBD=3222 YHG=3191>with " XBD=806 XHG=602 YBD=3231 YHG=3192>dysentery " XBD=886 XHG=822 YBD=3223 YHG=3202>are " XBD=969 XHG=903 YBD=3223 YHG=3194>not " XBD=1052 XHG=986 YBD=3231 YHG=3194>yet " XBD=1267 XHG=1069 YBD=3222 YHG=3192>available." XBD=134 XHG=86 YBD=3262 YHG=3230>To " XBD=242 XHG=160 YBD=3263 YHG=3241>sum " XBD=332 XHG=266 YBD=3273 YHG=3243>up, " XBD=676 XHG=357 YBD=3274 YHG=3235>sulphapyrazine " XBD=898 XHG=698 YBD=3266 YHG=3235>resembles " XBD=1205 XHG=923 YBD=3273 YHG=3235>sulphadiazine " XBD=1269 XHG=1228 YBD=3265 YHG=3235>in" XBD=195 XHG=85 YBD=3314 YHG=3282>many " XBD=322 XHG=207 YBD=3315 YHG=3286>ways, " XBD=418 XHG=342 YBD=3308 YHG=3278>and " XBD=527 XHG=437 YBD=3316 YHG=3287>may " XBD=712 XHG=544 YBD=3316 YHG=3277>possibly " XBD=776 XHG=729 YBD=3308 YHG=3278>be " XBD=881 XHG=789 YBD=3308 YHG=3278>used " XBD=1048 XHG=898 YBD=3309 YHG=3278>instead " XBD=1099 XHG=1061 YBD=3307 YHG=3278>of " XBD=1268 XHG=1117 YBD=3315 YHG=3277>sulpha-

1. Ruegsegger, J. M., Hamburger, M. jun. et al. Amer. J. med. Sci.1941, 202, 432.

2. Schmidt, L. H. and Sesler, C. L. J. Pharmacol. 1943, 77, 277.3. White, H. S. Bull. Johns Hopk. Hosp. 1942, 71, 213.

" XBD=1547 XHG=1336 YBD=247 YHG=208>guanidine " XBD=1722 XHG=1573 YBD=247 YHG=208>against " XBD=1959 XHG=1743 YBD=246 YHG=207>dysentery, " XBD=2053 XHG=1983 YBD=237 YHG=206>but " XBD=2106 XHG=2075 YBD=237 YHG=207>it " XBD=2289 XHG=2126 YBD=238 YHG=207>remains " XBD=2353 XHG=2312 YBD=237 YHG=208>to " XBD=2424 XHG=2377 YBD=237 YHG=206>be " XBD=2532 XHG=2445 YBD=238 YHG=215>seen" XBD=1509 XHG=1338 YBD=282 YHG=251>whether " XBD=1556 XHG=1526 YBD=281 YHG=252>it " XBD=1643 XHG=1573 YBD=281 YHG=252>has " XBD=1737 XHG=1662 YBD=290 YHG=260>any " XBD=1973 XHG=1757 YBD=290 YHG=251>advantage " XBD=2080 XHG=1991 YBD=281 YHG=260>over " XBD=2204 XHG=2098 YBD=281 YHG=250>these " XBD=2471 XHG=2223 YBD=290 YHG=250>compounds.

THERAPEUTICS MADE EASIER

" XBD=1428 XHG=1387 YBD=393 YHG=364>IT " XBD=1491 XHG=1460 YBD=394 YHG=364>is " XBD=1773 XHG=1522 YBD=403 YHG=364>seventy-five " XBD=1911 XHG=1802 YBD=403 YHG=373>years " XBD=2025 XHG=1940 YBD=395 YHG=374>now " XBD=2158 XHG=2057 YBD=395 YHG=365>since " XBD=2254 XHG=2187 YBD=394 YHG=364>the " XBD=2533 XHG=2283 YBD=404 YHG=365>practitioner" XBD=1450 XHG=1339 YBD=438 YHG=407>could " XBD=1606 XHG=1472 YBD=437 YHG=416>excuse " XBD=1781 XHG=1631 YBD=437 YHG=407>himself " XBD=1860 XHG=1801 YBD=438 YHG=408>for " XBD=1956 XHG=1889 YBD=438 YHG=410>not " XBD=2139 XHG=1978 YBD=447 YHG=408>keeping " XBD=2210 XHG=2159 YBD=447 YHG=417>up " XBD=2278 XHG=2237 YBD=438 YHG=409>to " XBD=2391 XHG=2301 YBD=439 YHG=408>date " XBD=2451 XHG=2413 YBD=439 YHG=409>in " XBD=2563 XHG=2472 YBD=439 YHG=406>his" XBD=1544 XHG=1336 YBD=481 YHG=452>treatment " XBD=1613 XHG=1564 YBD=481 YHG=460>on " XBD=1697 XHG=1632 YBD=481 YHG=451>the " XBD=1862 XHG=1716 YBD=490 YHG=452>ground " XBD=1967 XHG=1882 YBD=482 YHG=451>that " XBD=2033 XHG=1987 YBD=482 YHG=452>he " XBD=2130 XHG=2052 YBD=482 YHG=451>had " XBD=2196 XHG=2149 YBD=482 YHG=461>no " XBD=2311 XHG=2217 YBD=482 YHG=452>time " XBD=2373 XHG=2331 YBD=482 YHG=461>or " XBD=2530 XHG=2394 YBD=491 YHG=461>oppor-" XBD=1466 XHG=1336 YBD=533 YHG=495>tunity " XBD=1523 XHG=1483 YBD=524 YHG=496>to " XBD=1658 XHG=1541 YBD=526 YHG=504>assess " XBD=1740 XHG=1674 YBD=525 