Emotions, Stress & Immunity

George F Solomon

情緒‧壓力與免疫

• 1960—Jonas SalkAll diseases are genetic, behavioral, nervous and immune

George Solomon—

add “Endocrine system”

所有疾病都是因為遺傳，行為，神經、及免疫 ．．．．

加內分泌系統

Immune System—1免疫 系通

液體式抗生素血液白血球即時對抗毒素

細菌等即時敏感分析

液體式抗生素血液白血球即時對抗毒素

細菌等即時敏感分析

Immune System –2免疫 系通

細主胞道低抗外侵細菌

或外來細包器官移值拖慢敏感反應

Immune & Nervous System免疫與神經系統

免疫系統 神經系統低抗破壞敏感 神經官能症

襲激自己

自體免疫性疾病 抑鬱症關節炎

Immune and Nervous System免疫與神經系統

• Both capable of learning

• Immunity –

Immune – immunization

Nervous – stress experiences

strengthens or weakens

• 1. Emotional upsets and distress affect severity of disease

• 2. Severe emotional and mental disorders accompanied by abnormality in immune system

• 3. Hormones regulated by CNS affect workings of the immune system

情緒波動應嚮病情

嚴重情緒或精神問題免疫系統亦出現不正常運作

激素也應嚮免疫系統

George Solomon—

4. Any manipulation on CNS have immunological effects

5. Stress events should affect immune system

.

任何中樞神經系統都有免疫影嚮

壓力事件應影嚮免疫

George Solomon—

6. cells in immune system should be responsive to hormones connected to the nervous system

7. any action on the immune system should be reflected in activities within the CNS

免疫系統細胞對與神經系統有關的激素有反應

任何對免疫系統的行動都會在中樞神經系統活動反影出來

George Solomon—

Personality and StressPerson with autoimmune diseases

Quiet Introvert Reliable ConscientiousRestricted to

expression of emotions (mainly anger)

ConformingSelf-sacrificingSensitive to criticism

Distant

Overactive

Busy

Stubborn

Rigid

Controlling

Pseudoindependent

Personality and StressPerson with autoimmune diseases

Physiological + Psychological

• People with rheumatoid arthritis

* those with autoantibody – emotionally healthier, less anxious, depressed or alienated

Rapidity— Inability to

express hostile feelings

Unresolved tensions

Loss of an important person

Schizophrenia –

higher levels of autoantibodies

Severe depressive mental illness – lower level of T-cells

• Hypothalamus – pituitary

--limbic

-- pituitary and thymus

Marvin SteinMt Sinai School of Medicine,

New York

• Husbands whose wives died of breast cancer

• 2 months after wives died, immune system depressed but by 4th month went back up

• The more openly the man griefed the quicker the return

• Those inability to mourn – suppression – fall ill or get cancer easier

Marvin SteinMt Sinai School of Medicine,

New York

Older folks• Physically and

mentally healthy elderly persons have remarkably intact, even superior immune function.