The Essentials of Pain Management
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LannyLanny
dr. Laniyati Hamijoyo SpPD-KR. M.Kes
Pendidikan:
1994 : FK Universitas Atma Jaya, Jakarta
1996 : Internship di CWZ Nijmegen-Netherland
2005 : Spesialis Penyakit Dalam FK.UNPAD, Bandung2005 : Magister kesehatan FK. UNPAD, Bandung
2007 : Subspesialisasi Reumatologi di Univ.Santo Tomas Manila
2008 : Adaptasi Konsultan Reumatologi FKUI,Jakarta
Organisasi: Anggota:
IRA, PAPDI, PRA, IDI, APLAR
Penghargaan:
JCR, APLAR, EULAR, TIR, PRA
Curriculum Vitae:
Staf pengajar Departemen Ilmu Penyakit Dalam FK UNPAD/RS Hasan Sadikin Bandung
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The Essentials ofThe Essentials ofPain ManagementPain Management
Laniyati HamijoyoLaniyati Hamijoyo
Divisi Reumatologi Departemen Ilmu Penyakit DalamDivisi Reumatologi Departemen Ilmu Penyakit Dalam
FK Universitas Padjadjaran/ RS Hasan Sadikin BandungFK Universitas Padjadjaran/ RS Hasan Sadikin Bandung
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Case # 1
Mr B 23/M Acute pain 2 hours ago
On his right ankle
History of falling during play
basketball 2 hour ago
What is the diagnosis?
What will you suggest?
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Case # 1
Ms. D 35/F
Pain on both hands
Since 2 months
Swollen
What is the diagnosis?
What medicine will you start
on her?
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LannyLanny
Case # 2
Mrs. L 55/F
Sharp and burned like pain
on her fingers especially
right hand
Since 3 months
Worse in the morning
History of type 2 DM
What is her diagnosis?
Therapy?
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Pain
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PainPain
How to diagnose?
Therapy?
Whichmedicine?
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Problems related to
healthcare professionals
Inadequate knowledge
Poor assessment
Concern about regulation of controlled substances
Fear of patient addiction
Concerns of side effects of analgesics
Concerns about patients tolerant to analgesics
Barriers to effective pain managementBarriers to effective pain management
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Problems related to
patients
Reluctance to report Fear that pain means disease is worse
Reluctance about taking pain medicines
Concerns of being tolerant to medicines
Poor adherence
Worries about unmanageable side effects
Barriers to effective pain managementBarriers to effective pain management
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Problems related to
healthcare system
Cost
Reimbursement
Restrictive regulation
Availability
Barriers to effective pain managementBarriers to effective pain management
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Definition of pain1
Assessment and diagnosisof pain2
3 Management and monitoring of pain
Outline the essentials of painOutline the essentials of pain
managementmanagement
1
2
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Definition of painDefinition of pain
An unpleasant sensory and emotional
experience associated with actual or
potential tissue damage, or described
in terms of such damage IASP
In reality,
its what the patient says it is.
Merskey H, Bogduk N. 2nded Seattle, WA: IASP Press; 1994.
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Physiology of Pain PerceptionPhysiology of Pain Perception
InjuryInjury
DescendingDescendingPathwayPathway
PeripheralPeripheralNerveNerve
DorsalDorsalRootRootGanglionGanglion
C-FiberC-Fiber
A-beta FiberA-beta Fiber
A-delta FiberA-delta Fiber
AscendingAscendingPathwaysPathways
DorsalDorsalHornHorn
BrainBrain
Spinal CordSpinal Cord
Adapted with permission from WebMD Scientific AmericanAdapted with permission from WebMD Scientific American MedicineMedicine..
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Injury-induced Pain:Injury-induced Pain:
Patient FactorsPatient Factors
McQuay H. BMJ 1997;314:1531.
Individual
variation in
response to injury:
physiological,behavioral,
and cultural
Individual
variation in
response totreatment
Injury
Complaint of pain
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Definition of pain1
Assessment and diagnosis of pain2
3 Management and monitoring of pain
OutlineOutline
1
2
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Assessment of painssessment of painGoals:
Achieve diagnosis of pain and underlyingAchieve diagnosis of pain and underlying
disorderdisorder
Characterizing and quantifying the painCharacterizing and quantifying the pain
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Achieve diagnosis andAchieve diagnosis and
underlying disorderunderlying disorder
History takingHistory taking
Pattern : onset, duration, frequency
Area : location, topography
Intensity: level
Nature : description, history of
similar episodes,intervention & what helped
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Question to evaluate painQuestion to evaluate pain
P-Q-R-S-T formatProvocation How the injury occurred & what activities
the pain, exacerbating and alleviating factors
Quality characteristics of pain (tingling, burning, dull)
Referral/Radiation
Referred site distant to damaged tissue thatdoes not follow the course of a peripheralnerve.
