F. Stratton, D. S. Smith, and V. L Rawlinson

Kochwa, S., and Rosenfield, R. E. (1964). J. Immunol., 92, 682.Laurell, A. B., and Siboo, R. (1966). Acta path. microbiol. scand., 68,

230.Mehrotra, T. N. (1960). Immunology, 3, 265.-, and Charlwood, P. A. (1960). Ibid., 3, 254.Polley, M. J., Adinolfi, M., and Mollison, P. L. (1963). Vox Sang

(Basel), 8, 385.Schultze, H. E., and Heremans, J. F. (1966). Molecular Biology of

Human Proteins, vol. 1, p. 227. Elsevier, Amsterdam.

Stratton, F., Gunson, H. H., and Rawlinson, V. 1. (1962). Trans-fusion, 2, 135.

(1965). Ibid., 5, 216.-, and Rawlinson, V. I. (1965). Brit. J. Haemat., 11, 592.-. To be published.

-, and Renton, P. H. (1958). Practical Blood Grouping. Blackwell,Oxford.

, Smith, D. S., and Rawlinson, V. I. (1968). Clin. exp. Immunol.,3, 81.

The September 1968 IssueTHE SEPTEMBER 1968 ISSUE CONTAINS THE FOLLOWING PAPERS

Biochemical consequences of chronic renal failure: Areview M. R. WILLS

Water, sodium, potassium, and chloride content ofskeletal muscle in fit and ill subjects C. T. G. FLEAR,IRENf FLORENCE, and J. A. WILLIAMS

Binding of neomycin and analogues by fatty acids invitro R. W. LACEY

Modified colorimetric ultramicro method for estimatingNefa in serum M. C. ELPHICK

Cystinosis: electron microscopic evidence of lysosomalstorage of cystine in lymph node A. D. PATRICK andB. D. LAKE

An immunofluorescence method for the diagnosis ofprimary syphilis using an absorption technique M. F.GARNER and J. H. ROBSON

Histochemical investigation of acid mucosubstances insecondary amyloidosis C. A. PENNOCK, J. BURNS, andG. MASSARELLA

Chemical and histochemical characterization of muco-polysaccharides in a jaw myxoma J. J. HODSON andR. E. S. PROUT

Coexistence of pernicious anaemia and acute erythraemicmyelosis E. M. RIDDELL and R. J. L. DAVIDSON

Determination of vitamin B12 absorption by a simplewhole body counter N. D. C. FINLAYSON, D. J. C.SHEARMAN, J. D. SIMPSON, and R. H. GIRDWOOD

Prophylactic folic acid in women with pemicious anaemiapregnant after infertility MARION HALL and RONALD J. L.DAVIDSON

Serum iron, total iron-binding capacity, and percentagesaturation in normal subjects R. SINNIAH and D. W.NEILL

Intravenous iron-dextran: studies on unsaturated iron-binding capacity J. S. G. COX, G. F. MOSS, I. BREMNER,and JANET REASON

Cytochrome oxidase activity in the gastric mucosa ofpatients with iron deficiency W. D. STONE

Role of lipoproteins in the formation of spur cell anaemiaMANUEL MARTINEZ-MALDONADO

Autoimmune haemolytic anaemia associated withovarian dermoid cyst L. R. I. BAKER, M. C. BRAIN, J. G.AZZOPARDI, and s. M. WORLLEDGE

Horse agglutinins in infectious mononucleosis. IIICriterion for differential diagnosis C. L. LEE, F. ZANDREW,and I. DAVIDSOHN

Factor VIII and antibody levels in plasma fractionsprepared by cryoprecipitation ANDREW POLLOCK

Latex-bound antifibrinogen test for plasma fibrinogenassay D. J. CASTELAN, J. HIRSH, and M. MARTIN

Lipid content of malignant lymphomas D. H. WRIGHT

Survey of the eventual diagnosis in 600 cases referred fora second histological opinion after an initial biopsydiagnosis of Hodgkin's disease W. ST. C. SYMMERS,SENR.

Survey of the eventual diagnosis in 226 cases referred fora second histological opinion after an initial biopsydiagnosis of reticulum cell sarcoma W. ST. C. SYMMERS,SENR.

Labial salivary gland biopsy in Sj6gren's disease D. M.CHISHOLM and D. K. MASON

Plasmacytoma of the thyroid J. R. S. MORE, D. W.DAWSON, A. J. RALSTON, and ISLA CRAIG

Technical methodsPotentiometric method for the determination of inorganicfluoride in biological material F. W. BARNES and j.RUNCIE

Quick-drying sterile cabinet for culture plates P. N.EDMUNDS

A custom-built hospital blood bank D. G. CHALMERS

Letter to the Editor

Book reviews

Notices

Copies are still available and may be obtained from the PUBLISHING MANAGER

BRITISH MEDICAL ASSOCIATION, TAVISTOCK SQUARE. w.c.1, price 18s. 6D.

714

Residualformaldehyde after low-temperature, steam, andformaldehyde sterilization

occurs in blankets treated with steam and formalde-hyde and then stored (Alder, 1968). The residuallevels in paper might be used in the storage ofgoods from central sterilization departments, forexample, to play a similar self-disinfecting role inpaper bags and wraps. A small injection of formal-dehyde vapour into the chamber during autoclavingmight be of value in this respect.The method used to recover the chemicals by

aqueous extraction does, we feel, give meaningfulresults but we cannot, except by a method such assteam distillation or reflux, claim to have extractedfrom any article all of such chemicals absorbed intoor combined with it. However, the results obtainedby aqueous extraction represent a major proportionof the total which could be extracted by refluxing. Inany case the level of recovered formaldehyde orethylene oxide obtained by aqueous extraction maywell bear a closer relation to the levels likely to befound in use in vivo when aqueous solutions arepassed through tubing into a patient, or the tubingor other article is inserted into a patient and sur-rounded by aqueous solutions. The solubility ofboth ethylene oxide and formaldehyde in water is

high compared with the levels obtained in the aqueousextractions and enables us to discount this factorin comparisons.We consider that in rubber and plastic articles,

residual levels of formaldehyde following the low-temperature steam and formaldehyde sterilizationprocess are not likely to be toxic to patients. Theyare certainly much lower than the ethylene oxidelevels we obtained following sterilization by thatgas. In fabric and paper the higher formaldehydelevels may in fact be of value as they may give acontinuing self-disinfecting effect during storage.

REFERENCES

Alder, V. G. (1968). Cospar Technical Bulletin (in the press).-, Brown, A. M., and Gillespie, W. A. (1966). J. clin. Path., 19, 83.Blohm, S. G. (1959). Acta derm.-venereol. (Stockh.), 39, 450.Critchfield, E. E., and Johnson, J. B. (1957). Anal. Chem., 29, 797.Dickinson, J. C., and Wagg, R. E. (1967). J. Appl. Bact., 30, 340.Gibson, G. L., Johnston, H. P. (1967). Brit. IHosp. J. and Soc. Sci.

Rev., 77, 1208.Gillespie, W. A., and Alder, V. G. (1957). Lancet, 1, 632.-, , Ayliffe, G. A. J., Bradbeer, J. W., and Wypkema, W.

(I959). Ibid., 2, 781.Kelsey, J. C. (1963). J. clin. Path., 16, 542.Marcussen, P. V. (1959). Acta derm.-venereol. (Stockh.), 39, 348.Wereide, K. (1964). Acta allerg. (Kbh), 19, 351.

Reports and Bulletins prepared by the Association of Clinical BiochemistsThe following reports and bulletins are published by the Association of Clinical Biochemists. They may be obtainedfrom The Administrative Office, Association of Clinical Biochemists, 7 Warwick Court, Holborn, London, W.C.1.The prices include postage, but airmail will be charged extra.

SCIENTIFIC REPORTS

1 Colorimeters with Flow Through Cells. A criticalassessment of 4 instruments. 1965. P. M. G.BROUGHTON and c. RILEY. 13s. 6d.

2 Colorimeters. A critical assessment of 5 commercialinstruments. 1966. P. M. G. BROUGHTON, C. RILEY,J. G. H. COOK, P. G. SANDERS, and H. BRAUNSBERG. 15s.

3 Automatic Dispensing Pipettes. An assessment of 35commercial instruments. 1967. P. M. G. BROUGHTON,A. H. GOWENLOCK, G. M. WIDDOWSON, and K. A.AHLQUIST. I OS.

TECHNICAL BULLETINS

9 Determination of Urea by AutoAnalyzer. November1966. RUTH M. HASLAM. 2s. 6d.

10 Filter Fluorimeters. A comparative list of 14 in-struments. March 1967. HANNELORE BRAUNSBERG.5s.

11 Determination of Serum Albumin by AutoAnalyzerusing Bromocresol Green. October 1967. B. E.NORTHAM and G. M. WIDDOWSON. 2s. 6d.

12 Control Solutions for Clinical Biochemistry. February1968. P. M. G. BROUGHTON. 2s. 6d.

13 An Assessment of the Technicon Type II SamplerUnit. March 1968. B. C. GRAY and G. K. MCGOWAN.Is. 6d.

14 Atomic Absorption Spectroscopy. An Outline of itsPrinciples and a Guide to the Selection of Instru-ments. May 1968. J. B. DAWSON and P. M. G.BROUGHTON. 4s.

15 A Guide to Automatic Pipettes (2nd edition). June1968. P. M. G. BROUGHTON. 5s.

775

Index to Volume XXIAbbreviations:-'(P)' refers to the summaries of papers read at the

General Meetings of the Association of Clinical Pathologists.'(L)' refers to letters to the Editor.

Acid mucosubstances in secondary amyloidosis, histochemicalinvestigaton of, 578

Acidosis in chronic renal failure, 544ACKERLEY, A. G.: A post-partum circulating anticoagulant (P), 539ACLAND, J. D., and STRONG, R.: Comparison between a microdiffusion

and an ion exchange method for the determination of plasmaammonium, 12

Activation analysis, neutron, for copper in Wilson's disease, 8Agglutir9ins, horse, for differential diagnosis of infectious mono-

nucleosis, 631Alcohol, determination in plasma, urine:whole blood and urine:

plasma ratios for (P), 794ALEXANDER, M. K. See ALLAN, R. N., and ALEXANDER, M. K.ALLAN, R. N., and ALEXANDER, M. K.: A sex difference in the leucocyte

count, 691Alpha2-macroglobulin, serum levels in disease, 27Ammonium, plasma, determination of, comparison between micro-

diffusion and ion exchange methods, 12-,--, improved ion exchange method for, 14

Amylase determination with dimethylsulphoxide starch solution, 764Amyloidosis and primary 'acquired' hypogammaglobulinaemia, 32-, secondary, acid mucosubstances in, histochemical investigation of,

578Anaemia, haemolytic, autoimmune, associated with ovarian dermoid

cyst, 626-, Heinz body, congenital, due to haemoglobin Hammersmith(P), 540

-,-, microangiopathic (P), 793-, megaloblastic, of pregnancy, clinical and laboratory study (P),

540-, pernicious, cellular defect in, investigation of (P), 792- -, combined with acute erythraemic myelosis, 590-' -, folic acid prophylaxis in women pregnant after periods of

infertility with, 599-, spur cell, role of lipoproteins in formation of, in cirrhosis of

liver, 620ANDERSON, B. B., and COWAN, J. D.: Effect of light on the Lactobacillus

casei microbiological assay, 85Aneurysm, congenital or berry, in optic nerve, 335Antibiotics, absorption during peritoneal dialysis in c6.ronic renal

failure, 88-, resistance of coagulase-negative staphylococci and micrococci to,

722-, sensitivity of Bacteroides fragilis to, in vitro study, 432Antibodies, blood group, analysis by gel filtration on Sephadex

G-200, 708-, intestinal, in ulcerative colitis (P), 536Antibody and factor VIII levels in plasma fractions prepared by

cryoprecipitation, 635-, circulating, in human Toxocara infections, detection by indirect

fluorescent antibody test, 449Anticoagulant, circulating, post-partum (P), 539- therapy, long-term, partial thromboplastin time test in (P), 539Antifibrinogen test, latex-bound, for plasma fibrinogen assay, 638Appendix, argentaffin and non-argentaffin carcinoid tumours of, 60ARTHUR, J. F.: Structure and significance of metaplastic nodules in

the rectal mucosa, 735Asbestos, quantitation in tissue (P), 537Ascaris antigen in filarial complement-fixation test for pulmonary

tropical eosinophilia, 394Aspergillosis (P), 539Association of Clinical Biochemists: Reports and Bulletins, 106, 212,

420, 510, 637, 775Association of Clinical Pathologists: Data processing in clinical

pathology (Report of a Working Party), 231-301-: 80th General Meeting, 536-: 81st General Meeting, 791

Atrium, left, giant cell myocarditis limited to, with mitral stenosis,750

Australia, South, Plesiomonas shigelloides in, 715AutoAnalyzer SMA-4, determination of haematocrit with (L), 114,

533-, Technicon, evaluation for automating complement-fixation tests,

521AZZOPARDI, J. G. See BAKER, L. R. I., BRAIN, M. C., AZZOPARDI, J. G.,

and WORLLEDGE, S. M.

