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The Eye in Systemic Disease. ● Numerous conditions have eye symptoms associated with them ●...
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Transcript of The Eye in Systemic Disease. ● Numerous conditions have eye symptoms associated with them ●...
The Eye in Systemic Disease
The Eye in Systemic Disease
● Numerous conditions have eye symptoms associated with them
● Different parts of the eye are associated with different syndrome
The Eye in Systemic Disease
● Structure of Talk:– Mind Map
Eye
Amaurosis
Fugax
CRAO Uveitis
Cataracts
Abnorm Eye
Movements
Pupillary Abnormali
ties
Retinal vessel disease
Common Eye Problems
Cataracts
Eye
CATARACTS
Metabolic
Other Systemic Diseases
Drug Induced
CATARACTS
Meta-bolic
DMG6PD
PFKD
CATARACTS
Metabolic
Other Systemic Diseases
MuscularDystroph
y
Derma-titis
NF 2
CATARACTS
Metabolic
Other Systemic Diseases
Drug Induced
Steroids
Common Eye Problems
Eye
Amaurosis
Fugax
CRAO Uveitis
Cataracts
Abnorm Eye
Movements
Pupillary Abnormali
ties
Retinal vessel disease
Common Eye Problems
Eye
Uveitis
Uveitis
Systemic Dis&
Syndromes
InfectionsInfestations
Uveitis
Systemic Dis&
Syndromes
Uveitis
Systemic Dis&
Syndromes
Sarcoid
BehcetsReiter's
AnkSpond
Crohn'sDis
UCJCA
Uveitis
Sarcoid
BehcetsReiter's
AnkSpond
Crohn'sDis
UCJCA
Polyarthritis
Systemic Dis&
Syndromes
Uveitis
Sarcoid
BehcetsReiter's
AnkSpond
Crohn'sDis
UCJCA
Systemic Dis&
Syndromes
Uveitis
Sarcoid
BehcetsReiter's
AnkSpond
Crohn'sDis UC
JCA
Systemic Dis&
Syndromes
Uveitis
Sar-coid
Beh-cetsReiter's
AnkSpond
UCJCA
Sacro-iliitis (also
spine)
Systemic Dis&
Syndromes
Crohn'sDis
UCJCA
Uveitis
Sarcoid
Behcets
Urethritis
Arthritis
Systemic Dis&
Syndromes
Reiter's
AnkSpond
Crohn'sDis
UCJCA
Uveitis
Sarcoid
Behcets
Overreaction ofImmune System
Systemic Dis&
Syndromes
Reiter's
AnkSpond
Crohn'sDis
UCJCA
Uveitis
Sarcoid
Beh-cetsReiter's
AnkSpond
Crohn'sDis
UCJCA
oral ulcers
Genital ulcersSkin
Lesions
Systemic Dis&
Syndromes
Uveitis
Sarcoid
BehcetsReiter's
AnkSpond
Crohn'sDis
UCJCA
Granulomas
Unknown AetiologySystemic
Dis&
Syndromes
Uveitis
Sarcoid
BehcetsReiter's
AnkSpond
Crohn'sDis
UCJCA
Systemic Dis&
Syndromes
Uveitis
Systemic Dis&
Syndromes
InfectionsInfestations
Uveitis
Infections
Infections
TB
CandidaHerpes Zoster
Uveitis
Systemic Dis&
Syndromes
InfectionsInfestations
Uveitis
Infestations
Infestations
Toxoplasmosis
Toxocariasis
Pneumocystosis
Common Eye Problems
Eye
Amaurosis
Fugax
CRAO Uveitis
Cataracts
Abnorm Eye
Movements
Pupillary Abnormali
ties
Retinal vessel disease
Common Eye Problems
Eye
Abnorm Eye
Movements
Common Eye Problems
Abnorm Eye
Movements
CVA
Aneurysm DM
Common Eye Problems
Eye
Amaurosis
Fugax
CRAO Uveitis
Cataracts
Abnorm Eye
Movements
Pupillary Abnormali
ties
Retinal vessel disease
Common Eye Problems
Eye
CRAO
CRAO
Source ofEmboli
Common Eye Problems
Eye
Amaurosis
Fugax
CRAO Uveitis
Cataracts
Abnorm Eye
Movements
Pupillary Abnormali
ties
Retinal vessel disease
Common Eye Problems
EyeRetinal vessel disease
Retinal vessel disease
DiabetesMellitus
Hypertension Hypercholesterolaemia
Retinal vessel disease
DiabetesMellitus
DiabetesMellitus
BackgroundRetinopathy
Pre-prolifRetionopa
thy
Proliferative
Retinopathy
Maculopathy
DiabetesMellitus
BackgroundRetinopathy
Pre-prolifRetionopa
thy
Proliferative
Retinopathy
Maculopathy
BackgroundRetinopathy
Dot Haemorrha
ges
Hard Exudates
NORMAL eyesight
-present in almost all who have had type 1 diabetes for 20 years -present in nearly 80 percent of those with type 2 disease for 20 years
Micro-aneurysms
DiabetesMellitus
Background
Retinopathy
Pre-prolifRetionopa
thy
Proliferative
Retinopathy
Maculopathy
DiabetesMellitus Pre-prolif
Retinopathy
Pre-prolifRetionopathy
Cotton WoolSpots
Venous Irregularity
NORMAL EYESIGHT
Pre-prolifRetionopathy
REFER!
