The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton...

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The Power of Activity in The Power of Activity in Rehabilitation Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ Richard Stockton College of NJ New Jersey Occupational Therapy New Jersey Occupational Therapy Association Annual Conference Association Annual Conference October 1, 2011 October 1, 2011

Transcript of The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton...

Page 1: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

The Power of Activity in The Power of Activity in RehabilitationRehabilitation

Victoria Schindler, PhD, OTR, BCMH, FAOTAVictoria Schindler, PhD, OTR, BCMH, FAOTARichard Stockton College of NJRichard Stockton College of NJ

New Jersey Occupational Therapy New Jersey Occupational Therapy Association Annual ConferenceAssociation Annual Conference

October 1, 2011October 1, 2011

Page 2: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

Choose an activity to do for Choose an activity to do for 15 minutes. It should be 15 minutes. It should be one that is rewarding, one that is rewarding, relaxing and/or would relaxing and/or would elevate your mood.elevate your mood.• Crossword PuzzleCrossword Puzzle• Read a NewsletterRead a Newsletter• DrawingDrawing• Listen to MusicListen to Music• Go for a WalkGo for a Walk• Talk with a FriendTalk with a Friend• MeditateMeditate• Take a NapTake a Nap• Any other Activity of your ChoiceAny other Activity of your Choice

Page 3: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

Take a HandoutTake a Handout

Use the Handout to Select Use the Handout to Select the words that describe the words that describe the way you are thinking the way you are thinking

and feeling right NOWand feeling right NOW

Page 4: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

Take a HandoutTake a Handout

Select the words that Select the words that describe the way you describe the way you

were thinking and were thinking and feeling during the feeling during the

activityactivity

Page 5: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

HandoutHandout

Compare the two lists and Compare the two lists and note your findingsnote your findings

Page 6: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

Power of Activity in Power of Activity in Rehabilitation - AgendaRehabilitation - Agenda

• Neurological Underpinnings of Neurological Underpinnings of Engagement in Positive ActivityEngagement in Positive Activity

• Psychological Aspects of ActivityPsychological Aspects of Activity

• FLOWFLOW

• Neuroplasticity of the BrainNeuroplasticity of the Brain

• How to Develop Meaningful ActivityHow to Develop Meaningful Activity

• Resistance to Treatment with ActivityResistance to Treatment with Activity

Page 7: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

Neurological Underpinnings of Neurological Underpinnings of Engagement in Positive Engagement in Positive ActivityActivity• Imaging scans (e.g., PET Scans, MRI Imaging scans (e.g., PET Scans, MRI

and EEGs).and EEGs).

• Activities as REWARDINGActivities as REWARDING

• Activities promoting RELAXATIONActivities promoting RELAXATION

• Activities that ELEVATE MOODActivities that ELEVATE MOOD

Page 8: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

The Brain’s Reward CenterThe Brain’s Reward Center• Mesocorticolimbic Mesocorticolimbic

systemsystem– Cortex, Midbrain, Cortex, Midbrain,

Limbic systemLimbic system

• Distinguishes Distinguishes activities that are activities that are pleasurable and pleasurable and should be should be repeated from repeated from those which are those which are harmful and harmful and should be avoidedshould be avoided

Page 9: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

Neurological Basis of Neurological Basis of ActivityActivity• Primary Primary

Neurotransmitters in Neurotransmitters in the Brain’s reward the Brain’s reward systemsystem– DopamineDopamine– GlutamateGlutamate

• The brain’s reward The brain’s reward system is activated system is activated and dopamine and and dopamine and glutamate are glutamate are increased during times increased during times we are engaged in we are engaged in positive activitypositive activity

Page 10: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

Activities activating the brain’s Activities activating the brain’s reward systemreward system• MusicMusic• EatingEating• SexSex• Engaging in positive Engaging in positive

conversationconversation• Fine artsFine arts

– Drawing, Painting, SculptingDrawing, Painting, Sculpting

• SportsSports– Stimulate reticular Stimulate reticular

receptorsreceptors– Stimulate vestibular Stimulate vestibular

receptorsreceptors

• HumorHumor

Page 11: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

– Physiological Physiological ResponsesResponses

• Blood pressure, Blood pressure, heart rate, heart rate, respirationrespiration

– Increased Immune Increased Immune System ResponsesSystem Responses

– Neurological Neurological ResponsesResponses

• Alpha, theta and Alpha, theta and delta wave patternsdelta wave patterns

Page 12: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

Neurological Basis - Neurological Basis - RelaxationRelaxation• Characteristics of Activity that Promote the Characteristics of Activity that Promote the

Relaxation Response – Herbert BensonRelaxation Response – Herbert Benson– Performed in quiet environmentPerformed in quiet environment– Enhances one’s ability to concentrate and Enhances one’s ability to concentrate and

focus inwardly on the task at handfocus inwardly on the task at hand– Enhances one’s ability to disregard everyday Enhances one’s ability to disregard everyday

thoughts and worriesthoughts and worries– Requires focused attention on a repetitive Requires focused attention on a repetitive

mental stimulusmental stimulus

Page 13: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

– Progressive Progressive relaxationrelaxation

– VisualizationVisualization– Guided imageryGuided imagery– CraftsCrafts– YogaYoga– MeditationMeditation– ArtArt– MusicMusic

Page 14: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

•““the awareness that emerges by paying the awareness that emerges by paying attention on purpose, in the present attention on purpose, in the present moment, and non-judgmentally, to the moment, and non-judgmentally, to the unfolding of experience, moment-by-unfolding of experience, moment-by-moment…with an affectionate, moment…with an affectionate, compassionate quality within the attending, compassionate quality within the attending, a sense of openhearted, friendly presence”a sense of openhearted, friendly presence”– http//www.psych.stanford.edu/-pgoldin/http//www.psych.stanford.edu/-pgoldin/

