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1120
Table S1. Characteristics of adult female monozygotic (MZ) twi Twin ID F1 F1T1 27 23 3 F1 F1T2 27 23 3 F2 F2T1 27 20 11 F2 F2T2 27 21 11 F3 F3T1 23 21 0 F3 F3T2 23 23 0 F4 F4T1 23 26 0 F4 F4T2 23 23 0 F5 F5T1 27 21 932 F5 F5T2 27 21 932 F6 F6T1 31 21 1926 F6 F6T2 31 20 1926 F7 F7T1 32 24 770 F7 F7T2 32 21 770 Family ID Age at enrollment (years) BMI at enrollment (kg/m 2 ) Physical distance between co- twins (miles) 1 NA = breastfeeding data not available

Transcript of stm.sciencemag.orgstm.sciencemag.org/content/scitransmed/s… · XLS file · Web view ·...

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Table S1. Characteristics of adult female monozygotic (MZ) twins enrolled in study.

Twin ID

F1 F1T1 27 23 3 NoF1 F1T2 27 23 3 NoF2 F2T1 27 20 11 NAF2 F2T2 27 21 11 NAF3 F3T1 23 21 0 NAF3 F3T2 23 23 0 NAF4 F4T1 23 26 0 NAF4 F4T2 23 23 0 NAF5 F5T1 27 21 932 Yes (2 months)F5 F5T2 27 21 932 Yes (2 months)F6 F6T1 31 21 1926 NAF6 F6T2 31 20 1926 NAF7 F7T1 32 24 770 NAF7 F7T2 32 21 770 NA

Family ID

Age at enrollment (years)

BMI at enrollment

(kg/m2)

Physical distance between co-twins

(miles)Breastfed, Y/N

(length)1

1NA = breastfeeding data not available

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27 strawberry, 9 peach27 strawberry, 9 vanilla12 strawberry, 12 peach, 12 vanilla12 strawberry, 12 peach, 12 vanilla12 strawberry, 12 peach, 12 vanilla12 strawberry, 12 peach, 12 vanilla18 strawberry, 18 peach18 strawberry, 18 peach36 peach18 peach, 18 strawberry36 vanilla12 strawberry, 12 peach, 12 vanilla12 strawberry, 12 peach, 12 vanilla18 strawberry, 18 vanilla

Fermented milk product flavor(s) selected (4 shipments)

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Table S2. Summary of human fecal metagenomic data sets.

A. Multiplex pyrosequencing of fecal bacterial 16S rRNA V2 amplicons.Sample designation is as follows: F=Family ID, T=co-twin ID (1 or 2), Pre4=4 weeks prior to FMP consumption, FMP2=2 weeks into FMP consumption, Post4=4 weeks after cessation of FMP consumption.

Sample Barcode Sequence

F1T1FMP1 AGTGTCACGGTG 7141F1T1FMP2 CATGTAATGCTC 2459F1T1FMP4 CATATCGCAGTT 2689F1T1FMP7 AGTTCAGACGCT 2383F1T1Post2 AGTTCTACGTCA 2697F1T1Post4 ATAATCTCGTCG 2669F1T1Pre1 AGTGGATGCTCT 1869F1T1Pre2 AGTGCGATGCGT 2838F1T1Pre4 AGTGAGAGAAGC 2992F1T2FMP1 ATAGGCGATCTC 2888F1T2FMP2 ATATCGCTACTG 2196F1T2FMP4 CAGCTAGAACGC 2635F1T2FMP7 ATCACGTAGCGG 3471F1T2Post2 ATCACTAGTCAC 2632F1T2Post4 GATAGTGCCACT 3032F1T2Pre1 CGATGCACCAGA 2318F1T2Pre2 ATACTCACTCAG 2750F1T2Pre4 ATACTATTGCGC 3021F2T1FMP1 CGGCGATGTACA 2640F2T1FMP2 ATCTCTGGCATA 2379F2T1FMP4 CACTCAACAGAC 3772F2T1FMP7 ATCTGGTGCTAT 2342F2T1Post2 ATCTTAGACTGC 2588F2T1Post4 ATGACCATCGTG 1705F2T1Pre1 ATCGTACAACTC 2509F2T1Pre2 ATCGCTCGAGGA 2402F2T1Pre4 ATCGCGGACGAT 2352F2T2FMP1 CGTGATCTCTCC 5860F2T2FMP2 ATGGATACGCTC 2433F2T2FMP4 CAAGATCGACTC 3321F2T2FMP7 CTACTGATATCG 2954F2T2Post2 ATGGTCTACTAC 2678F2T2Post4 ATGTACGGCGAC 2446

Number of 16S rRNA sequences

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F2T2Pre1 ATGCCTGAGCAG 2495F2T2Pre2 ATGCAGCTCAGT 2465F2T2Pre4 ATGCACTGGCGA 3470F3T1FMP1 CAACTATCAGCT 2575F3T1FMP2 CTCATGTACAGT 3037F3T1FMP4 GAGATGCCGACT 5723F3T1FMP7 CAAGTGAGAGAG 2624F3T1Post2 CACACGTGAGCA 2189F3T1Post4 CACAGCTCGAAT 2850F3T1Pre1 CAACACGCACGA 2852F3T1Pre2 CTGAGATACGCG 7378F3T1Pre4 ATTATCGTGCAC 2491F3T2FMP1 CACGTGACATGT 2628F3T2FMP2 CATGTCTCTCCG 7791F3T2FMP4 ATCTGAGCTGGT 2923F3T2FMP7 CACTCTGATTAG 2895F3T2Post2 CACTGGTATATC 2842F3T2Post4 GATGTGAGCGCT 2545F3T2Pre1 CACGTCGATGGA 2891F3T2Pre2 CACGGACTATAC 2819F3T2Pre4 CACGACAGGCTA 2683F4T1FMP1 CGACAGCTGACA 2824F4T1FMP2 CAGCGGTGACAT 2146F4T1FMP4 ATATGCCAGTGC 2616F4T1FMP7 CAGGTGCTACTA 2078F4T1Post2 CAGTACGATCTT 2618F4T1Post4 CAGTCACTAACG 4127F4T1Pre1 CAGCACTAAGCG 2460F4T1Pre2 CGATGTCGTCAA 2650F4T1Pre4 CAGATACACTTC 2486F4T2FMP1 CATAGCGAGTTC 3082F4T2FMP2 CATATACTCGCA 2599F4T2FMP4 CGAATCGACACT 6595F4T2FMP7 CATCAGCGTGTA 2759F4T2Post2 CATCATGAGGCT 2385F4T2Post4 CATCGTATCAAC 2419F4T2Pre1 CGTAAGTCTACT 6754F4T2Pre2 CGTGCATTATCA 6693F4T2Pre4 GACACTCGAATC 2279F5T1FMP1 ATGTCACCGTGA 2507F5T1FMP2 CACAGTGGACGT 2423

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F5T1FMP4 CAGACATTGCGT 2659F5T1FMP7 CAGTCGAAGCTG 1944F5T1Post2 CATCTGTAGCGA 2785F5T1Post4 CTGTTCGTAGAG 2241F5T1Pre1 ATGACTCATTCG 2369F5T1Pre2 ATCCGATCACAG 2423F5T1Pre4 ATACACGTGGCG 2355F5T2FMP1 CTAGAACGCACT 5888F5T2FMP2 GATCCGACACTA 2697F5T2FMP4 GCACATCGAGCA 2750F5T2FMP7 GCATCGTCAACA 2858F5T2Post2 GCGTTACACACA 2715F5T2Post4 CTTGATGCGTAT 2734F5T2Pre1 GACTCGAATCGT 2535F5T2Pre2 GACAGTTACTGC 2409F5T2Pre4 CTTAGCACATCA 2530F6T1FMP1 CTCCACATGAGA 6639F6T1FMP2 CTGAGCAGAGTC 26252F6T1FMP4 GCATGTGCATGT 2332F6T1FMP7 GCTAAGAGAGTA 2941F6T1Post2 CTTGTGTCGATA 7042F6T1Post4 GACCACTACGAT 2639F6T1Pre1 GAGGCTCATCAT 2948F6T1Pre2 GACTGATCATCT 2816F6T1Pre4 GACATCGGCTAT 2638F6T2FMP1 CATGGCTACACA 7935F6T2FMP2 GCATTGCGTGAG 2599F6T2FMP4 CGAAGACTGCTG 5210F6T2FMP7 ATCGATCTGTGG 2037F6T2Post2 ATGATCGAGAGA 2298F6T2Post4 ATGTGTCGACTT 2436F6T2Pre1 CGATCGAGTGTT 12510F6T2Pre2 GAGTAGCTCGTG 1948F6T2Pre4 GACTGCATCTTA 2652F7T1FMP1 ATGTGCACGACT 2087F7T1FMP2 CACATCTAACAC 1892F7T1FMP4 CGGAGTGTCTAT 5110F7T1FMP7 CATGAGTGCTAC 2333F7T1Post2 CAGACTCGCAGA 2066F7T1Post4 CGTGACAATGTC 7970F7T1Pre1 ATGAGACTCCAC 2595

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F7T1Pre2 ATCCTCAGTAGT 2462F7T1Pre4 ATACAGAGCTCC 2375F7T2FMP1 GACTCACTCAAT 2695F7T2FMP2 CTACTACAGGTG 6656F7T2FMP4 GACCGAGCTATG 3173F7T2FMP7 CTCAGTATGCAG 7838F7T2Post2 CAGTGCATATGC 2312F7T2Post4 CATGCAGACTGT 2406F7T2Pre1 CAGAGGAGCTCT 2665F7T2Pre2 CACATTGTGAGC 2620F7T2Pre4 GACAGGAGATAG 2954

* B1234=FMP batches 1,2,3,4; B3456=FMP batches 3,4,5,6

B. Multiplex shotgun pyrosequencing of total fecal community DNA.

Sample

F1T1FMP4 75249 65574F1T1FMP7 55067 47963F1T1Post2 47239 41715F1T1Post4 42824 37301F1T1Pre1 45636 39910F1T1Pre4 48736 42450F1T2FMP4 46098 40093F1T2FMP7 54286 47471F1T2Post2 43826 38725F1T2Post4 57918 50959F1T2Pre1 59486 52254F1T2Pre4 64157 55886F3T1FMP4 67697 57408F3T1FMP7 68496 57811F3T1Post2 30188 26388F3T1Post4 63158 53287F3T1Pre1 49246 41765F3T1Pre4 63488 53593F3T2FMP4 57136 48173F3T2FMP7 67237 56925F3T2Post2 62660 52689F3T2Post4 64193 53538

Number of Shotgun Reads

Number of Filtered Reads*

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F3T2Pre1 52681 45020F3T2Pre4 59866 50473F4T1FMP4 63758 50210F4T1FMP7 55671 43728F4T1Post2 46447 35815F4T1Post4 44105 34134F4T1Pre1 46610 39617F4T1Pre4 61274 50261F4T2FMP4 45720 38928F4T2FMP7 44513 35448F4T2Post2 35497 27596F4T2Post4 64160 48809F4T2Pre1 32380 25396F4T2Pre4 57289 50679F5T1FMP4 35261 33254F5T1FMP7 68995 65919F5T1Post2 47394 44885F5T1Post4 58502 49499F5T1Pre1 62935 57038F5T1Pre4 56065 50262F5T2FMP4 70374 61573F5T2FMP7 149079 129330F5T2Post2 83963 71274F5T2Post4 212675 184097F5T2Pre1 46874 44073F5T2Pre4 85328 72400

* Sequences used after removing poor quality, duplicate and human sequences

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Table S2. Summary of human fecal metagenomic data sets.

A. Multiplex pyrosequencing of fecal bacterial 16S rRNA V2 amplicons.Sample designation is as follows: F=Family ID, T=co-twin ID (1 or 2), Pre4=4 weeks prior to FMP consumption, FMP2=2 weeks into FMP consumption, Post4=4 weeks after cessation of FMP consumption.

FMP Batch*

TCGAGCGAATCT 12185 B1234TCGTTCACATGA 9295 B1234TCTGCTAGATGT 10265 B1234TGAGGATGATAG 10756 B1234TGCGTGGTAGAC 12345 NATATCTCGAACTG 5278 NATCATCGCGATAT 11458 NATCACGATTAGCG 10985 NATAGTTGCGAGTC 12168 NATCGAGGACTGCA 11919 B1234TCTACGGAGAGC 12271 B1234TCTGTTGCTCTC 12257 B1234TGAGTCACTGGT 10817 B1234TGCTACCATGAG 14486 NATCAGACAGACCG 10297 NATCATCTGACTGA 7649 NATCACTATGGTCA 10993 NATATACGCGCATT 11785 NA

B1234B1234B1234B1234

NANANANANA

B1234B1234B1234B1234

NANA

Barcode sequence used in the deep sequencing of 2 families

Number of 16S rRNA sequences for deep sequencing

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NANANA

B1234B1234B1234B1234

NANANANANA

B1234B1234B1234B1234

NANANANANA

B3456B3456B3456B3456

NANANANANA

B3456B3456B3456B3456

NANANANANA

TCGATACTTGTG 11501 B3456TCTACTCGTAAG 11977 B3456

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TCTTAGACGACG 10997 B3456TGAGTTCGCTAT 12226 B3456TGCTAGTCATAC 11645 NATCCAGTGCGAGA 13324 NATCATGGTACACT 12299 NATCACTGGCAGTA 11973 NATATCAGGTGTGC 15943 NATCGATGAACTCG 12545 B3456TCTAGCGTAGTG 11339 B3456TGATGTGTGACC 11556 B3456TGATAGTGAGGA 12282 B3456TGCTATATCTGG 11091 NATCGCATGAAGTC 12849 NATCCACGTCGTCT 9673 NATCACTTCTCGCT 8453 NATATCGCGCGATA 12295 NA

B3456B3456B3456B3456

NANANANANA

B3456B3456B3456B3456

NANANANANA

B3456B3456B3456B3456

NANANA

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NANA

B3456B3456B3456B3456

NANANANANA

* B1234=FMP batches 1,2,3,4; B3456=FMP batches 3,4,5,6

B. Multiplex shotgun pyrosequencing of total fecal community DNA.

Time Point

4 weeks into FMP consumption7 weeks into FMP consumption2 weeks after cessation of FMP consumption4 weeks after cessation of FMP consumption1 week before start of FMP consumption4 weeks before start of FMP consumption4 weeks into FMP consumption7 weeks into FMP consumption2 weeks after cessation of FMP consumption4 weeks after cessation of FMP consumption1 week before start of FMP consumption4 weeks before start of FMP consumption4 weeks into FMP consumption7 weeks into FMP consumption2 weeks after cessation of FMP consumption4 weeks after cessation of FMP consumption1 week before start of FMP consumption4 weeks before start of FMP consumption4 weeks into FMP consumption7 weeks into FMP consumption2 weeks after cessation of FMP consumption4 weeks after cessation of FMP consumption

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1 week before start of FMP consumption4 weeks before start of FMP consumption4 weeks into FMP consumption7 weeks into FMP consumption2 weeks after cessation of FMP consumption4 weeks after cessation of FMP consumption1 week before start of FMP consumption4 weeks before start of FMP consumption4 weeks into FMP consumption7 weeks into FMP consumption2 weeks after cessation of FMP consumption4 weeks after cessation of FMP consumption1 week before start of FMP consumption4 weeks before start of FMP consumption4 weeks into FMP consumption7 weeks into FMP consumption2 weeks after cessation of FMP consumption4 weeks after cessation of FMP consumption1 week before start of FMP consumption4 weeks before start of FMP consumption4 weeks into FMP consumption7 weeks into FMP consumption2 weeks after cessation of FMP consumption4 weeks after cessation of FMP consumption1 week before start of FMP consumption4 weeks before start of FMP consumption

* Sequences used after removing poor quality, duplicate and human sequences

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Sample designation is as follows: F=Family ID, T=co-twin ID (1 or 2), Pre4=4 weeks prior to FMP consumption, FMP2=2 weeks into FMP consumption, Post4=4 weeks after cessation of FMP consumption.

Time Point

1 week into FMP consumption2 weeks into FMP consumption4 weeks into FMP consumption7 weeks into FMP consumption2 weeks after cessation of FMP consumption4 weeks after cessation of FMP consumption1 week before start of FMP consumption2 weeks before start of FMP consumption4 weeks before start of FMP consumption1 week into FMP consumption2 weeks into FMP consumption4 weeks into FMP consumption7 weeks into FMP consumption2 weeks after cessation of FMP consumption4 weeks after cessation of FMP consumption1 week before start of FMP consumption2 weeks before start of FMP consumption4 weeks before start of FMP consumption1 week into FMP consumption2 weeks into FMP consumption4 weeks into FMP consumption7 weeks into FMP consumption2 weeks after cessation of FMP consumption4 weeks after cessation of FMP consumption1 week before start of FMP consumption2 weeks before start of FMP consumption4 weeks before start of FMP consumption1 week into FMP consumption2 weeks into FMP consumption4 weeks into FMP consumption7 weeks into FMP consumption2 weeks after cessation of FMP consumption4 weeks after cessation of FMP consumption

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1 week before start of FMP consumption2 weeks before start of FMP consumption4 weeks before start of FMP consumption1 week into FMP consumption2 weeks into FMP consumption4 weeks into FMP consumption7 weeks into FMP consumption2 weeks after cessation of FMP consumption4 weeks after cessation of FMP consumption1 week before start of FMP consumption2 weeks before start of FMP consumption4 weeks before start of FMP consumption1 week into FMP consumption2 weeks into FMP consumption4 weeks into FMP consumption7 weeks into FMP consumption2 weeks after cessation of FMP consumption4 weeks after cessation of FMP consumption1 week before start of FMP consumption2 weeks before start of FMP consumption4 weeks before start of FMP consumption1 week into FMP consumption2 weeks into FMP consumption4 weeks into FMP consumption7 weeks into FMP consumption2 weeks after cessation of FMP consumption4 weeks after cessation of FMP consumption1 week before start of FMP consumption2 weeks before start of FMP consumption4 weeks before start of FMP consumption1 week into FMP consumption2 weeks into FMP consumption4 weeks into FMP consumption7 weeks into FMP consumption2 weeks after cessation of FMP consumption4 weeks after cessation of FMP consumption1 week before start of FMP consumption2 weeks before start of FMP consumption4 weeks before start of FMP consumption1 week into FMP consumption2 weeks into FMP consumption

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4 weeks into FMP consumption7 weeks into FMP consumption2 weeks after cessation of FMP consumption4 weeks after cessation of FMP consumption1 week before start of FMP consumption2 weeks before start of FMP consumption4 weeks before start of FMP consumption1 week into FMP consumption2 weeks into FMP consumption4 weeks into FMP consumption7 weeks into FMP consumption2 weeks after cessation of FMP consumption4 weeks after cessation of FMP consumption1 week before start of FMP consumption2 weeks before start of FMP consumption4 weeks before start of FMP consumption1 week into FMP consumption2 weeks into FMP consumption4 weeks into FMP consumption7 weeks into FMP consumption2 weeks after cessation of FMP consumption4 weeks after cessation of FMP consumption1 week before start of FMP consumption2 weeks before start of FMP consumption4 weeks before start of FMP consumption1 week into FMP consumption2 weeks into FMP consumption4 weeks into FMP consumption7 weeks into FMP consumption2 weeks after cessation of FMP consumption4 weeks after cessation of FMP consumption1 week before start of FMP consumption2 weeks before start of FMP consumption4 weeks before start of FMP consumption1 week into FMP consumption2 weeks into FMP consumption4 weeks into FMP consumption7 weeks into FMP consumption2 weeks after cessation of FMP consumption4 weeks after cessation of FMP consumption1 week before start of FMP consumption

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2 weeks before start of FMP consumption4 weeks before start of FMP consumption1 week into FMP consumption2 weeks into FMP consumption4 weeks into FMP consumption7 weeks into FMP consumption2 weeks after cessation of FMP consumption4 weeks after cessation of FMP consumption1 week before start of FMP consumption2 weeks before start of FMP consumption4 weeks before start of FMP consumption

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Table S3. Features of the microbial genomes in the 5-member FMP strain consortium and the 15-member model human gut microbiota.

Bacterium PhylumM

odel

Hum

an G

ut M

icro

biot

a

Bacteroides caccae BacteroidetesBacteroides ovatus BacteroidetesBacteroides thetaiotaomicron* BacteroidetesBacteroides uniformis BacteroidetesBacteroides vulgatus BacteroidetesBacteroides WH2 BacteroidetesClostridium scindens FirmicutesClostridium spiroforme FirmicutesCollinsella aerofaciens ActinobacteriaDorea longicatena FirmicutesEubacterium rectale FirmicutesFaecalibacterium prausnitzii FirmicutesParabacteroides distasonis BacteroidetesRuminococcus obeum FirmicutesRuminococcus torques Firmicutes

* Represents a library of IN-seq transposon mutants

Bacterium Phylum

ActinobacteriaFirmicutesFirmicutesFirmicutes

Streptococcus thermophilus FirmicutesFerm

ente

d M

ilk P

rodu

ct

Cons

ortiu

m

Bifidobacterium animalis subsp. lactisLactobacillus delbrueckii subsp. bulgaricusLactobacillus delbrueckii subsp. bulgaricusLactococcus lactis subsp. cremoris

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Table S3. Features of the microbial genomes in the 5-member FMP strain consortium and the 15-member model human gut microbiota.

Culture Collection ID GenBank Accession Genome Status

ATCC 43185 411901 AAVM00000000.2 Draft 4564814ATCC 8483 411476 AAXF00000000.2 Draft 6463169VPI-5482 226186 AE015928.1 Complete 6260361ATCC 8492 411479 AAYH00000000.2 Draft 4717497ATCC 8482 435590 CP000139.1 Complete 5163189N/A N/A N/A Complete 7129681ATCC 35704 411468 ABFY00000000.2 Draft 3619905DSM 1552 428126 ABIK00000000.2 Draft 2507485ATCC 25986 411903 AAVN00000000.2 Draft 2439869DSM 13814 411462 AAXB00000000.2 Draft 2913833ATCC 33656 515619 CP001107.1 Complete 3449685M21/2 411485 ABED00000000.2 Draft 3126983ATCC 8503 435591 CP000140.1 Complete 4811379ATCC 29174 411459 AAVO00000000.2 Draft 3624708ATCC 27756 411460 AAVP00000000.2 Draft 2739406

Culture Collection ID Alternative ID GenBank Accession Genome Status

CNCM I-2494 DN-173 010 CP002915.1 Complete 1943113CNCM I-1632 DN-100 130 AGFO00000000 Draft 1767897CNCM I-1519 DN-100 182 AGHW00000000 Draft 1795730CNCM I-1631 DN-030 066 AGHX00000000 Draft 2511332CNCM I-1630 DN-001 171 AGFN00000000 Draft 1621848

Taxonomy ID(NCBI)

Genome Size (bases)

Genome Size (bases)

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# CDS

3855 2077 53.9%5536 2628 47.5%4778 2575 53.9%4663 2171 46.6%4065 2774 68.2%5691 2810 49.4%3995 2268 56.8%2465 1619 65.7%2367 1426 60.2%2970 1878 63.2%3621 1953 53.9%3493 1676 48.0%3850 2274 59.1%4175 2166 51.9%2875 1558 54.2%

# CDS Sequenced By

1660 1095 66.0% Integrated Genomics1850 1243 67.2% Washington University1893 1238 65.4% Washington University2579 1571 60.9% Washington University1892 1461 77.2% Integrated Genomics

# CDS with Assignable Function

(KEGG v54)

% CDS with Assignable Function

# CDS with Assignable Function

(KEGG v54)

% CDS with Assignable Function

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Sequencing Platform Assembly Method # Contigs

Sanger (ABI 3700) Phred-Phrap-Consed 1454 (GS FLX Standard) 69454 (GS FLX Standard) 70454 (GS FLX Standard) 131Sanger (ABI 3700) Phred-Phrap-Consed 376

Newbler, de novo (v1.1)Newbler, de novo (v1.1)Newbler, de novo (v1.1)

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Average Contig Size (bp) Coverage

N/A N/A N/A 13.6X (Sanger)25622 69466 246844 32.5X25665 55626 263365 31.6X19170 55851 185745 51X4295 8495 30335 6.5X

N50 Contig

Size (bp)Max Contig Size

(bp)

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Table S4. Carbohydrate-active enzyme (CAZy) annotation data.

A. CAZy summaries by genome.

Open reading frame (ORF) counts by genome

CAZyme counts by genome

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Glycoside hydrolase (GH) family counts

Polysaccharide lyase (PL) family counts

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Carbohydrate esterase (CE) family counts

Carbohydrate-binding module (CBM) family counts

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B. CAZy annotations for the 20 bacterial species in this study.

ORF Name CAZy module(s)

Glycosyltransferase (GT) family counts

Bacteroides caccae (ATCC 43185)

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BACCAC_00013 GH2BACCAC_00014 GH105BACCAC_00020 GH88BACCAC_00021 GH43-GH106BACCAC_00049 GH16BACCAC_00062 GH31BACCAC_00071 GH97BACCAC_00084 GH29BACCAC_00111 CBM32BACCAC_00112 GH110BACCAC_00113 GH95BACCAC_00171 GH123BACCAC_00175 GT30BACCAC_00253 PL9BACCAC_00254 PL9BACCAC_00255 GH89BACCAC_00256 GH109BACCAC_00257 GH35-CBM32BACCAC_00278 GH27-CBM35BACCAC_00302 GH16BACCAC_00337 GT51BACCAC_00349 GH3BACCAC_00371 GT3BACCAC_00372 GT35BACCAC_00459 GT4BACCAC_00462 GT6BACCAC_00463 GT11BACCAC_00464 GT2BACCAC_00486 GH92BACCAC_00584 GH29BACCAC_00667 GH13BACCAC_00669 CBM48-GH13BACCAC_00685 GT51BACCAC_00692 GT2BACCAC_00694 GT4BACCAC_00695 GT4BACCAC_00698 GT4BACCAC_00699 GT2BACCAC_00706 GT2BACCAC_00820 GH97BACCAC_00821 CE9

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BACCAC_00822 CE9BACCAC_00904 GT4BACCAC_00905 GT4BACCAC_00907 GT2BACCAC_00908 GT2BACCAC_00911 GT4BACCAC_01003 GT2BACCAC_01004 GT2BACCAC_01005 GT4BACCAC_01014 GT4BACCAC_01018 GT4BACCAC_01019 GT2BACCAC_01021 GT2BACCAC_01033 GT51BACCAC_01084 GH20-CBM32BACCAC_01085 GH20-CBM32BACCAC_01086 GH2BACCAC_01089 GH20BACCAC_01090 GH33BACCAC_01227 GT2BACCAC_01233 GT4BACCAC_01234 GT4BACCAC_01235 GT2BACCAC_01241 GH105BACCAC_01242 GH31-CBM32BACCAC_01244 GH2BACCAC_01249 GH2BACCAC_01250 GH29BACCAC_01270 GH30BACCAC_01310 GH3BACCAC_01322 GH2BACCAC_01323 GH105BACCAC_01335 GH88BACCAC_01336 GH95BACCAC_01339 GH29BACCAC_01347 GH29BACCAC_01367 CBM32BACCAC_01368 CBM32BACCAC_01369 GH36BACCAC_01370 GH31BACCAC_01371 GH2

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BACCAC_01383 GH95BACCAC_01386 GH31-CBM32BACCAC_01443 CE4BACCAC_01492 GH88BACCAC_01498 GH109BACCAC_01509 PL8BACCAC_01526 GH2BACCAC_01536 GH88BACCAC_01538 PL8BACCAC_01554 GT9BACCAC_01559 GT4BACCAC_01563 GT2BACCAC_01564 GT2BACCAC_01565 GT2BACCAC_01567 GT2BACCAC_01569 GT4BACCAC_01571 GT2BACCAC_01572 GT32BACCAC_01573 GT8BACCAC_01577 GT2BACCAC_01579 GT2BACCAC_01590 GT2BACCAC_01591 GT83BACCAC_01682 GH92BACCAC_01684 GH92BACCAC_01687 GH92BACCAC_01692 GH23BACCAC_01697 GT19BACCAC_01713 GH2-CBM32BACCAC_01747 GH105BACCAC_01748 CE8BACCAC_01750 CE12-CE8BACCAC_01750 CE12-CE8BACCAC_01755 PL1BACCAC_01756 PL1BACCAC_01778 CBM32BACCAC_01779 GH35BACCAC_01780 GH43BACCAC_01782 CBM32BACCAC_01783 GH2BACCAC_01784 GH120

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BACCAC_01785 GH95BACCAC_01787 GH43BACCAC_01789 GH28BACCAC_01806 CE11BACCAC_01836 GH2BACCAC_01839 GH109BACCAC_01840 CBM32BACCAC_01841 CBM32BACCAC_01842 CBM32BACCAC_01849 CBM32BACCAC_01850 CBM32BACCAC_01853 GH110BACCAC_01858 CBM32BACCAC_01859 CBM32BACCAC_01861 GH109BACCAC_01892 GT4BACCAC_01893 GH57BACCAC_01895 GT5BACCAC_01921 GH88BACCAC_01971 GH35BACCAC_01972 GH89BACCAC_02026 GT2BACCAC_02088 GH2BACCAC_02089 GH53BACCAC_02114 GH123BACCAC_02115 GH88BACCAC_02168 CE1BACCAC_02176 GT51BACCAC_02179 GH116BACCAC_02191 GH23BACCAC_02226 CBM32BACCAC_02249 GT2BACCAC_02276 GH25BACCAC_02306 GH51BACCAC_02384 PL8BACCAC_02388 GT2BACCAC_02402 GH33BACCAC_02407 GH33BACCAC_02529 GH89BACCAC_02539 GT2BACCAC_02540 GT2

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BACCAC_02544 GT11BACCAC_02545 GT2BACCAC_02574 CBM32BACCAC_02606 GT20BACCAC_02614 PL9BACCAC_02615 GH2BACCAC_02659 GT2BACCAC_02661 GH29BACCAC_02668 GH3BACCAC_02679 GH16BACCAC_02680 GH16BACCAC_02711 GH29-CBM32BACCAC_02726 GH32BACCAC_02729 GH91BACCAC_02730 GH91BACCAC_02731 GH32BACCAC_02807 GH20BACCAC_02808 GH35BACCAC_02818 GH78BACCAC_02819 GH20BACCAC_02820 GH78BACCAC_02824 GH3BACCAC_02832 CBM48-GH13BACCAC_02845 GH20BACCAC_02846 GH2BACCAC_02847 GH29-CBM32BACCAC_02896 GH2BACCAC_02897 CBM32BACCAC_02898 CBM32BACCAC_02929 GH73-CBM50-CBM50BACCAC_03041 GT2BACCAC_03044 CBM20-CBM20-GH77BACCAC_03089 GT4BACCAC_03208 GT2BACCAC_03210 GH29BACCAC_03226 GH35-CBM32BACCAC_03226 GH35-CBM32BACCAC_03227 GH43BACCAC_03228 GH51BACCAC_03229 GH97BACCAC_03230 GH43

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BACCAC_03236 CBM32BACCAC_03237 GH16BACCAC_03238 GH16-GH43BACCAC_03240 GH43BACCAC_03242 GH105BACCAC_03251 GT2BACCAC_03308 PL8BACCAC_03332 GH29BACCAC_03389 GH20BACCAC_03474 CBM32BACCAC_03475 GH36BACCAC_03506 GT28BACCAC_03555 GH3BACCAC_03594 GH20BACCAC_03595 GH84BACCAC_03598 GH2BACCAC_03604 GH3BACCAC_03614 GH3BACCAC_03615 GH43-CBM6BACCAC_03616 GH29BACCAC_03645 GH20BACCAC_03660 GH3BACCAC_03661 GH28BACCAC_03662 GH20BACCAC_03663 GH28BACCAC_03717 GH16BACCAC_03741 GH20BACCAC_03747 GH20BACCAC_03750 GH3BACCAC_03751 GH3BACCAC_03767 GH92BACCAC_03777 GH97BACCAC_03841 GH29BACCAC_03890 GH2BACCAC_03893 GH23

ORF Name CAZy module(s)BACOVA_00033 GH28BACOVA_00044 GH27BACOVA_00045 PL9

Bacteroides ovatus (ATCC 8483)

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BACOVA_00046 GH10BACOVA_00047 GH43BACOVA_00048 GH115BACOVA_00053 GH43BACOVA_00054 GH29-CBM32BACOVA_00079 GT3BACOVA_00080 GT35BACOVA_00104 GH20BACOVA_00120 GH27-CBM35BACOVA_00151 CE4BACOVA_00159 GH18BACOVA_00164 GH106BACOVA_00181 GH2BACOVA_00182 GH2BACOVA_00184 GH2-CBM57BACOVA_00227 GH43BACOVA_00228 + BACOVA_00 GH2BACOVA_00247 GH10-GH10BACOVA_00249 GH115BACOVA_00250 GH2BACOVA_00256 GH97BACOVA_00257 GH43-CBM6BACOVA_00258 CE6-GH95BACOVA_00259 GH43BACOVA_00260 GH3BACOVA_00261 GH67BACOVA_00285 GH78BACOVA_00354 GH20BACOVA_00400 GT2BACOVA_00426 GH3BACOVA_00427 GH3BACOVA_00487 GH43BACOVA_00488 GH10BACOVA_00490 GH97BACOVA_00492 GH115BACOVA_00494 GH43-CBM6BACOVA_00495 GH2BACOVA_00496 GH2BACOVA_00497 GH97BACOVA_00500 GH31BACOVA_00501 GH2

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BACOVA_00502 GH31BACOVA_00559 GH20BACOVA_00560 GH20BACOVA_00562 GH2BACOVA_00563 GH33BACOVA_00568 GT11BACOVA_00569 GT2BACOVA_00570 GT4BACOVA_00573 GT26BACOVA_00624 GH16BACOVA_00625 GH16-GH3BACOVA_00786 PL1BACOVA_00788 GH2BACOVA_00837 GH2BACOVA_00901 GH78BACOVA_00906 GH125BACOVA_00907 GH76BACOVA_00940 GH20BACOVA_00944 GH30BACOVA_00946 GH3BACOVA_00965 GT2BACOVA_00969 PL8BACOVA_00977 CBM35BACOVA_00980 CE12-CE4BACOVA_00981 GH43BACOVA_00982 GH115BACOVA_01057 GT30BACOVA_01061 GH123BACOVA_01137 GH89BACOVA_01177 GT2BACOVA_01182 CE4BACOVA_01214 GH31BACOVA_01215 GH76BACOVA_01216 CBM32BACOVA_01221 GH31BACOVA_01222 GH92BACOVA_01223 GH92BACOVA_01256 GH23BACOVA_01276 GT51BACOVA_01285 CE1BACOVA_01292 GH88

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BACOVA_01293 GH43BACOVA_01304 GH2BACOVA_01315 GH28BACOVA_01317 GH30BACOVA_01330 GH97BACOVA_01373 GH20BACOVA_01374 GH20BACOVA_01491 GH95BACOVA_01494 GH29-CBM32BACOVA_01495 CBM6-GH43BACOVA_01577 GH3BACOVA_01593 GT51BACOVA_01609 GH27BACOVA_01619 CE7BACOVA_01633 GH16BACOVA_01636 GH92BACOVA_01649 GH25BACOVA_01671 GH2BACOVA_01672 GH88BACOVA_01687 GH88-GH92BACOVA_01699 GH31BACOVA_01708 GH51BACOVA_01717 GH51BACOVA_01744 GT4BACOVA_01748 GT4BACOVA_01749 GT2BACOVA_01754 GT4BACOVA_01755 GT26BACOVA_01857 GT28BACOVA_01896 GH36BACOVA_01918 GT83BACOVA_01921 GT2BACOVA_01932 GT6BACOVA_01934 GT11BACOVA_01935 GT2BACOVA_01936 GT2BACOVA_01937 GT2BACOVA_01939 GT2BACOVA_01941 GT2BACOVA_01945 GT4BACOVA_01948 GT9

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BACOVA_01950 GT4BACOVA_01951 GT9BACOVA_01967 PL8BACOVA_01969 GH88BACOVA_01971 GH2BACOVA_01973 GH43BACOVA_01990 GH2BACOVA_02006 GH95BACOVA_02038 GH89BACOVA_02042 GH89BACOVA_02056 CE1BACOVA_02057 CE1BACOVA_02061 GH18BACOVA_02091 GH36BACOVA_02092 GH26BACOVA_02093 GH26BACOVA_02104 GH2BACOVA_02105 CE7BACOVA_02108 GH105BACOVA_02109 GH3BACOVA_02110 GH3BACOVA_02158 GH105BACOVA_02159 GH105BACOVA_02160 GH2BACOVA_02162 GH2BACOVA_02169 GH43BACOVA_02171 GH105BACOVA_02173 GH115BACOVA_02181 GH43BACOVA_02191 GT4BACOVA_02192 GT2BACOVA_02214 GT11BACOVA_02219 GT2BACOVA_02378 CE9BACOVA_02379 CE9BACOVA_02386 GH97BACOVA_02463 GT4BACOVA_02464 GT4BACOVA_02469 GT4BACOVA_02471 GT2BACOVA_02478 GT51

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BACOVA_02493 GH2BACOVA_02503 CBM48-GH13BACOVA_02505 GH13BACOVA_02626 GH5BACOVA_02630 GH5BACOVA_02631 GH2BACOVA_02632 GH5BACOVA_02636 GH78BACOVA_02644 GH3BACOVA_02645 GH2BACOVA_02646 GH31BACOVA_02649 GH9BACOVA_02653 GH5BACOVA_02654 GH43BACOVA_02656 GH43BACOVA_02659 GH3BACOVA_02661 GH30BACOVA_02662 GH43BACOVA_02668 GH18BACOVA_02692 GH2BACOVA_02693 CE12-CE12BACOVA_02699 GH106BACOVA_02702 PL11BACOVA_02710 GH2BACOVA_02711 GH88BACOVA_02714 GH28BACOVA_02715 GH95BACOVA_02717 GH2BACOVA_02718 GH105BACOVA_02719 PL11BACOVA_02738 GH3BACOVA_02741 GH16BACOVA_02745 GH3BACOVA_02753 GH3BACOVA_02767 GH97BACOVA_02769 GH3BACOVA_02770 GH2BACOVA_02777 GH115BACOVA_02783 GH31BACOVA_02784 GH66BACOVA_02795 GH2

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BACOVA_02797 GH43BACOVA_02799 GH51BACOVA_02806 GH43BACOVA_02826 GH92BACOVA_02833 GH78BACOVA_02863 GH88BACOVA_02942 GH92BACOVA_02949 GH5BACOVA_02950 GH20BACOVA_02956 GH43BACOVA_02958 GH3BACOVA_02959 GH97BACOVA_02974 GH15BACOVA_02975 GT20BACOVA_03088 PL10BACOVA_03100 GH2-CBM57BACOVA_03101 GH50BACOVA_03102 GH50BACOVA_03118 GH106BACOVA_03120 GH78BACOVA_03121 GH20BACOVA_03195 GT2BACOVA_03199 CBM20-CBM20-GH77BACOVA_03256 GH76BACOVA_03257 GH76BACOVA_03258 GH92BACOVA_03333 GH2BACOVA_03334 GH43BACOVA_03336 GH43BACOVA_03341 GH76BACOVA_03344 GH76BACOVA_03346 GH92BACOVA_03347 GH125BACOVA_03380 GH3BACOVA_03397 CE9BACOVA_03399 GH3BACOVA_03400 GH26BACOVA_03417 GH43BACOVA_03419 GH3BACOVA_03421 GH43BACOVA_03422 GH31

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BACOVA_03423 GH97BACOVA_03424 GH43-CBM6BACOVA_03425 GH43BACOVA_03431 GH10BACOVA_03432 GH30BACOVA_03433 GH98-CBM35BACOVA_03434 GH115BACOVA_03435 CE6-CE1BACOVA_03436 GH43-CBM6BACOVA_03438 GH95BACOVA_03449 GH115BACOVA_03457 GT2BACOVA_03481 GH35-CBM32BACOVA_03482 GH43BACOVA_03483 GH51BACOVA_03484 GH97BACOVA_03487 GH31BACOVA_03492 GH43BACOVA_03494 GH105BACOVA_03501 GT2BACOVA_03502 GH20BACOVA_03508 GH16BACOVA_03511 GH2BACOVA_03514 GH13BACOVA_03519 GH97BACOVA_03520 GH13BACOVA_03558 GH18BACOVA_03569 CE7BACOVA_03575 PL1BACOVA_03576 CE8BACOVA_03577 GH95BACOVA_03581 CE8BACOVA_03584 GH28BACOVA_03613 GH50BACOVA_03616 GH31BACOVA_03617 GH2-CBM57BACOVA_03618 CE6BACOVA_03623 GH92BACOVA_03626 GH125BACOVA_03627 GH76BACOVA_03629 GH92

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BACOVA_03633 GH76BACOVA_03639 GH36BACOVA_03640 GH29BACOVA_03674 GT6BACOVA_03675 GT2BACOVA_03733 GT4BACOVA_03736 GT4BACOVA_03810 GH20BACOVA_03980 GT51BACOVA_03991 GT2BACOVA_03993 GT2BACOVA_03994 GT4BACOVA_04011 GT4BACOVA_04012 GT2BACOVA_04013 GT2BACOVA_04097 GH18BACOVA_04105 GH18BACOVA_04111 GH92BACOVA_04117 PL1BACOVA_04119 GH43BACOVA_04121 GH78BACOVA_04122 GH28BACOVA_04126 GH78-GH33BACOVA_04128 GH105BACOVA_04129 GH95BACOVA_04181 GH3BACOVA_04184 GH33BACOVA_04188 GH33BACOVA_04203 GT2BACOVA_04276 GH73-CBM50-CBM50BACOVA_04357 GH29-CBM32BACOVA_04358 GH2BACOVA_04359 GH20BACOVA_04385 GH67BACOVA_04386 GH43BACOVA_04387 GH10BACOVA_04390 GH10-GH10BACOVA_04395 CBM48-GH13BACOVA_04477 PL12BACOVA_04482 GH29BACOVA_04484 GH88

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BACOVA_04501 GH32BACOVA_04502 GH91BACOVA_04503 GH91BACOVA_04507 GH32BACOVA_04535 GH29-CBM32BACOVA_04588 GH29BACOVA_04606 GH92BACOVA_04608 GH92-GH43BACOVA_04609 GH97BACOVA_04722 GH73BACOVA_04800 GH18BACOVA_04807 GH18BACOVA_04809 GH92BACOVA_04810 GH92BACOVA_04813 GH92BACOVA_04818 GH23BACOVA_04823 GT19BACOVA_04868 GH38BACOVA_04869 GH92BACOVA_04870 GH2-CBM32BACOVA_04872 GH78BACOVA_04874 GH31BACOVA_04883 GH92BACOVA_04884 GH92BACOVA_04900 GH105BACOVA_04901 CE8BACOVA_04902 CE12-CE8BACOVA_04905 PL1BACOVA_04906 PL1BACOVA_04907 PL1BACOVA_04908 CE8BACOVA_04916 PL1BACOVA_04920 PL1BACOVA_04925 CE8BACOVA_04926 GH28BACOVA_04927 GH3BACOVA_04929 GH43-CBM6BACOVA_04945 GH106BACOVA_04946 GH28BACOVA_04948 GH28BACOVA_04949 CE12

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BACOVA_04950 GH2BACOVA_04951 GH43-GH43-CBM32BACOVA_04952 GH42BACOVA_04954 GH28BACOVA_04966 PL11BACOVA_04972 CE12-CE12BACOVA_04973 GH105BACOVA_04974 PL11BACOVA_04975 GH105BACOVA_04978 CE4BACOVA_04979 GH105BACOVA_04983 CE12BACOVA_04992 GH2BACOVA_04995 PL11BACOVA_04997 GH28BACOVA_05000 PL9BACOVA_05002 GH28BACOVA_05005 PL1BACOVA_05015 GH28BACOVA_05031 GH105BACOVA_05037 GH43BACOVA_05040 GH28BACOVA_05053 CE11BACOVA_05079 GH2BACOVA_05082 GH109BACOVA_05083 GH109BACOVA_05104 GT4BACOVA_05105 GH57BACOVA_05107 GT5BACOVA_05141 GH20-CBM32BACOVA_05182 GH35BACOVA_05183 GH89BACOVA_05293 GH23BACOVA_05364 GT2BACOVA_05375 GH97BACOVA_05468 PL15BACOVA_05473 PL12BACOVA_05474 GH88BACOVA_05478 PL12BACOVA_05487 GH2BACOVA_05488 GH53

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BACOVA_05497 PL13BACOVA_05517 GT4BACOVA_05518 GT4BACOVA_05520 GT11BACOVA_05523 GT4BACOVA_05527 GT4BACOVA_05561 GH18BACOVA_05565 GH3BACOVA_05611 GH28BACOVA_05613 CBM6

ORF Name CAZy module(s)BT_0044 GT2BT_0046 GT2BT_0047 GT2BT_0050 GT2BT_0051 GT2BT_0053 GT4BT_0054 GT4BT_0055 GT4BT_0065 GH27BT_0127 GH28BT_0132 GH97BT_0145 GH43BT_0146 GH88BT_0152 CE1BT_0162 GT51BT_0183 GH23BT_0251 GT2BT_0264 GH43-CBM32BT_0265 GH43BT_0290 GH35-CBM32BT_0308 GH25BT_0339 GH31BT_0348 GH51BT_0360 GH43BT_0367 GH43BT_0368 GH51BT_0369 GH43BT_0391 GT4

Bacteroides thetaiotaomicron (VPI-5482)

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BT_0394 GT4BT_0438 GH89BT_0445 CE2BT_0455 GH33BT_0456 GH20BT_0458 GH2BT_0459 GH20-CBM32BT_0460 GH20BT_0461 GH2BT_0471 GT4BT_0473 GT2BT_0478 GT4BT_0479 GT2BT_0506 GH20BT_0608 GT4BT_0609 GT4BT_0610 GT4BT_0675 CE9BT_0676 CE9BT_0683 GH97BT_0743 GT51BT_0757 GH2BT_0771 CBM48-GH13BT_0773 GH13BT_0865 CBM32BT_0980 PL1BT_0983 GH2BT_0986 GH106BT_0992 GH2BT_0993 GH2BT_0996 GH2-CBM57BT_1001 GH78BT_1010 GH95BT_1011 GH105BT_1013 GH78-GH33BT_1018 GH28BT_1019 GH78BT_1021 GH43BT_1023 PL1BT_1032 GH92BT_1038 GH18

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BT_1044 GH18BT_1048 GH18BT_1051 GH20BT_1087 CE10BT_1100 GT35BT_1166 GT2BT_1167 GT2BT_1176 GT2BT_1180 GT4BT_1181 GT2BT_1183 GT2BT_1195 GT51BT_1284 GH18BT_1285 GH18BT_1293 GT35BT_1294 GT3BT_1340 GT2BT_1344 GT4BT_1347 GT2BT_1352 GT4BT_1353 GT2BT_1472 GT2BT_1538 GH73-CBM50-CBM50BT_1621 GH20BT_1625 GH29-CBM32BT_1626 GH2BT_1627 GH20BT_1632 GH18BT_1645 GT2BT_1646 GT2BT_1648 GT2BT_1649 GT25BT_1663 CBM48-GH13BT_1709 GT2BT_1712 GT4BT_1759 GH32BT_1760 GH32BT_1765 GH32BT_1768 GH2BT_1769 GH92BT_1776 GH2

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BT_1777 GH95BT_1778 GH3BT_1780 GH3BT_1781 GH43BT_1842 GH29BT_1871 GH97BT_1872 GH3BT_1873 GH43BT_1878 GH92BT_1883 GH76BT_2105 GH92BT_2111 GH92BT_2112 GH43BT_2146 CBM20-CBM20-GH77BT_2148 GT4BT_2151 GT2BT_2191 + BT_2190 GH2BT_2192 GH29BT_2194 CBM32BT_2199 GH92BT_2254 PL10BT_2378 GH28BT_2432 GH2BT_2439 GH3BT_2459 GH20BT_2501 GT51BT_2523 GH78BT_2524 GH78BT_2525 CE7BT_2550 GH16BT_2620 GH97BT_2622 GH67BT_2623 GH76BT_2629 GH92BT_2631 GH76BT_2632 GH125BT_2662 GH27BT_2680 GH2BT_2747 GT30BT_2751 GH123BT_2824 GH16

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BT_2825 GH18BT_2851 GH36BT_2852 GH43BT_2854 GH3BT_2855 GH2BT_2864 GT4BT_2865 GT4BT_2866 GT4BT_2868 GT2BT_2870 GT14BT_2871 GT14BT_2872 GT32BT_2873 GT8BT_2874 GT2BT_2876 GT2BT_2882 GT2BT_2892 GH93BT_2895 GH43BT_2898 GH43BT_2900 GH43BT_2912 GH43-GH106BT_2913 GH88BT_2921 GH105BT_2922 GH2BT_2936 GT4BT_2938 GT4BT_2946 GT4BT_2947 GT2BT_2948 GH92-GH92BT_2949 GH76BT_2958 GH115BT_2959 GH43BT_2963 GH105BT_2964 PL8BT_2969 GH2BT_2970 GH29BT_3009 GH3BT_3014 CBM32BT_3015 CBM32BT_3026 GH30BT_3043 GH30

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BT_3050 GH18BT_3065 GH27BT_3082 GH32BT_3085 GH31BT_3086 GH31BT_3087 GH66BT_3092 GH2BT_3094 GH43BT_3096 GH51BT_3108 GH43BT_3114 GH2BT_3130 GH92BT_3131 GH36BT_3133 GH36BT_3155 GH95BT_3160 GH110BT_3163 GH97BT_3169 GH31-CBM32BT_3173 GH95BT_3176 GH16BT_3178 GH20BT_3179 GH2BT_3246 CE4BT_3292 GH2BT_3293 GH2-CBM32BT_3294 GH97BT_3299 GH31BT_3300 GH3BT_3301 GH76BT_3312 GH30BT_3314 GH3BT_3324 PL8BT_3340 GH2BT_3348 GH88BT_3350 PL8BT_3362 GT9BT_3365 GT2BT_3366 GT2BT_3367 GT4BT_3368 GT4BT_3369 GT4

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BT_3370 GT2BT_3371 GT2BT_3372 GT2BT_3377 GT14BT_3379 GT2BT_3387 CE4BT_3388 GT2BT_3448 GT28BT_3467 GH43BT_3501 GH76BT_3513 GH2BT_3514 GH115BT_3515 GH43BT_3516 GH43-GH43BT_3521 GH76BT_3524 GH76BT_3527 GH92BT_3528 GH125BT_3530 GH92BT_3542 CBM62BT_3567 GH3BT_3588 CE9BT_3590 GH89BT_3592 CBM51-GH27BT_3598 GH20BT_3599 GH2BT_3622 GT2BT_3654 GH35-CBM32BT_3655 GH43BT_3656 GH43-GH43BT_3657 GH51BT_3659 GH31BT_3661 GH97BT_3662 GH43-CBM32BT_3663 GH43BT_3664 GH97BT_3665 GH29BT_3675 GH43BT_3683 GH16-GH43BT_3685 GH43BT_3687 GH105

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BT_3694 GT2BT_3698 GH13a-CBM58-GH13bBT_3703 GH97BT_3704 GH13BT_3753 GH18BT_3773 GH92BT_3774 GH38-CBM32BT_3775 GT32BT_3776 GT32BT_3781 GH125BT_3782 GH76BT_3784 GH92BT_3792 GH76BT_3797 GH36BT_3798 GH29BT_3858 GH92BT_3862 GH99BT_3868 GH20BT_3956 GH29BT_3962 GH92BT_3963 GH92BT_3965 GH92BT_3987 GH18BT_3990 GH92BT_3991 GH92BT_3994 GH92BT_3999 GH23BT_4004 GT19BT_4040 CBM32BT_4050 GH2BT_4072 GH38BT_4073 GH92BT_4074 GH2BT_4076 GH78BT_4077 CE1BT_4092 GH92BT_4093 GH92BT_4095 GH43BT_4108 GH105BT_4109 CE8BT_4110 CE12-CE8

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BT_4115 PL1BT_4116 PL1BT_4119 PL1BT_4123 GH28BT_4132 CBM32BT_4136 GH29-CBM32BT_4145 GH106BT_4146 GH28BT_4149 GH28BT_4150 CE12BT_4151 GH2BT_4152 GH43-GH42BT_4153 GH28BT_4154 CE4BT_4155 GH28BT_4156 GH2BT_4157 GH27BT_4160 GH35BT_4170 PL9BT_4173 CE12-CE12BT_4174 GH105BT_4175 PL11BT_4176 GH105BT_4179 CE4BT_4180 CE6BT_4181 GH2BT_4183 PL9BT_4185 GH43BT_4187 GH28BT_4206 CE11BT_4241 GH2BT_4243 GH109BT_4244 CBM32BT_4251 GH110BT_4252 GH109BT_4272 CBM32BT_4280 GT4BT_4281 GT2BT_4282 GT4BT_4304 GT4BT_4305 GH57

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BT_4307 GT5BT_4337 GH20BT_4359 GH89BT_4394 GH20BT_4395 GH84BT_4406 GH18BT_4487 GH23BT_4564 GT2BT_4581 GH97BT_4632 CBM32BT_4652 PL15BT_4657 PL12BT_4658 GH88BT_4662 PL12BT_4667 GH2BT_4668 GH53BT_4675 PL13BT_4681 GH20BT_4682 GH95BT_4684 GH2BT_4689 CBM48-GH13BT_4690 GH13BT_4709 GH18BT_4713 GH29BT_4714 GH3

ORF Name CAZy module(s)BACUNI_00066 GH116-CBM38BACUNI_00150 GH30BACUNI_00160 GH125BACUNI_00168 GH76BACUNI_00170 GH38-CBM32BACUNI_00186 CBM32-GH2-CBM32BACUNI_00190 GH97BACUNI_00191 GH38-CBM32BACUNI_00193 GH76BACUNI_00195 GH125BACUNI_00199 GH76BACUNI_00200 GH92BACUNI_00201 GH78

Bacteroides uniformis (ATCC 8492)

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BACUNI_00202 GH3BACUNI_00204 GH31BACUNI_00255 GT2BACUNI_00268 GH3BACUNI_00269 CE1BACUNI_00319 GH43BACUNI_00321 GH5BACUNI_00323 GH31BACUNI_00324 GH2BACUNI_00325 GH3BACUNI_00326 GH95BACUNI_00356 GH26BACUNI_00373 GH26BACUNI_00378 GH5BACUNI_00379 GH5BACUNI_00380 CE7BACUNI_00383 GH2BACUNI_00385 GH94BACUNI_00387 GH97BACUNI_00392 GH3BACUNI_00393 GH3BACUNI_00462 GT2BACUNI_00464 GH97BACUNI_00666 GT20BACUNI_00667 GH15BACUNI_00717 GH13BACUNI_00721 CBM48-GH13BACUNI_00754 GH20BACUNI_00837 GT30BACUNI_00888 GT35BACUNI_00919 GH3BACUNI_00920 CE1BACUNI_00921 CE1BACUNI_00922 CE1BACUNI_00923 GH3BACUNI_00962 GT11BACUNI_00963 GT2BACUNI_00964 GT4BACUNI_00966 GT4BACUNI_00967 GT2BACUNI_00969 GT2

