The Nuts and Bolts of Lyme Disease PreventionLaura Badeski

Oral Vaccinations of Sciurus carolinensis to

Reduce the Prevalence of Lyme borreliolis

Vector-Borne DiseaseSpread by Borrelia burgdoferi

Lyme Disease

Transmission Cycle

Lyme Disease Prevention

Protective clothing

Reduce host populations

Lyme Disease Prevention

Apply acaracides on hosts

Developed by SmithKline BeechamStimulates antibodies against OspA76% effective

LYMErix Vaccine

Vaccine available 1998-2002Speculated to cause arthritis

OspA to be used as an ecologicalprevention method

Theory

Recycles past researchRelatively low-risk

Objectives

Determine efficacy of OspA vaccineReduce B. burdorferi in Eastern Grey squirrels & ticksDecrease Lyme disease prevalence

White-footed mice vs.Eastern grey squirrels

Decrease B. burgdorferiDecrease Lyme disease

Hypothesis

Methods

Methods

Methods

Methods

Lyme disease prevalence survey

Drag sampling

Significance

Significance