Buddhism/MBSR2003_Kabat-Zinn.pdfBuddhism/MBSR2003_Kabat-Zinn.pdf

Page 15: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

MINDFULNESSMINDFULNESS

• Mindfulness TrainingMindfulness Training– MeditationMeditation– Become aware of one’s thoughtsBecome aware of one’s thoughts

•Negative, judgmental, self-destructive Negative, judgmental, self-destructive thoughtsthoughts

•Catch these thoughtsCatch these thoughts

•Challenge their validityChallenge their validity

•Release themRelease them

Page 16: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

Elevate MoodElevate Mood

•Neural activity in the left Neural activity in the left hemisphere has been linked to hemisphere has been linked to positive mood, feelings of well-positive mood, feelings of well-being and emotional stabilitybeing and emotional stability

•PET Scans and MRIs have shown PET Scans and MRIs have shown that people with depression have that people with depression have a marked decrease of activity and a marked decrease of activity and blood flow in the left hemisphereblood flow in the left hemisphere

Page 17: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

Elevate MoodElevate Mood

• Activities that Activities that promote blood promote blood flow and neural flow and neural activity in the left activity in the left hemisphere have hemisphere have been shown to been shown to alleviate feelings alleviate feelings of depressionof depression

Page 18: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

Neurological Response – Neurological Response – Elevate MoodElevate Mood

• The left hemisphere is responsible for The left hemisphere is responsible for language skills, math skills, language skills, math skills, categorization skills, and sequencing categorization skills, and sequencing skillsskills– Example of activitiesExample of activities

•Word finding puzzles, crossword puzzlesWord finding puzzles, crossword puzzles• Jewelry making, cooking, craftsJewelry making, cooking, crafts

•Cognitive Behavioral Cognitive Behavioral Frame of ReferenceFrame of Reference

Page 19: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

““An optimal experience in An optimal experience in which people feel intense which people feel intense pleasure and satisfaction pleasure and satisfaction while deeply engaged in while deeply engaged in desired activity”desired activity”

--CsikszentmihalyiCsikszentmihalyi

Page 20: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

Csikszentmihalyi, M. (1997)Csikszentmihalyi, M. (1997)

FLOWFLOW

• A term that describes the positive feeling A term that describes the positive feeling we have when we are absorbed in a we have when we are absorbed in a pleasurable activitypleasurable activity

• Totally immersed in the present momentTotally immersed in the present moment

• Lose sense of timeLose sense of time

• Lose sense of fear or anxiety; worries fadeLose sense of fear or anxiety; worries fade

• Participating in the activity is its own Participating in the activity is its own rewardreward

Page 21: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

Csikszentmihalyi, M. (1997)Csikszentmihalyi, M. (1997)

Research on FLOWResearch on FLOW• Experience Sampling Experience Sampling

MethodMethod– Signal participants at Signal participants at

random timesrandom times– Doing, thinking, alone, or Doing, thinking, alone, or

with otherswith others– Rate on various numeric Rate on various numeric

scalesscales• HappinessHappiness

• ConcentrationConcentration

• MotivationMotivation

• Self-esteemSelf-esteem

– Can follow changes in moodCan follow changes in mood

Page 22: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

Experiences with FLOWExperiences with FLOW

• Female Dx’d with Chronic SCZ; Female Dx’d with Chronic SCZ; hospitalized for over 10 yearshospitalized for over 10 years

• Individuals diagnosed with Individuals diagnosed with DepressionDepression

• Quality of LifeQuality of Life

• Increasing FlowIncreasing Flow

Page 23: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

Csikszentmihalyi, M. (1997)Csikszentmihalyi, M. (1997)

Activities that promote Activities that promote FLOWFLOW• Sports and exerciseSports and exercise

• Crafts - Knitting and Crafts - Knitting and needlepointneedlepoint

• GardeningGardening

• Hiking Hiking

• CookingCooking

• Play a musical instrumentPlay a musical instrument

• SocializingSocializing

• Active Leisure as opposed Active Leisure as opposed to Passive Leisureto Passive Leisure

Page 24: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

Developing FlowDeveloping Flow• Develop curiosity and Develop curiosity and

interestinterest– In routine tasksIn routine tasks– In new tasks and In new tasks and

activitiesactivities

• Reevaluate our present Reevaluate our present tasks and routinestasks and routines– Are they really Are they really

necessary?necessary?– Control time carefullyControl time carefully

• Control psychic energyControl psychic energy– Control concentrationControl concentration– Control our thoughtsControl our thoughts

Page 25: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

NeuroplasticityNeuroplasticity

• The brain’s ability to change – for better The brain’s ability to change – for better or worse – throughout the life spanor worse – throughout the life span

• Process involves forming neuronal Process involves forming neuronal connections in response to information connections in response to information derived from experiences in the derived from experiences in the environment, sensory stimulation, and environment, sensory stimulation, and normal development.normal development.

Dodge, 2007; McCormack, 2009; Merzenich, 2001; Nudo, 2008Dodge, 2007; McCormack, 2009; Merzenich, 2001; Nudo, 2008

Page 26: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

NeuroplasticityNeuroplasticity

• The brain’s ability to grow and The brain’s ability to grow and change into old age as long as it is change into old age as long as it is engaged in meaningful occupations.engaged in meaningful occupations.

Christiansen and Baum, 2005; McCormack, 2009.Christiansen and Baum, 2005; McCormack, 2009.

Page 27: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

What are the characteristics of What are the characteristics of activity that make it activity that make it meaningful?meaningful?• NeurologicalNeurological

– Promote RewardPromote Reward– Promote RelaxationPromote Relaxation– Elevate MoodElevate Mood

• PsychologicalPsychological– FLOWFLOW

Page 28: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

How to Develop Meaningful How to Develop Meaningful ActivityActivity

• Requires both physical and mental involvementRequires both physical and mental involvement

• Defined according to each individual; cannot be Defined according to each individual; cannot be defined by one individual for another individualdefined by one individual for another individual

• Elicits choiceElicits choice

• Facilitates developmentFacilitates development

• Must have meaning for the clientMust have meaning for the client

• Must be related to the client’s goalsMust be related to the client’s goals

• Must be of interest to the clientMust be of interest to the client

Page 29: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

How do we Develop FLOW in How do we Develop FLOW in Activities?Activities?