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BACUNI_00978 GT9BACUNI_00980 GT2BACUNI_00984 GT4BACUNI_01004 GH88BACUNI_01024 GH2BACUNI_01029 PL8BACUNI_01042 GH3BACUNI_01044 GH5BACUNI_01082 GH78BACUNI_01083 GH43BACUNI_01084 GH43BACUNI_01085 GH43BACUNI_01086 GH43BACUNI_01090 GH2BACUNI_01106 GH43BACUNI_01126 GH29BACUNI_01140 GH9-CE4BACUNI_01155 GH32BACUNI_01156 GH32BACUNI_01158 CBM38-GH32BACUNI_01159 GH32BACUNI_01184 GH20BACUNI_01201 GH65BACUNI_01204 GH53BACUNI_01205 GH2BACUNI_01213 GH13BACUNI_01214 GH13BACUNI_01238 CBM48-GH13BACUNI_01282 GH23BACUNI_01322 CE1BACUNI_01364 GH51BACUNI_01390 GH25BACUNI_01414 GT2BACUNI_01464 GH13BACUNI_01476 GH97BACUNI_01484 GH3BACUNI_01486 GH16BACUNI_01494 GT2BACUNI_01554 GH31BACUNI_01567 GH20BACUNI_01573 GH84

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BACUNI_01594 GH97BACUNI_01595 GH13BACUNI_01608 GH18BACUNI_01720 GT83BACUNI_01724 GT2BACUNI_01742 CBM20-CBM20-GH77BACUNI_01811 GT3BACUNI_01812 GT35BACUNI_01831 GT2BACUNI_01833 GT2BACUNI_01834 GT2BACUNI_01835 GT4BACUNI_01837 GT2BACUNI_01838 GT2BACUNI_01855 GT4BACUNI_01856 GT4BACUNI_01857 GT2BACUNI_01902 GT2BACUNI_01903 GT4BACUNI_01905 GT2BACUNI_01908 GT2BACUNI_01946 GH66BACUNI_01947 GH31BACUNI_01948 GH97BACUNI_02104 GT26BACUNI_02106 GT4BACUNI_02106 GT4BACUNI_02107 GT4BACUNI_02108 GT4BACUNI_02109 GT2BACUNI_02110 GT32BACUNI_02113 GT2BACUNI_02174 GT51BACUNI_02183 GH36BACUNI_02256 GT4BACUNI_02258 GT2BACUNI_02299 GT2BACUNI_02560 GT26BACUNI_02635 GH92BACUNI_02639 GH92BACUNI_02640 GH18

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BACUNI_02645 GH92BACUNI_02648 GH92BACUNI_02708 GH108BACUNI_02735 GT51BACUNI_02787 GT4BACUNI_02793 GT4BACUNI_02794 GT4BACUNI_02798 GT2BACUNI_02826 GH33BACUNI_02946 GH2BACUNI_02952 GT2BACUNI_02953 GT4BACUNI_03063 GH76BACUNI_03064 GH125BACUNI_03065 GH2BACUNI_03067 GH92BACUNI_03075 GH3BACUNI_03076 GH109BACUNI_03081 GH109BACUNI_03086 GH74BACUNI_03090 GH76BACUNI_03096 GH92BACUNI_03098 GH43BACUNI_03099 GH125BACUNI_03124 GH109BACUNI_03134 GH105BACUNI_03139 GH3BACUNI_03141 GH2BACUNI_03142 GH2BACUNI_03143 GH97BACUNI_03144 CE7BACUNI_03279 GH92BACUNI_03282 GH63BACUNI_03283 GH125BACUNI_03284 GH20BACUNI_03326 GH105BACUNI_03327 GH43-GH43BACUNI_03328 GH97BACUNI_03329 GH51BACUNI_03331 GH51BACUNI_03332 GH2

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BACUNI_03347 GH43BACUNI_03350 GH43-GH35-CBM32BACUNI_03370 GT2BACUNI_03398 GT5BACUNI_03400 GH57BACUNI_03401 GT4BACUNI_03432 GH20BACUNI_03433 GH3BACUNI_03477 CE11BACUNI_03534 GH3BACUNI_03661 GT19BACUNI_03669 GH23-CBM50BACUNI_03701 GH92BACUNI_03703 GH125BACUNI_03750 GH2BACUNI_03751 GH30BACUNI_03795 GH43BACUNI_03796 GH2BACUNI_03803 GH5BACUNI_03804 GH97BACUNI_03805 GH2BACUNI_03806 GH42BACUNI_03807 GH2BACUNI_03808 GH29BACUNI_03809 GH31BACUNI_03821 GH43-CBM32BACUNI_03824 GH3BACUNI_03829 GH3BACUNI_03841 GH9BACUNI_03859 GH125BACUNI_03870 GT28BACUNI_03890 CBM32-GH2BACUNI_03891 GH26BACUNI_03909 GH63BACUNI_03910 GH2BACUNI_03913 GH2BACUNI_03915 GH63BACUNI_03954 CE1BACUNI_03957 GH43-CBM32BACUNI_03959 GH43-CBM32BACUNI_03961 GH3

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BACUNI_03971 GH2-CBM57BACUNI_03973 GH3BACUNI_04017 GH3BACUNI_04018 GH3BACUNI_04019 GH5BACUNI_04020 GH3BACUNI_04021 GH78BACUNI_04062 CBM32-CBM32-CBM32BACUNI_04064 GH92BACUNI_04088 GT14BACUNI_04093 GT4BACUNI_04094 GT2BACUNI_04176 GH9BACUNI_04180 GH31BACUNI_04182 GH9BACUNI_04186 GH9BACUNI_04194 CE4BACUNI_04244 GT2BACUNI_04261 GH73-CBM50-CBM50BACUNI_04299 GT4BACUNI_04300 GT4BACUNI_04308 GT4BACUNI_04347 GT4BACUNI_04351 GT4BACUNI_04352 GT4BACUNI_04354 CE4BACUNI_04356 GT2BACUNI_04447 GH18BACUNI_04498 GH115BACUNI_04499 GH2BACUNI_04500 GH30BACUNI_04501 GH28-GH43BACUNI_04508 GH28BACUNI_04509 GH2BACUNI_04510 CBM35BACUNI_04512 CE12-CE4BACUNI_04528 GH3BACUNI_04530 GH3BACUNI_04535 GH2BACUNI_04625 GH23BACUNI_04671 GH3

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BACUNI_04697 GH55BACUNI_04698 GH55BACUNI_04707 GH9

ORF Name CAZy module(s)BVU_0007 GT2BVU_0029 GH67BVU_0030 GH115BVU_0031 GH43BVU_0032 GH43-CBM6-CE1BVU_0039 GH43BVU_0040 GH43BVU_0041 GH10BVU_0044 GH16BVU_0057 CE9BVU_0085 GH20BVU_0098 CE11BVU_0102 GH29BVU_0104 GH110BVU_0105 GH109BVU_0115 GH88BVU_0116 GH43BVU_0117 GH97BVU_0121 GH28BVU_0124 GH28BVU_0131 GH3BVU_0132 GH92BVU_0133 GH97BVU_0137 GH88BVU_0145 GH3BVU_0151 GH105BVU_0152 PL11BVU_0153 GH28BVU_0154 GH115BVU_0160 CE12-CE12BVU_0161 PL11BVU_0162 GH2BVU_0163 GH106BVU_0174 GH78BVU_0175 CE15

Bacteroides vulgatus (ATCC 8482)

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BVU_0176 PL11BVU_0177 GH28BVU_0178 GH105BVU_0179 GH42BVU_0180 GH43-GH43-CBM32BVU_0181 GH2BVU_0182 CE12BVU_0183 GH28BVU_0186 GH28BVU_0187 GH106BVU_0212 GH31BVU_0213 GH97BVU_0217 GH29BVU_0301 GH2BVU_0302 GH63BVU_0340 GH109BVU_0391 GH2BVU_0393 GH2BVU_0491 GH31BVU_0495 GH35-CBM32BVU_0496 GH51BVU_0497 GH43-GH43BVU_0498 GH30BVU_0507 GH43BVU_0508 GH43BVU_0509 GH43-GH43BVU_0514 GH105BVU_0528 GT2BVU_0535 GH29-CBM32BVU_0536 GH2BVU_0537 GH20BVU_0555 GH92BVU_0556 GH3BVU_0587 GH30BVU_0605 GH23BVU_0607 GH2BVU_0611 GH109BVU_0617 GH18BVU_0620 GH97BVU_0624 GH92BVU_0625 GH92

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BVU_0628 GH92BVU_0640 GH27BVU_0687 GT26BVU_0736 GH36BVU_0741 GH3BVU_0742 GH2-CBM32BVU_0746 GH36BVU_0752 GH92BVU_0753 GH95BVU_0754 GH92BVU_0755 GH92BVU_0843 GH30BVU_0844 GH30BVU_0891 GT4BVU_0892 GT2BVU_0948 CBM32BVU_0949 CBM32BVU_0950 GH109BVU_0997 GH2BVU_1001 GH51BVU_1002 GH43BVU_1004 GH97BVU_1008 GH43BVU_1023 CE4BVU_1029 GT2BVU_1046 GH29BVU_1047 GH36BVU_1061 GT9BVU_1066 GT2BVU_1067 GT2BVU_1068 GT14BVU_1069 GT4BVU_1071 GT2BVU_1073 GT4BVU_1074 GT2BVU_1076 GT2BVU_1078 GT83BVU_1104 CE4BVU_1116 PL10BVU_1123 GH43-CBM32BVU_1124 GH97

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BVU_1151 GH2BVU_1162 GH3BVU_1196 GH20BVU_1246 GH29-CBM32BVU_1268 GH95BVU_1273 GH18BVU_1304 GH105BVU_1343 CE7BVU_1364 GH63BVU_1365 GH2BVU_1381 GH97BVU_1382 GH13BVU_1387 CBM20-CBM20-GH77BVU_1397 GT28BVU_1476 GT30BVU_1547 GT26BVU_1663 GH32BVU_1725 GT2BVU_1727 GT4BVU_1728 GT4BVU_1729 GT14BVU_1730 GT2BVU_1745 GH29BVU_1747 GH28BVU_1749 GH88BVU_1767 GH28BVU_1768 GH2BVU_1769 GH28BVU_1783 GH105BVU_1785 GH2BVU_1787 GH78BVU_1790 GH43BVU_1797 GH105BVU_1798 CE8BVU_1801 GH33BVU_1803 CE8BVU_1808 GH2BVU_1809 GH2BVU_1810 GH31BVU_1813 PL10BVU_1815 CE12-CE8

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BVU_1860 GH89BVU_1872 GH105BVU_1912 GH23-CBM50BVU_1917 GT19BVU_1983 GH43BVU_1985 GH28BVU_2041 GH109BVU_2069 GH84BVU_2160 CE12-CE4BVU_2161 CBM35BVU_2162 GH2BVU_2163 GH28BVU_2168 GH28BVU_2169 GH43BVU_2170 GH30BVU_2171 GH2BVU_2172 GH115BVU_2198 GH123BVU_2209 GH20BVU_2224 GH2BVU_2229 GH43BVU_2230 GH43BVU_2231 GH43BVU_2259 GT2BVU_2283 GH110BVU_2287 GH25BVU_2342 GH73BVU_2357 GH23BVU_2395 GT2BVU_2396 GT4BVU_2399 GT4BVU_2400 GT4BVU_2433 GH29BVU_2485 CE1BVU_2597 GT2BVU_2634 GT2BVU_2642 GH95BVU_2643 GH105BVU_2645 GH78-GH33BVU_2648 GH78BVU_2653 GT2

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BVU_2654 GT2BVU_2657 GT4BVU_2662 GT4BVU_2665 GT4BVU_2688 GH2-CBM57BVU_2694 GH2BVU_2695 GH2BVU_2696 GH106BVU_2731 GH78BVU_2732 GH28BVU_2775 GT4BVU_2776 GH57BVU_2897 GT5BVU_2910 GH2BVU_2915 PL1BVU_2917 PL1BVU_2931 GH31BVU_2950 GT2BVU_2954 GT2BVU_2979 GH95BVU_3034 CBM48-GH13BVU_3210 GT11BVU_3245 GH20BVU_3258 GH15BVU_3259 GT20BVU_3322 CBM48-GH13BVU_3336 GT51BVU_3344 GT51BVU_3442 GT26BVU_3443 GT4BVU_3446 GT2BVU_3448 GT11BVU_3450 GT2BVU_3510 GT35BVU_3559 GT35BVU_3560 GT3BVU_3844 GH2BVU_3860 GT2BVU_3924 GT26BVU_3925 GT4BVU_3927 GT4

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BVU_3928 GT2BVU_3930 GT4BVU_3961 GT2BVU_3963 GT2BVU_3966 GT2BVU_3967 GT2BVU_3971 GT4BVU_3973 GT2BVU_3974 GT2BVU_3975 GT4BVU_3976 GT4BVU_3978 GT4BVU_3980 GT2BVU_3981 GT4BVU_3982 GT2BVU_3991 GH13BVU_4019 GT4BVU_4020 GT4BVU_4026 GT2BVU_4051 CBM9BVU_4052 GH29BVU_4054 GH51BVU_4133 CE9BVU_4134 GH2BVU_4135 GH92BVU_4136 GH20BVU_4138 GH20-CBM32BVU_4139 GH2BVU_4142 GH20BVU_4143 GH33

Bacteroides WH2ORF Name CAZy module(s)BACWH2_0006 GH36BACWH2_0024 GH18BACWH2_0027 CE9BACWH2_0029 GH20BACWH2_0030 GH20-CBM32BACWH2_0097 GT30BACWH2_0121 GH95BACWH2_0145 GH3

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BACWH2_0146 GH2BACWH2_0147 GH31BACWH2_0149 GH5BACWH2_0150 GH5BACWH2_0175 GH92BACWH2_0176 GH92BACWH2_0177 CBM13-GH2BACWH2_0178 GH3BACWH2_0179 GH39BACWH2_0180 GH16BACWH2_0182 GH78BACWH2_0232 GH3BACWH2_0235 GH29BACWH2_0250 CE1BACWH2_0251 GH43-CBM32BACWH2_0259 GH3BACWH2_0312 GH31BACWH2_0313 GH97BACWH2_0314 GH95BACWH2_0316 CE7BACWH2_0328 GH30BACWH2_0329 GH2BACWH2_0331 GH105BACWH2_0332 PL17BACWH2_0333 GH2BACWH2_0339 PL8-GH78BACWH2_0339 PL8-GH78BACWH2_0340 GH28BACWH2_0341 GH88BACWH2_0342 GH2BACWH2_0343 GH2BACWH2_0344 PL8BACWH2_0345 GH79BACWH2_0346 CBM32-PL8BACWH2_0350 GH106BACWH2_0364 GH92BACWH2_0369 GH28BACWH2_0370 GH92BACWH2_0373 GH89BACWH2_0399 GT2BACWH2_0401 GT2

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BACWH2_0406 GT4BACWH2_0407 GT4BACWH2_0408 GT2BACWH2_0418 GH92BACWH2_0419 GH92BACWH2_0420 GH28BACWH2_0452 GH3BACWH2_0453 GH2BACWH2_0454 GH26BACWH2_0469 GH3BACWH2_0470 GH8BACWH2_0472 GH29BACWH2_0475 GH29BACWH2_0492 GH3BACWH2_0493 GH50BACWH2_0496 GH3BACWH2_0497 GH3BACWH2_0516 GH78BACWH2_0522 GH51BACWH2_0523 GH30BACWH2_0524 CBM32BACWH2_0527 GH2BACWH2_0528 CBM13BACWH2_0530 GH42BACWH2_0562 CE4BACWH2_0588 CE1BACWH2_0590 GH43-CBM13BACWH2_0593 GH9BACWH2_0594 GH43BACWH2_0595 GH3BACWH2_0596 GH43-CBM6BACWH2_0627 GH89BACWH2_0652 GH27-GH43-CBM6BACWH2_0653 GH43BACWH2_0654 CBM51-GH27BACWH2_0655 GH31BACWH2_0656 GH43-CBM6BACWH2_0657 GH97BACWH2_0658 GH43BACWH2_0659 GH31BACWH2_0660 GH2

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BACWH2_0661 GH97BACWH2_0664 GH43BACWH2_0665 GH51BACWH2_0666 GH43BACWH2_0677 GH5-GH43BACWH2_0708 GH95BACWH2_0709 GH105BACWH2_0750 GH3BACWH2_0751 GH43BACWH2_0757 GH78BACWH2_0759 GH2-CBM57BACWH2_0760 GH2BACWH2_0761 GH2BACWH2_0784 CE1BACWH2_0791 GT2BACWH2_0793 GT2BACWH2_0795 GT2BACWH2_0799 GT4BACWH2_0976 GH73-CBM50-CBM50BACWH2_1007 GT2BACWH2_1023 GT3BACWH2_1024 GT35BACWH2_1046 GT2BACWH2_1047 GT32BACWH2_1060 GT2BACWH2_1061 GT2BACWH2_1063 GT4BACWH2_1064 GT2BACWH2_1129 GH43BACWH2_1147 GH66BACWH2_1148 GH31BACWH2_1149 GH97BACWH2_1158 GH65BACWH2_1263 GT4BACWH2_1264 GT4BACWH2_1265 GT4BACWH2_1266 GT2BACWH2_1267 GT2BACWH2_1368 GH13BACWH2_1372 CBM48-GH13BACWH2_1432 GH43

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BACWH2_1466 GH28BACWH2_1468 GH3BACWH2_1474 GH2BACWH2_1475 GH2-GH43BACWH2_1476 GH35BACWH2_1479 GH51BACWH2_1498 CE12-CE12BACWH2_1502 GH2BACWH2_1504 GH2BACWH2_1510 GH3BACWH2_1511 GH2BACWH2_1516 GH92BACWH2_1517 GH3BACWH2_1522 GH110BACWH2_1524 GH110BACWH2_1527 GH110BACWH2_1548 GH105BACWH2_1549 GH20BACWH2_1718 PL10BACWH2_1794 GT2BACWH2_1798 CE4BACWH2_1814 GH23-CBM50BACWH2_1826 GT19BACWH2_1854 GT2BACWH2_1893 CE4BACWH2_1895 GT2BACWH2_1925 GT2BACWH2_1950 GH36BACWH2_1985 GT2BACWH2_1988 GT32BACWH2_1989 GT2BACWH2_1995 GH2BACWH2_2129 GH24BACWH2_2194 GT4BACWH2_2195 GT4BACWH2_2196 GT2BACWH2_2197 GT2BACWH2_2198 GT4BACWH2_2200 GT2BACWH2_2201 GT4BACWH2_2305 GH95

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BACWH2_2306 PL8BACWH2_2307 GH105BACWH2_2309 GH2BACWH2_2310 GH88BACWH2_2312 GH105BACWH2_2329 GH36BACWH2_2330 GH31BACWH2_2331 GH97BACWH2_2332 GH97BACWH2_2333 GH28BACWH2_2336 GH28BACWH2_2337 PL6BACWH2_2389 CBM48-GH13BACWH2_2409 CBM48-GH13BACWH2_2415 GH2BACWH2_2416 GH53BACWH2_2427 GH65BACWH2_2457 GH36BACWH2_2464 GH32BACWH2_2468 GH32BACWH2_2482 GH9-CE4BACWH2_2535 GH9BACWH2_2556 GT2BACWH2_2558 GT2BACWH2_2563 GT4BACWH2_2565 GT4BACWH2_2566 GT4BACWH2_2567 GH18BACWH2_2582 GH43-CBM6BACWH2_2588 GH28BACWH2_2590 GH28BACWH2_2592 GH63BACWH2_2596 CBM48-GH13BACWH2_2609 GH13BACWH2_2612 GH13BACWH2_2614 GH16BACWH2_2615 GH29-CBM32BACWH2_2616 GH2BACWH2_2617 GH20BACWH2_2626 GH50BACWH2_2636 GH2

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BACWH2_2650 GT28BACWH2_2675 GH2BACWH2_2677 GH63BACWH2_2696 GH3BACWH2_2697 CE1BACWH2_2708 GH97BACWH2_2709 GH13BACWH2_2710 GH13BACWH2_2734 GT4BACWH2_2735 GT2BACWH2_2736 GT4BACWH2_2737 GT4BACWH2_2738 GT2BACWH2_2740 GT2BACWH2_2741 GT2BACWH2_2742 GT2BACWH2_2747 GT9BACWH2_2783 GH88BACWH2_2799 PL8BACWH2_2804 GH117BACWH2_2807 PL8BACWH2_2817 GH30BACWH2_2821 GH2BACWH2_2822 GH88BACWH2_2840 GH3BACWH2_2841 GH5BACWH2_2842 GH30BACWH2_2862 GH51BACWH2_2893 GT2BACWH2_3094 GH88BACWH2_3095 GH43BACWH2_3096 GH97BACWH2_3102 GH88BACWH2_3107 GH2BACWH2_3108 GH28BACWH2_3109 GH97BACWH2_3111 GH28BACWH2_3114 GH28BACWH2_3115 GH2BACWH2_3116 GH51BACWH2_3117 GH43-GH43-GH43

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BACWH2_3126 GH28BACWH2_3130 CBM32BACWH2_3165 GH106BACWH2_3186 GH2BACWH2_3190 CE1BACWH2_3207 PL1BACWH2_3220 GH23BACWH2_3230 PL1BACWH2_3231 GH105BACWH2_3245 CE6BACWH2_3326 GT2BACWH2_3346 GT51BACWH2_3352 GH25BACWH2_3376 GT2BACWH2_3379 GT4BACWH2_3381 GT2BACWH2_3396 GH30BACWH2_3397 GH10-GH10BACWH2_3403 GH115BACWH2_3417 GH28BACWH2_3420 GH51BACWH2_3429 GH43BACWH2_3434 GH43BACWH2_3435 GH51BACWH2_3436 GH43BACWH2_3446 PL8BACWH2_3447 GH105BACWH2_3453 GH88BACWH2_3454 GH2BACWH2_3455 GH2BACWH2_3456 GH109BACWH2_3483 GH109BACWH2_3543 CE11BACWH2_3565 GH3BACWH2_3569 CE8BACWH2_3570 PL1BACWH2_3598 GH28BACWH2_3599 GH78-GH33BACWH2_3601 GH43BACWH2_3603 GH95BACWH2_3614 CE7

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BACWH2_3615 CE12-CE8BACWH2_3617 CE8BACWH2_3618 GH105BACWH2_3694 GH108BACWH2_3702 GT2BACWH2_3704 GT2BACWH2_3705 GT4BACWH2_3707 GT4BACWH2_3748 CBM32BACWH2_3761 GH105BACWH2_3764 GH42BACWH2_3765 GH3BACWH2_3766 GH105BACWH2_3787 GT83BACWH2_3789 GT2BACWH2_3797 CBM20-CBM20-GH77BACWH2_3803 GT2BACWH2_3820 GH43-GH35-CBM32-CBM32BACWH2_3821 GH115BACWH2_3822 CE12BACWH2_3825 GH43BACWH2_3826 GH28BACWH2_3836 GH43BACWH2_3837 GH2BACWH2_3838 GH51BACWH2_3839 GH51BACWH2_3840 GH97-GH43BACWH2_3841 GH43-GH43BACWH2_3842 GH105BACWH2_3845 GH43BACWH2_3849 GH43-GH16BACWH2_3850 GH16BACWH2_3851 CBM32BACWH2_3889 PL13BACWH2_3896 GH88BACWH2_3897 PL12BACWH2_3903 PL15BACWH2_3933 GH2BACWH2_3983 GT4BACWH2_3985 GT4BACWH2_4008 GH20

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BACWH2_4021 GH2BACWH2_4030 GH10-CE1BACWH2_4055 GH28BACWH2_4077 GH78BACWH2_4094 GH92BACWH2_4099 GH116BACWH2_4146 GH13BACWH2_4199 GT4BACWH2_4204 GT4BACWH2_4210 GH97BACWH2_4213 GH3BACWH2_4215 GH16BACWH2_4223 GH20-CBM32BACWH2_4236 GH2BACWH2_4243 GT51BACWH2_4249 GH10a-CBM22-CBM22-GH10bBACWH2_4251 GH35BACWH2_4254 GH10-GH43BACWH2_4255 GH43BACWH2_4257 GH67BACWH2_4260 GH26BACWH2_4262 GH43BACWH2_4263 GH26BACWH2_4267 GH8BACWH2_4268 CE6-GH95BACWH2_4269 CE1BACWH2_4270 GH5BACWH2_4271 GH10BACWH2_4272 GH10-GH10BACWH2_4281 GH115BACWH2_4282 GH31BACWH2_4293 GH92BACWH2_4296 GH92BACWH2_4309 GH92BACWH2_4310 GH97BACWH2_4311 GH18BACWH2_4316 GH92BACWH2_4319 GH92BACWH2_4327 GT5BACWH2_4329 GH57BACWH2_4330 GT4

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BACWH2_4340 CE12BACWH2_4342 GH3BACWH2_4344 GH95BACWH2_4345 GH28BACWH2_4360 CE15BACWH2_4364 GH3BACWH2_4370 GH29BACWH2_4371 GH78BACWH2_4372 GH78BACWH2_4373 GH29BACWH2_4374 GH31BACWH2_4379 GH28BACWH2_4380 GH106BACWH2_4382 GH95BACWH2_4383 GH29BACWH2_4386 GH3BACWH2_4416 GT2BACWH2_4471 GT2BACWH2_4485 GH95BACWH2_4499 GH43BACWH2_4500 GH92BACWH2_4501 GH3BACWH2_4502 GH43BACWH2_4503 GH30BACWH2_4538 GH95BACWH2_4545 GH30BACWH2_4546 GH2BACWH2_4547 GH30BACWH2_4552 GH30BACWH2_4560 GH38BACWH2_4561 GH38-CBM32BACWH2_4570 GH67BACWH2_4571 GH97BACWH2_4572 GH105BACWH2_4573 GH125BACWH2_4574 GH76BACWH2_4576 GH2BACWH2_4615 GH2BACWH2_4625 GH43BACWH2_4628 GH105BACWH2_4629 GH2

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BACWH2_4632 GH105BACWH2_4633 GH115BACWH2_4634 GH31BACWH2_4635 GH63BACWH2_4638 GH43BACWH2_4639 GH43BACWH2_4754 GT2BACWH2_4762 GT2BACWH2_4783 GT51BACWH2_4845 GH28BACWH2_4872 GH23BACWH2_4930 GH27BACWH2_4933 GH97BACWH2_4940 PL10-CE8BACWH2_4943 CE8BACWH2_4944 GH2BACWH2_4946 GH3BACWH2_4958 GT4BACWH2_4982 GH43BACWH2_4985 GH3BACWH2_4986 GH28BACWH2_4987 GH28BACWH2_4988 GH106BACWH2_4989 GH106BACWH2_5074 GH26BACWH2_5075 GH26BACWH2_5080 GH5BACWH2_5081 GH5BACWH2_5082 CE7BACWH2_5084 GH3BACWH2_5089 GH3BACWH2_5090 GH3BACWH2_5095 GH43-GH10BACWH2_5096 GH43BACWH2_5098 GT2BACWH2_5116 GH2BACWH2_5125 PL1BACWH2_5130 GH28BACWH2_5132 GH105BACWH2_5137 GH28BACWH2_5138 PL11

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BACWH2_5139 GH106BACWH2_5140 GH105BACWH2_5145 GH43-CBM32BACWH2_5146 GH43-CBM6BACWH2_5147 GH43-CBM6BACWH2_5148 GH43BACWH2_5165 GH29BACWH2_5166 GH105BACWH2_5167 GH2BACWH2_5168 GH109BACWH2_5172 GH20BACWH2_5204 GT51BACWH2_5252 CE2BACWH2_5257 GH2BACWH2_5261 CBM51-GH27BACWH2_5293 GT4BACWH2_5294 GT26BACWH2_5303 GH3BACWH2_5304 GH3BACWH2_5379 GH97BACWH2_5380 GH43-CBM32BACWH2_5397 GH105BACWH2_5398 GH42BACWH2_5405 GH2BACWH2_5406 PL11BACWH2_5407 GH105BACWH2_5410 CBM6BACWH2_5411 GH31BACWH2_5412 GH28BACWH2_5418 GH95BACWH2_5419 GH3BACWH2_5532 GH2BACWH2_5534 PL1BACWH2_5544 PL1BACWH2_5546 GH43BACWH2_5549 GH78BACWH2_5569 GH78BACWH2_5570 GH28BACWH2_5572 GH78-GH33BACWH2_5574 GH105BACWH2_5575 GH95

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BACWH2_5613 GH29

ORF Name CAZy module(s)BALAC2494_00004 GT2BALAC2494_00010 CBM48-GH13BALAC2494_00144 GT4BALAC2494_00225 GH3BALAC2494_00245 GT4BALAC2494_00298 GT4BALAC2494_00433 CBM48-GH13BALAC2494_00519 GT4BALAC2494_00605 GH43BALAC2494_00608 GH43BALAC2494_00612 GH43BALAC2494_00631 GT2BALAC2494_00633 GT2BALAC2494_00637 GH42BALAC2494_00644 GH2BALAC2494_00702 GH13BALAC2494_00756 CBM48-GH13BALAC2494_00759 GH77BALAC2494_00857 GH2BALAC2494_00904 GT51BALAC2494_00949 CE4BALAC2494_00996 CE4BALAC2494_01045 GT35BALAC2494_01056 GH51BALAC2494_01067 GH42BALAC2494_01068 GH30BALAC2494_01073 GH3BALAC2494_01144 GH36BALAC2494_01149 GH36BALAC2494_01151 GH13BALAC2494_01173 GH77BALAC2494_01174 GH13BALAC2494_01178 CBM48-GH13BALAC2494_01188 GH3BALAC2494_01193 GT39BALAC2494_01206 GH13BALAC2494_01207 GH13

Bifidobacterium animalis subsp. lactis (CNCM I-2494)

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BALAC2494_01213 GH36BALAC2494_01223 GT2BALAC2494_01231 GH25BALAC2494_01232 GH25BALAC2494_01233 GT2BALAC2494_01236 GT2BALAC2494_01237 GT2BALAC2494_01282 GH13BALAC2494_01288 GH5-CBM10BALAC2494_01318 GH94BALAC2494_01320 GH30BALAC2494_01333 GT2BALAC2494_01334 GT2BALAC2494_01335 GT1BALAC2494_01345 GT2BALAC2494_01347 GT2BALAC2494_01349 GT2BALAC2494_01351 GT2BALAC2494_01352 GT2BALAC2494_01354 GT2BALAC2494_01359 GT2BALAC2494_01376 GT51BALAC2494_01473 GH32BALAC2494_01677 GH1BALAC2494_01751 GH13BALAC2494_01775 GT32BALAC2494_01853 CE2BALAC2494_01923 GH13BALAC2494_01971 CBM23BALAC2494_02032 GH13BALAC2494_02078 GH13

ORF Name CAZy module(s)CLOSCI_00021 GH25CLOSCI_00147 CE4CLOSCI_00156 GT2CLOSCI_00161 GT2CLOSCI_00168 GT4CLOSCI_00343 GT2CLOSCI_00371 CE4

Clostridium scindens (ATCC 35704)

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CLOSCI_00373 GT28CLOSCI_00436 GT5CLOSCI_00531 GH73CLOSCI_00704 CE4CLOSCI_00722 CBM50-GH18CLOSCI_00729 GT35CLOSCI_00758 CBM48-GH13CLOSCI_01053 GH73CLOSCI_01158 GT4CLOSCI_01175 CE4CLOSCI_01197 CBM48-GH13CLOSCI_01203 GH13CLOSCI_01221 GT4CLOSCI_01435 CE9CLOSCI_01445 GH13CLOSCI_01470 GH23CLOSCI_01574 GH77CLOSCI_01666 CBM32CLOSCI_01670 GH65CLOSCI_01957 GH25CLOSCI_01996 GH13CLOSCI_02086 GH29CLOSCI_02092 GH65CLOSCI_02371 GH42CLOSCI_02373 GH2CLOSCI_02428 GT2CLOSCI_02433 GT2CLOSCI_02437 GT2CLOSCI_02438 GT4-GT4CLOSCI_02439 GT2CLOSCI_02440 GT2CLOSCI_02442 GT2CLOSCI_02581 GH23CLOSCI_02633 GT35CLOSCI_02650 GH18CLOSCI_02671 GT28CLOSCI_02693 CBM48-GH13CLOSCI_02836 GT2CLOSCI_03128 GH77CLOSCI_03192 GH112CLOSCI_03332 GH68

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CLOSCI_03334 GH68CLOSCI_03446 GT2CLOSCI_03673 GT51CLOSCI_03871 CE4CLOSCI_04014 GT2

ORF Name CAZy module(s)CLOSPI_00076 CBM48-GH13CLOSPI_00079 PL8-CBM32-CBM32CLOSPI_00080 GT35CLOSPI_00081 CBM48-GH13CLOSPI_00161 GH25CLOSPI_00173 CE9CLOSPI_00293 CBM32-CBM32-GH36-CBM32CLOSPI_00329 CBM32-GH92-CBM6CLOSPI_00338 GH92-CBM32CLOSPI_00340 GH92-CBM32-CBM32CLOSPI_00343 GH92-CBM6-CBM6-CBM6CLOSPI_00354 GH32CLOSPI_00499 GH123CLOSPI_00500 GH84-CBM32-CBM32CLOSPI_00503 CE1CLOSPI_00504 GH29CLOSPI_00505 GH29CLOSPI_00506 GH29CLOSPI_00564 GH84-CBM32CLOSPI_00638 CBM32-CBM32-GH20-CBM32CLOSPI_00679 CBM32-GH36-CBM32CLOSPI_00716 CE6CLOSPI_00772 GT4CLOSPI_00774 GT4CLOSPI_00775 GT2CLOSPI_00783 GT4CLOSPI_00784 GT4CLOSPI_00797 GH3CLOSPI_00991 GH3CLOSPI_01007 GT4CLOSPI_01011 GT4CLOSPI_01012 GT4CLOSPI_01014 GT4

Clostridium spiroforme (DSM 1552)

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CLOSPI_01048 GH84-CBM32CLOSPI_01078 GT2CLOSPI_01136 GT4CLOSPI_01138 GT4CLOSPI_01338 GH77CLOSPI_01385 GT51CLOSPI_01448 GT2CLOSPI_01468 GH123-GH33CLOSPI_01649 GH20CLOSPI_01650 GH3CLOSPI_01665 GT5CLOSPI_01676 GH84-CBM32CLOSPI_01703 CBM40-CBM40-GH33-CBM32CLOSPI_01729 GH31-CBM35-CBM6-CBM35CLOSPI_01905 CE4CLOSPI_01930 GT4CLOSPI_01931 GT2CLOSPI_01936 GT4CLOSPI_01938 GT4CLOSPI_01964 GT28CLOSPI_01979 CBM32-CBM32-CBM32-GH20-CBM32CLOSPI_02064 GH84-CBM32CLOSPI_02107 CE4CLOSPI_02118 GH84-CBM32CLOSPI_02119 GH20CLOSPI_02120 GH84-CBM32CLOSPI_02126 CBM32CLOSPI_02128 PL8CLOSPI_02157 GH25CLOSPI_02173 GT51CLOSPI_02214 GH3CLOSPI_02218 CBM32-CBM32-CBM32-GH89-CBM32CLOSPI_02219 CBM32-CBM32-GH20-CBM32CLOSPI_02228 CBM32-GH89-CBM32-CBM32-CBM32CLOSPI_02303 CE4CLOSPI_02309 GH31-CBM32-CBM32CLOSPI_02329 GH105CLOSPI_02351 GT4CLOSPI_02353 GT2CLOSPI_02354 GT2CLOSPI_02355 GT2

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CLOSPI_02358 GT2-GT2CLOSPI_02362 GT4CLOSPI_02364 GT2CLOSPI_02366 GT2CLOSPI_02367 GT2CLOSPI_02368 GT14CLOSPI_02375 GH73CLOSPI_02391 CE4CLOSPI_02482 GH2

ORF Name CAZy module(s)COLAER_00008 CBM48-GH13COLAER_00009 GT35COLAER_00012 GT5COLAER_00014 GH13-GH77COLAER_00085 GT2COLAER_00132 GH32COLAER_00140 GT4COLAER_00153 GT2COLAER_00158 GT2COLAER_00159 GT32COLAER_00160 GT4COLAER_00161 GT4COLAER_00336 GT28COLAER_00361 GH1COLAER_00366 GT2COLAER_00484 GH13COLAER_00695 GH73COLAER_00814 GH105COLAER_00819 CE8COLAER_00822 GH28COLAER_00874 GH1COLAER_00878 GH1COLAER_00880 GH1COLAER_00919 GH32COLAER_00921 GH32COLAER_01062 GH13COLAER_01141 GH5COLAER_01347 GT51COLAER_01415 GH4

Collinsella aerofaciens (ATCC 25986)

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COLAER_01643 GT2COLAER_01644 GT2COLAER_01645 GT2COLAER_01646 GT2COLAER_01647 GT2COLAER_01648 GT2-GT2COLAER_01814 CE4COLAER_01858 GH4COLAER_01952 GT35COLAER_01953 GH77COLAER_02077 GT28COLAER_02124 GT2COLAER_02224 CE7COLAER_02225 CE7COLAER_02241 GH23COLAER_02302 GT8COLAER_02303 GT2COLAER_02305 GT2COLAER_02310 GT4COLAER_02339 GH35COLAER_02347 CE9COLAER_02373 GH1

ORF Name CAZy module(s)DORLON_00044 GH43DORLON_00050 GH51DORLON_00207 GH23DORLON_00328 GT35DORLON_00411 GH3DORLON_00446 GT5DORLON_00712 CE4DORLON_00735 CBM48-GH13DORLON_00890 GH32DORLON_00931 GH2DORLON_00969 CE4DORLON_00985 CBM48-GH13DORLON_01015 GT28DORLON_01036 GH18DORLON_01091 GH1DORLON_01327 GH23

Dorea longicatena (DSM 13814)

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DORLON_01522 GH13DORLON_01596 GH1DORLON_01605 GT4DORLON_01608 GT4DORLON_01609 GT2DORLON_01610 GT4DORLON_01611 GT2DORLON_01613 GT2DORLON_01614 GT2DORLON_01616 GT32DORLON_01617 GT2DORLON_01646 GT35DORLON_01673 CE4DORLON_01674 GT28DORLON_01693 CE4DORLON_01696 GT2DORLON_01699 GT2DORLON_01700 GT2-GT2DORLON_01709 GT2DORLON_01718 GT2DORLON_01719 GT2DORLON_01725 GT2DORLON_01726 GT2DORLON_01727 GT2DORLON_01738 GH73DORLON_01739 GH2DORLON_01740 GH25DORLON_01769 GH23DORLON_01807 GH2DORLON_01838 GT51DORLON_01875 GH3DORLON_01880 CE4DORLON_01907 GT4DORLON_01974 GH13DORLON_02096 GT4DORLON_02098 GT2DORLON_02108 GT4DORLON_02111 GT2DORLON_02112 GT2DORLON_02113 GT2DORLON_02232 GH77

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DORLON_02253 GT2DORLON_02261 GH32DORLON_02318 GH77DORLON_02483 GH2DORLON_02536 CE9DORLON_02542 GH13DORLON_02655 GH27DORLON_02674 GH32DORLON_02776 GH32DORLON_02876 CBM48-GH13

ORF Name CAZy module(s)EUBREC_0027 CBM48-GH13EUBREC_0030 GH18EUBREC_0054 GT28EUBREC_0138 GH112EUBREC_0257 GH32EUBREC_0268 CBM2-CBM2EUBREC_0282 GH32EUBREC_0489 GH36EUBREC_0490 GH13EUBREC_0499 GH31EUBREC_0500 GH31EUBREC_0540 GH77EUBREC_0541 GH77EUBREC_0546 GH13EUBREC_0616 GH5EUBREC_0703 GT51EUBREC_0891 GH13EUBREC_0892 GH13EUBREC_1006 GH53EUBREC_1014 GH13EUBREC_1030 GT2EUBREC_1039 CE1EUBREC_1040 GH8EUBREC_1042 GH43EUBREC_1044 GH3EUBREC_1054 GT35EUBREC_1072 GH94EUBREC_1081 GH13

Eubacterium rectale (ATCC 33656)

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EUBREC_1186 CBM34-GH13EUBREC_1308 GH25EUBREC_1317 GH42EUBREC_1385 GH2EUBREC_1386 GH53EUBREC_1456 GH23EUBREC_1773 CE4EUBREC_1819 CBM48-GH13EUBREC_1840 GH77EUBREC_1843 CBM48-GH13EUBREC_1960 GT5EUBREC_2007 GT28EUBREC_2020 GH2EUBREC_2034 GH2EUBREC_2079 GH25-CBM50EUBREC_2169 GT5EUBREC_2308 GH73EUBREC_2389 CE4EUBREC_2426 GT35EUBREC_2453 GH42EUBREC_2454 GH51EUBREC_2506 GT8EUBREC_2507 GT4EUBREC_2518 GT4EUBREC_2519 GT8EUBREC_2520 GT2-GT8EUBREC_2578 GH43EUBREC_2592 GH31EUBREC_2600 CE4EUBREC_2616 GT2EUBREC_2625 GT4EUBREC_2626 GT2EUBREC_2636 GH25EUBREC_2658 GT4EUBREC_2659 GT4EUBREC_2661 + EUBREC_2660 GT1EUBREC_2668 GT2EUBREC_2755 GH24EUBREC_2760 GT2EUBREC_2764 GT2EUBREC_2769 GT2

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EUBREC_2770 GT4EUBREC_2776 GT2EUBREC_2777 GT2EUBREC_2778 GT2EUBREC_2816 GH94EUBREC_2817 GH94EUBREC_2820 GH3EUBREC_2879 GH3EUBREC_2926 CE9EUBREC_2933 GT2EUBREC_2964 CBM48-GH13EUBREC_3074 GT2EUBREC_3151 GT51EUBREC_3295 CBM34-GH13EUBREC_3299 GH25EUBREC_3386 GH36EUBREC_3387 GH36EUBREC_3678 GH13EUBREC_3687 GH1

ORF Name CAZy module(s)FAEPRAM212_00176 GT4FAEPRAM212_00191 GT5FAEPRAM212_00194 CBM48-GH13FAEPRAM212_00241 GT2FAEPRAM212_00403 GT32FAEPRAM212_00408 CE8FAEPRAM212_00433 CBM13FAEPRAM212_00521 GH94FAEPRAM212_00664 GH4FAEPRAM212_00854 GH31FAEPRAM212_00926 GH2FAEPRAM212_00927 GH88FAEPRAM212_00929 GH2FAEPRAM212_00936 GH28FAEPRAM212_00938 GH78FAEPRAM212_00940 GH43-CBM32FAEPRAM212_00941 GH2FAEPRAM212_00943 GH1FAEPRAM212_01007 GH3

Faecalibacterium prausnitzii (M21/2)

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FAEPRAM212_01008 GH3FAEPRAM212_01047 GH77FAEPRAM212_01068 CBM48-GH13FAEPRAM212_01103 GH33FAEPRAM212_01134 GH113FAEPRAM212_01135 CE2FAEPRAM212_01175 GT2FAEPRAM212_01190 GT35FAEPRAM212_01280 GT4FAEPRAM212_01315 GT2-GT2FAEPRAM212_01427 GT51FAEPRAM212_01477 GH13FAEPRAM212_01478 GT35FAEPRAM212_01525 GH2FAEPRAM212_01527 GH36FAEPRAM212_01616 GH77FAEPRAM212_01811 GH4FAEPRAM212_01861 GH2FAEPRAM212_02010 GT2FAEPRAM212_02084 GT2FAEPRAM212_02091 GT2FAEPRAM212_02093 GT2FAEPRAM212_02326 GH1FAEPRAM212_02336 GH1FAEPRAM212_02352 GT4FAEPRAM212_02390 GH2FAEPRAM212_02398 GH1FAEPRAM212_02412 GT28FAEPRAM212_02424 GH2FAEPRAM212_02454 GT2FAEPRAM212_02455 GT4FAEPRAM212_02457 GT2FAEPRAM212_02501 GH25FAEPRAM212_02536 CBM13FAEPRAM212_02542 CE9FAEPRAM212_02883 CE4FAEPRAM212_02886 GH23FAEPRAM212_02931 GT2FAEPRAM212_02932 GT2FAEPRAM212_02933 GT2FAEPRAM212_02936 GT4

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FAEPRAM212_02937 GT26FAEPRAM212_03060 GH2FAEPRAM212_03062 GH112FAEPRAM212_03137 GH28FAEPRAM212_03138 GH105FAEPRAM212_03196 GT4FAEPRAM212_03198 GT4FAEPRAM212_03232 GT2-GT2FAEPRAM212_03233 GT2FAEPRAM212_03254 CBM48-GH13FAEPRAM212_03256 GH13FAEPRAM212_03476 GH13FAEPRAM212_03477 GH105

ORF Name CAZy module(s)LDBUL1632_0078 GT8LDBUL1632_0352 GH25LDBUL1632_0548 GT28LDBUL1632_0605 GH1LDBUL1632_0606 GH1LDBUL1632_0617 GH13LDBUL1632_0620 GT2LDBUL1632_0661 GH1LDBUL1632_0745 GH2LDBUL1632_0755 GT51LDBUL1632_0836 CBM50LDBUL1632_0945 GH18LDBUL1632_1011 GT51LDBUL1632_1051 GH13LDBUL1632_1081 GH1LDBUL1632_1082 GH1LDBUL1632_1177 GT8LDBUL1632_1178 GT8LDBUL1632_1179 GT8LDBUL1632_1193 GT14LDBUL1632_1200 GT2LDBUL1632_1201 GT4LDBUL1632_1327 GT26LDBUL1632_1328 GT4LDBUL1632_1329 GT32

Lactobacillus delbrueckii subsp. bulgaricus (CNCM-1632)

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LDBUL1632_1336 GH73LDBUL1632_1461 GT4LDBUL1632_1462 GT32LDBUL1632_1463 GT32LDBUL1632_1488 GH73LDBUL1632_1514 CE9LDBUL1632_1515 GH31-CBM32LDBUL1632_1518 GH13LDBUL1632_1530 GT2LDBUL1632_1543 CBM50-CBM50LDBUL1632_1575 GT4LDBUL1632_1576 GT4LDBUL1632_1587 GH4LDBUL1632_1689 GH13LDBUL1632_1690 GH13LDBUL1632_1694 GH32LDBUL1632_1752 GT2LDBUL1632_1817 GH25

ORF Name CAZy module(s)LDBUL1519_0023 GH18LDBUL1519_0106 GH1LDBUL1519_0141 GT4LDBUL1519_0142 GT4LDBUL1519_0179 GT8LDBUL1519_0188 GH1LDBUL1519_0199 GH13LDBUL1519_0202 GT2LDBUL1519_0449 GT26LDBUL1519_0450 GT4LDBUL1519_0451 GT32LDBUL1519_0459 GH73LDBUL1519_0531 GH25LDBUL1519_0721 GT51LDBUL1519_0808 GH1LDBUL1519_0809 GH1LDBUL1519_0867 GT51LDBUL1519_1034 GH25-CBM50LDBUL1519_1091 GT28LDBUL1519_1149 GH13

Lactobacillus delbrueckii subsp. bulgaricus (CNCM I-1519)

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LDBUL1519_1150 GH13LDBUL1519_1197 GH25LDBUL1519_1250 GT4LDBUL1519_1251 GT2LDBUL1519_1255 GT14LDBUL1519_1313 GT2LDBUL1519_1375 GT8LDBUL1519_1376 GT8LDBUL1519_1377 GT8LDBUL1519_1526 CBM50-CBM50LDBUL1519_1539 GT2LDBUL1519_1551 GH13LDBUL1519_1552 GH13LDBUL1519_1555 GH31-CBM32LDBUL1519_1556 CE9LDBUL1519_1585 GH73LDBUL1519_1596 GH2LDBUL1519_1602 GH13LDBUL1519_1603 GH13LDBUL1519_1607 GH32LDBUL1519_1655 CBM50LDBUL1519_1696 GT4LDBUL1519_1701 GT1LDBUL1519_1702 GT1LDBUL1519_1743 GT14LDBUL1519_1744 GT4LDBUL1519_1801 GH1

ORF Name CAZy module(s)LLCRE1631_0110 GH23LLCRE1631_0177 GT2LLCRE1631_0178 CE4LLCRE1631_0193 GH77LLCRE1631_0196 GT5LLCRE1631_0197 GT35LLCRE1631_0198 CBM34-GH13LLCRE1631_0274 GH1LLCRE1631_0302 GT4LLCRE1631_0303 GT2LLCRE1631_0307 GT2-GT4

Lactococcus lactis subsp. cremoris (CNCM I-1631)

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LLCRE1631_0309 GT4LLCRE1631_0310 GT2LLCRE1631_0311 GT2LLCRE1631_0312 GT2LLCRE1631_0314 GT2LLCRE1631_0315 GT2LLCRE1631_0316 GT2LLCRE1631_0321 GH25LLCRE1631_0473 GH2LLCRE1631_0505 CBM33LLCRE1631_0506 GH18-CBM5LLCRE1631_0573 GT51LLCRE1631_0635 GH43LLCRE1631_0639 GH92LLCRE1631_0640 GH92LLCRE1631_0642 GH125LLCRE1631_0643 GH38LLCRE1631_0647 GH20LLCRE1631_0648 GH13LLCRE1631_0649 GH85-CBM32LLCRE1631_0651 GH1LLCRE1631_0721 GT2LLCRE1631_0749 GT4LLCRE1631_0819 GH1LLCRE1631_0825 GH65LLCRE1631_0826 GH13LLCRE1631_0827 GH13LLCRE1631_0829 GH13LLCRE1631_0831 CBM34-GH13LLCRE1631_0878 GH1LLCRE1631_0880 GT4LLCRE1631_0910 GH31LLCRE1631_0911 GH31LLCRE1631_0974 CE1LLCRE1631_1005 GT4LLCRE1631_1006 GT4LLCRE1631_1036 GH25-CBM50-CBM50LLCRE1631_1117 GT28LLCRE1631_1313 CE9LLCRE1631_1392 GH73-CBM50-CBM50-CBM50LLCRE1631_1438 GT4

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LLCRE1631_1442 GT4LLCRE1631_1443 GT2LLCRE1631_1444 GT2LLCRE1631_1446 GT4LLCRE1631_1447 GT2LLCRE1631_1503 GT2LLCRE1631_1552 GT2LLCRE1631_1567 GH73LLCRE1631_1601 GH3LLCRE1631_1625 GH65LLCRE1631_1637 GH1LLCRE1631_1669 GT51LLCRE1631_1782 GH1LLCRE1631_1792 GT51LLCRE1631_1794 GH73-CBM50LLCRE1631_1848 CBM48-GH13LLCRE1631_1873 GT2LLCRE1631_2018 GH25LLCRE1631_2065 CE4LLCRE1631_2163 CE4LLCRE1631_2165 GT2LLCRE1631_2266 GH73LLCRE1631_2367 GH1LLCRE1631_2568 GH25-CBM50-CBM50

ORF Name CAZy module(s)BDI_0003 CBM20-CBM20-GH77BDI_0033 GT4BDI_0039 GT4BDI_0042 GT26BDI_0046 GT2BDI_0050 GH20BDI_0060 GH26BDI_0089 GH36BDI_0175 GT2BDI_0209 GT4BDI_0210 GH57BDI_0212 GT5BDI_0230 GH2BDI_0236 CE9

Parabacteroides distasonis (ATCC 8503)

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BDI_0237 CE9BDI_0244 GH38BDI_0301 GT2BDI_0361 GH125BDI_0369 GH3BDI_0437 GT4BDI_0447 GH36BDI_0474 GH2BDI_0528 GT51BDI_0535 GH97BDI_0571 GT4BDI_0575 GT4BDI_0665 GH20BDI_0666 GH92BDI_0819 GH23BDI_0930 GH13BDI_0931 GH13BDI_0932 GT51BDI_0983 GH2BDI_1029 GH23BDI_1056 GT51BDI_1142 GH84BDI_1155 GH109BDI_1208 GH3BDI_1272 GH20BDI_1274 GH51BDI_1281 GT4BDI_1286 GT32BDI_1287 GT2BDI_1293 GH73BDI_1295 GT2BDI_1296 GT2BDI_1297 GT2BDI_1302 GT2BDI_1317 GH78BDI_1318 GH78BDI_1319 GH78BDI_1339 GH43BDI_1344 GT2BDI_1406 GT4BDI_1409 GT4

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BDI_1411 GT2BDI_1422 GH2BDI_1426 GH20BDI_1433 GT2BDI_1469 GT4BDI_1470 GT4BDI_1513 GH73BDI_1518 GH35BDI_1542 GT2BDI_1564 GH51BDI_1576 GT4BDI_1582 GT4BDI_1584 GT2BDI_1618 GH92BDI_1619 GH92BDI_1620 GH92BDI_1627 GH92BDI_1649 GH78BDI_1651 GT2BDI_1673 GH76BDI_1684 GH123BDI_1726 CBM48-GH13BDI_1752 GH43BDI_1756 GH92BDI_1787 GH30BDI_1796 GH78BDI_1818 GT51BDI_1839 GT2BDI_1842 GT4BDI_1844 GT2BDI_1938 GH51BDI_1976 GH2BDI_2004 GT3BDI_2005 GT35BDI_2007 CE1BDI_2023 GT2BDI_2100 GH73-CBM50BDI_2105 CE11BDI_2179 GH43BDI_2183 GH92BDI_2204 GT2

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BDI_2206 GT4BDI_2207 GT4BDI_2211 GT2BDI_2213 GT2BDI_2214 GT2BDI_2216 GT4BDI_2286 CBM9BDI_2288 GT30BDI_2332 GH92BDI_2338 GH3BDI_2400 GH43BDI_2414 GH78BDI_2423 GH95BDI_2427 GH123BDI_2428 GH3BDI_2467 GH28BDI_2487 GT28BDI_2521 GH20BDI_2556 GH23BDI_2636 GT19BDI_2687 CE1BDI_2731 GH92BDI_2739 GH29-CBM32BDI_2743 GH13BDI_2746 GH13BDI_2776 GT4BDI_2778 GT2BDI_2780 GT4BDI_2781 GT4BDI_2785 GT10BDI_2787 GT2BDI_2812 GT2BDI_2813 CE4BDI_2815 GT4BDI_2816 GT4BDI_2819 GT9BDI_2833 GH110BDI_2880 GH97BDI_2922 GT32BDI_2928 GT4BDI_2929 GT2

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BDI_2931 GT2BDI_2946 GH33BDI_2947 GH20BDI_3021 CBM32-GH2BDI_3041 GT2BDI_3060 GH16BDI_3065 GH43-CBM32BDI_3067 GH3BDI_3068 GH3BDI_3069 GH43-CBM32BDI_3071 CE1BDI_3078 CE4BDI_3102 GH31BDI_3103 GH2BDI_3104 GH3BDI_3120 GH2BDI_3121 GH2BDI_3129 GH97BDI_3139 GH78BDI_3140 GH92BDI_3143 GH92BDI_3144 GH92BDI_3145 CE1BDI_3152 CE9BDI_3159 GT32BDI_3166 GT4BDI_3179 GH63BDI_3181 GH92BDI_3206 GT1BDI_3227 GT2BDI_3228 GT4BDI_3229 GT2BDI_3231 GT4BDI_3232 GT2BDI_3233 GT4BDI_3234 GT8BDI_3237 GT4BDI_3296 GH2BDI_3373 GH32BDI_3381 GH2BDI_3387 GH92

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BDI_3446 CBM62BDI_3540 GH13BDI_3541 GH31BDI_3633 CE4BDI_3652 GT2BDI_3774 GH13BDI_3785 GH30BDI_3881 GH24BDI_3926 GH15BDI_3927 GT20BDI_3945 GT2

