The Clinical Translational Science Ontology Affinity Group
Transcript of The Clinical Translational Science Ontology Affinity Group
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The Clinical and Translational
Science Ontology Affinity Group
William R. Hogan, MD, MS
March 19, 2013
AMIA Translational BioinformaticsSummit
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What is it?
Technically speaking, an affinity group of the
Informatics Key Function Committee of the
CTSA Consortium
A group of people interested in pursuing
answers to the question how can ontologies
best enable translational science?
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ONE NEED NOT BE A CTSA CONSORTIUMMEMBER TO PARTICIPATE
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October 2010
Hogan and Scheuermann hatch idea at dinner duringIKFC meeting
Spring 2011Initial proposal takes shape, distributed to folks forfeedback
Winter (of discontent) 2011-2012
Proposal submitted to Operations Committee of IKFCand returned with questions and request for revisionsand clarification
History
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April 2012 First Clinical and Translational Science Ontology
Workshop held in Baltimore, MD
Participants enthusiastic about forming ontology-related AG in IKFC
Given takeover of CTSA Consortium support by C4,old AG proposal forms no longer in use
Proposal split into elevator pitch and operations
documents July 2012
Elevator pitch and operations documents submitted toIKFC Operations Committee
History (continued)
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November 2012
C4 and IKFC Operations Committee member inform
Hogan that the Clinical and Translational Science
Ontology Affinity Group (CTSO-AG) is approved!
December 2012
C4 sets up infrastructure for CTSO-AG on
ctsacentral.org
CTSO-AG keeps Google Group for inclusion of
members outside Consortium
History (continued)
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January 2013
First CTSO-AG monthly call held
February 2013
Second Clinical and Translational Science OntologyWorkshop held in Orlando, Florida (sponsored byTranslational Research Institute of UAMS and co-sponsored by NCBO)
March 2013
Second CTSO-AG call held
History (continued)
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Defining subject matter of the AG
Ontology in support of CTSA evaluation
Identifying and cataloging projects, software,research studies, etc. that use ontologies and theontologies they employ
Generating a tutorial on ontology targeted atjunior translational science investigators
Current Activities
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Are we interested in any type of controlled
vocabulary, thesaurus, taxonomy,
classification, etc.?
If not, what are the distinctions and why do
they matter?
White paper is currently on v6 and very close
to distribution to entire CTSO-AG
Lead: Mathias Brochhausen
Definition Activity
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Collaboration with evaluation KFC
Representing key metrics for interoperability ofevaluation data
Has links to CTSAConnect project to deliverinvestigator data (e.g., grants, pubs) data into theprocess
Two-page proposal distributed for feedback, with
ultimate goal of obtaining buy in from leadershipof Evaluation KFC
Lead: Dagobert Soergel
Evaluation Activity
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If we are going to understand how ontologies
enable translational science, then we need to
track their use and associated outcomes
Setting up Wiki site
Made initial decisions for organization of site
Lead: William Hogan
Catalog Activity
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Initial goal is deck of ~60 PowerPoint slides
Currently collecting folks existing tutorials,slides, videos, Wikis, etc.
Leads: He, Brochhausen, Soergel, Hogan
Tutorial Activity
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Google grouphttp://groups.google.com/group/ctsa-ontology
C4 sitehttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-ag
CTSO Workshops
First:http://www.bioontology.org/wiki/index.php/Clinical_and_Translational_Science_Ontology_Workshop
Second:http://ncorwiki.buffalo.edu/index.php/CTSA_Ontology_Workshop
Where to Find Stuff
http://groups.google.com/group/ctsa-ontologymailto:[email protected]://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-agmailto:[email protected]://www.bioontology.org/wiki/index.php/Clinical_and_Translational_Science_Ontology_Workshophttp://www.bioontology.org/wiki/index.php/Clinical_and_Translational_Science_Ontology_Workshophttp://www.bioontology.org/wiki/index.php/Clinical_and_Translational_Science_Ontology_Workshophttp://ncorwiki.buffalo.edu/index.php/CTSA_Ontology_Workshophttp://ncorwiki.buffalo.edu/index.php/CTSA_Ontology_Workshophttp://ncorwiki.buffalo.edu/index.php/CTSA_Ontology_Workshophttp://ncorwiki.buffalo.edu/index.php/CTSA_Ontology_Workshophttp://ncorwiki.buffalo.edu/index.php/CTSA_Ontology_Workshophttp://ncorwiki.buffalo.edu/index.php/CTSA_Ontology_Workshophttp://www.bioontology.org/wiki/index.php/Clinical_and_Translational_Science_Ontology_Workshophttp://www.bioontology.org/wiki/index.php/Clinical_and_Translational_Science_Ontology_Workshophttp://www.bioontology.org/wiki/index.php/Clinical_and_Translational_Science_Ontology_Workshopmailto:[email protected]://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-agmailto:[email protected]:[email protected]:[email protected]://groups.google.com/group/ctsa-ontologyhttp://groups.google.com/group/ctsa-ontologyhttp://groups.google.com/group/ctsa-ontology -
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Elevator pitch and operations documents
https://groups.google.com/forum/?fromgroups=#!t
opic/ctsa-ontology/BysA64zEKzc
Dropbox for tutorial effort (send request to
join to Hogan)
Where to Find (continued)
https://groups.google.com/forum/?fromgroups=https://groups.google.com/forum/?fromgroups=https://groups.google.com/forum/?fromgroups=https://groups.google.com/forum/?fromgroups=https://groups.google.com/forum/?fromgroups=https://groups.google.com/forum/?fromgroups=https://groups.google.com/forum/?fromgroups=https://groups.google.com/forum/?fromgroups= -
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Email [email protected] with: The email address you want to subscribe
Whether you are with member institution of CTSAConsortium and signed up to IKFC
Whether email address above is the one subscribed toIKFC
Join monthly calls (details emailed to both GoogleGroup and C4 listservs) Second Tuesday of the month at 2p ET
Next one is Tuesday, April 9 at 2p ET
Engage one of the current activities and drive itforward!
How to Participate in CTSO-AG
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Those instrumental to formation of group:Richard Scheuermann Barry Smith
Warren Kibbe Lindsay Cowell
Melissa Haendel Jesse Tennenbaum
Mathias Brochhausen Dagobert Soergel
JENNIFER BUFFORD!
And the remainder of the 37 participants of the firstWorkshop who self-identified as being interested inparticipating
IKFC Operations Committee for their valuablecriticisms, suggestions, recommendations, etc.
Award UL1TR000039 from NCATS
Acknowledgements