• Include the client in the Include the client in the selection of activitiesselection of activities

• Help them to identify Help them to identify activities they enjoyactivities they enjoy

• Teach our clients to Teach our clients to become absorbed in become absorbed in activityactivity

• Teach our clients to Teach our clients to control their control their concentration thereby concentration thereby decreasing distracting decreasing distracting thoughtsthoughts

• Use the flow experience Use the flow experience to manage anxiety, anger, to manage anxiety, anger, and depressionand depression

Page 30: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

Resistance to Engagement in Resistance to Engagement in Activity Activity

• Create an environment in which choices Create an environment in which choices can be madecan be made

• Choices range from small to large Choices range from small to large concernsconcerns

• Client will reject invitations to chooseClient will reject invitations to choose• Staff must not despair and stop caringStaff must not despair and stop caring• Staff should model hope and continue to Staff should model hope and continue to

offer optionsoffer options• Provide opportunity to fail and to try againProvide opportunity to fail and to try again

Page 31: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

Select the words that Select the words that describe the way you were describe the way you were thinking and feeling during thinking and feeling during

the activitythe activity• What about the activity led to your What about the activity led to your

thoughts and feelings during the thoughts and feelings during the activity?activity?

• What about this is universal?What about this is universal?

• What about this is unique to you?What about this is unique to you?

Page 32: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

Select the words that Select the words that describe the way you are describe the way you are thinking and feeling right thinking and feeling right

NOWNOW• What were the components of the What were the components of the

activity that produced this “after” activity that produced this “after” effecteffect

• How does this relate to the How does this relate to the psychological and neurological psychological and neurological effects of activity on the brain?effects of activity on the brain?

Page 33: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

SUMMARYSUMMARY

•How can you use this How can you use this information to influence information to influence the way you create and/or the way you create and/or choose activities in your choose activities in your practice?practice?

Page 34: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

Thank You very much Thank You very much for your attentionfor your attention!!

Page 35: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

References – Psychological References – Psychological Aspects of ActivityAspects of Activity• Breines, E. (1984). An attempt to define purposeful activity. Breines, E. (1984). An attempt to define purposeful activity. The American Journal of The American Journal of • Occupational Therapy, 38(8), Occupational Therapy, 38(8), 543-544. 543-544. • Csikszentmihalyi, M (1997). Finding Flow: The Psychology of Engagement with Everyday Life. Basic Books Csikszentmihalyi, M (1997). Finding Flow: The Psychology of Engagement with Everyday Life. Basic Books • English, C., Kasch, M., Silverman, P., & Walker, S. (1982). On the role of the occupational English, C., Kasch, M., Silverman, P., & Walker, S. (1982). On the role of the occupational • therapist in physical disabilities. therapist in physical disabilities. The American Journal of Occupational Therapy, 36(3),The American Journal of Occupational Therapy, 36(3),• 199-202.199-202.• Heck, S.A. (1988). The effect of purposeful activity on pain tolerance. Heck, S.A. (1988). The effect of purposeful activity on pain tolerance. The American Journal of The American Journal of • Occupational Therapy, 42(9), Occupational Therapy, 42(9), 577-581.577-581.• Hong, C.S., & Yates, P. (1995). Purposeful activities? What are they? Hong, C.S., & Yates, P. (1995). Purposeful activities? What are they? The British Journal of The British Journal of • Occupational Therapy, 58(2), Occupational Therapy, 58(2), 75-76. 75-76. • Kasch, M.C., & Kircher, M.A. (1985). Letters to the editor: Motivation and activity. Kasch, M.C., & Kircher, M.A. (1985). Letters to the editor: Motivation and activity. The The • American Journal of Occupational Therapy, 39(2), American Journal of Occupational Therapy, 39(2), 114-116. 114-116. • Kircher, M.A., (1984). Motivation as a factor of perceived exertion in purposeful versus Kircher, M.A., (1984). Motivation as a factor of perceived exertion in purposeful versus • nonpurposeful activity. nonpurposeful activity. The American Journal of Occupational Therapy, 38(3), The American Journal of Occupational Therapy, 38(3), 165-170. 165-170. • Maurer, T.L., Smith, D.A., & Armetta, C.L. (1989). Maurer, T.L., Smith, D.A., & Armetta, C.L. (1989). Single purpose vs. added purpose activity: Single purpose vs. added purpose activity: • Performance comparisons with chronic schizophrenics. Performance comparisons with chronic schizophrenics. Occupational Therapy in Mental Occupational Therapy in Mental • Health, 9(3), Health, 9(3), 9-20. 9-20. • Perrins-Margalis, N.M., Rugletic, J, Schepis, N.M., Stepanski, H.R., & Walsh, M.A. (2000). The Perrins-Margalis, N.M., Rugletic, J, Schepis, N.M., Stepanski, H.R., & Walsh, M.A. (2000). The • immediate effects of a group-based horticulture experience on the quality of life of immediate effects of a group-based horticulture experience on the quality of life of • persons with chronic mental illness. persons with chronic mental illness. Occupational Therapy in Mental Health, 16(1), Occupational Therapy in Mental Health, 16(1), • 15-31.15-31.• Rebeiro, K.L., & Polgar, J.M. (1999). Enabling occupational performance: Optimal experiences Rebeiro, K.L., & Polgar, J.M. (1999). Enabling occupational performance: Optimal experiences • in therapy. in therapy. Canadian Journal of Occupational Therapy, 66(1), Canadian Journal of Occupational Therapy, 66(1), 14-21.14-21.• Steinbeck, T. M. (1986). Purposeful activity and performance. Steinbeck, T. M. (1986). Purposeful activity and performance. The American Journal of The American Journal of • Occupational Therapy, 40(8), Occupational Therapy, 40(8), 529-534. 529-534. • Thibodeaux, C.S., & Ludwig, F.M. (1988). Intrinsic motivation in product-oriented and Thibodeaux, C.S., & Ludwig, F.M. (1988). Intrinsic motivation in product-oriented and • non-product oriented activities. non-product oriented activities. The American Journal of Occupational Therapy, 42(3), The American Journal of Occupational Therapy, 42(3), • 169-175. 169-175. • Yoder, R.M., Nelson, D.L., & Smith, D.A. (1989). Added-purpose versus rote exercise in femaleYoder, R.M., Nelson, D.L., & Smith, D.A. (1989). Added-purpose versus rote exercise in female• nursing home residents. nursing home residents. The American Journal of Occupational Therapy, 43(9),The American Journal of Occupational Therapy, 43(9), 581-586. 581-586.

