SURFACE FREEZING FOR DEEP PAIN

1
288 " XBD=175 XHG=91 YBD=215 YHG=184>well " XBD=234 XHG=193 YBD=215 YHG=194>as " XBD=350 XHG=251 YBD=215 YHG=185>from " XBD=516 XHG=369 YBD=215 YHG=180>clinical " XBD=753 XHG=534 YBD=224 YHG=184>experience " XBD=800 XHG=769 YBD=215 YHG=184>it " XBD=848 XHG=816 YBD=215 YHG=184>is " XBD=946 XHG=867 YBD=215 YHG=185>safe " XBD=1005 XHG=964 YBD=215 YHG=186>to " XBD=1092 XHG=1025 YBD=224 YHG=194>say " XBD=1198 XHG=1111 YBD=215 YHG=185>that " XBD=1284 XHG=1216 YBD=216 YHG=185>the " XBD=304 XHG=92 YBD=267 YHG=227>possession " XBD=358 XHG=319 YBD=259 YHG=228>of " XBD=422 XHG=372 YBD=259 YHG=238>an " XBD=545 XHG=437 YBD=259 YHG=237>arcus " XBD=685 XHG=561 YBD=259 YHG=227>senilis " XBD=790 XHG=700 YBD=259 YHG=228>does " XBD=872 XHG=804 YBD=258 YHG=228>not " XBD=998 XHG=888 YBD=259 YHG=238>mean " XBD=1063 XHG=1013 YBD=259 YHG=228>its " XBD=1202 XHG=1078 YBD=259 YHG=237>owner " XBD=1284 XHG=1215 YBD=259 YHG=228>has " XBD=266 XHG=91 YBD=303 YHG=272>vascular " XBD=438 XHG=284 YBD=304 YHG=272>disease. VENOUS OBSTRUCTION IN VOLKMANN’S CONTRACTURE " XBD=280 XHG=147 YBD=475 YHG=445>THOSE " XBD=386 XHG=302 YBD=475 YHG=445>who " XBD=507 XHG=408 YBD=476 YHG=445>have " XBD=616 XHG=528 YBD=475 YHG=445>held " XBD=725 XHG=637 YBD=475 YHG=445>that " XBD=890 XHG=746 YBD=475 YHG=454>venous " XBD=1149 XHG=912 YBD=476 YHG=445>obstruction " XBD=1201 XHG=1170 YBD=476 YHG=446>is " XBD=1288 XHG=1222 YBD=476 YHG=446>the " XBD=197 XHG=97 YBD=519 YHG=490>most " XBD=428 XHG=217 YBD=528 YHG=488>important " XBD=571 XHG=447 YBD=520 YHG=489>factor " XBD=630 XHG=590 YBD=519 YHG=489>in " XBD=716 XHG=650 YBD=519 YHG=489>the " XBD=963 XHG=735 YBD=528 YHG=488>production " XBD=1021 XHG=984 YBD=519 YHG=489>of " XBD=1289 XHG=1042 YBD=521 YHG=490>Volkmann’s " XBD=285 XHG=96 YBD=563 YHG=532>ischaemic " XBD=546 XHG=306 YBD=564 YHG=535>contracture " XBD=666 XHG=567 YBD=563 YHG=533>have " XBD=804 XHG=687 YBD=563 YHG=533>based " XBD=924 XHG=825 YBD=563 YHG=532>their " XBD=1058 XHG=944 YBD=564 YHG=532>belief " XBD=1219 XHG=1077 YBD=574 YHG=534>largely " XBD=1327 XHG=1241 YBD=564 YHG=536>on " XBD=121 XHG=98 YBD=606 YHG=585>a " XBD=334 XHG=147 YBD=616 YHG=577>supposed " XBD=498 XHG=359 YBD=616 YHG=576>special " XBD=792 XHG=521 YBD=615 YHG=576>vulnerability " XBD=856 XHG=818 YBD=606 YHG=576>of " XBD=945 XHG=880 YBD=606 YHG=576>the " XBD=1290 XHG=971 YBD=608 YHG=578>communication " XBD=269 XHG=97 YBD=651 YHG=619>between " XBD=351 XHG=285 YBD=651 YHG=620>the " XBD=581 XHG=370 YBD=659 YHG=620>superficial " XBD=675 XHG=599 YBD=650 YHG=620>and " XBD=785 XHG=693 YBD=659 YHG=620>deep " XBD=947 XHG=804 YBD=650 YHG=629>venous " XBD=1127 XHG=966 YBD=660 YHG=622>systems " XBD=1290 XHG=1145 YBD=652 YHG=621>around " XBD=165 XHG=98 YBD=695 YHG=663>the " XBD=324 XHG=194 YBD=695 YHG=664>elbow. " XBD=424 XHG=378 YBD=699 YHG=664>If, " XBD=496 XHG=455 YBD=694 YHG=673>as " XBD=594 XHG=524 YBD=694 YHG=664>has " XBD=718 XHG=622 YBD=694 YHG=664>been " XBD=846 XHG=746 YBD=699 YHG=663>held, " XBD=942 XHG=875 YBD=694 YHG=664>the " XBD=1291 XHG=972 YBD=695 YHG=665>communication " XBD=267 XHG=99 YBD=748 YHG=707>depends " XBD=344 XHG=296 YBD=738 YHG=717>on " XBD=444 XHG=374 YBD=738 YHG=717>one " XBD=583 XHG=473 YBD=738 YHG=707>small " XBD=754 XHG=611 YBD=738 YHG=717>venous " XBD=944 XHG=784 YBD=739 YHG=708>channel " XBD=1230 XHG=966 YBD=749 YHG=709>lying deeply " XBD=1291 XHG=1251 YBD=738 YHG=709>in " XBD=166 XHG=98 YBD=782 YHG=752>the " XBD=420 XHG=185 YBD=783 YHG=751>antecubital " XBD=551 XHG=438 YBD=788 YHG=752>fossa, " XBD=600 XHG=569 YBD=782 YHG=752>it " XBD=651 XHG=619 YBD=782 YHG=751>is " XBD=760 XHG=671 YBD=792 YHG=761>easy " XBD=821 XHG=779 YBD=783 YHG=754>to " XBD=1017 XHG=841 YBD=783 YHG=752>visualise " XBD=1085 XHG=1035 YBD=783 YHG=753>its " XBD=1291 XHG=1105 YBD=792 YHG=752>complete " XBD=354 XHG=99 YBD=835 YHG=795>interruption " XBD=424 XHG=372 YBD=835 YHG=796>by " XBD=508 XHG=442 YBD=826 YHG=796>the " XBD=780 XHG=528 YBD=835 YHG=796>compression " XBD=838 XHG=800 YBD=827 YHG=796>of " XBD=1007 XHG=856 YBD=828 YHG=796>swollen " XBD=1101 XHG=1025 YBD=827 YHG=797>and " XBD=1293 XHG=1119 YBD=835 YHG=796>bleeding " XBD=249 XHG=101 YBD=876 YHG=839>tissues, " XBD=360 XHG=285 YBD=870 YHG=840>and " XBD=639 XHG=392 YBD=880 YHG=840>particularly " XBD=724 XHG=672 YBD=880 YHG=840>by " XBD=779 XHG=757 YBD=871 YHG=850>a " XBD=1018 XHG=816 YBD=872 YHG=841>subfascial " XBD=1290 XHG=1050 YBD=871 YHG=841>haematoma. " XBD=150 XHG=103 YBD=914 YHG=883>In " XBD=195 XHG=173 YBD=914 YHG=893>a " XBD=330 XHG=220 YBD=915 YHG=884>series " XBD=394 XHG=355 YBD=914 YHG=884>of " XBD=559 XHG=418 YBD=915 YHG=884>careful " XBD=813 XHG=583 YBD=916 YHG=885>anatomical " XBD=979 XHG=837 YBD=916 YHG=884>studies Horwitz " XBD=1293 XHG=1188 YBD=915 YHG=884>has " XBD=389 XHG=103 YBD=960 YHG=928>demonstrated " XBD=491 XHG=425 YBD=960 YHG=929>the " XBD=737 XHG=527 YBD=961 YHG=930>variations " XBD=861 XHG=773 YBD=961 YHG=930>that " XBD=968 XHG=898 YBD=960 YHG=939>can " XBD=1117 XHG=1006 YBD=961 YHG=939>occur " XBD=1192 XHG=1152 YBD=959 YHG=929>in " XBD=1294 XHG=1228 YBD=959 YHG=928>the " XBD=443 XHG=104 YBD=1005 YHG=973>communications " XBD=660 XHG=488 YBD=1005 YHG=974>between " XBD=772 XHG=705 YBD=1005 YHG=975>the " XBD=913 XHG=819 YBD=1013 YHG=975>deep " XBD=1037 XHG=961 YBD=1004 YHG=974>and " XBD=1296 XHG=1083 YBD=1013 YHG=972>superficial " XBD=247 XHG=103 YBD=1048 YHG=1027>venous " XBD=428 XHG=266 YBD=1058 YHG=1019>systems " XBD=486 XHG=446 YBD=1049 YHG=1019>at " XBD=571 XHG=505 YBD=1049 YHG=1018>the " XBD=720 XHG=590 YBD=1053 YHG=1019>elbow. " XBD=832 XHG=774 YBD=1048 YHG=1019>He " XBD=918 XHG=848 YBD=1048 YHG=1018>has " XBD=1067 XHG=936 YBD=1049 YHG=1017>shown " XBD=1171 XHG=1084 YBD=1049 YHG=1017>that " XBD=1295 XHG=1189 YBD=1047 YHG=1017>there " XBD=168 XHG=104 YBD=1092 YHG=1071>are " XBD=293 XHG=186 YBD=1093 YHG=1062>three " XBD=468 XHG=313 YBD=1093 YHG=1062>distinct " XBD=682 XHG=489 YBD=1093 YHG=1062>collateral " XBD=806 XHG=699 YBD=1094 YHG=1062>veins " XBD=867 XHG=827 YBD=1092 YHG=1071>or " XBD=1030 XHG=887 YBD=1092 YHG=1071>venous " XBD=1237 XHG=1049 YBD=1092 YHG=1061>networks " XBD=1296 XHG=1256 YBD=1091 YHG=1061>in " XBD=278 XHG=105 YBD=1137 YHG=1106>addition " XBD=359 XHG=317 YBD=1137 YHG=1108>to " XBD=465 XHG=399 YBD=1137 YHG=1107>the " XBD=684 XHG=506 YBD=1137 YHG=1106>so-called " XBD=1044 XHG=724 YBD=1145 YHG=1105>communicating " XBD=1182 XHG=1083 YBD=1136 YHG=1105>vein. " XBD=1294 XHG=1234 YBD=1144 YHG=1105>By " XBD=288 XHG=104 YBD=1191 YHG=1150>injecting " XBD=540 XHG=308 YBD=1191 YHG=1151>radiopaque " XBD=729 XHG=562 YBD=1181 YHG=1150>medium " XBD=857 XHG=752 YBD=1192 YHG=1149>(30% " XBD=1030 XHG=883 YBD=1180 YHG=1149>sodium " XBD=1192 XHG=1052 YBD=1188 YHG=1149>iodide) " XBD=1296 XHG=1214 YBD=1180 YHG=1149>into " XBD=172 XHG=72 YBD=1226 YHG=1189>the " XBD=311 XHG=191 YBD=1235 YHG=1205>upper " XBD=536 XHG=331 YBD=1235 YHG=1195>extremity " XBD=595 XHG=556 YBD=1225 YHG=1195>of " XBD=661 XHG=618 YBD=1225 YHG=1196>10 " XBD=873 XHG=671 YBD=1230 YHG=1187>cadavers, " XBD=917 XHG=895 YBD=1224 YHG=1203>a " XBD=1048 XHG=937 YBD=1224 YHG=1194>series " XBD=1106 XHG=1069 YBD=1224 YHG=1194>of " XBD=1298 XHG=1126 YBD=1233 YHG=1193>complex " XBD=297 XHG=106 YBD=1271 YHG=1240>networks " XBD=413 XHG=335 YBD=1270 YHG=1249>was " XBD=739 XHG=453 YBD=1270 YHG=1239>demonstrated " XBD=990 XHG=777 YBD=1269 YHG=1237>additional " XBD=1069 XHG=1027 YBD=1268 YHG=1239>to " XBD=1174 XHG=1108 YBD=1268 YHG=1238>the " XBD=1299 XHG=1213 YBD=1268 YHG=1238>four " XBD=445 XHG=107 YBD=1315 YHG=1284>communications " XBD=595 XHG=471 YBD=1314 YHG=1283>which " XBD=717 XHG=620 YBD=1313 YHG=1288>were " XBD=844 XHG=743 YBD=1323 YHG=1283>large " XBD=1019 XHG=870 YBD=1322 YHG=1282>enough " XBD=1086 XHG=1046 YBD=1313 YHG=1284>to " XBD=1161 XHG=1113 YBD=1313 YHG=1282>be " XBD=1299 XHG=1188 YBD=1313 YHG=1282>made " XBD=177 XHG=110 YBD=1359 YHG=1329>out " XBD=260 XHG=208 YBD=1368 YHG=1328>by " XBD=393 XHG=291 YBD=1368 YHG=1337>gross " XBD=638 XHG=425 YBD=1358 YHG=1327>dissection. " XBD=769 XHG=690 YBD=1358 YHG=1327>The " XBD=948 XHG=800 YBD=1357 YHG=1326>sodium " XBD=1104 XHG=978 YBD=1357 YHG=1326>iodide " XBD=1299 XHG=1134 YBD=1366 YHG=1326>injected " XBD=189 XHG=107 YBD=1403 YHG=1372>into " XBD=284 XHG=214 YBD=1403 YHG=1382>one " XBD=345 XHG=306 YBD=1403 YHG=1372>of " XBD=432 XHG=366 YBD=1402 YHG=1372>the " XBD=574 XHG=453 YBD=1402 YHG=1371>radial " XBD=638 XHG=597 YBD=1401 YHG=1380>or " XBD=768 XHG=659 YBD=1402 YHG=1371>ulnar " XBD=896 XHG=790 YBD=1402 YHG=1371>veins " XBD=1107 XHG=919 YBD=1411 YHG=1372>appeared " XBD=1298 XHG=1128 YBD=1402 YHG=1371>immedi- " XBD=213 XHG=109 YBD=1456 YHG=1417>ately " XBD=276 XHG=236 YBD=1446 YHG=1417>in " XBD=365 XHG=299 YBD=1447 YHG=1416>the " XBD=471 XHG=390 YBD=1446 YHG=1425>arm " XBD=617 XHG=496 YBD=1447 YHG=1416>above " XBD=707 XHG=642 YBD=1446 YHG=1416>the " XBD=803 XHG=733 YBD=1446 YHG=1416>site " XBD=867 XHG=828 YBD=1446 YHG=1416>of " XBD=1060 XHG=890 YBD=1456 YHG=1415>ligation. " XBD=1300 XHG=1112 YBD=1455 YHG=1415>Injection " XBD=186 XHG=108 YBD=1492 YHG=1470>was " XBD=391 XHG=200 YBD=1501 YHG=1460>practised " XBD=475 XHG=406 YBD=1490 YHG=1461>not " XBD=582 XHG=493 YBD=1500 YHG=1460>only " XBD=690 XHG=597 YBD=1491 YHG=1460>with " XBD=757 XHG=708 YBD=1491 YHG=1470>an " XBD=895 XHG=773 YBD=1491 YHG=1460>intact " XBD=1055 XHG=911 YBD=1491 YHG=1470>venous " XBD=1214 XHG=1072 YBD=1500 YHG=1462>system " XBD=1301 XHG=1230 YBD=1492 YHG=1460>but " XBD=189 XHG=110 YBD=1536 YHG=1505>also " XBD=307 XHG=209 YBD=1536 YHG=1505>after " XBD=483 XHG=324 YBD=1545 YHG=1505>ligation " XBD=541 XHG=503 YBD=1536 YHG=1505>of " XBD=625 XHG=559 YBD=1536 YHG=1505>the " XBD=966 XHG=645 YBD=1546 YHG=1505>communicating " XBD=1072 XHG=984 YBD=1536 YHG=1505>vein " XBD=1168 XHG=1089 YBD=1545 YHG=1505>just " XBD=1303 XHG=1189 YBD=1536 YHG=1505>distal " XBD=152 XHG=111 YBD=1580 YHG=1550>to " XBD=233 XHG=182 YBD=1580 YHG=1550>its " XBD=509 XHG=263 YBD=1580 YHG=1549>termination " XBD=579 XHG=540 YBD=1580 YHG=1550>in " XBD=676 XHG=609 YBD=1580 YHG=1550>the " XBD=874 XHG=706 YBD=1589 YHG=1549>cephalic " XBD=946 XHG=906 YBD=1580 YHG=1559>or " XBD=1129 XHG=978 YBD=1580 YHG=1549>median " XBD=1304 XHG=1160 YBD=1581 YHG=1550>cubital " XBD=211 XHG=111 YBD=1631 YHG=1594>vein, " XBD=300 XHG=224 YBD=1625 YHG=1594>and " XBD=351 XHG=313 YBD=1625 YHG=1594>of " XBD=432 XHG=366 YBD=1624 YHG=1594>the " XBD=615 XHG=446 YBD=1625 YHG=1594>brachial " XBD=735 XHG=629 YBD=1625 YHG=1594>veins " XBD=831 XHG=751 YBD=1634 YHG=1594>just " XBD=968 XHG=847 YBD=1626 YHG=1594>above " XBD=1046 XHG=981 YBD=1625 YHG=1595>the " XBD=1132 XHG=1060 YBD=1625 YHG=1594>site " XBD=1186 XHG=1148 YBD=1625 YHG=1595>of |>" XBD=1303 XHG=1206 YBD=1628 YHG=1594>their " XBD=331 XHG=112 YBD=1670 YHG=1638>formation. " XBD=461 XHG=382 YBD=1669 YHG=1639>The " XBD=675 XHG=497 YBD=1675 YHG=1639>solution, " XBD=858 XHG=712 YBD=1679 YHG=1638>despite " XBD=999 XHG=893 YBD=1670 YHG=1639>these " XBD=1303 XHG=1036 YBD=1675 YHG=1639>obstructions, " XBD=373 XHG=112 YBD=1723 YHG=1682>immediately " XBD=552 XHG=397 YBD=1714 YHG=1683>entered " XBD=653 XHG=577 YBD=1713 YHG=1683>and " XBD=833 XHG=678 YBD=1715 YHG=1684>coursed " XBD=908 XHG=856 YBD=1723 YHG=1693>up " XBD=999 XHG=933 YBD=1714 YHG=1684>the " XBD=1104 XHG=1023 YBD=1714 YHG=1693>arm " XBD=1167 XHG=1128 YBD=1714 YHG=1683>in " XBD=1305 XHG=1192 YBD=1723 YHG=1693>every " XBD=296 XHG=113 YBD=1760 YHG=1727>instance. " XBD=495 XHG=328 YBD=1759 YHG=1727>Horwitz " XBD=706 XHG=508 YBD=1759 YHG=1727>concludes " XBD=804 XHG=717 YBD=1759 YHG=1728>that " XBD=837 XHG=816 YBD=1759 YHG=1738>a " XBD=946 XHG=848 YBD=1769 YHG=1728>good " XBD=1151 XHG=957 YBD=1759 YHG=1728>collateral " XBD=1305 XHG=1162 YBD=1760 YHG=1738>venous " XBD=336 XHG=115 YBD=1804 YHG=1773>circulation " XBD=555 XHG=368 YBD=1813 YHG=1772>normally " XBD=696 XHG=579 YBD=1803 YHG=1772>exists " XBD=766 XHG=727 YBD=1804 YHG=1772>in " XBD=864 XHG=798 YBD=1804 YHG=1774>the " XBD=1016 XHG=897 YBD=1805 YHG=1773>elbow " XBD=1188 XHG=1048 YBD=1814 YHG=1773>region, " XBD=1307 XHG=1223 YBD=1805 YHG=1773>well " XBD=312 XHG=113 YBD=1858 YHG=1818>protected |>" XBD=381 XHG=327 YBD=1859 YHG=1817>by " XBD=536 XHG=396 YBD=1848 YHG=1818>muscle " XBD=681 XHG=550 YBD=1857 YHG=1817>planes " XBD=773 XHG=697 YBD=1848 YHG=1817>and " XBD=970 XHG=798 YBD=1849 YHG=1818>external " XBD=1031 XHG=991 YBD=1849 YHG=1820>to " XBD=1123 XHG=1058 YBD=1849 YHG=1819>the " XBD=1307 XHG=1144 YBD=1849 YHG=1818>confines " XBD=157 XHG=117 YBD=1893 YHG=1862>of " XBD=247 XHG=179 YBD=1893 YHG=1862>the " XBD=508 XHG=271 YBD=1893 YHG=1862>antecubital " XBD=645 XHG=530 YBD=1893 YHG=1862>fossa. " XBD=775 