The Essentials of Pain Management

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    LannyLanny

    dr. Laniyati Hamijoyo SpPD-KR. M.Kes

    Pendidikan:

    1994 : FK Universitas Atma Jaya, Jakarta

    1996 : Internship di CWZ Nijmegen-Netherland

    2005 : Spesialis Penyakit Dalam FK.UNPAD, Bandung2005 : Magister kesehatan FK. UNPAD, Bandung

    2007 : Subspesialisasi Reumatologi di Univ.Santo Tomas Manila

    2008 : Adaptasi Konsultan Reumatologi FKUI,Jakarta

    Organisasi: Anggota:

    IRA, PAPDI, PRA, IDI, APLAR

    Penghargaan:

    JCR, APLAR, EULAR, TIR, PRA

    Curriculum Vitae:

    Staf pengajar Departemen Ilmu Penyakit Dalam FK UNPAD/RS Hasan Sadikin Bandung

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    The Essentials ofThe Essentials ofPain ManagementPain Management

    Laniyati HamijoyoLaniyati Hamijoyo

    Divisi Reumatologi Departemen Ilmu Penyakit DalamDivisi Reumatologi Departemen Ilmu Penyakit Dalam

    FK Universitas Padjadjaran/ RS Hasan Sadikin BandungFK Universitas Padjadjaran/ RS Hasan Sadikin Bandung

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    Case # 1

    Mr B 23/M Acute pain 2 hours ago

    On his right ankle

    History of falling during play

    basketball 2 hour ago

    What is the diagnosis?

    What will you suggest?

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    Case # 1

    Ms. D 35/F

    Pain on both hands

    Since 2 months

    Swollen

    What is the diagnosis?

    What medicine will you start

    on her?

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    Case # 2

    Mrs. L 55/F

    Sharp and burned like pain

    on her fingers especially

    right hand

    Since 3 months

    Worse in the morning

    History of type 2 DM

    What is her diagnosis?

    Therapy?

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    LannyLanny

    Pain

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    PainPain

    How to diagnose?

    Therapy?

    Whichmedicine?

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    Problems related to

    healthcare professionals

    Inadequate knowledge

    Poor assessment

    Concern about regulation of controlled substances

    Fear of patient addiction

    Concerns of side effects of analgesics

    Concerns about patients tolerant to analgesics

    Barriers to effective pain managementBarriers to effective pain management

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    Problems related to

    patients

    Reluctance to report Fear that pain means disease is worse

    Reluctance about taking pain medicines

    Concerns of being tolerant to medicines

    Poor adherence

    Worries about unmanageable side effects

    Barriers to effective pain managementBarriers to effective pain management

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    Problems related to

    healthcare system

    Cost

    Reimbursement

    Restrictive regulation

    Availability

    Barriers to effective pain managementBarriers to effective pain management

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    Definition of pain1

    Assessment and diagnosisof pain2

    3 Management and monitoring of pain

    Outline the essentials of painOutline the essentials of pain

    managementmanagement

    1

    2

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    Definition of painDefinition of pain

    An unpleasant sensory and emotional

    experience associated with actual or

    potential tissue damage, or described

    in terms of such damage IASP

    In reality,

    its what the patient says it is.

    Merskey H, Bogduk N. 2nded Seattle, WA: IASP Press; 1994.

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    Physiology of Pain PerceptionPhysiology of Pain Perception

    InjuryInjury

    DescendingDescendingPathwayPathway

    PeripheralPeripheralNerveNerve

    DorsalDorsalRootRootGanglionGanglion

    C-FiberC-Fiber

    A-beta FiberA-beta Fiber

    A-delta FiberA-delta Fiber

    AscendingAscendingPathwaysPathways

    DorsalDorsalHornHorn

    BrainBrain

    Spinal CordSpinal Cord

    Adapted with permission from WebMD Scientific AmericanAdapted with permission from WebMD Scientific American MedicineMedicine..

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    Injury-induced Pain:Injury-induced Pain:

    Patient FactorsPatient Factors

    McQuay H. BMJ 1997;314:1531.

    Individual

    variation in

    response to injury:

    physiological,behavioral,

    and cultural

    Individual

    variation in

    response totreatment

    Injury

    Complaint of pain

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    Definition of pain1

    Assessment and diagnosis of pain2

    3 Management and monitoring of pain

    OutlineOutline

    1

    2

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    Assessment of painssessment of painGoals:

    Achieve diagnosis of pain and underlyingAchieve diagnosis of pain and underlying

    disorderdisorder

    Characterizing and quantifying the painCharacterizing and quantifying the pain

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    Achieve diagnosis andAchieve diagnosis and

    underlying disorderunderlying disorder

    History takingHistory taking

    Pattern : onset, duration, frequency

    Area : location, topography

    Intensity: level

    Nature : description, history of

    similar episodes,intervention & what helped

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    Question to evaluate painQuestion to evaluate pain

    P-Q-R-S-T formatProvocation How the injury occurred & what activities

    the pain, exacerbating and alleviating factors

    Quality characteristics of pain (tingling, burning, dull)

    Referral/Radiation

    Referred site distant to damaged tissue thatdoes not follow the course of a peripheralnerve.

