The Mexican approach to conduct non-myeloablative stem cell … · 2020-05-01 · Donor selection...
Transcript of The Mexican approach to conduct non-myeloablative stem cell … · 2020-05-01 · Donor selection...
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Donor selection
Haplo versus cord
Resource limited environment
Donor registries
Domestic versus international
donor registries
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Haplo versus cord
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Placental blood
Four domestic public banks
Several private banks
Expensive cords from abroad (NMDP)
Poor quality of the domestic cords
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Placental blood
Domestic cord: 3 000 USD
Imported cord: 30 000 USD
Restrictive
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2006
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68 placental blood allografts
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Haploidentical allografts
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vs
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Hematology 2013, in the press
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18 haploidentical allografts
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cords
haplos
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Haplos versus cords
Similar long term results
Haplos are cheaper (Cy)
No cord blood banks
More realistic in
underprivileged circumstances
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Resource limited
environment
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Centers participating in the CIBMTR 2011
SUM-WW11_2.ppt
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BBMT 2009; 15:1628
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Traditional Mexican approach
Impossible
Impossible
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++
Possible
Possible
+ / -
+
30 – 50%
300 000 USD
Difficult
17 %
20 000 USD
Possible
Self-recovery
Outpatient
Transfusions
GVHD
100-day mortality
Cost
Developing countries
Allografts
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Donor registries
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Donor registries
Domestic: DONORMO
• Less than efficient
• Transplant center restricted
• Expensive
International
• CRIR
• NMDP
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….. this is the end-result of
sodality and friendship, two
uncommon values in a culture
driven by rivalry, jealousy,
disqualification, economic interest
and the zeal to reach that vacuum
known as success……
Julio Glockner