Bacteria, growth from blood cultures, effect of dilution, 719-, plating out on solid medium, rotary machine for, 784Bacteriuria, detection by dip-inoculum transport medium spoon

method in women at antenatal clinics, 445795

-, significant, nitrite test kit (Strat-test) for detection of, evaluationof, 443

Bacteroides fragilis, sensitivity to antibiotics of, in vitro study, 432BAKER, L. R. I., BRAIN, M. C., AZZOPARDI, J. G., and WORLLEDGE, S. M.:

Autoimmune haemolytic anaemia associated with ovariandermoid cyst, 626

BAMBURY, J. M. See WILLIAMS, R. F., and BAMBURY, J. M.Bantu, storage iron in muscle cells and tissue histiocytes in, 495Barlow, Percy Lazarus-. See Lazarus-Barlow, Percy.BARNES, F. W., and RUNCIE, J.: Potentiometric method for the deter-

mination of inorganic fluoride in biological material, 668BARNES, H. D., HURWORTH, E., and MILLAR, J. H. D.: Erythropoietic

porphyrin hepatitis, 157BARRY, M.: Determination of chelated iron in the urine, 166-, and CARTEI, G. C.: Estimation of ferrioxamine in jaundiced urine,

169BARSON, A. J., JONES, A. w., and LODGE, K. V.: Pulmonary blastoma,

480BENNETT, P. N.: Role of erythrocytes in the acute platelet response to

operation, 695Benzidine test for occult blood in stools, effect of oral iron prepara-

tions, 41Benzylpenicillin, resistance of penicillinase-forming strains of Staph.

aureus and penicillinase-negative variants to, 75BEIrELHEIM, K. A. See HUGHES, M. H., GREAVES, J. L., and BETTELHEIM,

K. A.BIELAWIEC, M. See CHAKRABARTI, R., BIELAWIEC, M., EVANS, J. F., and

FEARNLEY, G. R.BIGGS, R. See DENSON, K. W. E., BIGGS, R., and MANNUCCI, P. M.Bilirubin, serum, determination of, automated method for, 196-, unconjugated, effect on estimation of serum iron by modified

Sanford technique, 776Biopsy, liver, adult, tissue culture of (P), 793-,-, method for obtaining both frozen and paraffin sections from,

413-, renal, electron microscopy of (P), 793BIRD, R., and BURR, R. G.: A paper test for occult blood in faeces

using ortho-dianisidine (L), 675BISSERU, B., and WOODRUFF, A. W.: The detection of circulating

antibody in human toxacara infections using the indirectfluorescent antibody test, 449

BLACKBURN, E. K. See BRONKS, I. G., and BLACKBURN, E. K.Bladder, urinary, contiguous but dissimilar epithelial neoplasms of,

332Blastoma, pulmonary, 480Blood bank, hospital, specially-designed, 673- cells, mean corpuscular and packed cell volumes, measurement

with Coulter counter, 222-clot lysis time, dilute, for determination of fibrinolytic activity,

micro modification of, 780- cultures, growth of bacteria from, effect of dilution, 719- donors, male, storage iron depletion in, and iron status in women,

402, effect on 6-phosphogluconate dehydrogenase assay in vaginalfluid, 189

-group antibodies, analysis by gel filtration on Sephadex G-200,708

-, occult, in faeces, benzidine test for, effect of oral iron preparations,41-, - -, ortho-dianisidine paper test for (L), 675

-platelets, acute response to operation of, role of erythrocytes in,695

--, adhesiveness of, effect of centrifugation on measurement inplatelet-rich plasma, 397

--, aggregation, effect of fibrinogen degradation products, 147--, levels, effect of iniected heparin, 55-, pyruvic and lactic acids in, determination by automated enzymatic

fluorometric method, 171BOLTON, F. G. See PENNOCK, C. A., PASSANT, L. P., and BOLTON, F. G.Bone lesions in chronic renal failure, 545- marrow. See MarrowBook reviews:Adams, C. M. W.: Vascular Histochemistry, 1967, 228Amromin, G. D.: Pathology ofLeukemia, 1968 .787Batsakis, J. G., and Briere, J. G.: Interpretive Enzymology, 1967

679Berenblum, I.: Cancer Research Today, 1967, 230Bouchier, I. A. D., and Billing, B. H., eds.: Bilirubin Metabolism,

1967, 117Brooke, B. B., and Slaney, G.: Metabolic Derangements in Gastro-

intestinal Surgery, 1966, 116

796 Index

Broughton, P. M. G., Gowenlock, A. H., Widdowson, G. M., andAhlquist, K. A.: Automatic Dispensing Pipettes: An Assessmentof 35 Commercial Instruments (Association of Clinical Bio-chemists, Scientific Report, No. 3), 1967, 417

Bullough, W. S.: The Evolution of Differentiation, 1967, 678Camps, F. E., ed.: Gradwohl's Legal Medicine, 2nd ed., 1968, 419Cancer of the Gastro-intestinal Tract (10th Annual Clinical

Conference on Cancer, 1965, University of Texas), 1967, 790Carcinogenesis: A Broad Critique (20th Annual Symposium on

Fundamental Cancer Research, 1966: University of Texas,M. D. Anderson Hospital), 1967, 534

Coppleson, M., and Reid, B.: Preclinical Carcinoma of the CervixUteri, 1967, 677

Cotchin, E., and Roe, F. J. C., eds.: Pathology oJ'Laboratory Ratsand Mice, 1967. 680; erratum, 790

Crawford, T., ed.: Modern Trends in Pathology, Vol. 2, 1967, 415Cruickshank, B., Dodds, T. C., and Gardner, D. L.: Human

Histology, 2nd ed., 1968, 678Dacie, J. V.: The Haemolytic Anaemias, Part III, Secondary or

Symptomatic Haemolytic Anaemias 2nd ed., 1967, 229Dameshek, W., and Dutcher, R. M., eds.: Perspectives in Leukemia,

1968, 788David, H.: Elektronen-Mikroskopische Organ-Pathologie, 1967, 417Denson, K. W. E.: The Use of Antibodies in the Study of Blood

Coagulation, 1967, 677Drury, R. A. B., and Wallington, E. A., eds.: Carleton's Histological

Technique, 4th ed., 1967, 116Dunsford, I., and Bowley, C. C.: Techniques in Blood Grouping,

2nd ed., Parts I and 2, 1967, 419Dybkaer, R., and Jorgensen, K.: Quantities and Units in Clinical

Chemistry, 1967, 679Eichenberger, E., Foa, P. P., and Grillo, T. A. I.: Handbook of

Experimental Pharmacology, Vol. 16, Section 15, 1966, 118Gillies, R. R., and Dodds, T. C.: Bacteriology Illustrated, 2nd ed.,

1968, 789Goldman, L.: Biomedical Aspects of the Laser, 1967, 418Gray, C. H., and Bacharach, A. L., eds.: Hormones in Blood,

2nd ed., Vol. 2, 1967, 788Harper, T. A.: The Peripheral Blood Film, 1968, 788Hart, R. J. C.: A Pocket Virology, 1968, 789Haslewood, G. A. D.: Bile Salts, 1967, 117Hughes, H. E., and Dodds, T. C.: Handbook of Diagnostic Cytology,

1968, 787Irvine, W. J., ed.: Thyrotoxicosis, 1967, 229Jawetz, E., Melnick, J. L., and Adelberg, E. A.: Review of Medical

Microbiology, 7th ed., 230Johnson, S. A., and Seegers, W. H., eds.: Physiology of Hemostasis

and Thrombosis, 1967, 228McAllister, R. A.: Theory of Chemical Pathology Technique, 1967,

535Mayersbach, H. von, ed.: Immunohistochemie (Acta Histochemica,

suppl. 7), 1967, 535Mollison, P. L.: Blood Transfusion in Clinical Medicine, 4th ed.,

1967, 677Myocardial Infarction: Proc. 9th Conference of the International

Society of Geographical Pathology, Leyden, 1966 (Pathologiaet Mvlicrobiologia, Vol. 30, No. 5), 1967, 534

Nerenberg, S. T.: Electrophoresis: A Practical Laboratory Manual,1966, 418

Page, I. H., and McGubbin, J.: Renal Hypertension, 1968, 789Progress in Allergy, Vol. XI, 1967, 679Sandor, G.: Serum Proteins in Health and Disease, 1966, 117Sandritter, W., and Wartman, W. B.: Tissue and Cellar Pathology:

Colour Atlas and Textbook, 2nd ed., 1967, 416Seegers, W. H.: Prothrombin in Enzymology: Thromnbosis and

Hemophilia, 1967, 533Shivas, A. A., ed.: Racial and Geographical Factors in Tumour

Incidence, 1967, 116Simpson, K., ed.: Modern Trends in Forensic Medicine, 2nd Series,

1967, 118Skerman, V. B. D.: A Guide to the Identification of the Genera oj'

Bacteria, 2nd ed., 1967, 229Steere, N. V., ed.: Handbook of'Laboratory Safety, 1967, 680Stott, F. D.: Instruments in Clinical Medicine, 1967, 418Strong, S. J., and Corney, G.: The Placenta in Twin Pregnancy,

1967, 678Sunderman, F. W., and Sunderman, F. W., Jr., eds.: The Clinical

Pathology of Infancy, 1967, 416Swain, R. H. A., and Dodds, T. C.: Clinical Virology, 1967, 228Timbury, M. C.: Notes on Medical Virology, 1967, 229Waterson, A. P.: Introduction to Animal Virology, 1968, 789Weir, D. M., ed.: Handbook of Experimnental Inmnmunology, 1967,

534Wolstenholme, G. E. W., and Porter, R., eds.: The Human Adrenal

Cortex: Its Function Throughout Life (Ciba Foundation StudyGroup, No. 27), 1967, 417

Books received, 419, 681BOTHWELL, T. H. See TORRANCE, J. D., CHARLTON, R. W., SCHMAMAN,

A., LYNCH, S. R., and BOTHWELL, T. H.BOWER, D., and CHADWIN, C. G.: Demonstration of Paneth cell granules

using Naphthalene Black, 107BOYD, J. F., and REID, D.: Bone marrow in nine cases of clinical

glandular fever and a review of the literature, 683

BOYLE, 1. T. See THOMSON, J. A., BOYLE, I. T., MCGIRR, E. M., MACDONALD,E. M., NICOL, j., and BROWN, J.

BRAIN, M. C. See BAKER, L. R. I., BRAIN, M. C., AZZOPARDI, J. G., andWORLLEDGE, S. M.