Page 36: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

References – Neurological References – Neurological Aspects of ActivityAspects of Activity• Antoni, M. H. (2000). Cognitive-based stress management intervention effects on anxiety, 24-hour Antoni, M. H. (2000). Cognitive-based stress management intervention effects on anxiety, 24-hour

urinary norepinephrine output, and T-cytotoxic/suppressor cells over time among symptomatic HIV urinary norepinephrine output, and T-cytotoxic/suppressor cells over time among symptomatic HIV infected gay men. infected gay men. Journal of Consulting Clinical PsychologistJournal of Consulting Clinical Psychologist,, 68 68, 31-45., 31-45.

• Aftanas, L., & Golosheykin, S. (2005). Impact of regular meditation practice on EEG activity at rest Aftanas, L., & Golosheykin, S. (2005). Impact of regular meditation practice on EEG activity at rest and during evoked negative emotions. and during evoked negative emotions. International Journal of Neuroscience, 115International Journal of Neuroscience, 115, 893-909., 893-909.

• Astin, J. A. (1997). Stress reduction through mindfulness meditation. Effects on psychological Astin, J. A. (1997). Stress reduction through mindfulness meditation. Effects on psychological symptomatology, sense of control, and spiritual experiences. symptomatology, sense of control, and spiritual experiences. Psychotherapthy and Psychosomatics, Psychotherapthy and Psychosomatics, 6666(2), 97-106.(2), 97-106.

• Bedard, M., Felteau, M., Mazmanian, D., Fedyk, K., Klein, R., Richardson, J., et al. (2003). Pilot Bedard, M., Felteau, M., Mazmanian, D., Fedyk, K., Klein, R., Richardson, J., et al. (2003). Pilot evaluation of a mindfulness-based intervention to improve quality of life among individuals who evaluation of a mindfulness-based intervention to improve quality of life among individuals who sustained traumatic brain injuries. sustained traumatic brain injuries. Disability Rehabilitation, 25Disability Rehabilitation, 25, 722-731., 722-731.

• Benson, H., Beary, J. F., & Carol, M. P. (1974). The relaxation response. Benson, H., Beary, J. F., & Carol, M. P. (1974). The relaxation response. Psychiatry, 37Psychiatry, 37, 37-46., 37-46.• Benson, H., & Corliss, J. (2004, September 27). Ways to calm your mind. Benson, H., & Corliss, J. (2004, September 27). Ways to calm your mind. NewsweekNewsweek, 47., 47.• Bhattacharya, J., & Petsche, H. (2005). Drawing on mind’s canvas: Differences in cortical integration Bhattacharya, J., & Petsche, H. (2005). Drawing on mind’s canvas: Differences in cortical integration

patterns between artists and non-artists. patterns between artists and non-artists. Human Brain Mapping, 26Human Brain Mapping, 26, -14., -14.• Blood, A. J., & Zatorre, R. J. (2001). Intensely pleasurable responses to music correlate with activity Blood, A. J., & Zatorre, R. J. (2001). Intensely pleasurable responses to music correlate with activity

in brain regions implicated in reward and emotion. in brain regions implicated in reward and emotion. PNAS, 98PNAS, 98, 11818-11823., 11818-11823.• Blood, A. J., Zatorre, R. J., Bermudez, P., & Evans, A. C. (1999). Emotional responses to pleasant and Blood, A. J., Zatorre, R. J., Bermudez, P., & Evans, A. C. (1999). Emotional responses to pleasant and

unpleasant music correlate with activity in paralimbic brain regions [Electronic version]. unpleasant music correlate with activity in paralimbic brain regions [Electronic version]. Nature Nature Neuroscience, 2Neuroscience, 2, 382-387., 382-387.

• Brown, S., Martinez, M. J., Hodges, D. A., Fox, P. T., & Parsons, L. M. (2004). The song system of the Brown, S., Martinez, M. J., Hodges, D. A., Fox, P. T., & Parsons, L. M. (2004). The song system of the human brain [Electronic version]. human brain [Electronic version]. Cognitive Brain Research, 20Cognitive Brain Research, 20, 363-375., 363-375.

• Brown, S., Martinez, M. J., & Parsons, L. M. (2004). Passive music listening spontaneously engages Brown, S., Martinez, M. J., & Parsons, L. M. (2004). Passive music listening spontaneously engages limbic and paralimbic systems. limbic and paralimbic systems. NeuroReport, 15NeuroReport, 15, 2033-2037., 2033-2037.

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References – Neurological References – Neurological Aspects of Activity (continued).Aspects of Activity (continued).• Chau, D. T., Royh, R. M., & Green, A. I. (2004). The neural circuitry of reward and its relevance to psychiatric disorders. Chau, D. T., Royh, R. M., & Green, A. I. (2004). The neural circuitry of reward and its relevance to psychiatric disorders.