ORF Name CAZy module(s)RUMOBE_00035 GT4RUMOBE_00036 GT2RUMOBE_00110 GH32RUMOBE_00161 CE4RUMOBE_00330 GH42RUMOBE_00331 GH1RUMOBE_00801 GH78RUMOBE_00804 GH13RUMOBE_00815 GT2RUMOBE_00832 GH13RUMOBE_00846 GT5RUMOBE_00895 GH23RUMOBE_00983 GH18RUMOBE_01251 GT2RUMOBE_01322 GH77RUMOBE_01348 GH23RUMOBE_01573 GT4RUMOBE_01597 GH13RUMOBE_01598 GH13RUMOBE_01613 GT2RUMOBE_01648 GH32RUMOBE_01671 GT28RUMOBE_01755 GH23RUMOBE_01865 GH20RUMOBE_01976 GH36RUMOBE_02005 GT35RUMOBE_02026 CE9

Ruminococcus obeum (ATCC 29174)

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RUMOBE_02027 CE4RUMOBE_02029 CBM48-GH13RUMOBE_02172 GH32RUMOBE_02174 GH32RUMOBE_02176 GH13RUMOBE_02332 GH2RUMOBE_02333 GH42RUMOBE_02421 GH78RUMOBE_02422 GH2RUMOBE_02424 GH3RUMOBE_02431 GH43RUMOBE_02484 GH3RUMOBE_02485 GH3RUMOBE_02503 GH23RUMOBE_02626 CBM48-GH13RUMOBE_02645 GH95RUMOBE_02649 GH112RUMOBE_02657 GH29RUMOBE_02673 GT2RUMOBE_02675 GT2RUMOBE_02676 GT2RUMOBE_02729 GT2RUMOBE_02730 GT2RUMOBE_02795 GT2RUMOBE_02801 GT2RUMOBE_02804 GT4RUMOBE_02805 GT4RUMOBE_02807 GT2RUMOBE_02808 GT4RUMOBE_02815 GT2RUMOBE_02818 GT2RUMOBE_02822 CE4RUMOBE_02883 GH23RUMOBE_02906 GT2RUMOBE_02907 GT2RUMOBE_02940 GH13RUMOBE_03034 CBM48-GH13RUMOBE_03142 GT35RUMOBE_03199 GT2RUMOBE_03200 GT2RUMOBE_03201 GT2

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RUMOBE_03203 + RUMOBE_032 GT1RUMOBE_03321 GH43RUMOBE_03322 GH5RUMOBE_03388 GH13RUMOBE_03555 GH94RUMOBE_03609 GT2-GT2RUMOBE_03610 GT2-GT2RUMOBE_03613 GT2-GT2RUMOBE_03614 GT2RUMOBE_03617 GT2RUMOBE_03624 GT2RUMOBE_03701 GH77RUMOBE_03702 GH77RUMOBE_03706 CBM48-GH13RUMOBE_03746 GT51RUMOBE_03782 GH23RUMOBE_03918 GH13RUMOBE_03919 GH31

ORF Name CAZy module(s)RUMTOR_00068 GT4RUMTOR_00102 GH1RUMTOR_00151 CBM40-GH33RUMTOR_00174 GH18RUMTOR_00354 GH101-CBM32RUMTOR_00394 CE9RUMTOR_00490 GH73RUMTOR_00566 GH13RUMTOR_00577 CE4RUMTOR_00682 GT51RUMTOR_00705 GH73RUMTOR_00751 CBM48-GH13RUMTOR_00787 CBM32-GH89-CBM32RUMTOR_00799 GT51RUMTOR_00845 GT4RUMTOR_00846 GT4RUMTOR_00847 GT26RUMTOR_00850 GT2RUMTOR_00855 GT2RUMTOR_00862 CBM13-CBM13-CBM13-CBM13-CBM13-CBM13

Ruminococcus torques (ATCC 27756)

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RUMTOR_00928 GT5RUMTOR_01114 GH84-CBM32-CBM32RUMTOR_01148 GT2RUMTOR_01163 GH77RUMTOR_01164 GT35RUMTOR_01174 GH51RUMTOR_01193 GH33RUMTOR_01211 GH123-GH33RUMTOR_01223 GT2RUMTOR_01268 CBM32-CBM32-GH20-CBM32RUMTOR_01294 GH95-CBM32RUMTOR_01337 GH25RUMTOR_01416 GT2RUMTOR_01419 CBM32-GH36RUMTOR_01422 CBM48-GH13RUMTOR_01430 CBM32-GH36RUMTOR_01432 GH84-CBM32-CBM32RUMTOR_01473 GH13RUMTOR_01500 GT4RUMTOR_01501 GT2RUMTOR_01504 GT2RUMTOR_01508 GT2RUMTOR_01567 GH25RUMTOR_01582 GH84-CBM32-CBM32RUMTOR_01594 GH101RUMTOR_01626 GH1RUMTOR_01682 GT28RUMTOR_01685 CBM32-GH20RUMTOR_01739 GH1RUMTOR_01856 GH1RUMTOR_01966 GH123RUMTOR_02111 CBM40-GH33-CBM32RUMTOR_02141 GH112RUMTOR_02191 GH2-CBM32RUMTOR_02288 GH95RUMTOR_02294 GH25-CBM50-CBM50RUMTOR_02319 CE4RUMTOR_02460 GH4RUMTOR_02465 GH2RUMTOR_02504 GH1RUMTOR_02528 GH29

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RUMTOR_02566 GH13RUMTOR_02570 GH42RUMTOR_02581 GH20-CBM32RUMTOR_02665 GH18RUMTOR_02677 GT35RUMTOR_02756 GH4RUMTOR_02789 GH31-CBM32-CBM32RUMTOR_02806 CBM32-GH20-CBM32

ORF Name CAZy module(s)STHE1630_01474 GT51STHE1630_01239 GH77STHE1630_00447 CE9STHE1630_01494 GT2-GT8STHE1630_00875 GT2STHE1630_01519 GT2STHE1630_01823 GT2STHE1630_01240 GT35STHE1630_01555 GH25STHE1630_00854 GT28STHE1630_01400 CBM50STHE1630_01827 GT4STHE1630_01706 GH23STHE1630_01497 GT4STHE1630_01513 GT2STHE1630_01514 GT4STHE1630_01054 GT51STHE1630_00650 CE1STHE1630_01821 GT4STHE1630_01824 GT2STHE1630_01825 GT4STHE1630_01826 GT4STHE1630_01869 CE4STHE1630_01870 CE4STHE1630_01791 GH13STHE1630_01793 GH13STHE1630_01805 GH25STHE1630_01496 GT4STHE1630_01488 GH2STHE1630_01511 GT2

Streptococcus thermophilus (CNCM I-1630)

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STHE1630_01515 GT2STHE1630_01516 GT2STHE1630_01620 GH13STHE1630_01621 GH13STHE1630_01224 GT51STHE1630_00943 GH1STHE1630_00944 GH1STHE1630_00872 GT2STHE1630_00534 CE4STHE1630_00535 CE4STHE1630_00444 GH73STHE1630_00538 GH13STHE1630_00539 GH13STHE1630_00497 GH1STHE1630_00498 GH1STHE1630_00499 GH1STHE1630_00500 GH1STHE1630_00413 GH73STHE1630_00374 GT4STHE1630_00375 GT4STHE1630_00342 GH73STHE1630_00343 GH73STHE1630_00152 GH32STHE1630_00040 GT8

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ORFs38555536477946634065

Bacteroides WH2 569116603995246523672970369934931893185025793850417528751893

GH PL 142 9313 24260 16181 1174 7

Bacteroides WH2 381 2238 024 042 222 029 052 039 021 0

Bacteroides caccae (ATCC 43185)Bacteroides ovatus (ATCC 8483)Bacteroides thetaiotaomicron (VPI-5482)Bacteroides uniformis (ATCC 8492)Bacteroides vulgatus (ATCC 8482)

Bifidobacterium animalis subsp. lactis (CNCM I-2494)Clostridium scindens (ATCC 35704)Clostridium spiroforme (DSM 1552)Collinsella aerofaciens (ATCC 25986)Dorea longicatena (DSM 13814)Eubacterium rectale (ATCC 33656)Faecalibacterium prausnitzii (M21/2)Lactobacillus delbrueckii subsp. bulgaricus (CNCM I-1519)Lactobacillus delbrueckii subsp. bulgaricus (CNCM I-1632)Lactococcus lactis subsp. cremoris (CNCM I-1631)Parabacteroides distasonis (ATCC 8503)Ruminococcus obeum (ATCC 29174)Ruminococcus torques (ATCC 27756)Streptococcus thermophilus (CNCM I-1630)

Bacteroides caccae (ATCC 43185)Bacteroides ovatus (ATCC 8483)Bacteroides thetaiotaomicron (VPI-5482)Bacteroides uniformis (ATCC 8492)Bacteroides vulgatus (ATCC 8482)

Bifidobacterium animalis subsp. lactis (CNCM I-2494)Clostridium scindens (ATCC 35704)Clostridium spiroforme (DSM 1552)Collinsella aerofaciens (ATCC 25986)Dorea longicatena (DSM 13814)Eubacterium rectale (ATCC 33656)Faecalibacterium prausnitzii (M21/2)Lactobacillus delbrueckii subsp. bulgaricus (CNCM I-1519)

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19 038 097 046 047 022 0

GH1 GH20 160 370 320 220 25

Bacteroides WH2 0 431 20 10 15 02 41 34 85 15 17 10 111 25 26 1

PL1 PL62 09 05 00 02 0

Bacteroides WH2 6 10 00 00 00 00 0

Lactobacillus delbrueckii subsp. bulgaricus (CNCM I-1632)Lactococcus lactis subsp. cremoris (CNCM I-1631)Parabacteroides distasonis (ATCC 8503)Ruminococcus obeum (ATCC 29174)Ruminococcus torques (ATCC 27756)Streptococcus thermophilus (CNCM I-1630)

Bacteroides caccae (ATCC 43185)Bacteroides ovatus (ATCC 8483)Bacteroides thetaiotaomicron (VPI-5482)Bacteroides uniformis (ATCC 8492)Bacteroides vulgatus (ATCC 8482)

Bifidobacterium animalis subsp. lactis (CNCM I-2494)Clostridium scindens (ATCC 35704)Clostridium spiroforme (DSM 1552)Collinsella aerofaciens (ATCC 25986)Dorea longicatena (DSM 13814)Eubacterium rectale (ATCC 33656)Faecalibacterium prausnitzii (M21/2)Lactobacillus delbrueckii subsp. bulgaricus (CNCM I-1519)Lactobacillus delbrueckii subsp. bulgaricus (CNCM I-1632)Lactococcus lactis subsp. cremoris (CNCM I-1631)Parabacteroides distasonis (ATCC 8503)Ruminococcus obeum (ATCC 29174)Ruminococcus torques (ATCC 27756)Streptococcus thermophilus (CNCM I-1630)

Bacteroides caccae (ATCC 43185)Bacteroides ovatus (ATCC 8483)Bacteroides thetaiotaomicron (VPI-5482)Bacteroides uniformis (ATCC 8492)Bacteroides vulgatus (ATCC 8482)

Bifidobacterium animalis subsp. lactis (CNCM I-2494)Clostridium scindens (ATCC 35704)Clostridium spiroforme (DSM 1552)Collinsella aerofaciens (ATCC 25986)Dorea longicatena (DSM 13814)

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0 00 00 00 00 00 00 00 00 0

CE1 CE21 04 02 16 02 0

Bacteroides WH2 7 10 10 01 00 00 01 00 10 00 01 04 00 00 01 0

CBM2 CBM50 00 00 00 00 0

Bacteroides WH2 0 00 00 0

Eubacterium rectale (ATCC 33656)Faecalibacterium prausnitzii (M21/2)Lactobacillus delbrueckii subsp. bulgaricus (CNCM I-1519)Lactobacillus delbrueckii subsp. bulgaricus (CNCM I-1632)Lactococcus lactis subsp. cremoris (CNCM I-1631)Parabacteroides distasonis (ATCC 8503)Ruminococcus obeum (ATCC 29174)Ruminococcus torques (ATCC 27756)Streptococcus thermophilus (CNCM I-1630)

Bacteroides caccae (ATCC 43185)Bacteroides ovatus (ATCC 8483)Bacteroides thetaiotaomicron (VPI-5482)Bacteroides uniformis (ATCC 8492)Bacteroides vulgatus (ATCC 8482)

Bifidobacterium animalis subsp. lactis (CNCM I-2494)Clostridium scindens (ATCC 35704)Clostridium spiroforme (DSM 1552)Collinsella aerofaciens (ATCC 25986)Dorea longicatena (DSM 13814)Eubacterium rectale (ATCC 33656)Faecalibacterium prausnitzii (M21/2)Lactobacillus delbrueckii subsp. bulgaricus (CNCM I-1519)Lactobacillus delbrueckii subsp. bulgaricus (CNCM I-1632)Lactococcus lactis subsp. cremoris (CNCM I-1631)Parabacteroides distasonis (ATCC 8503)Ruminococcus obeum (ATCC 29174)Ruminococcus torques (ATCC 27756)Streptococcus thermophilus (CNCM I-1630)

Bacteroides caccae (ATCC 43185)Bacteroides ovatus (ATCC 8483)Bacteroides thetaiotaomicron (VPI-5482)Bacteroides uniformis (ATCC 8492)Bacteroides vulgatus (ATCC 8482)

Bifidobacterium animalis subsp. lactis (CNCM I-2494)Clostridium scindens (ATCC 35704)

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0 00 00 02 00 00 00 00 10 00 00 00 0

GT1 GT20 300 240 380 280 32

Bacteroides WH2 0 421 160 120 120 140 201 130 162 40 40 171 321 280 80 10

Notes

Clostridium spiroforme (DSM 1552)Collinsella aerofaciens (ATCC 25986)Dorea longicatena (DSM 13814)Eubacterium rectale (ATCC 33656)Faecalibacterium prausnitzii (M21/2)Lactobacillus delbrueckii subsp. bulgaricus (CNCM I-1519)Lactobacillus delbrueckii subsp. bulgaricus (CNCM I-1632)Lactococcus lactis subsp. cremoris (CNCM I-1631)Parabacteroides distasonis (ATCC 8503)Ruminococcus obeum (ATCC 29174)Ruminococcus torques (ATCC 27756)Streptococcus thermophilus (CNCM I-1630)

Bacteroides caccae (ATCC 43185)Bacteroides ovatus (ATCC 8483)Bacteroides thetaiotaomicron (VPI-5482)Bacteroides uniformis (ATCC 8492)Bacteroides vulgatus (ATCC 8482)

Bifidobacterium animalis subsp. lactis (CNCM I-2494)Clostridium scindens (ATCC 35704)Clostridium spiroforme (DSM 1552)Collinsella aerofaciens (ATCC 25986)Dorea longicatena (DSM 13814)Eubacterium rectale (ATCC 33656)Faecalibacterium prausnitzii (M21/2)Lactobacillus delbrueckii subsp. bulgaricus (CNCM I-1519)Lactobacillus delbrueckii subsp. bulgaricus (CNCM I-1632)Lactococcus lactis subsp. cremoris (CNCM I-1631)Parabacteroides distasonis (ATCC 8503)Ruminococcus obeum (ATCC 29174)Ruminococcus torques (ATCC 27756)Streptococcus thermophilus (CNCM I-1630)

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Notes

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two ORFs make a complete protein (two subunits)

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Notes

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two ORFs make a complete protein (two subunits)

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module CBM58 inserted in the middle of module GH13

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Notes

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Notes

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Notes

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CBM22 modules inserted in the middle of GH10 module

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Notes

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Notes

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Notes

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Notes

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Notes

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Notes

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two ORFs make a complete protein (two subunits)

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Notes

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Notes

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Notes

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Notes

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Notes

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Notes

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two ORFs make a complete protein (two subunits)

Notes

CBM13-CBM13-CBM13-CBM13-CBM13-CBM13

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Notes

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CE CBM GT 8 35 64

32 28 6520 30 8514 23 6918 18 7530 38 843 6 266 5 237 52 335 1 266 3 335 9 314 6 301 5 23

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1 4 215 14 33

11 10 794 4 393 35 196 1 26

GH3 GH4 GH5 GH8 GH9 GH10 GH13 GH1510 0 0 0 0 0 3 021 0 5 0 1 8 5 110 0 0 0 0 0 8 023 0 6 0 6 0 7 15 0 0 0 0 1 4 1

31 0 7 2 3 10 10 03 0 1 0 0 0 14 00 0 0 0 0 0 6 04 0 0 0 0 0 2 00 2 1 0 0 0 4 02 0 0 0 0 0 6 03 0 1 1 0 0 13 02 2 0 0 0 0 6 00 0 0 0 0 0 7 00 1 0 0 0 0 5 01 0 0 0 0 0 7 07 0 0 0 0 0 7 13 0 1 0 0 0 12 00 2 0 0 0 0 5 00 0 0 0 0 0 6 0

PL8 PL9 PL10 PL11 PL12 PL13 PL15 PL174 3 0 0 0 0 0 02 2 1 5 3 1 1 03 2 1 1 2 1 1 01 0 0 0 0 0 0 00 0 2 3 0 0 0 07 0 2 2 1 1 1 10 0 0 0 0 0 0 00 0 0 0 0 0 0 02 0 0 0 0 0 0 00 0 0 0 0 0 0 00 0 0 0 0 0 0 0

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0 0 0 0 0 0 0 00 0 0 0 0 0 0 00 0 0 0 0 0 0 00 0 0 0 0 0 0 00 0 0 0 0 0 0 00 0 0 0 0 0 0 00 0 0 0 0 0 0 00 0 0 0 0 0 0 00 0 0 0 0 0 0 0

CE4 CE6 CE7 CE8 CE9 CE10 CE11 CE121 0 0 2 2 0 1 14 3 3 6 3 0 1 84 1 1 2 3 1 1 44 0 2 0 0 0 1 13 0 1 3 2 0 1 54 2 3 5 1 0 1 52 0 0 0 0 0 0 05 0 0 0 1 0 0 04 1 0 0 1 0 0 01 0 2 1 1 0 0 05 0 0 0 1 0 0 03 0 0 0 1 0 0 01 0 0 1 1 0 0 00 0 0 0 1 0 0 00 0 0 0 1 0 0 03 0 0 0 1 0 0 03 0 0 0 3 0 1 03 0 0 0 1 0 0 02 0 0 0 1 0 0 04 0 0 0 1 0 0 0

CBM6 CBM9 CBM10 CBM13 CBM20 CBM22 CBM23 CBM321 0 0 0 2 0 0 277 0 0 0 2 0 0 90 0 0 0 2 0 0 190 0 0 0 2 0 0 121 1 0 0 2 0 0 97 0 0 3 2 2 0 140 0 1 0 0 0 1 00 0 0 0 0 0 0 1

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5 0 0 0 0 0 0 410 0 0 0 0 0 0 00 0 0 0 0 0 0 00 0 0 0 0 0 0 00 0 0 2 0 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 0 10 1 0 0 2 0 0 40 0 0 0 0 0 0 00 0 0 6 0 0 0 230 0 0 0 0 0 0 0

GT3 GT4 GT5 GT6 GT8 GT9 GT10 GT111 16 1 1 1 1 0 21 19 1 2 0 2 0 41 27 1 0 1 1 0 01 24 1 0 0 1 0 11 23 1 0 0 1 0 21 27 1 0 0 1 0 00 4 0 0 0 0 0 00 5 1 0 0 0 0 00 15 1 0 0 0 0 00 4 1 0 1 0 0 00 6 1 0 0 0 0 00 6 2 0 3 0 0 00 7 1 0 0 0 0 00 6 0 0 4 0 0 00 5 0 0 4 0 0 00 10 1 0 0 0 0 01 28 1 0 1 1 1 00 5 1 0 0 0 0 00 4 1 0 0 0 0 00 9 0 0 2 0 0 0

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GH16 GH18 GH20 GH23 GH24 GH25 GH26 GH277 0 12 3 0 1 0 15 9 13 3 0 1 3 34 12 14 3 0 1 0 51 3 5 3 0 1 3 01 2 8 3 0 1 0 15 3 7 3 1 1 5 40 0 0 0 0 2 0 00 2 0 2 0 2 0 00 0 5 0 0 2 0 00 0 0 1 0 0 0 00 1 0 3 0 1 0 10 1 0 1 1 4 0 00 0 0 1 0 1 0 00 1 0 0 0 3 0 00 1 0 0 0 2 0 00 1 1 1 0 4 0 01 0 6 3 1 0 1 00 1 1 6 0 0 0 00 2 4 0 0 3 0 00 0 0 1 0 2 0 0

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CE1500001100000000000000

CBM33 CBM34 CBM35 CBM38 CBM40 CBM48 CBM50 CBM510 0 1 0 0 2 2 00 0 3 0 0 2 2 00 0 0 0 0 3 2 10 0 1 2 0 2 3 00 0 1 0 0 2 1 00 0 0 0 0 4 3 20 0 0 0 0 4 0 00 0 0 0 0 3 1 0

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0 0 2 0 2 2 0 00 0 0 0 0 1 0 00 0 0 0 0 3 0 00 2 0 0 0 4 1 00 0 0 0 0 3 0 00 0 0 0 0 0 4 00 0 0 0 0 0 3 01 2 0 0 0 1 8 00 0 0 0 0 1 1 00 0 0 0 0 4 0 00 0 0 0 2 2 2 00 0 0 0 0 0 1 0

GT14 GT19 GT20 GT25 GT26 GT28 GT30 GT320 1 1 0 0 1 1 10 1 1 0 2 1 1 03 1 0 1 0 1 1 31 1 1 0 2 1 1 12 1 1 0 4 1 1 00 1 0 0 1 1 1 20 0 0 0 0 0 0 10 0 0 0 0 2 0 01 0 0 0 0 1 0 00 0 0 0 0 2 0 10 0 0 0 0 2 0 10 0 0 0 0 2 0 00 0 0 0 1 1 0 12 0 0 0 1 1 0 11 0 0 0 1 1 0 30 0 0 0 0 1 0 00 1 1 0 1 1 1 30 0 0 0 0 1 0 00 0 0 0 1 1 0 00 0 0 0 0 1 0 0

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GH28 GH29 GH30 GH31 GH32 GH33 GH35 GH363 12 1 4 2 3 5 2

14 7 4 11 2 4 2 39 9 3 6 4 2 3 42 2 3 6 4 1 1 1

13 8 5 4 1 3 1 325 9 9 10 2 2 3 40 0 2 0 1 0 0 30 1 0 0 0 0 0 00 3 0 2 1 2 0 21 0 0 0 3 0 1 00 0 0 0 4 0 0 00 0 0 3 2 0 0 32 0 0 1 0 1 0 10 0 0 1 1 0 0 00 0 0 1 1 0 0 00 0 0 2 0 0 0 01 1 2 2 1 1 1 20 1 0 1 4 0 0 10 1 0 1 0 4 0 20 0 0 0 1 0 0 0

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CBM57 CBM58 CBM620 0 03 0 01 1 11 0 01 0 01 0 00 0 00 0 0

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0 0 00 0 00 0 00 0 00 0 00 0 00 0 00 0 00 0 10 0 00 0 00 0 0

GT35 GT39 GT51 GT831 0 4 11 0 4 12 0 4 02 0 2 12 0 2 11 0 4 11 1 2 02 0 1 01 0 2 02 0 1 02 0 1 02 0 2 02 0 1 00 0 2 00 0 2 01 0 3 01 0 4 02 0 1 02 0 2 01 0 3 0

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GH38 GH39 GH42 GH43 GH50 GH51 GH53 GH550 0 0 8 0 2 1 01 0 1 35 3 4 1 02 0 1 33 0 4 1 02 0 1 16 0 3 1 20 0 1 22 0 3 0 02 1 3 49 2 9 1 00 0 2 3 0 1 0 00 0 1 0 0 0 0 00 0 0 0 0 0 0 00 0 0 0 0 0 0 00 0 0 1 0 1 0 00 0 2 2 0 1 2 00 0 0 1 0 0 0 00 0 0 0 0 0 0 00 0 0 0 0 0 0 01 0 0 1 0 0 0 01 0 0 6 0 3 0 00 0 2 2 0 0 0 00 0 1 0 0 1 0 00 0 0 0 0 0 0 0

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GH57 GH63 GH65 GH66 GH67 GH68 GH73 GH741 0 0 0 0 0 1 01 0 0 1 2 0 2 01 0 0 1 1 0 1 01 3 1 1 0 0 1 11 2 0 0 1 0 1 01 3 2 1 2 0 1 00 0 0 0 0 0 0 00 0 2 0 0 2 2 00 0 0 0 0 0 1 00 0 0 0 0 0 1 00 0 0 0 0 0 1 00 0 0 0 0 0 1 00 0 0 0 0 0 0 00 0 0 0 0 0 2 00 0 0 0 0 0 2 00 0 2 0 0 0 4 01 1 0 0 0 0 3 00 0 0 0 0 0 0 00 0 0 0 0 0 2 00 0 0 0 0 0 4 0

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GH76 GH77 GH78 GH79 GH84 GH85 GH88 GH890 1 2 0 1 0 6 38 1 8 0 0 0 8 4

10 1 6 0 1 0 4 35 1 3 0 1 0 1 00 1 5 0 1 0 3 11 1 11 1 0 0 8 20 2 0 0 0 0 0 00 2 0 0 0 0 0 00 1 0 0 7 0 0 20 2 0 0 0 0 0 00 2 0 0 0 0 0 00 3 0 0 0 0 0 00 2 1 0 0 0 1 00 0 0 0 0 0 0 00 0 0 0 0 0 0 00 1 0 0 0 1 0 01 1 7 0 1 0 0 00 3 2 0 0 0 0 00 1 0 0 3 0 0 10 1 0 0 0 0 0 0

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GH91 GH92 GH93 GH94 GH95 GH97 GH98 GH992 5 0 0 4 4 0 02 19 0 0 7 12 1 00 24 1 0 5 10 0 10 10 0 1 1 9 0 00 9 0 0 4 7 0 00 14 0 0 12 15 0 00 0 0 1 0 0 0 00 0 0 0 0 0 0 00 4 0 0 0 0 0 00 0 0 0 0 0 0 00 0 0 0 0 0 0 00 0 0 3 0 0 0 00 0 0 1 0 0 0 00 0 0 0 0 0 0 00 0 0 0 0 0 0 00 2 0 0 0 0 0 00 14 0 0 1 3 0 00 0 0 1 1 0 0 00 0 0 0 2 0 0 00 0 0 0 0 0 0 0

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GH101 GH105 GH106 GH108 GH109 GH110 GH112 GH1130 5 1 0 4 2 0 00 12 4 0 2 0 0 00 7 3 0 2 2 0 00 2 0 1 3 0 0 00 8 3 0 5 2 0 00 20 6 1 3 3 0 00 0 0 0 0 0 0 00 0 0 0 0 0 1 00 1 0 0 0 0 0 00 1 0 0 0 0 0 00 0 0 0 0 0 0 00 0 0 0 0 0 1 00 2 0 0 0 0 1 10 0 0 0 0 0 0 00 0 0 0 0 0 0 00 0 0 0 0 0 0 00 0 0 0 1 1 0 00 0 0 0 0 0 1 02 0 0 0 0 0 1 00 0 0 0 0 0 0 0

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GH115 GH116 GH117 GH120 GH123 GH1250 1 0 1 2 08 0 0 0 1 32 0 0 0 1 31 1 0 0 0 73 0 0 0 1 04 1 1 0 0 10 0 0 0 0 00 0 0 0 0 00 0 0 0 2 00 0 0 0 0 00 0 0 0 0 00 0 0 0 0 00 0 0 0 0 00 0 0 0 0 00 0 0 0 0 00 0 0 0 0 10 0 0 0 2 10 0 0 0 0 00 0 0 0 2 00 0 0 0 0 0

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Table S5. COPRO-Seq analysis of bacterial species abundance in mouse fecal samples.

A. Proportional representation of the 20 bacterial species in this study in mouse fecal samples as measured by COPRO-Seq.

Mouse Day

01 01 Single 0.14203 0.0789002 01 Single 0.28479 0.1872403 01 Single 0.27308 0.1924704 01 Single 0.53556 0.0337805 01 Single 0.31645 0.0720406 01 Multiple 0.34762 0.0826507 01 Multiple 0.24150 0.0270508 01 Multiple 0.31288 0.0341309 01 Multiple 0.35867 0.0705010 01 Multiple 0.42808 0.0335901 02 Single 0.19798 0.1620902 02 Single 0.18812 0.1749703 02 Single 0.18367 0.0903704 02 Single 0.30592 0.0638505 02 Single 0.24137 0.1057906 02 Multiple 0.29834 0.0957007 02 Multiple 0.20705 0.1150008 02 Multiple 0.21140 0.0774709 02 Multiple 0.20317 0.0648610 02 Multiple 0.20433 0.0683301 03 Single 0.15255 0.1723902 03 Single 0.15372 0.1322203 03 Single 0.14935 0.0966804 03 Single 0.21548 0.1085805 03 Single 0.22825 0.1076806 03 Multiple 0.18581 0.0959707 03 Multiple 0.17267 0.0942808 03 Multiple 0.18230 0.0800209 03 Multiple 0.18470 0.0768710 03 Multiple 0.19143 0.0663501 07 Single 0.09329 0.1141602 07 Single 0.08236 0.1068203 07 Single 0.10221 0.0985104 07 Single 0.10135 0.0949205 07 Single 0.10683 0.0880106 07 Multiple 0.09232 0.11726

A limit of detection cutoff of 0.00003 (0.003%) has been applied to the data below

Treatment Group

B. caccae(ATCC 43185)

B. ovatus(ATCC 8483)

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07 07 Multiple 0.09621 0.0867308 07 Multiple 0.08439 0.1157609 07 Multiple 0.10676 0.0952410 07 Multiple 0.10898 0.0728701 14 Single 0.06347 0.0987102 14 Single 0.06940 0.1110103 14 Single 0.09037 0.1069804 14 Single 0.09273 0.0936005 14 Single 0.02595 0.0965406 14 Multiple 0.06526 0.1027507 14 Multiple 0.07500 0.1067308 14 Multiple 0.05176 0.0864009 14 Multiple 0.05254 0.0934310 14 Multiple 0.05554 0.0852901 16 Single 0.03953 0.0956902 16 Single 0.06046 0.1561303 16 Single 0.07108 0.1127904 16 Single 0.08444 0.1003505 16 Single 0.02933 0.1192506 16 Multiple 0.03846 0.1343007 16 Multiple 0.05641 0.1109608 16 Multiple 0.05944 0.1143709 16 Multiple 0.05771 0.1085310 16 Multiple 0.03890 0.0894001 17 Single 0.04640 0.1044802 17 Single 0.05708 0.1613203 17 Single 0.06450 0.1172004 17 Single 0.08153 0.0962205 17 Single 0.03472 0.1177306 17 Multiple 0.04190 0.1380607 17 Multiple 0.05819 0.1322908 17 Multiple 0.05693 0.1248709 17 Multiple 0.06183 0.1208110 17 Multiple 0.03117 0.0942301 21 Single 0.06629 0.1266502 21 Single 0.05018 0.1620303 21 Single 0.06358 0.1376604 21 Single 0.07493 0.1418005 21 Single 0.05477 0.1406606 21 Multiple 0.05775 0.1486407 21 Multiple 0.04030 0.1440108 21 Multiple 0.05602 0.1202509 21 Multiple 0.06679 0.1379710 21 Multiple 0.06919 0.12145

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06 23 Multiple 0.04790 0.1360807 23 Multiple 0.04127 0.1394908 23 Multiple 0.05624 0.1347409 23 Multiple 0.06157 0.1256810 23 Multiple 0.07136 0.1035906 24 Multiple 0.04506 0.1311707 24 Multiple 0.04816 0.1131408 24 Multiple 0.05644 0.1489109 24 Multiple 0.05881 0.1093210 24 Multiple 0.06517 0.0938101 28 Single 0.06598 0.1100702 28 Single 0.04151 0.1683303 28 Single 0.05826 0.1408904 28 Single 0.06043 0.1230605 28 Single 0.05337 0.2257706 28 Multiple 0.04403 0.1429107 28 Multiple 0.05712 0.1213008 28 Multiple 0.05380 0.1979409 28 Multiple 0.06376 0.1439510 28 Multiple 0.06045 0.1207901 35 Single 0.05691 0.1193502 35 Single 0.05698 0.1666003 35 Single 0.05555 0.1333804 35 Single 0.05612 0.1485805 35 Single 0.04596 0.1477206 35 Multiple 0.04322 0.1916507 35 Multiple 0.04263 0.1565708 35 Multiple 0.05160 0.1346909 35 Multiple 0.05768 0.2010210 35 Multiple 0.06921 0.1356106 37 Multiple 0.04226 0.1948307 37 Multiple 0.03901 0.1481008 37 Multiple 0.05428 0.1397209 37 Multiple 0.04694 0.1737210 37 Multiple 0.06246 0.1388906 38 Multiple 0.03931 0.1691507 38 Multiple 0.04412 0.1560908 38 Multiple 0.05061 0.1554409 38 Multiple 0.04873 0.1848810 38 Multiple 0.06869 0.1348401 42 Single 0.05878 0.1309402 42 Single 0.04125 0.1166203 42 Single 0.05383 0.1352604 42 Single 0.04777 0.15069

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05 42 Single 0.02463 0.0850706 42 Multiple 0.03612 0.1692807 42 Multiple 0.04074 0.1262208 42 Multiple 0.04163 0.1020409 42 Multiple 0.05768 0.1854510 42 Multiple 0.05984 0.1471601 C Single 0.04619 0.0896902 C Single 0.04306 0.1129203 C Single 0.04696 0.1075304 C Single 0.04503 0.1456605 C Single 0.02632 0.0903606 C Multiple 0.02960 0.1135207 C Multiple 0.03533 0.1050808 C Multiple 0.04065 0.0974409 C Multiple 0.05684 0.1383010 C Multiple 0.04779 0.09217

B. Statistical significance and fold-change of differences in pairwise comparisons of abundance calculated from data in (A).

p-values, Welch's t-test (relative to day 14)

Day

16 Single 0.48873 0.2279316 Multiple 0.16804 0.0900717 Single 0.45067 0.1881517 Multiple 0.21077 0.0191821 Single 0.63669 0.0007021 Multiple 0.77406 0.0007923 Multiple 0.54464 0.0039424 Multiple 0.38535 0.0614828 Single 0.37289 0.0626528 Multiple 0.47678 0.0202635 Single 0.31021 0.0039135 Multiple 0.31421 0.0058237 Multiple 0.11026 0.0024938 Multiple 0.18459 0.0004342 Single 0.13715 0.1147542 Multiple 0.08678 0.02379

Fold-changes (relative to d14)

Treatment Group

B. caccae(ATCC 43185)

B. ovatus(ATCC 8483)

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Day

16 Single -1.20041 1.1526616 Multiple -1.19601 1.1748117 Single -1.20299 1.1778217 Multiple -1.20028 1.2858621 Single -1.10387 1.3985021 Multiple -1.03466 1.4165823 Multiple -1.07821 1.3476224 Multiple -1.09670 1.2565228 Single -1.22314 1.5155228 Multiple -1.07502 1.5315535 Single -1.25933 1.4119635 Multiple -1.13528 1.7268237 Multiple -1.22523 1.6756538 Multiple -1.19342 1.6864742 Single -1.51118 1.2204542 Multiple -1.27154 1.53847

Treatment Group

B. caccae(ATCC 43185)

B. ovatus(ATCC 8483)

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A. Proportional representation of the 20 bacterial species in this study in mouse fecal samples as measured by COPRO-Seq.

0.01101 0.06767 0.533420.01459 0.04249 0.199530.01183 0.02740 0.176310.00933 0.03449 0.285820.01967 0.03232 0.316260.00863 0.03099 0.405420.00882 0.03354 0.534310.00899 0.03432 0.493760.01932 0.02028 0.303260.00975 0.01628 0.338340.04820 0.02330 0.092240.05861 0.03452 0.069660.04320 0.02367 0.059640.03689 0.03727 0.196000.04779 0.03204 0.119250.02844 0.02696 0.145650.03905 0.04430 0.183280.03214 0.01837 0.134950.03261 0.00716 0.158480.02725 0.01070 0.132230.07304 0.02794 0.075270.07412 0.02075 0.071350.06778 0.02277 0.070490.05626 0.02025 0.112090.07271 0.01969 0.067150.04082 0.02457 0.160160.05508 0.02085 0.124870.05412 0.01829 0.112900.05958 0.01627 0.128660.04557 0.01266 0.108360.11236 0.04384 0.113180.09908 0.02733 0.133840.10704 0.03430 0.159170.12166 0.03105 0.138730.11771 0.03221 0.127970.10850 0.03636 0.12453

B. thetaiotaomicron(VPI-5482)

B. uniformis(ATCC 8492)

B. vulgatus(ATCC 8482)

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0.10864 0.03521 0.110480.10555 0.04292 0.121200.11413 0.02068 0.129570.11800 0.02600 0.131500.08905 0.06052 0.193590.07847 0.07381 0.169490.07491 0.06993 0.180840.08348 0.06596 0.199430.09876 0.08329 0.224020.10176 0.07316 0.134480.09192 0.06617 0.137700.07649 0.06642 0.204530.07655 0.05429 0.213520.08305 0.06088 0.208280.09677 0.08541 0.227780.10287 0.07360 0.191000.08197 0.07084 0.227460.09241 0.07216 0.211080.09662 0.08761 0.214610.09736 0.06710 0.152280.09041 0.07276 0.184440.07661 0.05817 0.208600.08894 0.05518 0.214770.08452 0.04812 0.235130.09364 0.10184 0.220560.08348 0.06883 0.191560.08134 0.06085 0.244500.08812 0.06122 0.231050.09167 0.08463 0.207600.10137 0.05783 0.161500.08366 0.06694 0.176810.06858 0.06742 0.199910.08825 0.05144 0.202310.08756 0.05898 0.243980.09226 0.07230 0.200900.08606 0.06637 0.175120.08917 0.10116 0.201150.09095 0.06104 0.195680.08865 0.12562 0.158220.09452 0.06249 0.165510.09379 0.09133 0.148610.07762 0.08561 0.176590.08407 0.09098 0.173810.09960 0.10814 0.21218

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0.09976 0.07134 0.163820.08936 0.08159 0.155780.08325 0.04429 0.196240.08595 0.10208 0.183390.08607 0.08894 0.196430.09564 0.05693 0.190930.09748 0.08421 0.192270.09473 0.04774 0.181950.08040 0.11298 0.212630.07948 0.08395 0.234020.10287 0.02662 0.248680.09270 0.03566 0.185360.07927 0.04079 0.174190.08794 0.09323 0.206250.13425 0.11585 0.186080.11744 0.05668 0.163240.09911 0.09826 0.156420.13714 0.05756 0.204460.09553 0.08858 0.158510.08344 0.06328 0.180450.12294 0.07602 0.178490.09502 0.05045 0.162370.11624 0.09435 0.174140.07982 0.02850 0.236290.11918 0.07306 0.178680.12930 0.07581 0.185300.11531 0.08798 0.199230.09789 0.02690 0.209580.10971 0.05764 0.240520.08374 0.08514 0.171140.12230 0.05928 0.145510.11003 0.06624 0.181800.10418 0.02007 0.217640.10171 0.09811 0.194830.08591 0.04034 0.173810.13407 0.06099 0.159840.11494 0.04761 0.161090.10069 0.02414 0.201970.10267 0.09477 0.195780.08635 0.02765 0.183710.13805 0.02467 0.183400.09446 0.04644 0.223500.10447 0.08170 0.191860.10919 0.07384 0.27075

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0.10052 0.05342 0.313290.12473 0.05504 0.147480.11372 0.04373 0.171630.10267 0.03918 0.242520.10738 0.04876 0.155240.09758 0.08510 0.152270.10803 0.01937 0.248000.08472 0.04144 0.213930.09785 0.06859 0.237110.09726 0.05342 0.338420.10389 0.05629 0.265310.10847 0.05695 0.203090.09526 0.03996 0.212430.09494 0.03397 0.232200.09723 0.03038 0.192860.07120 0.08379 0.19369

B. Statistical significance and fold-change of differences in pairwise comparisons of abundance calculated from data in (A).

0.13110 0.20495 0.108060.79358 0.48931 0.422800.59192 0.60637 0.084800.99243 0.42488 0.471400.35278 0.30876 0.578260.54566 0.02926 0.839510.62177 0.24691 0.977940.58234 0.33084 0.304100.21753 0.66971 0.692390.09967 0.38594 0.735570.05838 0.62679 0.651450.05448 0.83935 0.349940.04011 0.60975 0.892280.05484 0.37022 0.970240.02913 0.23246 0.160100.00883 0.30916 0.82101

B. thetaiotaomicron(VPI-5482)

B. uniformis(ATCC 8492)

B. vulgatus(ATCC 8482)

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1.10823 1.10213 1.108101.01879 -1.06499 1.107631.03195 1.06747 1.13222-1.00082 -1.06052 1.095721.05277 1.20645 -1.038991.04614 1.36654 -1.024881.03404 1.20977 -1.003181.04181 1.20219 1.126091.17035 -1.13252 1.034291.23942 1.13536 -1.041051.25554 -1.09655 -1.040211.24709 1.03910 1.119381.21956 -1.12987 1.016781.25351 -1.25774 1.004311.28732 -1.26221 1.222681.27067 -1.18070 -1.03378

B. thetaiotaomicron(VPI-5482)

B. uniformis(ATCC 8492)

B. vulgatus(ATCC 8482)

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B. WH2

0.15844 0.00066 0.000070.21060 0.00089 0.000120.21532 0.00063 0.000030.08976 0.00019 0.000130.14417 0.00294 0.000200.10927 0.00043 0.000180.11343 0.00283 0.000730.09126 0.00106 0.000180.19802 0.00026 0.000160.12668 0.00184 0.000050.40833 0.00384 0.004070.41928 0.00117 0.001000.55811 0.00210 0.000430.33020 0.00555 0.001970.38861 0.00334 0.000520.32601 0.00815 0.002770.35100 0.00265 0.000430.48579 0.00207 0.000260.47227 0.00138 0.000390.47720 0.00270 0.000440.41237 0.00958 0.007800.47970 0.00244 0.001870.52128 0.00479 0.002370.45167 0.00250 0.002050.47257 0.00077 0.000390.43175 0.00327 0.002500.46875 0.00213 0.000940.49777 0.00298 0.001650.47092 0.00239 0.001820.47356 0.00277 0.002500.44939 0.00598 0.002160.45062 0.00366 0.002130.39035 0.00696 0.003610.46091 0.00292 0.001090.46200 0.00393 0.002370.42799 0.00889 0.00219

C. aerofaciens(ATCC 25986)

C. scindens(ATCC 35704)

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0.42804 0.01894 0.005840.41557 0.01251 0.004370.45576 0.00365 0.004100.43683 0.01154 0.006850.38577 0.02002 0.006570.38712 0.00565 0.004920.39236 0.00719 0.004350.39308 0.00862 0.005190.36920 0.01425 0.006180.41109 0.01785 0.007660.42571 0.01729 0.005370.38430 0.02707 0.009320.41240 0.01115 0.006130.39881 0.01273 0.005490.39276 0.00661 0.005030.33960 0.00358 0.003730.39878 0.00426 0.003050.39303 0.00606 0.003930.37558 0.00745 0.004630.42796 0.00735 0.006810.41504 0.00931 0.002670.39644 0.00569 0.006500.39540 0.00715 0.006640.34812 0.02301 0.019120.38336 0.00422 0.003960.34825 0.00374 0.005440.40223 0.00276 0.002460.37435 0.00737 0.006760.39874 0.00436 0.005650.42559 0.00592 0.005330.40496 0.00787 0.003650.40711 0.00498 0.006240.39174 0.00675 0.006790.38258 0.01577 0.014220.38550 0.00347 0.002660.38296 0.00312 0.002970.36021 0.00376 0.002750.39492 0.00156 0.002570.36238 0.00676 0.004530.40640 0.00200 0.004600.40405 0.00733 0.004490.38935 0.00691 0.008390.37358 0.00645 0.006890.23780 0.02230 0.02132

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0.40694 0.00509 0.004190.39588 0.00900 0.005940.39209 0.00482 0.006300.37305 0.00523 0.003560.37199 0.00548 0.005640.40800 0.00213 0.003440.40905 0.00241 0.001290.37711 0.00828 0.003480.35263 0.00751 0.004390.38256 0.00741 0.004810.38458 0.00265 0.003030.35872 0.00317 0.003070.40821 0.00405 0.004280.37341 0.00200 0.004120.20348 0.00382 0.002670.39348 0.00371 0.004360.39725 0.00613 0.003170.24536 0.00363 0.003950.38956 0.00481 0.003990.40738 0.00906 0.006240.37108 0.00145 0.003580.31937 0.00198 0.006040.31920 0.00310 0.007770.37371 0.00198 0.005480.34333 0.00195 0.005980.28933 0.00139 0.006440.31524 0.00184 0.005130.36851 0.00439 0.010180.23494 0.00247 0.007370.35137 0.00406 0.010950.32035 0.00133 0.011080.36879 0.00229 0.004130.36886 0.00109 0.005800.30086 0.00260 0.006730.37742 0.00468 0.007640.34663 0.00238 0.004250.37730 0.00485 0.005650.38057 0.00111 0.004880.30160 0.00183 0.003450.38005 0.00315 0.007250.36845 0.00121 0.003730.36276 0.00273 0.005010.33201 0.00179 0.002760.18903 0.00925 0.01376

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0.33125 0.00378 0.002950.35786 0.00260 0.004120.40650 0.00229 0.002950.38927 0.00242 0.001520.35993 0.00225 0.004950.35957 0.00191 0.008870.36126 0.00670 0.010410.37060 0.00099 0.006860.32519 0.00159 0.006620.20613 0.00210 0.009460.34336 0.00523 0.005800.35500 0.00974 0.013330.39090 0.00412 0.008390.38291 0.00489 0.009930.38223 0.00263 0.008740.33386 0.00713 0.01857

B. WH2

0.65240 0.10432 0.035210.54150 0.15101 0.616650.71282 0.06438 0.515520.69846 0.03253 0.825410.33746 0.04653 0.002800.23831 0.10292 0.502490.09425 0.01309 0.111910.14764 0.00983 0.009550.33746 0.03838 0.005390.26504 0.01042 0.030540.02445 0.02649 0.689110.01378 0.00564 0.391540.01426 0.00494 0.844190.02855 0.00528 0.125900.10387 0.04868 0.929240.03307 0.00576 0.15807

C. aerofaciens(ATCC 25986)

C. scindens(ATCC 35704)

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B. WH2

-1.01462 -1.99315 -1.33599-1.02489 -1.63938 1.22915-1.01080 -2.48233 -1.12103-1.01011 -2.08507 1.06725-1.02204 -2.98556 -1.75832-1.12210 -1.91358 1.34567-1.04761 -2.90662 -1.32469-1.05337 -3.10265 -1.95094-1.11521 -3.55045 -1.58538-1.10872 -3.14934 -1.56443-1.11632 -5.32717 1.06035-1.30328 -6.08542 1.17964-1.17050 -7.18569 1.04146-1.13781 -6.46681 -1.33347-1.21726 -2.97022 1.03645-1.08498 -7.49634 -1.51485

C. aerofaciens(ATCC 25986)

C. scindens(ATCC 35704)

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0.00010 0.00402 0.000000.00004 0.01242 0.000000.00005 0.00725 0.000000.00010 0.00322 0.000000.00018 0.02302 0.000000.00006 0.00501 0.000000.00021 0.01344 0.000050.00004 0.00410 0.000000.00107 0.00550 0.000000.00065 0.00963 0.000000.00017 0.00005 0.000000.00000 0.00421 0.004190.00000 0.00359 0.005460.00044 0.00138 0.000000.00000 0.00549 0.000000.00037 0.00059 0.000000.00008 0.00390 0.000000.00050 0.01554 0.000000.00145 0.02111 0.000000.00136 0.02471 0.000090.00026 0.00003 0.000040.00000 0.00874 0.009340.00006 0.00840 0.019770.00038 0.00004 0.000000.00000 0.00179 0.000000.00054 0.00000 0.000000.00010 0.00634 0.000000.00064 0.01181 0.000000.00071 0.00840 0.000000.00110 0.01938 0.012780.00000 0.00000 0.000000.00000 0.00315 0.023950.00000 0.00469 0.011460.00000 0.00000 0.000000.00000 0.00239 0.000000.00000 0.00000 0.00000

C. spiroforme(DSM 1552)

D. longicatena(DSM 13814)

E. rectale(ATCC 33656)

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0.00000 0.00554 0.000000.00003 0.00300 0.000000.00004 0.00358 0.000000.00005 0.00961 0.005700.00000 0.00000 0.000000.00000 0.00641 0.036620.00000 0.00514 0.006320.00000 0.00000 0.000000.00000 0.00494 0.000000.00000 0.00000 0.000000.00000 0.00587 0.000000.00000 0.00474 0.000000.00000 0.00424 0.000000.00000 0.00507 0.011360.00000 0.00000 0.000000.00000 0.00177 0.022940.00000 0.00291 0.002220.00000 0.00000 0.000000.00000 0.00311 0.000000.00000 0.00000 0.000000.00000 0.00291 0.000000.00000 0.00441 0.000000.00000 0.00339 0.000000.00000 0.01437 0.011470.00000 0.00000 0.000000.00000 0.00534 0.018710.00000 0.00168 0.001850.00000 0.00000 0.000000.00000 0.00377 0.000000.00000 0.00000 0.000000.00000 0.00527 0.000000.00000 0.00534 0.000000.00000 0.00561 0.000000.00000 0.00890 0.003570.00000 0.00000 0.000000.00000 0.00198 0.018280.00000 0.00209 0.003010.00000 0.00000 0.000000.00000 0.00735 0.000000.00000 0.00000 0.000000.00000 0.00401 0.000000.00000 0.00566 0.000000.00000 0.00435 0.000000.00000 0.01503 0.01134

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0.00000 0.00000 0.000000.00000 0.00630 0.000180.00000 0.00402 0.000000.00000 0.00266 0.000000.00000 0.00456 0.009250.00000 0.00000 0.000000.00000 0.00061 0.000000.00000 0.00218 0.000000.00000 0.00197 0.000000.00000 0.00296 0.010140.00000 0.00000 0.000000.00000 0.00282 0.043160.00000 0.00286 0.033490.00000 0.00000 0.000000.00000 0.00165 0.000000.00000 0.00000 0.000000.00000 0.00311 0.000000.00000 0.00158 0.000000.00000 0.00287 0.000000.00000 0.00578 0.020230.00000 0.00000 0.000120.00000 0.00323 0.055840.00000 0.00348 0.030070.00000 0.00000 0.000000.00000 0.00277 0.000000.00000 0.00000 0.000000.00000 0.00360 0.000000.00000 0.00496 0.000000.00000 0.00327 0.000000.00000 0.00605 0.024590.00003 0.00000 0.000000.00000 0.00253 0.000000.00000 0.00153 0.000000.00000 0.00276 0.000000.00000 0.00373 0.041180.00000 0.00000 0.000000.00000 0.00449 0.000000.00000 0.00276 0.000000.00000 0.00204 0.000000.00000 0.00407 0.036590.00000 0.00000 0.000000.00000 0.00215 0.024160.00000 0.00198 0.029170.00000 0.00000 0.00000

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0.00000 0.00094 0.000000.00000 0.00000 0.000000.00000 0.00127 0.000000.00000 0.00096 0.000000.00000 0.00217 0.000120.00000 0.00302 0.025320.00000 0.00000 0.000010.00000 0.00080 0.049600.00001 0.00157 0.039090.00000 0.00000 0.000000.00000 0.00118 0.000010.00000 0.00005 0.000040.00001 0.00290 0.000010.00000 0.00281 0.000000.00000 0.00179 0.000000.00000 0.00341 0.07522

NA 0.29902 0.68600NA 0.71309 0.99477NA 0.52828 0.59635NA 0.57306 0.54324NA 0.61101 0.60619NA 0.52670 0.99894NA 0.75505 0.89848NA 0.08071 0.93842NA 0.27336 0.58699NA 0.37554 0.71474NA 0.40645 0.53927NA 0.78544 0.64365

0.37390 0.16761 0.51879NA 0.34561 0.54068NA 0.17611 0.83539NA 0.07396 0.63106

C. spiroforme(DSM 1552)

D. longicatena(DSM 13814)

E. rectale(ATCC 33656)

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NA -2.11772 -1.70594NA 1.25875 1.00962NA -1.53016 -2.08816NA 1.26079 -3.18032NA -1.44527 -2.01661NA 1.45808 -1.00194NA -1.13564 -1.20448NA -2.57760 -1.11973NA -2.25027 1.78535NA -1.49447 1.78112NA -1.73955 2.00372NA -1.11431 2.16482Inf -1.88781 3.62518NA -1.49154 3.22106NA -3.25388 1.24232NA -2.68706 2.23953

C. spiroforme(DSM 1552)

D. longicatena(DSM 13814)

E. rectale(ATCC 33656)

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0.00000 0.00233 0.000890.00000 0.00307 0.007290.00000 0.00085 0.007230.00000 0.00659 0.000860.00000 0.00228 0.020590.00000 0.00577 0.000950.00000 0.00310 0.003770.00000 0.00522 0.000780.00000 0.00297 0.001660.00000 0.00244 0.002100.00000 0.00283 0.016780.00000 0.00645 0.006000.00000 0.00256 0.006370.00000 0.00960 0.007500.00000 0.00390 0.014390.00000 0.00494 0.014170.00000 0.01331 0.004560.00000 0.00429 0.003750.00000 0.00711 0.011020.00000 0.00153 0.018160.00000 0.00538 0.033080.00000 0.00848 0.014860.00000 0.00385 0.011020.00000 0.00794 0.009990.00000 0.00634 0.004810.00000 0.02514 0.016940.00000 0.01778 0.011480.00000 0.01081 0.014520.00000 0.01689 0.016660.00000 0.00440 0.019280.00000 0.03864 0.015120.00000 0.03117 0.012670.00000 0.03104 0.027750.00000 0.03330 0.004490.00000 0.03266 0.013000.00000 0.04855 0.01351

F. prausnitzii(M21-2)

P. distasonis(ATCC 8503)

R. obeum(ATCC 29174)

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0.00000 0.04778 0.031920.00000 0.05207 0.019890.00000 0.03335 0.015290.00000 0.02058 0.031310.00000 0.04797 0.028160.00000 0.02573 0.018250.00000 0.03083 0.018570.00000 0.03258 0.014600.00000 0.04276 0.018350.00000 0.05536 0.020340.00000 0.03448 0.026560.00000 0.05652 0.022810.00000 0.04453 0.020440.00000 0.04170 0.020980.00000 0.02582 0.018610.00000 0.03285 0.007710.00000 0.01234 0.008810.00000 0.02072 0.008350.00000 0.03971 0.013730.00000 0.04804 0.013510.00000 0.03981 0.010660.00000 0.04467 0.017220.00000 0.04281 0.013060.00000 0.02652 0.040590.00000 0.02479 0.012280.00000 0.02976 0.016200.00000 0.01251 0.005520.00000 0.02399 0.019150.00000 0.03101 0.013930.00000 0.04547 0.011530.00000 0.03265 0.019470.00000 0.03585 0.013830.00000 0.03821 0.018710.00000 0.02808 0.022260.00000 0.03699 0.008420.00000 0.03635 0.008100.00000 0.02191 0.008180.00000 0.02437 0.006400.00000 0.01767 0.022000.00000 0.04100 0.008590.00000 0.03534 0.017250.00000 0.03898 0.023270.00000 0.02988 0.014140.00000 0.02235 0.04257