Brain, trace metals in, 1BRANCIARI, C. See CARAMIA, F., GHERGO, F. G., BRANCIARI, C., and

MENGHINI, G.BREMNER, 1. See cox, J. S. G., MOSS, G. F., BREMNER, 1., and REASON, J.BRIGHT, C. M. J. See GIBBS, D. F., and BRIGHT, C. M. J.BRONKS, 1. G., and BLACKBURN, E. K.: A socio-medical study of

haemophilia and related states (P), 540BROWN, G. W. See COOPER, R. G., and BROWN, G. W.BROWN, J. See THOMSON, J. A., BOYLE, I. T., MCGIRR, E. M., MACDONALD,

E. M., NICOL, j., and BROWN, J.BROWN, R. A. G.: Hepatic and renal damage with paracetamol over-

dosage (P), 793BROZOVICH, B.: Method for the determination of unsaturated iron-

binding capacity of serum using radioactive iron and magnesiumcarbonate, 183

Brucellin skin test, appreciation of (P), 792BRUNSTROM, G. M. See FIELDING, J., KARABUS, C., and BRUNSTROM,

G. M.BUCK, A. C., and COHEN, S. L.: Absorption of antibiotics during

peritoneal dialysis in patients with renal failure, 88BURNS, J. See PENNOCK, C. A., BURNS, j., and MASSARELLA, G. R.BURR, R. G. See BIRD, R., and BURR, R. G.

Calcium in chronic renal failure, 545tubular reabsorption of, in normal and hypercalciuric subjects,353

Cancer, Detection of, 1st International Symposium, 681Candida albicans and 13-haemolytic streptococci, presence and

persistence in vagina of, influence of oral contraceptives on (P),791

-species, tetrazolium medium in diagnosis of, 383CARAMIA, F., GHERGO, F. G., BRANCIARI, C., and MENGHINI, G.: New

aspect of hepatic nuclear glycogenosis in diabetes, 19Carbohydrate Metabolism, Disorders of, Conference on, 681Carcinoid tumours, argentaffin and non-argentaffin, of appendix, 60Carcinoma, cervical, phosphohexose isomerase as screen test for, 24

of lung in diffuse interstitial pulmonary fibrosis, 486plasma zinc and copper measurements in, 363thyroid, and Cushing's syndrome, 129

CARTEI, G. C. See BARRY, M., and CARTEI, G. C.CARTER, A., CROSLAND-TAYLOR, P. j., and STEWART, J. W.: Measurement

of mean corpuscular and packed cell volumes with a Coultercell counter, 222

CASTELAN, D. J., HIRSH, 1., and MARTIN, M.: Latex-bound antifibrinogentest for plasma fibrinogen assay, 638

Catecholamines, plasma, semi-automated differential determinationof, 759

Cathode-ray tube displays in data processing, 281Cells, defect in vitamin B,2 deficiency, investigation of (P), 792Central nervous system, white matter of, spongy degeneration in,

associated with hyperglycinuria, 456Cephaloridine and cephalothin, resistance of penicillinase-forming

strains of Staph. aureus and penicillinase-negative variants to, 75Cerebrospinal fluid protein, estimation of, 518Cervical carcinoma, phosphohexose isomerase as screen test for, 24Cervix uteri, epithelial abnormalities of, histological diagnosis of, 67CHADWIN, C. G. See BOWER, D., and CHADWIN, C. G.CHAKRABARTI, R., BIELAWIEC, M., EVANS, J. F., and FEARNLEY, G. R.:

Methodological study and a recommended technique for deter-mining the euglobulin lysis time, 698

CHALMERS, D. G.: A custom-built hospital blood bank, 673Investigation of the cellular defect in vitamin B12 deficiency (P),792

Chancres, suspected, fluorescent technique for demonstration oftreponemes in films from, 108

CHARLTON, R. W. See TORRANCE, J. D., CHARLTON, R. W., SCHMAMAN.A., LYNCH, S. R., and BOTHWELL, T. H.

Chemical pathology, coding systems for data processing, 254Chinese, glucose-6-phosphate dehydrogenase deficiency in, 44CHISHOLM, D. M., and MASON, D. K.: Labial salivary gland biopsy in

Sjogren's disease, 656Chloride content of skeletal muscle in health and disease, 555Cholesterol in chronic renal failure, 551CHOU, G. See HUANG, C. T., and CHOU, G.CHRISTIAN, M. See ROBINSON, G. L., and CHRISTIAN, M.Christmas disease due to abnormal factor IX, 160Chromatography, gas, in multipurpose assay for urinary cortico-

steroids, 372CHURCHER, G. M.: A screening test for the detection of methicillin-

resistant staphylococci, 213Cirrhosis of liver, spur cell anaemia in, role of lipoproteins information

of, 620CLARK, A. E. See TIGHE, J. R., CLARK, A. E., EISINGER, A. j., and JoNEs,

N. F.See TIGHE, J. R., CLARK, A. E., and TURVEY, D. J.

CLAYTON, Y. M., and MIDGLEY, G.: A new approach to the investigationof scalp ringworm in London schoolchildren (P), 791

Index

Clinical Pathology, 7th International Congress, 681COCKER, J., FOX, H., and LANGLEY, F. A.: Consistency in the histological

diagnosis of epithelial abnormalities of the ctrvix uteri, 67CODD, A. A.: A simple device for microdialysis, 113

See also INGHAM, H. R., SELKON, J. B., CODD, A. A., and HALE,J. H.

COHEN, S. L. See BUCK, A. C., and COHEN, S. L.Coliform and Proteus meningoencephalitis in neonates, 422Colitis, ulcerative, intestinal antibodies in (P), 536COLLEN, D., TYTGAT, G., and VERSTRAETE, M.: Semi-automatic method

for routine evaluation of fibrinolytic components, 705COLLIER, H. B.: Some problems in the use of the Coulter counter for

erythrocyte total counts and volume distribution, 179Colorimetric method for estimation of methylmalonic acid in urine,

221- methods for determination of uric acid levels in uraemia, 192- ultramicro method for estimation of N.E.F.A. in serum, 567Communication systems in data processing, 238Complement-fixation test, Reiter protein, in serodiagnosis of syphilis

in pregnancy, 731- tests, automation of, evaluation of Technicon AutoAnalyzer for,

521Computer in cytology (P), 538- input systems in data processing, 263- programming for laboratory data processing, 289Conference on Disorders of Carbohydrate Metabolism, 681Congress of Clinical Pathology, 7th International, 681CONSTANTOULAKIS, M. See THEODOROPOULOS, G., MAKKOUS, A., and

CONSTANTOULAKIS, M.Contraceptives, oral, influence on presence and persistence of C.

aloicans and 3-haemolytic streptococci in vagina (P), 791-, patients taking, and pregnant women, assessment of thyroidstatus by free thyroxine index in, 767

COOK, I. A. See MURRAY, W. D., and COOK, I. A.COOKE, K. B. See MACKENZIE, D. H., WILSON, J. F., and COOKE, K. B.COOPER, R. G., and BROWN, G. W.: Pletiomonas shigelloides in South

Australia, 715-, KAHN, R. A., CORNELL, C. N., and MUHRER, M. E.: Erythrocyte

mechanical fragility test, 781Copper, neutron activation analysis for, in Wilson's disease, 8-, plasma, measurements of, in malignant disease, 363CORNELL, C. N. See COOPER, R. G., KAHN, R. A., CORNELL, C. N., and

MUHRER, M. E.Corrections, 114, 212, 790CORSE, J., and WILLIAMS, R. E. o.: Antibiotic resistance of coagulase-

negative staphylococci and micrococci, 722Corticosteroids, urinary, multipurpose gas chromatographic assay

for, 372Coulter counter, measurement of mean corpuscular and packed cell

volumes with, 222- -, problems in use for erythrocyte total counts and volume

distribution, 179COWAN, J. D. See ANDERSON, B. B., and COWAN, J. D.COX, J. S. G., MOSS, G. F., BREMNER, 1., and REASON, J.: Intravenous

iron-dextran: studies on unsaturated iron-binding capacity, 611CRAIG, A. W. See GARRETT, J. V., CRAIG, A. W., and JACKSON, S. M.CRAIG, I. See MORE, J. R. S., DAWSON, D. W., RALSTON, A. J, and CRAIG, 1.CRAMP, D. G.: Automated enzymatic fluorometric method for the

determination of pyruvic and lactic acids in blood, 171Creatine, estimation in red cells, 412CRIPPS, C. M.: Rapid method for the estimation of plasma haemo-

globin levels, 110CROOK, J. C.: Morphogenesis of testicular tumours, 71CROSLAND-TAYLOR, P. J. See CARTER, A., CROSLAND-TAYLOR, P. J., and

STEWART, J. W.CROSS, R. M.: A clinicopathological study of nodular sclerosing

Hodgkin's disease, 303CRUICKSHANK A. H.: Non-parasitic cysts of the liver (P), 538Cryoprecipitation, plasma fractions prepared by, factor VIII and

antibody levels in, 635Cryoproteins, plasma, clotting factor V activity in, 702CULE, J., and EVANS, I. L.: Porotic hyperostosis and the Gelligaer

skull, 753Culture plates, quick-drying sterile cabinet for, 670CUMINS, J. N.: Trace metals in the brain and in Wilson's disease, 1CUMMING, J. D., and PERCIVAL, H. G.: Effects of two oral iron prepara-

tions on results of the benzidine test for occult blood in stools, 41Cushing's syndrome and thyroid carcinoma, 129Cyanocobalamin. See Vitamin B,,Cystinosis, lysosomal storage of cystine in lymph node in, electron

microscopic evidence of, 571Cysts, dermoid, of ovary associated with autoimmune haemolytic

anaemia, 626- of liver, non-parasitic (P), 538Cytochrome oxidase activity in gastric mucosa in iron deficiency, 616Cytology, computer in (P), 538Cytomegalic inclusion disease in adult, 311

DARRELL, J. H., GARROD, L. P., and WATERWORTH, P. M.: Trimethoprim:laboratory and clinical studies, 202

Data processing, coding systems in, 251

797

for chemical pathology data, 254-- for haematological data, 252-- for microbiological data, 256-, for microorganisms, 258-- for serological tests, 261-- for viruses, 260

-- communication systems for, 238--,computer programming for, 289--, context and scope, 231

-- definition of, 231-- descriptive analysis of procedures, 238

-- facsimile telegraphy with electrowriter for, 245--,- -M Murfax equipment for, 244-- flowchart method of analysis, 235

- - charts, forms of, 237--in clinical pathology, Report of A.C.P. Working Party on,231-301

-- input systems, 262-- laboratory findings in, presentation of, 281- -, - report forms in, cumulative type, 287

---, pay slip type, 287---, request/report type, 284

--line----, simple type, 283- line transmission of digital information for, 245-- magnetic tape and magnetic character reading for, 269--, optical character and optical mark reading for, 269

-- output systems, 278using electric typewriters, 279- graphic display devices, 280

--,-- e- line-printers, 279-- patient identification for, 247- ---, mechanical reproduction of records, 249

--, pneumatic tube transport systems in, 243--, problems and aims in, 297--, punched card systems for, 263-,- paper tape systems for, 267--,recommendations of A.C.P. Workirng Party, 298-- specimen identification for, 250

-- storage and retrieval for, 269---, using cumulative record card, 273- -,-duplduplicate request/report form, 273

--,- ---,-magnetic file, 277--,----,-punched cards, 275--systems analysis, 235---, basic forms of, 235-- -' choice of scheme, 237-- -' future objectives of, 232--- need for review of, 231

work load assessment for, 232DAVEY, M. G., and LANDER, H.: Effect of injected heparin on platelet

levels in man, 55DAVIDSOHN, I. See LEE, C. L., ZANDREW, F., and DAVIDSOHN, 1.DAVIDSON, R. J. L. See HALL, M., and DAVIDSON, R. J. L.-. See RIDDELL, E. M., and DAVIDSON, R. J. L.DAVIES, I. J. T., MUSA, M., and DORMANDY, T. L.: Measurements of

plasma zinc, 359DAVIES, R. R.: Mycological tests and onychomycosis, 729DAWSON, D. W. See MORE, J. R. S., DAWSON, D. W., RALSTON, A. J., and

