Subject Index, Volume 1

A

Adult polycystic kidney disease, with diabetic intercapillary glomerulosclerosis (letter), 32

Albumin, urinary insulin-dependent diabetes and, 76

-maturity onset non-insulin-dependent diabetes and, 132

measurement of, 58 Albuminuria, antihypertensive treatment and, 45 Antihylbertensive treatment, renal function and, 45 Armanni-Ebstein lesion, genesis of, in diabetic

nephropathy, 2

Biopsy, renal, necessity of, in nephropathic diabetic, 1 Blood glucose control, see a lso Metabolic control

correlation with renal histopathology and duration of diabetes, 41

Blood pressure, see a lso Hypertension microalbuminuria and, in maturity onset

non-insulin-dependent diabetes, 132 nephropathy progression and, 53

Blood rheology, glomerular filtration and, nephropathy pathogenesis and, 137

C

Co-morbidity, uremia and, 73 Complications, patient experience and physician

response to, 65 Continuous ambulatory peritoneal dialysis

(CAPD), 11, 20 decreasing insulin requirements with, 16

Continuous subcutaneous insulin infusion (CSlI) and kidney function and size in IDDM patients, 91 and metabolic control in kidney transplanted

insulin-dependent diabetics, 81 Cyclosporine, renal function and, in non-uremic

diabetic recipients of pancreas transplants, 128

D

Diabetic nephropathy, see Nephropathy Diabetic retinopathy, see Retinopathy Dialysis, see Continuous ambulatory peritoneal

dialysis; Hemodialysis Dietary protein, nephropathy and, 37 Double immunofluorescence, glomerular sialic acids

and, 61

E

Enzyme immunoassay, microalbuminuria detection with, 58

F

Factor VIII, near normoglycemia and, in Type I diabetes, 100

G

Glomerular filtration, blood rheology and, nephropathy pathogenesis and, 137

Glomerular filtration rate (GFR), 7 Glomerular injury, in Type II diabetes, obese Zucker rat

model of, 26

Glomerular sialic acids, 61 Glomerulopathy, advanced, new vessel formation in

renal corpuscles in, 122 Glomerulosclerosis

intercapillary, adult polycystic kidney disease with (letter), 32

unilateral nephrectomy and, 107 Glucose reabsorption, renal hypertrophy and, 7 Glycemic control, see Blood glucose control;

Metabolic control

H

Hemodialysis centers, attendance of diabetic patients at, in Central Italy, 4

Hydroflumethiazide, renal function and, 45 Hyperglycemia, nephropathy progression and, 53 Hypertension, see a lso Blood pressure

nephropathy progression and, 53 treatment of, renal function and, 45

I

Immunofluorescence staining, double, glomerular sialic acids and, 61

Insulin, intraperitoneal, CAPD patients given, decreasing insulin requirements in, 16

Insulin-dependent diabetes mellitus, see Type I diabetes

Insulin pump treatment and kidney function and size in IDDM patients, 91 and metabolic control in kidney transplanted insulin-

dependent diabetics, 81 Intercapillary glomerulosclerosis, adult polycystic

kidney disease with (letter), 32 Intraperitoneal insulin, subcutaneous insulin vs., CAPD

patients and, 16 Islet transplants, potential of, 115 Italy, Central, dialysis centers in, attendance of diabetic

patients at, 4

K

Kidney, see Nephropathy; Renal ent r ies

M

Metabolic control kidney transplant and, 81 microalbuminuria and, in maturity onset non-insulin-

dependent diabetes, 132 nephropathy progression and. 53

Metoprolol, renal function and, 45 Microalbuminuria, 132

detection of, 58 in insulin-dependent diabetes, 76

w

N

Nephrectomy, unilateral, diabetic glomerulosclerosis and, 107

Nephropathy Armanni-Ebstein lesion in, genesis of, 2 clinical pattern of, 87 dietary protein and, 37 end-stage, hemodialysis treatment for, in Central

Italy, 4 glomerular sialic acids in, 61

145

146 SUBJECT INDEX

incipient, albuminuria progression in, antihypertensive treatment and, 45

long-term survival and (letter), 33 normoglycemic, 30 pathogenesis of, glomerular filtration and, blood

rheology and, 137 prevention of, 35 progression of, relationship to metabolic control and

blood pressure of, 53 renal biopsy in diabetic with, necessity of, 1 retinopathy incidence and, in Type I diabetes, 96

Nephrotoxicity, of cyclosporine, 128 Non-insulin-dependent diabetes mellitus, s e e Type II

diabetes Normoglycemia, near, effects of, in Type I diabetes, 100 Normoglycemic diabetic nephropathy, 30 Normoglycemic diabetic retinopathy, 30

O

Obese Zucker rat model, of glomerular injury in Type II diabetes, 26

P

Pancreas transplant, renal function after, cyclosporine and, 128

Peritoneal dialysis, continuous ambulatory, s e e Continuous ambulatory peritoneal dialysis

Platelet reactivity, near normoglycemia and, in Type I diabetes, 100

Polycystic kidney disease, adult, with diabetic intercapillary glomerulosclerosis (letter), 32

Protein, dietary, nephropathy and, 37

R

Renal biopsy, necessity of, in nephropathic diabetic, 1 Renal corpuscles, new vessel formation in, advanced

diabetic glomerulopathy and, 122 Renal function

antihypertensive treatment and, 45 continuous subcutaneous insulin infusion and, 91 cyclosporine effect on, in non-uremic diabetic

recipients of pancreas transplants, 128 relationship to metabolic control and blood pressure

of, 53 Renal histopathology, correlation with duration of

diabetes and blood glucose control, 41 Renal hypertrophy, functional aspects of, 7 Renal res,ection, diabetic glomerulosclerosis and, 107 Renal transplant, metabolic control and, 81

Retinopathy clinical nephropathy association with, in Type I

diabetes, 96 normoglycemic, 30

Sialic acids, glomerular, 61 Solid phase enzyme immunoassay, microalbuminuria

detection with, 58

T

Transplant islet, potential of, 115 pancreas, renal function after, cyclosporine and, 128 renal, metabolic control and, 81

Type I diabetes advanced glomerulopathy in, new vessel formation in

renal corpuscles in, 122 antihypertensive treatment and, renal function and,

45 kidney function and size in, continuous subcutaneous

insulin infusion and, 91 kidney transplant and, metabolic control with, 81 microalbuminuria in, 76 near normoglycemia in, 100 nephropathy in

dietary protein and, 37 progression of, 53 -~

pancreas transplant in, cyclosporine effect on native renal function after, 128

Type II diabetes glomerular injury in, obese Zucker model of, 26 maturity onset, microalbuminuria in, 132 renal histopathology, duration of diabetes, and blood

glucose control in, 41 unilatera~ nephrectomy in, diabetic

glomerulosclerosis and, 107

U

Unilateral nephrectomy, diabetic glomerulosclerosis and, 107

Uremia, co-morbidity with, 73 Urinary albumin excretion

antihypertensive treatment and, 45 insulin-dependent diabetes and, 76 maturity onset non-insulin-dependent diabetes

and, 132 measurement of, 58

V

Vitrectomy, 120 V~n Willebrand factor, near normoglycemia and, in

Type I diabetes, 100