Surgical techniques for sciatica due to herniated disc, a systematic review. Jacobs WC, Arts MP, van...
Transcript of Surgical techniques for sciatica due to herniated disc, a systematic review. Jacobs WC, Arts MP, van...
96 Journal Reports / The Spine Journal 13 (2013) 95–97
PMID: 22878599 [PubMed - indexed for MEDLINE. Available at: http://
www.ncbi.nlm.nih.gov/pubmed/22878599].
Reprinted with permission from: Radcliff K, Hwang R, Hilibrand A,
et al. The effect of iliac crest autograft on the outcome of fusion in
the setting of degenerative spondylolisthesis: a subgroup analysis of
the Spine Patient Outcomes Research Trial (SPORT). J Bone Joint Surg
Am 2012;94(18):1685–92. Available at: http://jbjs.org/article.aspx?
articleid=1262703.
http://dx.doi.org/10.1016/j.spinee.2013.01.007
Comparison between patient and surgeon perception of outcomes of
operations for degenerative spine disease: a prospective blinded
database study. Thaci B, Roitberg BZ, Lam SK, Brown FD, Shen J.
Neurosurgery 2012;71(2):E555.
INTRODUCTION: Patient filled questionnaires, such as Oswestry Dis-
ability Index (ODI) or Neck Disability Index (NDI) have become the main-
stay in evaluation of treatment outcomes in degenerative spine disease
(DSD), replacing result reporting by surgeons. In this study we set to com-
pare patients’ and surgeons’ assessment of spine treatment outcome in
a prospective blinded patient-driven spine surgery outcomes registry.
METHODS: Patients referred to the neurosurgery clinic between 9/8/09
and 11/1/2011 filled out surveys at baseline, at recruitment preoperatively,
and at 3 and 6 months postoperatively. The surgeons were blinded to the
survey content. Pain was rated on a Visual Analog Scale (VAS) from
0–10, while NDI was scored for cervical spine patients and ODI for lumbar
patients. At 3 and 6 months postoperatively, outcome was rated indepen-
dently by patients and surgeons on a 7-point Likert-type scale
RESULTS: 337 patients prospectively enrolled in the database with inten-
tion to treat; 134 (40%) had cervical spine disease, 195 (58%) had lumbar
spine disease and 8 patients (2%) had both. 109 (32%) had outcome ratings
from both the patient and the surgeon in corresponding time frames. We
found that surgeons’ and patients’ ratings correlated strongly (Spearman
rho50.4, ***p!.0001); with 44.6% identical and 86.7% within 61 grade
of each other. Patient rating correlated better with most recent NDI/ODI
and pain score than with the incremental change from the baseline. In
a multivariate analysis, the age of the patient and identity of the surgeon
were the only variables that had significant impact on the ratings’ discrep-
ancy (*p5.02 and *p5.04, respectively).
CONCLUSIONS: We show that patients’ and surgeons’ global outcome
ratings for spinal disease correlate highly with each other. Also, patients’
ratings correlate better with their most recent functional scores rather than
the incremental change from their baseline.
Reprinted with permission from: Thaci B, Roitberg BZ, Lam SK, Brown
FD, Shen J. 137 Comparison between patient and surgeon perception of
outcomes of operations for degenerative spine disease: a prospective
blinded database study. Neurosurgery 2012;71(2):E555.
http://dx.doi.org/10.1016/j.spinee.2013.01.008
Is cauda equina syndrome linked with obesity? Venkatesan M,
Uzoigwe CE, Perianayagam G, Braybrooke JR, Newey ML. J Bone
Joint Surg Br 2012;94(11):1551–6.
No previous studies have examined the physical characteristics of patients
with cauda equina syndrome (CES). We compared the anthropometric fea-
tures of patients who developed CES after a disc prolapse with those who
did not but who had symptoms that required elective surgery. We recorded
the age, gender, height, weight and body mass index (BMI) of 92
consecutive patients who underwent elective lumbar discectomy and 40
consecutive patients who underwent discectomy for CES. On univariate
analysis, the mean BMI of the elective discectomy cohort (26.5 kg/m2
(16.6 to 41.7) was very similar to that of the age-matched national mean
(27.6 kg/m2, p51.0). However, the mean BMI of the CES cohort (31.1
kg/m2 (21.0 to 54.9)) was significantly higher than both that of the elective
group (p!.001) and the age-matched national mean (p!.001). A similar
pattern was seen with the weight of the groups. Multivariate logistic re-
gression analysis was performed, adjusted for age, gender, height, weight
and BMI. Increasing BMI and weight were strongly associated with an in-
creased risk of CES (odds ratio (OR) 1.17, p!.001; and OR 1.06, p!.001,
respectively). However, increasing height was linked with a reduced risk of
CES (OR 0.9, p!.01). The odds of developing CES were 3.7 times higher
(95% confidence interval (CI) 1.2 to 7.8, p5.016) in the overweight and
obese (as defined by the World Health Organization: BMI$25 kg/m2) than
in those of ideal weight. Those with very large discs (obstructingO75% of
the spinal canal) had a larger BMI than those with small discs (obstruct-
ing!25% of the canal; p!.01). We therefore conclude that increasing
BMI is associated with CES.