XHG=696 YBD=1893 YHG=1862>The " XBD=1030 XHG=800 YBD=1894 YHG=1863>anatomical " XBD=1155 XHG=1054 YBD=1894 YHG=1863>basis " XBD=1219 XHG=1180 YBD=1893 YHG=1863>of " XBD=1308 XHG=1242 YBD=1893 YHG=1863>the " XBD=518 XHG=117 YBD=1938 YHG=1907>venous-obstruction " XBD=674 XHG=537 YBD=1947 YHG=1906>theory " XBD=733 XHG=694 YBD=1937 YHG=1907>of " XBD=1000 XHG=752 YBD=1938 YHG=1906>Volkmann’s " XBD=1259 XHG=1020 YBD=1938 YHG=1909>contracture " XBD=1310 XHG=1278 YBD=1938 YHG=1907>is " XBD=209 XHG=118 YBD=1982 YHG=1951>thus " XBD=501 XHG=240 YBD=1982 YHG=1951>undermined. " XBD=653 XHG=553 YBD=1982 YHG=1951>That " XBD=830 XHG=685 YBD=1982 YHG=1951>sudden " XBD=1135 XHG=862 YBD=1991 YHG=1952>experimental " XBD=1309 XHG=1165 YBD=1983 YHG=1961>venous " XBD=306 XHG=117 YBD=2028 YHG=1996>occlusion " XBD=416 XHG=326 YBD=2036 YHG=2006>may " XBD=602 XHG=435 YBD=2036 YHG=1996>produce " XBD=644 XHG=623 YBD=2027 YHG=2006>a " XBD=860 XHG=666 YBD=2027 YHG=1996>condition " XBD=1104 XHG=879 YBD=2037 YHG=1997>resembling " XBD=1310 XHG=1124 YBD=2028 YHG=1996>ischaemic " XBD=360 XHG=118 YBD=2072 YHG=2042>contracture " XBD=455 XHG=385 YBD=2082 YHG=2051>can " XBD=643 XHG=479 YBD=2081 YHG=2041>perhaps " XBD=715 XHG=668 YBD=2072 YHG=2041>be " XBD=940 XHG=740 YBD=2081 YHG=2040>explained " XBD=1130 XHG=964 YBD=2081 YHG=2041>through " XBD=1177 XHG=1155 YBD=2072 YHG=2051>a " XBD=1309 XHG=1201 YBD=2072 YHG=2051>vaso- " XBD=244 XHG=118 YBD=2116 YHG=2087>motor " XBD=403 XHG=276 YBD=2116 YHG=2085>reflex. " XBD=575 XHG=455 YBD=2116 YHG=2085>There " XBD=640 XHG=608 YBD=2116 YHG=2085>is " XBD=759 XHG=674 YBD=2116 YHG=2095>now " XBD=978 XHG=792 YBD=2116 YHG=2085>sufficient " XBD=1192 XHG=1012 YBD=2117 YHG=2086>evidence " XBD=1311 XHG=1225 YBD=2117 YHG=2086>that " XBD=270 XHG=117 YBD=2161 YHG=2131>trauma " XBD=335 XHG=294 YBD=2161 YHG=2131>to " XBD=410 XHG=360 YBD=2161 YHG=2139>an " XBD=562 XHG=435 YBD=2170 YHG=2131>artery " XBD=658 XHG=587 YBD=2161 YHG=2139>can " XBD=847 XHG=681 YBD=2170 YHG=2129>produce " XBD=986 XHG=870 YBD=2161 YHG=2130>reflex |>" XBD=1212 XHG=1009 YBD=2166 YHG=2130>ischemia, " XBD=1313 XHG=1237 YBD=2160 YHG=2130>and " XBD=184 XHG=116 YBD=2206 YHG=2174>the " XBD=404 XHG=207 YBD=2206 YHG=2174>otherwise " XBD=676 XHG=425 YBD=2215 YHG=2174>inexplicable " XBD=888 XHG=696 YBD=2218 YHG=2173>isohasmia " XBD=949 XHG=911 YBD=2206 YHG=2174>of " XBD=1037 XHG=971 YBD=2206 YHG=2174>the " XBD=1174 XHG=1058 YBD=2206 YHG=2175>white " XBD=1254 XHG=1194 YBD=2216 YHG=2175>leg " XBD=1314 XHG=1276 YBD=2205 YHG=2174>of " XBD=262 XHG=117 YBD=2251 YHG=2229>venous " XBD=509 XHG=278 YBD=2250 YHG=2219>thrombosis " XBD=596 XHG=526 YBD=2250 YHG=2220>has " XBD=691 XHG=613 YBD=2250 YHG=2219>also " XBD=805 XHG=709 YBD=2250 YHG=2219>been " XBD=1004 XHG=821 YBD=2260 YHG=2220>regarded " XBD=1063 XHG=1022 YBD=2251 YHG=2229>as " XBD=1259 XHG=1080 YBD=2250 YHG=2220>evidence " XBD=1316 XHG=1278 YBD=2250 YHG=2219>of " XBD=196 XHG=118 YBD=2295 YHG=2264>this " XBD=329 XHG=213 YBD=2295 YHG=2264>reflex " XBD=592 XHG=347 YBD=2295 YHG=2264>mechanism. CHRONIC INFLAMMATION " XBD=392 XHG=173 YBD=2429 YHG=2398>So-CALLED " XBD=562 XHG=411 YBD=2430 YHG=2399>chronic " XBD=860 XHG=577 YBD=2437 YHG=2397>inflammatory " XBD=1009 XHG=881 YBD=2434 YHG=2398>tissue, " XBD=1066 XHG=1027 YBD=2428 YHG=2398>of " XBD=1134 XHG=1085 YBD=2428 YHG=2407>no " XBD=1315 XHG=1156 YBD=2429 YHG=2398>discern- " XBD=198 XHG=96 YBD=2476 YHG=2442>ible " XBD=351 XHG=221 YBD=2483 YHG=2443>origin, " XBD=407 XHG=375 YBD=2474 YHG=2444>is " XBD=535 XHG=430 YBD=2474 YHG=2444>often " XBD=812 XHG=558 YBD=2474 YHG=2443>encountered " XBD=873 XHG=834 YBD=2472 YHG=2442>in " XBD=1039 XHG=895 YBD=2473 YHG=2442>human " XBD=1319 XHG=1061 YBD=2482 YHG=2441>pathological " XBD=310 XHG=125 YBD=2523 YHG=2487>material, " XBD=412 XHG=336 YBD=2518 YHG=2488>and " XBD=466 XHG=435 YBD=2518 YHG=2488>it " XBD=523 XHG=491 YBD=2519 YHG=2488>is " XBD=737 XHG=547 YBD=2528 YHG=2487>generally " XBD=932 XHG=757 YBD=2518 YHG=2487>assumed " XBD=1043 XHG=956 YBD=2517 YHG=2486>that " XBD=1134 XHG=1068 YBD=2517 YHG=2486>the " XBD=1318 XHG=1158 YBD=2517 YHG=2483>cause- " XBD=317 XHG=122 YBD=2563 YHG=2531>whatever " XBD=360 XHG=329 YBD=2563 YHG=2532>it " XBD=487 XHG=373 YBD=2563 YHG=2533>is-is " XBD=680 XHG=501 YBD=2563 YHG=2531>extrinsic " XBD=769 XHG=693 YBD=2563 YHG=2532>and " XBD=869 XHG=782 YBD=2563 YHG=2532>that " XBD=948 XHG=883 YBD=2562 YHG=2531>the " XBD=1076 XHG=963 YBD=2571 YHG=2532>agent " XBD=1319 XHG=1088 YBD=2570 YHG=2530>responsible " XBD=262 XHG=127 YBD=2607 YHG=2576>should " XBD=331 XHG=285 YBD=2607 YHG=2576>be " XBD=587 XHG=353 YBD=2608 YHG=2576>identifiable " XBD=648 XHG=608 YBD=2607 YHG=2576>in " XBD=736 XHG=671 YBD=2607 YHG=2577>the " XBD=1042 XHG=758 YBD=2615 YHG=2577>inflammatory " XBD=1182 XHG=1065 YBD=2606 YHG=2575>tissue " XBD=1318 XHG=1204 YBD=2606 YHG=2575>itself. " XBD=315 XHG=125 YBD=2661 YHG=2620>Pullinger " XBD=413 XHG=337 YBD=2651 YHG=2621>and Pirie " XBD=681 XHG=548 YBD=2653 YHG=2622>2 have " XBD=883 XHG=702 YBD=2652 YHG=2620>obtained " XBD=1083 XHG=905 YBD=2651 YHG=2620>evidence " XBD=1146 XHG=1104 YBD=2651 YHG=2622>to " XBD=1319 XHG=1168 YBD=2660 YHG=2621>suggest " XBD=214 XHG=125 YBD=2696 YHG=2665>that " XBD=478 XHG=234 YBD=2704 YHG=2665>non-specific " XBD=651 XHG=499 YBD=2697 YHG=2666>chronic " XBD=949 XHG=672 YBD=2696 YHG=2665>inflammation " XBD=1060 XHG=972 YBD=2704 YHG=2674>may " XBD=1128 XHG=1081 YBD=2695 YHG=2665>be " XBD=1319 XHG=1148 YBD=2696 YHG=2664>intrinsic " XBD=166 XHG=127 YBD=2740 YHG=2709>in " XBD=304 XHG=185 YBD=2749 YHG=2709>origin " XBD=399 XHG=323 YBD=2740 YHG=2710>and " XBD=521 XHG=418 YBD=2740 YHG=2719>more " XBD=664 XHG=540 YBD=2741 YHG=2710>subtle " XBD=778 XHG=682 YBD=2741 YHG=2710>than " XBD=827 XHG=795 YBD=2741 YHG=2710>is " XBD=994 XHG=845 YBD=2749 YHG=2709>usually " XBD=1225 XHG=1013 YBD=2749 YHG=2708>suspected, " XBD=1320 XHG=1244 YBD=2740 YHG=2708>and " XBD=214 XHG=127 YBD=2785 YHG=2754>that " XBD=274 XHG=242 YBD=2784 YHG=2754>it " XBD=393 XHG=304 YBD=2793 YHG=2763>may " XBD=558 XHG=422 YBD=2794 YHG=2754>persist " XBD=646 XHG=587 YBD=2785 YHG=2754>for " XBD=697 XHG=676 YBD=2785 YHG=2764>a " XBD=815 XHG=726 YBD=2794 YHG=2754>long " XBD=936 XHG=843 YBD=2785 YHG=2755>time " XBD=1064 XHG=966 YBD=2785 YHG=2754>after " XBD=1158 XHG=1092 YBD=2784 YHG=2754>the " XBD=1321 XHG=1187 YBD=2785 YHG=2753>visible " XBD=322 XHG=129 YBD=2830 YHG=2798>causative " XBD=461 XHG=348 YBD=2838 YHG=2800>agent " XBD=557 XHG=487 YBD=2829 YHG=2798>has " XBD=843 XHG=583 YBD=2838 YHG=2799>disappeared. " XBD=1000 XHG=896 YBD=2838 YHG=2799>They " XBD=1137 XHG=1026 YBD=2829 YHG=2799>made " XBD=1184 XHG=1162 YBD=2828 YHG=2808>a " XBD=1321 XHG=1211 YBD=2829 YHG=2798>series " XBD=168 XHG=130 YBD=2874 YHG=2843>of " XBD=486 XHG=197 YBD=2883 YHG=2842>implantations " XBD=556 XHG=518 YBD=2873 YHG=2843>of " XBD=711 XHG=586 YBD=2873 YHG=2843>sterile " XBD=902 XHG=741 YBD=2882 YHG=2843>purified " XBD=1099 XHG=931 YBD=2882 YHG=2843>collagen " XBD=1226 XHG=1128 YBD=2873 YHG=2843>from " XBD=1322 XHG=1255 YBD=2873 YHG=2842>the " XBD=265 XHG=130 YBD=2918 YHG=2896>cornea " XBD=322 XHG=284 YBD=2918 YHG=2887>of " XBD=406 XHG=339 YBD=2917 YHG=2887>the " XBD=473 XHG=425 YBD=2917 YHG=2896>ox " XBD=662 XHG=491 YBD=2918 YHG=2887>between " XBD=746 XHG=680 YBD=2917 YHG=2887>the " XBD=902 XHG=765 YBD=2918 YHG=2887>dermis " XBD=996 XHG=920 YBD=2917 YHG=2887>and " XBD=1080 XHG=1013 YBD=2918 YHG=2887>the " XBD=1322 XHG=1097 YBD=2926 YHG=2886>panniculus " XBD=309 XHG=132 YBD=2962 YHG=2941>carnosus " XBD=377 XHG=338 YBD=2962 YHG=2931>of " XBD=562 XHG=404 YBD=2961 YHG=2931>rabbits. " XBD=758 XHG=614 YBD=2970 YHG=2931>Biopsy " XBD=993 XHG=786 YBD=2971 YHG=2932>specimens " XBD=1116 XHG=1019 YBD=2962 YHG=2941>were " XBD=1322 XHG=1143 YBD=2962 YHG=2931>removed " XBD=171 XHG=131 YBD=3006 YHG=2977>at " XBD=350 XHG=205 YBD=3015 YHG=2975>weekly " XBD=567 XHG=385 YBD=3006 YHG=2975>intervals " XBD=680 XHG=604 YBD=3006 YHG=2975>and " XBD=738 XHG=715 YBD=3005 YHG=2985>a " XBD=876 XHG=773 YBD=3006 YHG=2984>more " XBD=954 XHG=913 YBD=3006 YHG=2985>or " XBD=1061 XHG=989 YBD=3006 YHG=2975>less " XBD=1323 XHG=1096 YBD=3006 YHG=2975>continuous " XBD=366 XHG=130 YBD=3060 YHG=3019>histological " XBD=551 XHG=404 YBD=3059 YHG=3016>picture " XBD=628 XHG=591 YBD=3049 YHG=3019>of " XBD=733 XHG=667 YBD=3049 YHG=3019>the " XBD=923 XHG=771 YBD=3050 YHG=3019>cellular " XBD=1129 XHG=961 YBD=3050 YHG=3020>reaction " XBD=1243 XHG=1166 YBD=3051 YHG=3029>was " XBD=1323 XHG=1283 YBD=3050 YHG=3029>so " XBD=325 XHG=132 YBD=3095 YHG=3064>obtained. " XBD=455 XHG=376 YBD=3094 YHG=3064>The |>" XBD=659 XHG=477 YBD=3103 YHG=3062>implants " XBD=776 XHG=680 YBD=3094 YHG=3072>were " XBD=947 XHG=797 YBD=3103 YHG=3064>rapidly " XBD=1205 XHG=971 YBD=3095 YHG=3064>surrounded " XBD=1279 XHG=1227 YBD=3103 YHG=3064>by " XBD=1324 XHG=1302 YBD=3095 YHG=3074>a " XBD=284 XHG=132 YBD=3139 YHG=3108>cellular " XBD=382 XHG=306 YBD=3139 YHG=3108>and " XBD=544 XHG=403 YBD=3139 YHG=3108>fibrous " XBD=739 XHG=565 YBD=3138 YHG=3107>vascular " XBD=924 XHG=761 YBD=3147 YHG=3107>capsule, " XBD=1069 XHG=946 YBD=3139 YHG=3108>which " XBD=1143 XHG=1090 YBD=3148 YHG=3108>by " XBD=1230 XHG=1164 YBD=3139 YHG=3108>the " XBD=1325 XHG=1252 YBD=3139 YHG=3108>end " XBD=171 XHG=133 YBD=3184 YHG=3152>of " XBD=263 XHG=197 YBD=3183 YHG=3152>the " XBD=420 XHG=289 YBD=3183 YHG=3152>fourth " XBD=550 XHG=445 YBD=3184 YHG=3152>week " XBD=698 XHG=576 YBD=3192 YHG=3152>began " XBD=765 XHG=724 YBD=3182 YHG=3153>to " XBD=846 XHG=791 YBD=3182 YHG=3152>fill " XBD=922 XHG=870 YBD=3192 YHG=3162>up " XBD=1042 XHG=948 YBD=3184 YHG=3152>with " XBD=1169 XHG=1068 YBD=3193 YHG=3152>large " XBD=1326 XHG=1195 YBD=3193 YHG=3153>foamy |>" XBD=75 XHG=71 YBD=3216 YHG=3205>’ " XBD=403 XHG=134 YBD=3237 YHG=3197>macrophages " XBD=692 XHG=423 YBD=3237 YHG=3196>accompanied " XBD=764 XHG=711 YBD=3236 YHG=3196>by " XBD=1049 XHG=783 YBD=3237 YHG=3196>lymphocytes " XBD=1145 XHG=1069 YBD=3228 YHG=3198>and " XBD=1325 XHG=1163 YBD=3237 YHG=3198>plasma- " XBD=232 XHG=134 YBD=3272 YHG=3241>cells. " XBD=460 XHG=286 YBD=3281 YHG=3241>Collagen " XBD=609 XHG=497 YBD=3272 YHG=3242>fibres " XBD=724 XHG=646 YBD=3272 YHG=3240>had " XBD=1010 XHG=762 YBD=3280 YHG=3240>disappeared " XBD=1099 XHG=1047 YBD=3281 YHG=3241>by " XBD=1203 XHG=1137 YBD=3272 YHG=3242>the " XBD=1326 XHG=1239 YBD=3272 YHG=3241>fifth " XBD=248 XHG=132 YBD=3321 YHG=3284>week, " XBD=356 XHG=286 YBD=3316 YHG=3285>but " XBD=459 XHG=393 YBD=3315 YHG=3285>the " XBD=768 XHG=499 YBD=3325 YHG=3285>macrophages " XBD=1007 XHG=805 YBD=3315 YHG=3285>contained " XBD=1252 XHG=1045 YBD=3325 YHG=3286>fragments " XBD=1329 XHG=1290 YBD=3316 YHG=3286>of " XBD=309 XHG=136 YBD=3360 YHG=3328>material " XBD=548 XHG=319 YBD=3370 YHG=3320>responding " XBD=600 XHG=559 YBD=3360 YHG=3331>to " XBD=781 XHG=614 YBD=3369 YHG=3329>collagen " XBD=924 XHG=794 YBD=3366 YHG=3329>stains, " XBD=1014 XHG=939 YBD=3360 YHG=3330>and " XBD=1133 XHG=1027 YBD=3361 YHG=3330>these " XBD=1329 XHG=1144 YBD=3370 YHG=3330>persisted " XBD=296 XHG=133 YBD=3405 YHG=3373>without " XBD=537 XHG=325 YBD=3415 YHG=3374>significant " XBD=710 XHG=567 YBD=3414 YHG=3374>change " XBD=839 XHG=738 YBD=3405 YHG=3374>until " XBD=931 XHG=865 YBD=3404 YHG=3374>the " XBD=1034 XHG=960 YBD=3405 YHG=3375>end " XBD=1102 XHG=1064 YBD=3405 YHG=3375>of " XBD=1196 XHG=1129 YBD=3405 YHG=3375>the " XBD=1328 XHG=1224 YBD=3405 YHG=3374>third 1. Horwitz, T. Surg. Gynec. Obstet. 1942, 74, 871. 