Surgical Therapy for Vitiligo - American Academy … Therapy for Vitiligo February 17th, 2018...
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Surgical Therapy for Vitiligo February 17 th , 2018 Iltefat Hamzavi, MD Senior Staff Physician Henry Ford Hospital, Detroit, Michigan Hamzavi Dermatology-SE Michigan Type of Surgery Pros Cons MKTP Treatment of large, irregular areas 84% repigmentation Requires special training, personnel and equipment Cultured Melanocyte Transplantation Treatment of large, irregular areas 75-84% repigmentation Requires increased time for culture, special training, personnel and equipment, IRB Approval (risk of melanoma) Punch Grafting Readily available, does not require additional equipment of training 75-84% repigmentation Poor cosmetic effect (cobblestoning), typically needs adjuvant UV treatment Blister Grafting Readily available Good colormatching/ cosmetic result 80-91% repigmentation Time consuming (up to 5 hours for blister formation alone) Painful
Transcript of Surgical Therapy for Vitiligo - American Academy … Therapy for Vitiligo February 17th, 2018...
Surgical Therapy for Vitiligo February 17th, 2018 Iltefat Hamzavi, MD Senior Staff Physician Henry Ford Hospital, Detroit, Michigan Hamzavi Dermatology-SE Michigan
Type of Surgery Pros Cons
MKTP Treatment of large,
irregular areas 84% repigmentation
Requires special training, personnel and
equipment
Cultured Melanocyte Transplantation
Treatment of large, irregular areas
75-84% repigmentation
Requires increased time for culture, special training, personnel and
equipment, IRB Approval (risk of
melanoma)
Punch Grafting
Readily available, does not require additional equipment of training
75-84% repigmentation
Poor cosmetic effect (cobblestoning), typically needs
adjuvant UV treatment
Blister Grafting
Readily available Good colormatching/
cosmetic result 80-91% repigmentation
Time consuming (up to 5 hours for blister formation alone)
Painful
Split Thickness Grafting
Treat large areas87% repigmentation
Milia formation at recipient site (poor
cosmetic effect) Before After MKTP
References: Narumol Silpa-archa, M.D.; James Griffith, MD.; Richard Huggins, MD.; Marsha Henderson, MD.; Holly Kerr, MD.; Gordon Jacobsen, MS; Sanjeev Mulekar, MD.; Henry W Lim, MD.; Iltefat H Hamzavi, MD. Autologous Non-cultured Melanocyte-Keratinocyte Transplantation Procedure (MKTP) in Vitiligo and Other Leukodermas: A Long-Term Follow-up . Journal of the Am Acad Derm. In press 2017. Ghia D, Mulekar SV Hamzavi IH. Surgical Management of Vitiligo. In: Handbook of Vitligo. JP Medical Press; 2016.