    Radiating follows peripheral nerve; diffuse

    Severity How bad is it? Pain scale

    Timing When does it occur? p.m., a.m., before, during,after activity, all the time

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    Pain assessment toolsPain assessment tools

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    Pain assessment toolsPain assessment tools

    Brief pain inventory

    Patients rate pain intensity and its effect ongeneral activity, mood, ability to walk, work,relationships, sleep, and enjoyment of life

    McGill Pain questionnaire

    Patients rank pain in words sets that are groupedin 4 main categories: sensory, affect, evaluative,

    and miscellaneous

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    Physical examinationPhysical examination

    General PE: Vital sign

    Regional examination

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    Musculoskeletal examinationMusculoskeletal examination

    Inspection: look for redness,

    swelling, deformity

    Palpation : Test for warmness

    Test for deep/ superficial

    muscle tenderness

    Range of motion

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    Neurological examinationNeurological examination

    Mental status

    Cranial nerves

    Motor function: weakness, ataxia Sensory function

    Reflexes

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    Classify PainClassify Pain

    AcuteAcute

    Recent onsetRecent onset

    Limited durationLimited duration

    The cause is generally knownThe cause is generally known

    resolution of underlyingresolution of underlying

    cause, self limitedcause, self limited

    ChronicChronic

    Persist for > 3- 6 monthsPersist for > 3- 6 months

    Persist at least 1 month beyondPersist at least 1 month beyond

    the usual course of acute painthe usual course of acute pain

    Associated with chronicAssociated with chronic

    pathologic processpathologic process

    Recurs at relatively short intervalRecurs at relatively short interval

    duration:

    htt ://www. medsca e.org 2011

    http://www/http://www/http://www/
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    NociceptiveNociceptive Irritation/Irritation/

    TissueTissueinjuryinjury

    Classify the PainClassify the Pain

    Malfunction

    on peripheral /

    central nerves

    PsychologicPsychologic

    factorfactor

    NeuropathicNeuropathic

    PsychogenicPsychogenic Nociceptive &Nociceptive &

    neuropathicneuropathicMixedMixed

    mechanism:

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    LannyLanny

    Type of painType of pain

    Pain

    Nociceptive

    Visceral Somatic

    Pleurisy

    Appendicitis

    cholecystitis

    Poorly localized

    Cramping, dull

    well localized

    Variably

    Skin, muscle

    Soft tissue,

    bone

    Neuropathic

    Abn neural activity

    due to injury or

    disease of the

    nervous system

    Thalamic pain

    Trigeminal neuralgia

    Diabetic neuropathy

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    Nociceptive VS neuropathic painNociceptive VS neuropathic pain

    Neuropathic painInitiated or caused by primary

    lesion or dysfunction in the

    nervous system

    Nociceptive painCaused by activity in neural

    pathway in response to

    potentially tissue- damaging

    stimuli

    Postoperative

    pain

    Mechanical LBP

    Sport / exercise

    injuries

    Sickle cell crisis

    ARTHRITIS PHN

    Neuropathic LBP

    Distal

    polyneuropathy

    (e.g. diabetic)

    Central post

    stroke pain

    Trigeminal

    neuralgia

    CRPS

    International Association for the Study of Pain. IASP Pain Terminology.Raja et al. in Wall PD, Melzack R (Eds). Textbook of pain. 4th Ed. 1999.;11-57

    Mixed painCaused by a combination of

    both primary injury or

    secondary effects

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    Pain characteristicPain characteristic

    NociceptiveNociceptive

    Focal/ diffuse painFocal/ diffuse pain

    Sharp, dull, acheSharp, dull, ache

    with sign of inflammationwith sign of inflammation

    usually acuteusually acute

    Often decrease over timeOften decrease over time

    NeuropathicNeuropathic

    Regional/ dermatomalRegional/ dermatomal

    Burning, tingling, numbness,Burning, tingling, numbness,

    needle prick painneedle prick pain

    Often persists / worsen overOften persists / worsen over

    timetime

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    Pain characteristicPain characteristic

    NociceptiveNociceptive

    Alodinia/ hyperalgesiaAlodinia/ hyperalgesia

    MS regional pain (arthritis,MS regional pain (arthritis,

    bursitis, tenosynovitis, etc)bursitis, tenosynovitis, etc)

    Post traumatic pain , fracturePost traumatic pain , fracture

    Inflammation painInflammation pain

    Bone metastasesBone metastases

    NSAIDs often workNSAIDs often work, opiods, opiods

    effective, adjuvant and topicaleffective, adjuvant and topical

    analgesics somewhat effectiveanalgesics somewhat effective

    NeuropathicNeuropathic

    Peripheral neuropathic pain:Peripheral neuropathic pain:

    - post herpetic neuralgia- post herpetic neuralgia

    - diabetic neuropathic- diabetic neuropathic

    - radiculapathic pain etc- radiculapathic pain etc

    - metastases on plexus- metastases on plexus

    Central neuropathic painCentral neuropathic pain

    NSAIDs not effective, opioidNSAIDs not effective, opioid

    less effective, adjuvant andless effective, adjuvant and

    topical analgesics somewhattopical analgesics somewhat

    effectiveeffective

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    Evaluate the functional statusEvaluate the functional status

    How does it affect physical function

    and work (ADLs)?