PMID: 23109638 [PubMed - in process. Available at: http://www.ncbi.
nlm.nih.gov/pubmed/23109638].
Reproduced from: Venkatesan M, Uzoigwe CE, Perianayagam G, Bray-
brooke JR, Newey ML. Is cauda equina syndrome linked with obesity?
J Bone Joint Surg Br 2012;94(11):1551–6, with permission and copy-
right � of the British Editorial Society of Bone and Joint Surgery.
http://dx.doi.org/10.1016/j.spinee.2013.01.009
Surgical techniques for sciatica due to herniated disc, a systematic
review. Jacobs WC, Arts MP, van Tulder MW, et al. Eur Spine J
2012;21(11):2232–51. Epub 2012 Jul 20.
INTRODUCTION: Disc herniation with sciatica accounts for five percent
of low-back disorders but is one of the most common reasons for spine sur-
gery. The goal of this study was to update the Cochrane review on the ef-
fect of surgical techniques for sciatica due to disc herniation, which was
last updated in 2007.
MATERIALS AND METHODS: In April 2011, we conducted a compre-
hensive search in CENTRAL, MEDLINE, EMBASE, CINAHL, PEDRO,
ICL, and trial registries. We also checked the reference lists and citation
tracking results of each retrieved article. Only randomized controlled trials
(RCT) of the surgical management of sciatica due to disc herniation were
included. Comparisons including chemonucleolysis and prevention of scar
tissue or comparisons against conservative treatment were excluded. Two
review authors independently selected studies, assessed risk of bias of the
studies and extracted data. Quality of evidence was graded according to the
GRADE approach.
RESULTS: Seven studies from the original Cochrane review were in-
cluded and nine additional studies were found. In total, 16 studies were in-
cluded, of which four had a low risk of bias. Studies showed that
microscopic discectomy results in a significantly, but not clinically relevant
longer operation time of 12 min (95% CI 2–22) and shorter incision of 24
mm (95% CI 7–40) compared with open discectomy, but did not find any
clinically relevant superiority of either technique on clinical results. There
were conflicting results regarding the comparison of tubular discectomy
versus microscopic discectomy for back pain and surgical duration.
CONCLUSIONS: Due to the limited amount and quality of evidence, no
firm conclusions on effectiveness of the current surgical techniques being
open discectomy, microscopic discectomy, and tubular discectomy com-
pared with each other can be drawn. Those differences in leg or back pain
scores, operation time, and incision length that were found are clinically
insignificant. Large, high-quality studies are needed, which examine not
only effectiveness but cost-effectiveness as well.
97Journal Reports / The Spine Journal 13 (2013) 95–97
PMID: 22814567 [PubMed - in process. Available at: http://www.ncbi.
nlm.nih.gov/pubmed/22814567].
Reprinted with permission from: Jacobs WC, Arts MP, van Tulder MW,
et al. Surgical techniques for sciatica due to herniated disc, a systematic
review. Eur Spine J 2012;21(11):2232–51. Epub 2012 Jul 20. Available
at: http://link.springer.com/article/10.1007/s00586-012-2422-9.
http://dx.doi.org/10.1016/j.spinee.2013.01.010
The role of fusion in the management of burst fractures of the
thoracolumbar spine treated by short segment pedicle screw
fixation: a prospective randomised trial. Jindal N, Sankhala SS,
Bachhal V. J Bone Joint Surg Br 2012;94(8):1101–6.
The purpose of this study was to determine whether patients with a burst
fracture of the thoracolumbar spine treated by short segment pedicle screw
fixation fared better clinically and radiologically if the affected segment
was fused at the same time. A total of 50 patients were enrolled in a pro-
spective study and assigned to one of two groups. After the exclusion of
three patients, there were 23 patients in the fusion group and 24 in the
non-fusion group. Follow-up was at a mean of 23.9 months (18 to 30).
Functional outcome was evaluated using the Greenough Low Back Out-
come Score. Neurological function was graded using the American Spinal
Injury Association Impairment Scale. Radiological outcome was assessed
on the basis of the angle of kyphosis. Peri-operative blood transfusion re-
quirements and duration of surgery were significantly higher in the fusion
group (p5.029 and p!.001, respectively). There were no clinical or radio-
logical differences in outcome between the groups (all outcomes pO.05).
The results of this study suggest that adjunctive fusion is unnecessary
when managing patients with a burst fracture of the thoracolumbar spine
with short segment pedicle screw fixation.