2. Pullinger, B. D. and Pirie, A. J. Path. Bact. 1942, 54, 341. " XBD=1493 XHG=1347 YBD=218 YHG=184>month, " XBD=1636 XHG=1514 YBD=215 YHG=184>which " XBD=1687 XHG=1656 YBD=214 YHG=185>is " XBD=1748 XHG=1707 YBD=214 YHG=193>as " XBD=1826 XHG=1768 YBD=214 YHG=185>far " XBD=1887 XHG=1846 YBD=215 YHG=194>as " XBD=1973 XHG=1907 YBD=215 YHG=184>the " XBD=2260 XHG=1992 YBD=221 YHG=184>investigation " XBD=2354 XHG=2278 YBD=214 YHG=193>was " XBD=2519 XHG=2374 YBD=214 YHG=184>carried. " XBD=1456 XHG=1346 YBD=259 YHG=227>After " XBD=1635 XHG=1482 YBD=267 YHG=228>making " XBD=1863 XHG=1663 YBD=259 YHG=228>allowance " XBD=1948 XHG=1889 YBD=258 YHG=228>for " XBD=2096 XHG=1974 YBD=258 YHG=228>minor " XBD=2336 XHG=2122 YBD=258 YHG=228>differences " XBD=2520 XHG=2361 YBD=258 YHG=227>between " XBD=1475 XHG=1347 YBD=302 YHG=271>rabbit " XBD=1585 XHG=1510 YBD=303 YHG=272>and " XBD=1761 XHG=1617 YBD=302 YHG=272>human " XBD=1984 XHG=1795 YBD=311 YHG=272>cytology, " XBD=2085 XHG=2019 YBD=302 YHG=272>the " XBD=2266 XHG=2118 YBD=311 YHG=271>general " XBD=2523 XHG=2297 YBD=310 YHG=270>histological " XBD=1495 XHG=1348 YBD=355 YHG=316>picture " XBD=1615 XHG=1519 YBD=346 YHG=316>after " XBD=1703 XHG=1638 YBD=346 YHG=316>the " XBD=1855 XHG=1725 YBD=346 YHG=316>fourth " XBD=1992 XHG=1877 YBD=351 YHG=316>week, " XBD=2125 XHG=2016 YBD=346 YHG=316>when " XBD=2212 XHG=2147 YBD=346 YHG=316>the " XBD=2398 XHG=2235 YBD=354 YHG=314>collagen " XBD=2522 XHG=2420 YBD=346 YHG=314>fibres " XBD=1610 XHG=1350 YBD=399 YHG=360>disappeared, " XBD=1718 XHG=1641 YBD=391 YHG=369>was " XBD=1888 XHG=1750 YBD=398 YHG=359>closely " XBD=2158 XHG=1919 YBD=398 YHG=359>comparable " XBD=2229 XHG=2189 YBD=389 YHG=360>to " XBD=2346 XHG=2261 YBD=388 YHG=359>that " XBD=2460 XHG=2378 YBD=388 YHG=367>seen |>" XBD=2524 XHG=2489 YBD=389 YHG=358>ih " XBD=1493 XHG=1348 YBD=434 YHG=403>human " XBD=1755 XHG=1513 YBD=442 YHG=403>non-specific " XBD=2065 XHG=1776 YBD=433 YHG=403>inflammation. " XBD=2290 XHG=2118 YBD=442 YHG=402>Collagen " XBD=2342 XHG=2310 YBD=432 YHG=402>is " XBD=2384 XHG=2362 YBD=431 YHG=411>a " XBD=2525 XHG=2403 YBD=441 YHG=402>highly " XBD=1527 XHG=1348 YBD=477 YHG=448>resistant " XBD=1772 XHG=1547 YBD=477 YHG=447>substance : " XBD=1837 XHG=1807 YBD=477 YHG=447>it " XBD=1887 XHG=1856 YBD=476 YHG=447>is " XBD=1953 XHG=1905 YBD=476 YHG=456>no " XBD=2075 XHG=1974 YBD=477 YHG=456>more " XBD=2188 XHG=2094 YBD=476 YHG=446>than " XBD=2329 XHG=2206 YBD=485 YHG=445>feebly " XBD=2525 XHG=2348 YBD=476 YHG=445>dissolved " XBD=1402 XHG=1349 YBD=530 YHG=491>by " XBD=1502 XHG=1426 YBD=530 YHG=500>any " XBD=1663 XHG=1526 YBD=521 YHG=491>known " XBD=1913 XHG=1686 YBD=530 YHG=490>proteolytic " XBD=2093 XHG=1937 YBD=530 YHG=500>enzyme " XBD=2237 XHG=2115 YBD=520 YHG=490>which " XBD=2380 XHG=2259 YBD=520 YHG=489>works " XBD=2527 XHG=2402 YBD=520 YHG=489>within " XBD=1416 XHG=1327 YBD=565 YHG=535>the " XBD=1754 XHG=1444 YBD=574 YHG=535>neighbourhood " XBD=1822 XHG=1783 YBD=564 YHG=535>of " XBD=2069 XHG=1849 YBD=573 YHG=534>neutrality. " XBD=2309 XHG=2121 YBD=572 YHG=533>Pullinger " XBD=2411 XHG=2337 YBD=563 YHG=533>and " XBD=2527 XHG=2437 YBD=564 YHG=533>Pirie " XBD=1502 XHG=1351 YBD=617 YHG=580>suggest " XBD=1607 XHG=1520 YBD=608 YHG=579>that " XBD=1656 XHG=1625 YBD=608 YHG=578>it " XBD=1705 XHG=1674 YBD=608 YHG=578>is " XBD=1788 XHG=1723 YBD=608 YHG=578>the " XBD=1964 XHG=1806 YBD=608 YHG=578>relative " XBD=2215 XHG=1981 YBD=615 YHG=577>insolubility " XBD=2272 XHG=2234 YBD=607 YHG=577>of " XBD=2354 XHG=2289 YBD=607 YHG=577>the " XBD=2528 XHG=2372 YBD=616 YHG=576>collagen " XBD=1439 XHG=1352 YBD=652 YHG=622>that " XBD=1493 XHG=1462 YBD=652 YHG=622>is " XBD=1746 XHG=1515 YBD=660 YHG=621>responsible " XBD=1827 XHG=1768 YBD=651 YHG=622>for " XBD=1915 XHG=1849 YBD=651 YHG=622>the " XBD=2106 XHG=1938 YBD=652 YHG=621>reaction " XBD=2205 XHG=2130 YBD=651 YHG=620>and " XBD=2277 XHG=2227 YBD=651 YHG=620>its " XBD=2528 XHG=2299 YBD=659 YHG=620>persistence, " XBD=1429 XHG=1353 YBD=696 YHG=665>and " XBD=1533 XHG=1446 YBD=696 YHG=666>that " XBD=1600 XHG=1552 YBD=696 YHG=675>an " XBD=1821 XHG=1619 YBD=696 YHG=665>alteration " XBD=1877 XHG=1838 YBD=695 YHG=665>in " XBD=1961 XHG=1895 YBD=695 YHG=665>the " XBD=2316 XHG=1978 YBD=704 YHG=664>physicochemical " XBD=2530 XHG=2332 YBD=704 YHG=665>properties " XBD=1392 XHG=1353 YBD=740 YHG=709>of " XBD=1471 XHG=1405 YBD=740 YHG=709>the " XBD=1666 XHG=1486 YBD=749 YHG=709>subject’s " XBD=1764 XHG=1681 YBD=740 YHG=719>own " XBD=1849 XHG=1778 YBD=740 YHG=709>less " XBD=2007 XHG=1865 YBD=739 YHG=709>soluble " XBD=2228 XHG=2023 YBD=739 YHG=710>structures " XBD=2330 XHG=2244 YBD=747 YHG=717>may " XBD=2383 XHG=2345 YBD=738 YHG=708>in " XBD=2530 XHG=2397 YBD=739 YHG=709>certain " XBD=1455 XHG=1353 YBD=784 YHG=762>cases " XBD=1616 XHG=1467 YBD=784 YHG=753>initiate " XBD=1671 XHG=1629 YBD=784 YHG=754>it. " XBD=1828 XHG=1724 YBD=792 YHG=753>They " XBD=1890 XHG=1842 YBD=784 YHG=753>do " XBD=1971 XHG=1903 YBD=783 YHG=754>not " XBD=2094 XHG=1983 YBD=783 YHG=753>think " XBD=2193 XHG=2106 YBD=783 YHG=753>that " XBD=2271 XHG=2205 YBD=783 YHG=752>the " XBD=2531 XHG=2281 YBD=792 YHG=752>heterologous " XBD=1472 XHG=1354 YBD=837 YHG=797>origin " XBD=1538 XHG=1500 YBD=828 YHG=797>of " XBD=1629 XHG=1564 YBD=828 YHG=798>the " XBD=1823 XHG=1657 YBD=837 YHG=797>collagen " XBD=1988 XHG=1848 YBD=837 YHG=797>played " XBD=2036 XHG=2014 YBD=827 YHG=806>a " XBD=2274 XHG=2063 YBD=836 YHG=796>significant " XBD=2385 XHG=2300 YBD=835 YHG=798>part " XBD=2448 XHG=2410 YBD=827 YHG=796>in " XBD=2531 XHG=2472 YBD=828 YHG=798>the " XBD=1534 XHG=1353 YBD=877 YHG=842>reaction, " XBD=1704 XHG=1559 YBD=881 YHG=841>though " XBD=1866 XHG=1728 YBD=881 YHG=841>ideally " XBD=1912 XHG=1890 YBD=871 YHG=850>a " XBD=2082 XHG=1935 YBD=871 YHG=841>control " XBD=2213 XHG=2104 YBD=880 YHG=841>using " XBD=2474 XHG=2235 YBD=880 YHG=840>homologous " XBD=2533 XHG=2496 YBD=873 YHG=851>or " XBD=1450 XHG=1356 YBD=916 YHG=894>even " XBD=1709 XHG=1485 YBD=925 YHG=885>autologous " XBD=1911 XHG=1744 YBD=926 YHG=885>collagen " XBD=2127 XHG=1944 YBD=925 YHG=884>implants " XBD=2284 XHG=2159 YBD=916 YHG=884>would " XBD=2414 XHG=2317 YBD=916 YHG=884>have " XBD=2532 XHG=2446 YBD=918 YHG=886>been " XBD=1550 XHG=1356 YBD=960 YHG=929>desirable. " XBD=1714 XHG=1603 YBD=960 YHG=930>Their " XBD=1853 XHG=1736 YBD=970 YHG=940>paper " XBD=1943 XHG=1874 YBD=961 YHG=930>has " XBD=1992 XHG=1970 YBD=960 YHG=939>a " XBD=2172 XHG=2017 YBD=970 YHG=929>bearing " XBD=2243 XHG=2195 YBD=960 YHG=939>on " XBD=2532 XHG=2266 YBD=971 YHG=929>skin-grafting, " XBD=1455 XHG=1355 YBD=1005 YHG=974>since " XBD=1571 XHG=1479 YBD=1005 YHG=974>such " XBD=1713 XHG=1594 YBD=1014 YHG=974>grafts " XBD=1890 XHG=1737 YBD=1005 YHG=974>contain " XBD=1935 XHG=1913 YBD=1005 YHG=984>a " XBD=2048 XHG=1958 YBD=1014 YHG=974>high " XBD=2294 XHG=2070 YBD=1014 YHG=976>percentage " XBD=2356 XHG=2318 YBD=1005 YHG=974>of " XBD=2533 XHG=2378 YBD=1015 YHG=974>collagen " XBD=1432 XHG=1356 YBD=1049 YHG=1018>and " XBD=1514 XHG=1452 YBD=1049 YHG=1027>are " XBD=1639 XHG=1534 YBD=1049 YHG=1018>often " XBD=1735 XHG=1658 YBD=1049 YHG=1018>laid " XBD=1914 XHG=1755 YBD=1058 YHG=1019>directly " XBD=1982 XHG=1933 YBD=1051 YHG=1028>on " XBD=2067 XHG=2001 YBD=1049 YHG=1019>the " XBD=2231 XHG=2087 YBD=1049 YHG=1018>surface " XBD=2289 XHG=2252 YBD=1048 YHG=1018>of " XBD=2535 XHG=2307 YBD=1058 YHG=1018>granulation " XBD=1486 XHG=1357 YBD=1093 YHG=1063>tissue. PROPHYLACTIC TETANUS ANTITOXIN " XBD=1493 XHG=1407 YBD=1226 YHG=1195>THE " XBD=1603 XHG=1511 YBD=1226 YHG=1195>War " XBD=1738 XHG=1623 YBD=1226 YHG=1194>Office " XBD=1920 XHG=1755 YBD=1226 YHG=1195>reminds " XBD=2099 XHG=1938 YBD=1226 YHG=1195>medical |>" XBD=2273 XHG=2116 YBD=1227 YHG=1195>officers1 " XBD=2376 XHG=2290 YBD=1226 YHG=1195>that " XBD=2537 XHG=2393 YBD=1228 YHG=1196>tetanus " XBD=1552 XHG=1359 YBD=1270 YHG=1239>antitoxin " XBD=1712 XHG=1577 YBD=1270 YHG=1239>should " XBD=1783 XHG=1736 YBD=1270 YHG=1235>be " XBD=1918 XHG=1807 YBD=1279 YHG=1239>given " XBD=1983 XHG=1943 YBD=1270 YHG=1241>to " XBD=2060 XHG=2009 YBD=1277 YHG=1239>all " XBD=2206 XHG=2082 YBD=1271 YHG=1239>battle " XBD=2427 XHG=2230 YBD=1271 YHG=1239>casualties " XBD=2535 XHG=2450 YBD=1272 YHG=1250>even " XBD=1506 XHG=1359 YBD=1323 YHG=1284>though " XBD=1608 XHG=1515 YBD=1324 YHG=1284>they " XBD=1716 XHG=1617 YBD=1315 YHG=1283>have " XBD=1803 XHG=1726 YBD=1315 YHG=1283>had " XBD=1969 XHG=1815 YBD=1315 YHG=1285>tetanus " XBD=2112 XHG=1979 YBD=1314 YHG=1283>toxoid " XBD=2160 XHG=2121 YBD=1315 YHG=1283>in " XBD=2235 XHG=2169 YBD=1315 YHG=1284>the " XBD=2332 XHG=2244 YBD=1323 YHG=1285>past " XBD=2383 XHG=2343 YBD=1315 YHG=1293>or " XBD=2539 XHG=2395 YBD=1316 YHG=1285>tetanus " XBD=1552 XHG=1361 YBD=1359 YHG=1328>antitoxin " XBD=1757 XHG=1577 YBD=1368 YHG=1328>recently. " XBD=1846 XHG=1810 YBD=1359 YHG=1328>It " XBD=2003 XHG=1866 YBD=1359 YHG=1327>should " XBD=2098 XHG=2020 YBD=1359 YHG=1328>also " XBD=2165 XHG=2118 YBD=1359 YHG=1328>be " XBD=2303 XHG=2192 YBD=1369 YHG=1329>given " XBD=2360 XHG=2319 YBD=1359 YHG=1330>to " XBD=2539 XHG=2382 YBD=1368 YHG=1329>patients " XBD=1540 XHG=1361 YBD=1413 YHG=1372>suffering " XBD=1648 XHG=1549 YBD=1404 YHG=1373>from " XBD=1735 XHG=1660 YBD=1412 YHG=1382>any " XBD=1884 XHG=1745 YBD=1404 YHG=1373>wound " XBD=2016 XHG=1893 YBD=1404 YHG=1372>which " XBD=2147 XHG=2028 YBD=1405 YHG=1382>seems " XBD=2272 XHG=2156 YBD=1412 YHG=1373>likely " XBD=2322 XHG=2281 YBD=1404 YHG=1375>to " XBD=2380 XHG=2333 YBD=1404 YHG=1373>be " XBD=2539 XHG=2386 YBD=1405 YHG=1373>infected " XBD=1453 XHG=1359 YBD=1449 YHG=1417>with " XBD=1637 XHG=1472 YBD=1448 YHG=1419>tetanus. " XBD=1811 XHG=1688 YBD=1449 YHG=1417>When " XBD=2015 XHG=1825 YBD=1448 YHG=1417>antitoxin " XBD=2059 XHG=2028 YBD=1448 YHG=1418>is " XBD=2184 XHG=2072 YBD=1457 YHG=1417>given " XBD=2507 XHG=2198 YBD=1458 YHG=1417>subcutaneously " XBD=2540 XHG=2520 YBD=1449 YHG=1428>a " XBD=1572 XHG=1362 YBD=1493 YHG=1462>maximum " XBD=1685 XHG=1588 YBD=1493 YHG=1461>level " XBD=1740 XHG=1700 YBD=1492 YHG=1461>in " XBD=1822 XHG=1756 YBD=1493 YHG=1461>the " XBD=1953 XHG=1839 YBD=1492 YHG=1461>blood " XBD=2000 XHG=1970 YBD=1493 YHG=1462>is " XBD=2085 XHG=2017 YBD=1493 YHG=1463>not " XBD=2266 XHG=2104 YBD=1493 YHG=1462>reached " XBD=2341 XHG=2282 YBD=1493 YHG=1462>for " XBD=2427 XHG=2360 YBD=1493 YHG=1463>3-4 " XBD=2540 XHG=2443 YBD=1502 YHG=1462>days, " XBD=1527 XHG=1361 YBD=1538 YHG=1506>whereas " XBD=1573 XHG=1543 YBD=1537 YHG=1507>if " XBD=1618 XHG=1587 YBD=1537 YHG=1507>it " XBD=1665 XHG=1633 YBD=1537 YHG=1506>is " XBD=1792 XHG=1680 YBD=1546 YHG=1506>given " XBD=1860 XHG=1808 YBD=1546 YHG=1506>by " XBD=1970 XHG=1877 YBD=1546 YHG=1506>deep " XBD=2278 XHG=1986 YBD=1538 YHG=1506>intramuscular " XBD=2468 XHG=2292 YBD=1547 YHG=1506>injection " XBD=2541 XHG=2483 YBD=1539 YHG=1508>the " XBD=1467 XHG=1364 YBD=1582 YHG=1561>same " XBD=1534 XHG=1493 YBD=1582 YHG=1561>or " XBD=1583 XHG=1561 YBD=1582 YHG=1561>a " XBD=1739 XHG=1607 YBD=1591 YHG=1551>higher " XBD=1860 XHG=1763 YBD=1582 YHG=1551>level " XBD=1915 XHG=1884 YBD=1582 YHG=1551>is " XBD=2100 XHG=1940 YBD=1582 YHG=1551>reached " XBD=2239 XHG=2126 YBD=1582 YHG=1551>much " XBD=2367 XHG=2265 YBD=1582 YHG=1560>more " XBD=2542 XHG=2391 YBD=1591 YHG=1551>rapidly, " XBD=1603 XHG=1366 YBD=1636 YHG=1596>appreciable " XBD=1836 XHG=1630 YBD=1635 YHG=1596>quantities " XBD=1900 XHG=1861 YBD=1626 YHG=1595>of " XBD=2115 XHG=1924 YBD=1627 YHG=1596>antitoxin " XBD=2251 XHG=2139 YBD=1636 YHG=1596>being " XBD=2542 XHG=2276 YBD=1627 YHG=1596>demonstrable " XBD=1405 XHG=1365 YBD=1672 YHG=1642>in " XBD=1495 XHG=1429 YBD=1671 YHG=1641>the " XBD=1633 XHG=1520 YBD=1671 YHG=1640>blood " XBD=1791 XHG=1657 YBD=1672 YHG=1640>within " XBD=1838 XHG=1816 YBD=1671 YHG=1650>a " XBD=1934 XHG=1861 YBD=1671 YHG=1640>few " XBD=2083 XHG=1957 YBD=1672 YHG=1641>hours. " XBD=2239 XHG=2135 YBD=1680 YHG=1641>Deep " XBD=2543 XHG=2265 YBD=1671 YHG=1640>intramuscular " XBD=1679 XHG=1365 YBD=1725 YHG=1685>injection-into " XBD=1778 XHG=1712 YBD=1716 YHG=1685>the " XBD=1987 XHG=1811 YBD=1721 YHG=1684>deltoid, " XBD=2065 XHG=1999 YBD=1716 YHG=1685>the " XBD=2342 XHG=2098 YBD=1725 YHG=1685>subscapular " XBD=2414 XHG=2374 YBD=1715 YHG=1694>or " XBD=2543 XHG=2446 YBD=1715 YHG=1686>outer " XBD=1559 XHG=1369 YBD=1770 YHG=1730>quadrant " XBD=1616 XHG=1578 YBD=1761 YHG=1730>of " XBD=1698 XHG=1632 YBD=1761 YHG=1729>the " XBD=1858 XHG=1716 YBD=1770 YHG=1729>gluteal " XBD=2208 XHG=1874 YBD=1770 YHG=1729>regions-should " XBD=2409 XHG=2224 YBD=1761 YHG=1729>therefore " XBD=2470 XHG=2425 YBD=1760 YHG=1729>be " XBD=2546 XHG=2486 YBD=1760 YHG=1729>the " XBD=1516 XHG=1368 YBD=1807 YHG=1775>normal " XBD=1709 XHG=1560 YBD=1813 YHG=1777>route ; " XBD=2017 XHG=1770 YBD=1806 YHG=1775>intravenous " XBD=2368 XHG=2063 YBD=1806 YHG=1774>administration " XBD=2442 XHG=2411 YBD=1805 YHG=1774>is " XBD=2546 XHG=2484 YBD=1805 YHG=1776>not " XBD=1659 XHG=1368 YBD=1851 YHG=1820>recommended " XBD=1759 XHG=1698 YBD=1860 YHG=1820>for |>" XBD=2051 XHG=1799 YBD=1861 YHG=1820>prophylactic " XBD=2159 XHG=2095 YBD=1852 YHG=1830>use " XBD=2363 XHG=2203 YBD=1851 YHG=1819>because " XBD=2445 XHG=2406 YBD=1850 YHG=1819>of " XBD=2545 XHG=2486 YBD=1850 YHG=1819>the " XBD=1583 XHG=1368 YBD=1905 YHG=1864>possibility " XBD=1637 XHG=1598 YBD=1895 YHG=1864>of " XBD=1918 XHG=1652 YBD=1904 YHG=1864>anaphylactic " XBD=2111 XHG=1931 YBD=1895 YHG=1864>reaction. " XBD=2242 XHG=2163 YBD=1895 YHG=1864>The " XBD=2451 XHG=2257 YBD=1895 YHG=1864>minimum " XBD=2547 XHG=2467 YBD=1894 YHG=1863>dose " XBD=1506 XHG=1370 YBD=1940 YHG=1909>should " XBD=1582 XHG=1534 YBD=1940 YHG=1909>be " XBD=1705 XHG=1613 YBD=1940 YHG=1910>3000 " XBD=1849 XHG=1734 YBD=1945 YHG=1909>units, " XBD=1950 XHG=1880 YBD=1939 YHG=1909>but " XBD=2056 XHG=1979 YBD=1939 YHG=1909>this " XBD=2220 XHG=2086 YBD=1939 YHG=1909>should " XBD=2296 XHG=2249 YBD=1939 YHG=1908>be " XBD=2484 XHG=2326 