    How does it affect social andmental functioning?

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    Evaluate the painEvaluate the pain

    Identify comorbid conditionsIdentify comorbid conditions

    Identify past medical historyIdentify past medical history

    Family historyFamily history

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    Additional examinationAdditional examination

    Imaging

    Laboratory

    Psychosocial

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    Identify Pain Treatment OptionsIdentify Pain Treatment Options

    Non-Drug Therapies

    Drug Therapies

    More Invasive Therapies

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    Pain Treatment Continuum

    Least

    invasive

    Most

    invasive

    Psychological/physical approaches

    Topical medications

    *Consider referral if previous treatments were unsuccessful.

    Systemic medications*

    Interventional techniques*

    Continuumnot related to efficacy

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    Non-Drug TherapiesNon-Drug Therapies

    Ice/Heat

    Exercise/Rest

    Physical Therapy

    Chiropractic Care

    Acupuncture

    TENS Units

    Behavioral Therapy

    And Many More.

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    Drugs for PainDrugs for Pain

    Non-Opioid Analgesics Acetaminophen

    Salicylates and Non-Selective NSAIDS

    Selective COX-2 Inhibitors

    Adjuvant Analgesics Antidepressants

    Anticonvulsants

    Topicals, Muscle Relaxants, and Others Opioids

    Short- and long-acting formulations

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    WHO (World Health Organization) Three-WHO (World Health Organization) Three-

    Step Analgesic LadderStep Analgesic Ladder

    Non-opioid

    + Adjuvant

    Pain

    Pain persisting or increasing

    Opioid for mild to moderate pain

    + Non-opioid

    + Adjuvant

    Pain persisting or increasing

    Opioid for moderate to severe pain

    + Non-opioid

    + Adjuvant

    Satisfactory Symptom Management

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    WHO3-STEP

    LADDER SEVERE3

    MorphineHydromorphone

    MethadoneOxycodone

    Fentanyl

    +/- Adjuvants

    MODERATE3

    A/CodeineA/Hydrocodone

    A/Oxycodone

    Tramadol+/- Adjuvants

    MILD3

    ASA/NSAIDS

    AcetaminophenCox-3

    +/- Adjuvants

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    Bio-psycho-social in pain managementBio-psycho-social in pain management

    Pain Behaviors

    Suffering

    Pain

    Perception

    Nociception

    Local block

    NSAIDs

    Surgery

    Physical modalities

    Opioid

    Adjuvants

    NSAIDs?

    Acetaminophene

    Neural augmentation

    Ablative surgery

    Anti-depressants /psychotropics

    Relaxation

    Spiritual

    Cognitive therapies

    Functional restoration

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    Some More Invasive TherapiesSome More Invasive Therapies

    Trigger Point Injections

    Intra-arthricular Injections

    Regional Nerve Blocks

    Epidural Injection

    Various Surgeries

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    Evaluation of pain managementEvaluation of pain management

    Follow upFollow up::

    - reassessed pain- reassessed pain

    - functional improvement- functional improvement

    - side effect therapy- side effect therapy- adherence to therapy- adherence to therapy

    Educate patientsEducate patients::

    - about the cause of pain- about the cause of pain

    - set appropriate expectations of- set appropriate expectations oftreatmenttreatment

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    Case # 1

    Mr B 23/M Acute pain 2 hours ago

    On his right ankle

    History of falling during play

    basketball 2 hour ago

    What is the diagnosis?

    PE: Warmth, swelling, painlimited range of motion

    What will you suggest?

    Pattern : onset, duration, frequency

    Area : location, topography

    Intensity: level

    Nature : description, history of

    similar episodes,

    intervention & what helped

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    LannyLanny

    Case # 1

    Ms. D 35/F

    Pain on both hands

    Since 2 months

    Swollen, tender. Warm,morning stiffness

    Lab: RF (+), ESR

    What is the diagnosis?

    What medicine will you starton her?

    Pattern : onset, duration, frequency

    Area : location, topography

    Intensity: level

    Nature : description, history of

    similar episodes,intervention & what helped

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    Case # 2

    Mrs. L 55/F

    Sharp and burned like pain

    on her fingers especially

    right hand

    Since 3 months

    Worse in the morning

    History of type 2 DM

    Test: Tinel (+), Phallen (+)

    What is her diagnosis?

    Therapy?

    Pattern : onset, duration, frequency

    Area : location, topography

    Intensity: level

    Nature : description, history of

    similar episodes,

    intervention & what helped

    S f P ti l A h tS f P ti l A h t

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    Summary of a Practical Approach toSummary of a Practical Approach to

    Pain ManagementPain Management

    1. Evaluate and treat the underlying

    cause.

    2. Evaluate and treat the pain itself.

    3. Listen to and trust your patients.4. Use all the resources at your disposal.

    5. Re-evaluate the treatment

    6. Refer if you get stuck

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