Radiating follows peripheral nerve; diffuse
Severity How bad is it? Pain scale
Timing When does it occur? p.m., a.m., before, during,after activity, all the time
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Pain assessment toolsPain assessment tools
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Pain assessment toolsPain assessment tools
Brief pain inventory
Patients rate pain intensity and its effect ongeneral activity, mood, ability to walk, work,relationships, sleep, and enjoyment of life
McGill Pain questionnaire
Patients rank pain in words sets that are groupedin 4 main categories: sensory, affect, evaluative,
and miscellaneous
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Physical examinationPhysical examination
General PE: Vital sign
Regional examination
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Musculoskeletal examinationMusculoskeletal examination
Inspection: look for redness,
swelling, deformity
Palpation : Test for warmness
Test for deep/ superficial
muscle tenderness
Range of motion
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Neurological examinationNeurological examination
Mental status
Cranial nerves
Motor function: weakness, ataxia Sensory function
Reflexes
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Classify PainClassify Pain
AcuteAcute
Recent onsetRecent onset
Limited durationLimited duration
The cause is generally knownThe cause is generally known
resolution of underlyingresolution of underlying
cause, self limitedcause, self limited
ChronicChronic
Persist for > 3- 6 monthsPersist for > 3- 6 months
Persist at least 1 month beyondPersist at least 1 month beyond
the usual course of acute painthe usual course of acute pain
Associated with chronicAssociated with chronic
pathologic processpathologic process
Recurs at relatively short intervalRecurs at relatively short interval
duration:
htt ://www. medsca e.org 2011
http://www/http://www/http://www/ -
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NociceptiveNociceptive Irritation/Irritation/
TissueTissueinjuryinjury
Classify the PainClassify the Pain
Malfunction
on peripheral /
central nerves
PsychologicPsychologic
factorfactor
NeuropathicNeuropathic
PsychogenicPsychogenic Nociceptive &Nociceptive &
neuropathicneuropathicMixedMixed
mechanism:
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Type of painType of pain
Pain
Nociceptive
Visceral Somatic
Pleurisy
Appendicitis
cholecystitis
Poorly localized
Cramping, dull
well localized
Variably
Skin, muscle
Soft tissue,
bone
Neuropathic
Abn neural activity
due to injury or
disease of the
nervous system
Thalamic pain
Trigeminal neuralgia
Diabetic neuropathy
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Nociceptive VS neuropathic painNociceptive VS neuropathic pain
Neuropathic painInitiated or caused by primary
lesion or dysfunction in the
nervous system
Nociceptive painCaused by activity in neural
pathway in response to
potentially tissue- damaging
stimuli
Postoperative
pain
Mechanical LBP
Sport / exercise
injuries
Sickle cell crisis
ARTHRITIS PHN
Neuropathic LBP
Distal
polyneuropathy
(e.g. diabetic)
Central post
stroke pain
Trigeminal
neuralgia
CRPS
International Association for the Study of Pain. IASP Pain Terminology.Raja et al. in Wall PD, Melzack R (Eds). Textbook of pain. 4th Ed. 1999.;11-57
Mixed painCaused by a combination of
both primary injury or
secondary effects
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Pain characteristicPain characteristic
NociceptiveNociceptive
Focal/ diffuse painFocal/ diffuse pain
Sharp, dull, acheSharp, dull, ache
with sign of inflammationwith sign of inflammation
usually acuteusually acute
Often decrease over timeOften decrease over time
NeuropathicNeuropathic
Regional/ dermatomalRegional/ dermatomal
Burning, tingling, numbness,Burning, tingling, numbness,
needle prick painneedle prick pain
Often persists / worsen overOften persists / worsen over
timetime
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Pain characteristicPain characteristic
NociceptiveNociceptive
Alodinia/ hyperalgesiaAlodinia/ hyperalgesia
MS regional pain (arthritis,MS regional pain (arthritis,
bursitis, tenosynovitis, etc)bursitis, tenosynovitis, etc)
Post traumatic pain , fracturePost traumatic pain , fracture
Inflammation painInflammation pain
Bone metastasesBone metastases
NSAIDs often workNSAIDs often work, opiods, opiods
effective, adjuvant and topicaleffective, adjuvant and topical
analgesics somewhat effectiveanalgesics somewhat effective
NeuropathicNeuropathic
Peripheral neuropathic pain:Peripheral neuropathic pain:
- post herpetic neuralgia- post herpetic neuralgia
- diabetic neuropathic- diabetic neuropathic
- radiculapathic pain etc- radiculapathic pain etc
- metastases on plexus- metastases on plexus
Central neuropathic painCentral neuropathic pain
NSAIDs not effective, opioidNSAIDs not effective, opioid
less effective, adjuvant andless effective, adjuvant and
topical analgesics somewhattopical analgesics somewhat
effectiveeffective
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Evaluate the functional statusEvaluate the functional status
How does it affect physical function
and work (ADLs)?