YHG=495>the " XBD=1866 XHG=1756 YBD=526 YHG=495>value " XBD=1921 XHG=1884 YBD=525 YHG=496>of " XBD=2002 XHG=1937 YBD=526 YHG=496>the " XBD=2100 XHG=2018 YBD=527 YHG=505>new " XBD=2316 XHG=2115 YBD=535 YHG=495>published " XBD=2437 XHG=2332 YBD=536 YHG=496>work " XBD=2531 XHG=2453 YBD=527 YHG=496>and" XBD=1511 XHG=1337 YBD=568 YHG=539>nowhere " XBD=1574 XHG=1535 YBD=568 YHG=540>to " XBD=1689 XHG=1601 YBD=569 YHG=540>turn " XBD=1754 XHG=1714 YBD=569 YHG=540>to " XBD=1837 XHG=1779 YBD=569 YHG=539>for " XBD=1883 XHG=1862 YBD=569 YHG=549>a " XBD=2137 XHG=1908 YBD=581 YHG=539>readymade " XBD=2404 XHG=2162 YBD=570 YHG=532>assessment. " XBD=2532 XHG=2457 YBD=570 YHG=540>For" XBD=1429 XHG=1336 YBD=611 YHG=581>with " XBD=1512 XHG=1462 YBD=611 YHG=582>its " XBD=1645 XHG=1546 YBD=612 YHG=582>June " XBD=1836 XHG=1677 YBD=613 YHG=582>number " XBD=1933 XHG=1868 YBD=613 YHG=583>the " XBD=2207 XHG=1966 YBD=614 YHG=583>Practitioner " XBD=2447 XHG=2239 YBD=622 YHG=584>completes " XBD=2531 XHG=2480 YBD=614 YHG=584>its" XBD=1601 XHG=1338 YBD=664 YHG=625>seventy-fifth " XBD=1730 XHG=1628 YBD=665 YHG=635>year, " XBD=1833 XHG=1758 YBD=656 YHG=626>and " XBD=1909 XHG=1860 YBD=656 YHG=626>its " XBD=2038 XHG=1936 YBD=657 YHG=627>main " XBD=2131 XHG=2065 YBD=666 YHG=627>job " XBD=2197 XHG=2158 YBD=656 YHG=627>in " XBD=2312 XHG=2224 YBD=657 YHG=627>that " XBD=2428 XHG=2338 YBD=666 YHG=627>long " XBD=2532 XHG=2454 YBD=657 YHG=627>and" XBD=1463 XHG=1339 YBD=699 YHG=669>active " XBD=1544 XHG=1480 YBD=699 YHG=669>life " XBD=1625 XHG=1555 YBD=700 YHG=669>has " XBD=1733 XHG=1638 YBD=700 YHG=670>been " XBD=1789 XHG=1750 YBD=699 YHG=671>to " XBD=1897 XHG=1805 YBD=708 YHG=670>keep " XBD=1980 XHG=1915 YBD=700 YHG=670>the " XBD=2129 XHG=1997 YBD=701 YHG=671>doctor " XBD=2184 XHG=2145 YBD=700 YHG=670>in " XBD=2347 XHG=2195 YBD=710 YHG=670>general " XBD=2530 XHG=2362 YBD=709 YHG=671>practice" XBD=1489 XHG=1338 YBD=743 YHG=712>abreast " XBD=1608 XHG=1516 YBD=743 YHG=713>with " XBD=1864 XHG=1636 YBD=744 YHG=713>established " XBD=2146 XHG=1892 YBD=753 YHG=714>therapeutics " XBD=2215 XHG=2173 YBD=745 YHG=723>as " XBD=2403 XHG=2244 YBD=744 YHG=714>distinct " XBD=2531 XHG=2431 YBD=745 YHG=714>from" XBD=1388 XHG=1338 YBD=786 YHG=756>its " XBD=1547 XHG=1414 YBD=787 YHG=756>tender " XBD=1739 XHG=1572 YBD=796 YHG=757>growing " XBD=1905 XHG=1763 YBD=787 YHG=757>shoots. " XBD=2003 XHG=1959 YBD=787 YHG=758>In " XBD=2085 XHG=2028 YBD=788 YHG=757>his " XBD=2262 XHG=2111 YBD=796 YHG=758>preface " XBD=2328 XHG=2288 YBD=787 YHG=759>to " XBD=2422 XHG=2355 YBD=787 YHG=758>the " XBD=2530 XHG=2448 YBD=788 YHG=758>first" XBD=1501 XHG=1339 YBD=830 YHG=800>number " XBD=1588 XHG=1530 YBD=830 YHG=800>for " XBD=1718 XHG=1615 YBD=839 YHG=800>July, " XBD=1857 XHG=1755 YBD=836 YHG=802>1868, " XBD=1945 XHG=1881 YBD=831 YHG=801>the " XBD=2244 XHG=1971 YBD=833 YHG=801>Practitioner’s " XBD=2429 XHG=2266 YBD=831 YHG=801>founder " XBD=2532 XHG=2456 YBD=831 YHG=801>and" XBD=1421 XHG=1339 YBD=874 YHG=844>first " XBD=1586 XHG=1452 YBD=879 YHG=843>editor, " XBD=1660 XHG=1618 YBD=874 YHG=844>F. " XBD=1736 XHG=1692 YBD=874 YHG=844>E. " XBD=1911 XHG=1767 YBD=880 YHG=844>Anstie, " XBD=2136 XHG=1943 YBD=875 YHG=844>described " XBD=2224 XHG=2165 YBD=875 YHG=844>his " XBD=2406 XHG=2254 YBD=883 YHG=844>journal " XBD=2477 XHG=2436 YBD=875 