YBD=1939 YHG=1908>doubled " XBD=2547 XHG=2512 YBD=1938 YHG=1917>or " XBD=1517 XHG=1369 YBD=1985 YHG=1953>trebled " XBD=1659 XHG=1535 YBD=1985 YHG=1953>where " XBD=1784 XHG=1678 YBD=1985 YHG=1954>there " XBD=1867 XHG=1805 YBD=1985 YHG=1963>are " XBD=1980 XHG=1887 YBD=1993 YHG=1962>very " XBD=2079 XHG=1997 YBD=1984 YHG=1953>foul " XBD=2285 XHG=2096 YBD=1984 YHG=1953>lacerated " XBD=2469 XHG=2303 YBD=1984 YHG=1952>wounds. " XBD=2548 XHG=2518 YBD=1982 YHG=1952>If " XBD=1478 XHG=1370 YBD=2030 YHG=1998>there " XBD=1533 XHG=1503 YBD=2029 YHG=1998>is " XBD=1834 XHG=1560 YBD=2039 YHG=1998>documentary " XBD=2038 XHG=1859 YBD=2029 YHG=1997>evidence " XBD=2102 XHG=2063 YBD=2029 YHG=1998>of " XBD=2252 XHG=2127 YBD=2029 YHG=1998>active " XBD=2548 XHG=2275 YBD=2029 YHG=1996>immunisation " XBD=1464 XHG=1370 YBD=2075 YHG=2043>with " XBD=1631 XHG=1476 YBD=2075 YHG=2044>tetanus " XBD=1776 XHG=1643 YBD=2077 YHG=2043>toxoid " XBD=1811 XHG=1789 YBD=2074 YHG=2052>a " XBD=1940 XHG=1824 YBD=2084 YHG=2043>single " XBD=2042 XHG=1953 YBD=2075 YHG=2044>dose " XBD=2094 XHG=2055 YBD=2074 YHG=2043>of " XBD=2296 XHG=2106 YBD=2075 YHG=2043>antitoxin " XBD=2339 XHG=2308 YBD=2074 YHG=2043>is " XBD=2548 XHG=2352 YBD=2079 YHG=2041>sufficient; " XBD=1570 XHG=1373 YBD=2118 YHG=2087>otherwise " XBD=1660 XHG=1584 YBD=2119 YHG=2089>two " XBD=1822 XHG=1674 YBD=2118 YHG=2087>further " XBD=1944 XHG=1837 YBD=2119 YHG=2088>doses " XBD=1999 XHG=1961 YBD=2118 YHG=2088>of " XBD=2108 XHG=2016 YBD=2119 YHG=2089>3000 " XBD=2225 XHG=2123 YBD=2119 YHG=2088>units " XBD=2374 XHG=2241 YBD=2118 YHG=2087>should " XBD=2435 XHG=2388 YBD=2118 YHG=2087>be " XBD=2549 XHG=2448 YBD=2126 YHG=2086>given " XBD=1415 XHG=1374 YBD=2163 YHG=2134>at " XBD=1579 XHG=1433 YBD=2171 YHG=2131>weekly " XBD=1789 XHG=1595 YBD=2163 YHG=2131>intervals. SURFACE FREEZING FOR DEEP PAIN " XBD=1512 XHG=1426 YBD=2300 YHG=2272>THE " XBD=1644 XHG=1530 YBD=2301 YHG=2272>views " XBD=1705 XHG=1663 YBD=2301 YHG=2272>of " XBD=1873 XHG=1720 YBD=2301 YHG=2271>Leriche " XBD=1942 XHG=1892 YBD=2301 YHG=2280>on " XBD=2024 XHG=1960 YBD=2301 YHG=2272>the " XBD=2154 XHG=2043 YBD=2301 YHG=2272>value " XBD=2215 XHG=2173 YBD=2301 YHG=2271>of " XBD=2325 XHG=2228 YBD=2301 YHG=2272>local " XBD=2553 XHG=2342 YBD=2301 YHG=2270>anaesthesia. " XBD=1416 XHG=1376 YBD=2340 YHG=2311>in " XBD=1667 XHG=1449 YBD=2349 YHG=2311>promoting " XBD=1877 XHG=1698 YBD=2347 YHG=2320>recovery " XBD=2008 XHG=1909 YBD=2340 YHG=2311>from " XBD=2174 XHG=2041 YBD=2349 YHG=2311>simple " XBD=2453 XHG=2206 YBD=2348 YHG=2312>ligamentous " XBD=2552 XHG=2485 YBD=2340 YHG=2310>and " XBD=1567 XHG=1376 YBD=2380 YHG=2351>muscular " XBD=1742 XHG=1587 YBD=2387 YHG=2351>injuries " XBD=1825 XHG=1762 YBD=2380 YHG=2360>are " XBD=1929 XHG=1845 YBD=2380 YHG=2360>now " XBD=2086 XHG=1950 YBD=2388 YHG=2351>widely " XBD=2298 XHG=2107 YBD=2387 YHG=2351>accepted. " XBD=2427 XHG=2350 YBD=2380 YHG=2351>The " XBD=2552 XHG=2447 YBD=2380 YHG=2350>aboli- " XBD=1461 XHG=1377 YBD=2419 YHG=2391>tion " XBD=1531 XHG=1488 YBD=2419 YHG=2390>of " XBD=1716 XHG=1554 YBD=2420 YHG=2400>nervous " XBD=1921 XHG=1743 YBD=2427 YHG=2391>impulses " XBD=2047 XHG=1947 YBD=2420 YHG=2391>from " XBD=2139 XHG=2073 YBD=2420 YHG=2391>the " XBD=2351 XHG=2167 YBD=2427 YHG=2390>damaged " XBD=2554 XHG=2378 YBD=2420 YHG=2390>structure " XBD=1586 XHG=1377 YBD=2466 YHG=2431>interrupts " XBD=1694 XHG=1629 YBD=2459 YHG=2430>the " XBD=1870 XHG=1726 YBD=2459 YHG=2430>vicious " XBD=2011 XHG=1904 YBD=2459 YHG=2430>circle " XBD=2086 XHG=2044 YBD=2459 YHG=2430>of " XBD=2235 XHG=2122 YBD=2459 YHG=2430>reflex " XBD=2551 XHG=2267 YBD=2467 YHG=2430>muscle-spasm, " XBD=1676 XHG=1378 YBD=2499 YHG=2469>vasodilatation " XBD=1782 XHG=1706 YBD=2498 YHG=2469>and " XBD=1974 XHG=1814 YBD=2505 YHG=2470>oedema, " XBD=2082 XHG=2005 YBD=2499 YHG=2470>and " XBD=2335 XHG=2112 YBD=2499 YHG=2470>accelerates " XBD=2491 XHG=2365 YBD=2499 YHG=2470>return " XBD=2556 XHG=2518 YBD=2499 YHG=2471>to " XBD=1525 XHG=1378 YBD=2538 YHG=2509>normal " XBD=1729 XHG=1543 YBD=2538 YHG=2509>function. " XBD=1869 XHG=1781 YBD=2539 YHG=2509>Two " XBD=2025 XHG=1889 YBD=2546 YHG=2519>papers " XBD=2084 XHG=2044 YBD=2538 YHG=2509>in " XBD=2180 XHG=2103 YBD=2538 YHG=2509>this " XBD=2296 XHG=2199 YBD=2539 YHG=2510>issue " XBD=2479 XHG=2317 YBD=2539 YHG=2510>describe " XBD=2557 XHG=2498 YBD=2539 YHG=2509>the " XBD=1539 XHG=1378 YBD=2578 YHG=2549>benefits " XBD=1608 XHG=1565 YBD=2578 YHG=2549>of " XBD=1793 XHG=1629 YBD=2586 YHG=2549>freezing " XBD=1884 XHG=1818 YBD=2578 YHG=2549>the " XBD=1995 XHG=1910 YBD=2579 YHG=2549>skin " XBD=2113 XHG=2019 YBD=2579 YHG=2549>with " XBD=2244 XHG=2139 YBD=2585 YHG=2549>ethyl " XBD=2433 XHG=2271 YBD=2579 YHG=2549>chloride " XBD=2556 XHG=2457 YBD=2579 YHG=2549>when " XBD=1529 XHG=1379 YBD=2625 YHG=2589>dealing " XBD=1647 XHG=1552 YBD=2618 YHG=2589>with " XBD=1896 XHG=1672 YBD=2626 YHG=2589>underlying " XBD=2068 XHG=1921 YBD=2626 YHG=2589>painful " XBD=2228 XHG=2093 YBD=2618 YHG=2589>lesions " XBD=2297 XHG=2255 YBD=2618 YHG=2588>of " XBD=2395 XHG=2319 YBD=2618 YHG=2589>soft " XBD=2556 XHG=2419 YBD=2623 YHG=2589>tissues, " XBD=1640 XHG=1378 YBD=2665 YHG=2628>periarticular " XBD=1870 XHG=1664 YBD=2658 YHG=2629>structures " XBD=1936 XHG=1895 YBD=2657 YHG=2638>or " XBD=2055 XHG=1961 YBD=2658 YHG=2638>even " XBD=2228 XHG=2078 YBD=2658 YHG=2628>chronic " XBD=2351 XHG=2252 YBD=2665 YHG=2628>joint " XBD=2556 XHG=2373 YBD=2658 YHG=2629>affections " XBD=1455 XHG=1378 YBD=2697 YHG=2669>and " XBD=1664 XHG=1467 YBD=2698 YHG=2669>fractures. " XBD=1848 XHG=1715 YBD=2705 YHG=2668>Henry " XBD=2046 XHG=1859 YBD=2698 YHG=2668>describes " XBD=2218 XHG=2058 YBD=2705 YHG=2668>striking " XBD=2336 XHG=2228 YBD=2697 YHG=2668>relief " XBD=2380 XHG=2342 YBD=2698 YHG=2668>in " XBD=2411 XHG=2389 YBD=2698 YHG=2679>a " XBD=2558 XHG=2420 YBD=2705 YHG=2669>variety " XBD=1424 XHG=1380 YBD=2738 YHG=2708>of " XBD=1566 XHG=1451 YBD=2743 YHG=2717>cases, " XBD=1707 XHG=1597 YBD=2738 YHG=2708>while " XBD=1935 XHG=1737 YBD=2738 YHG=2707>McIntosh " XBD=2042 XHG=1966 YBD=2737 YHG=2708>and " XBD=2209 XHG=2072 YBD=2743 YHG=2708>Petrie, " XBD=2389 XHG=2240 YBD=2746 YHG=2708>writing " XBD=2511 XHG=2418 YBD=2738 YHG=2708>from " XBD=2559 XHG=2538 YBD=2737 YHG=2717>a " XBD=1577 XHG=1382 YBD=2778 YHG=2747>Canadian " XBD=1767 XHG=1601 YBD=2785 YHG=2748>hospital " XBD=1833 XHG=1793 YBD=2777 YHG=2748>in " XBD=2021 XHG=1858 YBD=2783 YHG=2747>Britain, " XBD=2178 XHG=2048 YBD=2777 YHG=2747>record " XBD=2347 XHG=2204 YBD=2777 YHG=2747>similar " XBD=2502 XHG=2371 YBD=2778 YHG=2749>results " XBD=2559 XHG=2524 YBD=2778 YHG=2749>in " XBD=1505 XHG=1380 YBD=2817 YHG=2787>minor " XBD=1698 XHG=1531 YBD=2824 YHG=2788>injuries, " XBD=1974 XHG=1727 YBD=2824 YHG=2788>particularly " XBD=2145 XHG=1999 YBD=2817 YHG=2787>around " XBD=2237 XHG=2172 YBD=2817 YHG=2788>the " XBD=2499 XHG=2266 YBD=2825 YHG=2787>ankle-joint, " XBD=2559 XHG=2523 YBD=2817 YHG=2788>in " XBD=1547 XHG=1381 YBD=2857 YHG=2827>soldiers. " XBD=1719 XHG=1600 YBD=2856 YHG=2827>There " XBD=1766 XHG=1735 YBD=2856 YHG=2827>is " XBD=1832 XHG=1783 YBD=2856 YHG=2837>no " XBD=1972 XHG=1851 YBD=2856 YHG=2827>doubt " XBD=2076 XHG=1988 YBD=2856 YHG=2827>that " XBD=2158 XHG=2092 YBD=2856 YHG=2827>the " XBD=2332 XHG=2176 YBD=2856 YHG=2827>method " XBD=2478 XHG=2349 YBD=2863 YHG=2828>works, " XBD=2560 XHG=2496 YBD=2857 YHG=2828>but " XBD=1648 XHG=1382 YBD=2903 YHG=2866>explanations " XBD=1716 XHG=1672 YBD=2895 YHG=2866>of " XBD=1786 XHG=1736 YBD=2895 YHG=2866>its " XBD=1940 XHG=1811 YBD=2895 YHG=2867>action " XBD=2028 XHG=1965 YBD=2895 YHG=2875>are " XBD=2212 XHG=2051 YBD=2905 YHG=2866>lacking. " XBD=2395 XHG=2264 YBD=2904 YHG=2867>Henry " XBD=2558 XHG=2420 YBD=2897 YHG=2867>demon- " XBD=1529 XHG=1383 YBD=2935 YHG=2902>strated " XBD=1604 XHG=1551 YBD=2943 YHG=2906>by " XBD=1809 XHG=1625 YBD=2942 YHG=2906>inserting " XBD=1853 XHG=1830 YBD=2935 YHG=2915>a " XBD=2144 XHG=1874 YBD=2935 YHG=2906>thermometer " XBD=2246 XHG=2164 YBD=2935 YHG=2906>into " XBD=2334 XHG=2269 YBD=2936 YHG=2907>the " XBD=2462 XHG=2356 YBD=2943 YHG=2907>thigh " XBD=2562 XHG=2483 YBD=2936 YHG=2908>that " XBD=1449 XHG=1383 YBD=2975 YHG=2945>the " XBD=1616 XHG=1464 YBD=2982 YHG=2945>chilling " XBD=1719 XHG=1630 YBD=2975 YHG=2946>does " XBD=1802 XHG=1733 YBD=2974 YHG=2946>not " XBD=1927 XHG=1815 YBD=2974 YHG=2946>reach " XBD=2035 XHG=1941 YBD=2982 YHG=2945>deep " XBD=2269 XHG=2050 YBD=2980 YHG=2945>structures, " XBD=2360 XHG=2283 YBD=2975 YHG=2946>and " XBD=2430 XHG=2372 YBD=2975 YHG=2946>his " XBD=2560 XHG=2442 YBD=2983 YHG=2947>happy " XBD=1604 XHG=1384 YBD=3021 YHG=2985>experience " XBD=1722 XHG=1627 YBD=3014 YHG=2985>with " XBD=1768 XHG=1745 YBD=3014 YHG=2994>a " XBD=2014 XHG=1794 YBD=3021 YHG=2985>colleague’s " XBD=2262 XHG=2040 YBD=3014 YHG=2984>dachshund " XBD=2404 XHG=2287 YBD=3014 YHG=2994>seems " XBD=2468 XHG=2428 YBD=3015 YHG=2986>to " XBD=2560 XHG=2491 YBD=3015 YHG=2986>rule " XBD=1454 XHG=1385 YBD=3053 YHG=3025>out " XBD=1550 XHG=1485 YBD=3053 YHG=3025>the " XBD=1744 XHG=1582 YBD=3053 YHG=3024>element " XBD=1818 XHG=1775 YBD=3053 YHG=3024>of " XBD=2071 XHG=1844 YBD=3061 YHG=3024>suggestion. " XBD=2202 XHG=2124 YBD=3053 YHG=3025>The " XBD=2316 XHG=2231 YBD=3054 YHG=3034>now " XBD=2558 XHG=2348 YBD=3055 YHG=3024>established " XBD=1489 XHG=1384 YBD=3093 YHG=3064>work " XBD=1547 XHG=1505 YBD=3093 YHG=3064>of Kellgren " XBD=1830 XHG=1753 YBD=3092 YHG=3064>2 on " XBD=1935 XHG=1843 YBD=3100 YHG=3064>pain " XBD=2111 XHG=1948 YBD=3093 YHG=3063>referred " XBD=2301 XHG=2127 YBD=3101 YHG=3063>diffusely " XBD=2412 XHG=2315 YBD=3093 YHG=3063>from " XBD=2561 XHG=2426 YBD=3094 YHG=3073>muscu- " XBD=1443 XHG=1386 YBD=3132 YHG=3103>lar " XBD=1540 XHG=1464 YBD=3133 YHG=3104>and " XBD=1813 XHG=1561 YBD=3140 YHG=3103>ligamentous " XBD=1908 XHG=1833 YBD=3132 YHG=3103>foci " XBD=2048 XHG=1929 YBD=3132 YHG=3112>seems " XBD=2251 XHG=2069 YBD=3133 YHG=3103>relevant. " XBD=2342 XHG=2303 YBD=3133 YHG=3104>It " XBD=2392 XHG=2361 YBD=3133 YHG=3104>is " XBD=2562 XHG=2413 YBD=3140 YHG=3104>possible " XBD=1475 XHG=1387 YBD=3172 YHG=3143>that " XBD=1824 XHG=1497 YBD=3172 YHG=3143>ansesthetisation " XBD=1889 XHG=1845 YBD=3172 YHG=3142>of " XBD=1971 XHG=1905 YBD=3172 YHG=3143>the " XBD=2203 XHG=1992 YBD=3180 YHG=3143>superficial " XBD=2311 XHG=2223 YBD=3172 YHG=3152>area " XBD=2374 XHG=2332 YBD=3173 YHG=3143>of " XBD=2563 XHG=2390 YBD=3172 YHG=3143>reference " XBD=1441 XHG=1387 YBD=3220 YHG=3182>by " XBD=1632 XHG=1468 YBD=3220 YHG=3183>freezing " XBD=1750 XHG=1660 YBD=3219 YHG=3192>may " XBD=1925 XHG=1778 YBD=3212 YHG=3182>abolish " XBD=2019 XHG=1953 YBD=3212 YHG=3183>the " XBD=2149 XHG=2047 YBD=3220 YHG=3183>pain, " XBD=2221 XHG=2180 YBD=3212 YHG=3192>as " XBD=2288 XHG=2249 YBD=3212 YHG=3183>in " XBD=2381 XHG=2316 YBD=3213 YHG=3183>the " XBD=2564 XHG=2409 YBD=3212 YHG=3182>classical " XBD=1536 XHG=1388 YBD=3258 YHG=3223>though " XBD=1737 XHG=1559 YBD=3259 YHG=3222>disputed " XBD=2013 XHG=1760 YBD=3258 YHG=3223>experiments " XBD=2075 XHG=2036 YBD=3251 YHG=3223>in " XBD=2220 XHG=2097 YBD=3251 YHG=3222>which " XBD=2403 XHG=2242 YBD=3252 YHG=3222>referred " XBD=2510 XHG=2425 YBD=3258 YHG=3222>pain " XBD=2568 XHG=2531 YBD=3251 YHG=3221>of " XBD=1692 XHG=1390 YBD=3297 YHG=3261>diaphragmatic " XBD=1842 XHG=1721 YBD=3297 YHG=3261>origin " XBD=1942 XHG=1865 YBD=3291 YHG=3270>was " XBD=2162 XHG=1968 YBD=3290 YHG=3261>abolished " XBD=2239 XHG=2187 YBD=3298 YHG=3262>by " XBD=2484 XHG=2263 YBD=3296 YHG=3261>infiltrating " XBD=2564 XHG=2506 YBD=3289 YHG=3261>the " XBD=1475 XHG=1389 YBD=3330 YHG=3300>skin " XBD=1536 XHG=1493 YBD=3330 YHG=3300>of " XBD=1616 XHG=1551 YBD=3330 YHG=3301>the " XBD=1812 XHG=1635 YBD=3331 YHG=3300>shoulder " XBD=1923 XHG=1828 YBD=3330 YHG=3300>with " XBD=2128 XHG=1940 YBD=3337 YHG=3301>procaine. " XBD=2259 XHG=2179 YBD=3330 YHG=3301>But " XBD=2352 XHG=2276 YBD=3330 YHG=3301>this " XBD=2400 XHG=2369 YBD=3329 YHG=3300>is " XBD=2566 XHG=2419 YBD=3328 YHG=3300>another " XBD=1433 XHG=1389 YBD=3370 YHG=3340>of " XBD=1566 XHG=1457 YBD=3370 YHG=3340>those " XBD=1861 XHG=1594 YBD=3370 YHG=3339>well-founded " XBD=2037 XHG=1890 YBD=3369 YHG=3340>clinical " XBD=2326 XHG=2064 YBD=3370 YHG=3340>observations " XBD=2472 XHG=2353 YBD=3370 YHG=3338>which " XBD=2567 XHG=2498 YBD=3367 YHG=3337>still " XBD=1505 XHG=1389 YBD=3409 YHG=3380>await " XBD=1590 XHG=1524 YBD=3409 YHG=3380>the " XBD=1840 XHG=1609 YBD=3409 YHG=3379>elucidation " XBD=1901 XHG=1858 YBD=3409 YHG=3380>of " XBD=2058 XHG=1917 YBD=3409 YHG=3380>careful " XBD=2257 XHG=2077 YBD=3410 YHG=3380>scientific " XBD=2455 XHG=2276 YBD=3409 YHG=3378>research. 1. Army med. Direct. Bull. July, 1942, p. 3. 2. Kellgren, H. J. Clin. Sci. 1938, 3, 174.