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0.00000 0.04538 0.011310.00000 0.03635 0.024360.00000 0.04867 0.020970.00000 0.03839 0.013920.00000 0.02118 0.025760.00000 0.04991 0.008100.00000 0.04298 0.006000.00000 0.06113 0.011940.00000 0.03856 0.015640.00000 0.01702 0.014060.00000 0.04194 0.009140.00000 0.04942 0.008190.00000 0.03517 0.010610.00000 0.02719 0.012380.00000 0.05532 0.010830.00000 0.05510 0.012120.00000 0.03826 0.010720.00000 0.07902 0.010380.00000 0.03059 0.010580.00000 0.01837 0.015080.00000 0.05512 0.006440.00000 0.04933 0.009680.00000 0.03118 0.011380.00000 0.03607 0.015080.00000 0.04599 0.012140.00000 0.04292 0.015150.00000 0.04036 0.017080.00000 0.05581 0.016150.00000 0.05437 0.013620.00000 0.02315 0.016340.00000 0.04563 0.019970.00000 0.05400 0.011930.00000 0.06324 0.010940.00000 0.04692 0.011910.00000 0.03957 0.011890.00000 0.05176 0.013860.00000 0.05196 0.013880.00000 0.05440 0.010630.00000 0.04169 0.011320.00000 0.03909 0.013770.00000 0.07321 0.009710.00000 0.05306 0.008820.00000 0.03213 0.007450.00000 0.03164 0.05756

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0.00000 0.05238 0.012560.00000 0.06419 0.010570.00000 0.06535 0.013070.00000 0.05690 0.008320.00000 0.04631 0.010250.00000 0.03398 0.007210.00000 0.07598 0.023010.00000 0.05181 0.010930.00000 0.03728 0.010860.00000 0.04172 0.024310.00000 0.06387 0.022400.00000 0.06495 0.025290.00000 0.05886 0.028150.00000 0.05733 0.025070.00000 0.05698 0.020330.00000 0.02975 0.02723

NA 0.16074 0.02965NA 0.30406 0.59538NA 0.05951 0.09153NA 0.07838 0.06435NA 0.17029 0.04133NA 0.04318 0.86677NA 0.21648 0.37835NA 0.60339 0.00141NA 0.39302 0.01192NA 0.85027 0.00014NA 0.24178 0.01526NA 0.67125 0.00254NA 0.58053 0.00313NA 0.81484 0.00029NA 0.20230 0.97214NA 0.37634 0.00005

F. prausnitzii(M21-2)

P. distasonis(ATCC 8503)

R. obeum(ATCC 29174)

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NA -1.36850 -1.71191NA -1.15232 -1.16923NA -1.47380 -1.45987NA -1.29023 -1.29524NA -1.31020 -1.84396NA -1.38810 -1.05021NA -1.22433 -1.15381NA -1.10965 -1.99345NA 1.16214 -1.91460NA -1.05078 -1.88722NA 1.21020 -1.78963NA -1.07378 -1.41851NA 1.07214 -1.66746NA 1.02712 -1.75092NA 1.34770 -1.01899NA 1.14681 -2.24881

F. prausnitzii(M21-2)

P. distasonis(ATCC 8503)

R. obeum(ATCC 29174)

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0.00040 0.00000 0.000000.03691 0.00000 0.000000.08750 0.00000 0.000000.00017 0.00000 0.000000.04985 0.00000 0.000000.00302 0.00000 0.000000.01721 0.00000 0.000000.01325 0.00000 0.000000.01831 0.00000 0.000000.03057 0.00000 0.000000.04011 0.00000 0.000000.03182 0.00000 0.000000.02081 0.00000 0.000000.00340 0.00000 0.000000.03751 0.00000 0.000000.04790 0.00000 0.000000.03538 0.00000 0.000000.01345 0.00000 0.000000.01897 0.00000 0.000000.03097 0.00000 0.000000.03026 0.00000 0.000000.02238 0.00000 0.000000.02138 0.00000 0.000000.01275 0.00000 0.000000.01783 0.00000 0.000000.01250 0.00000 0.000000.02472 0.00000 0.000000.01219 0.00000 0.000000.01613 0.00000 0.000000.03985 0.00000 0.000000.01182 0.00000 0.000000.02321 0.00000 0.000000.02292 0.00000 0.000000.00956 0.00000 0.000000.01092 0.00000 0.000000.01986 0.00000 0.00000

R. torques(ATCC 27756)

B. animalis(CNCM I-2494)

L. delbrueckii(CNCM I-1632)

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0.02465 0.00000 0.000000.02271 0.00000 0.000000.01784 0.00000 0.000000.02019 0.00000 0.000000.00615 0.00000 0.000000.01312 0.00000 0.000000.01218 0.00000 0.000000.01071 0.00000 0.000000.01575 0.00000 0.000000.01031 0.00000 0.000000.00719 0.00000 0.000000.00965 0.00000 0.000000.01075 0.00000 0.000000.01080 0.00000 0.000000.00593 0.00000 0.000000.00371 0.00000 0.000000.00346 0.00003 0.000000.00739 0.00005 0.000000.00824 0.00006 0.000000.00678 0.00000 0.000000.00459 0.00000 0.000000.00780 0.00000 0.000000.00636 0.00000 0.000000.02061 0.00000 0.000000.00448 0.00000 0.000000.01021 0.00006 0.000000.00257 0.00000 0.000000.01010 0.00012 0.000000.00617 0.00000 0.000000.00547 0.00000 0.000000.00822 0.00000 0.000000.00889 0.00000 0.000000.00750 0.00000 0.000000.00866 0.00000 0.000000.00454 0.00000 0.000000.00596 0.00051 0.000000.00536 0.00000 0.000000.00560 0.00014 0.000000.01083 0.00050 0.000000.00847 0.00000 0.000000.00935 0.00008 0.000000.01130 0.00000 0.000000.01105 0.00000 0.000000.01660 0.00000 0.00000

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0.00812 0.00000 0.000000.01209 0.00229 0.000000.00799 0.00000 0.000070.00445 0.00000 0.000000.00973 0.00000 0.000000.00868 0.00000 0.000000.00221 0.00018 0.000000.00605 0.00003 0.000000.00512 0.00000 0.000000.00458 0.00000 0.000000.00330 0.00114 0.000000.00705 0.00082 0.000000.00701 0.00088 0.000000.00934 0.00062 0.000000.00543 0.00148 0.000000.00689 0.00004 0.000000.00619 0.00296 0.000000.00388 0.00128 0.000000.00714 0.00010 0.000000.00844 0.00090 0.000040.00765 0.00082 0.000000.02195 0.00110 0.000000.01812 0.00201 0.000000.01749 0.00084 0.000000.02268 0.00055 0.000000.01816 0.00131 0.000000.01292 0.00207 0.000000.01717 0.00212 0.000000.01645 0.00082 0.000000.01657 0.00202 0.000000.03645 0.00068 0.000000.00947 0.00159 0.000000.01244 0.00021 0.000000.01185 0.00098 0.000000.01048 0.00197 0.000000.01645 0.00130 0.000000.01550 0.00246 0.000000.01244 0.00030 0.000000.01063 0.00057 0.000000.01279 0.00193 0.000000.00713 0.00069 0.000000.01677 0.00225 0.000000.02482 0.00074 0.000000.03536 0.01110 0.00000

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0.01755 0.00167 0.000000.02755 0.00043 0.000000.01195 0.00055 0.000000.01214 0.00041 0.000000.01834 0.00109 0.000000.01736 0.00070 0.000000.00955 0.00180 0.000000.01147 0.00086 0.000000.01888 0.00080 0.000000.03543 0.00107 0.000000.01397 0.00202 0.000000.01683 0.00312 0.000000.01721 0.00132 0.000000.01597 0.00185 0.000000.01043 0.00116 0.000000.01235 0.00368 0.00000

0.017540.870700.057290.060700.032670.343780.407100.009960.029650.012640.099030.000500.279600.019590.139030.05113

R. torques(ATCC 27756)

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-2.01683-1.05548-1.72719-1.25682-1.792991.16569-1.14893-1.82781-1.80199-1.496801.517881.668781.657061.392731.754891.79392

R. torques(ATCC 27756)

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0.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.00000

L. delbrueckii(CNCM I-1519)

L. lactis(CNCM I-1631)

S. thermophilus(CNCM I-1630)

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0.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000040.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000070.00000 0.00000 0.000030.00000 0.00000 0.000040.00000 0.00000 0.000030.00000 0.00000 0.000000.00000 0.00004 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00003 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00003 0.000000.00000 0.00004 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000030.00000 0.00000 0.000000.00000 0.00004 0.000000.00000 0.00012 0.00000

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0.00000 0.00000 0.000030.00000 0.00007 0.000040.00010 0.00005 0.000150.00000 0.00003 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00004 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00005 0.000000.00000 0.00000 0.000000.00000 0.00005 0.000000.00000 0.00003 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00011 0.000000.00000 0.00004 0.000000.00020 0.00000 0.000070.00004 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00007 0.000000.00000 0.00004 0.000000.00000 0.00000 0.000000.00000 0.00005 0.000000.00000 0.00005 0.000000.00000 0.00006 0.000000.00000 0.00007 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00005 0.00000

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0.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00000 0.000000.00000 0.00006 0.000000.00000 0.00009 0.000000.00000 0.00000 0.000010.00000 0.00001 0.000000.00000 0.00006 0.000010.00000 0.00001 0.000000.00000 0.00000 0.000000.00000 0.00001 0.000020.00000 0.00006 0.000000.00000 0.00001 0.000010.00000 0.00010 0.000010.00000 0.00015 0.00002

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Table S6. INSeq analysis.

A. INSeq analysis sequencing statistics.

INSeq run statistics RunID Total Reads Barcode ReadsAGS97 15253513 14770639AGS98 13033340 12415448AGS99 17241863 16486514

AGS100 16569193 15534518AGS107 25886560 24821328AGS108 27417746 26589650

INSeq sample statistics SampleID RunID BarcodeIN1 AGS97 GCTAIN2 AGS97 GGAA1.4 AGS97 GGGG2.4 AGS97 GTAC3.4 AGS97 GTCA4.4 AGS97 TATA5.4 AGS97 TCAG6.4 AGS97 TCGA7.4 AGS97 TTAA8.4 AGS97 AAAA9.4 AGS98 GAAG

10.4 AGS98 CCTT1.5 AGS98 AACC2.5 AGS98 TTGG3.5 AGS98 TTTT4.5 AGS98 ACCA5.5 AGS98 ACGT6.5 AGS98 AGGA7.5 AGS98 AGTC8.5 AGS98 ATCG9.5 AGS99 CATG

10.5 AGS99 CCAA1.6 AGS99 CCCC2.6 AGS99 CGAT3.6 AGS99 GCTA4.6 AGS99 GGAA5.6 AGS99 GGGG6.6 AGS99 GTAC7.6 AGS99 GTCA8.6 AGS99 TATA

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9.6 AGS99 TCAG10.6 AGS100 TCGA1.8 AGS100 TTAA2.8 AGS100 AAAA3.8 AGS100 GAAG4.8 AGS100 CCTT5.8 AGS100 AACC6.8 AGS100 TTGG7.8 AGS100 TTTT8.8 AGS100 ACCA9.8 AGS100 ACGT

10.8 AGS100 AGGA6.6b AGS107 GTAC1.6b AGS108 CCCC

10.6b AGS108 TCGA

GeneID Input d14 d14/inputBT_0001 14 1 0.05BT_0002 19 69 3.62BT_0003 296 351 1.18BT_0004 0 0 0.48BT_0005 4 2 0.39BT_0006 30 0 0.00BT_0007 0 0 N/DBT_0008 137 101 0.74BT_0009 22 11 0.53BT_0010 145 177 1.22BT_0011 7 6 0.83BT_0012 13 1 0.09BT_0013 0 0 N/DBT_0014 10 5 0.54BT_0015 3 2 0.61BT_0016 1 0 0.56BT_0017 71 50 0.70BT_0018 0 0 0.79BT_0019 24 9 0.38BT_0020 0 0 N/DBT_0021 1 0 0.36BT_0022 10 7 0.71BT_0023 41 1 0.02BT_0024 5 23 4.47

B. Genes required by B. thetaiotaomicron for survival in the intestines of mice harboring the 15-member model human gut microbiota.

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BT_0025 7 1 0.16BT_0026 40 105 2.59BT_0027 91 96 1.06BT_0028 9 0 0.03BT_0029 142 157 1.11BT_0030 563 623 1.10BT_0031 71 379 5.34BT_0032 554 335 0.60BT_0033 71 104 1.46BT_0034 575 483 0.84BT_0035 6 0 0.03BT_0036 169 56 0.33BT_0037 30 100 3.30BT_0038 6 31 5.62BT_0039 9 0 0.04BT_0040 31 50 1.63BT_0041 75 47 0.62BT_0042 25 2 0.09BT_0043 26 12 0.44BT_0044 0 0 0.68BT_0045 1 0 0.34BT_0046 47 47 1.01BT_0047 34 26 0.78BT_0048 1 0 0.32BT_0049 0 0 N/DBT_0050 14 5 0.35BT_0051 33 1 0.02BT_0052 128 981 7.66BT_0053 11 1 0.08BT_0054 29 77 2.66BT_0055 19 39 2.11BT_0056 0 0 N/DBT_0057 0 0 0.26BT_0058 2 2 0.92BT_0059 0 0 N/DBT_0060 6 0 0.01BT_0061 0 0 0.68BT_0062 0 0 N/DBT_0063 0 0 N/DBT_0064 1 0 0.33BT_0065 2 3 1.37BT_0066 79 19 0.24BT_0067 16 9 0.57BT_0068 0 0 N/D

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BT_0069 7 1 0.20BT_0070 55 67 1.21BT_0071 1 0 0.53BT_0072 4 13 3.45BT_0073 51 84 1.65BT_0074 16 17 1.07BT_0075 0 1 N/DBT_0076 19 5 0.28BT_0077 4 11 3.11BT_0078 21 5 0.26BT_0079 0 0 N/DBT_0080 2 0 0.04BT_0081 0 0 N/DBT_0082 139 162 1.16BT_0083 349 942 2.70BT_0084 0 0 N/DBT_0085 0 0 N/DBT_0086 1 0 0.14BT_0087 36 0 0.01BT_0088 0 0 0.45BT_0089 7 9 1.22BT_0090 95 49 0.52BT_0091 1 0 0.24BT_0092 0 0 N/DBT_0093 6 2 0.28BT_0094 1 0 0.07BT_0095 0 0 N/DBT_0096 1 0 0.25BT_0097 5 2 0.42BT_0098 0 1 N/DBT_0099 13 8 0.59BT_0100 0 0 N/DBT_0101 57 17 0.30BT_0102 29 51 1.75BT_0103 5 0 0.10BT_0104 0 0 N/DBT_0105 2 0 0.07BT_0106 0 0 N/DBT_0107 0 0 N/DBT_0108 59 4 0.06BT_0109 10 5 0.54BT_0110 18 17 0.96BT_0111 16 12 0.70BT_0112 0 0 0.00

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BT_0113 0 0 N/DBT_0114 30 51 1.67BT_0115 0 0 N/DBT_0116 14 23 1.66BT_0117 4 1 0.13BT_0118 1 2 2.39BT_0119 0 0 0.61BT_0120 0 0 N/DBT_0121 4 3 0.74BT_0122 303 1855 6.11BT_0123 1 0 0.15BT_0124 4 0 0.09BT_0125 18 7 0.39BT_0126 6 4 0.58BT_0127 72 45 0.62BT_0128 959 1619 1.69BT_0129 2 1 0.43BT_0130 0 0 N/DBT_0131 0 0 N/DBT_0132 56 12 0.22BT_0133 0 0 N/DBT_0134 2 0 0.22BT_0135 30 143 4.77BT_0136 14 21 1.49BT_0137 1 1 0.89BT_0138 14 14 0.97BT_0139 2 7 4.41BT_0140 35 41 1.18BT_0141 4 2 0.66BT_0142 21 15 0.72BT_0143 13 15 1.19BT_0144 0 0 N/DBT_0145 0 1 1.20BT_0146 169 7 0.04BT_0147 582 443 0.76BT_0148 49 41 0.84BT_0149 420 540 1.29BT_0150 10 66 6.73BT_0151 77 23 0.29BT_0152 238 370 1.55BT_0153 145 175 1.21BT_0154 1025 680 0.66BT_0155 27 3 0.11BT_0156 3 1 0.25

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BT_0157 41 55 1.35BT_0158 59 17 0.29BT_0159 103 118 1.15BT_0160 9 42 4.60BT_0161 15 7 0.44BT_0162 1 0 0.08BT_0163 6 7 1.18BT_0164 187 303 1.62BT_0165 33 59 1.82BT_0166 59 107 1.82BT_0167 449 620 1.38BT_0168 14 10 0.76BT_0169 532 676 1.27BT_0170 2 2 1.17BT_0171 37 61 1.68BT_0172 7 14 1.92BT_0173 776 18 0.02BT_0174 338 12 0.04BT_0175 0 0 0.00BT_0176 280 279 1.00BT_0177 1416 11 0.01BT_0178 31 1 0.02BT_0179 86 1 0.01BT_0180 359 32 0.09BT_0181 0 0 N/DBT_0182 102 176 1.73BT_0183 72 125 1.73BT_0184 141 77 0.55BT_0185 68 0 0.00BT_0186 506 1 0.00BT_0187 15 4 0.25BT_0188 20 47 2.33BT_0189 17 8 0.49BT_0190 25 10 0.39BT_0191 60 49 0.81BT_0192 1 3 3.44BT_0193 17 0 0.01BT_0194 1 1 1.03BT_0195 0 0 N/DBT_0196 9 13 1.42BT_0197 6 4 0.67BT_0198 18 10 0.54BT_0199 90 122 1.36BT_0200 193 122 0.63

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BT_0201 214 35 0.16BT_0202 214 45 0.21BT_0203 118 21 0.18BT_0204 0 0 N/DBT_0205 0 1 N/DBT_0206 29 6 0.20BT_0207 7 0 0.05BT_0208 26 9 0.33BT_0209 5 7 1.36BT_0210 64 97 1.51BT_0211 70 16 0.23BT_0212 12 1 0.11BT_0213 0 0 1.12BT_0214 12 17 1.38BT_0215 2100 1067 0.51BT_0216 1498 712 0.48BT_0217 209 175 0.84BT_0218 3 17 5.97BT_0219 0 31 N/DBT_0220 0 0 0.00BT_0221 991 702 0.71BT_0222 73 0 0.00BT_0223 8 15 1.92BT_0224 21 29 1.38BT_0225 123 278 2.26BT_0226 93 248 2.68BT_0227 937 1312 1.40BT_0228 3 0 0.14BT_0229 15 1 0.06BT_0230 0 1 N/DBT_0231 1 0 0.15BT_0232 0 0 N/DBT_0233 0 0 0.00BT_0234 0 1 1.58BT_0235 10 35 3.46BT_0236 1650 2461 1.49BT_0237 1667 1004 0.60BT_0238 212 14 0.07BT_0239 765 433 0.57BT_0240 77 166 2.17BT_0241 1111 405 0.36BT_0242 1420 3264 2.30BT_0243 31 2 0.05BT_0244 63 75 1.20

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BT_0245 5 10 1.91BT_0246 0 0 N/DBT_0247 53 0 0.00BT_0248 3 1 0.25BT_0249 72 2 0.03BT_0250 154 0 0.00BT_0251 0 0 N/DBT_0252 144 274 1.90BT_0253 3 19 6.77BT_0254 28 92 3.34BT_0255 49 68 1.38BT_0256 228 307 1.35BT_0257 32 37 1.16BT_0258 2204 32 0.01BT_0259 97 169 1.74BT_0260 803 300 0.37BT_0261 138 14 0.10BT_0262 8 0 0.02BT_0263 66 1 0.02BT_0264 19 48 2.56BT_0265 27 8 0.29BT_0266 24 1 0.02BT_0267 90 11 0.12BT_0268 54 14 0.26BT_0269 14 89 6.45BT_0270 3 2 0.65BT_0271 21 20 0.96BT_0272 62 30 0.49BT_0273 27 3 0.13BT_0274 31 50 1.59BT_0275 4 1 0.22BT_0276 25 1 0.05BT_0277 10 3 0.30BT_0278 55 55 1.00BT_0279 2 1 0.41BT_0280 0 0 N/DBT_0281 52 66 1.26BT_0282 33 7 0.20BT_0283 0 0 N/DBT_0284 2 0 0.15BT_0285 103 24 0.24BT_0286 0 0 N/DBT_0287 0 0 0.30BT_0288 2 12 7.17

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BT_0289 24 9 0.38BT_0290 53 33 0.62BT_0291 20 1 0.05BT_0292 11 7 0.64BT_0293 14 16 1.11BT_0294 102 102 1.00BT_0295 6 17 2.92BT_0296 57 26 0.45BT_0297 0 1 N/DBT_0298 0 0 N/DBT_0299 102 350 3.43BT_0300 69 27 0.39BT_0301 49 7 0.13BT_0302 18 14 0.79BT_0303 7 25 3.65BT_0304 14 60 4.20BT_0305 125 107 0.85BT_0306 13 6 0.48BT_0307 0 0 N/DBT_0308 21 84 4.04BT_0309 11 31 2.77BT_0310 0 0 0.18BT_0311 13 2 0.16BT_0312 11 6 0.54BT_0313 52 60 1.16BT_0314 94 68 0.72BT_0315 9936 641 0.06BT_0316 2502 1632 0.65BT_0317 18 14 0.76BT_0318 31 8 0.25BT_0319 0 0 N/DBT_0320 140 124 0.89BT_0321 108 61 0.56BT_0322 256 29 0.11BT_0323 17 1 0.04BT_0324 613 0 0.00BT_0325 916 1 0.00BT_0326 0 0 N/DBT_0327 7 21 2.92BT_0328 0 0 N/DBT_0329 20 0 0.01BT_0330 21 0 0.00BT_0331 36 0 0.01BT_0332 5 0 0.03

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BT_0333 13 0 0.01BT_0334 12 0 0.00BT_0335 1 0 0.59BT_0336 4 1 0.13BT_0337 0 0 N/DBT_0338 25 51 2.02BT_0339 18 10 0.57BT_0340 13 3 0.27BT_0341 12 10 0.88BT_0342 30 126 4.23BT_0343 0 0 N/DBT_0344 21 35 1.67BT_0345 8 14 1.74BT_0346 94 5 0.05BT_0347 372 0 0.00BT_0348 9 1 0.08BT_0349 0 0 N/DBT_0350 180 0 0.00BT_0351 31 0 0.01BT_0352 1 0 0.14BT_0353 8 0 0.06BT_0354 249 0 0.00BT_0355 1568 3 0.00BT_0356 1266 7 0.01BT_0357 0 0 N/DBT_0358 0 0 N/DBT_0359 0 0 N/DBT_0360 11 9 0.87BT_0361 4 1 0.30BT_0362 35 16 0.47BT_0363 41 2 0.05BT_0364 22 1 0.03BT_0365 7 17 2.31BT_0366 12 9 0.69BT_0367 24 1136 47.99BT_0368 44 48 1.07BT_0369 0 0 N/DBT_0370 4391 8 0.00BT_0371 9 0 0.04BT_0372 3 9 3.13BT_0373 1290 0 0.00BT_0374 0 1 N/DBT_0375 0 0 N/DBT_0376 34 174 5.19

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BT_0377 2 1 0.72BT_0378 9 2 0.19BT_0379 92 17 0.19BT_0380 211 84 0.40BT_0381 207 99 0.48BT_0382 49 124 2.51BT_0383 62 45 0.72BT_0384 166 181 1.09BT_0385 123 81 0.66BT_0386 75 18 0.24BT_0387 27 12 0.45BT_0388 50 27 0.54BT_0389 171 161 0.94BT_0390 80 38 0.48BT_0391 70 23 0.32BT_0392 78 44 0.56BT_0393 24 86 3.62BT_0394 5 1 0.19BT_0395 19 4 0.23BT_0396 56 32 0.56BT_0397 0 0 N/DBT_0398 0 0 N/DBT_0399 79 90 1.13BT_0400 7 2 0.23BT_0401 0 0 N/DBT_0402 0 0 N/DBT_0403 0 0 N/DBT_0404 5 0 0.08BT_0405 0 0 N/DBT_0406 67 23 0.35BT_0407 553 179 0.32BT_0408 65 63 0.96BT_0409 345 211 0.61BT_0410 1125 991 0.88BT_0411 358 424 1.18BT_0412 258 166 0.64BT_0413 101 16 0.16BT_0414 480 201 0.42BT_0415 1036 578 0.56BT_0416 576 822 1.43BT_0417 648 769 1.19BT_0418 3772 70 0.02BT_0419 0 0 0.00BT_0420 4 0 0.00

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BT_0421 1154 38 0.03BT_0422 0 0 N/DBT_0423 0 0 N/DBT_0424 0 0 N/DBT_0425 0 0 N/DBT_0426 14 29 2.06BT_0427 2 4 2.20BT_0428 469 783 1.67BT_0429 327 445 1.36BT_0430 638 970 1.52BT_0431 24 5 0.19BT_0432 7 17 2.47BT_0433 1238 134 0.11BT_0434 12 1 0.11BT_0435 1 0 0.44BT_0436 1 1 0.75BT_0437 1 0 0.14BT_0438 86 41 0.47BT_0439 48 9 0.18BT_0440 0 1 1.29BT_0441 5 4 0.69BT_0442 13 57 4.30BT_0443 0 0 N/DBT_0444 1 1 0.88BT_0445 0 1 N/DBT_0446 0 3 N/DBT_0447 10 17 1.70BT_0448 24 48 2.02BT_0449 43 131 3.04BT_0450 4 1 0.21BT_0451 0 1 N/DBT_0452 24 35 1.45BT_0453 1 2 3.07BT_0454 0 0 N/DBT_0455 360 412 1.14BT_0456 279 578 2.07BT_0457 52 106 2.04BT_0458 275 259 0.94BT_0459 1096 662 0.60BT_0460 9 15 1.75BT_0461 37 114 3.05BT_0462 36 27 0.74BT_0463 0 0 N/DBT_0464 1 0 0.15

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BT_0465 6 13 1.95BT_0466 6 2 0.44BT_0467 38 7 0.19BT_0468 54 34 0.62BT_0469 141 23 0.17BT_0470 21 15 0.69BT_0471 12 12 0.98BT_0472 11 1 0.08BT_0473 8 7 0.85BT_0474 1 0 0.40BT_0475 0 0 N/DBT_0476 4 0 0.09BT_0477 17 3 0.16BT_0478 0 2 5.61BT_0479 2 0 0.04BT_0480 7 10 1.30BT_0481 0 0 N/DBT_0482 28 28 1.01BT_0483 122 39 0.32BT_0484 0 0 0.81BT_0485 0 0 N/DBT_0486 17 8 0.49BT_0487 82 22 0.27BT_0488 269 6 0.02BT_0489 189 3 0.01BT_0490 62 36 0.57BT_0491 0 0 0.18BT_0492 13 12 0.89BT_0493 6 0 0.01BT_0494 56 7 0.13BT_0495 23 32 1.41BT_0496 12 8 0.69BT_0497 0 0 0.26BT_0498 23 16 0.69BT_0499 0 0 N/DBT_0500 11 18 1.62BT_0501 239 487 2.04BT_0502 230 283 1.23BT_0503 64 234 3.64BT_0504 1030 1677 1.63BT_0505 0 1 N/DBT_0506 3 45 13.62BT_0507 0 0 N/DBT_0508 31 9 0.28

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BT_0509 0 1 N/DBT_0510 3 5 1.77BT_0511 0 24 56.51BT_0512 1 0 0.37BT_0513 0 0 N/DBT_0514 4 4 1.10BT_0515 10 1 0.11BT_0516 0 0 0.00BT_0517 0 1 1.22BT_0518 474 457 0.96BT_0519 33 48 1.44BT_0520 4 2 0.55BT_0521 0 0 1.08BT_0522 67 22 0.33BT_0523 9 2 0.20BT_0524 195 237 1.21BT_0525 477 941 1.97BT_0526 5 1 0.26BT_0527 148 1 0.01BT_0528 14 1 0.04BT_0529 10 1 0.07BT_0530 214 3 0.01BT_0531 6 0 0.05BT_0532 102 5 0.05BT_0533 45 3 0.06BT_0534 8 31 3.91BT_0535 164 272 1.66BT_0536 72 53 0.74BT_0537 46 93 2.02BT_0538 1 0 0.00BT_0539 70 207 2.96BT_0540 0 0 N/DBT_0541 42 48 1.12BT_0542 202 152 0.75BT_0543 2 1 0.37BT_0544 9 8 0.93BT_0545 0 0 N/DBT_0546 0 0 N/DBT_0547 0 0 N/DBT_0548 6 0 0.08BT_0549 0 8 18.06BT_0550 296 231 0.78BT_0551 3 3 0.89BT_0552 0 0 N/D

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BT_0553 135 5 0.03BT_0554 845 1 0.00BT_0555 989 0 0.00BT_0556 478 0 0.00BT_0557 1284 1 0.00BT_0558 307 284 0.92BT_0559 5 29 6.31BT_0560 0 1 N/DBT_0561 1 28 37.00BT_0562 11 1 0.14BT_0563 25 4 0.15BT_0564 51 78 1.52BT_0565 12 18 1.49BT_0566 15 3 0.23BT_0567 10 17 1.77BT_0568 0 3 6.86BT_0569 147 318 2.16BT_0570 140 7 0.05BT_0571 740 721 0.97BT_0572 609 552 0.91BT_0573 6 0 0.04BT_0574 2 0 0.00BT_0575 2 0 0.00BT_0576 16 11 0.68BT_0577 1 1 0.81BT_0578 370 108 0.29BT_0579 35 78 2.24BT_0580 2679 1171 0.44BT_0581 2 0 0.00BT_0582 446 464 1.04BT_0583 26 39 1.47BT_0584 1 2 2.92BT_0585 9 11 1.30BT_0586 231 350 1.52BT_0587 942 1027 1.09BT_0588 164 75 0.46BT_0589 0 1 N/DBT_0590 0 1 N/DBT_0591 349 189 0.54BT_0592 0 0 0.00BT_0593 0 0 N/DBT_0594 0 0 N/DBT_0595 1 0 0.10BT_0596 810 1127 1.39

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BT_0597 344 428 1.24BT_0598 198 398 2.01BT_0599 745 365 0.49BT_0600 600 213 0.35BT_0601 1274 646 0.51BT_0602 1324 789 0.60BT_0603 479 231 0.48BT_0604 564 173 0.31BT_0605 426 245 0.58BT_0606 84 13 0.15BT_0607 83 44 0.53BT_0608 250 142 0.57BT_0609 154 63 0.41BT_0610 376 97 0.26BT_0611 107 19 0.18BT_0612 292 202 0.69BT_0613 178 33 0.18BT_0614 172 126 0.73BT_0615 4 15 3.42BT_0616 28 1 0.03BT_0617 359 3 0.01BT_0618 593 4 0.01BT_0619 1009 4 0.00BT_0620 502 2 0.00BT_0621 254 1 0.00BT_0622 50 0 0.00BT_0623 2657 1 0.00BT_0624 1 1 1.15BT_0625 0 0 N/DBT_0626 1 1 0.70BT_0627 231 0 0.00BT_0628 557 1548 2.78BT_0629 27 29 1.07BT_0630 48 38 0.79BT_0631 151 184 1.22BT_0632 1192 359 0.30BT_0633 155 292 1.89BT_0634 3 21 6.31BT_0635 798 551 0.69BT_0636 9 12 1.31BT_0637 27 65 2.35BT_0638 110 190 1.73BT_0639 8 2 0.21BT_0640 13 11 0.79

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BT_0641 641 645 1.01BT_0642 513 978 1.91BT_0643 513 699 1.36BT_0644 4109 5244 1.28BT_0645 1418 1405 0.99BT_0646 1774 2630 1.48BT_0647 62 142 2.31BT_0648 16 1 0.04BT_0649 5 3 0.64BT_0650 21 2 0.07BT_0651 43 113 2.64BT_0652 14 3 0.19BT_0653 0 0 N/DBT_0654 16 23 1.49BT_0655 590 92 0.16BT_0656 14 9 0.64BT_0657 100 8 0.08BT_0658 86 83 0.96BT_0659 32 28 0.86BT_0660 103 155 1.50BT_0661 7 1 0.14BT_0662 6 2 0.31BT_0663 1 0 0.13BT_0664 2 0 0.14BT_0665 11 0 0.02BT_0666 30 89 3.00BT_0667 147 185 1.26BT_0668 16 18 1.09BT_0669 12 15 1.18BT_0670 137 101 0.74BT_0671 1 1 0.83BT_0672 14 2 0.14BT_0673 0 1 N/DBT_0674 40 118 2.96BT_0675 37 66 1.77BT_0676 22 51 2.34BT_0677 0 0 N/DBT_0678 0 3 6.84BT_0679 13 2 0.14BT_0680 2 5 3.02BT_0681 9 1 0.06BT_0682 2 12 6.02BT_0683 18 5 0.27BT_0684 191 301 1.58

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BT_0685 105 147 1.41BT_0686 7 20 2.84BT_0687 118 189 1.60BT_0688 0 0 N/DBT_0689 17 84 5.02BT_0690 36 34 0.94BT_0691 42 6 0.14BT_0692 16 3 0.16BT_0693 815 1129 1.39BT_0694 146 124 0.85BT_0695 24 16 0.67BT_0696 4 15 4.15BT_0697 35 44 1.25BT_0698 1 0 0.56BT_0699 453 402 0.89BT_0700 141 48 0.34BT_0701 1730 1032 0.60BT_0702 62 85 1.36BT_0703 42 25 0.59BT_0704 71 46 0.65BT_0705 32 79 2.50BT_0706 0 0 N/DBT_0707 0 1 1.61BT_0708 0 0 N/DBT_0709 6 7 1.23BT_0710 0 0 N/DBT_0711 145 100 0.69BT_0712 13 2 0.16BT_0713 14 33 2.30BT_0714 69 25 0.36BT_0715 29 8 0.26BT_0716 30 28 0.93BT_0717 57 56 0.99BT_0718 258 117 0.45BT_0719 10 0 0.00BT_0720 106 104 0.98BT_0721 39 85 2.18BT_0722 267 639 2.40BT_0723 18 37 2.01BT_0724 108 69 0.64BT_0725 5 3 0.61BT_0726 0 0 N/DBT_0727 3 12 3.75BT_0728 13 0 0.00

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BT_0729 10 7 0.70BT_0730 52 58 1.10BT_0731 13 55 4.17BT_0732 5 6 1.11BT_0733 13 7 0.57BT_0734 3 5 1.52BT_0735 0 0 N/DBT_0736 32 115 3.60BT_0737 428 474 1.11BT_0738 1297 177 0.14BT_0739 114 76 0.67BT_0740 91 168 1.84BT_0741 451 0 0.00BT_0742 1014 0 0.00BT_0743 1 1 0.66BT_0744 1 0 0.00BT_0745 1 1 0.68BT_0746 185 297 1.61BT_0747 662 45 0.07BT_0748 0 0 N/DBT_0749 117 103 0.88BT_0750 69 14 0.20BT_0751 158 113 0.71BT_0752 20 2 0.12BT_0753 62 112 1.81BT_0754 25 5 0.21BT_0755 2 11 5.04BT_0756 98 3 0.03BT_0757 154 21 0.14BT_0758 0 0 N/DBT_0759 0 0 N/DBT_0760 105 97 0.93BT_0761 58 55 0.95BT_0762 134 113 0.84BT_0763 16 1 0.04BT_0764 7 14 2.03BT_0765 38 15 0.38BT_0766 1521 1141 0.75BT_0767 4 37 9.27BT_0768 0 0 N/DBT_0769 954 1 0.00BT_0770 2022 0 0.00BT_0771 5060 0 0.00BT_0772 12 25 2.00

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BT_0773 334 6 0.02BT_0774 72 1 0.01BT_0775 15 5 0.35BT_0776 39 163 4.21BT_0777 62 22 0.36BT_0778 16 12 0.76BT_0779 0 3 7.75BT_0780 2 4 1.71BT_0781 12 32 2.59BT_0782 3 0 0.00BT_0783 0 0 N/DBT_0784 242 215 0.89BT_0785 1555 1666 1.07BT_0786 25 28 1.10BT_0787 5 0 0.02BT_0788 12 4 0.32BT_0789 0 2 5.14BT_0790 4 16 3.58BT_0791 0 0 N/DBT_0792 4 5 1.12BT_0793 12 20 1.71BT_0794 70 1 0.02BT_0795 0 0 0.31BT_0796 25 15 0.59BT_0797 8 9 1.18BT_0798 0 0 N/DBT_0799 0 0 N/DBT_0800 25 0 0.02BT_0801 9 25 2.68BT_0802 6 1 0.10BT_0803 2 0 0.06BT_0804 11 30 2.65BT_0805 2 3 1.05BT_0806 2 1 0.80BT_0807 1 0 0.00BT_0808 0 0 N/DBT_0809 48 1 0.03BT_0810 5 0 0.02BT_0811 150 247 1.64BT_0812 135 102 0.76BT_0813 14 15 1.11BT_0814 100 320 3.21BT_0815 1114 923 0.83BT_0816 3 2 0.61

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BT_0817 316 359 1.14BT_0818 36 3 0.07BT_0819 20 50 2.51BT_0820 84 170 2.02BT_0821 356 821 2.31BT_0822 450 803 1.78BT_0823 69 16 0.22BT_0824 37 3 0.09BT_0825 13 12 0.96BT_0826 154 93 0.60BT_0827 301 34 0.11BT_0828 84 153 1.83BT_0829 788 1004 1.27BT_0830 311 332 1.07BT_0831 1709 4372 2.56BT_0832 274 462 1.69BT_0833 218 314 1.44BT_0834 0 0 0.53BT_0835 0 0 N/DBT_0836 0 0 N/DBT_0837 1 1 0.58BT_0838 2 10 3.97BT_0839 13 4 0.28BT_0840 58 99 1.71BT_0841 109 249 2.29BT_0842 48 36 0.76BT_0843 27 26 0.96BT_0844 18 27 1.49BT_0845 49 44 0.91BT_0846 11 26 2.30BT_0847 67 189 2.81BT_0848 325 377 1.16BT_0849 0 0 N/DBT_0850 1 0 0.00BT_0851 21 7 0.34BT_0852 5 1 0.11BT_0853 41 11 0.27BT_0854 31 68 2.21BT_0855 0 1 N/DBT_0856 9 1 0.06BT_0857 12 27 2.18BT_0858 1 0 0.08BT_0859 9 4 0.45BT_0860 2 6 3.07

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BT_0861 7 2 0.22BT_0862 76 119 1.58BT_0863 4 1 0.21BT_0864 76 18 0.24BT_0865 33 43 1.31BT_0866 28 42 1.47BT_0867 18 10 0.57BT_0868 31 47 1.52BT_0869 396 444 1.12BT_0870 1204 15 0.01BT_0871 10 0 0.01BT_0872 0 1 1.27BT_0873 1287 3235 2.51BT_0874 13 34 2.64BT_0875 105 144 1.38BT_0876 246 51 0.21BT_0877 86 90 1.05BT_0878 3 31 11.44BT_0879 23 11 0.47BT_0880 2 0 0.00BT_0881 8 11 1.31BT_0882 0 1 1.91BT_0883 0 0 N/DBT_0884 0 0 0.36BT_0885 5 0 0.09BT_0886 4 6 1.37BT_0887 1 0 0.25BT_0888 1 1 0.82BT_0889 1 1 0.70BT_0890 1 0 0.20BT_0891 566 0 0.00BT_0892 156 0 0.00BT_0893 19 6 0.34BT_0894 0 1 2.58BT_0895 2 0 0.17BT_0896 71 72 1.02BT_0897 2018 2091 1.04BT_0898 304 46 0.15BT_0899 1 1 0.68BT_0900 3407 20 0.01BT_0901 756 602 0.80BT_0902 611 174 0.28BT_0903 546 0 0.00BT_0904 612 1 0.00

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BT_0905 124 0 0.00BT_0906 368 0 0.00BT_0907 766 0 0.00BT_0908 306 1 0.00BT_0909 433 0 0.00BT_0910 797 1 0.00BT_0911 890 726 0.82BT_0912 490 268 0.55BT_0913 1286 1741 1.35BT_0914 0 1 1.26BT_0915 0 0 N/DBT_0916 0 0 N/DBT_0917 9 3 0.34BT_0918 0 0 N/DBT_0919 0 0 N/DBT_0920 0 0 N/DBT_0921 30 672 22.27BT_0922 0 1 N/DBT_0923 19 6 0.33BT_0924 31 4 0.14BT_0925 3 1 0.33BT_0926 20 37 1.88BT_0927 1 1 0.73BT_0928 0 0 N/DBT_0929 1 1 0.76BT_0930 4 0 0.02BT_0931 82 98 1.18BT_0932 21 2 0.12BT_0933 0 0 0.00BT_0934 2 1 0.50BT_0935 0 0 N/DBT_0936 2 4 2.24BT_0937 4 15 3.47BT_0938 351 1982 5.64BT_0939 3 19 5.93BT_0940 135 19 0.14BT_0941 13 50 3.76BT_0942 8 1 0.16BT_0943 19 17 0.92BT_0944 20 46 2.31BT_0945 36 64 1.80BT_0946 21 21 0.99BT_0947 1 0 0.26BT_0948 1 1 0.69

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BT_0949 0 0 N/DBT_0950 10 59 5.84BT_0951 67 17 0.26BT_0952 14 6 0.39BT_0953 10 7 0.72BT_0954 2 1 0.24BT_0955 17 47 2.85BT_0956 21 69 3.28BT_0957 49 22 0.44BT_0958 84 50 0.60BT_0959 1 0 0.14BT_0960 9 1 0.13BT_0961 0 0 N/DBT_0962 47 31 0.66BT_0963 9 0 0.01BT_0964 6 2 0.25BT_0965 54 89 1.65BT_0966 72 69 0.95BT_0967 0 0 N/DBT_0968 80 30 0.37BT_0969 79 177 2.24BT_0970 396 409 1.03BT_0971 130 256 1.97BT_0972 0 0 N/DBT_0973 399 269 0.67BT_0974 232 7 0.03BT_0975 427 14 0.03BT_0976 2 0 0.09BT_0977 5 1 0.14BT_0978 7 0 0.05BT_0979 22 31 1.40BT_0980 0 0 N/DBT_0981 105 793 7.56BT_0982 5 1 0.23BT_0983 88 27 0.31BT_0984 0 1 N/DBT_0985 8 5 0.59BT_0986 8 4 0.45BT_0987 76 37 0.49BT_0988 8 11 1.38BT_0989 6 0 0.01BT_0990 14 9 0.63BT_0991 0 0 N/DBT_0992 9 2 0.23

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BT_0993 6 6 1.04BT_0994 3 1 0.30BT_0995 0 0 0.18BT_0996 45 69 1.53BT_0997 17 1 0.08BT_0998 150 323 2.15BT_0999 0 0 N/DBT_1000 19 4 0.19BT_1001 17 15 0.87BT_1002 14 2 0.16BT_1003 67 29 0.43BT_1004 0 0 N/DBT_1005 0 0 N/DBT_1006 56 60 1.08BT_1007 725 777 1.07BT_1008 3 4 1.46BT_1009 3 3 1.06BT_1010 32 4 0.12BT_1011 0 0 N/DBT_1012 11 2 0.14BT_1013 24 1 0.04BT_1014 30 11 0.36BT_1015 200 216 1.08BT_1016 49 33 0.68BT_1017 21 11 0.52BT_1018 7 1 0.07BT_1019 37 9 0.23BT_1020 101 2 0.02BT_1021 0 1 N/DBT_1022 0 0 0.23BT_1023 23 1 0.04BT_1024 29 31 1.06BT_1025 37 32 0.87BT_1026 6 0 0.02BT_1027 0 0 N/DBT_1028 7 106 14.63BT_1029 24 7 0.27BT_1030 8 3 0.38BT_1031 13 2 0.12BT_1032 1138 1086 0.95BT_1033 441 221 0.50BT_1034 60 60 1.01BT_1035 64 48 0.75BT_1036 1331 2747 2.06

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BT_1037 266 673 2.53BT_1038 100 397 3.95BT_1039 13 6 0.44BT_1040 73 63 0.86BT_1041 133 98 0.74BT_1042 182 213 1.18BT_1043 3 15 5.19BT_1044 102 261 2.55BT_1045 602 1069 1.78BT_1046 23 27 1.17BT_1047 0 1 1.30BT_1048 4 8 1.78BT_1049 6 2 0.44BT_1050 76 7 0.09BT_1051 20 20 1.00BT_1052 928 2078 2.24BT_1053 0 0 0.78BT_1054 8 1 0.09BT_1055 1 0 0.10BT_1056 18 0 0.00BT_1057 13 1 0.09BT_1058 865 21912 25.33BT_1059 909 19155 21.07BT_1060 148 160 1.08BT_1061 19 31 1.63BT_1062 47 8 0.17BT_1063 55 17 0.31BT_1064 63 3 0.05BT_1065 0 0 N/DBT_1066 0 0 N/DBT_1067 5 12 2.18BT_1068 3 11 4.23BT_1069 976 734 0.75BT_1070 1702 1711 1.01BT_1071 217 160 0.74BT_1072 13 3 0.26BT_1073 15 3 0.23BT_1074 1 2 2.18BT_1075 0 0 N/DBT_1076 0 0 0.13BT_1077 229 242 1.06BT_1078 157 160 1.02BT_1079 17 15 0.87BT_1080 4 1 0.32

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BT_1081 71 5 0.08BT_1082 20 11 0.54BT_1083 2 1 0.28BT_1084 211 285 1.35BT_1085 613 38 0.06BT_1086 789 436 0.55BT_1087 602 819 1.36BT_1088 189 232 1.23BT_1089 0 5 N/DBT_1090 2 6 3.16BT_1091 67 280 4.20BT_1092 0 0 N/DBT_1093 1 0 0.21BT_1094 3 9 2.97BT_1095 37 19 0.50BT_1096 0 0 N/DBT_1097 0 0 0.18BT_1098 68 106 1.55BT_1099 17 24 1.40BT_1100 104 182 1.75BT_1101 166 165 0.99BT_1102 376 677 1.80BT_1103 185 230 1.24BT_1104 174 209 1.20BT_1105 412 658 1.60BT_1106 871 2017 2.32BT_1107 69 40 0.58BT_1108 33 11 0.32BT_1109 12 30 2.52BT_1110 304 399 1.31BT_1111 336 806 2.40BT_1112 13 11 0.80BT_1113 0 1 N/DBT_1114 10 17 1.77BT_1115 12 42 3.35BT_1116 61 80 1.30BT_1117 15 49 3.38BT_1118 7 10 1.44BT_1119 87 181 2.09BT_1120 11 65 5.71BT_1121 7 3 0.41BT_1122 4 12 3.03BT_1123 53 8 0.15BT_1124 0 0 N/D

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BT_1125 0 0 N/DBT_1126 0 0 N/DBT_1127 2 1 0.94BT_1128 0 0 N/DBT_1129 0 0 0.00BT_1130 0 0 N/DBT_1131 5 7 1.49BT_1132 0 0 N/DBT_1133 1 2 1.71BT_1134 0 0 N/DBT_1135 965 1112 1.15BT_1136 0 0 N/DBT_1137 0 0 N/DBT_1138 0 0 N/DBT_1139 3 9 3.32BT_1140 160 147 0.92BT_1141 35 153 4.42BT_1142 5 49 9.05BT_1143 0 2 N/DBT_1144 767 392 0.51BT_1145 79 41 0.52BT_1146 206 222 1.08BT_1147 831 407 0.49BT_1148 73 52 0.72BT_1149 232 259 1.12BT_1150 30 37 1.22BT_1151 1580 1987 1.26BT_1152 1765 320 0.18BT_1153 5911 700 0.12BT_1154 216 320 1.48BT_1155 443 1 0.00BT_1156 167 0 0.00BT_1157 129 0 0.00BT_1158 401 0 0.00BT_1159 296 1 0.00BT_1160 355 0 0.00BT_1161 143 295 2.07BT_1162 63 270 4.30BT_1163 43 41 0.97BT_1164 15 31 2.06BT_1165 17 2 0.14BT_1166 8 4 0.49BT_1167 7 2 0.23BT_1168 0 0 N/D

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BT_1169 1 0 0.11BT_1170 20 46 2.25BT_1171 22 43 1.90BT_1172 0 1 N/DBT_1173 7 3 0.44BT_1174 51 110 2.17BT_1175 81 177 2.19BT_1176 6 7 1.14BT_1177 2 2 0.92BT_1178 162 103 0.64BT_1179 0 0 N/DBT_1180 1 0 0.13BT_1181 12 2 0.18BT_1182 17 10 0.60BT_1183 8 70 8.92BT_1184 0 0 N/DBT_1185 6629 15570 2.35BT_1186 813 893 1.10BT_1187 35 11 0.32BT_1188 0 0 N/DBT_1189 0 1 N/DBT_1190 17 7 0.39BT_1191 7 2 0.27BT_1192 24 106 4.43BT_1193 74 12 0.16BT_1194 477 708 1.48BT_1195 133 178 1.33BT_1196 24 111 4.58BT_1197 335 2348 7.02BT_1198 327 252 0.77BT_1199 209 339 1.62BT_1200 56 63 1.11BT_1201 11 16 1.43BT_1202 22 17 0.76BT_1203 233 270 1.16BT_1204 804 78 0.10BT_1205 61 37 0.60BT_1206 10 42 4.16BT_1207 210 300 1.42BT_1208 1 8 6.09BT_1209 520 127 0.24BT_1210 241 87 0.36BT_1211 20 8 0.43BT_1212 2 0 0.12

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BT_1213 4 10 2.27BT_1214 8 0 0.03BT_1215 1 1 0.65BT_1216 3 3 0.87BT_1217 1 0 0.22BT_1218 34 139 4.14BT_1219 112 91 0.82BT_1220 699 0 0.00BT_1221 1261 2 0.00BT_1222 1883 3 0.00BT_1223 1 0 0.15BT_1224 182 262 1.44BT_1225 41 25 0.61BT_1226 2483 4435 1.79BT_1227 356 503 1.41BT_1228 1011 980 0.97BT_1229 564 1536 2.72BT_1230 9 34 3.65BT_1231 1 1 0.65BT_1232 22 9 0.38BT_1233 61 181 2.94BT_1234 114 87 0.76BT_1235 17 28 1.66BT_1236 99 260 2.63BT_1237 37 30 0.80BT_1238 106 157 1.49BT_1239 14 2 0.13BT_1240 115 223 1.95BT_1241 1 0 0.00BT_1242 1487 1274 0.86BT_1243 1 0 0.13BT_1244 12 2 0.20BT_1245 0 0 N/DBT_1246 0 0 N/DBT_1247 29 9 0.32BT_1248 47 2 0.03BT_1249 0 0 0.88BT_1250 3 25 7.82BT_1251 202 159 0.79BT_1252 818 1588 1.94BT_1253 187 69 0.37BT_1254 49 23 0.47BT_1255 7 46 6.16BT_1256 227 169 0.74

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BT_1257 11 21 1.99BT_1258 9 28 2.99BT_1259 48 9 0.19BT_1260 57 123 2.17BT_1261 0 1 1.40BT_1262 31 21 0.68BT_1263 0 0 N/DBT_1264 142 22 0.16BT_1265 0 0 N/DBT_1266 20 3 0.15BT_1267 10 5 0.55BT_1268 60 52 0.88BT_1269 77 42 0.54BT_1270 147 48 0.33BT_1271 18 0 0.00BT_1272 983 2182 2.22BT_1273 4 1 0.14BT_1274 0 1 N/DBT_1275 4 19 5.18BT_1276 0 0 N/DBT_1277 5 29 5.51BT_1278 1 0 0.15BT_1279 2 9 5.39BT_1280 10 2 0.19BT_1281 5 0 0.07BT_1282 32 3 0.08BT_1283 26 30 1.14BT_1284 26 32 1.21BT_1285 64 18 0.28BT_1286 44 2 0.04BT_1287 0 0 N/DBT_1288 72 131 1.82BT_1289 51 61 1.19BT_1290 15 31 2.01BT_1291 543 594 1.09BT_1292 1208 488 0.40BT_1293 3863 5 0.00BT_1294 1494 2 0.00BT_1295 171 3 0.02BT_1296 1750 96 0.06BT_1297 233 10 0.04BT_1298 1895 151 0.08BT_1299 1805 181 0.10BT_1300 1434 87 0.06

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BT_1301 947 102 0.11BT_1302 9 4 0.42BT_1303 4 8 2.10BT_1304 405 216 0.53BT_1305 1211 903 0.75BT_1306 1963 2510 1.28BT_1307 154 400 2.60BT_1308 267 1257 4.70BT_1309 712 362 0.51BT_1310 2 10 4.18BT_1311 0 0 N/DBT_1312 773 82 0.11BT_1313 0 0 0.30BT_1314 46 220 4.79BT_1315 223 547 2.45BT_1316 307 727 2.36BT_1317 0 0 N/DBT_1318 51 46 0.91BT_1319 60 224 3.74BT_1320 0 0 N/DBT_1321 17 23 1.33BT_1322 0 1 1.31BT_1323 8 1 0.16BT_1324 86 1156 13.43BT_1325 0 1 N/DBT_1326 299 1 0.00BT_1327 182 0 0.00BT_1328 47 51 1.09BT_1329 334 429 1.28BT_1330 11 10 0.93BT_1331 437 193 0.44BT_1332 404 135 0.33BT_1333 1281 1512 1.18BT_1334 92 286 3.09BT_1335 0 0 0.23BT_1336 72 48 0.67BT_1337 155 598 3.85BT_1338 85 96 1.12BT_1339 221 1 0.00BT_1340 459 3 0.01BT_1341 625 2 0.00BT_1342 524 3 0.01BT_1343 223 2 0.01BT_1344 683 6 0.01

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BT_1345 583 3 0.01BT_1346 578 6 0.01BT_1347 751 7 0.01BT_1348 940 7 0.01BT_1349 395 1 0.00BT_1350 977 9 0.01BT_1351 491 4 0.01BT_1352 555 6 0.01BT_1353 618 9 0.01BT_1354 496 4 0.01BT_1355 370 2 0.01BT_1356 482 11 0.02BT_1357 389 8 0.02BT_1358 368 13 0.03BT_1359 1313 1158 0.88BT_1360 65 21 0.32BT_1361 303 23 0.07BT_1362 0 0 0.61BT_1363 0 0 0.52BT_1364 0 0 0.98BT_1365 12 10 0.81BT_1366 171 481 2.81BT_1367 42 82 1.97BT_1368 0 0 0.51BT_1369 1 0 0.27BT_1370 0 0 N/DBT_1371 893 269 0.30BT_1372 85 290 3.41BT_1373 686 391 0.57BT_1374 532 0 0.00BT_1375 2740 1 0.00BT_1376 166 0 0.00BT_1377 390 0 0.00BT_1378 196 13 0.07BT_1379 103 9 0.09BT_1380 286 22 0.08BT_1381 360 25 0.07BT_1382 71 54 0.77BT_1383 108 32 0.30BT_1384 2 0 0.07BT_1385 23 18 0.77BT_1386 2 1 0.37BT_1387 18 7 0.37BT_1388 1 0 0.13

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BT_1389 17 17 1.00BT_1390 2 15 8.92BT_1391 1014 843 0.83BT_1392 0 0 N/DBT_1393 2 1 0.31BT_1394 12 21 1.69BT_1395 23 27 1.21BT_1396 45 86 1.91BT_1397 0 0 N/DBT_1398 4 8 2.19BT_1399 0 1 N/DBT_1400 51 9 0.18BT_1401 17 35 2.05BT_1402 10 0 0.03BT_1403 25 15 0.60BT_1404 1 0 0.52BT_1405 3 0 0.08BT_1406 1 0 0.26BT_1407 44 11 0.24BT_1408 72 87 1.22BT_1409 2 7 3.47BT_1410 6 22 3.88BT_1411 9 4 0.48BT_1412 1 1 0.58BT_1413 1 0 0.29BT_1414 2763 4679 1.69BT_1415 2050 8047 3.93BT_1416 3628 9914 2.73BT_1417 6673 23593 3.54BT_1418 4456 12310 2.76BT_1419 0 1 2.38BT_1420 0 1 1.96BT_1421 94 258 2.76BT_1422 4 5 1.31BT_1423 0 0 N/DBT_1424 18 6 0.32BT_1425 17 14 0.82BT_1426 1 5 4.51BT_1427 11 1 0.09BT_1428 217 121 0.56BT_1429 14 7 0.45BT_1430 1 6 5.10BT_1431 65 11 0.16BT_1432 129 107 0.83