YHG=854>as " XBD=2530 XHG=2508 YBD=875 YHG=855>a" XBD=1481 XHG=1340 YBD=926 YHG=888>special " XBD=1664 XHG=1498 YBD=918 YHG=888>medium " XBD=1741 XHG=1681 YBD=918 YHG=888>for " XBD=1823 XHG=1758 YBD=918 YHG=888>the " XBD=2267 XHG=1845 YBD=919 YHG=888>intercommunication " XBD=2328 XHG=2289 YBD=918 YHG=888>of " XBD=2530 XHG=2350 YBD=918 YHG=888>informa-" XBD=1421 XHG=1338 YBD=961 YHG=931>tion " XBD=1555 XHG=1436 YBD=962 YHG=931>about |>" XBD=1635 XHG=1568 YBD=965 YHG=931>the " XBD=1733 XHG=1648 YBD=962 YHG=940>uses " XBD=1786 XHG=1748 YBD=962 YHG=932>of " XBD=1992 XHG=1799 YBD=967 YHG=931>remedies, " XBD=2083 XHG=2008 YBD=962 YHG=932>and " XBD=2144 XHG=2096 YBD=962 YHG=932>he " XBD=2235 XHG=2159 YBD=962 YHG=932>and " XBD=2306 XHG=2248 YBD=962 YHG=932>his " XBD=2531 XHG=2321 YBD=966 YHG=940>successors" XBD=1537 XHG=1336 YBD=1005 YHG=974>-Lauder " XBD=1742 XHG=1555 YBD=1010 YHG=975>Brunton, " XBD=1912 XHG=1761 YBD=1006 YHG=975>Donald " XBD=2168 XHG=1931 YBD=1010 YHG=975>MacAlister, " XBD=2367 XHG=2196 YBD=1005 YHG=975>Mitchell " XBD=2529 XHG=2395 YBD=1011 YHG=975>Bruce," XBD=1516 XHG=1339 YBD=1049 YHG=1018>Malcolm " XBD=1688 XHG=1543 YBD=1054 YHG=1018>Morris, " XBD=1949 XHG=1718 YBD=1057 YHG=1019>Bosanquet, " XBD=2197 XHG=1977 YBD=1049 YHG=1018>Arbuthnot " XBD=2353 XHG=2224 YBD=1055 YHG=1019>Lane ; " XBD=2438 XHG=2398 YBD=1048 YHG=1020>to " XBD=2532 XHG=2466 YBD=1049 YHG=1019>the" XBD=1490 XHG=1337 YBD=1101 YHG=1064>present " XBD=1667 XHG=1515 YBD=1097 YHG=1061>editors, " XBD=1751 XHG=1695 YBD=1092 YHG=1061>Sir " XBD=1984 XHG=1783 YBD=1101 YHG=1062>Humphry " XBD=2205 XHG=2011 YBD=1092 YHG=1062>Rolleston " XBD=2317 XHG=2240 YBD=1091 YHG=1061>and " XBD=2408 XHG=2340 YBD=1092 YHG=1062>Dr. " XBD=2533 XHG=2433 YBD=1092 YHG=1061>Alan" XBD=1681 XHG=1337 YBD=1136 YHG=1105>Moncrieff-have " XBD=1794 XHG=1704 YBD=1144 YHG=1105>kept " XBD=1880 XHG=1815 YBD=1136 YHG=1106>the " XBD=2005 XHG=1903 YBD=1135 YHG=1114>same " XBD=2167 XHG=2028 YBD=1144 YHG=1105>object, " XBD=2336 XHG=2187 YBD=1144 YHG=1105>though " XBD=2401 XHG=2362 YBD=1136 YHG=1106>in " XBD=2529 XHG=2421 YBD=1136 YHG=1105>these" XBD=1408 XHG=1339 YBD=1180 YHG=1151>900 " XBD=1602 XHG=1424 YBD=1189 YHG=1150>monthly " XBD=1733 XHG=1616 YBD=1180 YHG=1149>issues " XBD=1814 XHG=1749 YBD=1180 YHG=1150>the " XBD=1930 XHG=1827 YBD=1180 YHG=1149>word " XBD=2127 XHG=1945 YBD=1179 YHG=1149>remedies " XBD=2211 XHG=2142 YBD=1179 YHG=1149>has " XBD=2322 XHG=2226 YBD=1179 YHG=1149>been " XBD=2532 XHG=2339 YBD=1179 YHG=1149>stretched" XBD=1377 XHG=1336 YBD=1224 YHG=1195>to " XBD=1541 XHG=1391 YBD=1224 YHG=1193>include " XBD=1620 XHG=1554 YBD=1224 YHG=1194>the " XBD=1751 XHG=1631 YBD=1223 YHG=1193>whole " XBD=1877 XHG=1764 YBD=1232 YHG=1202>range " XBD=1929 XHG=1892 YBD=1222 YHG=1192>of " XBD=2065 XHG=1941 YBD=1222 YHG=1193>useful " XBD=2239 XHG=2077 YBD=1231 YHG=1193>therapy " XBD=2351 XHG=2251 YBD=1222 YHG=1192>from " XBD=2534 XHG=2366 YBD=1222 YHG=1192>cerebral" XBD=1491 XHG=1336 YBD=1277 YHG=1246>surgery " XBD=1552 XHG=1511 YBD=1268 YHG=1239>to " XBD=1792 XHG=1573 YBD=1276 YHG=1236>chiropody, " XBD=1890 XHG=1815 YBD=1266 YHG=1236>and " XBD=2007 XHG=1909 YBD=1266 YHG=1236>from " XBD=2241 XHG=2027 YBD=1275 YHG=1236>paediatrics " XBD=2302 XHG=2262 YBD=1266 YHG=1237>to " XBD=2533 XHG=2323 YBD=1276 YHG=1236>geriatrics.