How does it affect social andmental functioning?
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Evaluate the painEvaluate the pain
Identify comorbid conditionsIdentify comorbid conditions
Identify past medical historyIdentify past medical history
Family historyFamily history
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Additional examinationAdditional examination
Imaging
Laboratory
Psychosocial
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Identify Pain Treatment OptionsIdentify Pain Treatment Options
Non-Drug Therapies
Drug Therapies
More Invasive Therapies
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Pain Treatment Continuum
Least
invasive
Most
invasive
Psychological/physical approaches
Topical medications
*Consider referral if previous treatments were unsuccessful.
Systemic medications*
Interventional techniques*
Continuumnot related to efficacy
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Non-Drug TherapiesNon-Drug Therapies
Ice/Heat
Exercise/Rest
Physical Therapy
Chiropractic Care
Acupuncture
TENS Units
Behavioral Therapy
And Many More.
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Drugs for PainDrugs for Pain
Non-Opioid Analgesics Acetaminophen
Salicylates and Non-Selective NSAIDS
Selective COX-2 Inhibitors
Adjuvant Analgesics Antidepressants
Anticonvulsants
Topicals, Muscle Relaxants, and Others Opioids
Short- and long-acting formulations
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WHO (World Health Organization) Three-WHO (World Health Organization) Three-
Step Analgesic LadderStep Analgesic Ladder
Non-opioid
+ Adjuvant
Pain
Pain persisting or increasing
Opioid for mild to moderate pain
+ Non-opioid
+ Adjuvant
Pain persisting or increasing
Opioid for moderate to severe pain
+ Non-opioid
+ Adjuvant
Satisfactory Symptom Management
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WHO3-STEP
LADDER SEVERE3
MorphineHydromorphone
MethadoneOxycodone
Fentanyl
+/- Adjuvants
MODERATE3
A/CodeineA/Hydrocodone
A/Oxycodone
Tramadol+/- Adjuvants
MILD3
ASA/NSAIDS
AcetaminophenCox-3
+/- Adjuvants
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Bio-psycho-social in pain managementBio-psycho-social in pain management
Pain Behaviors
Suffering
Pain
Perception
Nociception
Local block
NSAIDs
Surgery
Physical modalities
Opioid
Adjuvants
NSAIDs?
Acetaminophene
Neural augmentation
Ablative surgery
Anti-depressants /psychotropics
Relaxation
Spiritual
Cognitive therapies
Functional restoration
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Some More Invasive TherapiesSome More Invasive Therapies
Trigger Point Injections
Intra-arthricular Injections
Regional Nerve Blocks
Epidural Injection
Various Surgeries
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Evaluation of pain managementEvaluation of pain management
Follow upFollow up::
- reassessed pain- reassessed pain
- functional improvement- functional improvement
- side effect therapy- side effect therapy- adherence to therapy- adherence to therapy
Educate patientsEducate patients::
- about the cause of pain- about the cause of pain
- set appropriate expectations of- set appropriate expectations oftreatmenttreatment
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Case # 1
Mr B 23/M Acute pain 2 hours ago
On his right ankle
History of falling during play
basketball 2 hour ago
What is the diagnosis?
PE: Warmth, swelling, painlimited range of motion
What will you suggest?
Pattern : onset, duration, frequency
Area : location, topography
Intensity: level
Nature : description, history of
similar episodes,
intervention & what helped
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LannyLanny
Case # 1
Ms. D 35/F
Pain on both hands
Since 2 months
Swollen, tender. Warm,morning stiffness
Lab: RF (+), ESR
What is the diagnosis?
What medicine will you starton her?
Pattern : onset, duration, frequency
Area : location, topography
Intensity: level
Nature : description, history of
similar episodes,intervention & what helped
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LannyLanny
Case # 2
Mrs. L 55/F
Sharp and burned like pain
on her fingers especially
right hand
Since 3 months
Worse in the morning
History of type 2 DM
Test: Tinel (+), Phallen (+)
What is her diagnosis?
Therapy?
Pattern : onset, duration, frequency
Area : location, topography
Intensity: level
Nature : description, history of
similar episodes,
intervention & what helped
S f P ti l A h tS f P ti l A h t
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Summary of a Practical Approach toSummary of a Practical Approach to
Pain ManagementPain Management
1. Evaluate and treat the underlying
cause.
2. Evaluate and treat the pain itself.
3. Listen to and trust your patients.4. Use all the resources at your disposal.
5. Re-evaluate the treatment
6. Refer if you get stuck
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