The State of Evoluonary Biology - faculty.chas.uni.edu
Transcript of The State of Evoluonary Biology - faculty.chas.uni.edu
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TheStateofEvolu.onaryBiology
150yearssinceDarwin’sOriginofSpecies
50yearssincetheModernSynthesis(Neo‐Darwinism)
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FromtheModernEvolu.onarySynthesis
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• Dobzhansky,1990‐1975
• “Nothinginbiologymakessenseexceptinthelightofevolu.on”
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• JulianHuxley=grandsonofThomasHenryHuxley(Darwin’sbulldog)
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ArchitectsoftheModernSynthesis
R.A.Fisher,TheodosiusDobzhansky,J.B.S.Haldane,SewallWright,E.B.Ford,ErnstMayr,BernhardRensch,SergeiChetverikov,GeorgeGaylordSimpson,andG.LedyardStebbins.
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JianzhiZhang
• h[p://www.umich.edu/~zhanglab/people.htm
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Rule#7:Changesinproteinfunc.onandgeneexpressionarebothimportantinphenotypicevolu.on
• GeneexpressionplaysacentralroleinEvo‐Devo(chapter9)
• h[p://www.pbs.org/wgbh/nova/evolu.on/darwin‐never‐knew.html
• 1:44:00‐1:48:00
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Focus
• Evo‐devo(gene.cbasisofcomplexstructures)• Selec.onistvs.neutralistdebate• Whatformsofselec.onareimportant?– Standardnaturalselec.onvs.kinselec.on– Purifyingselec.onvs.posi.veselec.on
• Whatcausesspecia.on?
• Treeoflifevs.weboflife