BRIDGING GAPS IN NERVES

" XBD=1619 XHG=1387 YBD=1387 YHG=1356>EXTENSIVE " XBD=1770 XHG=1634 YBD=1386 YHG=1355>lesions " XBD=1824 XHG=1785 YBD=1386 YHG=1355>of " XBD=2049 XHG=1836 YBD=1394 YHG=1354>peripheral " XBD=2195 XHG=2063 YBD=1385 YHG=1364>nerves " XBD=2281 XHG=2210 YBD=1385 YHG=1364>can " XBD=2343 XHG=2296 YBD=1386 YHG=1354>be " XBD=2531 XHG=2358 YBD=1394 YHG=1355>repaired" XBD=1390 XHG=1337 YBD=1438 YHG=1399>by " XBD=1632 XHG=1407 YBD=1430 YHG=1399>end-to-end " XBD=1778 XHG=1650 YBD=1430 YHG=1401>suture " XBD=1825 XHG=1796 YBD=1429 YHG=1399>if " XBD=1908 XHG=1841 YBD=1429 YHG=1399>the " XBD=2073 XHG=1925 YBD=1438 YHG=1400>stumps " XBD=2154 XHG=2091 YBD=1428 YHG=1408>are " XBD=2336 XHG=2170 YBD=1438 YHG=1398>brought " XBD=2531 XHG=2355 YBD=1439 YHG=1399>together" XBD=1392 XHG=1339 YBD=1483 YHG=1443>by " XBD=1508 XHG=1410 YBD=1483 YHG=1443>joint " XBD=1677 XHG=1528 YBD=1479 YHG=1442>flexion, " XBD=1953 XHG=1698 YBD=1474 YHG=1443>mobilisation " XBD=2015 XHG=1976 YBD=1473 YHG=1443>of " XBD=2102 XHG=2037 YBD=1473 YHG=1443>the " XBD=2235 XHG=2120 YBD=1473 YHG=1451>nerve " XBD=2347 XHG=2259 YBD=1478 YHG=1442>and, " XBD=2407 XHG=2367 YBD=1473 YHG=1443>in " XBD=2531 XHG=2427 YBD=1474 YHG=1452>some" XBD=1456 XHG=1341 YBD=1523 YHG=1496>cases, " XBD=1585 XHG=1471 YBD=1518 YHG=1496>nerve " XBD=1885 XHG=1603 YBD=1527 YHG=1487>transposition. " XBD=1991 XHG=1912 YBD=1518 YHG=1487>The " XBD=2100 XHG=2009 YBD=1517 YHG=1486>limb " XBD=2146 XHG=2114 YBD=1517 YHG=1486>is " XBD=2412 XHG=2157 YBD=1518 YHG=1486>immobilised " XBD=2531 XHG=2431 YBD=1517 YHG=1486>until" XBD=1407 XHG=1341 YBD=1561 YHG=1531>the " XBD=1577 XHG=1428 YBD=1570 YHG=1532>stumps " XBD=1696 XHG=1597 YBD=1561 YHG=1530>have " XBD=1869 XHG=1717 YBD=1561 YHG=1531>become " XBD=2022 XHG=1890 YBD=1561 YHG=1531>united " XBD=2083 XHG=2043 YBD=1561 YHG=1533>at " XBD=2170 XHG=2105 YBD=1560 YHG=1530>the " XBD=2323 XHG=2192 YBD=1561 YHG=1532>suture " XBD=2430 XHG=2343 YBD=1566 YHG=1530>line, " XBD=2531 XHG=2454 YBD=1560 YHG=1530>and" XBD=1369 XHG=1339 YBD=1605 YHG=1575>is " XBD=1474 XHG=1382 YBD=1605 YHG=1575>then " XBD=1682 XHG=1484 YBD=1614 YHG=1574>gradually " XBD=1845 XHG=1689 YBD=1605 YHG=1567>allowed " XBD=1897 XHG=1856 YBD=1604 YHG=1575>to " XBD=2038 XHG=1909 YBD=1605 YHG=1576>return " XBD=2090 XHG=2050 YBD=1604 YHG=1576>to " XBD=2152 XHG=2103 YBD=1604 YHG=1574>its " XBD=2307 XHG=2159 YBD=1604 YHG=1574>normal " XBD=2529 XHG=2319 YBD=1604 YHG=1574>extension." XBD=1416 XHG=1338 YBD=1649 YHG=1618>But " XBD=1544 XHG=1440 YBD=1649 YHG=1628>cases " XBD=1743 XHG=1566 YBD=1657 YHG=1618>reported " XBD=1817 XHG=1765 YBD=1657 YHG=1617>by " XBD=1983 XHG=1842 YBD=1658 YHG=1617>Highet " XBD=2081 XHG=2006 YBD=1648 YHG=1618>and Holmes " XBD=2418 XHG=2276 YBD=1647 YHG=1617>show " XBD=2529 XHG=2440 YBD=1648 YHG=1617>that" XBD=1444 XHG=1336 YBD=1693 YHG=1662>there " XBD=1490 XHG=1458 YBD=1693 YHG=1662>is " XBD=1529 XHG=1507 YBD=1693 YHG=1672>a " XBD=1642 XHG=1544 YBD=1692 YHG=1662>limit " XBD=1698 XHG=1658 YBD=1693 YHG=1664>to " XBD=1780 XHG=1715 YBD=1693 YHG=1662>the " XBD=1869 XHG=1796 YBD=1693 YHG=1662>size " XBD=1924 XHG=1885 YBD=1692 YHG=1661>of " XBD=2005 XHG=1939 YBD=1692 YHG=1661>the " XBD=2093 XHG=2019 YBD=1701 YHG=1671>gap " XBD=2232 XHG=2108 YBD=1692 YHG=1661>which " XBD=2320 XHG=2249 YBD=1692 YHG=1671>can " XBD=2383 XHG=2336 YBD=1691 YHG=1661>be " XBD=2526 XHG=2400 YBD=1692 YHG=1661>closed" XBD=1389 XHG=1336 YBD=1745 YHG=1706>by " XBD=1507 XHG=1414 YBD=1736 YHG=1706>such " XBD=1718 XHG=1532 YBD=1736 YHG=1706>methods. " XBD=1816 XHG=1770 YBD=1736 YHG=1706>In " XBD=1925 XHG=1840 YBD=1736 YHG=1706>four " XBD=2052 XHG=1949 YBD=1736 YHG=1714>cases " XBD=2116 XHG=2077 YBD=1735 YHG=1705>of " XBD=2306 XHG=2140 YBD=1736 