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BT_1433 128 140 1.10BT_1434 295 311 1.06BT_1435 32 58 1.81BT_1436 31 52 1.70BT_1437 2 1 0.38BT_1438 18 21 1.18BT_1439 126 125 0.99BT_1440 73 325 4.45BT_1441 8 3 0.34BT_1442 187 172 0.92BT_1443 47 21 0.45BT_1444 23 82 3.57BT_1445 47 24 0.51BT_1446 13 37 2.78BT_1447 32 35 1.10BT_1448 19 81 4.27BT_1449 61 179 2.91BT_1450 26 19 0.72BT_1451 34 11 0.32BT_1452 81 53 0.65BT_1453 22 6 0.27BT_1454 0 3 6.32BT_1455 1 0 0.12BT_1456 1 12 9.88BT_1457 61 38 0.62BT_1458 19 2 0.09BT_1459 3 13 4.10BT_1460 79 91 1.15BT_1461 7 3 0.50BT_1462 4 0 0.03BT_1463 7 0 0.03BT_1464 8 36 4.41BT_1465 11 1 0.12BT_1466 0 0 0.66BT_1467 3 1 0.16BT_1468 8 1 0.19BT_1469 1 0 0.00BT_1470 2 2 1.06BT_1471 12 0 0.03BT_1472 12 44 3.52BT_1473 0 0 N/DBT_1474 166 134 0.80BT_1475 0 0 N/DBT_1476 2 0 0.19

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BT_1477 84 141 1.68BT_1478 25 49 1.96BT_1479 84 247 2.94BT_1480 151 73 0.49BT_1481 4 6 1.37BT_1482 0 1 2.57BT_1483 1 1 0.59BT_1484 0 0 N/DBT_1485 125 214 1.71BT_1486 1421 3225 2.27BT_1487 984 1626 1.65BT_1488 906 7823 8.64BT_1489 456 385 0.84BT_1490 919 524 0.57BT_1491 1722 2223 1.29BT_1492 28 69 2.49BT_1493 20 135 6.85BT_1494 31 56 1.82BT_1495 0 0 N/DBT_1496 1 0 0.28BT_1497 0 1 N/DBT_1498 11 12 1.09BT_1499 0 0 N/DBT_1500 2 0 0.06BT_1501 9 0 0.03BT_1502 330 385 1.17BT_1503 39 98 2.51BT_1504 18 0 0.00BT_1505 0 0 N/DBT_1506 52 12 0.23BT_1507 50 89 1.79BT_1508 0 0 N/DBT_1509 6 20 3.29BT_1510 37 50 1.36BT_1511 14 0 0.00BT_1512 30 65 2.19BT_1513 9 42 4.87BT_1514 0 0 0.17BT_1515 6 7 1.29BT_1516 6 1 0.13BT_1517 2 0 0.18BT_1518 6 24 4.30BT_1519 0 0 N/DBT_1520 0 0 N/D

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BT_1521 65 141 2.16BT_1522 32 41 1.30BT_1523 173 99 0.57BT_1524 459 275 0.60BT_1525 134 137 1.02BT_1526 3426 1628 0.48BT_1527 37 8 0.22BT_1528 51 20 0.39BT_1529 86 35 0.41BT_1530 486 18 0.04BT_1531 381 451 1.18BT_1532 112 328 2.92BT_1533 120 369 3.09BT_1534 38 237 6.21BT_1535 36 128 3.58BT_1536 2002 3 0.00BT_1537 180 215 1.20BT_1538 162 3 0.02BT_1539 202 350 1.73BT_1540 166 284 1.71BT_1541 0 0 0.00BT_1542 68 148 2.17BT_1543 8 3 0.34BT_1544 53 82 1.54BT_1545 158 99 0.63BT_1546 9 3 0.40BT_1547 2 3 1.12BT_1548 601 1 0.00BT_1549 547 844 1.54BT_1550 119 199 1.67BT_1551 444 1046 2.35BT_1552 694 1606 2.31BT_1553 421 959 2.28BT_1554 38 2 0.06BT_1555 15 25 1.65BT_1556 1 2 2.08BT_1557 88 155 1.75BT_1558 1418 1584 1.12BT_1559 6 43 7.68BT_1560 307 61 0.20BT_1561 136 28 0.21BT_1562 70 197 2.83BT_1563 27 11 0.42BT_1564 50 24 0.48

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BT_1565 1 0 0.13BT_1566 83 57 0.69BT_1567 151 76 0.51BT_1568 135 12 0.09BT_1569 1324 565 0.43BT_1570 50 88 1.75BT_1571 2 2 1.17BT_1572 14 0 0.01BT_1573 2 4 2.51BT_1574 2753 3852 1.40BT_1575 3 0 0.10BT_1576 104 208 2.00BT_1577 58 58 0.99BT_1578 49 21 0.43BT_1579 1257 680 0.54BT_1580 229 122 0.53BT_1581 335 374 1.12BT_1582 149 120 0.81BT_1583 234 207 0.88BT_1584 0 0 N/DBT_1585 0 0 N/DBT_1586 21 8 0.37BT_1587 6 10 1.75BT_1588 22 9 0.41BT_1589 0 0 N/DBT_1590 26 3 0.10BT_1591 62 23 0.37BT_1592 232 1 0.00BT_1593 0 1 N/DBT_1594 83 48 0.58BT_1595 0 1 N/DBT_1596 13 4 0.29BT_1597 36 1 0.03BT_1598 26 5 0.20BT_1599 101 219 2.16BT_1600 46 20 0.43BT_1601 0 0 1.06BT_1602 0 0 N/DBT_1603 0 0 N/DBT_1604 32 3 0.09BT_1605 67 3 0.05BT_1606 0 0 N/DBT_1607 1081 0 0.00BT_1608 5 8 1.67

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BT_1609 42 84 2.01BT_1610 1 1 0.68BT_1611 11 3 0.25BT_1612 151 367 2.42BT_1613 2117 143 0.07BT_1614 283 10 0.03BT_1615 1388 622 0.45BT_1616 52 94 1.82BT_1617 41 48 1.16BT_1618 38 57 1.51BT_1619 34 62 1.83BT_1620 23 1 0.03BT_1621 8 10 1.24BT_1622 34 65 1.89BT_1623 13 35 2.57BT_1624 13 29 2.21BT_1625 26 21 0.80BT_1626 10 1 0.07BT_1627 7 8 1.04BT_1628 13 11 0.85BT_1629 48 30 0.62BT_1630 70 4 0.06BT_1631 68 44 0.64BT_1632 151 104 0.69BT_1633 20 26 1.27BT_1634 57 84 1.49BT_1635 77 28 0.36BT_1636 39 22 0.58BT_1637 2 1 0.36BT_1638 18 20 1.09BT_1639 2 6 2.98BT_1640 0 0 N/DBT_1641 0 0 N/DBT_1642 23 29 1.29BT_1643 0 0 0.13BT_1644 11 13 1.21BT_1645 6 1 0.19BT_1646 0 10 24.41BT_1647 24 3 0.14BT_1648 27 21 0.78BT_1649 9 76 8.41BT_1650 89 85 0.95BT_1651 119 59 0.50BT_1652 96 14 0.15

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BT_1653 57 101 1.77BT_1654 20 1 0.05BT_1655 0 0 N/DBT_1656 0 0 N/DBT_1657 0 0 N/DBT_1658 57 142 2.50BT_1659 110 196 1.78BT_1660 53 13 0.24BT_1661 97 84 0.87BT_1662 24 48 1.97BT_1663 233 191 0.82BT_1664 47 0 0.00BT_1665 41 0 0.01BT_1666 4 12 2.98BT_1667 52 50 0.96BT_1668 170 326 1.91BT_1669 2 0 0.25BT_1670 63 86 1.36BT_1671 19 28 1.52BT_1672 0 1 1.32BT_1673 22 54 2.39BT_1674 0 3 7.07BT_1675 125 46 0.37BT_1676 332 287 0.86BT_1677 16 1 0.04BT_1678 20 0 0.00BT_1679 11 0 0.01BT_1680 2 1 0.29BT_1681 72 90 1.24BT_1682 101 29 0.28BT_1683 22 13 0.62BT_1684 21 5 0.22BT_1685 121 0 0.00BT_1686 1609 1 0.00BT_1687 807 0 0.00BT_1688 522 0 0.00BT_1689 1901 151 0.08BT_1690 43 52 1.22BT_1691 1 1 0.97BT_1692 3 0 0.02BT_1693 0 1 1.44BT_1694 17 18 1.03BT_1695 0 0 0.77BT_1696 872 1351 1.55

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BT_1697 1172 1817 1.55BT_1698 154 229 1.49BT_1699 0 0 0.36BT_1700 0 0 N/DBT_1701 11 0 0.01BT_1702 17 0 0.00BT_1703 17 9 0.53BT_1704 0 0 N/DBT_1705 0 0 N/DBT_1706 0 0 N/DBT_1707 495 507 1.03BT_1708 1 0 0.22BT_1709 11 4 0.34BT_1710 17 10 0.62BT_1711 0 0 N/DBT_1712 47 14 0.30BT_1713 2 6 2.52BT_1714 176 16 0.09BT_1715 4 0 0.02BT_1716 31 9 0.30BT_1717 15 7 0.49BT_1718 14 7 0.50BT_1719 67 34 0.50BT_1720 36 15 0.43BT_1721 11 2 0.16BT_1722 37 2 0.06BT_1723 0 0 0.68BT_1724 0 0 0.00BT_1725 1 0 0.53BT_1726 0 0 N/DBT_1727 180 232 1.29BT_1728 230 508 2.21BT_1729 629 600 0.95BT_1730 121 0 0.00BT_1731 72 0 0.00BT_1732 0 1 N/DBT_1733 5089 1 0.00BT_1734 102 53 0.51BT_1735 28 32 1.14BT_1736 6 55 8.54BT_1737 264 262 0.99BT_1738 20 3 0.12BT_1739 712 247 0.35BT_1740 368 502 1.37

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BT_1741 104 144 1.39BT_1742 74 181 2.45BT_1743 1 0 0.31BT_1744 65 163 2.49BT_1745 11 2 0.18BT_1746 1158 30 0.03BT_1747 16210 1 0.00BT_1748 1 0 0.07BT_1749 152 104 0.68BT_1750 2 1 0.35BT_1751 1 15 19.24BT_1752 36 59 1.65BT_1753 1 1 0.65BT_1754 42 10 0.25BT_1755 9 4 0.45BT_1756 0 0 N/DBT_1757 26 0 0.01BT_1758 0 0 0.90BT_1759 22 1 0.04BT_1760 69 30 0.44BT_1761 43 22 0.52BT_1762 28 5 0.19BT_1763 127 9 0.07BT_1764 2 6 2.64BT_1765 86 1314 15.25BT_1766 35 49 1.38BT_1767 6 16 2.53BT_1768 18 25 1.36BT_1769 89 32 0.36BT_1770 338 579 1.71BT_1771 40 44 1.11BT_1772 7 14 2.16BT_1773 36 45 1.24BT_1774 132 29 0.22BT_1775 123 94 0.76BT_1776 98 96 0.97BT_1777 36 25 0.70BT_1778 31 15 0.47BT_1779 9 1 0.13BT_1780 2 3 2.04BT_1781 0 0 N/DBT_1782 33 58 1.74BT_1783 32 25 0.79BT_1784 4 18 5.16

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BT_1785 2 1 0.70BT_1786 9 0 0.02BT_1787 60 3 0.05BT_1788 0 1 2.05BT_1789 2967 1112 0.37BT_1790 12 16 1.33BT_1791 37 42 1.12BT_1792 155 2288 14.72BT_1793 8 32 3.95BT_1794 4 0 0.07BT_1795 5 3 0.63BT_1796 12 7 0.54BT_1797 42 86 2.06BT_1798 360 752 2.09BT_1799 419 1182 2.82BT_1800 37 8 0.21BT_1801 111 3 0.03BT_1802 79 235 2.97BT_1803 8 2 0.19BT_1804 790 1 0.00BT_1805 1471 1 0.00BT_1806 2275 1 0.00BT_1807 124 14 0.12BT_1808 28 1 0.04BT_1809 102 34 0.33BT_1810 17 20 1.17BT_1811 40 92 2.28BT_1812 10 39 3.82BT_1813 33 9 0.28BT_1814 101 51 0.51BT_1815 49 57 1.17BT_1816 76 16 0.21BT_1817 0 2 N/DBT_1818 272 0 0.00BT_1819 84 129 1.54BT_1820 75 87 1.16BT_1821 0 0 N/DBT_1822 0 0 N/DBT_1823 0 0 N/DBT_1824 44 3 0.06BT_1825 10 27 2.80BT_1826 73 34 0.47BT_1827 1 10 11.70BT_1828 1 1 0.63

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BT_1829 0 0 N/DBT_1830 0 0 N/DBT_1831 39 8 0.21BT_1832 0 1 2.56BT_1833 151 248 1.64BT_1834 311 425 1.37BT_1835 119 172 1.44BT_1836 19 24 1.27BT_1837 15 11 0.71BT_1838 69 23 0.33BT_1839 4 4 0.93BT_1840 0 2 5.68BT_1841 243 241 0.99BT_1842 17 6 0.38BT_1843 2169 0 0.00BT_1844 927 1 0.00BT_1845 2 2 1.33BT_1846 87 18 0.21BT_1847 2 0 0.04BT_1848 2 0 0.00BT_1849 0 0 N/DBT_1850 4 2 0.38BT_1851 100 83 0.82BT_1852 60 46 0.76BT_1853 109 70 0.64BT_1854 27 8 0.32BT_1855 8 14 1.67BT_1856 84 166 1.96BT_1857 212 10 0.04BT_1858 155 25 0.16BT_1859 92 9 0.10BT_1860 283 19 0.07BT_1861 287 34 0.12BT_1862 28 90 3.21BT_1863 0 0 N/DBT_1864 0 0 N/DBT_1865 0 0 N/DBT_1866 0 0 N/DBT_1867 0 0 N/DBT_1868 0 0 N/DBT_1869 0 0 N/DBT_1870 0 0 N/DBT_1871 3870 3675 0.95BT_1872 1728 2142 1.24

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BT_1873 0 0 N/DBT_1874 24 12 0.53BT_1875 37 15 0.41BT_1876 602 1398 2.32BT_1877 0 1 N/DBT_1878 584 781 1.34BT_1879 1 1 0.67BT_1880 0 0 0.26BT_1881 193 1 0.01BT_1882 267 1 0.00BT_1883 133 365 2.75BT_1884 60 143 2.38BT_1885 94 204 2.18BT_1886 48 78 1.63BT_1887 113 131 1.15BT_1888 30 45 1.51BT_1889 1 6 5.41BT_1890 64 170 2.64BT_1891 0 0 N/DBT_1892 0 0 N/DBT_1893 0 0 N/DBT_1894 36 39 1.10BT_1895 1158 3634 3.14BT_1896 2158 7698 3.57BT_1897 182 395 2.17BT_1898 90 206 2.28BT_1899 9 3 0.33BT_1900 79 5 0.07BT_1901 14 6 0.45BT_1902 5 0 0.06BT_1903 0 0 N/DBT_1904 29 20 0.70BT_1905 0 0 0.13BT_1906 29 10 0.35BT_1907 5 0 0.03BT_1908 17 9 0.54BT_1909 0 0 N/DBT_1910 14 67 4.79BT_1911 17 6 0.35BT_1912 18 58 3.26BT_1913 0 1 3.09BT_1914 0 0 N/DBT_1915 816 1509 1.85BT_1916 337 267 0.79

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BT_1917 716 739 1.03BT_1918 65 15 0.23BT_1919 1 2 1.43BT_1920 229 430 1.88BT_1921 15 42 2.70BT_1922 25 26 1.02BT_1923 1770 3222 1.82BT_1924 17 2 0.10BT_1925 0 0 N/DBT_1926 12 0 0.00BT_1927 19 26 1.36BT_1928 0 0 N/DBT_1929 0 0 N/DBT_1930 0 0 N/DBT_1931 151 110 0.73BT_1932 2 4 1.64BT_1933 1 0 0.00BT_1934 61 88 1.46BT_1935 83 9 0.11BT_1936 31 86 2.73BT_1937 199 280 1.41BT_1938 67 41 0.61BT_1939 125 73 0.58BT_1940 56 23 0.42BT_1941 11 2 0.21BT_1942 0 0 N/DBT_1943 0 0 N/DBT_1944 6 0 0.00BT_1945 0 0 N/DBT_1946 9 4 0.48BT_1947 0 0 N/DBT_1948 0 0 N/DBT_1949 5 5 1.07BT_1950 0 0 N/DBT_1951 15 14 0.97BT_1952 137 223 1.62BT_1953 85 90 1.06BT_1954 312 212 0.68BT_1955 2629 1408 0.54BT_1956 3868 2464 0.64BT_1957 2430 2387 0.98BT_1958 5 0 0.09BT_1959 0 0 N/DBT_1960 0 0 0.18

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BT_1961 0 0 N/DBT_1962 11 2 0.22BT_1963 1 0 0.00BT_1964 0 0 N/DBT_1965 30 33 1.10BT_1966 54 26 0.49BT_1967 5 4 0.86BT_1968 94 74 0.79BT_1969 462 339 0.73BT_1970 1748 1562 0.89BT_1971 45 52 1.16BT_1972 40 10 0.24BT_1973 844 444 0.53BT_1974 905 4352 4.81BT_1975 1 0 0.16BT_1976 216 0 0.00BT_1977 148 165 1.11BT_1978 106 0 0.00BT_1979 655 357 0.55BT_1980 23 4 0.18BT_1981 0 1 N/DBT_1982 0 0 N/DBT_1983 20 15 0.74BT_1984 28 15 0.53BT_1985 518 254 0.49BT_1986 0 0 N/DBT_1987 0 1 1.59BT_1988 0 0 N/DBT_1989 1 1 0.63BT_1990 0 0 N/DBT_1991 0 0 N/DBT_1992 106 64 0.61BT_1993 189 56 0.29BT_1994 9 1 0.13BT_1995 33 14 0.41BT_1996 0 0 N/DBT_1997 151 179 1.18BT_1998 30 25 0.82BT_1999 13 36 2.79BT_2000 58 148 2.56BT_2001 2 0 0.08BT_2002 0 0 N/DBT_2003 0 0 0.00BT_2004 0 0 N/D

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BT_2005 0 0 N/DBT_2006 0 0 N/DBT_2007 0 0 0.44BT_2008 0 0 N/DBT_2009 0 0 N/DBT_2010 0 0 N/DBT_2011 0 0 0.88BT_2012 9 17 1.85BT_2013 47 105 2.25BT_2014 0 0 0.00BT_2015 0 0 N/DBT_2016 1 0 0.15BT_2017 0 0 N/DBT_2018 25 165 6.47BT_2019 1 0 0.00BT_2020 6 7 1.17BT_2021 1 0 0.00BT_2022 0 0 N/DBT_2023 53 146 2.77BT_2024 0 0 N/DBT_2025 10 17 1.72BT_2026 12 0 0.03BT_2027 0 73 N/DBT_2028 2 2 0.79BT_2029 0 0 N/DBT_2030 322 441 1.37BT_2031 555 678 1.22BT_2032 208 745 3.58BT_2033 276 1836 6.64BT_2034 333 2240 6.73BT_2035 559 711 1.27BT_2036 57 134 2.34BT_2037 192 337 1.76BT_2038 419 111 0.26BT_2039 727 374 0.51BT_2040 75 1 0.01BT_2041 35 88 2.51BT_2042 47 11 0.23BT_2043 5 4 0.83BT_2044 23 116 5.09BT_2045 0 0 0.58BT_2046 61 29 0.47BT_2047 0 0 0.26BT_2048 0 0 N/D

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BT_2049 508 9 0.02BT_2050 71 161 2.27BT_2051 99 200 2.03BT_2052 1448 0 0.00BT_2053 993 0 0.00BT_2054 1116 0 0.00BT_2055 1803 0 0.00BT_2056 158 73 0.46BT_2057 445 900 2.02BT_2058 106 0 0.00BT_2059 178 0 0.00BT_2060 0 0 N/DBT_2061 0 0 N/DBT_2062 1149 28 0.02BT_2063 14 1 0.05BT_2064 27 58 2.15BT_2065 55 71 1.28BT_2066 0 0 N/DBT_2067 9 0 0.04BT_2068 32 14 0.44BT_2069 28 19 0.66BT_2070 263 586 2.23BT_2071 43 93 2.16BT_2072 73 135 1.84BT_2073 2 1 0.48BT_2074 1122 28 0.02BT_2075 128 7 0.06BT_2076 159 26 0.17BT_2077 439 43 0.10BT_2078 561 71 0.13BT_2079 768 739 0.96BT_2080 236 492 2.09BT_2081 69 58 0.84BT_2082 4 24 6.64BT_2083 0 0 0.44BT_2084 631 1 0.00BT_2085 246 335 1.36BT_2086 28 7 0.24BT_2087 0 1 1.32BT_2088 6 22 3.33BT_2089 2 1 0.31BT_2090 2547 7 0.00BT_2091 1261 8 0.01BT_2092 1425 2184 1.53

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BT_2093 267 183 0.68BT_2094 87 146 1.68BT_2095 50 67 1.35BT_2096 665 606 0.91BT_2097 87 49 0.56BT_2098 99 237 2.40BT_2099 28 24 0.85BT_2100 3 4 1.36BT_2101 11 4 0.34BT_2102 37 30 0.81BT_2103 660 38 0.06BT_2104 23 28 1.20BT_2105 52 75 1.44BT_2106 102 223 2.20BT_2107 62 35 0.56BT_2108 5 3 0.48BT_2109 66 647 9.79BT_2110 28 60 2.12BT_2111 30 15 0.49BT_2112 107 21 0.19BT_2113 58 2 0.03BT_2114 0 0 N/DBT_2115 109 40 0.36BT_2116 134 124 0.93BT_2117 26 14 0.54BT_2118 72 68 0.94BT_2119 15 14 0.96BT_2120 15 21 1.35BT_2121 49 82 1.68BT_2122 1 1 0.86BT_2123 0 0 N/DBT_2124 1 0 0.00BT_2125 184 145 0.79BT_2126 404 1131 2.80BT_2127 198 129 0.65BT_2128 400 617 1.54BT_2129 255 473 1.85BT_2130 20 10 0.54BT_2131 0 0 N/DBT_2132 10 6 0.65BT_2133 2 1 0.36BT_2134 100 37 0.37BT_2135 2 1 0.23BT_2136 140 116 0.83

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BT_2137 0 0 N/DBT_2138 0 0 N/DBT_2139 24 28 1.16BT_2140 76 50 0.66BT_2141 329 301 0.91BT_2142 717 434 0.61BT_2143 1 0 0.34BT_2144 267 385 1.44BT_2145 3420 5 0.00BT_2146 27 1 0.04BT_2147 50 19 0.38BT_2148 6 16 2.84BT_2149 0 0 N/DBT_2150 283 316 1.12BT_2151 0 0 N/DBT_2152 0 1 N/DBT_2153 0 0 0.63BT_2154 907 1246 1.37BT_2155 287 397 1.38BT_2156 783 703 0.90BT_2157 994 412 0.41BT_2158 469 93 0.20BT_2159 1795 3913 2.18BT_2160 1875 8713 4.65BT_2161 80 2 0.03BT_2162 0 0 N/DBT_2163 1 0 0.00BT_2164 175 70 0.40BT_2165 0 0 0.68BT_2166 0 0 N/DBT_2167 6 1 0.25BT_2168 23 16 0.68BT_2169 7 6 0.81BT_2170 18 104 5.64BT_2171 1147 730 0.64BT_2172 32 5 0.17BT_2173 14 40 2.80BT_2174 17 7 0.42BT_2175 23 3 0.11BT_2176 43 51 1.19BT_2177 3 4 1.59BT_2178 314 221 0.70BT_2179 152 255 1.67BT_2180 14 29 2.12

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BT_2181 1 0 0.00BT_2182 0 0 N/DBT_2183 2 1 0.44BT_2184 0 0 N/DBT_2185 63 1 0.01BT_2186 41 1 0.02BT_2187 108 54 0.50BT_2188 0 1 1.71BT_2189 4 5 1.41BT_2190 0 0 1.00BT_2191 39 5 0.12BT_2192 0 0 0.18BT_2193 4 2 0.54BT_2194 16 25 1.55BT_2195 1 0 0.42BT_2196 38 58 1.52BT_2197 20 3 0.15BT_2198 0 2 N/DBT_2199 38 58 1.54BT_2200 25 18 0.71BT_2201 3 2 0.56BT_2202 145 63 0.43BT_2203 15 19 1.32BT_2204 42 39 0.94BT_2205 2 0 0.11BT_2206 0 0 0.68BT_2207 0 0 N/DBT_2208 62 78 1.26BT_2209 55 80 1.45BT_2210 90 74 0.82BT_2211 4 20 4.65BT_2212 73 185 2.54BT_2213 21 111 5.29BT_2214 51 225 4.42BT_2215 339 511 1.51BT_2216 13 36 2.67BT_2217 13 12 0.93BT_2218 0 0 0.40BT_2219 44 29 0.66BT_2220 33 25 0.76BT_2221 33 13 0.40BT_2222 0 0 N/DBT_2223 142 67 0.47BT_2224 7 11 1.54

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BT_2225 10 7 0.64BT_2226 92 58 0.63BT_2227 9 50 5.58BT_2228 620 196 0.32BT_2229 67 0 0.00BT_2230 2 1 0.63BT_2231 1 0 0.00BT_2232 0 0 N/DBT_2233 14 39 2.85BT_2234 115 3 0.03BT_2235 99 9 0.09BT_2236 0 0 N/DBT_2237 0 0 N/DBT_2238 0 0 0.59BT_2239 243 309 1.27BT_2240 80 22 0.27BT_2241 13 0 0.04BT_2242 0 0 N/DBT_2243 9 6 0.73BT_2244 1 0 0.11BT_2245 38 1 0.04BT_2246 1 0 0.13BT_2247 3 0 0.00BT_2248 24 200 8.44BT_2249 1 0 0.00BT_2250 0 2 N/DBT_2251 9 0 0.02BT_2252 35 40 1.16BT_2253 0 0 0.75BT_2254 58 12 0.20BT_2255 1 1 0.70BT_2256 1 0 0.40BT_2257 181 567 3.13BT_2258 222 156 0.70BT_2259 2115 2931 1.39BT_2260 3836 6613 1.72BT_2261 864 1586 1.84BT_2262 793 335 0.42BT_2263 1823 1698 0.93BT_2264 3718 4255 1.14BT_2265 0 0 N/DBT_2266 2 4 2.74BT_2267 12 1 0.06BT_2268 3168 4559 1.44

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BT_2269 1933 2525 1.31BT_2270 17 12 0.75BT_2271 4 20 5.54BT_2272 817 370 0.45BT_2273 525 262 0.50BT_2274 214 75 0.35BT_2275 33 66 2.00BT_2276 55 104 1.88BT_2277 3 1 0.46BT_2278 9 16 1.81BT_2279 19 31 1.61BT_2280 2 1 0.20BT_2281 0 0 N/DBT_2282 2 29 14.26BT_2283 0 0 N/DBT_2284 0 0 N/DBT_2285 2 0 0.00BT_2286 0 0 N/DBT_2287 3 15 5.27BT_2288 0 0 N/DBT_2289 13 1 0.09BT_2290 0 0 0.60BT_2291 2 0 0.25BT_2292 0 0 N/DBT_2293 0 0 N/DBT_2294 0 0 N/DBT_2295 0 0 N/DBT_2296 0 0 N/DBT_2297 10 9 0.88BT_2298 31 47 1.53BT_2299 0 0 N/DBT_2300 5 57 11.00BT_2301 86 0 0.00BT_2302 0 0 N/DBT_2303 1 0 0.00BT_2304 117 16 0.14BT_2305 6 13 2.11BT_2306 14 1 0.04BT_2307 9 30 3.25BT_2308 4 4 1.08BT_2309 0 0 N/DBT_2310 13 9 0.70BT_2311 0 0 0.33BT_2312 6 31 5.45

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BT_2313 69 29 0.42BT_2314 0 0 N/DBT_2315 0 0 N/DBT_2316 25 28 1.12BT_2317 0 0 N/DBT_2318 0 0 N/DBT_2319 3 5 1.68BT_2320 21 15 0.73BT_2321 0 0 N/DBT_2322 3 1 0.29BT_2323 0 0 N/DBT_2324 6 1 0.10BT_2325 0 0 0.00BT_2326 15 9 0.55BT_2327 17 28 1.67BT_2328 56 72 1.29BT_2329 30 52 1.73BT_2330 292 276 0.95BT_2331 212 439 2.07BT_2332 0 0 0.00BT_2333 15 13 0.85BT_2334 0 0 N/DBT_2335 0 0 0.00BT_2336 1 0 0.00BT_2337 1 0 0.00BT_2338 39 23 0.58BT_2339 0 0 N/DBT_2340 24 4 0.16BT_2341 62 109 1.76BT_2342 0 0 0.31BT_2343 33 9 0.28BT_2344 0 0 N/DBT_2345 39 11 0.29BT_2346 1 0 0.22BT_2347 1 0 0.00BT_2348 1 0 0.20BT_2349 8 0 0.00BT_2350 0 0 N/DBT_2351 0 0 N/DBT_2352 0 0 N/DBT_2353 1235 2081 1.69BT_2354 1880 2102 1.12BT_2355 120 160 1.33BT_2356 11 34 3.03

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BT_2357 39 55 1.40BT_2358 9 16 1.78BT_2359 5 22 4.91BT_2360 279 309 1.11BT_2361 678 473 0.70BT_2362 1 1 0.87BT_2363 0 1 3.51BT_2364 42 7 0.16BT_2365 10 14 1.35BT_2366 48 26 0.56BT_2367 132 4 0.03BT_2368 7 2 0.36BT_2369 4 38 10.05BT_2370 50 69 1.39BT_2371 19 13 0.66BT_2372 0 0 N/DBT_2373 34 134 3.94BT_2374 156 203 1.31BT_2375 0 0 N/DBT_2376 0 0 0.57BT_2377 11 17 1.60BT_2378 2 0 0.11BT_2379 28 0 0.02BT_2380 23 21 0.90BT_2381 0 0 N/DBT_2382 11 1 0.06BT_2383 0 0 N/DBT_2384 0 0 N/DBT_2385 0 0 N/DBT_2386 90 53 0.59BT_2387 16 3 0.22BT_2388 10 2 0.18BT_2389 822 747 0.91BT_2390 11 36 3.25BT_2391 164 504 3.07BT_2392 11 4 0.35BT_2393 55 183 3.31BT_2394 26 0 0.00BT_2395 3 0 0.16BT_2396 30 12 0.40BT_2397 13 3 0.26BT_2398 0 0 N/DBT_2399 0 0 N/DBT_2400 86 83 0.96

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BT_2401 430 451 1.05BT_2402 341 326 0.96BT_2403 709 11 0.02BT_2404 5 32 6.58BT_2405 97 2 0.02BT_2406 28 4 0.14BT_2407 7 0 0.02BT_2408 1 0 0.08BT_2409 42 2 0.04BT_2410 33 53 1.61BT_2411 23 64 2.83BT_2412 44 34 0.77BT_2413 205 12 0.06BT_2414 884 1 0.00BT_2415 1757 5 0.00BT_2416 0 0 1.07BT_2417 1 1 0.89BT_2418 98 322 3.28BT_2419 1626 1460 0.90BT_2420 10 4 0.41BT_2421 70 94 1.34BT_2422 16 1 0.04BT_2423 0 0 N/DBT_2424 8 8 1.02BT_2425 11 4 0.35BT_2426 0 0 N/DBT_2427 0 0 N/DBT_2428 0 0 N/DBT_2429 0 0 0.91BT_2430 6 10 1.63BT_2431 0 3 5.93BT_2432 25 21 0.83BT_2433 22 79 3.65BT_2434 454 510 1.12BT_2435 119 28 0.23BT_2436 1 0 0.34BT_2437 145 166 1.14BT_2438 290 188 0.65BT_2439 74 148 2.01BT_2440 23 81 3.49BT_2441 124 143 1.15BT_2442 1 0 0.30BT_2443 38 77 2.02BT_2444 55 172 3.10

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BT_2445 0 0 N/DBT_2446 0 0 N/DBT_2447 52 27 0.52BT_2448 0 0 N/DBT_2449 0 0 0.18BT_2450 193 407 2.11BT_2451 45 142 3.14BT_2452 42 353 8.51BT_2453 0 2 5.47BT_2454 0 3 N/DBT_2455 24 0 0.00BT_2456 0 0 N/DBT_2457 12 8 0.70BT_2458 15 56 3.74BT_2459 29 2 0.07BT_2460 65 73 1.12BT_2461 15 4 0.28BT_2462 15 21 1.35BT_2463 0 0 0.70BT_2464 0 0 N/DBT_2465 1 0 0.12BT_2466 1 5 6.35BT_2467 1 2 1.97BT_2468 1 0 0.12BT_2469 0 0 N/DBT_2470 10 10 1.02BT_2471 0 0 N/DBT_2472 0 0 N/DBT_2473 2 1 0.73BT_2474 41 13 0.33BT_2475 16 40 2.41BT_2476 149 17 0.11BT_2477 4 292 72.56BT_2478 5 3 0.65BT_2479 29 63 2.22BT_2480 2 5 2.33BT_2481 1 0 0.28BT_2482 12 11 0.93BT_2483 0 0 N/DBT_2484 8 30 3.93BT_2485 19 5 0.24BT_2486 109 29 0.27BT_2487 0 0 N/DBT_2488 17 39 2.25

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BT_2489 44 1 0.03BT_2490 1 0 0.14BT_2491 454 0 0.00BT_2492 1 1 0.68BT_2493 0 1 2.40BT_2494 9 25 2.95BT_2495 31 24 0.76BT_2496 28 12 0.41BT_2497 25 57 2.32BT_2498 34 79 2.31BT_2499 45 5 0.11BT_2500 18 8 0.44BT_2501 12 1 0.06BT_2502 109 119 1.10BT_2503 13 34 2.60BT_2504 14 62 4.45BT_2505 222 365 1.64BT_2506 1 0 0.25BT_2507 4 14 3.93BT_2508 47 74 1.56BT_2509 29 4 0.13BT_2510 878 268 0.30BT_2511 2 7 2.84BT_2512 19 1 0.07BT_2513 10 18 1.79BT_2514 18 14 0.76BT_2515 0 2 N/DBT_2516 3 28 10.05BT_2517 0 1 N/DBT_2518 1 0 0.14BT_2519 0 0 N/DBT_2520 0 2 N/DBT_2521 0 1 N/DBT_2522 483 462 0.96BT_2523 53 60 1.13BT_2524 5 4 0.74BT_2525 1 1 1.34BT_2526 524 667 1.27BT_2527 282 450 1.60BT_2528 69 9 0.13BT_2529 20 1 0.06BT_2530 15 1 0.04BT_2531 4 13 3.16BT_2532 257 553 2.15

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BT_2533 0 0 N/DBT_2534 0 0 N/DBT_2535 5 7 1.43BT_2536 0 1 1.63BT_2537 2 1 0.60BT_2538 18 92 5.23BT_2539 345 411 1.19BT_2540 62 166 2.66BT_2541 3 1 0.27BT_2542 0 0 N/DBT_2543 1 0 0.55BT_2544 388 22 0.06BT_2545 233 404 1.73BT_2546 123 175 1.42BT_2547 0 0 N/DBT_2548 1 0 0.10BT_2549 2 9 3.79BT_2550 26 9 0.33BT_2551 34 81 2.39BT_2552 23 85 3.68BT_2553 62 54 0.87BT_2554 32 27 0.85BT_2555 0 5 N/DBT_2556 0 0 N/DBT_2557 0 0 N/DBT_2558 0 0 N/DBT_2559 37 0 0.01BT_2560 25 22 0.86BT_2561 21 12 0.57BT_2562 123 155 1.26BT_2563 230 1 0.00BT_2564 1563 2037 1.30BT_2565 444 2 0.00BT_2566 183 102 0.56BT_2567 38 5 0.13BT_2568 37 5 0.12BT_2569 23 9 0.39BT_2570 11 48 4.22BT_2571 18 12 0.68BT_2572 0 0 N/DBT_2573 65 249 3.83BT_2574 18 4 0.20BT_2575 2 0 0.00BT_2576 1 0 0.15

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BT_2577 95 118 1.24BT_2578 89 123 1.38BT_2579 79 174 2.18BT_2580 0 0 0.00BT_2581 8 6 0.69BT_2582 0 0 N/DBT_2583 20 1 0.03BT_2584 1 0 0.17BT_2585 32 4 0.12BT_2586 0 0 N/DBT_2587 52 2 0.03BT_2588 94 70 0.74BT_2589 0 0 N/DBT_2590 0 0 N/DBT_2591 1 0 0.00BT_2592 19 12 0.60BT_2593 43 33 0.79BT_2594 15 0 0.02BT_2595 0 0 N/DBT_2596 0 1 N/DBT_2597 0 0 N/DBT_2598 0 0 N/DBT_2599 2 5 2.66BT_2600 0 0 0.00BT_2601 0 0 0.00BT_2602 75 8 0.11BT_2603 0 0 N/DBT_2604 11 0 0.01BT_2605 0 0 0.46BT_2606 12 12 1.02BT_2607 11 0 0.03BT_2608 0 0 N/DBT_2609 11 0 0.03BT_2610 0 3 N/DBT_2611 0 0 N/DBT_2612 6 0 0.03BT_2613 55 31 0.57BT_2614 71 5 0.08BT_2615 10 26 2.54BT_2616 0 0 N/DBT_2617 14 5 0.32BT_2618 61 42 0.69BT_2619 69 80 1.16BT_2620 212 86 0.41

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BT_2621 39 64 1.65BT_2622 42 58 1.41BT_2623 38 40 1.04BT_2624 10 27 2.58BT_2625 64 102 1.60BT_2626 98 136 1.39BT_2627 59 51 0.86BT_2628 66 19 0.29BT_2629 99 89 0.90BT_2630 304 235 0.77BT_2631 108 122 1.13BT_2632 39 66 1.68BT_2633 9 1 0.08BT_2634 66 22 0.33BT_2635 38 12 0.32BT_2636 4 2 0.53BT_2637 0 0 N/DBT_2638 28 37 1.30BT_2639 3 6 1.98BT_2640 21 2 0.08BT_2641 12 10 0.76BT_2642 2 3 1.45BT_2643 0 0 N/DBT_2644 0 1 N/DBT_2645 0 0 N/DBT_2646 0 0 N/DBT_2647 1 0 0.35BT_2648 14 2 0.11BT_2649 0 0 0.00BT_2650 9 4 0.47BT_2651 22 16 0.72BT_2652 0 0 N/DBT_2653 1 0 0.32BT_2654 8 26 3.03BT_2655 43 53 1.24BT_2656 49 76 1.56BT_2657 26 24 0.91BT_2658 199 293 1.47BT_2659 31 48 1.53BT_2660 29 2 0.08BT_2661 103 223 2.17BT_2662 716 1069 1.49BT_2663 1 7 5.61BT_2664 10 129 12.66

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BT_2665 109 12 0.11BT_2666 7 1 0.17BT_2667 1 0 0.00BT_2668 20 24 1.21BT_2669 1039 979 0.94BT_2671 0 0 N/DBT_2672 0 0 N/DBT_2673 0 0 N/DBT_2674 0 0 N/DBT_2675 1 7 5.61BT_2676 1 0 0.26BT_2677 0 1 N/DBT_2678 71 57 0.81BT_2679 3 22 7.75BT_2680 102 319 3.13BT_2681 6 6 0.95BT_2682 9 6 0.66BT_2683 89 39 0.44BT_2684 48 42 0.88BT_2685 175 65 0.37BT_2686 864 827 0.96BT_2687 391 517 1.32BT_2688 276 410 1.49BT_2689 611 256 0.42BT_2690 17 13 0.78BT_2691 6 0 0.02BT_2692 70 146 2.08BT_2693 32 114 3.54BT_2694 4 5 1.26BT_2695 526 683 1.30BT_2696 1 0 0.00BT_2697 19 109 5.70BT_2698 9 7 0.78BT_2699 438 284 0.65BT_2700 0 0 N/DBT_2701 0 1 N/DBT_2702 0 0 0.30BT_2703 0 0 N/DBT_2704 1 0 0.24BT_2705 0 0 N/DBT_2706 1 1 1.15BT_2707 0 1 3.20BT_2708 0 0 N/DBT_2709 0 0 N/D

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BT_2710 0 0 1.11BT_2711 0 0 0.00BT_2712 0 0 N/DBT_2713 0 0 N/DBT_2714 0 0 N/DBT_2715 0 0 N/DBT_2716 0 0 N/DBT_2717 0 1 2.14BT_2718 0 0 N/DBT_2719 0 0 N/DBT_2720 0 0 N/DBT_2721 1 0 0.51BT_2722 0 0 N/DBT_2723 2 0 0.17BT_2724 1 0 0.15BT_2725 0 0 N/DBT_2726 0 1 N/DBT_2727 0 0 N/DBT_2728 0 0 N/DBT_2729 0 1 N/DBT_2730 0 0 N/DBT_2731 1 0 0.17BT_2732 420 456 1.09BT_2733 1 2 2.53BT_2734 1 1 1.33BT_2735 0 0 N/DBT_2736 0 0 N/DBT_2737 0 0 N/DBT_2738 0 0 N/DBT_2739 0 0 N/DBT_2740 0 1 N/DBT_2741 2183 723 0.33BT_2742 1643 7 0.00BT_2743 86 224 2.59BT_2744 48 56 1.18BT_2745 1 0 0.39BT_2746 17 35 2.02BT_2747 1 0 0.20BT_2748 0 0 N/DBT_2749 141 59 0.42BT_2750 67 104 1.55BT_2751 279 514 1.84BT_2752 0 1 N/DBT_2753 1146 1184 1.03

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BT_2754 0 0 0.13BT_2755 70 65 0.94BT_2756 65 167 2.58BT_2757 235 714 3.04BT_2758 11 60 5.25BT_2759 0 0 N/DBT_2760 51 12 0.23BT_2761 1 0 0.15BT_2762 59 32 0.54BT_2763 0 0 N/DBT_2764 15 2 0.15BT_2765 1 0 0.17BT_2766 0 0 0.44BT_2767 0 0 N/DBT_2768 16 1 0.05BT_2769 168 130 0.77BT_2770 160 116 0.73BT_2771 17 2 0.11BT_2772 74 48 0.65BT_2773 12 17 1.36BT_2774 23 15 0.67BT_2775 86 38 0.44BT_2776 0 2 3.86BT_2777 69 79 1.14BT_2778 87 38 0.44BT_2779 4 21 5.64BT_2780 39 14 0.35BT_2781 1030 225 0.22BT_2782 1430 2959 2.07BT_2783 570 616 1.08BT_2784 0 0 0.26BT_2785 99 26 0.26BT_2786 3 0 0.06BT_2787 1436 1280 0.89BT_2788 9 41 4.59BT_2789 0 0 0.72BT_2790 2 2 0.89BT_2791 322 300 0.93BT_2792 1 14 16.00BT_2793 10 6 0.64BT_2794 25 16 0.65BT_2795 1 5 4.52BT_2796 1 0 0.41BT_2797 0 1 N/D

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BT_2798 1423 118 0.08BT_2799 402 719 1.79BT_2800 0 1 N/DBT_2801 49 76 1.53BT_2802 14 3 0.20BT_2803 2 2 1.19BT_2804 6 0 0.05BT_2805 34 4 0.12BT_2806 101 104 1.02BT_2807 4 6 1.34BT_2808 1 1 0.77BT_2809 22 25 1.17BT_2810 10 18 1.74BT_2811 6 37 6.59BT_2812 19 9 0.45BT_2813 0 0 N/DBT_2814 43 23 0.53BT_2815 7 21 3.12BT_2816 1148 1150 1.00BT_2817 736 1436 1.95BT_2818 152 311 2.04BT_2819 2 0 0.28BT_2820 34 29 0.84BT_2821 37 18 0.50BT_2822 1 1 0.70BT_2823 11 3 0.23BT_2824 44 18 0.40BT_2825 20 3 0.17BT_2826 152 85 0.56BT_2827 5 1 0.19BT_2828 75 24 0.32BT_2829 1 1 1.23BT_2830 1836 1585 0.86BT_2831 6 2 0.36BT_2832 62 5 0.08BT_2833 4 1 0.18BT_2834 126 234 1.86BT_2835 2 1 0.64BT_2836 759 205 0.27BT_2837 358 121 0.34BT_2838 0 0 N/DBT_2839 0 0 N/DBT_2840 0 0 N/DBT_2841 0 0 0.48

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BT_2842 0 0 N/DBT_2843 10 0 0.01BT_2844 4825 11 0.00BT_2845 312 216 0.69BT_2846 8 7 0.85BT_2847 30 63 2.12BT_2848 35 4 0.12BT_2849 73 0 0.01BT_2850 589 657 1.11BT_2851 6 1 0.17BT_2852 104 46 0.44BT_2853 0 0 N/DBT_2854 81 1 0.01BT_2855 8 1 0.18BT_2856 29 74 2.60BT_2857 10 2 0.21BT_2858 75 23 0.31BT_2859 138 95 0.69BT_2860 38 94 2.49BT_2861 59 71 1.21BT_2862 34 21 0.61BT_2863 75 24 0.32BT_2864 112 51 0.45BT_2865 9 35 3.74BT_2866 12 10 0.90BT_2867 15 8 0.50BT_2868 71 40 0.56BT_2869 116 32 0.28BT_2870 7 8 1.15BT_2871 28 15 0.53BT_2872 104 2 0.02BT_2873 8 3 0.42BT_2874 42 228 5.44BT_2875 0 0 N/DBT_2876 7 1 0.14BT_2877 1 0 0.28BT_2878 198 208 1.05BT_2879 121 62 0.51BT_2880 28 32 1.15BT_2881 42 8 0.19BT_2882 30 15 0.50BT_2883 0 0 N/DBT_2884 29 10 0.35BT_2885 79 78 0.98

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BT_2886 45 63 1.39BT_2887 6 4 0.57BT_2888 29 2 0.06BT_2889 4 4 0.89BT_2890 19 5 0.28BT_2891 2 0 0.09BT_2892 27 210 7.69BT_2893 11 3 0.25BT_2894 51 139 2.73BT_2895 0 0 1.10BT_2896 35 3 0.08BT_2897 130 134 1.04BT_2898 0 1 N/DBT_2899 9 1 0.10BT_2900 14 1 0.09BT_2901 4 9 2.57BT_2902 0 0 N/DBT_2903 70 1 0.01BT_2904 44 0 0.01BT_2905 151 159 1.05BT_2906 129 179 1.39BT_2907 20 28 1.37BT_2908 103 99 0.96BT_2909 107 13 0.13BT_2910 32 39 1.22BT_2911 98 11 0.11BT_2912 204 118 0.58BT_2913 75 10 0.13BT_2914 10 12 1.17BT_2915 1 2 1.88BT_2916 31 50 1.61BT_2917 10 0 0.03BT_2918 15 0 0.03BT_2919 17 15 0.89BT_2920 135 68 0.50BT_2921 7 1 0.19BT_2922 2 2 1.18BT_2923 124 191 1.54BT_2924 948 1238 1.31BT_2925 0 0 N/DBT_2926 11 35 3.23BT_2927 159 182 1.14BT_2928 100 22 0.22BT_2929 0 1 N/D

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BT_2930 0 0 N/DBT_2931 0 0 N/DBT_2932 126 1 0.01BT_2933 1 0 0.30BT_2934 51 0 0.00BT_2935 5 1 0.15BT_2936 25 12 0.48BT_2937 4 1 0.19BT_2938 31 3 0.10BT_2939 0 0 N/DBT_2940 2 1 0.71BT_2941 0 1 N/DBT_2942 29 10 0.35BT_2943 116 213 1.84BT_2944 127 54 0.42BT_2945 466 208 0.45BT_2946 105 0 0.00BT_2947 67 1 0.01BT_2948 4 1 0.36BT_2949 22 17 0.74BT_2950 13 5 0.40BT_2951 8 1 0.09BT_2952 122 94 0.77BT_2953 5 1 0.28BT_2954 46 222 4.81BT_2955 8 0 0.04BT_2956 3 2 0.73BT_2957 4 4 0.83BT_2958 95 75 0.80BT_2959 112 288 2.57BT_2960 18 0 0.01BT_2961 6 19 2.89BT_2962 1 0 0.07BT_2963 59 5 0.08BT_2964 65 12 0.18BT_2965 2 16 7.91BT_2966 63 20 0.32BT_2967 3 1 0.43BT_2968 112 166 1.48BT_2969 7 12 1.62BT_2970 76 77 1.02BT_2971 111 275 2.48BT_2972 191 76 0.40BT_2973 0 0 N/D

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BT_2974 4 13 2.94BT_2975 84 109 1.30BT_2976 922 29 0.03BT_2977 3226 215 0.07BT_2978 172 8 0.05BT_2979 88 203 2.31BT_2980 27 11 0.40BT_2981 114 97 0.85BT_2982 1 0 0.52BT_2983 7 2 0.29BT_2984 38 4 0.10BT_2985 0 0 0.49BT_2986 15 29 1.96BT_2987 6 1 0.15BT_2988 80 12 0.15BT_2989 32 35 1.10BT_2990 78 34 0.43BT_2991 21 4 0.19BT_2992 41 60 1.46BT_2993 36 0 0.00BT_2994 0 0 N/DBT_2995 0 0 N/DBT_2996 0 0 N/DBT_2997 256 441 1.72BT_2998 87 121 1.39BT_2999 49 139 2.85BT_3000 83 73 0.89BT_3001 137 208 1.51BT_3002 26 14 0.51BT_3003 1403 2035 1.45BT_3004 59 9 0.15BT_3005 84 32 0.39BT_3006 26 3 0.13BT_3007 3 9 3.39BT_3008 21 14 0.68BT_3009 86 16 0.18BT_3010 28 84 2.97BT_3011 3 4 1.18BT_3012 58 22 0.38BT_3013 3 1 0.50BT_3014 0 0 0.44BT_3015 33 0 0.01BT_3016 38 39 1.02BT_3017 130 217 1.67

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BT_3018 33 6 0.18BT_3019 2 14 5.77BT_3020 1 4 2.94BT_3021 8 1 0.09BT_3022 46 22 0.49BT_3023 22 1 0.04BT_3024 64 31 0.48BT_3025 0 0 0.75BT_3026 1 5 4.31BT_3027 93 2 0.02BT_3028 1 0 0.33BT_3029 21 15 0.69BT_3030 17 1 0.04BT_3031 0 1 N/DBT_3032 96 5 0.05BT_3033 2 2 1.02BT_3034 0 0 N/DBT_3035 157 533 3.39BT_3036 1 0 0.23BT_3037 2 2 0.83BT_3038 33 2 0.08BT_3039 8 11 1.40BT_3040 95 170 1.79BT_3041 17 25 1.44BT_3042 46 41 0.89BT_3043 1 1 1.12BT_3044 0 0 N/DBT_3045 9 12 1.40BT_3046 43 20 0.45BT_3047 83 38 0.45BT_3048 7 11 1.51BT_3049 50 8 0.15BT_3050 44 12 0.27BT_3051 220 304 1.38BT_3052 141 129 0.91BT_3053 1 0 0.08BT_3054 0 1 N/DBT_3055 0 0 N/DBT_3056 1 1 0.76BT_3057 1 3 2.70BT_3058 53 79 1.48BT_3059 36 51 1.44BT_3060 0 0 0.00BT_3061 0 0 N/D

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BT_3062 1 1 1.01BT_3063 1 0 0.00BT_3064 14 15 1.04BT_3065 22 20 0.90BT_3066 82 72 0.88BT_3067 112 202 1.80BT_3068 0 0 N/DBT_3069 7 8 1.22BT_3070 31 51 1.64BT_3071 173 361 2.09BT_3072 387 29 0.08BT_3073 114 19 0.17BT_3074 131 68 0.52BT_3075 119 93 0.79BT_3076 0 0 N/DBT_3077 147 105 0.72BT_3078 251 239 0.95BT_3079 9 8 0.89BT_3080 859 427 0.50BT_3081 3 8 2.47BT_3082 53 11 0.21BT_3083 181 98 0.54BT_3084 88 82 0.94BT_3085 32 38 1.18BT_3086 39 8 0.19BT_3087 60 34 0.57BT_3088 17 39 2.21BT_3089 1 0 0.44BT_3090 13 15 1.22BT_3091 1 14 12.10BT_3092 10 1 0.09BT_3093 10 5 0.51BT_3094 26 9 0.36BT_3095 0 0 0.76BT_3096 30 17 0.58BT_3097 84 40 0.47BT_3098 6 8 1.47BT_3099 0 0 N/DBT_3100 7 13 1.88BT_3101 2 0 0.12BT_3102 45 1 0.02BT_3103 132 74 0.56BT_3104 17 8 0.47BT_3105 62 170 2.74

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BT_3106 57 1 0.02BT_3107 9 2 0.18BT_3108 101 10 0.10BT_3109 32 0 0.01BT_3110 74 127 1.71BT_3111 19 2 0.08BT_3112 26 3 0.10BT_3113 237 280 1.18BT_3114 78 18 0.23BT_3115 18 2 0.10BT_3116 0 1 N/DBT_3117 0 0 N/DBT_3118 0 0 1.04BT_3119 55 44 0.79BT_3120 115 54 0.47BT_3121 570 1030 1.81BT_3122 3 0 0.13BT_3123 1 1 0.83BT_3124 51 167 3.24BT_3125 0 0 N/DBT_3126 2 0 0.15BT_3127 105 103 0.98BT_3128 2 4 1.55BT_3129 226 653 2.88BT_3130 7 2 0.30BT_3131 9 12 1.40BT_3132 1 0 0.24BT_3133 52 50 0.96BT_3134 72 18 0.24BT_3135 0 1 N/DBT_3136 7 20 2.85BT_3137 0 0 N/DBT_3138 2240 1977 0.88BT_3139 0 0 N/DBT_3140 0 2 N/DBT_3141 0 0 N/DBT_3142 0 0 N/DBT_3143 0 1 N/DBT_3144 0 0 N/DBT_3145 439 429 0.98BT_3146 703 5754 8.19BT_3147 2022 1878 0.93BT_3148 1098 1507 1.37BT_3149 309 302 0.98

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BT_3150 127 246 1.94BT_3151 56 92 1.65BT_3152 173 238 1.38BT_3153 22 25 1.12BT_3154 1 12 14.34BT_3155 32 20 0.65BT_3156 80 16 0.20BT_3157 50 2 0.05BT_3158 42 341 8.08BT_3159 5 55 10.44BT_3160 6 57 8.85BT_3161 8 0 0.04BT_3162 0 1 1.82BT_3163 2 6 2.72BT_3164 68 123 1.80BT_3165 8 31 4.04BT_3166 48 130 2.69BT_3167 43 40 0.93BT_3168 17 2 0.12BT_3169 88 49 0.56BT_3170 31 14 0.46BT_3171 5 0 0.09BT_3172 33 30 0.90BT_3173 2 1 0.22BT_3174 80 28 0.35BT_3175 0 0 N/DBT_3176 11 18 1.71BT_3177 1 1 0.82BT_3178 2 1 0.51BT_3179 42 6 0.15BT_3180 7 0 0.03BT_3181 99 293 2.97BT_3182 1222 565 0.46BT_3183 116 114 0.99BT_3184 246 230 0.93BT_3185 40 16 0.40BT_3186 169 95 0.56BT_3187 74 431 5.79BT_3188 43 43 0.99BT_3189 126 78 0.62BT_3190 1 1 0.95BT_3191 418 1 0.00BT_3192 251 178 0.71BT_3193 1184 34 0.03