CRAIG, 1.DAY, M. See MUIR, G. G., and DAY, M.DENNY, M. J., and PARTRIDGE, B. M.: Tetrazolium medium as an aid

in the routine diagnosis of Candida, 383DENSON, K. W. E., BIGGS, R., and MANNUCCI, P. M.: An investigation of

three patients with Christmas disease due to an abnormal typeof factor IX, 160

Deoxyribonuclease in screening test for Serratia, 210Dermoid cysts of ovary associated with autoimmune haemolytic

anaemia, 626DEVI, B., JENNISON, R. F., and LANGLEY, F. A.: Significance of placental

pathology in transplacental haemorrhage, 322Diabetes, hepatic nuclear glycogenosis in, 19Diabetic glomerulosclerosis and hyalinization of islets of Langerhans,

correlation between (P), 536Diacetyl monoxime-thiosemicarbazide procedure for determination of

urea, 527Dialysis, peritoneal, in chronic renal failure, absorption of antibiotics

during, 88Diarrhoea, infant, due to E. coli 091 K? H7, 387Dimethylsulphoxide starch solution for amylase determination, 764Dip-inoculum transport medium spoon method, detection of

bacteriuria in women at antenatal clinics by, 445DISCHE, F. E.: Argentaffin and non-argentaffin carcinoid tumours of the

appendix, 60DISCOMBE, G.: Preparation of 2-(4'-hydroxybenzeneazo)-benzoic acid

(HABA) (L), 787DONALDSON, D., and LASCELLES, P. T.: An assessment of serum 5"Co

cyanocobalamin as an index of vitamin B12 absorption (P), 792DORMANDY, L.T. See DAVIES, 5. J. T., MUSA, M., and DORMANDY, T. L.DOUGLAS, A. S. Se WILSON, P. A., MCNICOL, G. P., and DOUGLAS, A. S.DOWNER, S. J., and OLIVER, R. A. M. : Radioisotopic assay of vitamin

B,2 (L), 226DRASAR, B. S. See TROTMAN, R. E., and DRASAR, B. S.Drug addiction, laboratory investigation of (P), 539

798 Index

Drugs, sensitivity of Proteus species to, 103Drying cabinet, sterile, for culture plates, 670DYKE, S. C.: Percy Lazarus-Barlow (Obituary), 227DYMOCK, 1. W., and GRAY, B.: Staining method for the examination of

the small intestinal villous pattern in necropsy material, 748

EASTHAM, R. D.: Improved control of long term anticoagulant therapyusing the partial thromboplastin clotting time (P), 539

Editorials: 21st birthday, 421EDMUNDS, P. N.: Quick-drying sterile cabinet for culture plates, 670Education, postgraduate, for pathologists, 115EISINGER, A. J. See TIGHE, J. R., CLARK, A. E., EISINGER, A. J., and

JONES, N. F.Elastofibroma dorsi, 463, 470Electron microscopy in diagnosis of herpes simplex encephalitis (P),

537- of renal biopsy (P), 793

Electrowriter system for facsimile telegraphy in data processing, 245ELPHICK, M. C.: Modified colorimetric ultramicro method for estimating

Nefa in serum, 567ELSTON, H. R., and ELSTON, J. H.: Further use of deoxyribonuclease in

a screening test for Serratia, 210ELSTON, J. H. See ELSTON, H. R., and ELSTON, J. H.Engel, Stefan (Obituary), 420Enzymatic fluorometric method, automated, for determination of

pyruvic and lactic acids in blood, 171-methods for determination of uric acid levels in uraemia, 192Enzymes in chronic renal failure, 551Eosinophilia, pulmonary tropical, filarial complement-fixation test

with Ascaris antigen for, 394Epithelial abnormalities of cervix uteri, histological diagnosis of, 67Erythraemic myelosis, acute, combined with pernicious anaemia, 590Erythrocytes, creatine in, estimation of, 412-, foetal and maternal, differentiation in formol-fixed tissues, 783- mechanical fragility test, 781- microangiopathic, physiological significance of (P), 793-, role in acute platelet response to operation, 695

total counts and volume distribution, problems in use of Coultercounter for, 179

Erythropoietic porphyrin hepatitis, 157Escherichia coli 091 K? H7, infant diarrhoea due to, 387Euglobulin lysis time, methodological study and determination of,

698EVANS, D. j., and WILLIAMS, E. D.: Cytomegalic inclusion disease in

the adult, 311EVANS, I. L. See CULE, j., and EVANS, 1. L.

EVANS, J. F. See CHAKRABARTI, R., BIELAWIEC, M., EVANS, J. F., and

FEARNLEY, G. R.EVANS, R. T.: Manual and automated methods for measuring urea

based on a modification of its reaction with diacetyl monoximeand thiosemicarbazide, 527

Facsimile telegraphy with electrowriter for data processing, 245--- Mufax equipment for data processing, 244Factor V activity in plasma cryoproteins, 702

VIII and antibody levels in plasma fractions prepared by cryo-precipitation, 635

-IX, abnormal, Christmas disease due to, 160-XIII, inhibition by heparin (P), 793Faeces, occult blood in, benzidine test for, effect of oral iron prepara-

tions, 41-,---, ortho-dianisidine paper test for (L), 675

Farmer's lung, precipitin test using immunoosmophoresis for diagnosisof, 376

Fatty acids, binding of neomycin and analogues in vitro by, 564- -, non-esterified, in serum, estimation by colorimetric ultramicro

method, 567FEARNLEY, G. R. See CHAKRABARTI, R., BIELAWIEC, M., EVANS, J. F.

and FEARNLEY, G. R.

FELL, G. S., SMITH, H., and HOWIE, R. A.: Neutron activation analysisfor copper in biological material applied to Wilson's disease, 8

FELTEN, A. VON, STRAUB, P. W., and FRICK, P. G.: Clotting factor Vactivity in plasma cryoproteins, 702

FENTON, J. C. B., and WILLIAMS, A. H.: Improved methods for the esti-mation of plasma ammonia by ion exchange, 14See also FRASER, G. P., and FENTON, J. C. B.

Ferrioxamine, estimation in jaundiced urine, 169Fibrin degradation products and fibrinolysis in renal disease, 140Fibrinogen degradation products, effect on platelet aggregation, 147-, plasma, assay of, latex-bound antifibrinogen test for, 638Fibrinolysis and fibrin degradation products in renal disease, 140- in leukaemia, 136Fibrinolytic activity, determination by dilute blood clot lysis time,

micro modification of, 780- components, semi-automatic evaluation of, 705Fibrosis, pulmonary, diffuse interstitial, carcinoma of lung in, 486FIELDING, J., KARABUS, C., and BRUNSTROM, G. M.: Storage iron

depletion in male blood donors: its significance for iron status inwomen, 402

-, and RYALL, R.: Polysterene tubes in clinical chemistry with specialreference to iron (L), 415

Filarial complement-fixation test for pulmonary tropical eosinophiliawith Ascaris antigen, 394

FINLAYSON, N. D. C., SHEARMAN, D. J. C., SIMPSON, J. D., and GIRDWOOD,R. H.: Determination of vitamin B11 absorption by a simplewhole body counter, 595

FLANAGAN, P. See MARENGO-ROWE, A. J., MCCRACKEN, A. W., andFLANAGAN, P.

FLEAR, C. T. G., FLORENCE, I., and WILLIAMS, J. A.: Water, sodium,potassium, and chloride content of skeletal muscle in fit and illsubjects, 555

FLORENCE, I. See FLEAR, C. T. G., FLORENCE, i., and WILLIAMS, J. A.Fluorescent antibody test, indirect, detection of circulating antibody

in human Toxocara infections by, 449-technique for demonstration of treponemes in films from suspected

chancres, 108Fluoride, inorganic, determination in biological material by potentio-

metric method, 668Fluorometric method, enzymatic, automated, for determination of

pyruvic and lactic acids in blood, 171Foetus, liver cells, recovery after storage in liquid nitrogen, 109Folic acid prophylaxis in women with pernicious anaemia pregnant

after periods of infertility, 599Formaldehyde and low-temperature steam sterilization, residual

formaldehyde after, 771FOX, B., and RISDON, R. A.: Carcinoma of the lung and diffuse inter-

stitial pulmonary fibrosis, 486FOX, H. See COCKER, J., FOX, H., and LANGLEY, F. A.-. See GILLIE, I., and FOX, H.FRANCE, D. R., and MARKHAM, N. P.: Epidemiological aspects of

Proteus infections with particular reference to phage typing, 97FRASER, G. P., and FENTON, J. C. B.: A stable starch preparation for

amylase determinations, 764FRICK, P. G. See FELTEN, A. VON, STRAUB, P. w., and FRICK, P. G.FRY, D. See MARKS, V., and FRY, D.

GARNER, M. F., and ROBSON, J. H.: A fluorescent technique for demon-strating treponemes in films made from suspected chancres, 108-: An immunofluorescence method for the diagnosis of primarysyphilis using an absorption technique, 576

GARRETT, J. V., CRAIG, A. w., and JACKSON, S. M.: A method of measur-ing the lymphocyte transformation response after phytohaemag-glutinin stimulation employing a gamma-emitting isotope andits use in investigating patients with Hodgkin's disease (P), 540

GARROD, L. P. See DARRELL, J. H., GARROD, L. P., and WATERWORTH,P. M.

Gas chromatography in multipurpose assay for urinary cortico-steroids, 372

Gastric mucosa, cytochrome oxidase activity in iron deficiency, 616Gel filtration on Sephadex G-200 in analysis of blood group anti-

bodies, 708Gelligaer skull, porotic hyperostosis in, 753GHERGO, F. G. See CARAMIA, F., GHERGO, F. G., BRANCIARI, C., and

MENGHINI, G.Giant cell myocarditis limited to left atrium, with mitral stenosis, 750GIBBS, D. F.: Effect of blood on the assay of 6-phosphogluconate

dehydrogenase in vaginal fluid, 189and BRIGHT, C. M. J.: Improved automated methods of proteindetermination, 777

GIBSON, G. L., JOHNSTON, H. P., and TURKINGTON, V. E.: Residualformaldehyde after low-temperature steam and formaldehydesterilization, 771

GILLESPIE, W. A. See LINTON, K. B., and GILLESPIE, W. A.GILLIE, i., and FOX, H.: Mitral stenosis together with a giant cell

myocarditis limited to the left atrium, 750GIMLETTE, T. M. D., and PIFFANELLI, A.: Assessment of thyroid status

in pregnant women and in patients taking oral contraceptivesby a free thyroxine index, 767

GIRDWOOD, R. H. See FINLAYSON, N. D. C., SHEARMAN, D. J. C.,SIMPSON, J. D., and GIRDWOOD, R. H.

Glandular fever, bone marrow findings in, nine cases and review ofliterature, 683extreme neuropenia in, 48seronegative, 50

Glomerulosclerosis, diabetic, and hyalinization of islets of Langerhans,correlation between (P), 536

Glucagon test for insulinoma, chemical study of, in 25 cases, 346Glucose in chronic renal failure, 548Glucose-6-phosphate dehydrogenase deficiency in Chinese, 44Glycogenosis, hepatic nuclear, in diabetes, 19Glycosaminoglycans and glycoproteins, excretion patterns in normal

urine, 339GOLD, G.: The quantitation of asbestos in tissue (P), 537GOODWIN, C. S., and STEWART, A. E.: Detection of bacteriuria in

women attending local authority antenatal clinics using thedip-inoculum transport medium spoon method, 445

Granuloma pyogenicum and Kaposi's sarcoma in Uganda, com-parative study of, 119

Graph plotters in data processing, 280GRAY, B. See DYMOCK, I. W., and GRAY, B.

Index

GREAVES, J. L. See HUGHES, M. H., GREAVES, J. L., and BETTELHEIM,K. A.

