Technology and Best Practices for Recruitment
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Transcript of Technology and Best Practices for Recruitment
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Technology & Best Practices for Recruitment
Nariman A. Nasser, Director UCSF Participant Recruitment Service
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SOCIAL MEDIA & EMERGING TECHNOLOGIES
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What is Social Media? The use of web-based and mobile technologies to turn
communication into interactive dialogue
1. Collaborative projects
2. Blogs and Microblogs
3. Content communities
4. Social networking sites
5. Virtual game worlds
6. Virtual communities
Kaplan and Haenlein, Business Horizons, 2010
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The Power of Social Media
• Recommendations by family/peers are more influential
• Reach wide number of motivated/interested individuals in a short time
• Encourages empowerment and proactive behavior
• Able to communicate in real-time
• Ideal for AE reporting and post-marketing surveillance (FDA/NIH Safety Reporting Portal)
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Clinical Trials Networking Sites
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The Unwieldy Power of Social Media
• Unless social media is used for real-time communication it is no different than a traditional media advertisement
• Real-time communication in the context of clinical trials recruiting must be carefully moderated
• FDA regulations are not conducive to brevity, no guidance to date (Novartis widget incident failed to communicate risk information, implies superiority)
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Emerging Technologies
• Electronic personal health records (Google Health, HealthVault)
• Research volunteer registries (Volunteers for Health, ResearchMatch.org, TrialX)
• Electronic communication methods (text messaging, emailing health professionals, online screening tools)
• Telemedicine
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TEXT MESSAGING FOR RECRUITMENT
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Mobile phones are changing the way people interact with the world around them MOBILE FACTS POTENTIAL
5.5 billion Global Subscribers* Mobile devices are now practically ubiquitous
Penetration rates >80%* in most countries (US = 285M subs or 91%)
Worldwide Tool - large metropolitan areas to rural developing world
Mobile Phone within arms reach of average users for 19 hours per day †
Mobile phone users read messages within
15 minutes of receipt†
Mobile is the most effective and natural way to maintain contact with clinical trial
participants
Mobile communications are immediate, verifiable and actionable
Mobile phone users respond within 60 minutes†
Average mobile phone users send/receive 4x as many text messages as voice calls†
Clinical trial participants will use their mobile phones to provide information
to clinical sites
•* Merrill Lynch Q3-2009/CTIA 2010 † Nielsen Q4-2008/10 ‡ Luth Research 2009.
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Teens text, and so do their parents
parents text twice as much as they call
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SMS Recruitment – Data points
70% prefer to inquire via text message
90% response rate = highly engaged
Significant ROI 3 months traditional method followed by 3 months with text messaging
• Cost per Response decreased by 15% • Cost per Referral decreased by 32% • ROI > 650%
OmniScience Mobile
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0%20%40%60%80%
100%
Day
1
Day
2
Day
3
CallCenterTextMessaging
60% of those who use SMS are referred “I contacted a subject who responded by text message and it went great! She is scheduled for a visit within the week.” study coordinator within 2 hours of receipt
“…it was very easy to maneuver.” anonymous patient
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SMS for Recruitment
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How NOT to Run an SMS Campaign
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MOBILE APPS FOR RECRUITMENT & RETENTION
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Mobile Apps for Recruitment Have Limitations
•Limited Reach – Smartphones only – Used by only 36% of US mobile subscribers / 14% international subscribers
•Expensive – software app must support all major platforms: iOS, Android, Windows, RIM,
Nokia – significant cost for development & maintenance
•Highly Inefficient as Direct Response option – Promotional materials driving traffic to an app there are too many steps:
1. Go to your phone’s app store 2. Find our app 3. Download it 4. Figure out where the app is on your phone 5. Click on the app to learn more about this study
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Reference Apps Don’t Really Generate Referrals Clinical Trials Mobile app
Who will take the time to find this app and use it to search for clinical trials?
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QR CODES
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The Good and the Bad
• Inexpensive
•Only work for smartphone users
• Few have incorporated QR scanning into behavior
• Execution is tricky – You can’t remember a QR code and ‘text’ it later – Challenging for outdoor advertising
21
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The Ugly
• No cell signal in NYC subway
• Creative design blocks code
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VOLUNTEER REGISTRIES & RECRUITMENT PROTOCOLS
Other Technologies
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San Francisco General Hospital Recruitment Pilot
• Investigators want to extend their reach
• 1 year pilot program for 10 studies – 24/7 staffed phone line – Weekly craigslist posting – Outgoing calls to follow-up as needed
• Outcomes – 692 volunteers (validated unique) – 25% contacted for screening visits – BMI was most beneficial data field for search criteria
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Airway Clinical Research Center Asthma Recruitment Database
• Local disease-specific database
• Used as recruitment protocol/registry
– Characterize asthma severity
– Recruit for current studies real-time
– Register for contact regarding future studies – already prequalified
•UCSF Airway Clinical Research Center (ACRC)
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Recruitment Trends by County
San Francisco 52%
Alameda 16%
San Mateo 11%
Contra Costa 7%
Santa Clara 4%
Marin 3%
Sonoma 2%
Solano 1%
•UCSF Airway Clinical Research Center (ACRC)
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BEST PRACTICES
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Performing Initial Analyses
Study Design Site-specific protocols for study-specific and SOC
procedures Placebo arms, excessive inclusion/exclusion criteria
Site-specific Staff resources Location(s): accessibility, interoperability, features /
disadvantages
Competing Trials
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Planning & Budgeting
Screen Failure Rate
Budget for the unexpected Design revisions Increased production & shipping costs over time Protocol revisions impacting recruiting
methods/materials
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Implementing the Plan
Staged approach
Multiple simultaneous advertising efforts
Plan on changing your plan – analyze relatively often
Communication Plan Sponsor/Site Staff Primary contacts Secondary contacts
Identify screening appointment schedule workflow, tools and conflicts
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Ensuring High-Quality Participants
Start by casting a wide net Think about a wide number of things or people when choosing the
thing or person you want*
Don’t skip the prescreening step
Ask the right questions at the right stage of the recruitment process
*Idioms by The Free Dictionary
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Monitoring Progress
Set realistic expectations up front
Identify benchmarks for success/failure
Simple tracking tools go a long way
Receiving logs & reports is not enough – they have to mean something and be actionable
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THE UCSF PARTICIPANT RECRUITMENT SERVICE
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Create a centralized service to facilitate the enrollment of research participants into UCSF clinical studies
Assume a large part of the burden of recruitment efforts
Provide expertise in recruitment materials development
Ensure materials meet regulatory guidelines and requirements
Offer an economy of scale for many recruitment activities
Use established vendor relationships
Increase the volume of high quality volunteers
Facilitate a wider catchment and more robust networks
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Recruitment Analysis and Planning
Robust recruitment plan Analysis of recruitment landscape
Protocol complexities, procedures, SOC Competing studies Geographic/demographic population Marketing & Outreach methodologies
Suggested strategies Timelines Budgets for suggested strategies
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Cohort ID and Direct Mail
Identify cohorts from inpatient medical records (UCare and ThREDS) ICD-9 codes Demographics
CHR modification
Coordinate data extract services from ARS
Print and mail direct mail letters to cohort
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Recruitment Materials Toolkit
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Future Services/Resources
Recruitment Plan Implementation Centralized call center, text messaging, online
screeners Marketing & outreach Referral networks
Searchable database of actively recruiting studies – matching
Real-time recruitment from EMR
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THANK YOU