Current Psychiatry Reports, 6Current Psychiatry Reports, 6, 391-399., 391-399.• Comstock, G., & Scharrer, E. (1999). Comstock, G., & Scharrer, E. (1999). Television: What’s on, who’s watching and what it meansTelevision: What’s on, who’s watching and what it means. San Diego: Academic . San Diego: Academic

Press.Press.• Davidson, R. J., Jackson, D. C., & Kalin, N. H. (2000). Emotion, plasticity, context, and regulation: Perspectives from Davidson, R. J., Jackson, D. C., & Kalin, N. H. (2000). Emotion, plasticity, context, and regulation: Perspectives from

affective neuroscience. affective neuroscience. Psychology Bulletin, 126Psychology Bulletin, 126, 890-909., 890-909.• Davidson, R. J., Kabat-Zinn, J., Schumacher, J., Rosenkranz, M., Muller, D., Santorelli, S. F., et al. (2003). Alterations in Davidson, R. J., Kabat-Zinn, J., Schumacher, J., Rosenkranz, M., Muller, D., Santorelli, S. F., et al. (2003). Alterations in

brain and Immune Function produced by mindfulness meditation [Electronic version]. brain and Immune Function produced by mindfulness meditation [Electronic version]. Psychosomatic Medicine, 65Psychosomatic Medicine, 65, 564-, 564-570.570.

• Delvenne, V. (1999). Brain glucose metabolism in eating disorders assessed by positron emission tomography Delvenne, V. (1999). Brain glucose metabolism in eating disorders assessed by positron emission tomography [Electronic version]. [Electronic version]. International Journal of Eating Disorders, 25International Journal of Eating Disorders, 25(1), 29-37.(1), 29-37.

• Elliott, R., Friston, K. J., & Dolan, R. J. (2000). Dissociable neural responses in human reward systems. Elliott, R., Friston, K. J., & Dolan, R. J. (2000). Dissociable neural responses in human reward systems. Journal of Journal of Neuroscience, 20Neuroscience, 20, 6159-6165., 6159-6165.

• Farias, D., Davis, C., & Harrington, G. (2005). Drawing: It’s contribution to naming in aphasia [Electronic version]. Farias, D., Davis, C., & Harrington, G. (2005). Drawing: It’s contribution to naming in aphasia [Electronic version]. Brain Brain LanguageLanguage..

• Fornazzari, L. R. (2005). Preserved painting creativity in an artist with Alzheimer’s disease. Fornazzari, L. R. (2005). Preserved painting creativity in an artist with Alzheimer’s disease. European Journal of European Journal of Neurology, 12Neurology, 12, 419-424., 419-424.

• Friedland, R. P., Fritsch, T., Smyth, K. A., Koss, E., Lerner, A. J., Chen, C. H., et al. (2001). Patients with Alzheimer’s Friedland, R. P., Fritsch, T., Smyth, K. A., Koss, E., Lerner, A. J., Chen, C. H., et al. (2001). Patients with Alzheimer’s disease have reduced premorbid activities compared to healthy controls [Electronic version]. disease have reduced premorbid activities compared to healthy controls [Electronic version]. Proceedings of the Proceedings of the National Academy of Sciences, 98National Academy of Sciences, 98, 3440-3445., 3440-3445.

• Gautier, J. (1999). Regions of the human brain affected during a liquid-metal taste perception in the fasting state: A Gautier, J. (1999). Regions of the human brain affected during a liquid-metal taste perception in the fasting state: A positron emission tomography study. positron emission tomography study. American Journal of Clinical Nutrition, 70American Journal of Clinical Nutrition, 70(5), 806-810.(5), 806-810.

• Halpern, A. R., & Zatorre, R. J. (1999). When that tune runs through your head: A PET investigation of auditory imagery Halpern, A. R., & Zatorre, R. J. (1999). When that tune runs through your head: A PET investigation of auditory imagery for familiar melodies. for familiar melodies. Cerebral Cortex, 9Cerebral Cortex, 9, 697-704., 697-704.

• Hommer, D. W. (1999). Functional imaging of craving. Hommer, D. W. (1999). Functional imaging of craving. Alcohol Research and Health, 23Alcohol Research and Health, 23, 187-196., 187-196.• Hutchinson, S., Lee, L. H., Gaab, N., & Schlaug, G. (2003). Cerebellar volume of musicians Hutchinson, S., Lee, L. H., Gaab, N., & Schlaug, G. (2003). Cerebellar volume of musicians

Page 38: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

References – Neurological References – Neurological Aspects of Activity (continued).Aspects of Activity (continued).• Jackson, S. (1996). Toward a conceptual understanding of the flow experience in elite athletes. Jackson, S. (1996). Toward a conceptual understanding of the flow experience in elite athletes. Research Research

Quarterly for Exercise and Sport, 67Quarterly for Exercise and Sport, 67(1), 76-90.(1), 76-90.• Jacobs, G. D. (2001). The physiology of mind-body interactions: The stress response and the relaxation Jacobs, G. D. (2001). The physiology of mind-body interactions: The stress response and the relaxation

response [Electronic version]. response [Electronic version]. Journal of Alternative and Complementary Medicine, 7Journal of Alternative and Complementary Medicine, 7(Suppl. 1), S83-92.(Suppl. 1), S83-92.• Kabat-Zinn, J., Lipworth, L., Burney, R., & Sellers, W. (1986). Four years follow-up of a meditation-based Kabat-Zinn, J., Lipworth, L., Burney, R., & Sellers, W. (1986). Four years follow-up of a meditation-based

program for the self-regulation of chronic pain: Treatment outcomes and compliance. program for the self-regulation of chronic pain: Treatment outcomes and compliance. Clinical Journal of Clinical Journal of Pain, 2Pain, 2, 159-173., 159-173.

• Kabat-Zinn, J., Massion, A. O., Kristeller, J., Peterson, L. G., Fletcher, K. E., Pbert, L., et al. (1992). Kabat-Zinn, J., Massion, A. O., Kristeller, J., Peterson, L. G., Fletcher, K. E., Pbert, L., et al. (1992). Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders. Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders. American Journal of Psychiatry, 149American Journal of Psychiatry, 149, 936-943., 936-943.

• Kalb, C. (2004, September 27). Buddha lessons: A technique called mindfulness teaches how to step back Kalb, C. (2004, September 27). Buddha lessons: A technique called mindfulness teaches how to step back from pain and worries of life. from pain and worries of life. NewsweekNewsweek, 48, 51., 48, 51.