GREEN, A.: Colorimetric method for estimating methylmalonic acidin urine, 221

GREEN, A. E., and SIGNY, A. G.: Determination of haematocrit usingthe SMA-4 (L), 533

GREEN, J.: Inhibition of factor XIII by heparin (P), 793GREENBERG, S. R. See MILLISER, R. V., GREENBERG, S. R., and NEIMAN,

B. H.GRIFFITHS, w. a.: Estimation of creatine in red cells, 412

Haematocrit, determination with AutoAnalyzer SMA-4 (L), 114, 533Haematology, coding systems for data processing, 252Haemochromatosis, and histochemical and chemical iron in liver of

control subjects, 35Haemoglobin D Los Angeles-beta thalassaemia, suppression of

haemoglobin A synthesis in, 508- Hammersmith, congenital Heinz body haemolytic anaemia due to

(P), 540- in chronic renal failure, 550-, plasma levels, estimation of, 110Haemolytic anaemia, autoimmune, associated with ovarian dermoid

cyst, 626--, Heinz body, congenital, due to haemoglobin Hammersmith

(P), 540--, microangiopathic (P), 793Haemophilia and related states, sociomedical study of (P), 540Haemorrhage, transplacental, significance of placental pathology in,

322Haemostatic mechanism in uraemia, 406HALE, J. H. See INGHAM, H. R., SELKON, J. B., CODD, A. A., and HALE,

J. H.HALL, M., and DAVIDSON, R. J. L.: Prophylactic folic acid in women with

pernicious anaemia pregnant after periods of infertility, 599Halo naevi, 118 cases of (P), 537HAWIGER, J.: Frequency of staphylococcal lysozyme production

tested by plate method, 390HAWKEY, C. M. See SPITTLE, C. R., LANSDOWN, N. M., and HAWKEY,

C. M.HAWKSWORTH, J. See MANLEY, G., SEVERN, M., and HAWKSWORTH, J.Heart, pathology of, in tenth decade, 317HEIMER, G. V. See TAYLOR, C. E. D., KERSHAW, J. w., and HEIMER, G. V.Heinz body haemolytic anaemia, congenital, due to haemoglobin

Hammersmith (P), 540Heparin, inhibition of factor XIII by (P), 793- injections, effect on platelet levels, 55Hepatic nuclear glycogenosis in diabetes, 19Hepatitis, erythropoietic porphyrin, 157-, infectious, lack of production of interfering substances in (P), 794Herpes simplex encephalitis, electron microscopy in diagnosis of (P),

537HEWITT, J. H., and PARKER, M. T.: Sensitivity of penicillinase-forming

strains of Staphyloccus aureus and of their penicillinase-negativevariants to cephaloridine, cephalothin, methicillin, and benzyl-penicillin, 75

HINGERTY, D. See RYAN, M. P., and HINGERTY, D.HIRSH, J. See CASTELAN, D. J., HIRSH, J., and MARTIN, M.HIRST, A. D.: Ultramicro automation of serum total proteins and

protein fractions (P), 538HOCKLEY, A. B. See ZUCKERMAN, A. J., KAY, H. E. M., and HOCKLEY,

A. B.Hodgkin's disease, lymphocyte transformation response after

phytohaemagglutinin stimulation in, measurement by 1ii5-labelled IUdR (P), 540

--, nodular sclerosing, clinicopathological study of, 303--, 600 cases of lymphadenopathy with initial biopsy diagnosis of,

eventual diagnosis after review, 650HODSON, J. J., and PROUT, R. E. S.: Chemical and histochemical

characterization of mucopolysaccharides in a jaw myxoma, 582Hormones in chronic renal failure, 548HORN, R. C. See WILLIAMS, E. D., MORALES, A. M., and HORN, R. C.Horse agglutinins for differential diagnosis of infectious mono-

nucleosis, 631HOUSLEY, J.: Alpha,-macroglobulin levels in disease in man, 27HOWELLS, C. H. L.: An appreciation of the brucellin skin test (P), 792HOWIE, R. A. See FELL, G. S., SMITH, H., and HOWIE, R. A.HOWORTH, P. J. N., and ZILVA, J. F.: Determination of uric acid levels

in uraemia by enzymatic and colorimetric techniques, 192HUANG, C. T., and CHOU, G.: Drug sensitivity of Proteus species, 103HUGHES, M. H., GREAVES, J. L., and BETTELHEIM, K. A.: Infant diarrhoea

due to Escherichia coli 091 K? H7, 387HURWORTH, E. See BARNES, H. D., HURWORTH, E., and MILLAR, J. H. D.HUTCHISON, H. E. See WARDROP, C., and HUTCHISON, H. E.HUTTON, R. A., and O'SHEA, M. J.: Haemostatic mechanism in uraemia,

406Hyalinization of islets of Langerhans and diabetic glomerulosclerosis,

correlation between (P), 5362-(4'-Hydroxybenzeneazo)-benzoic acid, preparation of (L), 787Hypercalciuria, tubular reabsorption of calcium in, 353Hyperglycinuria, spongy degeneration of white matter of central

nervous system associated with, 456

799

Hyperostosis, porotic, in Gelligaer skull, 753Hypogammaglobulinaemia, primary 'acquired', and amyloidosis, 32

Immunofluorescence method for diagnosis of primary syphilis usingabsorption technique, 576

Immunoosmophoresis, precipitin test using, for diagnosis of farmer'slung, 376

Infertility in women with pernicious anaemia, folic acid prophylaxisduring pregnancy after, 599

INGHAM, H. R., SELKON, J. B., CODD, A. A., and HALE, J. H.: A studyin vitro of the sensitivity to antibiotics of Bacteroidesjragilis, 432

Inoculating loop, electrically-heated, 224Insulinoma, glucagon test for, chemical study of, in 25 cases, 346Interferon and interfering substances, lack of production of, in

infectious hepatitis (P), 794Intestinal antibodies in ulcerative colitis (P), 536Intestine, small, villous pattern in necropsy material from, staining

method for examination of, 748Iodine, protein-bound, estimations of, screening test for, 530Iodo-deoxyuridine, 1"i5-labelled, measurement of lymphocyte trans-

formation response after phytohaemagglutinin stimulation by,with use in Hodgkin's disease (P), 540

Iron, chelated, determination in urine, 166- deficiency, cytochrome oxidase activity in gastric mucosa in, 616- dextran, intravenous, effect on unsaturated iron-binding capacity,

611--, single massive infusion of, lymph node enlargement after, 492-estimation, use of polystyrene tubes in (L), 415-, histochemical and chemical, in liver of control subjects, and

diagnosis of iron overload, 35-metabolism in chronic renal failure, 550-preparations, oral, effect on benzidine test for occult blood in

stools, 41-, radioactive, and magnesium carbonate, determination of un-

saturated iron-binding capacity of serum with, 183-, serum, estimation by modified Sanford technique, effect of

unconjugated bilirubin, 776-, -, total iron-binding capacity, and percentage saturation in

normal subjects, 603-, storage, depletion in male blood donors, and iron status in women,

402-,-, in muscle cells and tissue histiocytes in Bantu, 495Islets of Langerhans. See Langerhans, islets of

JACKSON, S. M. See GARRETT, J. V., CRAIG, A. W., and JACKSON, S. M.JACOBS, S. C.: Assessment of automated nitrogen analysis of biological

fluids with reference to the Kjeldahl method, 218JAMESON, J. E.: Rapid and sensitive precipitin test for the diagnosis of

farmer's lung using immunoosmophoresis, 376Jaundice, estimation of ferrioxamine in urine in, 169Jaw myxoma, mucopolysaccharides in, chemical and histochemical

characterization of, 582JEAN, G., LAMBERTENGHI, G., and RANZI, T.: Ultrastructural study of

the liver in hepatic porphyria, 501JENNISON, R. F. See DEVI, B., JENNISON, R. F., and LANGLEY, F. A.JOHNSTON, H. P. See GIBSON, G. L., JOHNSTON, H. P., and TURKINGTON,

V. E.JONES, A. W. See BARSON, A. J., JONES, A. W., and LODGE, K. V.JONES, N. F. See TIGHE, J. R., CLARK, A. E., EISINGER, A. J., and JONES,

N. F.JOSHI, V. V.: Pathology of hereditary nephritis, 744Journal of Clinical Pathology, 21st birthday of, 421- - Medical Microbiology, 118

KAHN, R. A. See COOPER, R. G., KAHN, R. A., CORNELL, C. N., andMUHRER, M. E.

Kaposi's sarcoma and granuloma pyogenicum in Uganda, com-parative study of, 119

KARABUS, C. See FIELDING, J., KARABUS, C., and BRUNSTROM, G. M.KAY, H. E. M. See ZUCKERMAN, A. J., KAY, H. E. M., and HOCKLEY,

A. B.KERSHAW, J. W. See TAYLOR, C. E. D., KERSHAW, J. W., and HEIMER,

G. V.Kidney damage with paracetamol overdosage (P), 793KIPPAX, P. W., SAEED, N., and PAMPLIN, W. A. V.: An unusual Neisseria

isolated from a case of meningitis, 440KIRKLAND, J. A.: The computer and cytology (P), 538Kjeldahl technique, modified, for automated nitrogen analysis of

biological fluids, 218

Labial salivary gland biopsy in Sjogren's disease, 656LACEY, R. W.: Binding of neomycin and analogues by fatty acids in

vitro, 564Lactic acid in blood, automated enzymatic fluorometric method for

determination of, 171Lactobacillus casei assay, effect of light on, 85Lactose, plasma and urinary, specific determination of, 112

800

LAI, H. C., LAI, M. P. Y., and LEUNG, K. S. N.: Glucose-6-phosphatedehydrogenase deficiency in Chinese, 44

LAI, M. P. Y. See LAI, H. C., LAI, M. P. Y., and LEUNG, K. S. N.

LAKE, B. D. See PATRICK, A. D., and LAKE, B. D.LAMBERTENGHI,G. See JEAN,G., LAMBERTENGHI, G., and RANZI, T.LAMONT, A. See LAPPIN, T.J. R., and LAMONT, A.

LANDER, H. See DAVEY,M.G., and LANDER, H.Langerhans, islets of, hyalinization of, and diabetic glomerulo-

sclerosis, correlation between (P), 536LANGLEY, F. A. See COCKER, J., FOX, H., and LANGLEY, F. A.-. See DEVI, B., JENNISON, R. F., and LANGLEY, F. A.LANSDOWN, N.M. See SPITTLE, C. R., LANSDOWN, N. M., and HAWKEY,

C. M.LAPPIN, T.J. R., and LAMONT, A.: A cause of error in the determination

of the haematocrit using the SMA-4 (L), 114LASCELLES, P. T. See DONALDSON, D., and LASCELLES, P. T.Lazarus-Barlow, Percy (Obituary), 227LEE, C. L., ZANDREW, F., and DAVIDSOHN, I.: Horse agglutinins in

infectious mononucleosis. 111. Criterion for differential diagnosis,631

LEE, F. D.: A comparative study of Kaposi's sarcoma and granulomapyogenicum in Uganda, 119

Leucocyte count, sex difference in, 691Leukaemia, fibrinolysis in, 136LEUNG, K. S. N. See LAI, H. C., LAI, M. P. Y., and LEUNG, K. S. N.LEWIN, K.: Neoplastic Paneth cells, 476Librium, determination in urine, 366LIE, J. T.: Evaluation of a nitrite test kit (Stat-test) for the detection

of significant bacteriuria, 443Light, eff-ct on L. casei assay, 85Line transmission of digital information for data processing, 245Line-printers in data processing, 279LINTON, K. B., and GILLESPIE, W. A.: Collection of urine from female

patients for bacteriological examination (P), 539Lipids, content in malignant lymphomas, 643-in chronic renal failure, 551Lipoproteins, role in formation of spur cell anaemia, in cirrhosis of

liver, 620Liver biopsy, adult, tissue culture of (P), 793

-, m-thod for obtaining both frozen and paraffin sections from,413

cells, foetal, recovery after storage in liquid nitrogen, 109,cirrhosis of, spur cell anaemia in, role of lipoproteins in formation

of, 620cysts of, non-parasitic (P), 538damage with paracetamol ovzrdosage (P), 793histochemical and chemical iron in control subjects, and diagnosisof iron overload, 35

in hepatiz porphyria, ultrastructural study of, 501LODGE, K. V. See BARSON, A. J., JONES, A. w., and LODGE, K. V.LUNDIN, P. See '5EINFELD, A., LUNDIN, P., and LUNDVALL, 0.