PMID: 22844053 [PubMed - indexed for MEDLINE. Available at: http://
www.ncbi.nlm.nih.gov/pubmed/22844053].
Reproduced from: Jindal N, Sankhala SS, Bachhal V. The role of fusion in
the management of burst fractures of the thoracolumbar spine treated by
short segment pedicle screw fixation: a prospective randomised trial.
J Bone Joint Surg Br 2012;94(8):1101–6, with permission and copyright �of the British Editorial Society of Bone and Joint Surgery.
http://dx.doi.org/10.1016/j.spinee.2013.01.011
The relationship between pain and depressive symptoms after
lumbar spine surgery. Skolasky RL, Riley LH 3rd, Maggard AM,
Wegener ST. Pain 2012;153(10):2092–6. Epub 2012 Aug 3.
Although depressive symptoms are common among those living with back
pain, there is limited information on the relationship between postsurgical
pain reduction and changes in depressive symptoms. The objective of this
prospective cohort study was to examine the change in pain and depressive
symptoms and to characterize the relationship between pain and depressive
symptoms after lumbar spine surgery. We assessed 260 individuals undergo-
ing lumbar spine surgery preoperatively and postoperatively (3 and 6
months) using a pain intensity numeric rating scale and the Patient Health
Questionnaire depression scale. The relationship between change in pain
(a 2-point decrease or 30%reduction from the preoperative level) and depres-
sive symptoms was examined using standard regression methods. Preopera-
tively, the mean pain intensity was 5.2 (SD 2.4) points, and the mean
depressive symptom score was 5.03 (SD 2.44) points. At 3 months, individ-
uals who experienced a reduction in pain (63%)were nomore likely to expe-
rience a reduction in depressive symptoms (odds ratio 1.07, 95% confidence
interval [CI] 0.58 to 1.98) than individuals who experienced no change from
preoperative pain (34%).However, at 6months, individualswho experienced
a reduction in pain (63%) were nearly twice as likely to experience a reduc-
tion in depressive symptoms (odds ratio 1.93, 95% CI 1.15 to 3.25) as those
who experienced no change or an increase in pain (31%).We found thatmost
individuals experienced clinically important reductions in pain after surgery.
We concluded that thosewhosepain levelwas reduced at 6monthsweremore
likely to experience a reduction in depressive symptoms.
Copyright � 2012 International Association for the Study of Pain. Pub-
lished by Elsevier B.V. All rights reserved.
PMID: 22867701 [PubMed - in process. Available at: http://www.ncbi.
nlm.nih.gov/pubmed/22867701].
Reprinted from: Skolasky RL, Riley LH 3rd, Maggard AM, Wegener ST.
The relationship between pain and depressive symptoms after lumbar spine
surgery. Pain 2012;153(10):2092–6. Epub 2012 Aug 3. This abstract has
been reproduced with permission of the International Association for the
Study of Pain� (IASP�). The abstract may not be reproduced for any
other purpose without permission.
http://dx.doi.org/10.1016/j.spinee.2013.01.012
The sharp slowdown in growth of medical imaging: an early analysis
suggests combination of policies was the cause. Lee DW, Levy F.
Health Aff (Millwood) 2012;31(8):1876–84. Epub 2012 Jul 25.
The growth in the use of advanced imaging for Medicare beneficiaries decel-
erated in 2006 and 2007, ending a decade of growth that had exceeded 6 per-
cent annually. The slowdown raises three questions. Did the slowdown in
growth of imaging underMedicare persist and extend to the non-Medicare in-
sured?What factors caused the slowdown?Was the slowdowngood or bad for
patients?Using claims file data and interviewswith health care professionals,
we found that the growth of imaging use among both Medicare beneficiaries
and the non-Medicare insured slowed to 1–3 percent per year through 2009.
One by-product of this deceleration in imaging growth was a weaker market
for radiologists, who until recently could demand top salaries. The expansion
of prior authorization, increased cost sharing, and other policies appear to
have contributed to the slowdown. A meaningful fraction of the reduction
in use involved imaging studies previously identified as having unproven
medical value. What has occurred in the imaging field suggests incentive-
based cost control measures can be a useful complement to comparative ef-
fectiveness research when a procedure’s ultimate clinical benefit is uncertain.
PMID: 22842655 [PubMed - indexed for MEDLINE. Available at: http://
www.ncbi.nlm.nih.gov/pubmed/22842655].
Copyrighted and published by Project HOPE/Health Affairs as: Lee DW,
Levy F. The sharp slowdown in growth of medical imaging: an early anal-
ysis suggests combination of policies was the cause. Health Aff (Mill-
wood) 2012;31(8):1876–84. Epub 2012 Jul 25.
http://dx.doi.org/10.1016/j.spinee.2013.01.013