YHG=1705>traction " XBD=2460 XHG=2331 YBD=1744 YHG=1705>injury " XBD=2528 XHG=2487 YBD=1736 YHG=1707>to" XBD=1402 XHG=1336 YBD=1780 YHG=1750>the " XBD=1557 XHG=1422 YBD=1780 YHG=1749>lateral " XBD=1759 XHG=1575 YBD=1788 YHG=1749>popliteal " XBD=1893 XHG=1778 YBD=1780 YHG=1758>nerve " XBD=2018 XHG=1915 YBD=1779 YHG=1758>more " XBD=2135 XHG=2040 YBD=1780 YHG=1749>than " XBD=2201 XHG=2161 YBD=1779 YHG=1751>11 " XBD=2297 XHG=2226 YBD=1780 YHG=1758>cm. " XBD=2398 XHG=2320 YBD=1780 YHG=1748>had " XBD=2459 XHG=2419 YBD=1779 YHG=1751>to " XBD=2529 XHG=2482 YBD=1780 YHG=1749>be" XBD=1504 XHG=1336 YBD=1823 YHG=1793>resected " XBD=1666 XHG=1538 YBD=1823 YHG=1793>before " XBD=1840 XHG=1699 YBD=1829 YHG=1795>suture, " XBD=1953 XHG=1876 YBD=1823 YHG=1793>and " XBD=2034 XHG=1985 YBD=1823 YHG=1802>no " XBD=2253 XHG=2072 YBD=1832 YHG=1802>recovery " XBD=2386 XHG=2293 YBD=1823 YHG=1793>took " XBD=2530 XHG=2422 YBD=1831 YHG=1793>place" XBD=1521 XHG=1336 YBD=1876 YHG=1836>although " XBD=1730 XHG=1546 YBD=1867 YHG=1836>the’ limb " XBD=1832 XHG=1745 YBD=1872 YHG=1845>was " XBD=2110 XHG=1858 YBD=1866 YHG=1835>immobilised " XBD=2195 XHG=2136 YBD=1866 YHG=1836>for " XBD=2265 XHG=2225 YBD=1867 YHG=1838>at " XBD=2392 XHG=2296 YBD=1867 YHG=1836>least " XBD=2529 XHG=2422 YBD=1867 YHG=1835>three" XBD=1458 XHG=1335 YBD=1911 YHG=1879>weeks " XBD=1593 XHG=1494 YBD=1910 YHG=1880>after " XBD=1759 XHG=1629 YBD=1912 YHG=1881>suture " XBD=1872 XHG=1794 YBD=1910 YHG=1880>and " XBD=2102 XHG=1913 YBD=1910 YHG=1880>extended " XBD=2336 XHG=2137 YBD=1920 YHG=1880>gradually " XBD=2463 XHG=2373 YBD=1911 YHG=1889>over " XBD=2527 XHG=2505 YBD=1910 YHG=1889>a" XBD=1466 XHG=1335 YBD=1963 YHG=1924>period " XBD=1532 XHG=1492 YBD=1954 YHG=1924>of " XBD=1700 XHG=1557 YBD=1954 YHG=1924>several " XBD=1892 XHG=1726 YBD=1955 YHG=1923>months. " XBD=1989 XHG=1943 YBD=1954 YHG=1924>In " XBD=2037 XHG=2014 YBD=1954 YHG=1933>a " XBD=2204 XHG=2063 YBD=1954 YHG=1923>similar " XBD=2314 XHG=2230 YBD=1955 YHG=1933>case " XBD=2380 XHG=2340 YBD=1954 YHG=1925>in " XBD=2528 XHG=2405 YBD=1954 YHG=1924>which" XBD=1520 XHG=1335 YBD=1998 YHG=1968>resection " XBD=1583 XHG=1544 YBD=1997 YHG=1968>of " XBD=1695 XHG=1606 YBD=2007 YHG=1967>only " XBD=1740 XHG=1720 YBD=1997 YHG=1969>6 " XBD=1835 XHG=1764 YBD=1998 YHG=1977>cm. " XBD=1936 XHG=1858 YBD=1998 YHG=1977>was " XBD=2156 XHG=1958 YBD=2007 YHG=1976>necessary " XBD=2201 XHG=2179 YBD=1997 YHG=1977>a " XBD=2324 XHG=2224 YBD=2007 YHG=1968>good " XBD=2527 XHG=2346 YBD=2006 YHG=1977>recovery" XBD=1368 XHG=1338 YBD=2040 YHG=2011>is " XBD=1426 XHG=1387 YBD=2040 YHG=2011>in " XBD=1628 XHG=1443 YBD=2050 YHG=2004>progress. " XBD=1822 XHG=1681 YBD=2050 YHG=2010>Highet " XBD=1918 XHG=1842 YBD=2041 YHG=2011>and " XBD=2092 XHG=1938 YBD=2041 YHG=2011>Holmes " XBD=2221 XHG=2111 YBD=2050 YHG=2010>point " XBD=2308 XHG=2241 YBD=2041 YHG=2013>out " XBD=2416 XHG=2328 YBD=2041 YHG=2011>that " XBD=2530 XHG=2436 YBD=2050 YHG=2020>very" XBD=1530 XHG=1335 YBD=2085 YHG=2054>extensive " XBD=1765 XHG=1563 YBD=2085 YHG=2054>resections " XBD=1839 XHG=1800 YBD=2085 YHG=2054>of " XBD=2082 XHG=1869 YBD=2094 YHG=2054>peripheral " XBD=2229 XHG=2115 YBD=2085 YHG=2063>nerve " XBD=2399 XHG=2262 YBD=2086 YHG=2054>lesions " XBD=2529 XHG=2432 YBD=2086 YHG=2064>were" XBD=1530 XHG=1335 YBD=2129 YHG=2098>described " XBD=1582 XHG=1543 YBD=2128 YHG=2098>in " XBD=1661 XHG=1596 YBD=2128 YHG=2098>the " XBD=1823 XHG=1674 YBD=2129 YHG=2098>records " XBD=1877 XHG=1837 YBD=2129 YHG=2098>of " XBD=1954 XHG=1889 YBD=2129 YHG=2098>the " XBD=2041 XHG=1967 YBD=2129 YHG=2098>last " XBD=2143 XHG=2053 YBD=2135 YHG=2108>war, " XBD=2229 XHG=2157 YBD=2129 YHG=2098>but " XBD=2330 XHG=2242 YBD=2129 YHG=2098>that " XBD=2410 XHG=2344 YBD=2130 YHG=2099>the " XBD=2528 