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BT_3194 0 0 N/DBT_3195 248 196 0.79BT_3196 0 0 N/DBT_3197 0 0 N/DBT_3198 9 3 0.30BT_3199 0 0 N/DBT_3200 3 25 9.95BT_3201 247 106 0.43BT_3202 25 4 0.15BT_3203 17 21 1.19BT_3204 0 0 N/DBT_3205 5 31 5.78BT_3206 8 8 0.99BT_3207 4 1 0.31BT_3208 0 0 N/DBT_3209 0 0 N/DBT_3210 0 0 N/DBT_3211 0 0 N/DBT_3212 0 0 1.08BT_3213 1 0 0.14BT_3214 2 1 0.28BT_3215 0 0 N/DBT_3216 0 0 0.21BT_3217 85 238 2.78BT_3218 54 61 1.13BT_3219 0 0 N/DBT_3220 10 19 1.92BT_3221 95 12 0.13BT_3222 12 6 0.51BT_3223 11 25 2.25BT_3224 12 1 0.08BT_3225 4 0 0.03BT_3226 0 0 N/DBT_3227 0 0 N/DBT_3228 68 36 0.53BT_3229 0 0 N/DBT_3230 0 0 0.17BT_3231 122 26 0.22BT_3232 363 98 0.27BT_3233 2 2 0.99BT_3234 25 6 0.24BT_3235 271 136 0.50BT_3236 257 236 0.92BT_3237 147 147 1.00

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BT_3238 392 382 0.97BT_3239 530 897 1.69BT_3240 576 2019 3.51BT_3241 309 1025 3.32BT_3242 216 662 3.06BT_3243 353 896 2.54BT_3244 77 153 1.99BT_3245 6 5 0.74BT_3246 3 1 0.18BT_3247 711 20 0.03BT_3248 26 9 0.33BT_3249 32 25 0.79BT_3250 77 41 0.54BT_3251 71 66 0.93BT_3252 65 3 0.05BT_3253 118 1 0.00BT_3254 256 1 0.00BT_3255 373 1 0.00BT_3256 27 0 0.00BT_3257 106 75 0.70BT_3258 1 0 0.32BT_3259 560 385 0.69BT_3260 78 1 0.01BT_3261 1 0 0.33BT_3262 4 11 2.77BT_3263 1314 1242 0.94BT_3264 62 40 0.65BT_3265 61 35 0.57BT_3266 124 42 0.34BT_3267 317 393 1.24BT_3268 179 5 0.03BT_3269 32 95 3.02BT_3270 165 272 1.65BT_3271 73 125 1.71BT_3272 54 7 0.14BT_3273 22 41 1.84BT_3274 26 14 0.55BT_3275 5 2 0.55BT_3276 158 83 0.53BT_3277 21 34 1.67BT_3278 2 0 0.00BT_3279 102 25 0.24BT_3280 0 1 N/DBT_3281 5 20 3.71

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BT_3282 22 15 0.71BT_3283 0 0 0.13BT_3284 0 0 N/DBT_3285 0 0 N/DBT_3286 1 0 0.54BT_3287 0 0 0.96BT_3288 11 62 5.63BT_3289 34 146 4.36BT_3290 15 5 0.30BT_3291 13 20 1.48BT_3292 80 60 0.75BT_3293 200 66 0.33BT_3294 13 24 1.79BT_3295 61 24 0.39BT_3296 12 15 1.26BT_3297 46 3 0.07BT_3298 45 76 1.69BT_3299 115 20 0.17BT_3300 148 113 0.76BT_3301 47 23 0.49BT_3302 94 46 0.48BT_3303 543 467 0.86BT_3304 102 208 2.05BT_3305 973 1484 1.52BT_3306 0 0 0.00BT_3307 2 0 0.03BT_3308 6 17 2.95BT_3309 26 11 0.45BT_3310 19 5 0.27BT_3311 39 38 0.97BT_3312 133 94 0.71BT_3313 19 63 3.27BT_3314 4 13 3.07BT_3315 7 0 0.03BT_3316 1 0 0.00BT_3317 1 0 0.32BT_3318 12 6 0.50BT_3319 0 1 N/DBT_3320 0 0 N/DBT_3321 99 105 1.07BT_3322 9 22 2.52BT_3323 0 0 N/DBT_3324 72 24 0.34BT_3325 112 121 1.08

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BT_3326 9 24 2.63BT_3327 14 19 1.34BT_3328 4 19 5.10BT_3329 103 48 0.47BT_3330 3 5 1.49BT_3331 4 0 0.07BT_3332 6 5 0.82BT_3333 2 0 0.10BT_3334 29 90 3.11BT_3335 296 400 1.35BT_3336 440 101 0.23BT_3337 512 2 0.00BT_3338 1471 892 0.61BT_3339 603 224 0.37BT_3340 294 461 1.57BT_3341 278 0 0.00BT_3342 456 152 0.33BT_3343 58 52 0.91BT_3344 25 5 0.21BT_3345 2 3 1.67BT_3346 23 10 0.45BT_3347 26 35 1.32BT_3348 147 29 0.20BT_3349 12 4 0.31BT_3350 8 22 2.70BT_3351 1 0 0.32BT_3352 7 16 2.24BT_3353 82 37 0.45BT_3354 21 21 1.04BT_3355 463 3 0.01BT_3356 48 92 1.91BT_3357 1443 1453 1.01BT_3358 1 1 0.71BT_3359 0 0 N/DBT_3360 12 26 2.12BT_3361 89 45 0.50BT_3362 18 1 0.04BT_3363 127 0 0.00BT_3364 67 0 0.00BT_3365 350 1 0.00BT_3366 486 1 0.00BT_3367 179 1 0.01BT_3368 66 1 0.02BT_3369 142 6 0.04

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BT_3370 336 11 0.03BT_3371 145 5 0.03BT_3372 61 4 0.06BT_3373 113 17 0.15BT_3374 136 22 0.16BT_3375 274 29 0.11BT_3376 330 37 0.11BT_3377 91 201 2.21BT_3378 29 12 0.41BT_3379 34 13 0.39BT_3380 15 2 0.15BT_3381 212 303 1.43BT_3382 84 192 2.29BT_3383 40 98 2.42BT_3384 34 54 1.59BT_3385 0 1 N/DBT_3386 0 1 N/DBT_3387 238 1305 5.47BT_3388 198 790 3.99BT_3389 56 276 4.96BT_3390 4 21 4.72BT_3391 4 0 0.00BT_3392 102 154 1.50BT_3393 142 0 0.00BT_3394 437 1 0.00BT_3395 134 1 0.00BT_3396 157 417 2.66BT_3397 1555 4267 2.74BT_3398 0 0 N/DBT_3399 3 5 1.78BT_3400 98 63 0.64BT_3401 123 374 3.04BT_3402 0 0 0.65BT_3403 2 0 0.20BT_3404 1 1 0.61BT_3405 16 10 0.66BT_3406 0 1 1.41BT_3407 0 0 N/DBT_3408 1 0 0.63BT_3409 1 0 0.22BT_3410 15 31 2.05BT_3411 190 85 0.45BT_3412 30 82 2.71BT_3413 1107 1838 1.66

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BT_3414 253 590 2.33BT_3415 0 0 N/DBT_3416 0 0 N/DBT_3417 14 3 0.23BT_3418 5 6 1.12BT_3419 59 4 0.07BT_3420 12 0 0.03BT_3421 59 73 1.24BT_3422 119 24 0.20BT_3423 4 16 4.56BT_3424 18 1 0.04BT_3425 34 182 5.41BT_3426 0 0 N/DBT_3427 81 120 1.48BT_3428 61 143 2.34BT_3429 0 0 0.95BT_3430 15 0 0.01BT_3431 189 5 0.03BT_3432 1 1 1.75BT_3433 10 11 1.06BT_3434 3 15 4.63BT_3435 0 0 N/DBT_3436 7 0 0.01BT_3437 98 60 0.61BT_3438 2 7 3.35BT_3439 65 35 0.54BT_3440 72 87 1.21BT_3441 0 0 N/DBT_3442 42 1 0.03BT_3443 95 122 1.27BT_3444 1 1 0.72BT_3445 1 1 0.72BT_3446 0 0 N/DBT_3447 0 0 N/DBT_3448 0 0 0.58BT_3449 0 1 N/DBT_3450 0 0 N/DBT_3451 0 0 N/DBT_3452 0 1 1.33BT_3453 0 1 N/DBT_3454 0 0 N/DBT_3455 0 1 N/DBT_3456 0 0 N/DBT_3457 370 246 0.66

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BT_3458 23 0 0.02BT_3459 216 5 0.02BT_3460 51 25 0.50BT_3461 0 0 0.63BT_3462 2 0 0.26BT_3463 1 0 0.09BT_3464 207 234 1.13BT_3465 211 915 4.33BT_3466 1 1 0.70BT_3467 4 6 1.60BT_3468 9 2 0.25BT_3469 188 309 1.64BT_3470 147 143 0.98BT_3471 15 15 0.99BT_3472 28 119 4.22BT_3473 39 17 0.43BT_3474 57 2 0.04BT_3475 89 34 0.38BT_3476 12 4 0.32BT_3477 77 23 0.29BT_3478 210 337 1.61BT_3479 0 0 N/DBT_3480 0 0 N/DBT_3481 0 0 0.00BT_3482 29 18 0.62BT_3483 7 2 0.36BT_3484 0 1 1.94BT_3485 68 35 0.52BT_3486 4 1 0.33BT_3487 89 32 0.35BT_3488 63 205 3.24BT_3489 25 4 0.17BT_3490 155 153 0.99BT_3491 1 0 0.57BT_3492 4 18 4.09BT_3493 29 12 0.42BT_3494 15 82 5.54BT_3495 68 24 0.36BT_3496 50 11 0.22BT_3497 62 430 6.96BT_3498 11 7 0.69BT_3499 0 0 0.51BT_3500 62 15 0.24BT_3501 9 16 1.72

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BT_3502 1 0 0.16BT_3503 0 0 N/DBT_3504 0 0 0.41BT_3505 35 36 1.02BT_3506 47 14 0.30BT_3507 26 23 0.88BT_3508 39 47 1.20BT_3509 21 2 0.08BT_3510 0 0 N/DBT_3511 1 13 15.18BT_3512 51 1 0.02BT_3513 0 1 N/DBT_3514 29 8 0.28BT_3515 191 221 1.15BT_3516 8 12 1.54BT_3517 4 4 1.01BT_3518 963 481 0.50BT_3519 71 12 0.16BT_3520 37 2 0.06BT_3521 92 80 0.87BT_3522 72 29 0.40BT_3523 3 1 0.47BT_3524 39 70 1.81BT_3525 11 3 0.31BT_3526 25 50 2.01BT_3527 33 22 0.65BT_3528 35 1 0.01BT_3529 0 0 N/DBT_3530 2 0 0.14BT_3531 1 0 0.46BT_3532 1 0 0.10BT_3533 31 8 0.26BT_3534 1 1 0.73BT_3535 10 2 0.24BT_3536 11 8 0.69BT_3537 44 82 1.87BT_3538 0 1 N/DBT_3539 25 9 0.38BT_3540 35 0 0.01BT_3541 5 0 0.04BT_3542 10 0 0.03BT_3543 6 0 0.07BT_3544 1 0 0.13BT_3545 5 1 0.19

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BT_3546 18 31 1.74BT_3547 0 0 0.45BT_3548 50 163 3.27BT_3549 74 0 0.00BT_3550 760 84 0.11BT_3551 43 145 3.38BT_3552 1 0 0.15BT_3553 5 1 0.25BT_3554 27 4 0.15BT_3555 27 61 2.31BT_3556 220 766 3.48BT_3557 1 11 12.96BT_3558 1788 1327 0.74BT_3559 1390 1887 1.36BT_3560 8109 3410 0.42BT_3561 2366 680 0.29BT_3562 5673 2655 0.47BT_3563 384 560 1.46BT_3564 0 0 N/DBT_3565 30 8 0.26BT_3566 16 0 0.01BT_3567 15 14 0.93BT_3568 48 77 1.59BT_3569 12 11 0.98BT_3570 43 37 0.86BT_3571 0 0 N/DBT_3572 1 1 0.68BT_3573 0 1 N/DBT_3574 5 2 0.30BT_3575 32 0 0.00BT_3576 75 71 0.95BT_3577 46 84 1.82BT_3578 57 56 0.98BT_3579 0 1 N/DBT_3581 2 1 0.51BT_3582 0 0 0.00BT_3583 0 0 N/DBT_3584 0 1 1.66BT_3585 7 8 1.21BT_3586 0 1 N/DBT_3587 0 0 N/DBT_3588 153 17 0.11BT_3589 13 3 0.24BT_3590 41 6 0.15

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BT_3591 0 2 5.82BT_3592 5 1 0.17BT_3593 17 9 0.56BT_3594 32 29 0.90BT_3595 5 18 3.33BT_3596 109 47 0.43BT_3597 20 1 0.03BT_3598 15 35 2.37BT_3599 45 22 0.49BT_3600 4 1 0.17BT_3601 128 41 0.32BT_3602 22 11 0.50BT_3603 25 17 0.70BT_3604 163 10109 61.88BT_3605 0 3 7.46BT_3606 1 0 0.16BT_3607 50 14 0.28BT_3608 38 4 0.10BT_3609 16 32 2.00BT_3610 21 9 0.41BT_3611 1 0 0.36BT_3612 687 193 0.28BT_3613 1 0 0.53BT_3614 0 2 N/DBT_3615 0 1 1.42BT_3616 22 3 0.14BT_3617 0 0 N/DBT_3618 0 0 0.39BT_3619 13 7 0.52BT_3620 42 5 0.11BT_3621 23 18 0.79BT_3622 65 137 2.11BT_3623 52 43 0.82BT_3624 10 2 0.24BT_3625 48 80 1.67BT_3626 10 0 0.02BT_3627 0 0 N/DBT_3628 7 0 0.05BT_3629 0 0 0.00BT_3630 38 3 0.08BT_3631 48 18 0.37BT_3632 44 18 0.41BT_3633 81 67 0.83BT_3634 0 0 N/D

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BT_3635 0 0 N/DBT_3636 0 0 N/DBT_3637 57 72 1.27BT_3638 2 1 0.47BT_3639 0 0 N/DBT_3640 0 0 N/DBT_3641 0 0 N/DBT_3642 48 18 0.38BT_3643 2 9 5.65BT_3644 0 0 N/DBT_3645 25 2 0.07BT_3646 0 0 N/DBT_3647 1 0 0.15BT_3648 653 551 0.84BT_3649 399 440 1.10BT_3650 0 0 N/DBT_3651 25 10 0.40BT_3652 1 0 0.31BT_3653 0 0 N/DBT_3654 138 11 0.08BT_3655 6 0 0.04BT_3656 37 118 3.18BT_3657 21 6 0.28BT_3658 1 0 0.00BT_3659 18 10 0.59BT_3660 87 22 0.26BT_3661 0 0 N/DBT_3662 5 4 0.97BT_3663 2 1 0.40BT_3664 1 1 0.97BT_3665 34 4 0.11BT_3666 0 0 N/DBT_3667 40 1 0.03BT_3668 0 0 N/DBT_3669 9 3 0.34BT_3670 41 21 0.51BT_3671 76 38 0.49BT_3672 8 27 3.24BT_3673 1 1 1.86BT_3674 103 54 0.52BT_3675 39 37 0.96BT_3676 7 5 0.66BT_3677 10 8 0.75BT_3678 72 16 0.22

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BT_3679 2 0 0.00BT_3680 34 29 0.86BT_3681 15 57 3.87BT_3682 19 14 0.71BT_3683 1 1 0.43BT_3684 0 0 N/DBT_3685 17 4 0.23BT_3686 28 1 0.04BT_3687 9 19 2.19BT_3688 14 11 0.84BT_3689 519 470 0.91BT_3690 12 32 2.58BT_3691 21 9 0.45BT_3692 0 0 N/DBT_3693 9 0 0.04BT_3694 5 0 0.09BT_3695 0 1 1.24BT_3696 0 0 N/DBT_3697 0 0 N/DBT_3698 265 468 1.77BT_3699 509 3420 6.72BT_3700 358 912 2.55BT_3701 4 17 4.19BT_3702 105 87 0.82BT_3703 46 15 0.34BT_3704 612 1102 1.80BT_3705 24 91 3.79BT_3706 0 0 N/DBT_3707 0 0 N/DBT_3708 507 723 1.43BT_3709 342 0 0.00BT_3710 100 121 1.20BT_3711 0 0 N/DBT_3712 0 0 N/DBT_3713 0 0 N/DBT_3714 0 0 1.11BT_3715 233 204 0.87BT_3716 117 111 0.95BT_3717 156 0 0.00BT_3718 32 0 0.01BT_3719 1 0 0.34BT_3720 52 68 1.32BT_3721 163 251 1.53BT_3722 0 0 N/D

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BT_3723 0 1 N/DBT_3724 956 5 0.00BT_3725 2 2 0.98BT_3726 0 0 N/DBT_3727 2 0 0.19BT_3728 0 0 N/DBT_3729 70 1699 24.42BT_3730 110 47 0.43BT_3731 849 1 0.00BT_3732 196 0 0.00BT_3733 696 0 0.00BT_3734 6 1 0.16BT_3735 2 0 0.06BT_3736 32 0 0.00BT_3737 0 0 0.75BT_3738 35 145 4.13BT_3739 10 24 2.31BT_3740 22 5 0.23BT_3741 31 18 0.57BT_3742 2188 3557 1.63BT_3743 3326 2302 0.69BT_3744 686 415 0.61BT_3745 581 473 0.82BT_3746 30 214 7.23BT_3747 0 0 0.13BT_3748 8 9 1.05BT_3749 0 2 5.06BT_3750 25 30 1.22BT_3751 19 106 5.47BT_3752 12 21 1.77BT_3753 9 6 0.59BT_3754 0 0 N/DBT_3755 417 458 1.10BT_3756 116 262 2.25BT_3757 46 62 1.35BT_3758 193 0 0.00BT_3759 362 0 0.00BT_3760 216 0 0.00BT_3761 40 0 0.01BT_3762 295 0 0.00BT_3763 24 0 0.00BT_3764 21 0 0.02BT_3765 0 0 N/DBT_3766 4 1 0.22

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BT_3767 2 13 7.78BT_3768 164 163 0.99BT_3769 0 0 N/DBT_3770 0 0 N/DBT_3771 0 0 N/DBT_3772 1474 1132 0.77BT_3773 277 410 1.48BT_3774 22 63 2.81BT_3775 3 1 0.41BT_3776 0 1 1.76BT_3777 0 0 N/DBT_3778 132 29 0.22BT_3779 73 13 0.17BT_3780 0 0 0.44BT_3781 17 16 0.94BT_3782 23 66 2.95BT_3783 116 297 2.56BT_3784 43 57 1.34BT_3785 0 0 N/DBT_3786 70 33 0.46BT_3787 11 5 0.41BT_3788 75 135 1.81BT_3789 62 82 1.33BT_3790 8 7 0.95BT_3791 11 74 6.58BT_3792 168 114 0.67BT_3793 79 85 1.08BT_3794 53 129 2.43BT_3795 0 0 N/DBT_3796 0 0 N/DBT_3797 0 0 N/DBT_3798 0 0 0.69BT_3799 18 2 0.11BT_3800 93 16 0.18BT_3801 201 74 0.37BT_3802 574 200 0.35BT_3803 732 345 0.47BT_3804 149 468 3.15BT_3805 42 14 0.33BT_3806 223 9 0.04BT_3807 263 3 0.01BT_3808 1 0 0.09BT_3809 121 358 2.97BT_3810 362 63 0.17

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BT_3811 1533 489 0.32BT_3812 0 0 N/DBT_3813 0 1 N/DBT_3814 0 0 N/DBT_3815 0 0 N/DBT_3816 2 0 0.28BT_3817 0 0 N/DBT_3818 4 0 0.02BT_3819 34 0 0.01BT_3820 0 0 N/DBT_3821 0 0 N/DBT_3822 0 1 2.09BT_3823 11 5 0.44BT_3824 4 0 0.07BT_3825 0 0 N/DBT_3826 0 0 N/DBT_3827 0 0 N/DBT_3828 0 0 N/DBT_3829 0 0 N/DBT_3830 0 0 N/DBT_3831 0 0 N/DBT_3832 0 0 N/DBT_3833 0 0 N/DBT_3834 0 1 N/DBT_3835 0 1 N/DBT_3836 0 0 N/DBT_3837 0 0 N/DBT_3838 254 242 0.95BT_3839 289 313 1.08BT_3840 740 558 0.75BT_3841 2062 1418 0.69BT_3842 143 6 0.04BT_3843 851 477 0.56BT_3844 600 0 0.00BT_3845 2341 2 0.00BT_3846 34 105 3.12BT_3847 0 0 N/DBT_3848 1 1 0.65BT_3849 0 0 0.96BT_3850 0 0 0.00BT_3851 44 2 0.05BT_3852 838 119 0.14BT_3853 151 112 0.74BT_3854 19 60 3.21

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BT_3855 3 4 1.42BT_3856 0 0 N/DBT_3857 0 0 0.52BT_3858 2 1 0.40BT_3859 118 0 0.00BT_3860 65 23 0.35BT_3861 36 0 0.01BT_3862 16 3 0.21BT_3863 1 11 13.80BT_3864 0 0 1.02BT_3865 1 1 0.84BT_3866 6954 6833 0.98BT_3867 637 761 1.19BT_3868 0 0 N/DBT_3869 1 12 9.17BT_3870 8 14 1.87BT_3871 20 1 0.04BT_3872 0 0 N/DBT_3873 0 0 N/DBT_3874 275 328 1.19BT_3875 0 0 N/DBT_3876 0 0 0.17BT_3877 1 0 0.39BT_3878 2 1 0.62BT_3879 74 149 2.01BT_3880 5 0 0.01BT_3881 4 1 0.23BT_3882 0 0 N/DBT_3883 1 0 0.07BT_3884 0 0 N/DBT_3885 94 109 1.16BT_3886 13 13 1.04BT_3887 0 0 N/DBT_3888 73 20 0.27BT_3889 308 362 1.18BT_3890 33 66 1.98BT_3891 4 5 1.36BT_3892 326 2 0.01BT_3893 330 530 1.61BT_3894 320 8 0.03BT_3895 575 1 0.00BT_3896 9 1 0.12BT_3897 55 134 2.46BT_3898 52 69 1.34

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BT_3899 854 453 0.53BT_3900 0 0 N/DBT_3901 1188 1114 0.94BT_3902 23 47 2.05BT_3903 60 39 0.65BT_3904 208 565 2.71BT_3905 144 199 1.38BT_3906 0 0 N/DBT_3907 0 0 1.15BT_3908 93 44 0.47BT_3909 0 0 0.42BT_3910 14 101 7.22BT_3911 6346 52833 8.33BT_3912 746 2 0.00BT_3913 75 98 1.29BT_3914 24 37 1.54BT_3915 0 0 0.51BT_3916 0 3 7.09BT_3917 0 0 0.17BT_3918 28 0 0.00BT_3919 51 0 0.01BT_3920 2 0 0.00BT_3921 0 0 0.83BT_3922 8 0 0.02BT_3923 3 0 0.00BT_3924 42 0 0.00BT_3925 0 0 N/DBT_3926 6 1 0.12BT_3927 0 0 N/DBT_3928 0 0 0.48BT_3929 0 1 N/DBT_3930 0 0 0.00BT_3931 0 1 N/DBT_3932 0 1 N/DBT_3933 326 0 0.00BT_3934 417 0 0.00BT_3935 444 0 0.00BT_3936 217 0 0.00BT_3937 247 234 0.95BT_3938 1 0 0.44BT_3939 3 0 0.13BT_3940 6 5 0.85BT_3941 0 0 N/DBT_3942 45 64 1.43

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BT_3943 0 0 N/DBT_3944 36 1 0.02BT_3945 0 0 N/DBT_3946 101 0 0.00BT_3947 110 1535 13.95BT_3948 45 0 0.01BT_3949 9 0 0.04BT_3950 13 0 0.02BT_3951 90 87 0.97BT_3952 74 594 7.98BT_3953 69 23 0.34BT_3954 7 1 0.07BT_3955 18 2 0.11BT_3956 15 10 0.68BT_3957 319 1130 3.54BT_3958 138 163 1.17BT_3959 50 175 3.52BT_3960 495 1251 2.53BT_3961 297 994 3.35BT_3962 294 119 0.41BT_3963 574 366 0.64BT_3964 228 198 0.87BT_3965 306 348 1.14BT_3966 0 0 N/DBT_3967 14 8 0.55BT_3968 0 0 N/DBT_3969 14 6 0.47BT_3970 45 31 0.68BT_3971 4 11 2.66BT_3972 32 38 1.20BT_3973 336 383 1.14BT_3974 0 0 0.99BT_3975 69 0 0.00BT_3976 100 240 2.39BT_3977 68 303 4.43BT_3978 49 1 0.03BT_3979 107 108 1.01BT_3980 540 96 0.18BT_3981 2489 0 0.00BT_3982 12 3 0.23BT_3983 248 104 0.42BT_3984 17 32 1.84BT_3985 59 25 0.42BT_3986 33 17 0.51

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BT_3987 57 19 0.33BT_3988 68 55 0.80BT_3989 6 6 1.07BT_3990 19 41 2.10BT_3991 130 218 1.68BT_3992 746 6 0.01BT_3993 14 6 0.45BT_3994 84 73 0.86BT_3995 0 1 N/DBT_3996 0 0 N/DBT_3997 0 0 N/DBT_3998 2 1 0.42BT_3999 480 51 0.11BT_4000 1 0 0.28BT_4001 0 0 1.08BT_4002 80 19 0.23BT_4003 0 0 N/DBT_4004 1 1 0.92BT_4005 58 62 1.07BT_4006 0 0 0.65BT_4007 2 0 0.14BT_4008 0 0 N/DBT_4009 2 3 1.34BT_4010 280 470 1.68BT_4011 0 0 N/DBT_4012 221 481 2.18BT_4013 43 75 1.72BT_4014 0 0 N/DBT_4015 0 0 N/DBT_4016 20 8 0.40BT_4017 0 0 N/DBT_4018 0 0 N/DBT_4019 0 0 N/DBT_4020 0 0 0.00BT_4021 0 0 1.09BT_4022 0 0 N/DBT_4023 1 0 0.12BT_4024 1 0 0.09BT_4025 0 0 N/DBT_4026 12 0 0.01BT_4027 0 0 N/DBT_4028 0 0 N/DBT_4029 0 0 0.00BT_4030 0 0 N/D

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BT_4031 0 0 N/DBT_4032 0 0 N/DBT_4033 0 0 N/DBT_4034 22 22 1.02BT_4035 0 0 N/DBT_4036 694 702 1.01BT_4037 19 25 1.34BT_4038 124 315 2.53BT_4039 158 229 1.45BT_4040 35 49 1.41BT_4041 1063 497 0.47BT_4042 146 280 1.91BT_4043 141 48 0.34BT_4044 0 0 N/DBT_4045 1351 1208 0.89BT_4046 0 0 N/DBT_4047 261 356 1.36BT_4048 524 7 0.01BT_4049 538 15 0.03BT_4050 238 386 1.62BT_4051 18 54 2.99BT_4052 60 33 0.55BT_4053 65 78 1.20BT_4054 6 97 16.93BT_4055 27 29 1.07BT_4056 54 5 0.10BT_4057 17 3 0.19BT_4058 536 515 0.96BT_4059 426 254 0.60BT_4060 594 372 0.63BT_4061 105 62 0.60BT_4062 141 330 2.33BT_4063 94 51 0.54BT_4064 465 338 0.73BT_4065 1053 955 0.91BT_4066 74 89 1.20BT_4067 12 10 0.87BT_4068 394 181 0.46BT_4069 69 112 1.61BT_4070 4 1 0.32BT_4071 0 0 N/DBT_4072 59 14 0.23BT_4073 87 10 0.11BT_4074 19 45 2.36

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BT_4075 0 0 N/DBT_4076 84 133 1.58BT_4077 25 6 0.25BT_4078 6 1 0.18BT_4079 50 45 0.90BT_4080 18 11 0.63BT_4081 18 16 0.89BT_4082 72 56 0.77BT_4083 44 23 0.52BT_4084 19 1 0.05BT_4085 76 46 0.61BT_4086 0 0 N/DBT_4087 46 11 0.24BT_4088 14 3 0.20BT_4089 25 26 1.03BT_4090 77 14 0.18BT_4091 72 34 0.47BT_4092 19 5 0.28BT_4093 77 4 0.06BT_4094 37 69 1.88BT_4095 0 1 N/DBT_4096 86 19 0.23BT_4097 0 3 5.88BT_4098 106 46 0.43BT_4099 1 0 0.32BT_4100 103 103 1.00BT_4101 0 0 1.07BT_4102 14 0 0.01BT_4103 415 7 0.02BT_4104 170 49 0.29BT_4105 14 10 0.70BT_4106 20 8 0.38BT_4107 4 5 1.50BT_4108 1 8 10.21BT_4109 1 12 13.91BT_4110 1 28 23.14BT_4111 89 169 1.89BT_4112 33 30 0.92BT_4113 74 15 0.20BT_4114 18 9 0.50BT_4115 36 25 0.69BT_4116 86 50 0.59BT_4117 1 3 1.98BT_4118 4 0 0.06

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BT_4119 5 11 2.25BT_4120 6 1 0.24BT_4121 24 28 1.14BT_4122 0 1 N/DBT_4123 3 1 0.18BT_4124 96 370 3.85BT_4125 0 6 13.68BT_4126 1478 0 0.00BT_4127 1018 0 0.00BT_4128 143 109 0.76BT_4129 467 223 0.48BT_4130 131 280 2.14BT_4131 410 449 1.09BT_4132 35 7 0.19BT_4133 71 28 0.39BT_4134 20 2 0.09BT_4135 21 12 0.60BT_4136 31 21 0.67BT_4137 59 36 0.60BT_4138 24 66 2.79BT_4139 23 14 0.60BT_4140 219 235 1.07BT_4141 0 0 N/DBT_4142 20 4 0.21BT_4143 29 2 0.06BT_4144 0 0 N/DBT_4145 20 6 0.30BT_4146 1 1 0.67BT_4147 1 0 0.11BT_4148 0 0 0.00BT_4149 0 0 N/DBT_4150 0 0 N/DBT_4151 16 99 6.00BT_4152 28 27 0.95BT_4153 129 85 0.66BT_4154 1 1 0.56BT_4155 114 68 0.60BT_4156 20 25 1.25BT_4157 44 72 1.62BT_4158 53 186 3.48BT_4159 0 1 N/DBT_4160 14 7 0.51BT_4161 0 0 N/DBT_4162 6 4 0.63

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BT_4163 29 23 0.80BT_4164 42 5 0.11BT_4165 20 13 0.62BT_4166 13 19 1.49BT_4167 36 37 1.01BT_4168 31 9 0.28BT_4169 15 17 1.14BT_4170 53 4 0.07BT_4171 0 0 N/DBT_4172 3 1 0.52BT_4173 29 1 0.03BT_4174 31 447 14.38BT_4175 73 4 0.06BT_4176 2 2 0.91BT_4177 2 0 0.06BT_4178 56 12 0.21BT_4179 29 13 0.43BT_4180 33 4 0.13BT_4181 46 9 0.20BT_4182 14 21 1.47BT_4183 58 68 1.17BT_4184 81 101 1.25BT_4185 54 1 0.02BT_4186 0 1 N/DBT_4187 59 1 0.02BT_4188 2396 629 0.26BT_4189 1333 1810 1.36BT_4190 30 50 1.67BT_4191 147 13 0.09BT_4192 0 0 0.93BT_4193 1173 2 0.00BT_4194 717 347 0.48BT_4195 0 0 N/DBT_4196 24 22 0.89BT_4197 28 11 0.38BT_4198 697 150 0.22BT_4199 102 64 0.63BT_4200 71 164 2.32BT_4201 73 107 1.47BT_4202 0 0 N/DBT_4203 17 8 0.45BT_4204 497 12 0.02BT_4205 64 0 0.00BT_4206 40 0 0.00

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BT_4207 31 7 0.21BT_4208 572 704 1.23BT_4209 1201 0 0.00BT_4210 1 0 0.27BT_4211 1 0 0.16BT_4212 185 225 1.21BT_4213 118 290 2.46BT_4214 102 186 1.83BT_4215 70 0 0.00BT_4216 62 0 0.01BT_4217 149 0 0.00BT_4218 44 0 0.00BT_4219 7 31 4.61BT_4220 775 808 1.04BT_4221 30 46 1.53BT_4222 25 52 2.10BT_4223 0 0 N/DBT_4224 135 239 1.77BT_4225 52 70 1.35BT_4226 1 3 4.01BT_4227 0 0 0.84BT_4228 0 0 N/DBT_4229 25 24 0.98BT_4230 1 17 22.53BT_4231 80 65 0.81BT_4232 0 1 2.31BT_4233 14 22 1.53BT_4234 0 0 0.00BT_4235 31 32 1.05BT_4236 18 20 1.16BT_4237 44 89 2.00BT_4238 40 11 0.26BT_4239 55 20 0.37BT_4240 256 157 0.61BT_4241 349 159 0.45BT_4242 76 9 0.12BT_4243 607 211 0.35BT_4244 40 2 0.06BT_4245 18 16 0.93BT_4246 24 5 0.23BT_4247 33 39 1.19BT_4248 238 57 0.24BT_4249 119 35 0.29BT_4250 20 12 0.59

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BT_4251 44 5 0.11BT_4252 27 82 3.07BT_4253 0 0 N/DBT_4254 0 0 0.00BT_4255 2 0 0.00BT_4256 0 0 N/DBT_4257 135 266 1.97BT_4258 130 113 0.87BT_4259 247 4 0.02BT_4260 35 0 0.00BT_4261 152 0 0.00BT_4262 597 1 0.00BT_4263 0 0 N/DBT_4264 58 100 1.72BT_4265 1096 0 0.00BT_4266 0 1 2.10BT_4267 39 5 0.12BT_4268 10 1 0.07BT_4269 16 2 0.11BT_4270 149 19 0.13BT_4271 0 0 N/DBT_4272 24 9 0.39BT_4273 49 10 0.21BT_4274 0 0 0.18BT_4275 4 1 0.38BT_4276 0 0 N/DBT_4277 0 0 N/DBT_4278 0 0 N/DBT_4279 12 0 0.03BT_4280 31 18 0.60BT_4281 62 13 0.21BT_4282 18 2 0.14BT_4283 58 5 0.09BT_4284 7 6 0.76BT_4285 30 3 0.11BT_4286 0 0 N/DBT_4287 3 0 0.15BT_4288 20 13 0.63BT_4289 3 6 1.74BT_4290 0 0 N/DBT_4291 0 0 N/DBT_4292 6 24 3.89BT_4293 2 13 7.96BT_4294 0 0 N/D

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BT_4295 115 54 0.47BT_4296 30 57 1.87BT_4297 67 31 0.46BT_4298 74 51 0.70BT_4299 8 14 1.83BT_4300 187 9 0.05BT_4301 218 1170 5.35BT_4302 0 0 0.00BT_4303 872 0 0.00BT_4304 1265 1 0.00BT_4305 532 1 0.00BT_4306 559 0 0.00BT_4307 2 0 0.07BT_4308 0 0 N/DBT_4309 0 0 N/DBT_4310 1042 1039 1.00BT_4311 59 65 1.11BT_4312 0 0 N/DBT_4313 0 0 N/DBT_4314 1 0 0.12BT_4315 0 5 N/DBT_4316 188 226 1.20BT_4317 17 18 1.02BT_4318 41 279 6.80BT_4319 112 172 1.54BT_4320 866 1135 1.31BT_4321 0 0 N/DBT_4322 0 0 N/DBT_4323 61 0 0.00BT_4324 22 22 0.97BT_4325 2 35 14.74BT_4326 102 138 1.36BT_4327 822 1741 2.12BT_4328 59 44 0.74BT_4329 356 253 0.71BT_4330 273 106 0.39BT_4331 489 149 0.30BT_4332 283 48 0.17BT_4333 287 85 0.30BT_4334 1 1 0.98BT_4335 0 0 N/DBT_4336 67 0 0.01BT_4337 180 388 2.16BT_4338 82 0 0.00

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BT_4339 1732 567 0.33BT_4340 6 2 0.32BT_4341 23 3 0.12BT_4342 28 87 3.09BT_4343 0 0 0.71BT_4344 33 18 0.54BT_4345 1 0 0.07BT_4346 132 153 1.16BT_4347 3 7 2.05BT_4348 239 36 0.15BT_4349 422 75 0.18BT_4350 22 10 0.44BT_4351 17 49 2.85BT_4352 13 22 1.68BT_4353 0 0 N/DBT_4354 10 4 0.41BT_4355 15 17 1.10BT_4356 0 0 N/DBT_4357 37 4 0.11BT_4358 7 8 1.18BT_4359 1 7 5.48BT_4360 1239 3556 2.87BT_4361 194 248 1.28BT_4362 1 1 0.88BT_4363 89 2 0.02BT_4364 25 0 0.00BT_4365 1 0 0.00BT_4366 0 0 N/DBT_4367 1 0 0.21BT_4368 0 0 N/DBT_4369 21 1 0.06BT_4370 337 504 1.49BT_4371 1462 1 0.00BT_4372 0 0 N/DBT_4373 1 0 0.40BT_4374 2 1 0.50BT_4375 0 1 N/DBT_4376 0 0 N/DBT_4377 22 0 0.01BT_4378 510 885 1.73BT_4379 601 309 0.51BT_4380 45 59 1.31BT_4381 9 34 3.77BT_4382 313 1 0.00

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BT_4383 74 103 1.38BT_4384 0 0 N/DBT_4385 100 30 0.30BT_4386 0 0 N/DBT_4387 0 0 N/DBT_4388 23 1 0.03BT_4389 203 368 1.82BT_4390 156 247 1.58BT_4391 90 305 3.37BT_4392 0 0 N/DBT_4393 1 7 9.46BT_4394 34 39 1.15BT_4395 63 144 2.27BT_4396 2 16 6.74BT_4397 1 1 1.16BT_4398 31 8 0.27BT_4399 31 123 3.96BT_4400 6 31 5.07BT_4401 0 0 N/DBT_4402 17 25 1.44BT_4403 806 459 0.57BT_4404 141 65 0.46BT_4405 26 2 0.09BT_4406 27 2 0.06BT_4407 26 0 0.01BT_4408 131 0 0.00BT_4409 0 0 N/DBT_4410 0 1 N/DBT_4411 2 12 5.42BT_4412 89 101 1.13BT_4413 111 175 1.58BT_4414 0 0 N/DBT_4415 1 3 3.47BT_4416 19 8 0.42BT_4417 7 1 0.09BT_4418 0 0 N/DBT_4419 0 0 N/DBT_4420 86 112 1.31BT_4421 1 0 0.00BT_4422 0 0 0.26BT_4423 19 1 0.07BT_4424 0 0 N/DBT_4425 0 0 N/DBT_4426 47 8 0.17

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BT_4427 38 10 0.26BT_4428 0 0 N/DBT_4429 9 24 2.70BT_4430 12 1 0.08BT_4431 19 26 1.38BT_4432 26 6 0.23BT_4433 88 1454 16.51BT_4434 0 0 N/DBT_4435 20 12 0.59BT_4436 30 7 0.24BT_4437 11 14 1.26BT_4438 6 26 4.66BT_4439 0 0 N/DBT_4440 118 224 1.91BT_4441 1 0 0.51BT_4442 6 12 1.83BT_4443 33 53 1.61BT_4444 2 1 0.36BT_4445 89 178 2.00BT_4446 7 5 0.73BT_4447 2 0 0.17BT_4448 4 2 0.47BT_4449 1 1 0.74BT_4450 1 0 0.00BT_4451 30 46 1.56BT_4452 1 0 0.35BT_4453 23 18 0.79BT_4454 36 51 1.41BT_4455 27 27 1.00BT_4456 121 121 1.00BT_4457 58 79 1.37BT_4458 22 67 3.12BT_4459 55 32 0.58BT_4460 71 30 0.42BT_4461 14 1 0.06BT_4462 24 16 0.67BT_4463 24 78 3.24BT_4464 2 3 1.23BT_4465 2 0 0.24BT_4466 4 0 0.03BT_4467 380 193 0.51BT_4468 32 90 2.82BT_4469 1 6 7.16BT_4470 31 71 2.28

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BT_4471 44 1 0.02BT_4472 101 112 1.12BT_4473 10 73 7.02BT_4474 808 753 0.93BT_4475 17 1 0.05BT_4476 26 86 3.36BT_4477 18 4 0.24BT_4478 422 256 0.61BT_4479 11 0 0.02BT_4480 196 128 0.65BT_4481 19 12 0.64BT_4482 20 48 2.41BT_4483 0 0 N/DBT_4484 26 0 0.00BT_4485 9 11 1.24BT_4486 4 5 1.22BT_4487 42 145 3.42BT_4488 73 115 1.57BT_4489 58 114 1.95BT_4490 0 1 N/DBT_4491 17 9 0.50BT_4492 89 87 0.97BT_4493 3 3 1.15BT_4494 13 15 1.16BT_4495 248 190 0.77BT_4496 15 31 2.04BT_4497 8 4 0.52BT_4498 1 0 0.13BT_4499 80 578 7.21BT_4500 52 28 0.53BT_4501 0 1 1.43BT_4502 0 0 N/DBT_4503 146 278 1.91BT_4504 0 0 N/DBT_4505 5 45 8.66BT_4506 225 765 3.40BT_4507 67 127 1.91BT_4508 151 152 1.01BT_4509 66 211 3.20BT_4510 14 4 0.27BT_4511 0 5 N/DBT_4512 0 3 7.33BT_4513 28 7 0.24BT_4514 15 3 0.24

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BT_4515 32 29 0.91BT_4516 240 329 1.37BT_4517 202 504 2.50BT_4518 89 740 8.29BT_4519 93 163 1.76BT_4520 87 148 1.69BT_4521 1 0 0.00BT_4522 0 0 0.00BT_4523 44 0 0.00BT_4524 0 0 0.55BT_4525 0 0 N/DBT_4526 0 0 N/DBT_4527 6 40 6.25BT_4528 54 37 0.68BT_4529 78 219 2.82BT_4530 134 649 4.83BT_4531 60 131 2.20BT_4532 21 68 3.33BT_4533 90 143 1.58BT_4534 142 166 1.17BT_4535 562 911 1.62BT_4536 109 249 2.29BT_4537 556 760 1.37BT_4538 432 748 1.73BT_4539 106 210 1.98BT_4540 161 324 2.01BT_4541 0 0 N/DBT_4542 0 0 N/DBT_4543 10 27 2.78BT_4544 28 1 0.02BT_4545 21 13 0.64BT_4546 0 0 N/DBT_4547 0 0 N/DBT_4548 17 1 0.04BT_4549 9 3 0.29BT_4550 65 8 0.13BT_4551 210 10 0.05BT_4552 2 1 0.33BT_4553 1 3 2.10BT_4554 398 397 1.00BT_4555 442 349 0.79BT_4556 52 77 1.46BT_4557 537 3 0.00BT_4558 19 46 2.44

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BT_4559 17 30 1.72BT_4560 12 0 0.02BT_4561 5 0 0.00BT_4562 34 0 0.00BT_4563 80 0 0.00BT_4564 20 0 0.01BT_4565 25 0 0.01BT_4566 10 4 0.42BT_4567 0 1 N/DBT_4568 56 11 0.20BT_4569 763 2 0.00BT_4570 158 1 0.01BT_4571 0 0 N/DBT_4572 1288 305 0.24BT_4573 28 1 0.04BT_4574 14 59 4.26BT_4575 1 0 0.08BT_4576 10 7 0.67BT_4577 0 0 N/DBT_4578 0 0 N/DBT_4579 0 0 N/DBT_4580 0 0 N/DBT_4581 6 2 0.36BT_4582 1467 1897 1.29BT_4583 1341 131 0.10BT_4584 403 137 0.34BT_4585 30 42 1.41BT_4586 49 34 0.70BT_4587 129 242 1.88BT_4588 0 0 N/DBT_4589 0 0 N/DBT_4590 213 154 0.72BT_4591 7 1 0.08BT_4592 0 0 N/DBT_4593 0 1 N/DBT_4594 0 0 N/DBT_4595 784 174 0.22BT_4596 199 2119 10.66BT_4597 60 100 1.67BT_4598 15 4 0.29BT_4599 131 21 0.16BT_4600 2 1 0.37BT_4601 116 15 0.13BT_4602 3 2 0.57

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BT_4603 1 0 0.17BT_4604 50 7 0.13BT_4605 42 33 0.78BT_4606 18 3 0.18BT_4607 4 20 5.26BT_4608 11 41 3.64BT_4609 514 1149 2.23BT_4610 910 9 0.01BT_4611 350 3 0.01BT_4612 849 11 0.01BT_4613 56 8 0.15BT_4614 2292 730 0.32BT_4615 2 1 0.50BT_4616 0 0 0.30BT_4617 0 0 0.39BT_4618 0 0 N/DBT_4619 32 6 0.19BT_4620 4 2 0.44BT_4621 0 0 N/DBT_4622 216 59 0.27BT_4623 90 72 0.80BT_4624 0 0 N/DBT_4625 34 75 2.19BT_4626 23 139 6.16BT_4627 125 119 0.96BT_4628 43 157 3.65BT_4629 70 23 0.33BT_4630 83 311 3.73BT_4631 66 4 0.06BT_4632 13 3 0.25BT_4633 66 26 0.39BT_4634 102 18 0.17BT_4635 24 273 11.34BT_4636 21 47 2.18BT_4637 0 0 N/DBT_4638 0 0 0.35BT_4639 0 0 N/DBT_4640 261 337 1.29BT_4641 0 3 6.45BT_4642 39 0 0.01BT_4643 0 0 N/DBT_4644 127 0 0.00BT_4645 46 17 0.37BT_4646 29 15 0.52

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BT_4647 21 0 0.01BT_4648 493 80 0.16BT_4649 161 1 0.01BT_4650 1 6 7.49BT_4651 129 272 2.11BT_4652 51 54 1.08BT_4653 9 6 0.63BT_4654 7 6 0.95BT_4655 22 66 2.96BT_4656 127 45 0.35BT_4657 21 2 0.09BT_4658 55 1 0.02BT_4659 61 1 0.01BT_4660 139 117 0.85BT_4661 33 1 0.02BT_4662 19 25 1.32BT_4663 426 658 1.54BT_4664 1011 1596 1.58BT_4665 24 26 1.08BT_4666 0 0 N/DBT_4667 15 2 0.11BT_4668 41 0 0.00BT_4669 0 0 N/DBT_4670 61 13 0.21BT_4671 43 2 0.04BT_4672 0 0 N/DBT_4673 92 21 0.22BT_4674 393 511 1.30BT_4675 1 1 0.49BT_4676 6 0 0.05BT_4677 1 6 7.48BT_4678 262 223 0.85BT_4679 25 31 1.24BT_4680 25 27 1.07BT_4681 44 86 1.97BT_4682 255 371 1.45BT_4683 49 25 0.50BT_4684 14 8 0.56BT_4685 0 2 4.13BT_4686 0 3 N/DBT_4687 0 0 0.45BT_4688 1 0 0.47BT_4689 53 4 0.08BT_4690 2 1 0.29

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BT_4691 9 12 1.36BT_4692 167 106 0.64BT_4693 15 8 0.54BT_4694 37 35 0.94BT_4695 2 1 0.38BT_4696 6 17 3.12BT_4697 31 11 0.34BT_4698 20 69 3.43BT_4699 1485 8 0.01BT_4700 293 2 0.01BT_4701 1033 9 0.01BT_4702 391 311 0.80BT_4703 236 180 0.76BT_4704 114 123 1.07BT_4705 2 24 14.70BT_4706 133 23 0.17BT_4707 83 32 0.39BT_4708 18 0 0.02BT_4709 0 0 N/DBT_4710 15 1 0.09BT_4711 2 10 4.96BT_4712 1 1 0.65BT_4713 49 48 0.97BT_4714 2 1 0.45BT_4715 0 0 N/DBT_4716 86 54 0.63BT_4717 27 19 0.70BT_4718 36 85 2.36BT_4719 54 12 0.22BT_4720 3 2 0.69BT_4721 1107 15 0.01BT_4722 18 12 0.67BT_4723 10 0 0.01BT_4724 17 22 1.30BT_4725 15 14 0.88BT_4726 2 1 0.33BT_4727 0 0 N/DBT_4728 41 5 0.11BT_4729 0 0 N/DBT_4730 11 2 0.19BT_4731 1 1 0.87BT_4732 987 789 0.80BT_4733 86 13 0.15BT_4734 24 6 0.23

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BT_4735 0 0 N/DBT_4736 71 104 1.46BT_4737 85 177 2.07BT_4738 2177 4510 2.07BT_4739 7 11 1.66BT_4740 0 0 N/DBT_4741 8 63 8.02BT_4742 0 0 N/DBT_4743 0 0 0.13BT_4744 38 3 0.08BT_4745 19 32 1.65BT_4746 1 1 1.38BT_4747 0 0 N/DBT_4748 1 0 0.00BT_4749 5 27 5.09BT_4750 0 0 N/DBT_4751 3 22 6.92BT_4752 1 0 0.22BT_4753 135 139 1.03BT_4754 131 194 1.48BT_4755 343 406 1.18BT_4756 88 167 1.90BT_4757 62 74 1.20BT_4758 1 0 0.40BT_4759 0 0 N/DBT_4760 0 0 N/DBT_4761 0 0 N/DBT_4762 7 0 0.01BT_4763 0 0 N/DBT_4764 33 10 0.29BT_4765 1 0 0.50BT_4766 0 0 0.23BT_4767 2 0 0.05BT_4768 0 0 N/DBT_4769 2 0 0.12BT_4770 8 21 2.80BT_4771 0 0 N/DBT_4772 0 0 N/DBT_4773 0 0 0.00BT_4774 0 7 15.50BT_4775 0 0 N/DBT_4776 1 0 0.00BT_4777 0 0 N/DBT_4778 1 1 0.61

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BT_4779 0 0 N/DBT_4780 0 0 0.62

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Barcode (%)96.895.395.693.895.997.0

Barcode Reads Barcode (%) Transposon Reads Transposon (%) Scale factor926504 6.1 891293 96.2 1.5

1625329 10.7 1584361 97.5 0.91322788 8.7 1196381 90.4 0.91573095 10.3 1504899 95.7 0.71530733 10.0 1469627 96.0 0.71864652 12.2 1767144 94.8 0.61304444 8.6 1253913 96.1 0.9803470 5.3 767544 95.5 1.4

1166079 7.6 1119661 96.0 1.01562975 10.2 1505431 96.3 0.71565435 12.0 1471786 94.0 0.7984703 7.6 928604 94.3 1.2

1023773 7.9 970347 94.8 1.11363138 10.5 1198315 87.9 0.91425416 10.9 1347032 94.5 0.8963681 7.4 919556 95.4 1.2

1118731 8.6 1070195 95.7 1.01577636 12.1 1491934 94.6 0.71463596 11.2 1403847 95.9 0.8929339 7.1 879553 94.6 1.2

2326020 13.5 1969789 84.7 0.5877470 5.1 836299 95.3 1.3791821 4.6 746655 94.3 1.4

2572267 14.9 2428316 94.4 0.41475546 8.6 1396073 94.6 0.81781020 10.3 1714760 96.3 0.61703408 9.9 1521970 89.3 0.7291241 1.7 277710 95.4 3.8

1854668 10.8 1775047 95.7 0.61521539 8.8 1436491 94.4 0.7

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1291514 7.5 1234652 95.6 0.9618286 3.7 586966 94.9 1.8

1753962 10.6 1678154 95.7 0.61403214 8.5 1359503 96.9 0.81934645 11.7 1813934 93.8 0.6823764 5.0 781670 94.9 1.3

1845768 11.1 1760593 95.4 0.61157817 7.0 1075958 92.9 1.01790584 10.8 1670977 93.3 0.61761093 10.6 1697957 96.4 0.61108516 6.7 1059641 95.6 1.01336869 8.1 1271265 95.1 0.81282734 5.0 N/A N/A N/A727610 2.7 N/A N/A N/A

1505261 5.6 N/A N/A N/A

q-value Annotation0.0051 putative lipoprotein0.0029 hypothetical protein0.0676 hypothetical protein0.1499 hypothetical protein0.2419 30S ribosomal protein S170.0000 hypothetical protein0.0780 hypothetical protein0.1898 GCN5-related N-acetyltransferase0.2334 phosphate-binding periplasmic protein precursor, putative ABC transporter0.0670 hypothetical protein0.2763 hypothetical protein0.0104 putative lipoprotein

N/D hypothetical protein0.2447 rteA, two-component system histidine kinase, with response regulator receiver domain0.2823 rteB, two-component system response regulator0.1707 conserved hypothetical protein0.2128 conserved hypothetical protein0.1195 hypothetical protein0.0362 conserved hypothetical protein0.0531 conserved hypothetical protein0.2230 hypothetical protein0.1937 Putative DNA binding protein0.0000 transposase0.0533 transposase

for survival in the intestines of mice harboring the 15-member model human gut microbiota.