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" XBD=175 XHG=91 YBD=215 YHG=184>well " XBD=234 XHG=193 YBD=215 YHG=194>as " XBD=350 XHG=251 YBD=215 YHG=185>from " XBD=516 XHG=369 YBD=215 YHG=180>clinical " XBD=753 XHG=534 YBD=224 YHG=184>experience " XBD=800 XHG=769 YBD=215 YHG=184>it " XBD=848 XHG=816 YBD=215 YHG=184>is " XBD=946 XHG=867 YBD=215 YHG=185>safe " XBD=1005 XHG=964 YBD=215 YHG=186>to " XBD=1092 XHG=1025 YBD=224 YHG=194>say " XBD=1198 XHG=1111 YBD=215 YHG=185>that " XBD=1284 XHG=1216 YBD=216 YHG=185>the" XBD=304 XHG=92 YBD=267 YHG=227>possession " XBD=358 XHG=319 YBD=259 YHG=228>of " XBD=422 XHG=372 YBD=259 YHG=238>an " XBD=545 XHG=437 YBD=259 YHG=237>arcus " XBD=685 XHG=561 YBD=259 YHG=227>senilis " XBD=790 XHG=700 YBD=259 YHG=228>does " XBD=872 XHG=804 YBD=258 YHG=228>not " XBD=998 XHG=888 YBD=259 YHG=238>mean " XBD=1063 XHG=1013 YBD=259 YHG=228>its " XBD=1202 XHG=1078 YBD=259 YHG=237>owner " XBD=1284 XHG=1215 YBD=259 YHG=228>has" XBD=266 XHG=91 YBD=303 YHG=272>vascular " XBD=438 XHG=284 YBD=304 YHG=272>disease.

VENOUS OBSTRUCTION IN VOLKMANN’SCONTRACTURE

" XBD=280 XHG=147 YBD=475 YHG=445>THOSE " XBD=386 XHG=302 YBD=475 YHG=445>who " XBD=507 XHG=408 YBD=476 YHG=445>have " XBD=616 XHG=528 YBD=475 YHG=445>held " XBD=725 XHG=637 YBD=475 YHG=445>that " XBD=890 XHG=746 YBD=475 YHG=454>venous " XBD=1149 XHG=912 YBD=476 YHG=445>obstruction " XBD=1201 XHG=1170 YBD=476 YHG=446>is " XBD=1288 XHG=1222 YBD=476 YHG=446>the

" XBD=197 XHG=97 YBD=519 YHG=490>most " XBD=428 XHG=217 YBD=528 YHG=488>important " XBD=571 XHG=447 YBD=520 YHG=489>factor " XBD=630 XHG=590 YBD=519 YHG=489>in " XBD=716 XHG=650 YBD=519 YHG=489>the " XBD=963 XHG=735 YBD=528 YHG=488>production " XBD=1021 XHG=984 YBD=519 YHG=489>of " XBD=1289 XHG=1042 YBD=521 YHG=490>Volkmann’s" XBD=285 XHG=96 YBD=563 YHG=532>ischaemic " XBD=546 XHG=306 YBD=564 YHG=535>contracture " XBD=666 XHG=567 YBD=563 YHG=533>have " XBD=804 XHG=687 YBD=563 YHG=533>based " XBD=924 XHG=825 YBD=563 YHG=532>their " XBD=1058 XHG=944 YBD=564 YHG=532>belief " XBD=1219 XHG=1077 YBD=574 YHG=534>largely " XBD=1327 XHG=1241 YBD=564 YHG=536>on" XBD=121 XHG=98 YBD=606 YHG=585>a " XBD=334 XHG=147 YBD=616 YHG=577>supposed " XBD=498 XHG=359 YBD=616 YHG=576>special " XBD=792 XHG=521 YBD=615 YHG=576>vulnerability " XBD=856 XHG=818 YBD=606 YHG=576>of " XBD=945 XHG=880 YBD=606 YHG=576>the " XBD=1290 XHG=971 YBD=608 YHG=578>communication" XBD=269 XHG=97 YBD=651 YHG=619>between " XBD=351 XHG=285 YBD=651 YHG=620>the " XBD=581 XHG=370 YBD=659 YHG=620>superficial " XBD=675 XHG=599 YBD=650 YHG=620>and " XBD=785 XHG=693 YBD=659 YHG=620>deep " XBD=947 XHG=804 YBD=650 YHG=629>venous " XBD=1127 XHG=966 YBD=660 YHG=622>systems " XBD=1290 XHG=1145 YBD=652 YHG=621>around" XBD=165 XHG=98 YBD=695 YHG=663>the " XBD=324 XHG=194 YBD=695 YHG=664>elbow. " XBD=424 XHG=378 YBD=699 YHG=664>If, " XBD=496 XHG=455 YBD=694 YHG=673>as " XBD=594 XHG=524 YBD=694 YHG=664>has " XBD=718 XHG=622 YBD=694 YHG=664>been " XBD=846 XHG=746 YBD=699 YHG=663>held, " XBD=942 XHG=875 YBD=694 YHG=664>the " XBD=1291 XHG=972 YBD=695 YHG=665>communication" XBD=267 XHG=99 YBD=748 YHG=707>depends " XBD=344 XHG=296 YBD=738 YHG=717>on " XBD=444 XHG=374 YBD=738 YHG=717>one " XBD=583 XHG=473 YBD=738 YHG=707>small " XBD=754 XHG=611 YBD=738 YHG=717>venous " XBD=944 XHG=784 YBD=739 YHG=708>channel " XBD=1230 XHG=966 YBD=749 YHG=709>lying deeply " XBD=1291 XHG=1251 YBD=738 YHG=709>in" XBD=166 XHG=98 YBD=782 YHG=752>the " XBD=420 XHG=185 YBD=783 YHG=751>antecubital " XBD=551 XHG=438 YBD=788 YHG=752>fossa, " XBD=600 XHG=569 YBD=782 YHG=752>it " XBD=651 XHG=619 YBD=782 YHG=751>is " XBD=760 XHG=671 YBD=792 YHG=761>easy " XBD=821 XHG=779 YBD=783 YHG=754>to " XBD=1017 XHG=841 YBD=783 YHG=752>visualise " XBD=1085 XHG=1035 YBD=783 YHG=753>its " XBD=1291 XHG=1105 YBD=792 YHG=752>complete" XBD=354 XHG=99 YBD=835 YHG=795>interruption " XBD=424 XHG=372 YBD=835 YHG=796>by " XBD=508 XHG=442 YBD=826 YHG=796>the " XBD=780 XHG=528 YBD=835 YHG=796>compression " XBD=838 XHG=800 YBD=827 YHG=796>of " XBD=1007 XHG=856 YBD=828 YHG=796>swollen " XBD=1101 XHG=1025 YBD=827 YHG=797>and " XBD=1293 XHG=1119 YBD=835 YHG=796>bleeding" XBD=249 XHG=101 YBD=876 YHG=839>tissues, " XBD=360 XHG=285 YBD=870 YHG=840>and " XBD=639 XHG=392 YBD=880 YHG=840>particularly " XBD=724 XHG=672 YBD=880 YHG=840>by " XBD=779 XHG=757 YBD=871 YHG=850>a " XBD=1018 XHG=816 YBD=872 YHG=841>subfascial " XBD=1290 XHG=1050 YBD=871 YHG=841>haematoma." XBD=150 XHG=103 YBD=914 YHG=883>In " XBD=195 XHG=173 YBD=914 YHG=893>a " XBD=330 XHG=220 YBD=915 YHG=884>series " XBD=394 XHG=355 YBD=914 YHG=884>of " XBD=559 XHG=418 YBD=915 YHG=884>careful " XBD=813 XHG=583 YBD=916 YHG=885>anatomical " XBD=979 XHG=837 YBD=916 YHG=884>studies Horwitz " XBD=1293 XHG=1188 YBD=915 YHG=884>has" XBD=389 XHG=103 YBD=960 YHG=928>demonstrated " XBD=491 XHG=425 YBD=960 YHG=929>the " XBD=737 XHG=527 YBD=961 YHG=930>variations " XBD=861 XHG=773 YBD=961 YHG=930>that " XBD=968 XHG=898 YBD=960 YHG=939>can " XBD=1117 XHG=1006 YBD=961 YHG=939>occur " XBD=1192 XHG=1152 YBD=959 YHG=929>in " XBD=1294 XHG=1228 YBD=959 YHG=928>the" XBD=443 XHG=104 YBD=1005 YHG=973>communications " XBD=660 XHG=488 YBD=1005 YHG=974>between " XBD=772 XHG=705 YBD=1005 YHG=975>the " XBD=913 XHG=819 YBD=1013 YHG=975>deep " XBD=1037 XHG=961 YBD=1004 YHG=974>and " XBD=1296 XHG=1083 YBD=1013 YHG=972>superficial" XBD=247 XHG=103 YBD=1048 YHG=1027>venous " XBD=428 XHG=266 YBD=1058 YHG=1019>systems " XBD=486 XHG=446 YBD=1049 YHG=1019>at " XBD=571 XHG=505 YBD=1049 YHG=1018>the " XBD=720 XHG=590 YBD=1053 YHG=1019>elbow. " XBD=832 XHG=774 YBD=1048 YHG=1019>He " XBD=918 XHG=848 YBD=1048 YHG=1018>has " XBD=1067 XHG=936 YBD=1049 YHG=1017>shown " XBD=1171 XHG=1084 YBD=1049 YHG=1017>that " XBD=1295 XHG=1189 YBD=1047 YHG=1017>there" XBD=168 XHG=104 YBD=1092 YHG=1071>are " XBD=293 XHG=186 YBD=1093 YHG=1062>three " XBD=468 XHG=313 YBD=1093 YHG=1062>distinct " XBD=682 XHG=489 YBD=1093 YHG=1062>collateral " XBD=806 XHG=699 YBD=1094 YHG=1062>veins " XBD=867 XHG=827 YBD=1092 YHG=1071>or " XBD=1030 XHG=887 YBD=1092 YHG=1071>venous " XBD=1237 XHG=1049 YBD=1092 YHG=1061>networks " XBD=1296 XHG=1256 YBD=1091 YHG=1061>in" XBD=278 XHG=105 YBD=1137 YHG=1106>addition " XBD=359 XHG=317 YBD=1137 YHG=1108>to " XBD=465 XHG=399 YBD=1137 YHG=1107>the " XBD=684 XHG=506 YBD=1137 YHG=1106>so-called " XBD=1044 XHG=724 YBD=1145 YHG=1105>communicating " XBD=1182 XHG=1083 YBD=1136 YHG=1105>vein. " XBD=1294 XHG=1234 YBD=1144 YHG=1105>By" XBD=288 XHG=104 YBD=1191 YHG=1150>injecting " XBD=540 XHG=308 YBD=1191 YHG=1151>radiopaque " XBD=729 XHG=562 YBD=1181 YHG=1150>medium " XBD=857 XHG=752 YBD=1192 YHG=1149>(30% " XBD=1030 XHG=883 YBD=1180 YHG=1149>sodium " XBD=1192 XHG=1052 YBD=1188 YHG=1149>iodide) " XBD=1296 XHG=1214 YBD=1180 YHG=1149>into" XBD=172 XHG=72 YBD=1226 YHG=1189>the " XBD=311 XHG=191 YBD=1235 YHG=1205>upper " XBD=536 XHG=331 YBD=1235 YHG=1195>extremity " XBD=595 XHG=556 YBD=1225 YHG=1195>of " XBD=661 XHG=618 YBD=1225 YHG=1196>10 " XBD=873 XHG=671 YBD=1230 YHG=1187>cadavers, " XBD=917 XHG=895 YBD=1224 YHG=1203>a " XBD=1048 XHG=937 YBD=1224 YHG=1194>series " XBD=1106 XHG=1069 YBD=1224 YHG=1194>of " XBD=1298 XHG=1126 YBD=1233 YHG=1193>complex" XBD=297 XHG=106 YBD=1271 YHG=1240>networks " XBD=413 XHG=335 YBD=1270 YHG=1249>was " XBD=739 XHG=453 YBD=1270 YHG=1239>demonstrated " XBD=990 XHG=777 YBD=1269 YHG=1237>additional " XBD=1069 XHG=1027 YBD=1268 YHG=1239>to " XBD=1174 XHG=1108 YBD=1268 YHG=1238>the " XBD=1299 XHG=1213 YBD=1268 YHG=1238>four" XBD=445 XHG=107 YBD=1315 YHG=1284>communications " XBD=595 XHG=471 YBD=1314 YHG=1283>which " XBD=717 XHG=620 YBD=1313 YHG=1288>were " XBD=844 XHG=743 YBD=1323 YHG=1283>large " XBD=1019 XHG=870 YBD=1322 YHG=1282>enough " XBD=1086 XHG=1046 YBD=1313 YHG=1284>to " XBD=1161 XHG=1113 YBD=1313 YHG=1282>be " XBD=1299 XHG=1188 YBD=1313 YHG=1282>made" XBD=177 XHG=110 YBD=1359 YHG=1329>out " XBD=260 XHG=208 YBD=1368 YHG=1328>by " XBD=393 XHG=291 YBD=1368 YHG=1337>gross " XBD=638 XHG=425 YBD=1358 YHG=1327>dissection. " XBD=769 XHG=690 YBD=1358 YHG=1327>The " XBD=948 XHG=800 YBD=1357 YHG=1326>sodium " XBD=1104 XHG=978 YBD=1357 YHG=1326>iodide " XBD=1299 XHG=1134 YBD=1366 YHG=1326>injected" XBD=189 XHG=107 YBD=1403 YHG=1372>into " XBD=284 XHG=214 YBD=1403 YHG=1382>one " XBD=345 XHG=306 YBD=1403 YHG=1372>of " XBD=432 XHG=366 YBD=1402 YHG=1372>the " XBD=574 XHG=453 YBD=1402 YHG=1371>radial " XBD=638 XHG=597 YBD=1401 YHG=1380>or " XBD=768 XHG=659 YBD=1402 YHG=1371>ulnar " XBD=896 XHG=790 YBD=1402 YHG=1371>veins " XBD=1107 XHG=919 YBD=1411 YHG=1372>appeared " XBD=1298 XHG=1128 YBD=1402 YHG=1371>immedi-" XBD=213 XHG=109 YBD=1456 YHG=1417>ately " XBD=276 XHG=236 YBD=1446 YHG=1417>in " XBD=365 XHG=299 YBD=1447 YHG=1416>the " XBD=471 XHG=390 YBD=1446 YHG=1425>arm " XBD=617 XHG=496 YBD=1447 YHG=1416>above " XBD=707 XHG=642 YBD=1446 YHG=1416>the " XBD=803 XHG=733 YBD=1446 YHG=1416>site " XBD=867 XHG=828 YBD=1446 YHG=1416>of " XBD=1060 XHG=890 YBD=1456 YHG=1415>ligation. " XBD=1300 XHG=1112 YBD=1455 YHG=1415>Injection" XBD=186 XHG=108 YBD=1492 YHG=1470>was " XBD=391 XHG=200 YBD=1501 YHG=1460>practised " XBD=475 XHG=406 YBD=1490 YHG=1461>not " XBD=582 XHG=493 YBD=1500 YHG=1460>only " XBD=690 XHG=597 YBD=1491 YHG=1460>with " XBD=757 XHG=708 YBD=1491 YHG=1470>an " XBD=895 XHG=773 YBD=1491 YHG=1460>intact " XBD=1055 XHG=911 YBD=1491 YHG=1470>venous " XBD=1214 XHG=1072 YBD=1500 YHG=1462>system " XBD=1301 XHG=1230 YBD=1492 YHG=1460>but" XBD=189 XHG=110 YBD=1536 YHG=1505>also " XBD=307 XHG=209 YBD=1536 YHG=1505>after " XBD=483 XHG=324 YBD=1545 YHG=1505>ligation " XBD=541 XHG=503 YBD=1536 YHG=1505>of " XBD=625 XHG=559 YBD=1536 YHG=1505>the " XBD=966 XHG=645 YBD=1546 YHG=1505>communicating " XBD=1072 XHG=984 YBD=1536 YHG=1505>vein " XBD=1168 XHG=1089 YBD=1545 YHG=1505>just " XBD=1303 XHG=1189 YBD=1536 YHG=1505>distal" XBD=152 XHG=111 YBD=1580 YHG=1550>to " XBD=233 XHG=182 YBD=1580 YHG=1550>its " XBD=509 XHG=263 YBD=1580 YHG=1549>termination " XBD=579 XHG=540 YBD=1580 YHG=1550>in " XBD=676 XHG=609 YBD=1580 YHG=1550>the " XBD=874 XHG=706 YBD=1589 YHG=1549>cephalic " XBD=946 XHG=906 YBD=1580 YHG=1559>or " XBD=1129 XHG=978 YBD=1580 YHG=1549>median " XBD=1304 XHG=1160 YBD=1581 YHG=1550>cubital" XBD=211 XHG=111 YBD=1631 YHG=1594>vein, " XBD=300 XHG=224 YBD=1625 YHG=1594>and " XBD=351 XHG=313 YBD=1625 YHG=1594>of " XBD=432 XHG=366 YBD=1624 YHG=1594>the " XBD=615 XHG=446 YBD=1625 YHG=1594>brachial " XBD=735 XHG=629 YBD=1625 YHG=1594>veins " XBD=831 XHG=751 YBD=1634 YHG=1594>just " XBD=968 XHG=847 YBD=1626 YHG=1594>above " XBD=1046 XHG=981 YBD=1625 YHG=1595>the " XBD=1132 XHG=1060 YBD=1625 YHG=1594>site " XBD=1186 XHG=1148 YBD=1625 YHG=1595>of |>" XBD=1303 XHG=1206 YBD=1628 YHG=1594>their" XBD=331 XHG=112 YBD=1670 YHG=1638>formation. " XBD=461 XHG=382 YBD=1669 YHG=1639>The " XBD=675 XHG=497 YBD=1675 YHG=1639>solution, " XBD=858 XHG=712 YBD=1679 YHG=1638>despite " XBD=999 XHG=893 YBD=1670 YHG=1639>these " XBD=1303 XHG=1036 YBD=1675 YHG=1639>obstructions," XBD=373 XHG=112 YBD=1723 YHG=1682>immediately " XBD=552 XHG=397 YBD=1714 YHG=1683>entered " XBD=653 XHG=577 YBD=1713 YHG=1683>and " XBD=833 XHG=678 YBD=1715 YHG=1684>coursed " XBD=908 XHG=856 YBD=1723 YHG=1693>up " XBD=999 XHG=933 YBD=1714 YHG=1684>the " XBD=1104 XHG=1023 YBD=1714 YHG=1693>arm " XBD=1167 XHG=1128 YBD=1714 YHG=1683>in " XBD=1305 XHG=1192 YBD=1723 YHG=1693>every" XBD=296 XHG=113 YBD=1760 YHG=1727>instance. " XBD=495 XHG=328 YBD=1759 YHG=1727>Horwitz " XBD=706 XHG=508 YBD=1759 YHG=1727>concludes " XBD=804 XHG=717 YBD=1759 YHG=1728>that " XBD=837 XHG=816 YBD=1759 YHG=1738>a " XBD=946 XHG=848 YBD=1769 YHG=1728>good " XBD=1151 XHG=957 YBD=1759 YHG=1728>collateral " XBD=1305 XHG=1162 YBD=1760 YHG=1738>venous" XBD=336 XHG=115 YBD=1804 YHG=1773>circulation " XBD=555 XHG=368 YBD=1813 YHG=1772>normally " XBD=696 XHG=579 YBD=1803 YHG=1772>exists " XBD=766 XHG=727 YBD=1804 YHG=1772>in " XBD=864 XHG=798 YBD=1804 YHG=1774>the " XBD=1016 XHG=897 YBD=1805 YHG=1773>elbow " XBD=1188 XHG=1048 YBD=1814 YHG=1773>region, " XBD=1307 XHG=1223 YBD=1805 YHG=1773>well" XBD=312 XHG=113 YBD=1858 YHG=1818>protected |>" XBD=381 XHG=327 YBD=1859 YHG=1817>by " XBD=536 XHG=396 YBD=1848 YHG=1818>muscle " XBD=681 XHG=550 YBD=1857 YHG=1817>planes " XBD=773 XHG=697 YBD=1848 YHG=1817>and " XBD=970 XHG=798 YBD=1849 YHG=1818>external " XBD=1031 XHG=991 YBD=1849 YHG=1820>to " XBD=1123 XHG=1058 YBD=1849 YHG=1819>the " XBD=1307 XHG=1144 YBD=1849 YHG=1818>confines" XBD=157 XHG=117 YBD=1893 YHG=1862>of " XBD=247 XHG=179 YBD=1893 YHG=1862>the " XBD=508 XHG=271 YBD=1893 YHG=1862>antecubital " XBD=645 XHG=530 YBD=1893 YHG=1862>fossa. " XBD=775 XHG=696 YBD=1893 YHG=1862>The " XBD=1030 XHG=800 YBD=1894 YHG=1863>anatomical " XBD=1155 XHG=1054 YBD=1894 YHG=1863>basis " XBD=1219 XHG=1180 YBD=1893 YHG=1863>of " XBD=1308 XHG=1242 YBD=1893 YHG=1863>the" XBD=518 XHG=117 YBD=1938 YHG=1907>venous-obstruction " XBD=674 XHG=537 YBD=1947 YHG=1906>theory " XBD=733 XHG=694 YBD=1937 YHG=1907>of " XBD=1000 XHG=752 YBD=1938 YHG=1906>Volkmann’s " XBD=1259 XHG=1020 YBD=1938 YHG=1909>contracture " XBD=1310 XHG=1278 YBD=1938 YHG=1907>is" XBD=209 XHG=118 YBD=1982 YHG=1951>thus " XBD=501 XHG=240 YBD=1982 YHG=1951>undermined. " XBD=653 XHG=553 YBD=1982 YHG=1951>That " XBD=830 XHG=685 YBD=1982 YHG=1951>sudden " XBD=1135 XHG=862 YBD=1991 YHG=1952>experimental " XBD=1309 XHG=1165 YBD=1983 YHG=1961>venous" XBD=306 XHG=117 YBD=2028 YHG=1996>occlusion " XBD=416 XHG=326 YBD=2036 YHG=2006>may " XBD=602 XHG=435 YBD=2036 YHG=1996>produce " XBD=644 XHG=623 YBD=2027 YHG=2006>a " XBD=860 XHG=666 YBD=2027 YHG=1996>condition " XBD=1104 XHG=879 YBD=2037 YHG=1997>resembling " XBD=1310 XHG=1124 YBD=2028 YHG=1996>ischaemic" XBD=360 XHG=118 YBD=2072 YHG=2042>contracture " XBD=455 XHG=385 YBD=2082 YHG=2051>can " XBD=643 XHG=479 YBD=2081 YHG=2041>perhaps " XBD=715 XHG=668 YBD=2072 YHG=2041>be " XBD=940 XHG=740 YBD=2081 YHG=2040>explained " XBD=1130 XHG=964 YBD=2081 YHG=2041>through " XBD=1177 XHG=1155 YBD=2072 YHG=2051>a " XBD=1309 XHG=1201 YBD=2072 YHG=2051>vaso-" XBD=244 XHG=118 YBD=2116 YHG=2087>motor " XBD=403 XHG=276 YBD=2116 YHG=2085>reflex. " XBD=575 XHG=455 YBD=2116 YHG=2085>There " XBD=640 XHG=608 YBD=2116 YHG=2085>is " XBD=759 XHG=674 YBD=2116 YHG=2095>now " XBD=978 XHG=792 YBD=2116 YHG=2085>sufficient " XBD=1192 XHG=1012 YBD=2117 YHG=2086>evidence " XBD=1311 XHG=1225 YBD=2117 YHG=2086>that" XBD=270 XHG=117 YBD=2161 YHG=2131>trauma " XBD=335 XHG=294 YBD=2161 YHG=2131>to " XBD=410 XHG=360 YBD=2161 YHG=2139>an " XBD=562 XHG=435 YBD=2170 YHG=2131>artery " XBD=658 XHG=587 YBD=2161 YHG=2139>can " XBD=847 XHG=681 YBD=2170 YHG=2129>produce " XBD=986 XHG=870 YBD=2161 YHG=2130>reflex |>" XBD=1212 XHG=1009 YBD=2166 YHG=2130>ischemia, " XBD=1313 XHG=1237 YBD=2160 YHG=2130>and" XBD=184 XHG=116 YBD=2206 YHG=2174>the " XBD=404 XHG=207 YBD=2206 YHG=2174>otherwise " XBD=676 XHG=425 YBD=2215 YHG=2174>inexplicable " XBD=888 XHG=696 YBD=2218 YHG=2173>isohasmia " XBD=949 XHG=911 YBD=2206 YHG=2174>of " XBD=1037 XHG=971 YBD=2206 YHG=2174>the " XBD=1174 XHG=1058 YBD=2206 YHG=2175>white " XBD=1254 XHG=1194 YBD=2216 YHG=2175>leg " XBD=1314 XHG=1276 YBD=2205 YHG=2174>of" XBD=262 XHG=117 YBD=2251 YHG=2229>venous " XBD=509 XHG=278 YBD=2250 YHG=2219>thrombosis " XBD=596 XHG=526 YBD=2250 YHG=2220>has " XBD=691 XHG=613 YBD=2250 YHG=2219>also " XBD=805 XHG=709 YBD=2250 YHG=2219>been " XBD=1004 XHG=821 YBD=2260 YHG=2220>regarded " XBD=1063 XHG=1022 YBD=2251 YHG=2229>as " XBD=1259 XHG=1080 YBD=2250 YHG=2220>evidence " XBD=1316 XHG=1278 YBD=2250 YHG=2219>of" XBD=196 XHG=118 YBD=2295 YHG=2264>this " XBD=329 XHG=213 YBD=2295 YHG=2264>reflex " XBD=592 XHG=347 YBD=2295 YHG=2264>mechanism.