LUNDVALL, O. See WEINFELD, A., LUNDIN, P., and LUNDVALL, 0.

Lung, carcinoma of, in diffuse interstitial pulmonary fibrosis, 486Lymph node enlargement after single massive infusion of iron dextran,

492- lysosomal storage of cystine in cystinosis in, electron micro-

scopic evidence of, 571Lymphadenopathy, eventual diagnosis in 600 cases reviewed after

initial biopsy diagnosis of Hodgkin's disease, 650226 cases reviewed after initial biopsy diagnosis of

reticulum cell sarcoma, 654primary, complicating idiopathic steatorrhoea (P), 536

Lymphocyte transformation response after phytohaemagglutininstimilation, measurement by I'25-labelled lUdR, with use inHodgkin's diszase (P), 540

technique for, 175Lymphomas, malignant, lipid content of, 643LYNCH, S. R. See TORRANCE, J. D., CHARLTON, R. W., SCHMAMAN, A.

LYNCH, S. R., and BOTHWELL, T. H.Lysosomes, cystine storage in lymph node in cystinosis by, electron

microscopic evidence of, 571Lysozyme production by staphylococci, frequency tested by plate

method, 390

MCANDREW, G. M. See OGSTON, D., MCANDREW, G. M., and OGSTON,C. M.

MCBRIDE, J. A.: Platelet adhesiveness: the effect of centrifugation on

the mzasurement of adhesiveness in platelet-rich plasma, 397MCCRACKEN, A. w. See MARENGO-ROWE, A. J., MCCRACKEN, A. W., and

FLANAGAN, P.MCCULLOUGH, H.: Semi-automated method for the differential deter-

mination of plasma catecholamines, 759MACDONALD, E. M. See THOMSON, J. A., BOYLE, 1. T., MCGIRR, E. M.,

MACDn)NALD, E. M., NICOL, j., and BROWN, J.MCGIRR, E. M. See THOMSON, J. A., BOYLE, I. T., MCGIRR, E. M., MAC-

DONALD, E. M., NICOL, J., and BROWN, J.MCGIVEN, A. R.: Intestinal antibodies in ulcerative colitis (P), 536MCKEE, G. See WELSHMAN, S. G., and MCKEE, G.MACKENZIE, D. H., WILSON, J. F., and COOKE, K. B.: Elastofibroma,

470MCNICOL, G. P. See WILSON, P. A., MCNICOL, G. P., and DOUGLAS, A. S.

Index

Magnesium carbonate and radioactive iron, determination ofunsaturated iron-binding capacity of serum with, 183

in chronic renal failure, 546serum, determination of, comparison of four methods, 220

Magnetic file system for storage and retrieval of laboratory data,277

-tape and magnetic character reading for data processing, 269MAKKOUS, A. See THEODOROPOULOS,G., MAKKOUS, A., and CONSTAN-

TOULAKIS, M.MALDONADO, M. MARTINEZ-. See MARTINEZ-MALDONADO, M.MANLEY, G. SEVERN,M., and HAWKSWORTH,J.: Excretion patterns of

glycosaminoglycans and glycoproteins in normal human urine,339

MANNUCCI, P. M. See DENSON, K. W. E., BIGGS, R., and MANNUCCI,P. M.

MARENGO-ROWE, A. J., MCCRACKEN, A.W., and FLANAGAN, P.: Completesuppression of haemoglobin A synthesis inhaemoglobin D LosAngeles-beta thalassaemia, 508

MARKHAM, N.P. See FRANCE,D. R., and MARKHAM, N. P.MARKS, V., and FRY,D.: Laboratory investigation of drug addiction

(P), 539and SAMOLS, E.: Glucagon test for insulinoma: a chemical studyin 25 cases, 346

Marrow findings in glandular fever, nine cases and review o fliterature, 683

MARTIN,M. See CASTELAN, D. J., HIRSH, j., and MARTIN, M.MARTIN, N.H.: Foreword to Data Processing Report,facing 231MARTINEZ-MALDONADO, M.: Role of lipoproteins in the formation of

spur cell anaemia, 620MASON, D. K. See CHISHOLM, D.M., and MASON, D. K.MASSARELLA,G. R. See PENNOCK, C. A., BURNS, j., and MASSARELLA,G.-. See WHITEHEAD, R., and MASSARELLA,G. R.Megaloblastic anaemia of pregnancy, clinical and laboratory study

(P), 540MENGHINI, G. See CARAMIA, F., GHERGO, F. G., BRANCIARI, C., and

MENGHINI,G.Meningitis, unusual Neisseria isolated from case of, 440Meningoencephalitis, Proteus and coliform, in neonates, 422Metals in brain and in Wilson's disease, IMetaplastic nodules in rectal mucosa, structure and significance, 735Methicillin resistance in Staph. aureus, screening test for detection

of, 213--of penicillinase-forming strains of Staph. auireus and penicillin-ase-negative variants, 75

Methylmalonic acid in urine, estimation by colorimetric method, 221Microbiology, coding systems for data processing, 256Micrococci and staphylococci, coagulase-negative, antibiotic resistance

of, 722Microdialysis, device for, 113Microorganisms, coding system for data processing, 258MIDDLETON, J. E. See SMITH, P. M., MIDDLETON, J. E., and WILLIAMS, R.MIDGLEY, G. See CLAYTON, Y. M., and MIDGLEY, G.MILLAR, J. H. D. See BARNES, H. D., HURWORTH, E., and MILLAR, J. H. D.MILLISER, R. V., GREENBERG, S. R., and NEIMAN, B. H.: Congenital or

berry aneurysm in the optic nerve, 335MITCHELL, R. G.: Classification of Staphylococcus albus strains

isolated from the urinary tract, 93Mitral stenosis with giant cell myocarditis limited to left atrium, 750Mononucleosis, infectious, differential diagnosis with horse

agglutinins, 631MORALES, A. M. See WILLIAMS, E. D., MORALES, A. M., and HORN, R. C.MORE, J. R. S., DAWSON, D. W., RALSTON, A. j., and CRAIG, I.: Plasma-

cytoma of the thyroid, 661MORRIS, C. A.: Advantage of a routine Reiter protein complement-

fixation test in the serodiagnosis of syphilis in pregnancy, 731The influence of oral contraceptives on the presence and persistenceof Candila albicans and 13-haemolytic streptococci in the vagira(P), 791

MORRISON, D. See TAPP, E., and MORRISON, D.MOSS, G. F. See COX, J. S. G., MOSS, G. F., BREMNER, I., and REASON, J.Mucopolysaccharides in jaw myxoma, chemical and histochemical

characterization of, 582Mucosa, gastric, cytochrome oxidase activity in iron deficiency, 616-, rectal, metaplastic nodules in, structure and significance of, 735Mucosubstances, acidic, in secondary amyloidosis, histochemical

investigation of, 578Mufax system of facsimile telegraphy in data processing, 244MUHRER, M. E. See COOPER, R. G., KAHN, R. A., CORNELL, C. N., and

MUHRER, M. E.MUIR, G. G., and DAY, M.: Precision of urine:whole blood and urine:

plasma ratio for alcohol (P), 794and VALTERIS, G. J.: A trial of phosphohexose isomerase as ameans of detecting cervical carcinoma, 24

MURPHY, D., and WEST, H. F.: Routine multipurpose gas chromato-graphic assay for urinary corticosteroids, 372

MURRAY, W. D., and COOK, 1. A.: Primary 'acquired' hypogamma-globulinaemia and amyloidosis, 32

MUSA, M. See DAVIES, 1. J. T., MUSA, M., and DORMANDY, T. L.Muscle cells and tissue histiocytes, storage iron in, among Bantu,

495skeletal, water, sodium, potassium, and chloride content in healthand disease, 555

Mycological tests and onychomycosis, 729

Index

Myelosis, erythraemic, acute, combined with pernicious anaemia, 590Myocarditis, giant cell, limited to left atrium, with mitral stenosis,

750Myxoma of jaw, mucopolysaccharides in, chemical and histochemical

characterization of, 582

Naevus, halo, 118 cases of (P), 537Naphthalene Black, demonstration of Paneth cell granules with, 107N.E.F.A. See Fatty acids, non-esterifiedNEILL, D. w. See SINNIAH, R., and NEILL, D. W.NEIMAN, B. H. See MILLISER, R. V., GREENBERG, S. R., and NEIMAN,

B. H.Neisseria flavescens, septicaemia caused by, 437-, unusual, isolated from case of meningitis, 440Neomycin and analogues, binding by fatty acids in vitro, 564Neonates, Proteus and coliform meningoencephalitis in, 422Neoplasms, epithelial, of urinary bladder, contiguous but dissimilar,

332Neoplastic Paneth cells, 476Nephritis, hereditary, pathology of, 744Nephrotic syndrome, electron microscopy of renal biopsy in (P), 793Nervous system, central. See Central nervous systemNeuropenia, extreme, in glandular fever, 48NEWMAN, C. G. H. See ROWLAND, R., and NEWMAN, C. G. H.NICOL, J. See THOMSON, J. A., BOYLE, 1. T., MCGIRR, E. M., MACDONALD,

E. M., NICOL, J., and BROWN, J.Nitrazepam (Mogadon), determination in serum and urine, 366Nitrite test kit (Stat-test) for detection of significant bacteriuria,

evaluation of, 443Nitrogen analysis, automated, of biological fluids, with modified

Kjeldahl method, 218-, liquid, recovery of foetal liver cells after storage in, 109NORDIN, B. E. C. See PEACOCK, M., and NORDIN, B. E. C.

Obituaries:Engel, Stefan, 420Lazarus-Barlow, Percy, 227

OGSTON, C. M. See OGSTON, D., MCANDREW, G. M., and OGSTON, C. M.OGSTON, D., MCANDREW, G. M., and OGSTON, C. M.: Fibrinolysis in

leukaemia, 136OLIVER, R. A. M. See DOWNER, S. J., and OLIVER, R. A. M.Onychomycosis, mycological diagnosis of, 729Optic nerve, congenital or berry aneurysm in, 335Optical character and optical mark reading for data processing, 269Ortho-dianisidine paper test for occult blood in faeces (L), 675O'SHEA, M. J. See HUTTON, R. A., and O'SHEA, M. J.Ovary, dermoid cyst of, associated with autoimmune haemolytic

anaemia, 626Oxygen therapy, pulmonary complications of (P), 536

PAINE, C. G.: Differentiation of foetal and maternal erythrocytes informol-fixed tissues, 783

PAMPLIN, W. A. v. See KIPPAX, P. W., SAEED, N., and PAMPLIN, W. A. V.Pancreatin-trypsin solution for liquefaction of sputa for bacterio-

logical examination, 531Paneth cell granules, demonstration with Naphthalene Black, 107- cells, neoplastic, 476Papain-cysteine-anti-D mixture, stability after freeze-drying and

storage, 530Paracetamol overdosage, hepatic and renal damage with (P), 793PARKER, M. T. See HEWITT, J. H., and PARKER, M. T.PARTRIDGE, B. M. See DENNY, M. J., and PARTRIDGE, B. M.PASSANT, L. P. See PENNOCK, C. A., PASSANT, L. P., and BOLTON, F. G.Patient identification for data processing, 247

, mechanical reproduction of records, 249PATRICK, A. D., and LAKE, B. D.: Cystinosis: electron microscopic

evidence of lysosomal storage of cystine in lymph node, 571PEACOCK, M., and NORDIN, B. E. C.: Tubular reabsorption of calcium

in normal and hypercalciuric subjects, 353PELHAM, D. C. THURSBY-. See THURSBY-PELHAM, D. C.Penicillinase-forming strains of Staph. aureus and penicillinase-

negative variants, resistance to cephaloridine, cephalothin,methicillin, and benzylpenicillin, 75

PENMAN, H. G.: Extreme neutropenia in glandular fever, 48-: Seronegative glandular fever, 50PENNOCK, C. A., BURNS, J., and MASSARELLA, G. R.: Histochemical in-

vestigation of acid mucosubstances in secondary amyloidosis,578

-, PASSANT, L. P., and BOLTON, F. G.: Estimation of cerebrospinalfluid protein, 518