• Koelsch, S., Kasper, E., Sammler, D., Schulze, K., Gunter, T., Friedericki, A. D. (2004). Music, language and Koelsch, S., Kasper, E., Sammler, D., Schulze, K., Gunter, T., Friedericki, A. D. (2004). Music, language and meaning: Brain signatures of semantic processing. meaning: Brain signatures of semantic processing. Nature Neuroscience, 7Nature Neuroscience, 7, 302-307., 302-307.

• Koelsch, S., Fritz, T., Crammon, D. Y., Muller, K., & Friederici, A. D. (2005). Investigating emotion with Koelsch, S., Fritz, T., Crammon, D. Y., Muller, K., & Friederici, A. D. (2005). Investigating emotion with music: An fMRI study [Electronic version]. music: An fMRI study [Electronic version]. Human Brain MappingHuman Brain Mapping, online before publication., online before publication.

• Koepp, M. J., Gunn, R. N., Lawrence, A. D. Cunningham, V. J., Dagher, A., Jones, T., Brooks, D. J., et al. Koepp, M. J., Gunn, R. N., Lawrence, A. D. Cunningham, V. J., Dagher, A., Jones, T., Brooks, D. J., et al. (1998). Evidence for striatal dopamine release during a video game. (1998). Evidence for striatal dopamine release during a video game. Nature, 393Nature, 393, 266-268., 266-268.

• Lindstrom, H. A., Fritsch, T., Petot, G., Smyth, K. A., Chen, C. H., Debanne, S. M., et al. (2005). The Lindstrom, H. A., Fritsch, T., Petot, G., Smyth, K. A., Chen, C. H., Debanne, S. M., et al. (2005). The relationship between television viewing in midlife and the development of Alzheimer’s disease in a case-relationship between television viewing in midlife and the development of Alzheimer’s disease in a case-control study. control study. Brain and Cognition, 58Brain and Cognition, 58, 157-165., 157-165.

• Lo Coco, D., & Nacci, P. (2004). Frontotemporal dementia presenting with pathological gambling. Lo Coco, D., & Nacci, P. (2004). Frontotemporal dementia presenting with pathological gambling. Journal Journal of Neuropsychiatry Clinical Neuroscience, 16of Neuropsychiatry Clinical Neuroscience, 16, 117., 117.

• Maurer, K., & Prvulovic, D. (2004). Paintings of an artist with Alzheimer’s disease: Visuoconstructional Maurer, K., & Prvulovic, D. (2004). Paintings of an artist with Alzheimer’s disease: Visuoconstructional deficits during dementia. deficits during dementia. Journal of Neural Transmission, 111Journal of Neural Transmission, 111, 235-245., 235-245.

• Menon, V., & Levitin, D. J. (2005). The rewards of music listening: Response and physiological connectivity Menon, V., & Levitin, D. J. (2005). The rewards of music listening: Response and physiological connectivity of the mesolimbic system [Electronic version]. of the mesolimbic system [Electronic version]. NeuroimageNeuroimage

Page 39: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

References – Neurological References – Neurological Aspects of Activity (continued).Aspects of Activity (continued).• Mirz, F., Ovesen, T., Ishizu, K., Johannsen, P., Madsen, S., Gjedde, A., et al. (1999). Stimulus-dependent Mirz, F., Ovesen, T., Ishizu, K., Johannsen, P., Madsen, S., Gjedde, A., et al. (1999). Stimulus-dependent

central processing of auditory stimuli: A PET study [Electronic version]. central processing of auditory stimuli: A PET study [Electronic version]. Scandinavian Audiology, 28Scandinavian Audiology, 28(3), (3), 161-169.161-169.

• Mobbs, D., Greicius, M. D., Abdel-Azim, E., Menon, V., & Reiss, A. L. (2003). Humor modulates the Mobbs, D., Greicius, M. D., Abdel-Azim, E., Menon, V., & Reiss, A. L. (2003). Humor modulates the mesolimbic reward centers [Electronic version]. mesolimbic reward centers [Electronic version]. Neuron, 40,Neuron, 40, 1041-1048. 1041-1048.

• Naranjo, C. A., Tremblay, L. K., & Busto, U. E. (2001). The role of the brain reward system in depression Naranjo, C. A., Tremblay, L. K., & Busto, U. E. (2001). The role of the brain reward system in depression [Electronic version]. [Electronic version]. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 25Progress in Neuro-Psychopharmacology and Biological Psychiatry, 25, 781-823., 781-823.

• National Science Board. (1998). National Science Board. (1998). Science and engineering indicatorsScience and engineering indicators. Washington: National Science Board.. Washington: National Science Board.• Nestler, E. J., Barrot, M., DiLeone, R. J., Eisch, A. J., Gold, S. J., & Monteggia, L.. M. (2002). Neurobiology of Nestler, E. J., Barrot, M., DiLeone, R. J., Eisch, A. J., Gold, S. J., & Monteggia, L.. M. (2002). Neurobiology of

depression [Electronic version]. depression [Electronic version]. Neuron, 34Neuron, 34, 13-25., 13-25.• Newberg, A., Alavi, A., Baime, M., Poudehnad, M., Santanna, J., & d’Aquili, E. (2001). The measurement of Newberg, A., Alavi, A., Baime, M., Poudehnad, M., Santanna, J., & d’Aquili, E. (2001). The measurement of

regional cerebral blood flow during the complex cognitive task of meditation: A preliminary SPECT study. regional cerebral blood flow during the complex cognitive task of meditation: A preliminary SPECT study. Psychiatry Research, 106Psychiatry Research, 106, 113-122., 113-122.

• Ohnishi, T., Matsuda, H., Asada, T., Aruga, M., Hirakata, M., Nishikawa, M., et al. (2001). Functional Ohnishi, T., Matsuda, H., Asada, T., Aruga, M., Hirakata, M., Nishikawa, M., et al. (2001). Functional anatomy of musical perception in musicians. anatomy of musical perception in musicians. Cerebral Cortex, 11Cerebral Cortex, 11, 754-760., 754-760.