CHRONIC INFLAMMATION

" XBD=392 XHG=173 YBD=2429 YHG=2398>So-CALLED " XBD=562 XHG=411 YBD=2430 YHG=2399>chronic " XBD=860 XHG=577 YBD=2437 YHG=2397>inflammatory " XBD=1009 XHG=881 YBD=2434 YHG=2398>tissue, " XBD=1066 XHG=1027 YBD=2428 YHG=2398>of " XBD=1134 XHG=1085 YBD=2428 YHG=2407>no " XBD=1315 XHG=1156 YBD=2429 YHG=2398>discern-" XBD=198 XHG=96 YBD=2476 YHG=2442>ible " XBD=351 XHG=221 YBD=2483 YHG=2443>origin, " XBD=407 XHG=375 YBD=2474 YHG=2444>is " XBD=535 XHG=430 YBD=2474 YHG=2444>often " XBD=812 XHG=558 YBD=2474 YHG=2443>encountered " XBD=873 XHG=834 YBD=2472 YHG=2442>in " XBD=1039 XHG=895 YBD=2473 YHG=2442>human " XBD=1319 XHG=1061 YBD=2482 YHG=2441>pathological" XBD=310 XHG=125 YBD=2523 YHG=2487>material, " XBD=412 XHG=336 YBD=2518 YHG=2488>and " XBD=466 XHG=435 YBD=2518 YHG=2488>it " XBD=523 XHG=491 YBD=2519 YHG=2488>is " XBD=737 XHG=547 YBD=2528 YHG=2487>generally " XBD=932 XHG=757 YBD=2518 YHG=2487>assumed " XBD=1043 XHG=956 YBD=2517 YHG=2486>that " XBD=1134 XHG=1068 YBD=2517 YHG=2486>the " XBD=1318 XHG=1158 YBD=2517 YHG=2483>cause-" XBD=317 XHG=122 YBD=2563 YHG=2531>whatever " XBD=360 XHG=329 YBD=2563 YHG=2532>it " XBD=487 XHG=373 YBD=2563 YHG=2533>is-is " XBD=680 XHG=501 YBD=2563 YHG=2531>extrinsic " XBD=769 XHG=693 YBD=2563 YHG=2532>and " XBD=869 XHG=782 YBD=2563 YHG=2532>that " XBD=948 XHG=883 YBD=2562 YHG=2531>the " XBD=1076 XHG=963 YBD=2571 YHG=2532>agent " XBD=1319 XHG=1088 YBD=2570 YHG=2530>responsible" XBD=262 XHG=127 YBD=2607 YHG=2576>should " XBD=331 XHG=285 YBD=2607 YHG=2576>be " XBD=587 XHG=353 YBD=2608 YHG=2576>identifiable " XBD=648 XHG=608 YBD=2607 YHG=2576>in " XBD=736 XHG=671 YBD=2607 YHG=2577>the " XBD=1042 XHG=758 YBD=2615 YHG=2577>inflammatory " XBD=1182 XHG=1065 YBD=2606 YHG=2575>tissue " XBD=1318 XHG=1204 YBD=2606 YHG=2575>itself." XBD=315 XHG=125 YBD=2661 YHG=2620>Pullinger " XBD=413 XHG=337 YBD=2651 YHG=2621>and Pirie " XBD=681 XHG=548 YBD=2653 YHG=2622>2 have " XBD=883 XHG=702 YBD=2652 YHG=2620>obtained " XBD=1083 XHG=905 YBD=2651 YHG=2620>evidence " XBD=1146 XHG=1104 YBD=2651 YHG=2622>to " XBD=1319 XHG=1168 YBD=2660 YHG=2621>suggest" XBD=214 XHG=125 YBD=2696 YHG=2665>that " XBD=478 XHG=234 YBD=2704 YHG=2665>non-specific " XBD=651 XHG=499 YBD=2697 YHG=2666>chronic " XBD=949 XHG=672 YBD=2696 YHG=2665>inflammation " XBD=1060 XHG=972 YBD=2704 YHG=2674>may " XBD=1128 XHG=1081 YBD=2695 YHG=2665>be " XBD=1319 XHG=1148 YBD=2696 YHG=2664>intrinsic" XBD=166 XHG=127 YBD=2740 YHG=2709>in " XBD=304 XHG=185 YBD=2749 YHG=2709>origin " XBD=399 XHG=323 YBD=2740 YHG=2710>and " XBD=521 XHG=418 YBD=2740 YHG=2719>more " XBD=664 XHG=540 YBD=2741 YHG=2710>subtle " XBD=778 XHG=682 YBD=2741 YHG=2710>than " XBD=827 XHG=795 YBD=2741 YHG=2710>is " XBD=994 XHG=845 YBD=2749 YHG=2709>usually " XBD=1225 XHG=1013 YBD=2749 YHG=2708>suspected, " XBD=1320 XHG=1244 YBD=2740 YHG=2708>and" XBD=214 XHG=127 YBD=2785 YHG=2754>that " XBD=274 XHG=242 YBD=2784 YHG=2754>it " XBD=393 XHG=304 YBD=2793 YHG=2763>may " XBD=558 XHG=422 YBD=2794 YHG=2754>persist " XBD=646 XHG=587 YBD=2785 YHG=2754>for " XBD=697 XHG=676 YBD=2785 YHG=2764>a " XBD=815 XHG=726 YBD=2794 YHG=2754>long " XBD=936 XHG=843 YBD=2785 YHG=2755>time " XBD=1064 XHG=966 YBD=2785 YHG=2754>after " XBD=1158 XHG=1092 YBD=2784 YHG=2754>the " XBD=1321 XHG=1187 YBD=2785 YHG=2753>visible" XBD=322 XHG=129 YBD=2830 YHG=2798>causative " XBD=461 XHG=348 YBD=2838 YHG=2800>agent " XBD=557 XHG=487 YBD=2829 YHG=2798>has " XBD=843 XHG=583 YBD=2838 YHG=2799>disappeared. " XBD=1000 XHG=896 YBD=2838 YHG=2799>They " XBD=1137 XHG=1026 YBD=2829 YHG=2799>made " XBD=1184 XHG=1162 YBD=2828 YHG=2808>a " XBD=1321 XHG=1211 YBD=2829 YHG=2798>series" XBD=168 XHG=130 YBD=2874 YHG=2843>of " XBD=486 XHG=197 YBD=2883 YHG=2842>implantations " XBD=556 XHG=518 YBD=2873 YHG=2843>of " XBD=711 XHG=586 YBD=2873 YHG=2843>sterile " XBD=902 XHG=741 YBD=2882 YHG=2843>purified " XBD=1099 XHG=931 YBD=2882 YHG=2843>collagen " XBD=1226 XHG=1128 YBD=2873 YHG=2843>from " XBD=1322 XHG=1255 YBD=2873 YHG=2842>the" XBD=265 XHG=130 YBD=2918 YHG=2896>cornea " XBD=322 XHG=284 YBD=2918 YHG=2887>of " XBD=406 XHG=339 YBD=2917 YHG=2887>the " XBD=473 XHG=425 YBD=2917 YHG=2896>ox " XBD=662 XHG=491 YBD=2918 YHG=2887>between " XBD=746 XHG=680 YBD=2917 YHG=2887>the " XBD=902 XHG=765 YBD=2918 YHG=2887>dermis " XBD=996 XHG=920 YBD=2917 YHG=2887>and " XBD=1080 XHG=1013 YBD=2918 YHG=2887>the " XBD=1322 XHG=1097 YBD=2926 YHG=2886>panniculus" XBD=309 XHG=132 YBD=2962 YHG=2941>carnosus " XBD=377 XHG=338 YBD=2962 YHG=2931>of " XBD=562 XHG=404 YBD=2961 YHG=2931>rabbits. " XBD=758 XHG=614 YBD=2970 YHG=2931>Biopsy " XBD=993 XHG=786 YBD=2971 YHG=2932>specimens " XBD=1116 XHG=1019 YBD=2962 YHG=2941>were " XBD=1322 XHG=1143 YBD=2962 YHG=2931>removed" XBD=171 XHG=131 YBD=3006 YHG=2977>at " XBD=350 XHG=205 YBD=3015 YHG=2975>weekly " XBD=567 XHG=385 YBD=3006 YHG=2975>intervals " XBD=680 XHG=604 YBD=3006 YHG=2975>and " XBD=738 XHG=715 YBD=3005 YHG=2985>a " XBD=876 XHG=773 YBD=3006 YHG=2984>more " XBD=954 XHG=913 YBD=3006 YHG=2985>or " XBD=1061 XHG=989 YBD=3006 YHG=2975>less " XBD=1323 XHG=1096 YBD=3006 YHG=2975>continuous" XBD=366 XHG=130 YBD=3060 YHG=3019>histological " XBD=551 XHG=404 YBD=3059 YHG=3016>picture " XBD=628 XHG=591 YBD=3049 YHG=3019>of " XBD=733 XHG=667 YBD=3049 YHG=3019>the " XBD=923 XHG=771 YBD=3050 YHG=3019>cellular " XBD=1129 XHG=961 YBD=3050 YHG=3020>reaction " XBD=1243 XHG=1166 YBD=3051 YHG=3029>was " XBD=1323 XHG=1283 YBD=3050 YHG=3029>so" XBD=325 XHG=132 YBD=3095 YHG=3064>obtained. " XBD=455 XHG=376 YBD=3094 YHG=3064>The |>" XBD=659 XHG=477 YBD=3103 YHG=3062>implants " XBD=776 XHG=680 YBD=3094 YHG=3072>were " XBD=947 XHG=797 YBD=3103 YHG=3064>rapidly " XBD=1205 XHG=971 YBD=3095 YHG=3064>surrounded " XBD=1279 XHG=1227 YBD=3103 YHG=3064>by " XBD=1324 XHG=1302 YBD=3095 YHG=3074>a" XBD=284 XHG=132 YBD=3139 YHG=3108>cellular " XBD=382 XHG=306 YBD=3139 YHG=3108>and " XBD=544 XHG=403 YBD=3139 YHG=3108>fibrous " XBD=739 XHG=565 YBD=3138 YHG=3107>vascular " XBD=924 XHG=761 YBD=3147 YHG=3107>capsule, " XBD=1069 XHG=946 YBD=3139 YHG=3108>which " XBD=1143 XHG=1090 YBD=3148 YHG=3108>by " XBD=1230 XHG=1164 YBD=3139 YHG=3108>the " XBD=1325 XHG=1252 YBD=3139 YHG=3108>end" XBD=171 XHG=133 YBD=3184 YHG=3152>of " XBD=263 XHG=197 YBD=3183 YHG=3152>the " XBD=420 XHG=289 YBD=3183 YHG=3152>fourth " XBD=550 XHG=445 YBD=3184 YHG=3152>week " XBD=698 XHG=576 YBD=3192 YHG=3152>began " XBD=765 XHG=724 YBD=3182 YHG=3153>to " XBD=846 XHG=791 YBD=3182 YHG=3152>fill " XBD=922 XHG=870 YBD=3192 YHG=3162>up " XBD=1042 XHG=948 YBD=3184 YHG=3152>with " XBD=1169 XHG=1068 YBD=3193 YHG=3152>large " XBD=1326 XHG=1195 YBD=3193 YHG=3153>foamy|>" XBD=75 XHG=71 YBD=3216 YHG=3205>’ " XBD=403 XHG=134 YBD=3237 YHG=3197>macrophages " XBD=692 XHG=423 YBD=3237 YHG=3196>accompanied " XBD=764 XHG=711 YBD=3236 YHG=3196>by " XBD=1049 XHG=783 YBD=3237 YHG=3196>lymphocytes " XBD=1145 XHG=1069 YBD=3228 YHG=3198>and " XBD=1325 XHG=1163 YBD=3237 YHG=3198>plasma-" XBD=232 XHG=134 YBD=3272 YHG=3241>cells. " XBD=460 XHG=286 YBD=3281 YHG=3241>Collagen " XBD=609 XHG=497 YBD=3272 YHG=3242>fibres " XBD=724 XHG=646 YBD=3272 YHG=3240>had " XBD=1010 XHG=762 YBD=3280 YHG=3240>disappeared " XBD=1099 XHG=1047 YBD=3281 YHG=3241>by " XBD=1203 XHG=1137 YBD=3272 YHG=3242>the " XBD=1326 XHG=1239 YBD=3272 YHG=3241>fifth" XBD=248 XHG=132 YBD=3321 YHG=3284>week, " XBD=356 XHG=286 YBD=3316 YHG=3285>but " XBD=459 XHG=393 YBD=3315 YHG=3285>the " XBD=768 XHG=499 YBD=3325 YHG=3285>macrophages " XBD=1007 XHG=805 YBD=3315 YHG=3285>contained " XBD=1252 XHG=1045 YBD=3325 YHG=3286>fragments " XBD=1329 XHG=1290 YBD=3316 YHG=3286>of" XBD=309 XHG=136 YBD=3360 YHG=3328>material " XBD=548 XHG=319 YBD=3370 YHG=3320>responding " XBD=600 XHG=559 YBD=3360 YHG=3331>to " XBD=781 XHG=614 YBD=3369 YHG=3329>collagen " XBD=924 XHG=794 YBD=3366 YHG=3329>stains, " XBD=1014 XHG=939 YBD=3360 YHG=3330>and " XBD=1133 XHG=1027 YBD=3361 YHG=3330>these " XBD=1329 XHG=1144 YBD=3370 YHG=3330>persisted" XBD=296 XHG=133 YBD=3405 YHG=3373>without " XBD=537 XHG=325 YBD=3415 YHG=3374>significant " XBD=710 XHG=567 YBD=3414 YHG=3374>change " XBD=839 XHG=738 YBD=3405 YHG=3374>until " XBD=931 XHG=865 YBD=3404 YHG=3374>the " XBD=1034 XHG=960 YBD=3405 YHG=3375>end " XBD=1102 XHG=1064 YBD=3405 YHG=3375>of " XBD=1196 XHG=1129 YBD=3405 YHG=3375>the " XBD=1328 XHG=1224 YBD=3405 YHG=3374>third

