The plasma jet that heals wounds

Certi fi ed as medical device (IIa).

neoplas tools GmbH Walther-Rathenau-Str. 49a 17489 Greifswald / Germany

CEO:Dr. Christi an Theel / Alexander Beckerphone: +49 3834 515 211 / +49 3834 515 213fax: +49 3834 515 209 info@neoplas-tools.eu

more Informati on:www.neoplas-tools.euVersion 2.1

Benefi ts• supports wound healing• anti -bacterial and anti -infl ammatory eff ect, deacti vates multi -resistant pathogens• wide range of indicati ons for acute and chronic wounds• painless non-invasive procedure that does not require anesthesia• precise applicati on even in recesses and caviti es• easy handling • can be delegated by att ending physician• no side eff ects or formati on of resistances observed

Manufacturerneoplas tools GmbH is a spin-off of the Leib-niz- Insti tute for Plasma Science and Technolo-gy (INP Greifswald). Since 2013 our company has been following an innovati ve approach to establish the applicati on of cold physical plasma via a jet procedure as a new therapy method in medicine. Together with science we are working conti nuously on the further deve-lopment of cold plasma therapy soluti ons in medical technology.

We are a partner of the Gesundheitsnetz Mit-telsachsen (health network of Central Saxony), member of the Nati onales Zentrum für Plas-mamedizin e. V. (German plasma research net-work) and part of the BioCon Valley® network, and we are in cooperati on with the university hospitals of Greifswald, Berlin, Kiel, Hamburg, Mainz, Erlangen and many more.

The therapy is performed as a supplement to the standard wound management.

kINPen® MED is the fi rst CE certi fi ed atmospheric pressure plasma jet with a medical device approval for the treatment of chronic wounds and pathogen-induced diseases of the skin.

This new and eff ecti ve type of treatment supports wound healing and has proven to be an eff ecti ve supplement to standard wound management.

The plasma jet delivers physical cold plasma with a temperature of ca. 37 degrees Celsius (98.6 degrees Fahrenheit) to the wound with pinpoint accuracy. Areas with complex surface structures, recesses and caviti es are easy to reach with the jet and can be treated evenly. The inert gas argon used for the plas-ma generati on guarantees a permanently consistent and stable atmosphere round the generated plasma jet, providing an invariably high treatment quality.

This innovati on is a result of the longstanding scien-ti fi c cooperati on with the Leibniz-Insti tute for Plas-ma Science and Technology (INP Greifswald), the

Applicati onThe kINPen® MED is moved perpendicularly ac-ross the aff ected wound area with a moderate consistent speed of ca. 5 mm/s. The eff ecti ve plas-ma area of the kINPen® MED covers about 1 cm2.During the treatment, maintenance of the spe-cifi ed distance and hygiene is ensured by an ex-changeable spacer. The intensity of the treatment is controlled via the treatment ti me and should amount to 30-60 s/cm2.

The treatment can be performed in one-day to three-day intervals as long as there are no side ef-fects. The overall durati on of the cold plasma the-rapy depends on the individual wound conditi ons and the treatment frequency. The therapy is per-formed as a supplement to the standard wound management. Prior to the plasma treatment ne-croti c wounds have to undergo debridement. The plasma treatment should be performed before topical medicati on to avoid undesired interacti ons with anti septi cs. Due to its simple operati on the applicati on of the kINPen® MED plasma jet can be delegated by the att ending physician.

Universitätsmedizin Greifswald (university hospital Greifswald), the Charité Universitätsmedizin Berlin (Charité university hospital Berlin) and several part-ners in industry.

Mode of acti onCold plasma therapy is based on a purely physical ef-fect. The major components of plasma are light inten-sity UV radiati on, reacti ve oxygen and nitrogen spe-cies, electromagneti c fi elds and a short-term increase of temperature. These modes of acti on kill germs, including a large number of microorganisms and bac-teria strains and multi -resistant pathogens. Tissue regenerati on is sti mulated even in the deeper skin layers and microcirculati on is supported, resulti ng in an improved oxygen and nitrogen supply. Therapy with the kINPen® MED off ers a combinati on of the positi ve properti es of the diff erent modes of acti on.

Indicati onsThe kINPen® MED is parti cularly well suited for the treatment of wounds that are chronic, infected or that heal badly, for example in the presence of ulcus cruris or decubitus ulcer, and pathogen-induced skin or nail disorders (e. g. acne vulgaris or ti nea pedis). Clinical research is currently focusing on an exten-sion of the scope of indicati ons.

The kINPen® MED is user-friendly and can be used mobile in treatment room

mehr Informati onen fi nden Sie unter:www.neoplas-tools.eu

This new and eff ecti ve cold plasma therapy supports wound healing and has proven to be an eff ecti ve supplement to standard wound management.