The relationship between diameter and number of...

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! "#$ %&’ () *+,-. / !"# !"# !"# !"# $# The relationship between diameter and number of follicles and endometrial thickness and pregnancy success after intrauterine insemination (IUI) 01 / !"# $ % & ’ ( )* +, )* -. /001 23 456 7 $ & 8)(9: -; [email protected] Introduction: Induction ovulation and intrauterine insemination is one of the therapeutic approaches for male infertility. Timing of intrauterine insemination based on number and diameter of follicles and endometrial thickness is essential to maximize pregnancy rate and minimize complications such as hyperstimulation syndrome. Therefore this study was done for evaluation of relationship between pregnancy rate and number and diameter of follicles and endometrial thickness after induction ovulation with clomiphene citrate and IUI. Methods and Materials: In this case-control study in 2001among patients referring to Mashhad infertility center, 100 Patient were randomly assigned to case (50 pregnant women) or control (50 non pregnant women) group. The number and diameter of follicles and endometrial thickness were evaluated and compared by transvaginal ultrasound in these 2 groups in the day of injection of Human Chorionic Gonadotropine. Results of study were analyzed by chi – square, T-test, ANCOVA and multiple regressions. Results: This study was revealed that there is significant differences between pregnancy rate and follicles diameter in two groups (P=0.38, X 2 =5.8). Also in two groups there is significant differences between pregnancy rate and follicles number (P=0.01 , R=0.29). There is significant differences between pregnancy rate and endometrial thickness in two groups (P=0.033 , R=0.29). Conclusion: In this study “pregnancy rate was correlated with number and diameter of follicles and endometrial thickness after induction of ovulation with clomiphene citrate and IUI”. Key words: Pregnancy rate, Diameter of follicle, Number of Follicle, Endometrial thickness line, Induction of ovulation, Clomiphene citrate, Intraterine insemination Abstract

Transcript of The relationship between diameter and number of...

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The relationship between diameter and number of follicles and

endometrial thickness and pregnancy success after intrauterine

insemination (IUI)

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Introduction: Induction ovulation and intrauterine insemination is one of the

therapeutic approaches for male infertility. Timing of intrauterine insemination based

on number and diameter of follicles and endometrial thickness is essential to maximize

pregnancy rate and minimize complications such as hyperstimulation syndrome.

Therefore this study was done for evaluation of relationship between pregnancy rate

and number and diameter of follicles and endometrial thickness after induction

ovulation with clomiphene citrate and IUI.

Methods and Materials: In this case-control study in 2001among patients referring to

Mashhad infertility center, 100 Patient were randomly assigned to case (50 pregnant

women) or control (50 non pregnant women) group. The number and diameter of

follicles and endometrial thickness were evaluated and compared by transvaginal

ultrasound in these 2 groups in the day of injection of Human Chorionic

Gonadotropine.

Results of study were analyzed by chi – square, T-test, ANCOVA and multiple

regressions.

Results: This study was revealed that there is significant differences between

pregnancy rate and follicles diameter in two groups (P=0.38, X

2=5.8). Also in two

groups there is significant differences between pregnancy rate and follicles number

(P=0.01 , R=0.29).

There is significant differences between pregnancy rate and endometrial thickness in

two groups (P=0.033 , R=0.29).

Conclusion: In this study “pregnancy rate was correlated with number and diameter of

follicles and endometrial thickness after induction of ovulation with clomiphene citrate

and IUI”.

Key words: Pregnancy rate, Diameter of follicle, Number of Follicle, Endometrial

thickness line, Induction of ovulation, Clomiphene citrate, Intraterine insemination

Abstract

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