PENTYCROSS, C. R.: Technique for lymphocyte transformation, 175PERCIVAL, H. G. See CUMMING, J. D., and PERCIVAL, H. G.Peritoneal dialysis in chronic renal failure, absorption of antibiotics

during, 88Pernicious anaemia. See Anaemia, perniciousPhage typing of Proteus infections for epidemiological investigation, 97PHANSOMBOOM, S.: Human aspergillosis (P), 539Phosphate in chronic renal failure, 545

801

6-Phosphogluconate dehydrogenase assay in vaginal fluid, effect ofblood on, 189

Phosphohexose isomerase as screen test for cervical carcinoma, 24Phytohaemagglutinin stimulation, lymphocyte transformation response

after, measurement by 1i25slabelled lUdR, with use in Hodgkin'sdisease (P), 540

PIFFANELLI, A. See GIMLETTE, T. M. D., and PIFFANELLI, A.Placenta, pathology of, significance in transplacental haemorrhage,

322Placental tissue, formol-fixed, differentiation of foetal and maternal

erythrocytes in, 783Plasma alcohol determination, urine:whole blood and urine:plasma

ratios for (P), 794-ammonium, determination of, comparison between microdiffusion

and ion exchange methods for, 12-,--, improved ion exchange method for, 14and urinary lactose, specific deturmination of, 112

-catecholamines, semi-automated differential determination of, 759-cryoproteins, clotting factor V activity in, 702-fibrinogen assay, latex-bound antifibrinogen test for, 638-fractions prepared by cryoprecipitation, factor VIII and antibody

levels in, 635-haemoglobin levels, estimation of, 110-iron-binding capacity, total, serum iron and percentage saturation

in normal subjects, 603---, unsaturated effict of intravenous iron-dextran, 611

platel3t-rich, measurement of platelet adhesiveness in, effect ofcentrifugation, 397

-zinc, measurements of, in health and disease, 359- and copper, measurements of, in malignant disease, 363

Plasmacytoma of thyroid, 661Platelets. See Blood plateltsPlating out of bacteria on solid medium, rotary machine for, 784Plesiolnonas shigelloides in South Australia, 715Pneumatic tube transport systems in data processing, 243POLLOCK, A.: Factor VIII and antibody levels in plasma fractions

prepared by cryoprecipitation, 635Polystyrene tubes, use in iron estimation (L), 415POMERANCE, A.: Pathology of the heart in the tenth decade, 317Porotic hyperostosis in Gelligaer skull, 753Porphyria, hepatic, liver in, ultrastructural study of, 501Porphyrin hepatitis, erythropoictic, 157Postgraduate education for pathologists, 115Potassium content of skeletal muscle in health and disease, 555- in chronic renal failure, 547Potentiometric method for determination of inorganic fluoride in

biological material, 668PRANKERD, T. A. J. See SHETH, N. K., and PRANKERD, T. A. J.Precipitin test for diagnosis of farmer's lung using immunoosmo-

phoresis, 376Pregnancy in women with pernicious anaemia after periods of

infertility, folic acid prophylaxis during, 599-, megaloblastic anaemia of, clinical and laboratory study (P), 540-, syphilis in, serodiagnosis with Reiter protein complement-fixation

test, 731Pregnant women and patients taking oral contraceptives, assessment

of thyroid status by free thyroxine index in, 767Proteins in cerebrospinal fluid, estimation of, 518-, automated determination of. 777-in chronic renal failure, 549-, serum, changes in relation to urinary tract involvement in spina

bifida (P), 538-,-, total, and protein fractions, ultramicro automation of (P), 538Proteus and coliform meningoencephalitis in neonatts, 422- infections, epidemiological aspects and phage typing, 97- species, drug sensitivity of, 103PROUT, R. E. S. See HODSON, J. J., and PROUT, R. E. S.Pulmonary blastoma, 480- complications of oxygen therapy (P), 536- fibrosis, diffuse interstitial, carcinoma of lung in, 486- tropical eosinophilia, filarial complement-fixation test with Ascaris

antigen for, 394Punched cards for input in data processing systems, 263- for storage and retrieval of laboratory data, 275

-paper tape systems for data processing, 267Pyruvic acid in blood, automated enzymat!c fluorometric method for

determination of, 171

Radioisotopic assay of vitamin Bl, (L), 226RAIA, S., and SCHEUER, P. J.: Method for obtaining both frozen and

paraffin sections from the same liver biopsy, 413RALSTON, A. J. See MORE, J. R. S., DAWSON, D. W., RALSTON, A. J., and

CRAIG, I.RANZI, T. See JEAN, G., LAMBERTENGHI, G., and RANZI, T.RAWLINS, G. A.: Use of a pancreatin-trypsin solution for the liquefaction

of sputa for routine bacteriological examination, 531RAWLINSON, V. I. See STRATTON, F., SMITH, D. S., and RAWLINSON, V. I.RAY, P., and ROBB, P.: Megaloblastic anaemia of pregnancy: a clinical

and laboratory study (P), 540REASON, J. See COX, J. S. G., MOSS, G. F. BREMNER, I., and REASON, J.Rectum, mucosa, metaplastic nodules in, structure and significance

of, 735

802 Index

REID, D. See BOYD,J. F., and REID, D.Reiter protein complement-fixation test in serodiagnosis of syphilis

in pregnancy, 731Renal biopsy, electron microscopy of (P), 793-disease, fibrin degradation products and fibrinolysis in, 140- failure, chronic, absorption of antibiotics during peritoneal

dialysis in, 88-,-, biochemical consequences of, 541

tubular reabsorption of calcium in normal and hypercalciuricsubjects, 353

Reports, laboratory, 281forms for, cumulative type, 287

-,-,--, pay-slip type, 287request/report type, 284simple type, 283

Respiratory Diseases, Acute, Symposium on, 682Reticulum cell sarcoma, 226 cases of lymphadenopathy with initial

biopsy diagnosis of, eventual diagnosis after review, 654Rheumatic heart disease and mitral stenosis with giant cell myocarditis

of left atrium, 750RIDDELL, E. M., and DAVIDSON, R. J. L.: Coexistence of pernicious

anaemia and acute erythraemic myelosis, 590Ringworm of scalp, investigation in London schoolchildren (P), 791RISDON, R. A. See FOX,B., and RISDON, R. A.ROBB P. See RAY,P., and ROBB,P.ROBINSON,G. L., and CHRISTIAN, M.: Filarial complement-fixation test

for pulmonary tropical eosinophilia with Ascaris antigen, 394ROBSON, J. H. See GARNER, M. F., and ROBSON, J. H.ROOME, A.P. C. H., and TOZER, R. A.: Effect of dilution on the growth

of bacteria from blood cultures, 719Rotary machine for plating out bacteria on solid medium, 784ROWE, A. J. MARENGO-. See MARENGO-ROWE, A. J.ROWLAND, R., and NEWMAN, C. G. H.: The pulmonary complications

of oxygen therapy (P), 536ROY, S., and WOLMAN, L.: Diagnostic help of electron microscopy in

herpes simplex encephalitis (P), 537RUNCIE, J. See BARNES, F. w., and RUNCIE, J.RUSHTON, D. I.: Spongy degeneration of the white matter of the central

nervous system associated with hyerglycinuria, 456RYALL. R. See FIELDING, J., and RYALL, R.RYAN, M. P., and HINGERTY, D.: Comparison of four methods for

determining serum magnesium, 220

SAEED, N. See KIPPAX, P. W., SAEED, N., and PAMPLIN, W. A. V.Salivary glands, labial biopsy in Sjogren's disease, 656Salmonella outbreaks, investigation of, new medium for (P), 791SAMOLS, E. See MARKS, v., and SAMOLS, E.Sanford technique, modified, for estimation of serum iron, effect of

unconjugated bilirubin, 776Sarcoma, Kaposi's, and granuloma pyogenicum in Uganda, com-

parative study of, 119reticulum cell, 226 cases of lymphadenopathy with initial biopsydiagnosis of, eventual diagnosis after review, 654

Scalp ringworm, investigation in London schoolchildren (P), 791SCHEUER, P. J. See RAIA, S., and SCHEUER, P. J.SCHMAMAN, A. See TORRANCE, J. D., CHARLTON, R. W., SCHMAMAN, A.,

LYNCH, S. R., and BOTHWELL, T. H.Sclerosing Hodgkin's disease, nodular, clinicopathological study of,

303SELKON, J. B. See INGHAM, H. R., SELKON, J. B., CODD, A. A., and HALE,

J. H.Sephadex G-200 gel filtration in analysis of blood group antibodies,

708Septicaemia caused by Neisseria flavescens, 437Serological tests, coding systems for data processing, 261Seronegative glandular fever, 50Serratia, deoxyribonuclease screening test for, 210Serum alpha2-macroglobulin levels in disease, 27-bilirubin determination, automated method for, 196- t7Co cyanocobalamin, assessment as index of vitamin B,, ab-

sorption (P), 792-iron, estimation by modified Sanford technique, effect of uncon-

jugated bilirubin, 776-, total iron-binding capacity, and percentage saturation innormal subjects, 603

magnesium, determination of, comparison of four methods, 220nitrazepam (Mogadon) in, determination of, 366non-esterified fatty acids in, estimation by colorimetric ultramicromethod, 567

protein-bound iodine estimations, screening test for, 530proteins, changes in relation to urinary tract involvement in spinabifida (P), 538

-, total, and protein fractions, ultramicro automation of (P), 538unsaturated iron-binding capacity, determination with radioactiveiron and magnesium carbonate, 183uric acid levels in uraemia, determination by enzymatic andcolorimetric methods, 192

SEVERN, M. See MANLEY, G., SEVERN, M., and HAWKSWORTH, J.Sex difference in leucocyte count, 691SHANSON, D.: A new medium for the investigation of salmonella

outbreaks (P), 791

SHEARMAN, D. J. C. See FINLAYSON, N. D. C., SHEARMAN, D. J. C.,SIMPSON, J. D., and GIRDWOOD, R. H.

SHETH, N. K., andPRANKERD, T. A.J.: Inherited thrombocytopeniawith thrombasthenia, 154

SHINTON, N. K., WILLIAMS, H.P., and THURSBY-PELHAM, D. C.: CongenitalHeinz body haemolytic anaemia due to haemoglobin Hammer-smith (P), 540

SHORTLAND-WEBB, W.R.: Proteus and coliform meningoencephalitisin neonates, 422

SIGNY, A. C.: Stefan Engel (Obituary) 420- See also GREEN, A. E., and SIGNY, A. G.SIMMONS, N. A.: An automated method for serum bilirubin determina-

tion, 196SIMPSON,J.D. See FINLAYSON, N.D. C., SHEARMAN,D.J. C., SIMPSON,

J. D., and GIRDWOOD, R. H.SINNIAH, R., and NEILL, D. W.: Serum iron, total iron-binding capacity,

and percentage saturation in normal subjects, 603Sjogren's disease, labial salivary gland biopsy in, 656Skeletal muscle, water, sodium, potassium, and chloride content in

health and disease, 555Skull, Gelligaer, porotic hyperostosis in, 753SMITH, D. S. See STRATTON, F., SMITH,I&.S., and RAWLINSON, V.1.SMITH, H. See FELL,G.S., SMITH, H., and HOWIE, R. A.SMITH,P.M., MIDDLETON,J. E., and WILLIAMS,R.: Effect of unconjugated

bilirubin on the estimation of serum iron by a modified Sanfordtechnique, 776

Sodium content of skeletal muscle in health and disease, 555-in chronic renal failure, 547Specimen identification for data processing, 250Spina bifida, urinary tract involvement in, serum protein changes in

relation to (P), 538SPITTLE, C. R., LANSDOWN, N.M., and HAWKEY, C. M.: Micro modifica-

tion of the dilute blood clot lysis time for determining fibrinolyticactivity, 780

Spur cell anaemia, role of lipoproteins in formation of, in cirrhosiof liver, 620

Sputum, liquefaction by pancreatin-trypsin solution for bacteriological examination, 531