XHG=2424 YBD=2130 YHG=2108>cases" XBD=1429 XHG=1333 YBD=2172 YHG=2151>were " XBD=1513 XHG=1445 YBD=2172 YHG=2143>not " XBD=1697 XHG=1524 YBD=2173 YHG=2141>followed " XBD=1763 XHG=1712 YBD=2181 YHG=2152>up " XBD=1818 XHG=1779 YBD=2172 YHG=2142>in " XBD=1921 XHG=1829 YBD=2173 YHG=2142>such " XBD=1960 XHG=1936 YBD=2172 YHG=2151>a " XBD=2058 XHG=1973 YBD=2182 YHG=2152>way " XBD=2110 XHG=2067 YBD=2173 YHG=2152>as " XBD=2166 XHG=2125 YBD=2173 YHG=2145>to " XBD=2297 XHG=2186 YBD=2173 YHG=2142>make " XBD=2345 XHG=2315 YBD=2173 YHG=2143>it " XBD=2527 XHG=2363 YBD=2182 YHG=2143>possible" XBD=1376 XHG=1334 YBD=2215 YHG=2187>to " XBD=1525 XHG=1404 YBD=2216 YHG=2194>assess " XBD=1618 XHG=1552 YBD=2216 YHG=2185>the " XBD=1756 XHG=1646 YBD=2216 YHG=2185>effect " XBD=1825 XHG=1785 YBD=2216 YHG=2186>of " XBD=1917 XHG=1851 YBD=2216 YHG=2186>the " XBD=2076 XHG=1945 YBD=2216 YHG=2187>extent " XBD=2145 XHG=2105 YBD=2216 YHG=2186>of " XBD=2238 XHG=2172 YBD=2216 YHG=2186>the " XBD=2451 XHG=2265 YBD=2217 YHG=2187>resection " XBD=2529 XHG=2480 YBD=2216 YHG=2196>on" XBD=1525 XHG=1333 YBD=2268 YHG=2238>recovery. " XBD=1682 XHG=1576 YBD=2268 YHG=2228>They " XBD=1915 XHG=1715 YBD=2260 YHG=2229>examined " XBD=2015 XHG=1949 YBD=2260 YHG=2229>the " XBD=2207 XHG=2050 YBD=2260 YHG=2229>sutured " XBD=2376 XHG=2242 YBD=2260 YHG=2239>nerves " XBD=2527 XHG=2410 YBD=2260 YHG=2230>histo," XBD=1510 XHG=1324 YBD=2312 YHG=2272>logically " XBD=1639 XHG=1529 YBD=2303 YHG=2272>when " XBD=1755 XHG=1662 YBD=2312 YHG=2273>they " XBD=1851 XHG=1774 YBD=2303 YHG=2273>had " XBD=1985 XHG=1870 YBD=2304 YHG=2273>failed " XBD=2048 XHG=2008 YBD=2304 YHG=2275>to " XBD=2238 XHG=2073 YBD=2309 YHG=2282>recover, " XBD=2338 XHG=2257 YBD=2304 YHG=2273>and " XBD=2482 XHG=2361 YBD=2303 YHG=2273>found " XBD=2528 XHG=2506 YBD=2303 YHG=2282>a" XBD=1497 XHG=1333 YBD=2347 YHG=2316>massive " XBD=1784 XHG=1524 YBD=2354 YHG=2316>proliferation " XBD=1851 XHG=1813 YBD=2346 YHG=2317>of " XBD=2046 XHG=1879 YBD=2356 YHG=2317>collagen " XBD=2196 XHG=2073 YBD=2347 YHG=2317>which " XBD=2263 XHG=2224 YBD=2347 YHG=2317>in " XBD=2397 XHG=2293 YBD=2347 YHG=2326>some " XBD=2529 XHG=2425 YBD=2348 YHG=2326>cases" XBD=1410 XHG=1331 YBD=2390 YHG=2359>had " XBD=1497 XHG=1434 YBD=2390 YHG=2359>led " XBD=1562 XHG=1522 YBD=2390 YHG=2361>to " XBD=1775 XHG=1590 YBD=2399 YHG=2359>complete " XBD=2043 XHG=1802 YBD=2390 YHG=2359>obliteration " XBD=2109 XHG=2070 YBD=2390 YHG=2360>of " XBD=2200 XHG=2134 YBD=2390 YHG=2360>the " XBD=2353 XHG=2226 YBD=2396 YHG=2369>nerve, " XBD=2528 XHG=2381 YBD=2399 YHG=2360>though" XBD=1440 XHG=1332 YBD=2433 YHG=2403>there " XBD=1543 XHG=1464 YBD=2433 YHG=2411>was " XBD=1618 XHG=1569 YBD=2433 YHG=2412>no " XBD=1727 XHG=1645 YBD=2442 YHG=2403>sign " XBD=1792 XHG=1754 YBD=2433 YHG=2403>of " XBD=2023 XHG=1818 YBD=2434 YHG=2403>retraction " XBD=2089 XHG=2050 YBD=2433 YHG=2403>of " XBD=2181 XHG=2115 YBD=2433 YHG=2404>the " XBD=2371 XHG=2208 YBD=2443 YHG=2405>stumps. " XBD=2529 XHG=2420 YBD=2442 YHG=2402>They" XBD=1516 XHG=1334 YBD=2476 YHG=2445>conclude " XBD=1649 XHG=1561 YBD=2476 YHG=2446>that " XBD=1869 XHG=1686 YBD=2486 YHG=2446>although " XBD=2130 XHG=1907 YBD=2477 YHG=2446>end-to-end " XBD=2307 XHG=2167 YBD=2476 YHG=2448>-suture " XBD=2435 XHG=2345 YBD=2486 YHG=2455>may " XBD=2525 XHG=2477 YBD=2476 YHG=2446>be" XBD=1497 XHG=1332 YBD=2529 YHG=2488>possible " XBD=1577 XHG=1524 YBD=2529 YHG=2489>by " XBD=1847 XHG=1604 YBD=2530 YHG=2490>appropriate " XBD=2088 XHG=1874 YBD=2529 YHG=2490>technique, " XBD=2166 XHG=2117 YBD=2520 YHG=2499>no " XBD=2319 XHG=2194 YBD=2520 YHG=2489>useful " XBD=2527 XHG=2345 YBD=2529 YHG=2498>recovery" XBD=1405 XHG=1334 YBD=2564 YHG=2543>can " XBD=1467 XHG=1419 YBD=2564 YHG=2532>be " XBD=1667 XHG=1483 YBD=2573 