1. Horwitz, T. Surg. Gynec. Obstet. 1942, 74, 871.2. Pullinger, B. D. and Pirie, A. J. Path. Bact. 1942, 54, 341.

" XBD=1493 XHG=1347 YBD=218 YHG=184>month, " XBD=1636 XHG=1514 YBD=215 YHG=184>which " XBD=1687 XHG=1656 YBD=214 YHG=185>is " XBD=1748 XHG=1707 YBD=214 YHG=193>as " XBD=1826 XHG=1768 YBD=214 YHG=185>far " XBD=1887 XHG=1846 YBD=215 YHG=194>as " XBD=1973 XHG=1907 YBD=215 YHG=184>the " XBD=2260 XHG=1992 YBD=221 YHG=184>investigation " XBD=2354 XHG=2278 YBD=214 YHG=193>was " XBD=2519 XHG=2374 YBD=214 YHG=184>carried." XBD=1456 XHG=1346 YBD=259 YHG=227>After " XBD=1635 XHG=1482 YBD=267 YHG=228>making " XBD=1863 XHG=1663 YBD=259 YHG=228>allowance " XBD=1948 XHG=1889 YBD=258 YHG=228>for " XBD=2096 XHG=1974 YBD=258 YHG=228>minor " XBD=2336 XHG=2122 YBD=258 YHG=228>differences " XBD=2520 XHG=2361 YBD=258 YHG=227>between" XBD=1475 XHG=1347 YBD=302 YHG=271>rabbit " XBD=1585 XHG=1510 YBD=303 YHG=272>and " XBD=1761 XHG=1617 YBD=302 YHG=272>human " XBD=1984 XHG=1795 YBD=311 YHG=272>cytology, " XBD=2085 XHG=2019 YBD=302 YHG=272>the " XBD=2266 XHG=2118 YBD=311 YHG=271>general " XBD=2523 XHG=2297 YBD=310 YHG=270>histological" XBD=1495 XHG=1348 YBD=355 YHG=316>picture " XBD=1615 XHG=1519 YBD=346 YHG=316>after " XBD=1703 XHG=1638 YBD=346 YHG=316>the " XBD=1855 XHG=1725 YBD=346 YHG=316>fourth " XBD=1992 XHG=1877 YBD=351 YHG=316>week, " XBD=2125 XHG=2016 YBD=346 YHG=316>when " XBD=2212 XHG=2147 YBD=346 YHG=316>the " XBD=2398 XHG=2235 YBD=354 YHG=314>collagen " XBD=2522 XHG=2420 YBD=346 YHG=314>fibres" XBD=1610 XHG=1350 YBD=399 YHG=360>disappeared, " XBD=1718 XHG=1641 YBD=391 YHG=369>was " XBD=1888 XHG=1750 YBD=398 YHG=359>closely " XBD=2158 XHG=1919 YBD=398 YHG=359>comparable " XBD=2229 XHG=2189 YBD=389 YHG=360>to " XBD=2346 XHG=2261 YBD=388 YHG=359>that " XBD=2460 XHG=2378 YBD=388 YHG=367>seen |>" XBD=2524 XHG=2489 YBD=389 YHG=358>ih" XBD=1493 XHG=1348 YBD=434 YHG=403>human " XBD=1755 XHG=1513 YBD=442 YHG=403>non-specific " XBD=2065 XHG=1776 YBD=433 YHG=403>inflammation. " XBD=2290 XHG=2118 YBD=442 YHG=402>Collagen " XBD=2342 XHG=2310 YBD=432 YHG=402>is " XBD=2384 XHG=2362 YBD=431 YHG=411>a " XBD=2525 XHG=2403 YBD=441 YHG=402>highly" XBD=1527 XHG=1348 YBD=477 YHG=448>resistant " XBD=1772 XHG=1547 YBD=477 YHG=447>substance : " XBD=1837 XHG=1807 YBD=477 YHG=447>it " XBD=1887 XHG=1856 YBD=476 YHG=447>is " XBD=1953 XHG=1905 YBD=476 YHG=456>no " XBD=2075 XHG=1974 YBD=477 YHG=456>more " XBD=2188 XHG=2094 YBD=476 YHG=446>than " XBD=2329 XHG=2206 YBD=485 YHG=445>feebly " XBD=2525 XHG=2348 YBD=476 YHG=445>dissolved" XBD=1402 XHG=1349 YBD=530 YHG=491>by " XBD=1502 XHG=1426 YBD=530 YHG=500>any " XBD=1663 XHG=1526 YBD=521 YHG=491>known " XBD=1913 XHG=1686 YBD=530 YHG=490>proteolytic " XBD=2093 XHG=1937 YBD=530 YHG=500>enzyme " XBD=2237 XHG=2115 YBD=520 YHG=490>which " XBD=2380 XHG=2259 YBD=520 YHG=489>works " XBD=2527 XHG=2402 YBD=520 YHG=489>within" XBD=1416 XHG=1327 YBD=565 YHG=535>the " XBD=1754 XHG=1444 YBD=574 YHG=535>neighbourhood " XBD=1822 XHG=1783 YBD=564 YHG=535>of " XBD=2069 XHG=1849 YBD=573 YHG=534>neutrality. " XBD=2309 XHG=2121 YBD=572 YHG=533>Pullinger " XBD=2411 XHG=2337 YBD=563 YHG=533>and " XBD=2527 XHG=2437 YBD=564 YHG=533>Pirie" XBD=1502 XHG=1351 YBD=617 YHG=580>suggest " XBD=1607 XHG=1520 YBD=608 YHG=579>that " XBD=1656 XHG=1625 YBD=608 YHG=578>it " XBD=1705 XHG=1674 YBD=608 YHG=578>is " XBD=1788 XHG=1723 YBD=608 YHG=578>the " XBD=1964 XHG=1806 YBD=608 YHG=578>relative " XBD=2215 XHG=1981 YBD=615 YHG=577>insolubility " XBD=2272 XHG=2234 YBD=607 YHG=577>of " XBD=2354 XHG=2289 YBD=607 YHG=577>the " XBD=2528 XHG=2372 YBD=616 YHG=576>collagen" XBD=1439 XHG=1352 YBD=652 YHG=622>that " XBD=1493 XHG=1462 YBD=652 YHG=622>is " XBD=1746 XHG=1515 YBD=660 YHG=621>responsible " XBD=1827 XHG=1768 YBD=651 YHG=622>for " XBD=1915 XHG=1849 YBD=651 YHG=622>the " XBD=2106 XHG=1938 YBD=652 YHG=621>reaction " XBD=2205 XHG=2130 YBD=651 YHG=620>and " XBD=2277 XHG=2227 YBD=651 YHG=620>its " XBD=2528 XHG=2299 YBD=659 YHG=620>persistence," XBD=1429 XHG=1353 YBD=696 YHG=665>and " XBD=1533 XHG=1446 YBD=696 YHG=666>that " XBD=1600 XHG=1552 YBD=696 YHG=675>an " XBD=1821 XHG=1619 YBD=696 YHG=665>alteration " XBD=1877 XHG=1838 YBD=695 YHG=665>in " XBD=1961 XHG=1895 YBD=695 YHG=665>the " XBD=2316 XHG=1978 YBD=704 YHG=664>physicochemical " XBD=2530 XHG=2332 YBD=704 YHG=665>properties" XBD=1392 XHG=1353 YBD=740 YHG=709>of " XBD=1471 XHG=1405 YBD=740 YHG=709>the " XBD=1666 XHG=1486 YBD=749 YHG=709>subject’s " XBD=1764 XHG=1681 YBD=740 YHG=719>own " XBD=1849 XHG=1778 YBD=740 YHG=709>less " XBD=2007 XHG=1865 YBD=739 YHG=709>soluble " XBD=2228 XHG=2023 YBD=739 YHG=710>structures " XBD=2330 XHG=2244 YBD=747 YHG=717>may " XBD=2383 XHG=2345 YBD=738 YHG=708>in " XBD=2530 XHG=2397 YBD=739 YHG=709>certain" XBD=1455 XHG=1353 YBD=784 YHG=762>cases " XBD=1616 XHG=1467 YBD=784 YHG=753>initiate " XBD=1671 XHG=1629 YBD=784 YHG=754>it. " XBD=1828 XHG=1724 YBD=792 YHG=753>They " XBD=1890 XHG=1842 YBD=784 YHG=753>do " XBD=1971 XHG=1903 YBD=783 YHG=754>not " XBD=2094 XHG=1983 YBD=783 YHG=753>think " XBD=2193 XHG=2106 YBD=783 YHG=753>that " XBD=2271 XHG=2205 YBD=783 YHG=752>the " XBD=2531 XHG=2281 YBD=792 YHG=752>heterologous" XBD=1472 XHG=1354 YBD=837 YHG=797>origin " XBD=1538 XHG=1500 YBD=828 YHG=797>of " XBD=1629 XHG=1564 YBD=828 YHG=798>the " XBD=1823 XHG=1657 YBD=837 YHG=797>collagen " XBD=1988 XHG=1848 YBD=837 YHG=797>played " XBD=2036 XHG=2014 YBD=827 YHG=806>a " XBD=2274 XHG=2063 YBD=836 YHG=796>significant " XBD=2385 XHG=2300 YBD=835 YHG=798>part " XBD=2448 XHG=2410 YBD=827 YHG=796>in " XBD=2531 XHG=2472 YBD=828 YHG=798>the" XBD=1534 XHG=1353 YBD=877 YHG=842>reaction, " XBD=1704 XHG=1559 YBD=881 YHG=841>though " XBD=1866 XHG=1728 YBD=881 YHG=841>ideally " XBD=1912 XHG=1890 YBD=871 YHG=850>a " XBD=2082 XHG=1935 YBD=871 YHG=841>control " XBD=2213 XHG=2104 YBD=880 YHG=841>using " XBD=2474 XHG=2235 YBD=880 YHG=840>homologous " XBD=2533 XHG=2496 YBD=873 YHG=851>or" XBD=1450 XHG=1356 YBD=916 YHG=894>even " XBD=1709 XHG=1485 YBD=925 YHG=885>autologous " XBD=1911 XHG=1744 YBD=926 YHG=885>collagen " XBD=2127 XHG=1944 YBD=925 YHG=884>implants " XBD=2284 XHG=2159 YBD=916 YHG=884>would " XBD=2414 XHG=2317 YBD=916 YHG=884>have " XBD=2532 XHG=2446 YBD=918 YHG=886>been" XBD=1550 XHG=1356 YBD=960 YHG=929>desirable. " XBD=1714 XHG=1603 YBD=960 YHG=930>Their " XBD=1853 XHG=1736 YBD=970 YHG=940>paper " XBD=1943 XHG=1874 YBD=961 YHG=930>has " XBD=1992 XHG=1970 YBD=960 YHG=939>a " XBD=2172 XHG=2017 YBD=970 YHG=929>bearing " XBD=2243 XHG=2195 YBD=960 YHG=939>on " XBD=2532 XHG=2266 YBD=971 YHG=929>skin-grafting," XBD=1455 XHG=1355 YBD=1005 YHG=974>since " XBD=1571 XHG=1479 YBD=1005 YHG=974>such " XBD=1713 XHG=1594 YBD=1014 YHG=974>grafts " XBD=1890 XHG=1737 YBD=1005 YHG=974>contain " XBD=1935 XHG=1913 YBD=1005 YHG=984>a " XBD=2048 XHG=1958 YBD=1014 YHG=974>high " XBD=2294 XHG=2070 YBD=1014 YHG=976>percentage " XBD=2356 XHG=2318 YBD=1005 YHG=974>of " XBD=2533 XHG=2378 YBD=1015 YHG=974>collagen" XBD=1432 XHG=1356 YBD=1049 YHG=1018>and " XBD=1514 XHG=1452 YBD=1049 YHG=1027>are " XBD=1639 XHG=1534 YBD=1049 YHG=1018>often " XBD=1735 XHG=1658 YBD=1049 YHG=1018>laid " XBD=1914 XHG=1755 YBD=1058 YHG=1019>directly " XBD=1982 XHG=1933 YBD=1051 YHG=1028>on " XBD=2067 XHG=2001 YBD=1049 YHG=1019>the " XBD=2231 XHG=2087 YBD=1049 YHG=1018>surface " XBD=2289 XHG=2252 YBD=1048 YHG=1018>of " XBD=2535 XHG=2307 YBD=1058 YHG=1018>granulation" XBD=1486 XHG=1357 YBD=1093 YHG=1063>tissue.

PROPHYLACTIC TETANUS ANTITOXIN

" XBD=1493 XHG=1407 YBD=1226 YHG=1195>THE " XBD=1603 XHG=1511 YBD=1226 YHG=1195>War " XBD=1738 XHG=1623 YBD=1226 YHG=1194>Office " XBD=1920 XHG=1755 YBD=1226 YHG=1195>reminds " XBD=2099 XHG=1938 YBD=1226 YHG=1195>medical |>" XBD=2273 XHG=2116 YBD=1227 YHG=1195>officers1 " XBD=2376 XHG=2290 YBD=1226 YHG=1195>that " XBD=2537 XHG=2393 YBD=1228 YHG=1196>tetanus" XBD=1552 XHG=1359 YBD=1270 YHG=1239>antitoxin " XBD=1712 XHG=1577 YBD=1270 YHG=1239>should " XBD=1783 XHG=1736 YBD=1270 YHG=1235>be " XBD=1918 XHG=1807 YBD=1279 YHG=1239>given " XBD=1983 XHG=1943 YBD=1270 YHG=1241>to " XBD=2060 XHG=2009 YBD=1277 YHG=1239>all " XBD=2206 XHG=2082 YBD=1271 YHG=1239>battle " XBD=2427 XHG=2230 YBD=1271 YHG=1239>casualties " XBD=2535 XHG=2450 YBD=1272 YHG=1250>even" XBD=1506 XHG=1359 YBD=1323 YHG=1284>though " XBD=1608 XHG=1515 YBD=1324 YHG=1284>they " XBD=1716 XHG=1617 YBD=1315 YHG=1283>have " XBD=1803 XHG=1726 YBD=1315 YHG=1283>had " XBD=1969 XHG=1815 YBD=1315 YHG=1285>tetanus " XBD=2112 XHG=1979 YBD=1314 YHG=1283>toxoid " XBD=2160 XHG=2121 YBD=1315 YHG=1283>in " XBD=2235 XHG=2169 YBD=1315 YHG=1284>the " XBD=2332 XHG=2244 YBD=1323 YHG=1285>past " XBD=2383 XHG=2343 YBD=1315 YHG=1293>or " XBD=2539 XHG=2395 YBD=1316 YHG=1285>tetanus" XBD=1552 XHG=1361 YBD=1359 YHG=1328>antitoxin " XBD=1757 XHG=1577 YBD=1368 YHG=1328>recently. " XBD=1846 XHG=1810 YBD=1359 YHG=1328>It " XBD=2003 XHG=1866 YBD=1359 YHG=1327>should " XBD=2098 XHG=2020 YBD=1359 YHG=1328>also " XBD=2165 XHG=2118 YBD=1359 YHG=1328>be " XBD=2303 XHG=2192 YBD=1369 YHG=1329>given " XBD=2360 XHG=2319 YBD=1359 YHG=1330>to " XBD=2539 XHG=2382 YBD=1368 YHG=1329>patients" XBD=1540 XHG=1361 YBD=1413 YHG=1372>suffering " XBD=1648 XHG=1549 YBD=1404 YHG=1373>from " XBD=1735 XHG=1660 YBD=1412 YHG=1382>any " XBD=1884 XHG=1745 YBD=1404 YHG=1373>wound " XBD=2016 XHG=1893 YBD=1404 YHG=1372>which " XBD=2147 XHG=2028 YBD=1405 YHG=1382>seems " XBD=2272 XHG=2156 YBD=1412 YHG=1373>likely " XBD=2322 XHG=2281 YBD=1404 YHG=1375>to " XBD=2380 XHG=2333 YBD=1404 YHG=1373>be " XBD=2539 XHG=2386 YBD=1405 YHG=1373>infected" XBD=1453 XHG=1359 YBD=1449 YHG=1417>with " XBD=1637 XHG=1472 YBD=1448 YHG=1419>tetanus. " XBD=1811 XHG=1688 YBD=1449 YHG=1417>When " XBD=2015 XHG=1825 YBD=1448 YHG=1417>antitoxin " XBD=2059 XHG=2028 YBD=1448 YHG=1418>is " XBD=2184 XHG=2072 YBD=1457 YHG=1417>given " XBD=2507 XHG=2198 YBD=1458 YHG=1417>subcutaneously " XBD=2540 XHG=2520 YBD=1449 YHG=1428>a" XBD=1572 XHG=1362 YBD=1493 YHG=1462>maximum " XBD=1685 XHG=1588 YBD=1493 YHG=1461>level " XBD=1740 XHG=1700 YBD=1492 YHG=1461>in " XBD=1822 XHG=1756 YBD=1493 YHG=1461>the " XBD=1953 XHG=1839 YBD=1492 YHG=1461>blood " XBD=2000 XHG=1970 YBD=1493 YHG=1462>is " XBD=2085 XHG=2017 YBD=1493 YHG=1463>not " XBD=2266 XHG=2104 YBD=1493 YHG=1462>reached " XBD=2341 XHG=2282 YBD=1493 YHG=1462>for " XBD=2427 XHG=2360 YBD=1493 YHG=1463>3-4 " XBD=2540 XHG=2443 YBD=1502 YHG=1462>days," XBD=1527 XHG=1361 YBD=1538 YHG=1506>whereas " XBD=1573 XHG=1543 YBD=1537 YHG=1507>if " XBD=1618 XHG=1587 YBD=1537 YHG=1507>it " XBD=1665 XHG=1633 YBD=1537 YHG=1506>is " XBD=1792 XHG=1680 YBD=1546 YHG=1506>given " XBD=1860 XHG=1808 YBD=1546 YHG=1506>by " XBD=1970 XHG=1877 YBD=1546 YHG=1506>deep " XBD=2278 XHG=1986 YBD=1538 YHG=1506>intramuscular " XBD=2468 XHG=2292 YBD=1547 YHG=1506>injection " XBD=2541 XHG=2483 YBD=1539 YHG=1508>the" XBD=1467 XHG=1364 YBD=1582 YHG=1561>same " XBD=1534 XHG=1493 YBD=1582 YHG=1561>or " XBD=1583 XHG=1561 YBD=1582 YHG=1561>a " XBD=1739 XHG=1607 YBD=1591 YHG=1551>higher " XBD=1860 XHG=1763 YBD=1582 YHG=1551>level " XBD=1915 XHG=1884 YBD=1582 YHG=1551>is " XBD=2100 XHG=1940 YBD=1582 YHG=1551>reached " XBD=2239 XHG=2126 YBD=1582 YHG=1551>much " XBD=2367 XHG=2265 YBD=1582 YHG=1560>more " XBD=2542 XHG=2391 YBD=1591 YHG=1551>rapidly," XBD=1603 XHG=1366 YBD=1636 YHG=1596>appreciable " XBD=1836 XHG=1630 YBD=1635 YHG=1596>quantities " XBD=1900 XHG=1861 YBD=1626 YHG=1595>of " XBD=2115 XHG=1924 YBD=1627 YHG=1596>antitoxin " XBD=2251 XHG=2139 YBD=1636 YHG=1596>being " XBD=2542 XHG=2276 YBD=1627 YHG=1596>demonstrable" XBD=1405 XHG=1365 YBD=1672 YHG=1642>in " XBD=1495 XHG=1429 YBD=1671 YHG=1641>the " XBD=1633 XHG=1520 YBD=1671 YHG=1640>blood " XBD=1791 XHG=1657 YBD=1672 YHG=1640>within " XBD=1838 XHG=1816 YBD=1671 YHG=1650>a " XBD=1934 XHG=1861 YBD=1671 YHG=1640>few " XBD=2083 XHG=1957 YBD=1672 YHG=1641>hours. " XBD=2239 XHG=2135 YBD=1680 YHG=1641>Deep " XBD=2543 XHG=2265 YBD=1671 YHG=1640>intramuscular" XBD=1679 XHG=1365 YBD=1725 YHG=1685>injection-into " XBD=1778 XHG=1712 YBD=1716 YHG=1685>the " XBD=1987 XHG=1811 YBD=1721 YHG=1684>deltoid, " XBD=2065 XHG=1999 YBD=1716 YHG=1685>the " XBD=2342 XHG=2098 YBD=1725 YHG=1685>subscapular " XBD=2414 XHG=2374 YBD=1715 YHG=1694>or " XBD=2543 XHG=2446 YBD=1715 YHG=1686>outer" XBD=1559 XHG=1369 YBD=1770 YHG=1730>quadrant " XBD=1616 XHG=1578 YBD=1761 YHG=1730>of " XBD=1698 XHG=1632 YBD=1761 YHG=1729>the " XBD=1858 XHG=1716 YBD=1770 YHG=1729>gluteal " XBD=2208 XHG=1874 YBD=1770 YHG=1729>regions-should " XBD=2409 XHG=2224 YBD=1761 YHG=1729>therefore " XBD=2470 XHG=2425 YBD=1760 YHG=1729>be " XBD=2546 XHG=2486 YBD=1760 YHG=1729>the" XBD=1516 XHG=1368 YBD=1807 YHG=1775>normal " XBD=1709 XHG=1560 YBD=1813 YHG=1777>route ; " XBD=2017 XHG=1770 YBD=1806 YHG=1775>intravenous " XBD=2368 XHG=2063 YBD=1806 YHG=1774>administration " XBD=2442 XHG=2411 YBD=1805 YHG=1774>is " XBD=2546 XHG=2484 YBD=1805 YHG=1776>not" XBD=1659 XHG=1368 YBD=1851 YHG=1820>recommended " XBD=1759 XHG=1698 YBD=1860 YHG=1820>for |>" XBD=2051 XHG=1799 YBD=1861 YHG=1820>prophylactic " XBD=2159 XHG=2095 YBD=1852 YHG=1830>use " XBD=2363 XHG=2203 YBD=1851 YHG=1819>because " XBD=2445 XHG=2406 YBD=1850 YHG=1819>of " XBD=2545 XHG=2486 YBD=1850 YHG=1819>the" XBD=1583 XHG=1368 YBD=1905 YHG=1864>possibility " XBD=1637 XHG=1598 YBD=1895 YHG=1864>of " XBD=1918 XHG=1652 YBD=1904 YHG=1864>anaphylactic " XBD=2111 XHG=1931 YBD=1895 YHG=1864>reaction. " XBD=2242 XHG=2163 YBD=1895 YHG=1864>The " XBD=2451 XHG=2257 YBD=1895 YHG=1864>minimum " XBD=2547 XHG=2467 YBD=1894 YHG=1863>dose" XBD=1506 XHG=1370 YBD=1940 YHG=1909>should " XBD=1582 XHG=1534 YBD=1940 YHG=1909>be " XBD=1705 XHG=1613 YBD=1940 YHG=1910>3000 " XBD=1849 XHG=1734 YBD=1945 YHG=1909>units, " XBD=1950 XHG=1880 YBD=1939 YHG=1909>but " XBD=2056 XHG=1979 YBD=1939 YHG=1909>this " XBD=2220 XHG=2086 YBD=1939 YHG=1909>should " XBD=2296 XHG=2249 YBD=1939 YHG=1908>be " XBD=2484 XHG=2326 YBD=1939 YHG=1908>doubled " XBD=2547 XHG=2512 YBD=1938 YHG=1917>or" XBD=1517 XHG=1369 YBD=1985 YHG=1953>trebled " XBD=1659 XHG=1535 YBD=1985 YHG=1953>where " XBD=1784 XHG=1678 YBD=1985 YHG=1954>there " XBD=1867 XHG=1805 YBD=1985 YHG=1963>are " XBD=1980 XHG=1887 YBD=1993 YHG=1962>very " XBD=2079 XHG=1997 YBD=1984 YHG=1953>foul " XBD=2285 XHG=2096 YBD=1984 YHG=1953>lacerated " XBD=2469 XHG=2303 YBD=1984 YHG=1952>wounds. " XBD=2548 XHG=2518 YBD=1982 YHG=1952>If" XBD=1478 XHG=1370 YBD=2030 YHG=1998>there " XBD=1533 XHG=1503 YBD=2029 YHG=1998>is " XBD=1834 XHG=1560 YBD=2039 YHG=1998>documentary " XBD=2038 XHG=1859 YBD=2029 YHG=1997>evidence " XBD=2102 XHG=2063 YBD=2029 YHG=1998>of " XBD=2252 XHG=2127 YBD=2029 YHG=1998>active " XBD=2548 XHG=2275 YBD=2029 YHG=1996>immunisation" XBD=1464 XHG=1370 YBD=2075 YHG=2043>with " XBD=1631 XHG=1476 YBD=2075 YHG=2044>tetanus " XBD=1776 XHG=1643 YBD=2077 YHG=2043>toxoid " XBD=1811 XHG=1789 YBD=2074 YHG=2052>a " XBD=1940 XHG=1824 YBD=2084 YHG=2043>single " XBD=2042 XHG=1953 YBD=2075 YHG=2044>dose " XBD=2094 XHG=2055 YBD=2074 YHG=2043>of " XBD=2296 XHG=2106 YBD=2075 YHG=2043>antitoxin " XBD=2339 XHG=2308 YBD=2074 YHG=2043>is " XBD=2548 XHG=2352 YBD=2079 YHG=2041>sufficient;" XBD=1570 XHG=1373 YBD=2118 YHG=2087>otherwise " XBD=1660 XHG=1584 YBD=2119 YHG=2089>two " XBD=1822 XHG=1674 YBD=2118 YHG=2087>further " XBD=1944 XHG=1837 YBD=2119 YHG=2088>doses " XBD=1999 XHG=1961 YBD=2118 YHG=2088>of " XBD=2108 XHG=2016 YBD=2119 YHG=2089>3000 " XBD=2225 XHG=2123 YBD=2119 YHG=2088>units " XBD=2374 XHG=2241 YBD=2118 YHG=2087>should " XBD=2435 XHG=2388 YBD=2118 YHG=2087>be " XBD=2549 XHG=2448 YBD=2126 YHG=2086>given" XBD=1415 XHG=1374 YBD=2163 YHG=2134>at " XBD=1579 XHG=1433 YBD=2171 YHG=2131>weekly " XBD=1789 XHG=1595 YBD=2163 YHG=2131>intervals.

