Sulfone-Mediated Synthesis of Polysubstituted Pyridines.

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2005 Pyridine derivatives R 0380 Sulfone-Mediated Synthesis of Polysubstituted Pyridines. — The synthesis of py- ridines is achieved by a straightforward route via bis allylation of the tolylacetate (I) followed by ozonolysis and cyclization intermediate diones such as (VI). — (CRAIG*, D.; HENRY, G. D.; Tetrahedron Lett. 46 (2005) 15, 2559-2562; Dep. Chem., Imp. Coll., London SW7 2AZ, UK; Eng.) — Mais 32- 143

Transcript of Sulfone-Mediated Synthesis of Polysubstituted Pyridines.

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2005

Pyridine derivativesR 0380 Sulfone-Mediated Synthesis of Polysubstituted Pyridines. — The synthesis of py-

ridines is achieved by a straightforward route via bis allylation of the tolylacetate (I) followed by ozonolysis and cyclization intermediate diones such as (VI). — (CRAIG*, D.; HENRY, G. D.; Tetrahedron Lett. 46 (2005) 15, 2559-2562; Dep. Chem., Imp. Coll., London SW7 2AZ, UK; Eng.) — Mais

32- 143