50% of patients progress to
proliferative retinopathy within 1-2 years
DiabetesMellitus
Background
Retinopathy
Pre-prolifRetionopa
thy
Proliferative
Retinopathy
Maculopathy
DiabetesMellitus
Proliferative
Retinopathy
ProliferativeRetinopathy
Neo-vascularisa
tion
NVD
NVE
NORMALEYESIGHT,but threatened....
ProliferativeRetinopathy
REFER!
DiabetesMellitus
Background
Retinopathy
Pre-prolifRetino-pathy
ProliferativeRetinopathy
Maculopathy
DiabetesMellitusMaculopathy
Maculopathy
Early and
Diffuse
Severe and
Ischaemic
EYESIGHTAFFECTED
Maculopathy
REFER!
Retinal vessel disease
DiabetesMellitus
Hyper-tension
Hypercholest-
erolaemia
Retinal vessel disease
Hyper-tension
Hypertension
Grade I
Grade II
Grade III
Grade IV
Hypertension
Grade I
Grade II
Grade III
Grade IV
Hypertension
Grade I
Grade II
Grade III
Grade IV
Hypertension
Grade I
Grade II
Grade III
Grade IV
Haemorr-
hages
CottonWoolSpots
Hypertension
Grade I
Grade II
Grade III
Grade IV
Hypertension
Grade I
Grade II
Grade III
Grade IV
SilverWiring
Hypertension
Grade I
Grade II
Grade III
Grade IV
A-V Nipping
Hypertension
Grade I
Grade II
Grade III
Grade IV
Haemorr-
hages
CottonWoolSpots
Hypertension
Grade I
Grade II
Grade III
Grade IV
Papill-oedem
a
Retinal vessel disease
DiabetesMellitus
Hyper-tension
Hypercholest-erolaemia
Common Eye Problems
Eye
Amaurosis
Fugax
CRAO Uveitis
Cataracts
Abnorm Eye
Movements
Pupillary Abnormali
ties
Retinal vessel disease
Common Eye Problems
Eye
Amaurosis
Fugax
CRAO Uveitis
Cataracts
Abnorm Eye
Movements
Pupillary Abnormali
ties
Retinal vessel disease
Amaurosis Fugax = painless,
transient (secs/mins), partial or
complete
Amaurosis Fugax
EmbolicEmbolic
Vasospastic/
Haemodynamic
Neourologic
Ocular
Idiopathic
Amaurosis Fugax
EmbolicEmbolic
Vasospastic/
Haemodynamic
Neuro-logic
Ocular
Idiopathic
OpticNeuritis
(MS)
Migraine
Amaurosis Fugax
Embolic
Vasospastic/
Haemodynamic
Neourologic
Ocular
Idiopathic
TIA(cardiac/carotid/other)
Amaurosis Fugax
EmbolicEmbolic
Vasospastic/
Haemo-dynamic
Neuro-logic
Ocular
Idio-pathicTemp
Arteritis
Common Eye Problems
Eye
Amaurosis
Fugax
CRAO Uveitis
Cataracts
Abnorm Eye
Movements
Pupillary Abnormali
ties
Retinal vessel disease
Common Eye Problems
Eye
Amaurosis
Fugax
CRAO Uveitis
Cataracts
Abnorm Eye
Movements
Pupillary Abnormali
ties
Retinal vessel disease
PupillaryDefects
Horner'sSyndrom
e
CVA/SOL
Adie’s Pupil
Common Eye Problems
Eye
Amaurosis
Fugax
CRAO Uveitis
Cataracts
Abnorm Eye
Movements
Pupillary Abnormali
ties
Retinal vessel disease