THE FAT CAT ATE THE BIG RAT THE FAT ATA TET HEB IGR AT

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Transcript of THE FAT CAT ATE THE BIG RAT THE FAT ATA TET HEB IGR AT

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THE FAT CAT ATE THE BIG RAT

THE FAT ATA TET HEB IGR AT

THE FAT ATA ATE THE BIG RAT

WT

Delete C

Insert A

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Action of amino-acyl tRNA synthetase

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mRNA is translated by ribosomes

Typical bacterial mRNA molecule - polycistronic

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polyribosome

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Hsp 70 family of chaperones mecdiate protein folding

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Hsp60, GroEL, TCP1 mediated protein folding Cellular pathway to monitor protein folding

The structure of the proteosomeControlled degredation of proteins - formation of ubiquitin ligase

Model for basis of prion diseasesscrapie (sheep)Creutzfeldt-Jacob disease (humans)bovine spongiform encephalopathy (cattle)