Staphylococci and micrococci, coagulase-negative, antibiotic resistance of, 722lysozyme production by, frequency tested by plate method, 390

Staphylococcus albus strains from urinary tract, classification of, 93aureus, methicillin resistance in, screening test for detection of, 213-, penicillinase-forming strains and penicillinase-negative variants,resistance to cephaloridine, cephalothin, methicillin, and benzyl-penicillin, 75

Starch in dimethylsulphoxide for amylase determination, 764Stat-test for detection of significant bacteriuria, evaluation of, 443Steam sterilization, low-temperature, with formaldehyde, residual

formaldehyde after, 771Steatorrhoea, idiopathic, primary lymphadenopathy complicating

(P), 536Sterile quick-drying cabinet for culture plates, 670Sterilization with low-temperature steam and formaldehyde, residual

formaldehyde after, 771STEWART, A. E. See GOODWIN, C. S., and STEWART, A. E.STEWART, J. W. See CARTER, A., CROSLAND-TAYLOR, P. J., and STEWART,

J. W.STONE, W. D.: Cytochrome oxidase activity in the gastric mucosa of

patients with iron deficiency, 616STRATTON, F., SMITH, D. S., and RAWLINSON, V. I.: Value of gel filtration

on Sephadex G-200 in the analysis of blood group antibodies,708

STRAUB, P. W. See FELTEN, A. VON, STRAUB, P. W., and FRICK, P. G.Streptococci, 13-haemolytic, and C. albicans, presence and persistence

in vagina of, influence of oral contraceptives on (P), 791STRONG, R. See ACLAND, J. D., and STRONG, R.STUBBS, J. See SULLMAN, S. F., ZUCKERMAN, A. J., TAYLOR, P. E., and

STUBBS, J.SULLMAN, S. F., ZUCKERMAN, A. J., TAYLOR, P. E., and STUBBS, J.:

Tissue culture of adult liver biopsies (P), 793SYMMERS, W. ST. C., SR.: Survey of the eventual diagnosis in 600 cases

referred for a second histological opinion after an initial biopsydiagnosis of Hodgkin's disease, 650

226 cases referred for a second histologicalopinion after an initial biopsy diagnosis of reticulum cellsarcoma, 654

Symposium on Acute Respiratory Diseases, 682-- Detection of Cancer, 1st International, 681Syphilis in pregnancy, serodiagnosis with Reiter protein complement-

fixation test, 731primary, immunofluorescence method for diagnosis of, usingabsorption technique, 576

TAPP, E., and MORRISON, D.: Contiguous but dissimilar epithelialneoplasms of the urinary bladder, 332

TAYLOR, C. E. D., KERSHAW, J. W., and HEIMER, G. V.: An evaluation ofthe Technicon AutoAnalyzer for automating complement-fixationtests, 521

TAYLOR, G. See WARDLE, E. N., and TAYLOR, G.

Index

TAYLOR, P. E., and ZUCKERMAN, A. J.: Lack of production of interferingsubstances in infectious hepatitis (P), 794

-. See also SULLMAN, S. F., ZUCKERMAN, A. J., TAYLOR, P. E., andSTUBBS, J.

TAYLOR, P. J. CROSLAND-. See CROSLAND-TAYLOR, P. J.Telegraphy, facsimile. See Facsimile telegraphyTestis, tumours of, morphogenesis of, 71Tetrazolium medium in diagnosis of Candida species, 383Thalassaemia, haemoglobin D Los Angeles-beta, suppression of

haemoglobin A synthesis in, 508THEODOROPOULOS, G., MAKKOUS, A., and CONSTANTOULAKIS, M.:

Lymph node enlargement after a single massive infusion of irondextran, 492

Thiosemicarbazide-diacetyl monoxime procedure for determinationof urea, 527

THOMSON, J. A., BOYLE, 1. T., MCGIRR, E. M., MACDONALD, E. M., NICOL,J., and BROWN, i.: Evaluation of discordant laboratory data inpatients with thyroid disorders, 511

Thrombocytopenia, congenital, with thrombasthenia, 154Thromboplastin time test, partial, in long-term anticoagulant therapy

(P), 539THURSBY-PELHAM, D. C. See SHINTON, N. K., WILLIAMS, H. P., and

THURSBY-PELHAM, D. C.Thyroid carcinoma and Cushing's syndrome, 129-disorders, evaluation of discordant laboratory data in, 511-, plasmacytoma of, 661-status, assessment by free thyroxine index in pregnant women

and in patients taking oral contraceptives, 767TIGHE, J. R., CLARK, A. E., EISINGER, A. J., and JONES, N. F.: Renal biopsy:

an assessment of routine electron microscopy (P), 793-, -, and TURVEY, D. i.: Elastofibroma dorsi, 463TODD, G. M.: Stability of papain-cysteine-anti-D mixture on freeze

drying and on storage, 530TOMPSETT, S. L.: Nitrazepam (Mogadon) in blood serum and urine

and librium in urine, 366TORRANCE, J. D., CHARLTON, R. W., SCHMAMAN, A., LYNCH, S. R., and

BOTHWELL, T. H.: Storage iron in 'muscle', 495TOSELAND, P. A.: Specific determination of plasma and urinary lactose,

112Toxocara infections, detection of circulating antibody by indirect

fluorescent antibody test in, 449TOZER, R. A. See ROOME, A. P. C. H., and TOZER, R. A.Transplacental haemorrhage, significance of placental pathology in,

322Treponemes in films from suspected chancres, fluorescent technique

for demonstration of, 108Trichophyton rubrum infections, mycological tests in, 729Trimethoprim, laboratory and clinical studies of, 202TROTMAN, R. E., and DRASAR, B. S.: Electrically-heated inoculating

loop, 224Tumours, carcinoid, argentaffin and non-argentaffin, of appendix, 60-, 'non-endocrine', and thyroid carcinoma, associated with Cushing's

syndrome, 129-of testis, morphogenesis of, 71TURKINGTON, V. E. See GIBSON, G. L., JOHNSTON, H. P., and TURKINGTON,

V. E.TURVEY, D. J. See TIGHE, J. R., CLARK, A. E., and TURVEY, D. J.Typewriters, electric, in data processing, 279TYTGAT, G. See COLLEN, D., TYTGAT, G., and VERSTRAETE, M.

Uganda, Kaposi's sarcoma and granuloma pyogenicum in, com-parative study of, 119

Uraemia, haemostatic mechanism in, 406-, uric acid levels in, determination by enzymatic and colorimetric

methods, 192Urea, determination by modified diacetyl monoxime-thiosemi-

carbazide procedure, 527- in chronic renal failure, 541Uric acid levels in uraemia, determination by enzymatic and colori-

metric methods, 192Urinary and plasma lactose, specific determination of, 112- corticosteroids, multipupose gas chromatographic assay for, 372- tract involvement in spina bifida, serum protein changes in relation

to (P), 538- -, Staph. albus strains from, classification of, 93Urine, chelated iron in, determination of, 166-, collection from women for bacteriological examination (P), 539-, excretion patterns of glycosaminoglycans and glycoproteins in,

339- jaundiced, estimation of ferrioxamine in, 169- methylmalonic acid in, estimation by colorimetric method, 221

nitrazepam (Mogadon) and librium in, determination of, 366

803

Vagina, presence and persistence of C. albicans and 9-haemolyticstreptococci in, influence of oral contraceptives on (P), 791

Vaginal fluid, 6-phosphogluconate dehydrogenase assay in, effect ofblood on, 189

VALTERIS, G. J. See MUIR, G. G., and VALTERIS, G. J.VERSTRAETE, M. See COLLEN, D., TYTGAT, G., and VERSTRAETE, M.Villous pattern in small intestinal necropsy material, staining method

for examination of, 748Viruses, coding systems for data processing, 260Vitamin B12 absorption, assessment of serum 57Co cyanocobalamin

as index of (P), 792---, determination by whole body:counter, 595-- deficiency, cellular defect in, investigation of (P), 792--, radioisotopic assay of (L), 226-levels in chronic renal failure, 551

WARD, A. M.: Serum protein changes in relation to urinary tractinvolvement in spina bifida (P), 538

WARDLE, E. N., and TAYLOR, G.: Fibrin breakdown products andfibrinolysis in renal disease, 140

WARDROP, C., and HUTCHISON, H. E.: The possible physiologicalsignificance of the microangiopathic red cell form (P), 793

Water balance in chronic renal failure, 547- content of skeletal muscle in health and disease, 555WATERWORTH, P. M. See DARRELL, J. H., GARROD, L. P., and WATER-

WORTH, P. M.WAYTE, D. M.: Halo naevi (P), 537WEBB, W. R. SHORTLAND-. See SHORTLAND-WEBB, W. R.WEINFELD, A., LUNDIN, P., and LUNDVALL, O.: Significance for the

diagncsis of iron overload of histochemical and chemical ironin the liver of control subjects, 35

WELSHMAN, S. G., and MCKEE, G.: Screening test for an automatedprotein-bound iodine technique, 530

WERTLAKE, P. T., and WILLIAMS, T. W., JR.: Septicaemia caused byNeisseria flavescens, 437

WEST, H. F. See MURPHY, D., and WEST, H. F.White matter of central nervous system, spongy degeneration of,

associated with hyperglycinuria, 456WHITEHEAD, R.: Primary lymphadenopathy complicating idiopathic

steatorrhoea (P), 536-, and MASSARELLA, G. R.: Correlation between diabetic glomerulo-

sclerosis and hyalinization of the islets of Langerhans (P), 536Whole body counter in determination of vitamin B1, absorption, 595WILLIAMS, A. H. See FENTON, J. C. B., and WILLIAMS, A. H.WILLIAMS, E. D., MORALES, A. M., and HORN, R. C.: Thyroid carcinoma

and Cushing's syndrome: a report of two cases with a reviewof the common features of the 'non-endocrine' tumours, asso-ciated with Cushing's syndrome, 129

-. See also EVANS, D. J., and WILLIAMS, E. D.WILLIAMS, H. P. See SHINTON, N. K., WILLIAMS, H. P., and THURSBY-

PELHAM, D. C.WILLIAMS, J. A. See FLEAR, C. T. G., FLORENCE, i., and WILLIAMS, J. A.WILLIAMS, R. See SMITH, P. M., MIDDLETON, J. E., and WILLIAMS, R.WILLIAMS, R. E. O. See CORSE, J., and WILLIAMS, R. E. O.WILLIAMS, R. F., and BAMBURY, J. M.: Mechanical rotary device for

plating out bacteria on solid medium, 784WILLIAMS, T. W., JR. See WERTLAKE, P. T., and WILLIAMS, T. W., JR.WILLS, M. R.: Biochemical consequences of chronic renal failure: a

review, 541WILSON, J. F. See MACKENZIE, D. H., WILSON, J. F., and COOKE, K. B.WILSON, P. A., MCNICOL, G. P., and DOUGLAS A. S.: Effect of fibrinogen

degradation products on platelet aggregation, 147Wilson's disease, neutron activation analysis for copper in, 8- -, trace metals, in 1WOLMAN, L. See ROY, S., and WOLMAN, L.WOODRUFF, A. W. See BISSERU, B., and WOODRUFF, A. W.WOALLEDGE, S. M. See BAKER, L. R. I., BRAIN, M. C., AZZOPARDI, J. G.

and WORLLEDGE, S. M.WRIGHT, D. H.: Lipid content of malignant lymphomas, 643

ZANDREW, F. See LEE, C. L., ZANDREW, F., and DAVIDSOHN,ZILVA, J. F. See HOWORTH, P. J. N., and ZILVA, J. F.Zinc, plasma, measurements of, in health and disease, 359-,-,--,in malignant disease, 363ZUCKERMAN, A. J., KAY, H. E. M., and HOCKLEY, A. B.: Recovery of

human foetal liver cells after storage in liquid nitrogen, 109-. See also SULLMAN, S. F., ZUCKERMAN, A. J., TAYLOR, P. E., and

STUBBS, J.-. See also TAYLOR, P. E., and ZUCKERMAN, A. J.