SURFACE FREEZING FOR DEEP PAIN

" XBD=1512 XHG=1426 YBD=2300 YHG=2272>THE " XBD=1644 XHG=1530 YBD=2301 YHG=2272>views " XBD=1705 XHG=1663 YBD=2301 YHG=2272>of " XBD=1873 XHG=1720 YBD=2301 YHG=2271>Leriche " XBD=1942 XHG=1892 YBD=2301 YHG=2280>on " XBD=2024 XHG=1960 YBD=2301 YHG=2272>the " XBD=2154 XHG=2043 YBD=2301 YHG=2272>value " XBD=2215 XHG=2173 YBD=2301 YHG=2271>of " XBD=2325 XHG=2228 YBD=2301 YHG=2272>local " XBD=2553 XHG=2342 YBD=2301 YHG=2270>anaesthesia." XBD=1416 XHG=1376 YBD=2340 YHG=2311>in " XBD=1667 XHG=1449 YBD=2349 YHG=2311>promoting " XBD=1877 XHG=1698 YBD=2347 YHG=2320>recovery " XBD=2008 XHG=1909 YBD=2340 YHG=2311>from " XBD=2174 XHG=2041 YBD=2349 YHG=2311>simple " XBD=2453 XHG=2206 YBD=2348 YHG=2312>ligamentous " XBD=2552 XHG=2485 YBD=2340 YHG=2310>and" XBD=1567 XHG=1376 YBD=2380 YHG=2351>muscular " XBD=1742 XHG=1587 YBD=2387 YHG=2351>injuries " XBD=1825 XHG=1762 YBD=2380 YHG=2360>are " XBD=1929 XHG=1845 YBD=2380 YHG=2360>now " XBD=2086 XHG=1950 YBD=2388 YHG=2351>widely " XBD=2298 XHG=2107 YBD=2387 YHG=2351>accepted. " XBD=2427 XHG=2350 YBD=2380 YHG=2351>The " XBD=2552 XHG=2447 YBD=2380 YHG=2350>aboli-" XBD=1461 XHG=1377 YBD=2419 YHG=2391>tion " XBD=1531 XHG=1488 YBD=2419 YHG=2390>of " XBD=1716 XHG=1554 YBD=2420 YHG=2400>nervous " XBD=1921 XHG=1743 YBD=2427 YHG=2391>impulses " XBD=2047 XHG=1947 YBD=2420 YHG=2391>from " XBD=2139 XHG=2073 YBD=2420 YHG=2391>the " XBD=2351 XHG=2167 YBD=2427 YHG=2390>damaged " XBD=2554 XHG=2378 YBD=2420 YHG=2390>structure" XBD=1586 XHG=1377 YBD=2466 YHG=2431>interrupts " XBD=1694 XHG=1629 YBD=2459 YHG=2430>the " XBD=1870 XHG=1726 YBD=2459 YHG=2430>vicious " XBD=2011 XHG=1904 YBD=2459 YHG=2430>circle " XBD=2086 XHG=2044 YBD=2459 YHG=2430>of " XBD=2235 XHG=2122 YBD=2459 YHG=2430>reflex " XBD=2551 XHG=2267 YBD=2467 YHG=2430>muscle-spasm," XBD=1676 XHG=1378 YBD=2499 YHG=2469>vasodilatation " XBD=1782 XHG=1706 YBD=2498 YHG=2469>and " XBD=1974 XHG=1814 YBD=2505 YHG=2470>oedema, " XBD=2082 XHG=2005 YBD=2499 YHG=2470>and " XBD=2335 XHG=2112 YBD=2499 YHG=2470>accelerates " XBD=2491 XHG=2365 YBD=2499 YHG=2470>return " XBD=2556 XHG=2518 YBD=2499 YHG=2471>to" XBD=1525 XHG=1378 YBD=2538 YHG=2509>normal " XBD=1729 XHG=1543 YBD=2538 YHG=2509>function. " XBD=1869 XHG=1781 YBD=2539 YHG=2509>Two " XBD=2025 XHG=1889 YBD=2546 YHG=2519>papers " XBD=2084 XHG=2044 YBD=2538 YHG=2509>in " XBD=2180 XHG=2103 YBD=2538 YHG=2509>this " XBD=2296 XHG=2199 YBD=2539 YHG=2510>issue " XBD=2479 XHG=2317 YBD=2539 YHG=2510>describe " XBD=2557 XHG=2498 YBD=2539 YHG=2509>the" XBD=1539 XHG=1378 YBD=2578 YHG=2549>benefits " XBD=1608 XHG=1565 YBD=2578 YHG=2549>of " XBD=1793 XHG=1629 YBD=2586 YHG=2549>freezing " XBD=1884 XHG=1818 YBD=2578 YHG=2549>the " XBD=1995 XHG=1910 YBD=2579 YHG=2549>skin " XBD=2113 XHG=2019 YBD=2579 YHG=2549>with " XBD=2244 XHG=2139 YBD=2585 YHG=2549>ethyl " XBD=2433 XHG=2271 YBD=2579 YHG=2549>chloride " XBD=2556 XHG=2457 YBD=2579 YHG=2549>when" XBD=1529 XHG=1379 YBD=2625 YHG=2589>dealing " XBD=1647 XHG=1552 YBD=2618 YHG=2589>with " XBD=1896 XHG=1672 YBD=2626 YHG=2589>underlying " XBD=2068 XHG=1921 YBD=2626 YHG=2589>painful " XBD=2228 XHG=2093 YBD=2618 YHG=2589>lesions " XBD=2297 XHG=2255 YBD=2618 YHG=2588>of " XBD=2395 XHG=2319 YBD=2618 YHG=2589>soft " XBD=2556 XHG=2419 YBD=2623 YHG=2589>tissues," XBD=1640 XHG=1378 YBD=2665 YHG=2628>periarticular " XBD=1870 XHG=1664 YBD=2658 YHG=2629>structures " XBD=1936 XHG=1895 YBD=2657 YHG=2638>or " XBD=2055 XHG=1961 YBD=2658 YHG=2638>even " XBD=2228 XHG=2078 YBD=2658 YHG=2628>chronic " XBD=2351 XHG=2252 YBD=2665 YHG=2628>joint " XBD=2556 XHG=2373 YBD=2658 YHG=2629>affections" XBD=1455 XHG=1378 YBD=2697 YHG=2669>and " XBD=1664 XHG=1467 YBD=2698 YHG=2669>fractures. " XBD=1848 XHG=1715 YBD=2705 YHG=2668>Henry " XBD=2046 XHG=1859 YBD=2698 YHG=2668>describes " XBD=2218 XHG=2058 YBD=2705 YHG=2668>striking " XBD=2336 XHG=2228 YBD=2697 YHG=2668>relief " XBD=2380 XHG=2342 YBD=2698 YHG=2668>in " XBD=2411 XHG=2389 YBD=2698 YHG=2679>a " XBD=2558 XHG=2420 YBD=2705 YHG=2669>variety" XBD=1424 XHG=1380 YBD=2738 YHG=2708>of " XBD=1566 XHG=1451 YBD=2743 YHG=2717>cases, " XBD=1707 XHG=1597 YBD=2738 YHG=2708>while " XBD=1935 XHG=1737 YBD=2738 YHG=2707>McIntosh " XBD=2042 XHG=1966 YBD=2737 YHG=2708>and " XBD=2209 XHG=2072 YBD=2743 YHG=2708>Petrie, " XBD=2389 XHG=2240 YBD=2746 YHG=2708>writing " XBD=2511 XHG=2418 YBD=2738 YHG=2708>from " XBD=2559 XHG=2538 YBD=2737 YHG=2717>a" XBD=1577 XHG=1382 YBD=2778 YHG=2747>Canadian " XBD=1767 XHG=1601 YBD=2785 YHG=2748>hospital " XBD=1833 XHG=1793 YBD=2777 YHG=2748>in " XBD=2021 XHG=1858 YBD=2783 YHG=2747>Britain, " XBD=2178 XHG=2048 YBD=2777 YHG=2747>record " XBD=2347 XHG=2204 YBD=2777 YHG=2747>similar " XBD=2502 XHG=2371 YBD=2778 YHG=2749>results " XBD=2559 XHG=2524 YBD=2778 YHG=2749>in" XBD=1505 XHG=1380 YBD=2817 YHG=2787>minor " XBD=1698 XHG=1531 YBD=2824 YHG=2788>injuries, " XBD=1974 XHG=1727 YBD=2824 YHG=2788>particularly " XBD=2145 XHG=1999 YBD=2817 YHG=2787>around " XBD=2237 XHG=2172 YBD=2817 YHG=2788>the " XBD=2499 XHG=2266 YBD=2825 YHG=2787>ankle-joint, " XBD=2559 XHG=2523 YBD=2817 YHG=2788>in" XBD=1547 XHG=1381 YBD=2857 YHG=2827>soldiers. " XBD=1719 XHG=1600 YBD=2856 YHG=2827>There " XBD=1766 XHG=1735 YBD=2856 YHG=2827>is " XBD=1832 XHG=1783 YBD=2856 YHG=2837>no " XBD=1972 XHG=1851 YBD=2856 YHG=2827>doubt " XBD=2076 XHG=1988 YBD=2856 YHG=2827>that " XBD=2158 XHG=2092 YBD=2856 YHG=2827>the " XBD=2332 XHG=2176 YBD=2856 YHG=2827>method " XBD=2478 XHG=2349 YBD=2863 YHG=2828>works, " XBD=2560 XHG=2496 YBD=2857 YHG=2828>but" XBD=1648 XHG=1382 YBD=2903 YHG=2866>explanations " XBD=1716 XHG=1672 YBD=2895 YHG=2866>of " XBD=1786 XHG=1736 YBD=2895 YHG=2866>its " XBD=1940 XHG=1811 YBD=2895 YHG=2867>action " XBD=2028 XHG=1965 YBD=2895 YHG=2875>are " XBD=2212 XHG=2051 YBD=2905 YHG=2866>lacking. " XBD=2395 XHG=2264 YBD=2904 YHG=2867>Henry " XBD=2558 XHG=2420 YBD=2897 YHG=2867>demon-" XBD=1529 XHG=1383 YBD=2935 YHG=2902>strated " XBD=1604 XHG=1551 YBD=2943 YHG=2906>by " XBD=1809 XHG=1625 YBD=2942 YHG=2906>inserting " XBD=1853 XHG=1830 YBD=2935 YHG=2915>a " XBD=2144 XHG=1874 YBD=2935 YHG=2906>thermometer " XBD=2246 XHG=2164 YBD=2935 YHG=2906>into " XBD=2334 XHG=2269 YBD=2936 YHG=2907>the " XBD=2462 XHG=2356 YBD=2943 YHG=2907>thigh " XBD=2562 XHG=2483 YBD=2936 YHG=2908>that" XBD=1449 XHG=1383 YBD=2975 YHG=2945>the " XBD=1616 XHG=1464 YBD=2982 YHG=2945>chilling " XBD=1719 XHG=1630 YBD=2975 YHG=2946>does " XBD=1802 XHG=1733 YBD=2974 YHG=2946>not " XBD=1927 XHG=1815 YBD=2974 YHG=2946>reach " XBD=2035 XHG=1941 YBD=2982 YHG=2945>deep " XBD=2269 XHG=2050 YBD=2980 YHG=2945>structures, " XBD=2360 XHG=2283 YBD=2975 YHG=2946>and " XBD=2430 XHG=2372 YBD=2975 YHG=2946>his " XBD=2560 XHG=2442 YBD=2983 YHG=2947>happy" XBD=1604 XHG=1384 YBD=3021 YHG=2985>experience " XBD=1722 XHG=1627 YBD=3014 YHG=2985>with " XBD=1768 XHG=1745 YBD=3014 YHG=2994>a " XBD=2014 XHG=1794 YBD=3021 YHG=2985>colleague’s " XBD=2262 XHG=2040 YBD=3014 YHG=2984>dachshund " XBD=2404 XHG=2287 YBD=3014 YHG=2994>seems " XBD=2468 XHG=2428 YBD=3015 YHG=2986>to " XBD=2560 XHG=2491 YBD=3015 YHG=2986>rule" XBD=1454 XHG=1385 YBD=3053 YHG=3025>out " XBD=1550 XHG=1485 YBD=3053 YHG=3025>the " XBD=1744 XHG=1582 YBD=3053 YHG=3024>element " XBD=1818 XHG=1775 YBD=3053 YHG=3024>of " XBD=2071 XHG=1844 YBD=3061 YHG=3024>suggestion. " XBD=2202 XHG=2124 YBD=3053 YHG=3025>The " XBD=2316 XHG=2231 YBD=3054 YHG=3034>now " XBD=2558 XHG=2348 YBD=3055 YHG=3024>established" XBD=1489 XHG=1384 YBD=3093 YHG=3064>work " XBD=1547 XHG=1505 YBD=3093 YHG=3064>of Kellgren " XBD=1830 XHG=1753 YBD=3092 YHG=3064>2 on " XBD=1935 XHG=1843 YBD=3100 YHG=3064>pain " XBD=2111 XHG=1948 YBD=3093 YHG=3063>referred " XBD=2301 XHG=2127 YBD=3101 YHG=3063>diffusely " XBD=2412 XHG=2315 YBD=3093 YHG=3063>from " XBD=2561 XHG=2426 YBD=3094 YHG=3073>muscu-" XBD=1443 XHG=1386 YBD=3132 YHG=3103>lar " XBD=1540 XHG=1464 YBD=3133 YHG=3104>and " XBD=1813 XHG=1561 YBD=3140 YHG=3103>ligamentous " XBD=1908 XHG=1833 YBD=3132 YHG=3103>foci " XBD=2048 XHG=1929 YBD=3132 YHG=3112>seems " XBD=2251 XHG=2069 YBD=3133 YHG=3103>relevant. " XBD=2342 XHG=2303 YBD=3133 YHG=3104>It " XBD=2392 XHG=2361 YBD=3133 YHG=3104>is " XBD=2562 XHG=2413 YBD=3140 YHG=3104>possible" XBD=1475 XHG=1387 YBD=3172 YHG=3143>that " XBD=1824 XHG=1497 YBD=3172 YHG=3143>ansesthetisation " XBD=1889 XHG=1845 YBD=3172 YHG=3142>of " XBD=1971 XHG=1905 YBD=3172 YHG=3143>the " XBD=2203 XHG=1992 YBD=3180 YHG=3143>superficial " XBD=2311 XHG=2223 YBD=3172 YHG=3152>area " XBD=2374 XHG=2332 YBD=3173 YHG=3143>of " XBD=2563 XHG=2390 YBD=3172 YHG=3143>reference" XBD=1441 XHG=1387 YBD=3220 YHG=3182>by " XBD=1632 XHG=1468 YBD=3220 YHG=3183>freezing " XBD=1750 XHG=1660 YBD=3219 YHG=3192>may " XBD=1925 XHG=1778 YBD=3212 YHG=3182>abolish " XBD=2019 XHG=1953 YBD=3212 YHG=3183>the " XBD=2149 XHG=2047 YBD=3220 YHG=3183>pain, " XBD=2221 XHG=2180 YBD=3212 YHG=3192>as " XBD=2288 XHG=2249 YBD=3212 YHG=3183>in " XBD=2381 XHG=2316 YBD=3213 YHG=3183>the " XBD=2564 XHG=2409 YBD=3212 YHG=3182>classical" XBD=1536 XHG=1388 YBD=3258 YHG=3223>though " XBD=1737 XHG=1559 YBD=3259 YHG=3222>disputed " XBD=2013 XHG=1760 YBD=3258 YHG=3223>experiments " XBD=2075 XHG=2036 YBD=3251 YHG=3223>in " XBD=2220 XHG=2097 YBD=3251 YHG=3222>which " XBD=2403 XHG=2242 YBD=3252 YHG=3222>referred " XBD=2510 XHG=2425 YBD=3258 YHG=3222>pain " XBD=2568 XHG=2531 YBD=3251 YHG=3221>of" XBD=1692 XHG=1390 YBD=3297 YHG=3261>diaphragmatic " XBD=1842 XHG=1721 YBD=3297 YHG=3261>origin " XBD=1942 XHG=1865 YBD=3291 YHG=3270>was " XBD=2162 XHG=1968 YBD=3290 YHG=3261>abolished " XBD=2239 XHG=2187 YBD=3298 YHG=3262>by " XBD=2484 XHG=2263 YBD=3296 YHG=3261>infiltrating " XBD=2564 XHG=2506 YBD=3289 YHG=3261>the" XBD=1475 XHG=1389 YBD=3330 YHG=3300>skin " XBD=1536 XHG=1493 YBD=3330 YHG=3300>of " XBD=1616 XHG=1551 YBD=3330 YHG=3301>the " XBD=1812 XHG=1635 YBD=3331 YHG=3300>shoulder " XBD=1923 XHG=1828 YBD=3330 YHG=3300>with " XBD=2128 XHG=1940 YBD=3337 YHG=3301>procaine. " XBD=2259 XHG=2179 YBD=3330 YHG=3301>But " XBD=2352 XHG=2276 YBD=3330 YHG=3301>this " XBD=2400 XHG=2369 YBD=3329 YHG=3300>is " XBD=2566 XHG=2419 YBD=3328 YHG=3300>another" XBD=1433 XHG=1389 YBD=3370 YHG=3340>of " XBD=1566 XHG=1457 YBD=3370 YHG=3340>those " XBD=1861 XHG=1594 YBD=3370 YHG=3339>well-founded " XBD=2037 XHG=1890 YBD=3369 YHG=3340>clinical " XBD=2326 XHG=2064 YBD=3370 YHG=3340>observations " XBD=2472 XHG=2353 YBD=3370 YHG=3338>which " XBD=2567 XHG=2498 YBD=3367 YHG=3337>still" XBD=1505 XHG=1389 YBD=3409 YHG=3380>await " XBD=1590 XHG=1524 YBD=3409 YHG=3380>the " XBD=1840 XHG=1609 YBD=3409 YHG=3379>elucidation " XBD=1901 XHG=1858 YBD=3409 YHG=3380>of " XBD=2058 XHG=1917 YBD=3409 YHG=3380>careful " XBD=2257 XHG=2077 YBD=3410 YHG=3380>scientific " XBD=2455 XHG=2276 YBD=3409 YHG=3378>research.

1. Army med. Direct. Bull. July, 1942, p. 3.2. Kellgren, H. J. Clin. Sci. 1938, 3, 174.