YHG=2533>expected " XBD=1711 XHG=1682 YBD=2563 YHG=2533>if " XBD=1792 XHG=1725 YBD=2564 YHG=2533>the " XBD=1936 XHG=1806 YBD=2573 YHG=2533>length " XBD=1992 XHG=1953 YBD=2564 YHG=2533>of " XBD=2121 XHG=2006 YBD=2564 YHG=2543>nerve " XBD=2305 XHG=2136 YBD=2564 YHG=2533>resected " XBD=2351 XHG=2320 YBD=2564 YHG=2533>is " XBD=2408 XHG=2367 YBD=2564 YHG=2543>so " XBD=2526 XHG=2424 YBD=2573 YHG=2534>large" XBD=1375 XHG=1334 YBD=2608 YHG=2586>as " XBD=1431 XHG=1390 YBD=2608 YHG=2578>to " XBD=1670 XHG=1446 YBD=2608 YHG=2577>necessitate " XBD=1790 XHG=1684 YBD=2617 YHG=2578>great " XBD=2087 XHG=1804 YBD=2617 YHG=2577>postoperative " XBD=2323 XHG=2103 YBD=2617 YHG=2577>stretching, " XBD=2418 XHG=2340 YBD=2607 YHG=2577>and " XBD=2525 XHG=2432 YBD=2616 YHG=2577>they" XBD=1489 XHG=1334 YBD=2660 YHG=2620>analyse " XBD=1541 XHG=1518 YBD=2650 YHG=2629>a " XBD=1675 XHG=1569 YBD=2652 YHG=2620>short " XBD=1816 XHG=1705 YBD=2652 YHG=2620>series " XBD=1885 XHG=1845 YBD=2651 YHG=2620>of " XBD=2015 XHG=1913 YBD=2651 YHG=2629>cases " XBD=2143 XHG=2044 YBD=2651 YHG=2620>from " XBD=2238 XHG=2171 YBD=2650 YHG=2620>the " XBD=2420 XHG=2266 YBD=2660 YHG=2622>present " XBD=2527 XHG=2448 YBD=2651 YHG=2630>war" XBD=1456 XHG=1332 YBD=2695 YHG=2664>which " XBD=1576 XHG=1472 YBD=2704 YHG=2664>gives " XBD=1695 XHG=1593 YBD=2694 YHG=2673>some " XBD=1919 XHG=1712 YBD=2694 YHG=2664>indication " XBD=1976 XHG=1936 YBD=2694 YHG=2663>of " XBD=2058 XHG=1992 YBD=2694 YHG=2664>the " XBD=2277 XHG=2074 YBD=2694 YHG=2663>resections " XBD=2526 XHG=2295 YBD=2702 YHG=2664>compatible" XBD=1426 XHG=1332 YBD=2738 YHG=2707>with " XBD=1640 XHG=1448 YBD=2746 YHG=2716>recovery. " XBD=1922 XHG=1692 YBD=2746 YHG=2707>Experience " XBD=1983 XHG=1943 YBD=2737 YHG=2707>in " XBD=2071 XHG=2004 YBD=2737 YHG=2707>the " XBD=2168 XHG=2093 YBD=2737 YHG=2707>last " XBD=2267 XHG=2189 YBD=2738 YHG=2716>war " XBD=2358 XHG=2289 YBD=2738 YHG=2707>left " XBD=2526 XHG=2381 YBD=2738 YHG=2707>British" XBD=1514 XHG=1335 YBD=2790 YHG=2759>surgeons " XBD=1712 XHG=1534 YBD=2789 YHG=2750>sceptical " XBD=1770 XHG=1731 YBD=2780 YHG=2751>of " XBD=1854 XHG=1788 YBD=2781 YHG=2750>the " XBD=2099 XHG=1874 YBD=2781 YHG=2750>alternative " XBD=2317 XHG=2119 YBD=2789 YHG=2751>operation " XBD=2376 XHG=2337 YBD=2781 YHG=2751>of " XBD=2525 XHG=2395 YBD=2781 YHG=2760>nerve-" XBD=1513 XHG=1333 YBD=2833 YHG=2793>grafting, " XBD=1607 XHG=1530 YBD=2823 YHG=2793>and " XBD=1661 XHG=1622 YBD=2823 YHG=2794>in " XBD=1771 XHG=1681 YBD=2824 YHG=2794>1920 " XBD=1880 XHG=1787 YBD=2832 YHG=2794>they " XBD=2183 XHG=1895 YBD=2824 YHG=2793>recommended " XBD=2230 XHG=2199 YBD=2824 YHG=2794>it " XBD=2338 XHG=2248 YBD=2832 YHG=2794>only " XBD=2395 XHG=2354 YBD=2824 YHG=2803>as " XBD=2434 XHG=2412 YBD=2823 YHG=2802>a " XBD=2525 XHG=2450 YBD=2824 YHG=2794>last|>" XBD=1482 XHG=1333 YBD=2867 YHG=2837>resort.2 " XBD=1641 XHG=1534 YBD=2867 YHG=2836>Since " XBD=1774 XHG=1670 YBD=2872 YHG=2837>then; " XBD=1990 XHG=1805 YBD=2872 YHG=2837>however, " XBD=2272 XHG=2021 YBD=2877 YHG=2837>nerve-grafts " XBD=2400 XHG=2300 YBD=2867 YHG=2837>have " XBD=2527 XHG=2431 YBD=2866 YHG=2836>been" XBD=1578 XHG=1335 YBD=2918 YHG=2879>successfully " XBD=1688 XHG=1595 YBD=2910 YHG=2879>used " XBD=1744 XHG=1704 YBD=2909 YHG=2880>in " XBD=1947 XHG=1759 YBD=2919 YHG=2880>repairing " XBD=2029 XHG=1963 YBD=2909 YHG=2880>the " XBD=2159 XHG=2045 YBD=2910 YHG=2880>facial " XBD=2302 XHG=2175 YBD=2915 YHG=2888>nerve, " XBD=2402 XHG=2325 YBD=2909 YHG=2879>and " XBD=2526 XHG=2424 YBD=2909 YHG=2880>their" XBD=1444 XHG=1334 YBD=2953 YHG=2923>other " XBD=1721 XHG=1471 YBD=2962 YHG=2922>applications " XBD=1810 XHG=1748 YBD=2953 YHG=2931>are " XBD=1948 XHG=1837 YBD=2962 YHG=2922>being " XBD=2164 XHG=1974 YBD=2962 YHG=2922>explored. " XBD=2414 XHG=2215 YBD=2953 YHG=2922>Gutmann " XBD=2525 XHG=2448 YBD=2952 YHG=2921>and

