The heterogeneity model gLgL VLVL g Ca V Ca C VmVm C = g L (V m -V L )+g Ca (V m -V Ca ) dV dt g Ca...
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The heterogeneity model g L V L g Ca V Ca C V m C = g L (V m -V L )+g Ca (V m -V Ca ) dV dt g Ca = g Ca m 3 h g Ca (mS/cm 2 ) g L (mS/cm 2 ) dh dt h inf (Vm)-h = h
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Transcript of The heterogeneity model gLgL VLVL g Ca V Ca C VmVm C = g L (V m -V L )+g Ca (V m -V Ca ) dV dt g Ca...
The heterogeneity model
gL
VL
gCa
VCa
C Vm
C = gL(Vm -VL)+gCa(Vm-VCa)dVdtgCa = gCa m3h
gCa (mS/cm2)
g L(m
S/c
m2 )
dhdt
hinf(Vm)-h= h
Reconstructing the phase diagram
The line connecting the two cells crosses the oscillating zone.
The combination of the average channel densities falls inside the oscillating or stable zone.
gCa (mS/cm2)
g L(m
S/c
m2 )
5 mV
100 ms
Timing of neuronal output by subthreshold oscillations
IV=I+II
V=IV-III
The timing of neuronal output is frequency dependent