• Papp, M., Klimek, V., & Willner, P. (1994). Parallel changes in dopamine D2 binding in limbic forebrain Papp, M., Klimek, V., & Willner, P. (1994). Parallel changes in dopamine D2 binding in limbic forebrain associated with chronic mild stress-induced anhedonia and its reversal by imipramine. associated with chronic mild stress-induced anhedonia and its reversal by imipramine. Psychopharmacology, 115Psychopharmacology, 115, 441-446., 441-446.

• Paus, T., & Barrett, J. (2004). Transcranial magnetic stimulation (TMS) of the human frontal cortex: Paus, T., & Barrett, J. (2004). Transcranial magnetic stimulation (TMS) of the human frontal cortex: Implications for repetitive TMS treatment of depression. Implications for repetitive TMS treatment of depression. Journal of Psychiatry and Neuroscience, 29Journal of Psychiatry and Neuroscience, 29, 268—, 268—279.279.

• Popkess-Vawter, S. (1986). Tapping into your alpha rhythm: My painting hobby. Popkess-Vawter, S. (1986). Tapping into your alpha rhythm: My painting hobby. The Kansas Nurse, 61The Kansas Nurse, 61(7), (7), 5-6.5-6.

• Potenza, M. N., & Wilber, M. K. (2001). Neuroimaging studies of pathological gambling and substance Potenza, M. N., & Wilber, M. K. (2001). Neuroimaging studies of pathological gambling and substance dependence [Electronic version]. dependence [Electronic version]. Psychiatric TimesPsychiatric Times, 18(10)., 18(10).

• Rahe, R. H. (1964). Social stress and illness onset. Rahe, R. H. (1964). Social stress and illness onset. Journal of Psychosomatic Research, 8Journal of Psychosomatic Research, 8, 35-44., 35-44.

Page 40: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

References – Neurological References – Neurological Aspects of Activity (continued).Aspects of Activity (continued).• Riley, K. P., Snowdon, D. A., Desrosiers, M. F., & Markesbery, W. R. (2005). Early life linguistic ability, late life Riley, K. P., Snowdon, D. A., Desrosiers, M. F., & Markesbery, W. R. (2005). Early life linguistic ability, late life

cognitive function, and neuropathology: Findings from the Nun Study [Electronic version]. cognitive function, and neuropathology: Findings from the Nun Study [Electronic version]. Neurobiology of Neurobiology of Aging, 26Aging, 26, 341-347., 341-347.

• Ritskes, R., Ritskes-Hoitinga, M., Stodkilde-Jorgensen, H., Baerntsen, K., & Hartman, T. (2003). MRI scanning Ritskes, R., Ritskes-Hoitinga, M., Stodkilde-Jorgensen, H., Baerntsen, K., & Hartman, T. (2003). MRI scanning during Zen meditation: The picture of enlightenment? during Zen meditation: The picture of enlightenment? Constructivism in the Human Sciences, 8Constructivism in the Human Sciences, 8(1), 85-90.(1), 85-90.

• Sacchett, C. (2002). Drawing in aphasia: Moving towards the interactive [Electronic version]. Sacchett, C. (2002). Drawing in aphasia: Moving towards the interactive [Electronic version]. International International Journal of Human-Computer Studies, 57Journal of Human-Computer Studies, 57, 263-277., 263-277.

• Seligman, M. E. P. (1975). Seligman, M. E. P. (1975). Helplessness: On depression, development, and deathHelplessness: On depression, development, and death. San Francisco: W. H. . San Francisco: W. H. Freeman.Freeman.

• Selye, H. (1976). Selye, H. (1976). The stress of lifeThe stress of life. New York: McGraw-Hill.. New York: McGraw-Hill.• Seung, Y., Kyong, J. S., Woo, S. H., Lee, B. T., & Lee, K. M. (2005). Brain activation during music listening in Seung, Y., Kyong, J. S., Woo, S. H., Lee, B. T., & Lee, K. M. (2005). Brain activation during music listening in

individuals with or without prior music training [Electronic version]. individuals with or without prior music training [Electronic version]. Neuroscience Research, 52Neuroscience Research, 52, 323-329., 323-329.• Scarmeas, N., Levy, R. B., Tang, M. X., Manly, J., & Stern, Y. (2001). Influence of leisure activity on the Scarmeas, N., Levy, R. B., Tang, M. X., Manly, J., & Stern, Y. (2001). Influence of leisure activity on the

incidence of Alzheimer’s disease [Electronic version]. incidence of Alzheimer’s disease [Electronic version]. Neurology, 57Neurology, 57, 2236-2242., 2236-2242.• Skuse, D., Morris, J., & Lawrence, K. (2003). The amygdala and development of the social brain. Skuse, D., Morris, J., & Lawrence, K. (2003). The amygdala and development of the social brain. Annals of the Annals of the

New York Academy of Science, 10008New York Academy of Science, 10008, 91-101., 91-101.• Small, D. M., Zatorre, R. J., Dagher, A., Evans, A. C., Jones-Gotman, M. (2001). Changes in brain activity Small, D. M., Zatorre, R. J., Dagher, A., Evans, A. C., Jones-Gotman, M. (2001). Changes in brain activity

related to eating chocolate: From pleasure to aversion [Electronic version]. related to eating chocolate: From pleasure to aversion [Electronic version]. Brain, 124Brain, 124, 1720-1733., 1720-1733.• Snowdown, D. A., Grenier, L. H., & Markesbery, W. R. (2000). Linguistic ability in early life and the Snowdown, D. A., Grenier, L. H., & Markesbery, W. R. (2000). Linguistic ability in early life and the

neuropathology of ALzherimer’s disease and cerebrovascular disease. Findings from the Nun Study neuropathology of ALzherimer’s disease and cerebrovascular disease. Findings from the Nun Study [Electronic version]. [Electronic version]. Annals of the New York Academy of Science, 903Annals of the New York Academy of Science, 903, 34-38., 34-38.