Sanders " XBD=1627 XHG=1505 YBD=2996 YHG=2966>3 have " XBD=1840 XHG=1639 YBD=3005 YHG=2966>compared " XBD=1916 XHG=1850 YBD=2995 YHG=2966>the " XBD=2138 XHG=1926 YBD=2996 YHG=2965>functional " XBD=2284 XHG=2148 YBD=2996 YHG=2966>results " XBD=2336 XHG=2296 YBD=2995 YHG=2965>of " XBD=2523 XHG=2347 YBD=2995 YHG=2961>different" XBD=1444 XHG=1332 YBD=3039 YHG=3009>kinds " XBD=1510 XHG=1471 YBD=3039 YHG=3009>of " XBD=1785 XHG=1535 YBD=3048 YHG=3009>nerve-grafts " XBD=1856 XHG=1818 YBD=3039 YHG=3009>in " XBD=1947 XHG=1881 YBD=3038 YHG=3008>the " XBD=2111 XHG=1972 YBD=3039 YHG=3008>rabbit. " XBD=2398 XHG=2172 YBD=3048 YHG=3008>Autografts " XBD=2524 XHG=2427 YBD=3048 YHG=3017>gave" XBD=1538 XHG=1331 YBD=3082 YHG=3052>recoveries " XBD=1684 XHG=1561 YBD=3082 YHG=3051>which " XBD=1797 XHG=1700 YBD=3082 YHG=3061>were " XBD=1961 XHG=1819 YBD=3082 YHG=3052>similar " XBD=2016 XHG=1977 YBD=3082 YHG=3052>in " XBD=2132 XHG=2039 YBD=3081 YHG=3051>time " XBD=2189 XHG=2150 YBD=3086 YHG=3051>of " XBD=2321 XHG=2213 YBD=3082 YHG=3054>onset " XBD=2417 XHG=2340 YBD=3081 YHG=3051>and " XBD=2526 XHG=2434 YBD=3081 YHG=3051>final" XBD=1466 XHG=1333 YBD=3135 YHG=3095>degree " XBD=1550 XHG=1510 YBD=3125 YHG=3096>to " XBD=1704 XHG=1594 YBD=3125 YHG=3095>those " XBD=1786 XHG=1747 YBD=3125 YHG=3095>of " XBD=1970 XHG=1829 YBD=3125 YHG=3096>suture. " XBD=2270 XHG=2024 YBD=3134 YHG=3094>Homografts " XBD=2410 XHG=2312 YBD=3125 YHG=3103>were " XBD=2526 XHG=2454 YBD=3124 YHG=3094>less" XBD=1548 XHG=1333 YBD=3173 YHG=3138>successful, " XBD=1718 XHG=1571 YBD=3177 YHG=3137>though " XBD=1847 XHG=1739 YBD=3169 YHG=3138>when " XBD=1935 XHG=1869 YBD=3168 YHG=3138>the " XBD=2057 XHG=1956 YBD=3177 YHG=3137>graft " XBD=2155 XHG=2077 YBD=3168 YHG=3146>was " XBD=2305 XHG=2177 YBD=3168 YHG=3137>stored " XBD=2386 XHG=2326 YBD=3167 YHG=3137>for " XBD=2459 XHG=2408 YBD=3177 YHG=3147>up " XBD=2523 XHG=2482 YBD=3167 YHG=3139>to" XBD=1438 XHG=1331 YBD=3212 YHG=3182>three " XBD=1577 XHG=1454 YBD=3212 YHG=3181>weeks " XBD=1634 XHG=1595 YBD=3211 YHG=3181>in " XBD=1823 XHG=1653 YBD=3221 YHG=3181>Ringer’s " XBD=1999 XHG=1834 YBD=3211 YHG=3181>solution " XBD=2056 XHG=2016 YBD=3211 YHG=3183>at " XBD=2114 XHG=2075 YBD=3209 YHG=3181>2° " XBD=2170 XHG=2132 YBD=3210 YHG=3180>C. " XBD=2311 XHG=2182 YBD=3211 YHG=3181>before " XBD=2524 XHG=2328 YBD=3216 YHG=3180>insertion," XBD=1397 XHG=1331 YBD=3254 YHG=3224>the " XBD=1574 XHG=1436 YBD=3256 YHG=3224>results " XBD=1751 XHG=1613 YBD=3263 YHG=3224>closely " XBD=2030 XHG=1790 YBD=3263 YHG=3223>approached " XBD=2178 XHG=2069 YBD=3253 YHG=3223>those " XBD=2258 XHG=2218 YBD=3254 YHG=3224>of " XBD=2524 XHG=2297 YBD=3262 YHG=3224>autografts." XBD=1555 XHG=1333 YBD=3297 YHG=3267>Recoveries " XBD=1674 XHG=1577 YBD=3297 YHG=3276>were " XBD=1775 XHG=1697 YBD=3297 YHG=3267>also " XBD=2050 XHG=1800 YBD=3305 YHG=3267>occasionally " XBD=2160 XHG=2073 YBD=3296 YHG=3275>seen " XBD=2282 XHG=2183 YBD=3296 YHG=3267>after " XBD=2371 XHG=2304 YBD=3296 YHG=3266>the " XBD=2461 XHG=2394 YBD=3296 YHG=3275>use " XBD=2525 XHG=2484 YBD=3296 YHG=3266>of" XBD=1596 XHG=1330 YBD=3340 YHG=3309>alcohol-fixed " XBD=1753 XHG=1621 YBD=3348 YHG=3310>grafts, " XBD=1849 XHG=1779 YBD=3341 YHG=3310>but " XBD=1968 XHG=1874 YBD=3347 YHG=3309>they " XBD=2088 XHG=1991 YBD=3339 YHG=3318>were " XBD=2154 XHG=2112 YBD=3339 YHG=3317>as " XBD=2273 XHG=2178 YBD=3347 YHG=3317>poor " XBD=2375 XHG=2299 YBD=3338 YHG=3308>and " XBD=2442 XHG=2402 YBD=3338 YHG=3317>as " XBD=2522 XHG=2468 YBD=3338 YHG=3309>in-

1. Highet, W. B. and Holmes, W. Brit. J. Surg. 1943, 30, 212.2. MRC Report No. 54, London, 1920.3. Gutmann, E. and Sanders, F. K. Brain, 1942, 65, 373.