th April 2018 Feed Safety for Food Safety® - biochem.net Combination of a bacillus-based probiotic...

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Combinaon of a bacillus-based probioc and yeast- based prebioc improves fecal consistency and reduces individual anbioc treatment in early weaned piglets 17 th BOKU-Symposium, Vienna 12 th April 2018 Introducon Weaning is considered as one of the most significant events in the life of pigs accompanied by a high incidence of intesnal disturbances and diarrhea and finally by suppressed growth performance (Pluske et al., 1997). Aim of the trial was, to invesgate the effect of a combinaon of a defined probioc and a yeast-based prebioc on intesnal health (fecal score) and zootechnical performance in early weaned piglets. Material and Methods Early weaned piglets (DanBred x Piètrain, + ), weaned at 21 days of age and 5.66 ± 0.12 kg body weight 2 groups (n=4, 45 piglets per repetition) Control: without any pro-/prebiotic Treatment with a combinaon of a bacillus-based probioc (Bacillus sublis + B. licheniformis) and yeast-based prebioc (Triple P® 1000, Biochem Zusatzstoffe GmbH, Lohne) Day 1 -20 post weaning: 2 g/kg Triple P® (d1-5 blended 50:50 with creep feed) Day 21 -42 post weaning: 1 g/kg Triple P® In case of diarrhea diagnosis: individual treatment with anbioc (Enro-Sleecol® 50mg (Enrofloxacin), Albrecht, Germany) fecal score (1 - liquid diarrhea, 2 - pasty, 3 - formed feces, 4 - well-formed feces, 5 - hard and dry feces), medical treatments, mortality, body weight, feed intake Results Triple P® improved fecal consistency in critical period (day 1-14) after weaning (Fig. 1). Piglets from Triple P®-group recovered much earlier from slightly reduced fecal scores (<4) after weaning. At day 7 aſter weaning Triple P®-fed piglets showed normal fecal scores of 4, whereby fecal scores from control piglets were reduced unl day 15. No stascal difference was observed in zootechnical performance (Fig. 2), however piglets from Triple P®-group had an increased daily weight gain by +4.7% and an enhanced daily feed intake by +4.3% (Fig. 2). Piglets from control group weighed 8.37 ± 0.67 kg at day 20 and 23.43 ± 1.72 kg at day 42. Triple P®-group weighed 8.68 ± 0.62 kg at day 20 and 24.33 ± 1.60 kg at day 42. Keimer, B. 1 , Schulte, A. 1 1 R&D Department, Biochem Zusatzstoffe Handels- und Produkonsges. mbH, 49393 Lohne Conclusion The symbioc Triple P® has been shown to improve fecal scores and to reduce anbioc treatments in early weaned piglets. Therefore, Triple P® has a high potenal to be part of alternave concepts in mes of increasing demands for anbioc- and ZnO- free strategies. It should be considered, that pro- and prebiocs are more potent to prevent intesnal disturbances. Triple P® before and aſter weaning may allow even beer effects. Figure 1: Effect of dietary supplementaon of Triple P® on fecal consistency, *P < 0.1; **P < 0.05. Feed Safety for Food Safety® Figure 2: Effect of dietary supplementaon of Triple P® on individual anbioc treatment from d 1-14 aſter weaning and mortality rate. Figure 3: Effects of dietary supplementaon of Triple P® on average daily weight gain (ADWG) and average daily feed intake (ADFI) during total period (d 1 -42) of the experiment. 0 5 10 15 20 25 30 35 40 1 2 3 An�bio�c treatment [%] An�bio�c treatment Mortality Mortality [%] 0 Control Triple P® 34 25 2.2 1.6 0 100 200 300 400 500 600 700 g per piglet/day ADWG d 1-42 ADFI d 1-42 414 433 562 586 +4.7% +4.3% Control Triple P® 1 2 3 4 5 Fecal score Control Triple P® Day a�er weaning 1 2 3 4 5 6 7 8-14 15-42 * * **

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Page 1: th April 2018 Feed Safety for Food Safety® - biochem.net Combination of a bacillus-based probiotic and yeast-based prebiotic improves fecal consistency and reduces individual antibiotic

Combination of a bacillus-based probiotic and yeast-based prebiotic improves fecal consistency and reduces individual antibiotic treatment in early weaned piglets

17th BOKU-Symposium,Vienna12th April 2018

Introduction• Weaning is considered as one of the most significant

events in the life of pigs accompanied by a high incidence of intestinal disturbances and diarrhea and finally by suppressed growth performance (Pluske et al., 1997).

• Aim of the trial was, to investigate the effect of a combination of a defined probiotic and a yeast-based prebiotic on intestinal health (fecal score) and zootechnical performance in early weaned piglets.

Material and Methods• Early weaned piglets (DanBred x Piètrain, ♂ + ♀), weaned at

21 days of age and 5.66 ± 0.12 kg body weight• 2 groups (n=4, 45 piglets per repetition)• Control: without any pro-/prebiotic• Treatment with a combination of a bacillus-based probiotic

(Bacillus subtilis + B. licheniformis) and yeast-based prebiotic (Triple P® 1000, Biochem Zusatzstoffe GmbH, Lohne)

• Day 1 -20 post weaning: 2 g/kg Triple P® (d1-5 blended 50:50 with creep feed)

• Day 21 -42 post weaning: 1 g/kg Triple P®• In case of diarrhea diagnosis: individual treatment with

antibiotic (Enro-Sleecol® 50mg (Enrofloxacin), Albrecht, Germany)

• fecal score (1 - liquid diarrhea, 2 - pasty, 3 - formed feces, 4 - well-formed feces, 5 - hard and dry feces), medical treatments, mortality, body weight, feed intake

Results→ Triple P® improved fecal consistency in critical period (day 1-14) after weaning (Fig. 1). → Piglets from Triple P®-group recovered much earlier from slightly reduced fecal scores (<4) after weaning.

→ At day 7 after weaning Triple P®-fed piglets showed normal fecal scores of 4, whereby fecal scores from control piglets were reduced until day 15.

→ No statistical difference was observed in zootechnical performance (Fig. 2), however piglets from Triple P®-group had an increased daily weight gain by +4.7% and an enhanced daily feed intake by +4.3% (Fig. 2).

→ Piglets from control group weighed 8.37 ± 0.67 kg at day 20 and 23.43 ± 1.72 kg at day 42. Triple P®-group weighed 8.68 ± 0.62 kg at day 20 and 24.33 ± 1.60 kg at day 42.

Keimer, B.1, Schulte, A.1

1 R&D Department, Biochem Zusatzstoffe Handels- und Produktionsges. mbH, 49393 Lohne

ConclusionThe symbiotic Triple P® has been shown to improve fecal scores and to reduce antibiotic treatments in early weaned piglets. Therefore, Triple P® has a high potential to be part of alternative concepts in times of increasing demands for antibiotic- and ZnO-free strategies. It should be considered, that pro- and prebiotics are more potent to prevent intestinal disturbances. Triple P® before and after weaning may allow even better effects.

Figure 1: Effect of dietary supplementation of Triple P® on fecal consistency, *P < 0.1; **P < 0.05.

Feed Safety for Food Safety®

Figure 2: Effect of dietary supplementation of Triple P® on individual antibiotic treatment from d 1-14 after weaning and mortality rate.

Figure 3: Effects of dietary supplementation of Triple P® on average daily weight gain (ADWG) and average daily feed intake (ADFI) during total period (d 1 -42) of the experiment.

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