• Snowdon, D. A., Greiner, L. H., Mortimer, J. A., Riley, K. P., Greiner, P. A., & Markesbury, W. R. (1997). Brain Snowdon, D. A., Greiner, L. H., Mortimer, J. A., Riley, K. P., Greiner, P. A., & Markesbury, W. R. (1997). Brain infarction and the clinical expression of Alzheimer’s disease: the Nun Study. infarction and the clinical expression of Alzheimer’s disease: the Nun Study. Journal of the American medical Journal of the American medical Association, 277Association, 277, 813-817., 813-817.

• Snowdon, D. A., Kemper, S. J., Mortimer, J. A., Greiner, L. H., Wekstein, D. R., & Markesbery, W. R. (1996a). Snowdon, D. A., Kemper, S. J., Mortimer, J. A., Greiner, L. H., Wekstein, D. R., & Markesbery, W. R. (1996a). Linguistic ability in early life and cognitive function in late life: Findings from the Nun Study. Linguistic ability in early life and cognitive function in late life: Findings from the Nun Study. Journal of the Journal of the American medical Association, 275American medical Association, 275, 528-532., 528-532.

Page 41: The Power of Activity in Rehabilitation Victoria Schindler, PhD, OTR, BCMH, FAOTA Richard Stockton College of NJ New Jersey Occupational Therapy Association.

References – Neurological References – Neurological Aspects of Activity (continued).Aspects of Activity (continued).• Snowdon, D. A., Kemper, S. J., Mortimer, J. A., Greiner, L. H., Wekstein, D. R., & Markesbery, W. R. Snowdon, D. A., Kemper, S. J., Mortimer, J. A., Greiner, L. H., Wekstein, D. R., & Markesbery, W. R.

(1996b). Linguistic ability in early life and cognitive function and Alzheimer’s disease in late life. (1996b). Linguistic ability in early life and cognitive function and Alzheimer’s disease in late life. Findings from the Nun Study. Findings from the Nun Study. Journal of the American Medical Association, 275Journal of the American Medical Association, 275, 1879., 1879.

• Teasdale, J. D., Segal, Z. V., Wiiliams, J. M. G., Ridgeway, V. A., Soulsby, J. M., & Lau, M. A. (2000). Teasdale, J. D., Segal, Z. V., Wiiliams, J. M. G., Ridgeway, V. A., Soulsby, J. M., & Lau, M. A. (2000). Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Journal of Counseling and Clinical Psychology, 68Journal of Counseling and Clinical Psychology, 68, 615-623., 615-623.

• Tessitore, A., Hariri, A. R., Fera, F., Smith, W. G., Chase, T. N., Hyde, T. M., et al. (2002). Dopamine Tessitore, A., Hariri, A. R., Fera, F., Smith, W. G., Chase, T. N., Hyde, T. M., et al. (2002). Dopamine modulates the response of the human amygdala: A study in Parkinson’s disease [Electronic version]. modulates the response of the human amygdala: A study in Parkinson’s disease [Electronic version]. Journal of Neuroscience, 22Journal of Neuroscience, 22, 9099-9103., 9099-9103.

• Verghese, J., Lipton, R. B., Katz, M. J., Hall, C. B., Derby, C. A., Kuslansky, G., et al. (2003). Leisure Verghese, J., Lipton, R. B., Katz, M. J., Hall, C. B., Derby, C. A., Kuslansky, G., et al. (2003). Leisure activities and the risk of dementia in the elderly [Electronic version]. activities and the risk of dementia in the elderly [Electronic version]. New England Journal of New England Journal of Medicine, 348Medicine, 348, 2508-2516., 2508-2516.

• Volkow, N. D., & Fowler, J. S. (2000). Addiction, a disease of compulsion and drive: Involvement of Volkow, N. D., & Fowler, J. S. (2000). Addiction, a disease of compulsion and drive: Involvement of the orbitofrotnal cortex. the orbitofrotnal cortex. Cerebral Cortex, 10Cerebral Cortex, 10, 318-325., 318-325.

• Volkow, N. D., Wang, G. J., Fowler, J. S., Hitzemann, R., Angrist, B., Gatley, S. J., et al. (1999). Volkow, N. D., Wang, G. J., Fowler, J. S., Hitzemann, R., Angrist, B., Gatley, S. J., et al. (1999). Association of methylphenidate-induced craving with changes in right striato-orbitofrontal Association of methylphenidate-induced craving with changes in right striato-orbitofrontal metabolism in cocaine abusers: Implications in addiction. metabolism in cocaine abusers: Implications in addiction. American Journal of Psychiatry, 156American Journal of Psychiatry, 156, 9-26., 9-26.

• Williams, K. A., Kolar, M. M., Reger, B. E., & Pearson, J. C. (2001). Evaluation of a wellness-bases Williams, K. A., Kolar, M. M., Reger, B. E., & Pearson, J. C. (2001). Evaluation of a wellness-bases mindfulness stress reduction intervention: A controlled trial. mindfulness stress reduction intervention: A controlled trial. American Journal of Health Promotion, American Journal of Health Promotion, 1515, 422-432., 422-432.

• Williams, R., & Williams, V. (1993). Williams, R., & Williams, V. (1993). Anger killsAnger kills. New York: Random House.. New York: Random House.• Wilson, R. S., Mendes de Leon, C. F., Barnes, L., Schneider, J., Bienias, J. L., Evans, D. A., et al. Wilson, R. S., Mendes de Leon, C. F., Barnes, L., Schneider, J., Bienias, J. L., Evans, D. A., et al.

(2002). Participation in cognitively stimulating activities and risk of incident Alzheimer’s disease. (2002). Participation in cognitively stimulating activities and risk of incident Alzheimer’s disease. Journal of the American Medical Association, 287Journal of the American Medical Association, 287, 742-748., 742-748.