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0.0541 putative transposase0.0041 putative transposase0.1042 putative transposase0.0077 alkaline phosphatase0.0890 SusC homolog0.0843 SusD homolog0.0002 Polymerase and histidinol phosphatase0.3049 hypothetical protein0.1055 hypothetical protein0.1585 putative transposase0.0308 hypothetical protein0.1638 integrase0.0019 putative transcriptional regulatory protein0.0004 hypothetical protein0.0085 conserved hypothetical protein0.0386 putative transmembrane protein0.2823 F420H2:quinone oxidoreductase0.0023 nitroreductase-like protein0.1283 putative glycosyltransferase0.1319 glycoside transferase family 20.2479 putative polysaccharide biosynthesis protein0.2147 glycoside transferase family 20.1922 glycoside transferase family 20.2600 hypothetical protein

N/D putative glycosyltransferase0.1324 glycoside transferase family 20.0000 glycoside transferase family 20.0000 hypothetical protein0.0226 glycoside transferase family 40.0044 glycoside transferase family 40.0110 glycoside transferase family 40.0667 putative glycosyltransferase0.1713 hypothetical protein0.2938 hypothetical protein

N/D conserved hypothetical protein0.0272 putative polysaccharide export protein0.1427 putative tyrosine-protein kinase ptk

N/D hypothetical proteinN/D hypothetical protein

0.2130 hypothetical protein0.0781 alpha-galactosidase precursor0.0758 major outer membrane protein OmpA0.2974 hypothetical protein0.0584 hypothetical protein

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0.0721 transposase0.0781 transposase0.1743 hypothetical protein0.0099 putative ABC transporter, ATP-binding protein0.0233 putative ABC transporter, ATP-binding protein0.1844 hypothetical protein0.0306 conserved hypothetical protein0.0290 transposase0.0797 conserved hypothetical protein0.0389 putative DNA repair protein0.0681 putative anti-restriction protein0.2451 conserved hypothetical protein0.0760 conserved hypothetical protein0.0768 conserved hypothetical protein0.0031 conserved hypothetical protein

N/D conserved protein found in conjugate transposon0.0758 conserved protein found in conjugate transposon0.2438 conserved protein found in conjugate transposon0.0000 conserved protein found in conjugate transposon0.1522 conserved protein found in conjugate transposon0.2260 conserved protein found in conjugate transposon0.2980 conserved protein found in conjugate transposon0.2234 conserved protein found in conjugate transposon

N/D conserved protein found in conjugate transposon0.1188 conserved protein found in conjugate transposon0.3182 conserved protein found in conjugate transposon0.0797 conserved protein found in conjugate transposon0.2220 conserved hypothetical protein0.1351 conserved protein found in conjugate transposon0.0404 conserved protein found in conjugate transposon0.2161 hypothetical protein0.0765 conserved hypothetical protein0.1283 putative mobilisation protein0.0212 putative transmembrane mobilisation protein0.0797 conserved hypothetical protein

N/D hypothetical protein0.2156 DNA topoisomerase I (Omega-protein)0.0770 riboflavin biosynthesis protein RibD-like protein0.0676 Putative DNA binding protein0.0000 conserved hypothetical protein0.0649 Putative DNA binding protein0.2474 putative regulatory protein0.2837 hypothetical protein0.1940 putative permease

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N/D hypothetical protein0.0291 putative symporter, arsenic resistance membrane protein0.0760 arsenate reductase0.1769 arsenical pump-driving ATPase0.0923 arsenical resistance operon trans-acting repressor0.0403 putative cytochrome c biogenesis protein0.1365 hypothetical protein0.0770 redox-active disulfide protein 2-like protein0.2722 transcriptional regulator, ArsR family0.0000 3-oxoacyl-[acyl-carrier-protein] synthase III0.2429 NADH-ubiquinone oxidoreductase subunit0.1102 NADH:ubiquinone oxidoreductase subunit0.1878 NADH:ubiquinone oxidoreductase subunit0.2672 Six-hairpin glycosidase0.3158 putative transmembrane protein0.0202 hypothetical protein0.2612 mannonate dehydratase0.0663 putative oxidoreductase

N/D putative transposase0.0448 alpha-glucosidase, putative0.0781 putative sugar phosphate isomerase0.2701 conserved hypothetical protein0.0001 conserved hypothetical protein0.1801 hypothetical protein0.1428 Acetyl-CoA carboxylase-like protein0.2481 transcriptional regulator0.0647 RNA polymerase ECF-type sigma factor0.2750 SusC homolog0.3098 SusD homolog0.1491 alpha-fucosidase-like protein0.2836 putative transmembrane protein

N/D putative beta-xylosidase0.0991 putative beta-xylosidase0.0000 unsaturated glucuronyl hydrolase0.1713 conserved hypothetical protein0.1695 putative hemolysin0.0515 peptidase0.0000 putative ferric aerobactin receptor0.0410 conserved hypothetical protein0.0293 acetyl esterase (acetylxylosidase)0.0705 conserved hypothetical protein0.2199 putative periplasmic protease0.0009 putative tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase0.2329 transcriptional regulator

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0.0584 conserved hypothetical protein0.1029 Na(+)/H(+) antiporter0.0781 conserved hypothetical protein0.0026 conserved hypothetical protein0.2465 putative permease0.2664 penicillin-binding protein 1C (PBP-1c)0.2838 putative outer membrane protein0.0303 putative outer membrane protein, alpha-2-macroglobulin-like protein0.0183 peptidyl-prolyl cis-trans isomerase0.0210 putative thiol-disulfide isomerase0.0448 conserved hypothetical protein0.1827 nucleotidyltransferase family protein0.0575 putative endonuclease/exonuclease/phosphatase0.1940 putative conserved membrane protein0.0320 Peptidase M-like protein0.2001 hypothetical protein0.0000 conserved hypothetical protein0.0000 conserved hypothetical protein0.1940 conserved hypothetical protein0.1009 conserved hypothetical protein0.0000 conserved hypothetical protein0.0001 conserved hypothetical protein0.0000 SsrA-binding protein0.0015 5-methyltetrahydrofolate-homocysteine methyltransferase0.0770 putative NADH dehydrogenase/NAD(P)H nitroreductase0.0196 osmo-regulated proline transporter (Na+/proline symporter)0.0233 glycoside hydrolase family 230.3080 uridine kinase (uridine monophosphokinase)0.0000 stress responsive A/B barrel domain-like protein0.0000 thiol:disulfide interchange protein dsbD precursor0.0770 possible Pirin family protein0.0095 RNA polymerase ECF-type sigma factor0.1884 conserved hypothetical protein, putative anti-sigma factor0.2144 SusC homolog0.1723 SusD homolog0.0708 cell surface protein0.0002 sugar phosphate isomerase / epimerase-like protein0.1205 Multicopper oxidase, copper-binding0.0467 glycerophosphoryl diester phosphodiesterase0.3148 putative hexose phosphate transport protein0.2518 conserved hypothetical protein0.2481 putative lipoprotein0.0492 Thioesterase superfamily like protein0.2582 ATP phosphoribosyltransferase

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0.0327 histidinol dehydrogenase0.0516 histidinol-phosphate aminotransferase0.0293 histidine biosynthesis bifunctional protein hisB0.0754 protein tyrosine/serine phosphatase0.0296 glutamine-dependent NAD+ synthetase0.0496 SusC homolog0.0283 SusD homolog0.1018 hypothetical protein0.3146 hypothetical protein0.0304 leucine-rich repeat protein0.0762 Leucine-rich repeat protein0.0205 protease0.1050 conserved hypothetical protein0.0614 hypothetical protein0.3099 iron uptake regulatory protein0.3097 putative rubrerythrin0.1478 nitroreductase-like protein0.0120 thioredoxin (TRX)0.0000 thioredoxin C-20.1940 hypothetical protein0.1967 putative ATPase0.0000 putative two-component system sensor kinase0.0982 two-component system response regulator0.0775 Lipocalin-like protein0.0081 hypothetical protein0.0031 hypothetical protein0.0386 conserved hypothetical protein0.1728 putative protein involved in recombination0.0043 conserved hypothetical protein0.0286 Winged helix repressor DNA-binding0.2990 excisionase0.0663 putative protein involved in transposition0.1940 integrase0.1113 putative transposase0.0033 UDP-glucuronosyl/UDP-glucosyltrasferase0.0314 conserved hypothetical protein0.2515 Peptidase, trypsin-like serine and cysteine0.0002 transcriptional regulator0.2747 thiol:disulfide interchange protein0.0261 TPR-repeat-containing protein0.2082 conserved hypothetical protein0.0067 putative polysaccharide deacetylase0.0006 putative 1-acyl-sn-glycerol-3-phosphate acyltransferase0.1125 putative exonuclease

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0.1018 ATP-dependent exonuclease sbcC0.0724 putative integral membrane protein, with calcineurin-like phosphoesterase domain0.0000 conserved hypothetical protein0.2595 RNA polymerase ECF-type sigma factor0.0000 5-methyltetrahydrofolate--homocysteine methyltransferase or methionine synthase0.0000 dihydroorotase (DHOase)0.0676 dolichol-phosphate mannosyltransferase0.0127 transcription-repair coupling factor0.0007 hypothetical protein0.0014 putative Fe-S oxidoreductase0.0548 conserved hypothetical protein0.0463 conserved hypothetical protein0.1311 xanthan lyase0.0000 glucosamine-6-phosphate isomerase0.0205 putative amidohydrolase0.2103 acyltransferase family protein0.0021 conserved hypothetical protein0.0084 conserved hypothetical protein0.0000 Six-hairpin glycosidase0.0080 glycoside hydrolase family 430.1465 beta-glucanase precursor0.0001 Galactose-binding-like protein0.0063 two-component system sensor histidine kinase/response regulator, hybrid (one component system)0.0930 SusC homolog0.0000 SusD homolog0.2137 hypothetical protein0.1900 hypothetical protein0.2582 SusC homolog0.0113 SusD homolog0.0270 hypothetical protein0.1995 conserved hypothetical protein0.0006 Concanavalin A-like lectin/glucanase0.0488 Coagulation factor 5/8 type, C-terminal0.1011 Concanavalin A-like lectin/glucanase0.2491 hypothetical protein

N/D transposase for insertion sequence element ISRM30.0891 putative DNA-binding protein0.0032 putative helicase

N/D hypothetical protein0.2547 putative peptidoglycan binding protein (LPXTG motif)0.0530 putative tolQ-type transport protein0.0797 Biopolymer transport protein ExbD/TolR0.1689 putative biopolymer transmembrane protein0.0012 conserved hypothetical protein

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0.0310 TonB-dependent receptor domain protein0.2189 beta-galactosidase precursor0.0012 integrase0.2779 conserved hypothetical protein0.1061 conserved hypothetical protein0.1251 Carboxypeptidase regulatory region0.2212 ABC transporter ATP-binding protein0.2676 putative xanthan lyase XalB precursor0.0263 putative outer membrane lipoprotein silC precursor0.0474 cation efflux system protein (outer membrane protein)0.0007 cation efflux system (AcrB/AcrD/AcrF family)0.1151 cation efflux system (AcrB/AcrD/AcrF family)0.0028 ATP-binding transport protein natA (Na+ ABC transporter)0.2302 hypothetical protein0.0118 putative patatin-like phospholipase0.0004 acriflavine resistance protein A precursor0.1473 putative aminoglycoside efflux pump (Acriflavine resistance protein)0.1142 outer membrane protein oprM precursor0.0625 phosphofructokinase0.0004 glycoside hydrolase family 250.0993 Dihydrolipoamide dehydrogenase0.1765 lipoate-protein ligase A0.0339 lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex0.2285 2-oxoisovalerate dehydrogenase beta subunit0.0783 flavodoxin0.2132 ribosomal protein L11 methyltransferase0.0002 conserved hypothetical protein0.2230 putative hemin receptor0.2422 SusC homolog0.0233 SusD homolog0.0765 conserved hypothetical protein0.1480 hypothetical protein0.3140 cytidine/deoxycytidylate deaminase0.0037 putative oxidoreductase0.0010 conserved hypothetical protein0.0000 conserved hypothetical protein0.0000 conserved hypothetical protein

N/D putative RNA polymerase ECF-type sigma factor0.0132 glutamine ABC transporter, periplasmic glutamine-binding protein (glnH)0.0510 conserved hypothetical protein0.0001 ketoisovalerate oxidoreductase subunit vorA0.0000 ketoisovalerate oxidoreductase subunit vorA0.0000 ketoisovalerate oxidoreductase subunit vorB0.0589 2-oxoisovalerate oxidoreductase beta subunit

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0.0013 4Fe-4S ferredoxin, iron-sulfur binding protein0.0011 conserved hypothetical protein0.1882 putative ATPase0.1375 conserved hypothetical protein0.0441 conserved hypothetical protein0.0463 Pectin lyase fold/virulence factor0.1972 alpha-glucosidase0.1153 trimethylamine corrinoid protein 2 (TCP 2)0.1972 Na+/glucose cotransporter0.0001 putative 5-methyltetrahydrofolate-homocystein methyltransferase0.0464 methylcobamide:CoM methyltransferase mtbA0.0502 hypothetical protein0.1296 hypothetical protein0.0001 ribose 5-phosphate isomerase B0.0000 transketolase0.0179 alpha-L-arabinofuranosidase0.0498 Acetyl-CoA carboxylase, biotin carboxylase0.0000 xylulose kinase (xylulokinase)0.0000 L-arabinose isomerase0.2580 conserved hypothetical protein0.0207 putative sugar epimerase/aldolase0.0000 NUDIX family hydrolase0.0000 Na+/glucose cotransporter0.0000 aldose 1-epimerase precursor

N/D hypothetical proteinN/D transposaseN/D hypothetical protein

0.1987 putative arabinan endo-1,5-alpha-L-arabinosidase0.2559 SusD homolog0.2695 SusC homolog0.0003 SusD homolog0.0003 SusC homolog0.0466 Concanavalin A-like lectin/glucanase0.2681 two-component system sensor histidine kinase/response regulator, hybrid (one component system)0.0000 putative endo-arabinase0.1019 alpha-L-arabinofuranosidase A precursor0.0680 endo-1,4-beta-xylanase D precursor0.0000 galactokinase0.0100 glucose/galactose transporter0.0275 aldose 1-epimerase precursor0.0000 mannose-6-phosphate isomerase0.0094 conserved hypothetical protein0.0452 integrase0.0001 putative transcriptional regulator

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0.1756 conserved hypothetical protein0.0457 capsular polysaccharide biosynthesis protein capD0.0358 UDP-glucose 6-dehydrogenase0.2357 nucleotide sugar epimerase0.3067 capsular polysaccharide biosynthesis protein capD0.1414 capsular polysaccharide biosynthesis protein Cps4K0.2733 putative UDP-N-acetylglucosamine 2-epimerase0.1205 hypothetical protein0.2223 conserved hypothetical protein0.0748 putative F420H2-dehydrogenase0.1977 NADH dehydrogenase subunit 20.2473 galactoside O-acetyltransferase0.1437 putative galactoside acetyltransferase0.2236 putative O-antigen export protein0.1407 putative protein involved in capsular polysaccharide biosynthesis0.3059 lipopolysaccharide biosynthesis RfbU-related protein0.0006 serine acetyltransferase0.1176 capsular polysaccharide biosynthesis glycosyltransferase0.0420 hypothetical protein0.0555 putative UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase0.0781 conserved hypothetical protein0.0715 polysaccharide export outer membrane protein0.0843 tyrosine-protein kinase ptk involved in exopolysaccharide biosynthesis0.1021 putative tyrosine-protein kinase in capsular polysaccharide biosynthesis region0.0780 hypothetical protein0.0680 hypothetical protein

N/D putative DNA binding protein0.0647 hypothetical protein

N/D hypothetical protein0.1039 conserved hypothetical protein0.1602 conserved hypothetical protein0.1214 conserved hypothetical protein0.2664 putative short-chain dehydrogenase0.1511 Sporulation related0.0664 CysQ, sulfite synthesis pathway protein0.2376 putative Na+/sulfate symporter0.0233 putative adenylylsulfate kinase0.2602 sulfate adenylyltransferase subunit 20.2782 sulfate adenylyltransferase subunit 1/adenylylsulfate kinase0.0381 possible sulfotransferase0.0663 conserved hypothetical protein0.0000 outer membrane porin F precursor0.1940 putative endonuclease0.0716 peptide deformylase(PDF)

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0.0000 tetratricopeptide repeat (TPR) family protein0.0559 threonyl-tRNA synthetase0.0770 translation initiation factor IF-30.0797 50S ribosomal protein L350.0760 50S ribosomal protein L200.0760 4Fe-4S ferredoxin, iron-sulfur binding -like protein0.0934 xanthine phosphoribosyltransferase0.0218 phenylacetate-coenzyme A ligase0.0454 indolepyruvate oxidoreductase subunit iorB0.0298 indolepyruvate oxidoreductase subunit iorA0.0155 putative aminodeoxychorismate lyase0.0216 putative endonuclease BB04110.0025 putative xylose repressor0.0177 Pyridine nucleotide-disulphide oxidoreductase-like protein0.1922 hypothetical protein0.1561 arabinose-proton symporter0.2438 N-acylglucosamine 2-epimerase0.2795 alpha-N-acetylglucosaminidase precursor0.0289 SusC homolog0.0923 SusD homolog0.2808 putative chitobiase0.1137 glycerophosphoryl diester phosphodiesterase0.0665 thermostable beta-glucosidase B0.1648 hypothetical protein0.0247 endoglucanase E precursor (EGE)0.0003 conserved hypothetical protein0.1360 S-layer related protein precursor, sialic acid-specific 9-O-acetylesterase0.0144 putative metallophosphoesterase0.0025 conserved hypothetical protein, putative S-layer related protein precursor0.1521 conserved hypothetical protein0.0197 SusD homolog0.0781 SusC homolog0.0678 N-acylglucosamine 2-epimerase0.0760 arabinose-proton symporter (Arabinose transporter)0.0678 sialidase (Neuraminidase)0.0094 beta-hexosaminidase precursor0.0145 sialic acid-specific 9-O-acetylesterase0.1185 beta-mannosidase precursor0.2606 beta-hexosaminidase precursor0.2451 beta-hexosaminidase precursor0.0016 beta-galactosidase0.2233 putative transcriptional regulator0.0649 glucose-1-phosphate thymidylyltransferase0.2566 dTDP-4-dehydrorhamnose 3,5-epimerase

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0.0692 dTDP-4-dehydrorhamnose reductase0.1603 dTDP-glucose 4,6-dehydratase0.0073 putative flippase0.2870 putative F420H2-dehydrogenase 40 kDa subunit0.0132 hypothetical protein0.2823 hypothetical protein0.1799 glycoside transferase family 40.0124 putative acyltransferase in colanic acid biosynthesis0.2550 glycoside transferase family 20.1957 D-glycero-D-manno-heptose 1-phosphate kinase0.0516 putative phosphoheptose isomerase0.0998 D-mannose-1-phosphate guanyltransferase0.0219 putative phosphatase0.0233 glycoside transferase family 40.2032 glycoside transferase family 20.2962 glycosyltransferase0.0541 polysaccharide export outer membrane protein0.1262 tyrosine-protein kinase ptk0.1324 SusC homolog0.1332 SusD homolog

N/D transposase0.1786 altronate hydrolase0.1114 transcriptional regulator0.0000 2-dehydro-3-deoxygluconokinase0.0000 putative gluconate aldolase0.2719 conserved hypothetical protein0.1767 conserved hypothetical protein0.2980 integral membrane protein0.0195 conserved hypothetical protein0.0071 protoporphyrin IX magnesium chelatase0.1095 cobalamin biosynthesis protein0.1725 TonB-dependent receptor0.1713 putative lipoprotein0.2747 conserved hypothetical protein0.0781 cation efflux system protein0.0366 putative transport protein0.0087 conserved hypothetical protein0.0660 TonB-dependent outer membrane receptor0.0006 conserved hypothetical protein0.0234 TonB-dependent outer membrane receptor0.0334 Transcription factor like, MADS-box0.0000 beta-hexosaminidase precursor

N/D transcriptional regulator (TetR/AcrR family)0.0470 ABC transporter ATP-binding protein

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0.0270 ABC transporter ATP-binding/transmembrane protein0.1979 putative heme biosynthesis protein0.0000 hypothetical protein0.1981 hypothetical protein

N/D hypothetical protein0.3189 conserved hypothetical protein0.0276 terminal quinol oxidase, subunit, putative (doxD-like)0.1940 conserved hypothetical protein0.0957 flavodoxin0.1041 Bifunctional purine biosynthesis protein, putative 5-aminoimidazole-4-carboxamide ribonucleotide(AICAR) transformylase/IMP cyclohydrolase0.0637 protein with hemerythrin HHE cation binding region0.2829 transcriptional regulator0.0983 putative acetyl transferase0.0834 putative capsule-related protein0.0481 putative glycosyltransferase0.0616 putative two-component system response regulator0.0119 outer membrane protein0.1319 L-asparaginase I0.0000 tryptophan synthase alpha chain0.0028 putative N-(5'-phosphoribosyl)anthranilate isomerase0.0117 indole-3-glycerol phosphate synthase0.0000 anthranilate phosphoribosyltransferase0.0334 anthranilate synthase component II0.0000 anthranilate synthase component I0.0002 tryptophan synthase beta chain0.0040 hypothetical protein0.0224 iron-containing alcohol dehydrogenase0.2161 two-component system sensor protein0.0132 putative two-component system sensor kinase/response regulator0.2676 hypothetical protein0.0019 putative Na+/sulphate transporter0.0770 putative exopolyphosphatase0.0783 Polyphosphate kinase0.2048 tRNA/rRNA methyltransferase, SpoU-like protein0.2836 glutamine synthetase0.1176 ammonium transporter

N/D nitrogen regulatory protein P-II0.0781 conserved hypothetical protein0.0676 aspartate aminotransferase0.0582 diaminopimelate epimerase0.0370 putative thioredoxin0.1696 putative glycerophosphodiester phosphodiesterase0.2182 asparagine synthetase B, glutamine-hydrolyzing

N/D glutamate synthase, small subunit

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0.0000 glutamate synthase, large subunit0.0000 glucosamine--fructose-6-phosphate aminotransferase0.0000 amidophosphoribosyltransferase0.0000 carbamoyl phosphate synthetase III (glutamine-hydrolyzing)0.0000 carbamyl phosphate synthetase0.1295 mannose-1-phosphate guanylyltransferase0.0126 transcriptional regulator0.0314 outer membrane efflux protein0.0000 putative ABC transport system, lipoprotein0.0327 putative ABC transporter ATP-binding protein0.0255 putative ABC transporter ATP-binding protein or permease protein0.0350 putative ABC transporter permease protein0.0628 putative heat shock protein0.0418 alanyl-tRNA synthetase0.2273 putative protein involved in barrier function of the cell envelope0.0139 conserved hypothetical protein0.0099 putative acylhydrolase0.0000 excinuclease ABC subunit B0.0997 phenylacetate-coenzyme A ligase0.1340 Acetohydroxyacid synthase small subunit Related0.0337 lipoprotein protein, putative0.1589 conserved hypothetical protein0.2473 conserved hypothetical protein0.2914 conserved hypothetical protein0.1569 LysM-repeat protein0.1345 excinuclease ABC subunit A0.0102 putative transcription regulator0.2793 putative H+/peptide symporter0.1511 putative acetyltransferase, GNAT family0.0912 Transcriptional regulator PadR-like protein0.0586 putative membrane protein0.0688 putative outer membrane protein0.2607 Flavin reductase-like, FMN-binding0.0364 hypothetical protein0.0760 prolyl oligopeptidase family protein0.2639 BexA, multidrug efflux pump0.0265 conserved hypothetical protein0.0205 CTP synthase (UTP-ammonia ligase)0.2917 hypothetical protein0.1940 conserved hypothetical protein0.0765 conserved hypothetical protein0.0754 hypothetical protein0.2495 integrase0.0411 putative transcriptional regulator

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0.0632 conserved hypothetical protein0.0097 putative nucleoside-diphosphate sugar epimerases/dehydrase0.3158 UDP-glucose 6-dehydrogenase0.1981 nucleotide sugar epimerase0.3100 UDP-N-acetylglucosamine 2-epimerase0.2538 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase0.2953 conserved hypothetical protein0.1502 putative coenzyme F420-reducing hydrogenase0.2749 putative polysaccharide export protein0.0244 hypothetical protein0.2495 serine O-acetyltransferase0.2829 glycoside transferase family 40.2041 glycoside transferase family 40.0869 lipopolysaccharide biosynthesis protein, putative glycosyltransferase0.0308 glycosyltransferase0.2267 putative aminotransferase0.0313 putative membrane protein involved in polysaccharide export0.1940 putative tyrosine-protein kinase in cps region0.0057 putative non-specific DNA binding protein0.0001 Positive regulator of sigma(E)0.0000 Na+-transporting NADH:ubiquinone oxidoreductase, Electron transport complex protein rnfB0.0000 Na+-transporting NADH:ubiquinone oxidoreductase, Electron transport complex protein rnfC0.0000 Na+-transporting NADH:ubiquinone oxidoreductase, Electron transport complex protein rnfD0.0000 Na+-transporting NADH:ubiquinone oxidoreductase, Electron transport complex protein rnfG0.0000 Na+-transporting NADH:ubiquinone oxidoreductase, Electron transport complex protein rnfE0.0000 Na+-transporting NADH:ubiquinone oxidoreductase, Electron transport complex protein rnfA0.0000 putative UDP-glucose 4-epimerase0.1253 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase0.0505 DNA helicase0.1721 phenylalanyl-tRNA synthetase beta chain0.0000 conserved hypothetical protein, with a conserved domain of unknown function0.0021 conserved hypothetical protein0.1948 Mn2+ and Fe2+ transport protein0.2214 exodeoxyribonuclease0.0680 conserved hypothetical protein0.1479 GTP-binding protein, membrane GTPase lepA0.0139 putative Na+/H+ exchange protein0.0007 Na+/H+ antiporter 10.2069 putative transcriptional regulator0.3019 putative transcriptional regulator0.0065 DNA recombination protein rmuC-like protein0.0192 putative methionine aminopeptidase A0.0332 conserved hypothetical protein0.1615 Fe-S oxidoreductases family 2

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0.0930 conserved hypothetical protein0.0126 RNA pseudouridylate synthase0.0425 RNA methyltransferase0.0508 pyruvate phosphate dikinase0.0948 conserved hypothetical protein0.0314 conserved hypothetical protein0.0066 thiamine phosphate pyrophosphorylase0.0011 molybdopterin biosynthesis protein0.2707 thiamine biosynthesis protein ThiH0.0027 thiamine biosynthesis protein ThiC0.0047 thiamine biosynthesis protein ThiG0.0027 putative thiamine-phosphate pyrophosphorylase0.0687 thiS protein, involved in thiamine biosynthesis0.2003 two-component sensor histidine kinase0.0176 superoxide dismutase (Fe)0.2839 conserved hypothetical protein0.0014 ATP-dependent DNA helicase0.1305 hypothetical protein0.2650 conserved hypothetical protein0.0455 Prokaryotic ATPase0.0666 conserved hypothetical protein0.2287 O-antigen polymerase0.2598 hypothetical protein0.2316 conserved hypothetical protein0.0033 Fibronectin, type III-like fold0.0064 hypothetical protein0.0663 signal peptidase I (SPase I)0.1802 conserved hypothetical protein0.0916 putative cation efflux system protein0.2048 putative cation efflux system0.1666 outer membrane protein TolC, putative0.0343 drug efflux protein0.0324 NADP(H) oxidoreductase0.0034 carboxynorspermidine decarboxylase0.0226 N-acetylglucosamine-6-phosphate deacetylase0.0091 N-acetylglucosamine-6-phosphate deacetylase0.0538 thioredoxin (TRX)0.0117 cation efflux system protein czcC0.0173 cation efflux system protein czcB0.0117 cation efflux system protein czcA0.0195 two-component system sensor histidine kinase0.0162 two-component system response regulator0.0566 alpha-glucosidase0.0267 putative long-chain-fatty-acid--CoA ligase

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0.0490 putative Na+/H+ exchanger0.0328 putative uracil permease (uracil transporter)0.0384 prismane protein0.0758 cAMP-binding domain (catabolite gene activator) transcriptional regulator0.0001 putative two-component system sensor histidine kinase0.1288 two-component system response regulator0.0027 conserved hypothetical protein0.0324 putative calcineurin superfamily phosphohydrolase0.0408 putative ABC transport system, membrane protein0.1682 ABC transporter, ATP-binding protein0.2664 ABC transporter, permease protein0.0068 putative membrane protein0.0733 putative phosphatase/phosphohexomutase0.1730 3-methyl-2-oxobutanoate hydroxymethyltransferase0.1258 putative sugar transporter0.1213 GTP pyrophosphokinase0.2531 putative ATPase/kinase0.0526 chloramphenicol acetyltransferase (CAT-III)0.1648 conserved hypothetical protein0.2276 phosphoribosylglycinamide formyltransferase 20.0075 conserved hypothetical protein

N/D putative N-acetylmuramoyl-L-alanine amidase0.1301 putative non-specific DNA binding protein

N/D conserved hypothetical protein0.1298 hypothetical protein0.0705 hypothetical protein0.2619 ATP synthase beta chain0.0312 ATP synthase epsilon chain0.1592 conserved hypothetical protein0.1028 ATP synthase A subunit0.0595 ATP synthase C subunit0.3140 ATP synthase B subunit0.1909 ATP synthase delta chain0.2845 ATP synthase alpha chain0.0029 ATP synthase gamma chain0.1040 putative lipoprotein0.0083 DNA repair and recombination protein, putative helicase0.0047 conserved hypothetical protein, putative surface protein0.0334 Lipase, active site0.2448 hypothetical protein0.1854 dTDP-4-dehydrorhamnose reductase

N/D conserved hypothetical protein0.0115 clostripain-related protein0.0005 transcriptional regulator

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0.1071 transcriptional regulator0.1042 putative mRNA-binding protein0.0013 conserved hypothetical protein0.2331 two-component system response regulator0.1383 two-component system sensor histidine kinase0.1940 TonB-dependent receptor0.0617 aspartate decarboxylase AsdA0.0010 putative transport protein0.0758 formate--tetrahydrofolate ligase0.0126 serine hydroxymethyltransferase0.2398 conserved hypothetical protein0.0146 flavoredoxin0.0000 aspartate carbamoyltransferase regulatory chain0.0000 aspartate carbamoyltransferase catalytic chain0.1900 penicillin-binding protein 1A (PBP-1a)0.2962 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0.1674 3-deoxy-manno-octulosonate cytidylyltransferase0.0244 putative zinc protease0.0003 putative phosphatidylinositol-4-phosphate 5-kinase0.0592 ribose-phosphate pyrophosphokinase0.1738 putative two-component system sensor histidine kinase0.0641 probable two-component system response regulator0.1974 putative efflux pump component protein0.0051 putative RNA polymerase ECF-type sigma factor0.0190 putative anti-sigma factor0.0293 SusC homolog0.0042 SusD homolog0.0000 iduronate 2-sulfatase precursor0.0082 beta-galactosidase0.0641 acetyltransferase

N/D hypothetical protein0.1316 two-component system response regulator0.1397 conserved hypothetical protein0.1602 hypothetical protein0.0015 TPR repeat-containing protein0.1067 hypothetical protein0.0879 putative protease0.1779 conserved hypothetical protein0.0000 putative para-aminobenzoate synthase component I

N/D putative para-aminobenzoate synthase component I0.0000 conserved hypothetical protein0.0000 conserved hypothetical protein0.0000 1,4-alpha-glucan branching enzyme (isoamylase or pullulanase type II)0.0520 putative lipoprotein

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0.0000 alpha-amylase 30.0000 conserved protein with a conserved patatin-like phospholipase domain0.1826 ferredoxin-type protein0.0002 conserved hypothetical protein0.2018 putative transmembrane protein0.1966 Polyphosphate kinase 2-like protein0.0342 conserved hypothetical protein0.2985 acetyltransferase0.0100 conserved hypothetical protein0.0936 hypothetical protein0.0657 hypothetical protein0.1674 putative RNA-binding protein0.0782 glutamine synthetase I0.2560 putative integral membrane protein0.0495 succinyl-CoA synthetase alpha chain0.1459 succinyl-CoA synthetase beta chain0.0110 malonyl CoA-acyl carrier protein transacylase0.0274 phosphomethylpyrimidine kinase0.0781 NUDIX hydrolase0.1878 xylulose kinase (xylulokinase)0.0387 xylose isomerase0.0000 D-xylose-proton symporter (D-xylose transporter)0.1624 DNA-binding protein-like protein0.1729 putative helicase0.2672 transcriptional regulator, ArsR family0.0797 redox-active disulfide protein-like protein0.0680 Thioredoxin fold protein0.0001 putative cytochrome c biogenesis protein0.0136 arsenical resistance operon trans-acting repressor0.0671 arsenical pump-driving ATPase0.2111 integral membrane efflux pump, putative multidrug-efflux transporter0.0144 putative carbon-nitrogen hydrolase0.2220 putative membrane protein0.1649 isoleucyl-tRNA synthetase0.2836 DnaK suppressor protein, putative0.0671 putative signal peptidase0.0000 putative lipoprotein0.0502 conserved hypothetical protein0.0272 putative tRNA/rRNA methyltransferase0.1846 putative transcriptional regulator0.1825 TonB0.0009 conserved hypothetical protein, putative outer membrane protein0.1463 conserved hypothetical protein0.3044 DoxX-like protein

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0.0772 lipoprotein0.0018 two-component system sensor histidine kinase0.0314 hypothetical protein0.0133 conserved hypothetical protein0.0055 putative permease0.0176 putative metallo-beta-lactamase superfamily hydrolase0.0680 uronate isomerase0.0011 transcriptional regulator (LacI family)0.1251 altronate oxidoreductase0.2513 putative FHA domain protein0.0033 Sporulation related0.0194 dTDP-4-dehydrorhamnose 3,5-epimerase0.0541 UDP-glucose 6-dehydrogenase0.0783 putative lipoprotein0.0028 ATP-dependent RNA helicase0.0233 putative phosphoserine phosphatase0.0393 conserved hypothetical protein0.1470 putative permease0.0770 tRNA-guanine transglycosylase0.0512 ATP-dependent protease0.1863 ATP-dependent protease0.0273 putative RNA methyltransferase0.0853 hypothetical protein0.0306 conserved hypothetical protein0.0061 hypothetical protein0.2099 hypothetical protein0.2641 hypothetical protein0.0427 hypothetical protein0.1449 hypothetical protein0.0366 hypothetical protein0.0022 hypothetical protein0.0687 hypothetical protein0.0781 hypothetical protein0.2834 putative transcriptional regulator0.0442 hypothetical protein0.0741 hypothetical protein0.0063 putative methyltransferase0.0095 hypothetical protein0.0202 two-component system sensor histidine kinase0.0148 two-component system response regulator0.0742 outer membrane protein TolC, putative0.2664 putative ABC transporter permease0.2754 putative ABC transporter permease0.0166 putative ABC transporter ATP-binding protein

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0.0770 putative ABC transporter permease0.0342 putative ABC-transporter permease protein0.1603 putative ABC transporter permease0.0614 putative permease0.0923 putative chitobiase0.0581 SusD homolog0.2604 SusC homolog0.0781 hypothetical protein0.0760 conserved hypothetical protein0.0000 8-amino-7-oxononanoate synthase0.0045 diacylglycerol kinase-like, catalytic region0.0885 aspartyl-tRNA synthetase0.0040 putative sulfatase0.0216 GtrA-like protein0.0454 beta-ureidopropionase0.0577 putative deiminase0.0977 ferredoxin domain containing protein0.0000 ABC transporter, ATP-binding protein0.2637 ABC transporter, permease protein0.1844 conserved hypothetical protein0.0942 conserved hypothetical protein0.0678 putative NIF3-related protein0.0758 conserved hypothetical protein0.1587 outer membrane efflux protein oprM precursor0.0691 putative cation efflux pump0.1803 putative cation efflux pump0.2347 conserved hypothetical protein0.1394 AMP nucleosidase0.1594 DNA polymerase III-like, delta subunit0.2366 putative DNA-binding protein0.0000 dihydroorotate dehydrogenase electron transfer subunit0.0000 dihydroorotate dehydrogenase0.1586 tRNA (Guanine-N(1)-methyltransferase0.0473 DNA ligase0.2954 dihydrodipicolinate synthase0.0913 putative patatin-like phospholipase0.0833 chaperone protein htpG (heat shock protein htpG)0.0185 ATP-dependent Clp protease0.1582 DNA gyrase subunit A0.0000 putative tetratricopeptide repeat family protein0.1630 putative universal stress protein UspA0.1236 conserved hypothetical protein0.0000 BatE, TRP domain containing protein0.0000 BatD, conserved hypothetical protein

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0.0000 BatC, conserved hypothetical protein0.0000 BatB, conserved hypothetical protein0.0000 BatA0.0000 putative conserved membrane exported protein0.0000 von Willebrand factor-like, type A0.0000 magnesium chelatase, subunit I0.1499 putative integration host factor IHF alpha subunit0.2829 DNA-binding protein HU0.0447 putative Fe-S oxidoreductase0.0885 recognition particle-docking protein FtsY0.0797 50S ribosomal protein L330.0770 50S ribosomal protein L280.0770 competence-damage inducible protein

N/D integraseN/D hypothetical protein

0.0586 putative O-sialoglycoprotein endopeptidase0.0000 conserved hypothetical protein0.0347 putative lipoprotein0.1383 putative periplasmic protein0.0067 S-layer domain containing protein0.1857 ABC transporter, ATP-binding protein0.1142 ABC-type transport, permease protein0.1549 two-component system sensor histidine kinase0.0765 two-component system response regulator0.1638 prolyl-tRNA synthetase0.0593 hypothetical protein0.0679 hypothetical protein0.0022 hypothetical protein0.1940 hypothetical protein0.2628 hypothetical protein0.0797 hypothetical protein0.2132 hypothetical protein0.0158 hypothetical protein0.0000 hypothetical protein0.0081 hypothetical protein0.0002 hypothetical protein0.0018 hypothetical protein0.0777 putative dinitrogenase reductase activating glycohydrolase0.1477 penicillin-binding protein 2B (PBP-2B)0.0153 hypothetical protein0.0448 hypothetical protein0.2940 hypothetical protein0.2453 integrase0.1785 conserved hypothetical protein

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0.0760 hypothetical protein0.0001 conserved hypothetical protein0.0626 hypothetical protein0.2080 hypothetical protein0.2817 integrase0.2600 putative outer membrane protein0.0431 conserved hypothetical protein, putative membrane protein0.0081 conserved hypothetical protein, putative transmembrane protein0.2607 putative transport-related membrane protein0.2676 two-component system sensor histidine kinase/response regulator, hybrid (one component system)0.2438 putative transmembrane protein0.0374 putative TonB-dependent outer membrane receptor

N/D putative TonB-dependent outer membrane receptor0.2451 aldo/keto reductase0.0061 putative ferredoxin-type protein0.1426 putative outer membrane protein, probably involved in nutrient binding0.2664 putative anti-sigma factor0.1080 RNA polymerase ECF-type sigma factor0.0562 hypothetical protein0.1410 conserved hypothetical protein0.0068 hypothetical protein0.0879 haloacid dehalogenase-like hydrolase0.0110 conserved hypothetical protein0.0550 putative oxidoreductase0.2214 conserved hypothetical protein0.0000 conserved hypothetical protein, putative integral membrane protein0.0000 conserved hypothetical protein, putative integral membrane protein0.2639 putative transport protein0.0690 hypothetical protein0.0332 ECF-type sigma factor0.1210 Pectin lyase fold/virulence factor0.0424 putative pectate lyase0.0000 two-component system sensor histidine kinase/response regulator, hybrid (one component system)0.1255 hypothetical protein0.1102 beta-galactosidase0.0392 conserved hypothetical protein0.1261 putative sialic acid-specific acetylesterase II0.1744 Glycoside hydrolase family 2, sugar binding protein0.2882 putative cytochrome C-type biogenesis protein0.1118 Mg2+ transport ATPase protein B0.0234 two-component system sensor histidine kinase0.1940 two-component system response regulator0.0464 putative transporter0.1551 beta-galactosidase

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0.1951 beta-galactosidase0.2836 two-component system histidine kinase0.1765 transcription regulator, AraC-type0.0348 beta-galactosidase0.0073 conserved hypothetical protein0.0090 two-component system sensor histidine kinase0.0780 putative acetyltransferase0.0489 probable ABC transporter permease0.2782 putative alpha-rhamnosidase0.0358 Pectin lyase fold/virulence factor0.2449 Six-hairpin glycosidase0.0598 Claudin tight junction protein0.0639 hypothetical protein0.0961 putative nitroreductase0.0781 putative lipoprotein0.2732 xylanase0.2601 dihydroorotate dehydrogenase0.0095 glycoside hydrolase family 950.0642 glycoside hydrolase family 150.0460 conserved hypothetical protein0.0006 putative alpha-rhamnosidase0.0831 hypothetical protein0.0983 putative oxidoreductase0.2953 conserved protein with a conserved patatin-like phospholipase domain0.2660 conserved hypothetical protein0.0418 polygalacturonase (Pectinase)0.0804 glycoside hydrolase family 780.0000 Six-hairpin glycosidase0.0258 arabinosidase0.1728 conserved hypothetical protein0.0008 putative pectate lyase0.1459 SusD homolog0.1424 SusC homolog0.0320 hypothetical protein0.0524 hypothetical protein0.0000 SusD homolog0.1283 SusC homolog0.1477 Fibronectin, type III-like fold0.0208 Xylose isomerase-like TIM barrel0.1053 alpha-1,2-mannosidase family protein0.3171 Glycosidase, PH117-related0.1214 putative signal transducer0.1238 Coagulation factor 5/8 type, C-terminal0.0087 Coagulation factor 5/8 type, C-terminal

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0.0047 Concanavalin A-like lectin/glucanase0.0003 putative secreted endoglycosidase0.0852 SusD homolog0.1684 SusC homolog0.1947 integrase0.0818 SusC homolog0.0042 SusD homolog0.0037 putative secreted endoglycosidase, GH family 180.0172 Concanavalin A-like lectin/glucanase0.0890 SusC homolog0.0890 SusD homolog0.2252 putative secreted endoglycosidase0.2191 putative patatin-like protein0.0034 Coagulation factor 5/8 type, C-terminal0.1597 beta-hexosaminidase precursor0.0195 putative anti-sigma factor0.1264 RNA polymerase ECF-type sigma factor0.0312 ATP-dependent helicase0.2630 pyruvate formate-lyase activating enzyme0.0001 TonB-like protein0.0172 putative exonuclease0.0000 two-component system sensor histidine kinase0.0000 putative UDP-glucose 4-epimerase0.0793 conserved hypothetical protein0.2948 Lambda repressor-like, DNA-binding protein0.0062 putative lipoprotein0.1019 putative lipoprotein0.0000 Rhodopsin-like GPCR superfamily0.0760 hypothetical protein0.0760 conserved hypothetical protein0.0454 conserved hypothetical protein0.2672 hypothetical protein0.1987 conserved hypothetical protein, putative transcriptional regulator0.1154 Predicted phosphoadenosine phosphosulfate reductase0.2305 conserved hypothetical protein0.0781 conserved hypothetical protein0.0285 conserved hypothetical protein0.0558 conserved hypothetical protein0.0649 putative two-component system sensor protein, but no histidine kinase domain0.1803 two-component system response regulator0.0904 putative aspartate aminotransferase0.0977 putative transcriptional regulator0.2021 acetyltransferase0.2191 putative transmembrane protein

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0.0002 recombination protein recR0.2782 Na+/solute symporter0.2744 putative GTP-binding protein0.0680 conserved hypothetical protein0.0001 putative lipoprotein0.2817 putative oligopeptide transporter0.0452 putative xylanase0.0638 conserved hypothetical protein0.0025 lipoate-protein ligase B0.0652 AraC-type transcription regulator0.0001 cation-transporting ATPase pacS

N/D putative heavy-metal binding protein0.2807 conserved hypothetical protein, putative TonB-dependent outer membrane receptor protein0.0160 hypothetical protein0.1566 Putative DNA binding protein0.0545 transposase0.1767 hypothetical protein0.0414 methylglyoxal synthase0.1295 putative arginase0.0197 alpha-glucan phosphorylase0.1019 putative sodium/proton antiporter0.0186 6-phosphofructokinase0.0610 RNA polymerase ECF-type sigma factor0.0664 small heat shock protein0.0268 phosphoglycerate mutase 10.0049 fructose-bisphosphate aldolase class I0.2429 ferritin A0.0244 conserved hypothetical protein, putative integral membrane protein0.0311 ferritin A0.0492 hypothetical protein0.0047 hypothetical protein0.1940 transposase0.0319 flavodoxin0.2829 putative exporter protein0.0042 aldo/keto reductase0.0630 conserved hypothetical protein0.0015 conserved hypothetical protein, with a cAMP-binding domain0.1762 SusD homolog0.0105 SusC homolog0.0000 hypothetical protein0.1255 conserved hypothetical protein, with a carboxymuconolactone decarboxylase domain0.0357 conserved hypothetical protein0.0064 transcriptional regulator0.0586 putative integrase

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0.0760 hypothetical protein0.0648 mobilization protein BmgA0.2681 mobilization protein BmgB0.0527 hypothetical protein0.1940 Putative DNA binding protein0.0742 Putative DNA binding protein0.2492 hypothetical protein0.0690 hypothetical protein0.1472 hypothetical protein0.0691 hypothetical protein0.0670 conserved hypothetical protein0.0647 hypothetical protein0.0770 hypothetical protein0.0687 transposase0.0226 putative TonB-dependent outer membrane receptor0.1259 conserved hypothetical protein0.0003 cation efflux family protein0.0000 Concanavalin A-like lectin/glucanase0.0296 conserved hypothetical protein0.3140 conserved hypothetical protein0.3176 glucose-inhibited division protein0.0940 putative metallo-beta-lactamase0.3071 glycine dehydrogenase, decarboxylating0.2214 putative NADH dehydrogenase/NAD(P)H nitroreductase0.0737 Type II restriction enzyme HpaII0.0891 DNA polymerase III-like, beta chain0.0536 conserved hypothetical protein0.0401 D-3-phosphoglycerate dehydrogenase0.0083 phosphoserine aminotransferase0.0342 ATP-independent RNA helicase0.0000 Na+-translocating NADH-quinone reductase subunit0.0000 Na+-translocating NADH-quinone reductase subunit0.0000 Na+-translocating NADH-quinone reductase subunit0.0000 Na+-translocating NADH-quinone reductase subunit0.0000 Na+-translocating NADH-quinone reductase subunit0.0000 Na+-translocating NADH-quinone reductase subunit0.0088 putative aminopeptidase C0.0002 putative outer membrane protein0.1495 putative outer membrane protein0.0366 putative transmembrane protein0.0084 putative transmembrane surface-related protein0.2437 glycoside transferase family 20.1230 glycoside transferase family 2

N/D N-acetylmuramoyl-L-alanine amidase

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0.3097 hypothetical protein0.0282 hypothetical protein0.0380 glyoxalase family-like protein0.0269 DNA primase/helicase0.0960 hypothetical protein0.0276 hypothetical protein0.0112 conserved hypothetical protein0.2253 glycoside transferase family 20.1151 putative polysaccharide biosynthesis protein0.2584 glycosyl transferase, group 1

N/D glycosyltransferase, family 80.3103 glycoside transferase family 40.0427 glycoside transferase family 20.0642 conserved hypothetical protein0.0091 two-component system sensor histidine kinase/response regulator, hybrid (one component system)0.0554 putative transmembrane endonuclease/exonuclease0.0044 OmpA-related protein0.0758 ABC transporter ATP-binding protein0.0843 transcriptional regulator

N/D putative transcription regulator0.0202 putative transcription activator0.1372 putative ATP GTP-binding protein0.1365 hypothetical protein0.0002 putative xylanase0.0142 conserved hypothetical protein0.0334 outer membrane protein, OmpA family0.0494 monofunctional biosynthetic peptidoglycan transglycosylase0.0006 pyruvate carboxylase subunit B)0.0000 RNA polymerase ECF-type sigma factor0.1779 LemA protein0.0300 putative protease0.2091 conserved hypothetical protein0.2258 putative yadS-like transmembrane protein0.2504 UDP-N-acetylglucosamine 2-epimerase0.0705 putative UDP-N-acetylglucosamine 2-epimerase0.0025 conserved hypothetical protein, putative outer membrane protein0.3071 putative ATPase, AAA family0.0015 conserved hypothetical protein0.0424 glycerate dehydrogenase (NADH-dependent)0.0326 conserved hypothetical protein0.0928 cytochrome D ubiquinol oxidase subunit II0.2135 cytochrome D ubiquinol oxidase subunit I0.0977 conserved hypothetical protein0.2142 outer membrane efflux protein

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0.0150 periplasmic component of efflux system0.0133 putative ABC transporter ATP-binding protein0.1885 ABC transporter, permease protein0.3058 putative two-component system sensor protein, without kinase domain0.2263 two-component system response regulator0.0003 conserved hypothetical protein, with conserved domain0.1940 putative peroxidase family protein0.0000 6-phosphogluconolactonase0.0000 glucose-6-phosphate 1-dehydrogenase0.0000 6-phosphogluconate dehydrogenase,decarboxylating0.2429 Na+/H+-dicarboxylate symporter0.0357 GDP-mannose 4,6-dehydratase0.3065 GDP-fucose synthetase0.0158 putative long-chain-fatty-acid--CoA ligase0.0390 conserved hypothetical protein0.1005 fructose-1,6-bisphosphatase0.0023 conserved hypothetical protein, putative membrane protein0.0013 hypothetical protein0.2337 hypothetical protein0.0945 hypothetical protein0.0018 hypothetical protein0.1707 conserved hypothetical protein0.0719 AraC-type transcription regulator0.0029 2,3-cyclic-nucleotide 2-phosphodiesterase precursor0.2550 two-component system sensor histidine kinase0.0343 putative RNA binding protein with S1 RNA-binding domain0.0185 putative metal-dependent membrane protease0.0194 conserved hypothetical protein0.2676 hypothetical protein0.1375 ABC transporter ATP-binding protein0.2454 GrpE protein (Hsp-70 cofactor)0.0819 chaperone protein dnaJ

N/D transposaseN/D transposase

0.1240 hypothetical protein0.0000 putative transport protein0.1149 putative multidrug resistance protein0.0033 conserved hypothetical protein, putative outer membrane efflux protein0.1733 transcriptional regulator, MarR family0.0172 possible transmembrane protein0.2144 conserved hypothetical protein0.1339 inner membrane protein0.0000 hypothetical protein0.1902 conserved hypothetical protein

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0.0549 helicase-like protein0.0081 putative acetyltransferase0.0370 choloylglycine hydrolase0.0085 putative peptidase0.0818 peptidase0.2245 putative transcriptional regulator0.0716 putative protease I0.0083 two-component system sensor histidine kinase

N/D two-component system response regulator0.0312 putative two-component system sensor protein0.1954 outer membrane protein0.2359 transporter, AcrB/D/F family0.2906 component of multidrug efflux system0.1348 putative Na+/H+ antiporter0.0001 30S ribosomal protein S160.0072 FucR0.1472 L-fucose isomerase0.0464 L-fuculose-1-phosphate aldolase0.0036 L-fuculose kinase

N/D Rhamnose mutarotase0.0274 L-fucose permease0.2502 RNA polymerase ECF-type sigma factor0.0139 putative anti-sigma factor0.0923 SusC homolog0.0663 SusD homolog0.0011 conserved hypothetical protein0.2750 putative patatin-like protein0.0818 putative endo-beta-N-acetylglucosaminidase F1 precursor (mannosyl-glycoprotein endo-beta-N-acetyl-glucosaminidase F1)0.0955 endo-beta-N-acetylglucosaminidase0.0000 putative two-component system response regulator0.0586 conserved hypothetical protein0.0194 spermidine/putrescine ABC transporter0.1061 putrescine transport system permease protein potI0.1053 putrescine transport system permease protein potH0.0760 spermidine/putrescine transport ATP-binding protein0.2507 thiol:disulfide interchange protein0.0000 alpha-glucan phosphorylase0.0000 glycogen [starch] synthase, glycosyltransferase0.0000 V-type sodium ATP synthase subunit K0.0001 V-type ATP synthase subunit I0.0000 V-type ATP synthase subunit D0.0005 V-type ATP synthase subunit B0.0035 V-type ATP synthase subunit A0.0002 conserved hypothetical protein

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0.0052 ATP synthase subunit E0.1010 hypothetical protein0.1995 conserved hypothetical protein0.3181 putative transcriptional regulator0.1769 conserved hypothetical protein0.0505 putative ABC transporter ATP-binding protein0.0032 hypothetical protein0.0001 clostripain-related protein0.3140 conserved hypothetical protein0.0266 conserved hypothetical protein0.0547 RNA polymerase sigma factor rpoD (Sigma-A)0.0046 serine protease precursor0.1638 muconate cycloisomerase0.0002 dipeptidyl-peptidase VI0.0046 ribonuclease BN0.0052 putative NADH dehydrogenase/NAD(P)H nitroreductase0.0647 riboflavin synthase alpha chain0.1327 signaling protein without kinase domain0.0003 two-component system response regulator0.0584 putative transcriptional regulator, phosphate uptake regulation0.0948 putative phosphate transport ATP-binding protein0.0980 putative ABC transporter permease protein0.0547 putative ABC transporter permease protein0.0000 phosphate ABC transporter, phosphate-binding protein0.0233 glutaminyl-tRNA synthetase0.0000 TPR domain-containing protein0.0000 putative alkaline phosphatase0.1330 conserved hypothetical protein0.0563 putative thiol peroxidase0.2955 conserved hypothetical protein0.2697 conserved hypothetical protein0.1821 putative racemase0.0691 putative dihydropyrimidine dehydrogenase [NADP+] precursor0.0015 PhoH-like protein0.1728 folylpolyglutamate synthase0.2513 putative translation initiation inhibitor0.0004 putative aminopeptidase C0.0894 dTDP-4-dehydrorhamnose 3,5-epimerase0.0000 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase0.0000 putative lipopolysaccharide biosynthesis glycosyltransferase0.0000 UDP-glucose 6-dehydrogenase0.0000 putative UDP-glucuronic acid epimerase0.0000 putative capsule biosynthesis protein0.0000 glycoside transferase family 4

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0.0000 glycosyltransferase0.0000 capsule biosynthesis protein capA0.0000 glycoside transferase family 20.0000 CDP-abequose synthase0.0000 dTDP-4-dehydrorhamnose epimerase-like protein0.0000 CDP-glucose 4,6-dehydratase0.0000 glucose-1-phosphate cytidylyltransferase0.0000 glycoside transferase family 40.0000 glycoside transferase family 20.0000 putative flippase0.0000 putative protein involved in capsular polysaccharide biosynthesis0.0000 putative capsule polysaccharide export protein0.0000 conserved hypothetical protein0.0000 putative transcriptional regulator0.1296 Tetratricopeptide repeat family protein0.1322 tRNA/rRNA methyltransferase0.0004 DNA repair protein recN (Recombination protein N)0.1423 flavoprotein0.1481 DNA Pol III Epsilon Chain0.1087 DNA polymerase III, beta chain0.2023 conserved hypothetical protein0.0019 conserved hypothetical protein0.0149 hydrolase, metal-dependent0.1577 UDP-N-acetylenolpyruvoylglucosamine reductase0.2202 conserved hypothetical protein0.0486 NAD dependent nucleotide-diphosphate-sugar epimerase0.1524 2-amino-3-ketobutyrate coenzyme A ligase0.0627 conserved hypothetical protein0.2706 ferritin A0.0000 diaminopimelate decarboxylase0.0000 aspartokinase0.0000 putative ATP-binding protein involved in cell division0.0000 phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase0.0002 imidazole glycerol phosphate synthase subunit hisF0.0014 phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase0.0009 imidazole glycerol phosphate synthase subunit hisH0.0005 formyltetrahydrofolate deformylase0.2281 putative protease0.1075 oxidoreductase, aldo/keto reductase0.2636 conserved hypothetical protein0.2658 transcriptional regulator0.2962 conserved hypothetical protein0.1499 putative Na+-driven multidrug efflux pump0.2454 integral membrane protein

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0.3063 conserved hypothetical protein0.0346 conserved hypothetical protein0.1442 Bacterial outer membrane protein

N/D conserved hypothetical protein0.3122 4-carboxymuconolactone decarboxylase0.0444 putative flavoredoxin0.2612 Flavodoxin0.0290 transcription regulator, AraC family0.0625 putative membrane protein0.0746 putative aminotransferase B0.0353 conserved hypothetical protein0.0150 putative hydrolase0.0120 putative sugar transport protein0.0061 iron-sulfur flavoprotein0.2466 1-deoxy-D-xylulose 5-phosphate synthase0.1821 putative transcriptional regulator0.1515 conserved hypothetical protein0.2327 transcriptional regulator, TetR family0.0137 activator of (R)-2-hydroxyglutaryl-CoA dehydratase0.0616 putative Tricorn-like protease0.0599 putative homocysteine S-methyltransferase0.0033 putative metallo-beta-lactamase0.2071 methylated-DNA--protein-cysteine methyltransferase0.2637 iron-sulfur flavoprotein0.2676 putative transcription regulator0.0198 conserved hypothetical protein0.0002 cytochrome c biogenesis protein ccsA0.0020 putative transmembrane protein0.0004 cytochrome C552 precursor0.0018 quinol oxidase0.0505 conserved hypothetical protein0.0716 putative TonB receptor0.0025 conserved hypothetical protein0.2466 conserved hypothetical protein0.0780 conserved hypothetical protein0.1467 Histone-like bacterial DNA-binding protein0.2229 conserved hypothetical protein0.0162 conserved hypothetical protein0.0156 tetracycline resistance element mobilization regulatory protein rteC0.3190 conserved hypothetical protein0.2401 putative general stress protein0.0291 transcriptional regulator0.0130 putative DNA polymerase III epsilon chain0.1662 mannonate dehydratase

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0.0786 putative oxidoreductase0.0903 transcriptional regulator, putative catabolite control protein A0.0202 conserved hypothetical protein0.1648 Transglycosylase-associated protein0.2990 glycerate kinase family protein0.0895 putative membrane efflux protein0.1091 SusD homolog0.0017 SusC homolog0.0470 conserved hypothetical protein0.1307 adenosylmethionine-8-amino-7-oxononanoate aminotransferase0.1379 8-amino-7-oxononanoate synthase0.0011 putative biotin synthesis-related fusion protein0.2887 putative biotin synthesis protein bioC0.0084 dethiobiotin synthetase0.1635 two-component system sensor histidine kinase0.0004 biotin carboxyl carrier protein0.0021 biotin carboxylase0.2233 propionyl-CoA carboxylase beta chain0.0902 conserved hypothetical protein0.2951 putative outer membrane protein0.0467 L-lactate permease0.0680 putative peptide chain release factor0.3121 protein rtcB0.0018 thioredoxin (TRX)0.2550 two-component system response regulator0.0018 putative two-component system sensor histidine kinase0.0053 putative two-component system sensor histidine kinase, no kinase domain0.1148 putative TonB dependent outer membrane protein0.1779 conserved hypothetical protein0.0742 conserved hypothetical protein0.0233 putative acetyltransferase0.0016 putative acetyltransferase, (GNAT) family0.0216 putative ABC transporter permease0.1335 ABC transporter ATP-binding protein0.1725 ABC transporter permease0.0531 putative outer membrane efflux protein0.2962 two-component system response regulator0.1262 putative two-component system sensor histidine kinase0.0029 putative transmembrane protein0.0015 glycoside transferase family 20.0770 putative acetyltransferase, GNAT family0.2014 ribosomal protein S6 modification protein-related protein0.0670 ABC transporter, permease protein0.2327 aspartate aminotransferase

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0.0255 conserved hypothetical protein0.0454 putative histidinol-phosphatase0.0017 ABC transporter ATP-binding protein0.2836 conserved hypothetical protein0.1456 conserved hypothetical protein0.0509 two-component system response regulator0.1750 two-component system sensor histidine kinase0.0535 conserved hypothetical protein with a conserved domain0.0233 hypothetical protein0.0057 quinoprotein amine dehydrogenase-like protein0.0222 quinonprotein alcohol dehydrogenase-like protein0.0000 putative cell surface protein0.1423 vitamin B12 receptor, outer membrane0.2697 conserved hypothetical protein, putative surface protein0.0502 conserved hypothetical protein0.0083 tyrosine phenol-lyase0.0000 conserved hypothetical protein0.0561 conserved hypothetical protein0.0547 siderophore (surfactin) biosynthesis regulatory protein0.2845 hemolysin-related protein, containing CBS domain0.0310 single-strand binding protein (SSB)0.1803 A/G-specific adenine glycosylase0.0642 DNA-binding protein HU0.1865 Ribonuclease G0.0080 major outer membrane protein OmpA0.0705 conserved hypothetical protein0.0041 integrase0.0001 hypothetical protein0.0760 outer membrane protein0.0081 hypothetical protein0.0259 conserved hypothetical protein

N/D hypothetical protein0.0084 integrase0.1410 conserved hypothetical protein0.0004 outer membrane protein OmpA0.0134 conserved hypothetical protein, putative surface protein0.0001 integrase0.1773 hypothetical protein0.1477 conserved hypothetical protein0.0697 replicative DNA helicase0.3127 conserved hypothetical protein0.0067 hypothetical protein0.0758 N-acetylmuramoyl-L-alanine amidase0.0754 putative transcriptional regulator

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0.0085 putative membrane protein0.1046 putative aureobasidin A resistance protein0.2842 CDP-diacylglycerol-inositol 3-phosphatidyltransferase0.2713 hypothetical protein0.1134 phosphatidylglycerophosphatase A0.2955 myo-inositol-1-phosphate synthase0.0487 putative outer membrane protein0.1766 two-component system sensor histidine kinase0.2109 two-component system response regulator0.0000 putative outer membrane protein OprM precursor0.0680 two-component system sensor histidine kinase0.0022 ABC transporter permease0.0012 putative ABC transporter permease component0.0000 conserved hypothetical protein0.0007 ABC transporter ATP-binding protein0.0000 ABC transporter permease0.0670 putative NADH dehydrogenase0.0000 hemagglutinin0.0233 cytidine deaminase0.0219 transcriptional regulator0.1940 putative transmembrane protein0.0160 putative pyridine nucleotide-disulfide oxidoreductase0.0760 putative ABC transporter ATP-binding protein0.0760 NADH pyrophosphatase, MutT family hydrolase0.2676 conserved hypothetical protein, putative regulatory protein with a cAMP-binding domain0.2429 acyltransferase0.1283 putative membrane-associated protein0.0000 phosphoglucomutase phosphomannomutase0.0298 putative secreted peptidase0.0274 putative petidase0.0047 Peptidase M1A and M12B0.0048 SusC homolog0.0058 SusD homolog0.0001 alanine dehydrogenase0.2025 2-nitropropane dioxygenase-like dioxygenase0.0918 conserved hypothetical protein0.0210 conserved hypothetical protein0.2672 conserved hypothetical protein0.0014 RNA polymerase ECF-type sigma factor0.0530 nicotinate-nucleotide pyrophosphorylase0.0663 conserved hypothetical protein0.0024 conserved hypothetical protein0.1707 Metal-dependent phosphohydrolase0.1222 putative GTP-cyclohydrolase protein

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0.2454 hypothetical protein0.2332 putative aluminum resistance protein0.3169 conserved hypothetical protein0.0019 conserved hypothetical protein0.2619 conserved hypothetical protein0.0590 TonB-dependent receptor-like protein0.1524 conserved hypothetical protein0.0008 RNA polymerase ECF-type sigma factor0.1018 porin-like protein0.0387 putative outer membrane protein precursor0.1397 putative dehydrogenase0.0118 putative Pirin family protein0.1033 pyridoxamine 5'-phosphate oxidase0.2209 putative metal dependent hydrolase0.2887 conserved hypothetical protein0.3098 lactoylglutathione lyase0.0770 hypothetical protein0.1674 putative methyltransferase0.1311 putative protein disulfide isomerase

N/D hypothetical protein0.0760 hypothetical protein0.1423 hypothetical protein0.2422 GCN5-related N-acetyltransferase0.1354 conserved hypothetical protein

N/D possible cell division protein0.0052 hypothetical protein0.1499 conserved hypothetical protein0.0000 putative ferrous iron transport protein0.0382 putative cell-cycle protein0.2763 putative ferredoxin0.0226 transcription termination factor rho0.1373 putative sulfatase yidJ0.0000 two-component system sensor histidine kinase0.0204 putative two-component system sensor histidine kinase0.0174 BexA, membrane protein0.1159 BexA, membrane proein0.0997 putative signal recognition protein

N/D transposaseN/D transposase

0.0029 conserved hypothetical protein0.0000 cytochrome c biogenesis protein0.0554 cytochrome C peroxidase0.0000 methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase0.1492 capsule biosynthesis protein capA

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0.0145 conserved hypothetical protein0.1561 DNA polymerase III subunit gamma/tau0.0431 conserved hypothetical protein0.0049 conserved hypothetical protein0.0002 Outer membrane chaperone Skp (OmpH)0.0000 conserved hypothetical protein0.2856 aminoacyl-histidine dipeptidase0.0233 endonuclease/exonuclease/phosphatase family0.0921 RNA polymerase ECF-type sigma factor0.0343 putative anti-sigma factor0.0194 SusC homolog0.0003 SusD homolog0.1766 beta-hexosaminidase precursor0.0502 N-acetylgalactosamine-6-sulfatase precursor0.0687 putative membrane protein0.0151 putative secreted sulfatase0.2430 putative exported fucosidase0.0226 beta-galactosidase0.1980 beta-hexosaminidase precursor0.2960 putative sulfatase yidJ0.2930 hypothetical protein0.0000 SusD homolog0.2609 SusC homolog0.2276 chitinase0.0770 mannose-1-phosphate guanyltransferase0.0472 putative aminoglycoside phosphotransferase0.1674 two-component system sensor histidine kinase/response regulator, hybrid (one-component system)0.2931 arylsulfatase precursor0.2676 hypothetical protein0.3106 conserved hypothetical protein0.0605 conserved hypothetical protein

N/D hypothetical proteinN/D N-acetylmuramoyl-L-alanine amidase

0.1373 conserved hypothetical protein0.1803 hypothetical protein0.1235 putative CPS biosynthesis glycosyltransferase0.0537 glycoside transferase family 20.0014 glycoside transferase family 20.0041 conserved hypothetical protein, putative integral membrane protein0.2130 glycoside transferase family 20.0000 glycoside transferase family 250.1165 putative teichoic acid biosynthesis protein F0.2793 pyrophosphorylase0.0210 lipopolysaccharide biosynthesis protein

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0.0233 Lipopolysaccharide biosynthesis protein0.0014 polysialic acid transport protein kpsD precursor

N/D conserved hypothetical proteinN/D putative transcriptional regulatorN/D integrase

0.0048 transaldolase0.0182 fructose-bisphosphate aldolase class I0.0616 phosphoglycerate mutase0.1682 two-component system sensor histidine kinase0.0158 putative molybdenum transport ATP-binding protein0.1634 pullulanase precursor0.0000 crossover junction endodeoxyribonuclease ruvC0.0000 conserved hypothetical protein0.0075 hydrolase, haloacid dehalogenase-like hydrolase0.1334 conserved hypothetical protein0.0133 conserved hypothetical protein, TonB-like protein0.3026 phenylalanyl-tRNA synthetase alpha chain0.0793 putative transmembrane transport protein0.1728 endonuclease III0.1079 phosphoglycerate kinase0.0145 thiamine biosynthesis protein, putative0.0522 hypothetical protein0.1415 conserved protein, with a conserved TPR domain0.1339 Maf protein0.0012 putative hydrolase0.0001 conserved hypothetical protein0.0025 conserved hypothetical protein0.2985 putative NADH dehydrogenase/NAD(P)H nitroreductase0.0781 putative carbonic anhydrase0.0760 SusD homolog0.3072 SusC homolog0.0475 conserved hypothetical protein0.0000 lactoylglutathione lyase and related protein0.0000 propionyl-CoA carboxylase beta chain0.0000 Sodium pump decarboxylase, gamma subunit0.0000 biotin carboxyl carrier protein (BCCP)0.0008 oxaloacetate decarboxylase beta chain0.0705 TPR domain-containing protein0.1171 fructose-bisphosphate aldolase0.0946 50S ribosomal protein L31 type B0.1002 periplasmic linker protein, putative multidrug resistance protein0.1153 transporter, AcrB/D/F family0.1211 outer membrane efflux protein0.0291 oxaloacetate decarboxylase beta chain

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0.0280 pyruvate carboxylase subunit B0.0502 putative oxaloacetate decarboxylase gamma chain0.1654 conserved hypothetical protein0.0642 conserved hypothetical protein0.0028 hypothetical protein0.0001 hypothetical protein0.2817 conserved hypothetical protein0.0797 hypothetical protein

N/D hypothetical protein0.0687 putative N-acetylmuramoyl-L-alanine amidase0.0894 putative nucleotidyltransferase0.2263 putative capsular polysaccharide biosynthesis glycosyltransferase0.1714 glycoside transferase family 20.2521 conserved hypothetical protein0.0681 conserved hypothetical protein0.0887 glycoside transferase family 40.1162 putative acylneuraminate cytidylyltransferase0.0009 sialic acid synthase (N-acetylneuraminate synthase)0.0684 putative polysaccharide biosynthesis protein0.0713 putative teichoic acid biosynthesis protein B precursor0.1157 putative lipopolysaccharide biosynthesis protein0.1940 putative 2-aminoethylphosphonate pyruvate aminotransferase0.2610 sulfopyruvate decarboxylase subunit beta0.1695 phosphoenolpyruvate phosphomutase precursor0.0357 putative glucose-1-P-cytidylyltransferase0.0003 putative protein involved in capsular polysaccharide biosynthesis0.1402 polysialic acid transport protein kpsD precursor0.1940 conserved hypothetical protein0.1760 putative transcriptional regulator

N/D integrase0.0495 putative transmembrane sensor0.0070 RNA polymerase ECF-type sigma factor0.1091 peptide chain release factor 3 (RF-3)0.0000 putative dTDP-4-dehydrorhamnose reductase0.0000 conserved hypothetical protein0.0406 amino acid exporter, putative0.0000 putative phosphoribosylformylglycinamidine synthase0.2664 two-component system sensor histidine kinase/response regulator, hybrid (one component system)0.0857 chromate transport protein0.0001 chromate transport protein0.0948 putative secreted protein0.0014 two-component system sensor histidine kinase0.1897 excinuclease ABC subunit A0.0435 conserved hypothetical protein

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0.0457 conserved hypothetical protein0.0075 carbon starvation protein A0.2214 hypothetical protein0.0063 S-layer protein0.0314 conserved hypothetical protein0.0000 conserved hypothetical protein, ATPase0.0000 pyruvate-flavodoxin oxidoreductase0.2539 hypothetical protein0.2359 glycine betaine-binding protein precursor0.2829 glycine betaine/L-proline transport system permease0.0061 Glycine betaine transport ATP-binding protein0.0507 conserved hypothetical protein0.2187 putative methylated-DNA methyltransferase0.0241 two-component system sensor histidine kinase/response regulator, hybrid (one component system)0.2352 putative exported 24-amino acid repeat protein

N/D transposase, invertase0.0000 fructokinase0.1188 glucose/galactose transporter0.0008 levanase precursor (2,6-beta-D-fructofuranosidase)0.2531 glycoside hydrolase family 320.2147 conserved hypothetical protein0.0288 SusD homolog0.0002 SusC homolog0.0758 Aldose 1-epimerase family protein0.0000 levanase precursor (2,6-beta-D-fructofuranosidase)0.0760 putative ribonucleoprotein-related protein0.0261 conserved hypothetical protein, transcription regulator-like protein0.0732 beta-galactosidase0.1732 putative alpha-1,2-mannosidase0.0203 putative transmembrane protein0.0977 putative cell surface protein0.0697 conserved hypothetical protein0.2658 SusD homolog0.0700 SusC homolog0.1738 Galactose-binding-like protein0.1113 beta-galactosidase0.2151 glycoside hydrolase family 950.0676 beta-glucosidase (gentiobiase)0.0537 sialic acid-specific 9-O-acetylesterase0.1048 periplasmic beta-glucosidase precursor0.0486 xylosidase/arabinosidase0.0308 putative phosphoesterase0.2164 cation/H+ antiporter0.1571 conserved hypothetical protein

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0.2754 putative outer membrane protein0.0069 putative lipoprotein0.0001 conserved hypothetical protein0.0948 conserved hypothetical protein0.2181 aminopeptidase C (bleomycin hydrolase)0.2641 conserved hypothetical protein, intergrase-like protein0.1474 outer membrane protein0.0000 putative cell surface protein0.0011 integrase protein0.0983 two-component system response regulator0.3015 putative two-component system sensor protein0.2938 conserved hypothetical protein, putative membrane protein0.0489 putative transcriptional regulator0.0084 hypothetical protein0.0019 putative vitamin B12 receptor precursor0.0663 putative two-component system sensor histidine kinase0.0000 two-component system sensor histidine kinase0.0015 two-component system sensor histidine kinase0.0691 conserved hypothetical protein0.0000 electron transfer flavoprotein beta-subunit0.0000 electron transfer flavoprotein alpha-subunit0.0000 acyl-CoA dehydrogenase0.0059 conserved protein, with rhomboid family domain0.0001 conserved hypothetical protein0.1511 conserved protein, with weak BamHI domain0.2276 GAF domain-containing protein0.0110 conserved hypothetical protein0.0007 putative chaperone DnAJ0.0525 conserved hypothetical protein, putative integral membrane protein0.2808 Bacterial surface antigen (D15)0.0803 low-specificity L-threonine aldolase0.0000 conserved hypothetical protein0.0157 RNA polymerase ECF-type sigma factor0.0000 conserved hypothetical protein0.0417 conserved hypothetical protein0.0887 pyruvate dehydrogenase

N/D transposaseN/D pyruvate dehydrogenase, cytochrome

0.0691 conserved hypothetical protein, putative membrane protein0.0003 conserved hypothetical protein, putative permease0.0143 conserved hypothetical protein0.2830 conserved hypothetical protein0.0433 transposase0.1662 conserved protein, with a weak D-galactarate dehydratase/altronate hydrolase domain

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0.0537 60 kDa chaperonin (groEL)0.0642 10 kDa chaperonin (groES)0.0408 conserved hypothetical protein0.0775 conserved hypothetical protein0.0291 two-component system sensor histidine kinase0.0442 putative hydrogenase0.0405 biotin synthase0.1056 thiamine biosynthesis protein ThiH0.3060 putative GTP-binding protein, putative GTPase0.1261 putative alanyl dipeptidyl peptidase0.2403 conserved hypothetical protein0.0076 histidyl-tRNA synthetase0.1064 neutral zinc metallopeptidase0.0995 alpha-L-fucosidase precursor0.0000 adenylosuccinate synthetase0.0000 transcriptional regulator, putative iron uptake regulation protein0.1241 conserved hypothetical protein0.0577 putative dipeptidyl-peptidase III0.2133 transcriptional regulator, AraC/XylS family0.2248 ATP-dependent DNA helicase recQ

N/D hypothetical protein0.2405 putative transmembrane acyltransferase protein0.1638 TPR-repeat-containing protein0.2538 cysteine synthase A0.2602 putative sulfatase0.1820 putative membrane-associated phospholipid phosphatase0.1981 putative methyl transferase0.0115 hypothetical protein0.0000 3-isopropylmalate dehydrogenase0.0232 2-isopropylmalate synthase0.0009 3-isopropylmalate dehydratase small subunit0.0003 3-isopropylmalate dehydratase large subunit0.0067 2-isopropylmalate synthase0.0014 hypothetical protein

N/D hypothetical proteinN/D putative methyltransferaseN/D putative fiber proteinN/D hypothetical proteinN/D hypothetical proteinN/D conserved hypothetical proteinN/D conserved hypothetical proteinN/D integrase

0.1054 putative alpha-glucosidase0.0549 periplasmic beta-glucosidase precursor

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0.0680 endo-arabinase0.2844 SusD homolog0.2256 SusC homolog0.0048 putative anti-sigma factor0.0257 RNA polymerase ECF-type sigma factor0.0472 putative alpha-1,2-mannosidase0.1620 protease IV0.1713 tetraacyldisaccharide 4'-kinase0.0000 purine nucleoside phosphorylase I0.0000 putative thiamine-monophosphate kinase0.0025 putative alpha-1,6-mannanase0.0095 cold shock protein, putative DNA-binding protein0.0078 putative ATP-dependent RNA helicase0.0396 oxidoreductase, 2-nitropropane dioxygenase family0.0812 putative RNA-binding protein rbpA0.0467 transcriptional regulator, LuxR family0.0059 conserved hypothetical protein0.0070 ATP-dependent DNA helicase replicase

N/D hypothetical proteinN/D integraseN/D putative receptor

0.0806 TPR-repeat-containing protein0.0009 conserved hypothetical protein0.0004 putative cell surface antigen0.0077 putative lemA protein0.0080 conserved hypothetical protein, galanin-like protein0.1010 conserved hypothetical protein0.0004 BexA, putative cation effux pump0.0680 lysine-sensitive aspartokinase III0.0625 pyrroline-5-carboxylate reductase

N/D hypothetical protein0.1996 transcriptional regulator, AraC-type0.1803 conserved hypothetical protein0.0683 transcriptional regulator0.0456 putative RNA polymerase sigma factor RpoS0.2747 conserved hypothetical protein0.0765 hypothetical protein0.0001 conserved hypothetical protein, HIV negative factor Nef-like protein0.2078 7-alpha-hydroxysteroid dehydrogenase0.0012 hypothetical protein0.0578 nicotinate phosphoribosyltransferase

N/D thioredoxin-like protein, putative thioredoxin0.0153 pyruvate carboxylase subunit A0.1648 putative methylmalonyl-CoA decarboxylase biotin

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0.0860 propionyl-CoA carboxylase beta chain0.0324 choline-sulfatase0.1621 putative transmembrane protein0.0153 hypothetical protein0.0143 putative cell wall biosynthesis related protein0.1710 putative N-acetylmuramoyl-L-alanine amidase0.0149 O-acetylhomoserine (thiol)-lyase0.0024 putative metal-dependent hydrolase0.0598 conserved hypothetical protein0.0010 conserved hypothetical protein0.0670 conserved hypothetical protein0.0758 transposase0.0433 transposase

N/D possible DNA-binding protein0.2373 putative type IIS restriction/modification enzyme0.1695 putative transposase0.2836 transposase0.0586 Cyclin-like protein0.0018 hypothetical protein0.0043 hypothetical protein0.0416 hypothetical protein0.2666 putative lipoprotein0.2988 putative outer membrane receptor0.1377 conserved hypothetical protein0.0797 hypothetical protein

N/D hypothetical proteinN/D hypothetical protein

0.0240 putative transposase0.0765 conserved protein found in conjugate transposon0.2217 conserved hypothetical protein

N/D conserved hypothetical proteinN/D hypothetical protein

0.1457 conserved hypothetical protein0.0760 Fe3+ ABC transporter, ATP-binding protein0.1987 Fe3+ ABC transporter, permease protein0.0290 Fe3+ ABC transporter, periplasmic iron-binding protein0.1210 putative TonB-linked outer membrane receptor0.2327 putative surface layer protein0.3030 putative cell wall biogenesis protein0.2451 putative cell surface protein0.1113 conserved hypothetical protein0.0912 hypothetical protein0.0797 DNA breaking-rejoining enzyme, catalytic core0.1767 integrase

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0.0760 transposase0.0525 hypothetical protein0.2676 putative transcriptional regulator

N/D bacterial regulatory protein, Te-like protein0.3098 multidrug efflux pump channel protein0.1973 multidrug resistance protein, AcrB/AcrD family0.2078 multidrug efflux protein0.2161 transcriptional regulator0.1972 NADP-dependent malate dehydrogenase0.1262 glutamate dehydrogenase0.0978 catalase0.0672 phosphoenolpyruvate synthase/pyruvate phosphate dikinase0.3115 NAD-specific glutamate dehydrogenase0.0001 metallopeptidase family M24, putative Xaa-Pro dipeptidase0.2968 tRNA nucleotidyltransferase0.0000 hypothetical protein0.0960 conserved hypothetical protein0.0000 Holliday junction DNA helicase ruvA0.2842 Meso-diaminopimelate D-dehydrogenase0.0210 transposase0.0402 hypothetical protein0.0797 hypothetical protein0.2268 hemolysin III0.1833 transcriptional regulator0.3138 hypothetical protein0.0781 putative ribose 5-phosphate isomerase0.0781 hypothetical protein0.0781 conserved hypothetical protein0.1823 conserved hypothetical protein0.0715 Histone-like bacterial DNA-binding protein0.0781 N-acetylmuramoyl-L-alanine amidase0.2658 hypothetical protein0.0913 putative cell wall-associated protein precursor0.0275 conserved hypothetical protein0.2256 hypothetical protein

N/D transposase0.0742 hypothetical protein0.2661 anaerobic ribonucleoside-triphosphate reductase0.1001 anaerobic ribonucleoside-triphosphate reductase activating protein0.0047 putative transport protein0.2243 membrane-associated zinc metalloprotease0.0670 1-deoxy-D-xylulose 5-phosphate reductoisomerase0.1940 putative membrane peptidase0.0680 RimM protein

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0.0670 UDP-N-acetylglucosamine 1-carboxyvinyltransferaseN/D conserved hypothetical protein

0.1529 conserved hypothetical protein, putative glycoprotease0.0797 YicC-like family protein0.0676 guanylate kinase (GMP kinase)0.0671 hypothetical protein0.1339 putative nicotinate-nucleotide adenylyltransferase0.2048 conserved hypothetical protein, putative ATPase0.0092 putative phosphohydrolase0.1940 1,4-dihydroxy-2-naphthoate octaprenyltransferase

N/D putative menaquinone biosynthesis protein0.2513 dTDP-glucose 4,6-dehydratase0.0760 glucose-1-phosphate thymidylyltransferase0.0000 conserved hypothetical protein0.2676 polyphosphate kinase0.1974 putative phosphate/sulphate permease0.2676 conserved hypothetical protein, putative non-specific DNA-binding protein0.0765 hypothetical protein0.0027 two-component system sensor histidine kinase

N/D conserved hypothetical protein0.0765 hypothetical protein0.0039 endonuclease0.0000 N-acetylmuramoyl-L-alanine amidase0.2158 DnaD domain-like protein

N/D conserved hypothetical protein0.0464 conserved hypothetical protein0.0638 hypothetical protein0.0004 SusC homolog0.0000 SusD homolog0.0000 two-component system response regulator0.0521 putative ABC transporter ATP-binding protein0.0069 conserved hypothetical protein0.0181 conserved hypothetical protein0.1019 cation efflux system protein0.3138 cation efflux system protein, AcrB/AcrD/AcrF family protein0.0000 putative outer membrane efflux protein0.0176 hypothetical protein0.0385 tRNA and rRNA cytosine-C5-methylase0.2917 conserved hypothetical protein0.0001 RNA polymerase ECF-type sigma factor0.1437 hypothetical protein0.2621 putative cardiolipin synthetase0.1713 thymidylate synthase

N/D dihydrofolate reductase

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0.0000 transcriptional regulator0.0073 putative lipoprotein0.0104 acetyltransferase-like, GNAT family0.0000 putative membrane protein0.0000 conserved hypothetical protein0.0000 conserved hypothetical protein0.0000 putative biopolymer transport protein0.2612 hydrolase, putative0.0091 conserved hypothetical protein0.0000 putative isoprenyl synthetase0.0000 TonB0.0452 cytidylate kinase0.0581 penicillin tolerance protein LytB0.0000 6-phosphofructokinase0.0044 conserved hypothetical protein, putative iron uptake factor0.0536 conserved hypothetical protein0.0762 putative TonB-linked outer membrane receptor0.0760 putative oxidoreductase0.0132 putative NADH:flavin oxidoreductase0.2368 3-oxo-5-alpha-steroid 4-dehydrogenase0.1039 GCN5-related N-acetyltransferase0.0065 citrate synthase0.0178 isocitrate dehydrogenase (NADP)0.0192 aconitate hydratase0.2787 putative helicase0.0000 ketol-acid reductoisomerase0.0002 acyl-ACP thioesterase0.0283 acetohydroxyacid synthase small subunit0.0023 acetolactate synthase large subunit0.0090 dihydroxy-acid dehydratase0.1037 peptidyl-prolyl cis-trans isomerase0.0086 conserved hypothetical protein, putative inner membrane protein0.1330 conserved hypothetical protein0.0018 conserved hypothetical protein0.1529 conserved hypothetical protein0.0000 chorismate synthase0.0486 putative succinyl-diaminopimelate desuccinylase0.0783 choloylglycine hydrolase0.1185 conserved hypothetical protein0.0074 hypothetical protein0.2934 DNA topoisomerase III0.0000 methylmalonyl-CoA mutase large subunit0.0000 methylmalonyl-CoA mutase small subunit0.0289 putative membrane protein

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0.2080 putative cytidylate kinase0.0311 TonB-dependent receptor0.0750 putative surface layer protein0.1217 putative transcriptional regulator0.2888 Six-hairpin glycosidase0.0065 Fe3+ ABC transporter, periplasmic iron-binding protein0.1820 Fe3+ ABC transporter, permease0.1484 putative ABC transporter, ATP-binding protein0.1721 putative transmembrane cation efflux protein0.2260 putative cAMP-binding domain, regulatory protein0.0001 transcriptional regulator0.0688 ROK family member transcriptional repressor0.0680 putative alpha-1,2-mannosidase0.0101 putative transmembrane hexose transporter0.2856 SusC homolog0.3158 SusD homolog0.0000 Galactose-binding-like protein0.0212 putative chitobiase0.0997 putative alpha-1,2-mannosidase0.0488 beta-glucanase precursor0.0000 glycosyl hydrolases 38-like protein0.0532 conserved hypothetical DNA-binding protein0.1588 hypothetical protein0.1503 GCN5-related N-acetyltransferase-like protein0.3108 outer membrane protein, putative0.1020 transporter, AcrB/D/F family0.2631 transmembrane protein precursor, possibly involved in transport0.1064 transcriptional regulator0.0530 putative Na+-driven multidrug efflux pump0.1228 lysyl-tRNA synthetase0.0667 glycerol-3-phosphate dehydrogenase0.2676 glucose-6-phosphate isomerase0.1728 putative lipoprotein0.0018 hypothetical protein0.2502 putative beta-phosphoglucomutase0.0298 fucose kinase0.0150 aspartate--ammonia ligase0.1531 uracil-DNA glycosylase

N/D hypothetical protein0.2299 Cyclic nucleotide-binding protein0.3033 conserved hypothetical protein0.1477 putative HD superfamily hydrolase0.2724 putative lipoprotein0.1706 putative purple acid phosphatase

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N/D transposaseN/D conserved hypothetical protein

0.1604 conserved hypothetical protein0.2518 putative sodium-dependent transporter0.1175 putative N-acetylmuramoyl-L-alanine amidase amiA0.2602 conserved hypothetical protein, with a conserved domain0.2234 chromosomal replication initiator protein dnaA0.0378 putative oxidoreductase0.0000 ribonucleoside-diphosphate reductase alpha chain0.0002 4-alpha-glucanotransferase0.0760 O-acetyl transferase0.1128 glycoside transferase family 4

N/D dihydroneopterin aldolase0.0781 methylglyoxal synthase

N/D glycoside transferase family 20.0291 putative acetyltransferase0.1448 putative Fe-S oxidoreductase0.0430 putative long-chain-fatty-acid--CoA ligase0.0429 hypothetical protein0.1222 putative sugar phosphate isomerase/epimerase0.2412 probable secreted glycosyl hydrolase0.0451 putative dehydrogenase0.0064 putative oxidoreductase0.0001 putative regulatory protein0.0000 50S ribosomal protein L90.0649 30S ribosomal protein S180.2676 30S ribosomal protein S60.2063 MarR family transcriptional regulator0.1319 two-component system response regulator0.0770 two-component system sensor histidine kinase0.1455 elongation factor G0.3143 coproporphyrinogen III oxidase0.1763 RNA polymerase ECF-type sigma factor0.0001 conserved hypothetical protein0.2373 putative anti-sigma factor0.0145 SusC homolog0.0065 SusD homolog0.1095 ABC transporter ATP-binding protein0.0059 hypothetical protein0.1061 conserved hypothetical protein0.1988 putative membrane protein0.2105 conserved hypothetical protein0.0321 putative DNA mismatch repair protein0.0566 putative haloacid dehalogenase-like family hydrolase

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0.2676 transcriptional regulator0.0797 conserved hypothetical protein0.2692 conserved hypothetical protein

N/D RNA polymerase ECF-type sigma factor0.0000 hypothetical protein0.0000 3-phosphoshikimate 1-carboxyvinyltransferase0.2375 putative cAMP-binding domain-containing regulatory protein0.0832 putative oxidoreductase0.1295 aminopeptidase0.1082 beta-galactosidase0.0002 beta-galactosidase0.1767 putative lipoprotein0.2554 Peptidase S26A, signal peptidase0.0660 sialidase precursor, exo-alpha-sialidase0.1896 SusD homolog0.0624 SusC homolog0.0203 putative anti-sigma factor0.0087 RNA polymerase ECF-type sigma factor0.0496 alpha-1,2-mannosidase0.2093 conserved hypothetical protein0.3072 SusD homolog0.2512 putative outer membrane protein, probably involved in nutrient binding0.0915 Concanavalin A-like lectin/glucanase0.3175 putative transmembrane protein0.1972 protein with phospholipase A2, active site0.1311 Zinc ABC transporter, permease0.0651 putative ATPase/GTPase0.0868 putative transmembrane protein0.0431 putative nucleotidyltransferase0.1704 conserved hypothetical protein0.0107 putative transmembrane protein0.0041 magnesium chelatase, subunit I, putative ATPase0.0003 conserved hypothetical protein0.0003 conserved hypothetical protein0.0308 putative transmembrane protein0.0115 conserved hypothetical protein, putative integral membrane protein0.2563 hypothetical protein0.1561 hypothetical protein0.2403 hypothetical protein0.2708 hypothetical protein0.1428 hypothetical protein

N/D transposase0.2953 TPR-repeat-containing protein0.0676 RDD family-like membrane protein

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0.3097 Histone-like bacterial DNA-binding protein0.3065 transcriptional regulator0.0000 conserved hypothetical protein0.1629 conserved hypothetical protein0.0000 thioredoxin (thioredoxin M)0.2125 DNA polymerase III alpha subunit0.2962 phosphatidylserine decarboxylase0.0561 CDP-diacylglycerol--serine O-phosphatidyltransferase0.0042 conserved hypothetical protein0.0000 putative cytosine/adenosine deaminase0.0013 hypothetical protein0.0765 endonuclease-like protein

N/D putative MmcQ-like protein0.1454 putative biotin--(acetyl-CoA carboxylase) synthetase0.0561 carboxyl-terminal protease0.0880 TPR domain-containing protein0.0029 DNA-damage-inducible protein F0.0439 uridylate kinase0.2062 Protein prenyltransferase0.3140 hypothetical protein0.0000 hypothetical protein0.2598 hypothetical protein0.0841 putative ryanodine receptor0.0000 putative integral membrane protein0.2676 ribosome recycling factor (ribosome releasing factor)0.0033 putative GTPase0.0099 putative membrane fusion protein precursor0.1591 multidrug efflux membrane fusion protein0.1268 putative outer membrane protein TolC0.0316 putative pectate lyase0.1674 probable membrane protein0.2357 fumarate hydratase class I, anaerobic0.0012 lipoprotein, putative0.2220 GTP-binding protein0.0397 putative lipoprotein0.0187 outer membrane protein Omp1210.0181 hypothetical protein0.2675 hypothetical protein0.1120 putative lipoprotein0.0676 outer membrane protein Omp1210.0670 hypothetical protein0.0202 hypothetical protein0.0103 integrase protein0.0355 SusC homolog

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0.0486 SusD homolog0.2214 integral membrane protein (MarC family)0.0025 haloacid dehalogenase-like hydrolase0.2904 conserved hypothetical protein0.3158 methyltransferase0.1919 hypothetical protein0.0549 thymidine kinase0.0164 putative permease0.3098 transposase0.1803 lipoprotein, putative0.0869 putative ribose phosphate pyrophosphokinase0.2445 conserved hypothetical protein

N/D hypothetical protein0.0000 conserved hypothetical protein

N/D conserved hypothetical proteinN/D conserved hypothetical protein

0.1844 hypothetical protein0.0680 conserved hypothetical protein0.0111 conserved protein found in conjugate transposon0.0414 conserved protein found in conjugate transposon0.0072 conserved protein found in conjugate transposon0.1541 conserved protein found in conjugate transposon0.2925 hypothetical protein0.0780 conserved protein found in conjugate transposon0.0586 conserved protein found in conjugate transposon

N/D conserved protein found in conjugate transposon0.0586 hypothetical protein0.0510 conserved protein found in conjugate transposon0.1705 putative reverse transcriptase0.0454 conserved protein found in conjugate transposon0.0558 conserved protein found in conjugate transposon0.0000 conserved protein found in conjugate transposon0.0000 conserved protein found in conjugate transposon

N/D conserved protein found in conjugate transposon0.2962 conserved protein found in conjugate transposon0.0174 hypothetical protein0.0302 putative mobilization protein0.0032 putative mobilization protein0.0053 tetracycline resistance element mobilization regulatory protein rteC0.2419 transcriptional regulator

N/D hypothetical protein0.2233 putative transcriptional regulator0.1668 conserved hypothetical protein0.0004 conserved hypothetical protein

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0.1902 Retron-type reverse transcriptase0.0724 hypothetical protein0.0754 hypothetical protein0.1166 conserved hypothetical protein0.0797 conserved hypothetical protein0.0388 hypothetical protein0.1480 conserved hypothetical protein0.2181 transcription regulator

N/D putative integrase0.2593 putative integrase0.0760 conserved hypothetical protein0.0569 DNA topoisomerase III0.1940 conserved hypothetical protein0.1408 putative DNA methylase0.0598 conserved hypothetical protein0.0587 conserved hypothetical protein0.0506 conserved hypothetical protein0.1171 putative Toll-Interleukin receptor0.0086 conserved hypothetical protein, with a calcineurin-like phosphoesterase domain0.1940 Putative DNA binding protein0.1872 Toprim domain protein

N/D Putative DNA binding protein0.1940 integrase protein0.2962 Putative DNA binding protein0.2676 conserved hypothetical protein0.2923 putative transcriptional regulator0.0520 conserved hypothetical protein0.0195 conserved hypothetical protein0.0369 conserved hypothetical protein0.1630 transcription regulator0.0029 conserved hypothetical protein

N/D hypothetical protein0.0463 hypothetical protein0.2260 iron-sulfur cluster-binding protein0.2836 transposase0.2287 conserved hypothetical protein, IS related0.0059 transposase

N/D conserved hypothetical protein, IS relatedN/D conserved hypothetical protein, IS relatedN/D transposase

0.0197 conserved hypothetical protein0.0719 conserved hypothetical protein0.0842 site-specific DNA-methyltransferase0.0028 transcriptional regulator, AraC family

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0.0781 conserved hypothetical protein0.0346 hypothetical protein0.0018 formamidopyrimidine-DNA glycosylase0.0754 transcriptional regulator0.2080 hypothetical protein with Helix-turn-helix motif0.1472 SusC homolog0.0524 SusD homolog0.0089 SusC homolog0.1622 SusD homolog0.2965 putative regulatory protein0.0000 acyltransferase0.1171 conserved hypothetical protein0.0202 putative lipoprotein0.0733 conserved hypothetical protein0.2550 putative protease/amidase0.0696 transcriptional regulator0.0011 conserved hypothetical protein0.0544 conserved hypothetical protein

N/D hypothetical protein0.1555 conserved hypothetical protein0.0447 cation efflux pump0.2884 endo-polygalacturonase0.0000 hypothetical protein0.1278 putative oxidoreductase

N/D putative acetyltransferase0.0150 putative cardiolipin synthetase0.0797 RNA polymerase ECF-type sigma factor0.0608 acetyltransferase0.0505 conserved hypothetical protein0.3112 AsnC family transcriptional regulator0.0402 O-acetylhomoserine (thiol)-lyase0.0339 conserved hypothetical protein0.1222 putative transport protein0.0127 putative TonB-dependent transmembrane receptor0.0014 two-component system sensor histidine kinase/response regulator, hybrid (one component system)0.0846 NHL repeat-containing protein0.0018 SusC homolog0.0000 SusD homolog0.1888 hypothetical protein0.2268 putative membrane transporter involved in nicotinamide mononucleotide transport0.0902 Thiamin pyrophosphokinase-like, catalytic domain

N/D hypothetical proteinN/D transposase

0.1339 DNA-3-methyladenine glycosylase I

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0.0863 threonine synthase0.1102 phosphoglycerate mutase0.0000 aspartokinase/homoserine dehydrogenase0.0537 L-asparaginase I0.0000 conserved hypothetical protein0.0175 putative DNA repair protein0.0233 NAD-utilizing dehydrogenase0.2664 luxR family transcriptional regulator0.0001 putative TonB-dependent outer membrane protein0.0357 putative acetyltransferase0.0105 conserved hypothetical protein0.2225 putative collagenase0.0000 homoserine O-succinyltransferase0.0000 ferredoxin0.0000 aspartate aminotransferase0.1285 GTP cyclohydrolase II0.1474 putative permease0.0014 conserved hypothetical protein0.1205 putative GMP synthase, glutamine-hydrolyzing0.1019 two-component system histidine kinase, FrrD0.0472 FrrC, osmosensitive K+ channel histidine kinase0.0017 conserved hypothetical protein0.0797 K+-transporting ATPase C chain0.2890 K+-transporting ATPase B chain0.1472 K+-transporting ATPase A chain

N/D hypothetical proteinN/D transposaseN/D hypothetical protein

0.1126 hypothetical protein0.0676 hexokinase type III0.0203 conserved hypothetical protein0.1606 beta-mannosidase precursor0.0010 two-component system response regulator0.0764 pyridine nucleotide-disulphide oxidoreductase0.0830 MarR family transcriptional regulator0.2036 putative secreted tripeptidyl aminopeptidase0.0873 conserved hypothetical protein0.2458 conserved hypothetical protein0.0139 beta-N-acetylglucosaminidase0.0023 5'-nucleotidase precursor0.0770 putative 5-nucleotidase/2,3-cyclic phosphodiesterase0.2710 major outer membrane protein OmpA0.0142 hypothetical protein0.0018 hypothetical protein

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N/D putative integrase0.0690 integrase0.3095 integrase0.0797 Putative DNA binding protein0.1765 hypothetical protein0.0098 conserved hypothetical protein0.0046 putative pyrogenic exotoxin B0.0000 hypothetical protein0.0464 hypothetical protein0.0172 hypothetical protein0.0000 reverse transcriptase/maturase family protein0.0758 putative reverse transcriptase/maturase0.2980 putative purple acid phosphatase0.0010 putative pyridine nucleotide-disulphide oxidoreductase0.0011 beta-hexosaminidase precursor0.0876 SusD homolog0.0617 SusC homolog0.0691 putative anti-sigma factor0.1423 RNA polymerase ECF-type sigma factor0.0670 hypothetical protein0.2470 conserved hypothetical protein0.0742 conserved hypothetical protein0.0783 hypothetical protein0.2470 Putative DNA binding protein

N/D integrase0.2214 putative outer membrane protein

N/D putative outer membrane protein0.0730 hypothetical protein0.2112 conserved hypothetical protein0.1440 cytochrome c biogenesis protein ccsA0.0697 putative translation initiation inhibitor0.0012 hypothetical protein0.0000 conserved hypothetical protein0.2633 thiol oxidoreductase0.0166 iron-regulated protein A precursor0.0975 Aminotransferase, class IV0.2244 hypothetical protein0.2607 transcriptional regulator

N/D hypothetical protein0.0041 putative integrase0.0544 major outer membrane protein OmpA0.0411 hypothetical protein

N/D hypothetical protein0.0403 integrase

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0.0000 50S ribosomal protein L190.3097 hypothetical protein0.0000 hypothetical protein0.1974 RNA polymerase ECF-type sigma factor0.0587 ROK family transcriptional repressor, with glucokinase domain0.0296 ABC transporter, ATP-binding protein0.3146 ABC transporter, putative permease0.1479 putative ABC transporter, ATP-binding protein0.0074 membrane fusion efflux protein0.0324 putative outer membrane efflux protein0.0025 peptide methionine sulfoxide reductase msrA/msrB0.0255 conserved hypothetical protein0.0087 penicillin-binding protein0.0890 conserved hypothetical protein0.0090 conserved hypothetical protein0.0007 conserved hypothetical protein0.0239 conserved hypothetical protein0.2715 hypothetical protein0.1360 conserved hypothetical protein0.0298 conserved hypothetical protein0.0074 putative transcriptional regulator0.1529 malate dehydrogenase0.1098 putative transcription regulator0.0017 cation-transporting ATPase, P-type, putative zinc-transporting ATPase0.1743 conserved hypothetical protein0.2916 hypothetical protein0.0175 hypothetical protein0.0001 conserved hypothetical protein0.0208 GcpE, 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase0.2438 phosphoribosylaminoimidazole carboxylase0.0586 putative glycine cleavage system H protein0.0029 Phosphoesterase, PA-phosphatase0.0364 RNA polymerase sigma-540.1074 Xaa-Pro aminopeptidase0.0942 alpha-rhamnosidase0.3127 alpha-rhamnosidase0.0923 cephalosporin-C deacetylase0.0537 hypothetical protein0.0285 uridine kinase (uridine monophosphokinase)0.0052 putative Na+-dependent phosphate transporter0.0016 conserved hypothetical protein0.0017 conserved hypothetical protein, with a conserved domain0.0853 SusC homolog0.0082 SusD homolog

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0.0724 hypothetical proteinN/D Histone-like bacterial DNA-binding protein

0.1567 conserved hypothetical protein0.0881 hypothetical protein0.2826 hypothetical protein0.0001 conserved hypothetical protein, histone-like family0.0651 rubredoxin0.0039 two-component system sensor histidine kinase0.2469 putative calcium-transporting ATPase0.0705 putative haloacid dehalogenase-like hydrolase0.1837 riboflavin biosynthesis protein ribF, putative riboflavin kinase0.0001 putative metal-dependent membrane protease0.0210 conserved hypothetical protein0.0481 transcriptional regulator0.0660 Fe-S metabolism associated SufE0.2495 leucine aminopeptidase precursor0.0143 putative carboxypeptidase0.1446 beta-glucanase precursor0.0072 phosphate butyryltransferase0.0006 putative butyrate kinase0.2682 conserved hypothetical protein0.2130 putative DNA-binding protein0.0317 hypothetical protein

N/D conserved hypothetical proteinN/D transposaseN/D transposase

0.0000 SusD homolog0.1946 SusC homolog0.3149 putative anti-sigma factor0.0663 putative RNA polymerase ECF-type sigma factor0.0000 polyribonucleotide nucleotidyltransferase0.0479 conserved hypothetical protein0.0000 transcription elongation factor greA0.2911 HIT family protein0.0040 putative permease0.0019 putative sugar transporter0.1196 RNA polymerase ECF-type sigma factor0.0028 glutamate decarboxylase0.2320 putative glutaminase0.0663 putative potassium channel subunit0.0003 glutamate/gamma-aminobutyrate anti-porter0.0172 two-component system sensor histidine kinase0.1940 hypothetical protein0.2429 transposase

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0.0670 Peptidase, trypsin-like serine and cysteine0.0678 Beta-lactamase-like protein0.0091 conserved hypothetical protein0.1940 hypothetical protein0.2400 hypothetical protein

N/D conserved hypothetical protein0.0007 hypothetical protein0.2412 hypothetical protein0.0001 hypothetical protein

N/D hypothetical protein0.0000 hypothetical protein0.1974 conserved hypothetical protein0.0676 type I restriction enzyme, M subunit

N/D hypothetical protein0.2676 hypothetical protein0.3097 hypothetical protein0.2641 conserved protein found in conjugate transposon0.0009 conserved protein found in conjugate transposon0.0529 conserved protein found in conjugate transposon0.0287 conserved protein found in conjugate transposon0.0780 hypothetical protein0.0781 conserved protein found in conjugate transposon0.2382 conserved protein found in conjugate transposon0.1940 conserved protein found in conjugate transposon0.1940 conserved protein found in conjugate transposon0.0003 putative maturase/reverse transcriptase0.0510 conserved protein found in conjugate transposon0.0019 conserved protein found in conjugate transposon0.1514 hypothetical protein0.2347 conserved hypothetical protein0.0055 hypothetical protein0.0758 conserved hypothetical protein0.0046 conserved protein found in conjugate transposon0.0195 hypothetical protein0.0676 hypothetical protein0.0409 conserved hypothetical protein0.3189 putative mobilization protein0.0007 putative mobilization protein0.0161 reverse transcriptase0.0690 hypothetical protein0.1090 reverse transcriptase0.3108 two-component system response regulator0.1083 two-component system sensor histidine kinase0.2300 alpha-glucosidase

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0.0394 putative O-antigen related protein0.0536 alpha-glucuronidase0.1162 putative alpha-1,6-mannanase0.0254 hypothetical protein0.0442 SusD homolog0.0627 SusC homolog0.3106 putative cell surface protein, have conserved domain0.0053 two-component system sensor histidine kinase/response regulator, hybrid (one-component system)0.1788 putative alpha-1,2-mannosidase0.1936 conserved hypothetical protein with endonuclease/exonuclease/phosphatase family domain0.1117 glycoside hydrolase family 730.0441 conserved hypothetical protein0.0288 hypothetical protein0.0449 putative integrase/recombinase0.0252 putative integrase/recombinase0.1937 DNA breaking-rejoining enzyme, catalytic core

N/D hypothetical protein0.0963 hypothetical protein0.0773 integrase-like protein0.0026 hypothetical protein0.2676 hypothetical protein0.1402 conserved hypothetical protein

N/D conserved hypothetical protein0.0376 DNA topoisomerase I

N/D conserved hypothetical protein0.0602 conserved hypothetical protein0.2234 Peptidase M, neutral zinc metallopeptidase, zinc-binding site0.0091 conserved hypothetical protein0.1940 ThiF family protein, ubiquitin-activating enzyme0.1940 conserved hypothetical protein0.2360 bacterial regulatory protein, Me-like protein0.0765 Putative DNA binding protein0.2401 Putative DNA binding protein0.0624 transposase0.2045 hypothetical protein0.0311 ATPase, F complex, subunit A0.2079 putative lipoprotein0.0389 hypothetical protein0.0561 conserved hypothetical protein0.0012 FimX-like protein0.0094 hypothetical protein0.0344 alpha-galactosidase precursor0.0072 tetratricopeptide repeat family protein0.0000 putative phosphate ABC transporter, phosphate-binding component

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0.0023 TonB0.0649 conserved hypothetical protein0.2676 conserved hypothetical protein0.3121 MotA/TolQ/ExbB proton channel0.1064 conserved hypothetical protein

N/D hypothetical proteinN/D hypothetical proteinN/D hypothetical proteinN/D transposase

0.0099 hypothetical protein0.2217 conserved hypothetical protein0.0143 hypothetical protein0.2118 hypothetical protein0.0001 putative ion-channel protein, putative oxidoreductase0.0015 beta-galactosidase0.3116 alginate O-acetylation protein0.2825 putative periplasmic protein0.0755 putative periplasmic protein0.2827 hypothetical protein0.2025 conserved hypothetical protein0.1056 putative cation efflux transporter0.0484 cation efflux system protein0.0355 outer membrane efflux protein0.2614 putative TetR transcriptional regulator0.1799 histidine ammonia-lyase0.0210 methenyltetrahydrofolate cyclohydrolase0.0111 imidazolonepropionase0.0010 formiminotransferase-cyclodeaminase0.1774 putative urocanate hydratase0.0498 conserved hypothetical protein0.2836 hypothetical protein0.0005 DNA mismatch repair protein mutS0.2983 conserved hypothetical protein0.2438 conserved hypothetical protein0.0489 50S ribosomal protein L170.0286 DNA-directed RNA polymerase alpha chain0.1689 30S ribosomal protein S40.0625 30S ribosomal protein S110.2250 30S ribosomal protein S130.0781 translation initiation factor IF-10.1104 methionine aminopeptidase0.0306 preprotein translocase SecY subunit0.0724 50S ribosomal protein L15

N/D 50S ribosomal protein L30

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0.1054 30S ribosomal protein S50.1940 50S ribosomal protein L180.0770 50S ribosomal protein L60.0781 30S ribosomal protein S8

N/D chloroplast-like 30S ribosomal protein S140.0584 50S ribosomal protein L50.0593 50S ribosomal protein L240.0590 50S ribosomal protein L140.0742 30S ribosomal protein S170.0587 50S ribosomal protein L29

N/D 50S ribosomal protein L160.1833 30S ribosomal protein S30.0649 50S ribosomal protein L220.3112 30S ribosomal protein S190.2429 50S ribosomal protein L20.0504 50S ribosomal protein L230.0306 50S ribosomal protein L40.0742 50S ribosomal protein L3

N/D 30S ribosomal protein S100.0307 elongation factor G0.0640 30S ribosomal protein S70.2412 30S ribosomal protein S120.0819 conserved hypothetical protein0.0270 DNA-directed RNA polymerase beta' chain0.0896 DNA-directed RNA polymerase beta chain

N/D 50S ribosomal protein L7/L120.0760 ribosomal protein L100.0760 50S ribosomal protein L10.0655 50S ribosomal protein L11

N/D transcription anti-termination protein0.0372 elongation factor Tu0.1821 sigma-54 modulation protein0.0000 integrase, site-specific recombinase0.0048 putative aminopeptidase0.1371 acetyltransferase0.1976 thiol:disulfide interchange protein0.0233 thiol:disulfide interchange protein tlpA0.2438 3-deoxy-D-manno-octulosonic-acid transferase0.0543 glutamyl-tRNA synthetase0.2225 putative membrane-associated HD superfamily hydrolase0.0556 putative protein-tyrosine-phosphatase0.0185 neuramindase-like protein0.0286 primosomal protein N' (replication factor Y)0.0845 putative transmembrane protein

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0.1803 conserved hypothetical protein0.1451 aspartate ammonia-lyase0.0033 anaerobic C4-dicarboxylate transporter dcuB0.0013 L-asparaginase II precursor0.0001 conserved hypothetical protein

N/D conserved hypothetical protein0.0474 putative Cobalamin adenosyltransferase0.2566 conserved hypothetical protein, O-methyltransferase-like protein0.3023 TonB

N/D transposase0.0139 hypothetical protein0.2940 hypothetical protein0.1529 hypothetical protein0.0405 hypothetical protein0.0021 hypothetical protein0.1820 putative serine/threonine-protein kinase pknB0.1940 conserved hypothetical protein, serine/threonine kinase pknB-like protein0.0132 putative serine/threonine-protein kinase pknB0.2438 putative protein phosphatase0.0648 Forkhead-associated protein-like protein0.2419 putative adenylate cyclase0.2593 putative helicase0.0781 hypothetical protein0.1228 conserved hypothetical protein0.2606 RNA polymerase ECF-type sigma factor0.0036 3-demethylubiquinone-9 3-methyltransferase0.1586 conserved hypothetical protein, putative membrane-associated protein0.0692 putative mannose-1-phosphate guanylyltransferase0.0083 long-chain-fatty-acid--CoA ligase0.0773 transcriptional regulator0.1713 hypothetical protein0.0625 conserved hypothetical protein0.1197 30S ribosomal protein S150.1565 GTP-binding elongation factor family protein TypA/BipA0.0023 chromate transport protein0.1379 chromate transport protein0.1773 phosphoenolpyruvate carboxykinase (ATP)0.1236 uracil phosphoribosyltransferase0.0007 AraC/XylS family transcriptional regulator0.2943 putative MFS transporter0.2750 putative multidrug resistance protein0.0566 outer membrane efflux protein precursor0.2373 conserved hypothetical protein0.0350 adenosylhomocysteinase

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0.0010 carboxy-terminal processing protease precursor0.0179 putative PfkB family carbohydrate kinase0.0348 putative amidophosphoribosyl-transferase0.0392 inositol-1-monophosphatase0.0797 conserved hypothetical protein0.1864 ribokinase0.0408 ribokinase0.0031 SusC homolog0.1586 SusD homolog0.1947 Glycoside hydrolase, family 350.2234 putative inosine-uridine preferring nucleoside hydrolase0.2466 putative integral membrane protein0.0650 Metallophosphoesterase0.0002 alkyl hydroperoxide reductase subunit F0.1995 alkyl hydroperoxide reductase C22 protein0.0376 sodium-dependent multivitamin transporter0.2830 dihydrodipicolinate synthase0.0266 putative mutT family protein0.0917 TPR domain-containing protein0.0112 putative TonB-dependent receptor0.0161 SusC homolog0.3064 SusD homolog0.1966 SusC homolog0.0040 SusD homolog0.1638 conserved hypothetical protein0.0238 conserved hypothetical protein0.0649 beta-glucanase precursor0.0246 chitinase0.3119 two-component system sensor histidine kinase/response regulator, hybrid (one component system)0.1299 DNA topoisomerase I0.1499 putative lipoprotein0.0903 arginyl-tRNA synthetase0.1696 DNA-binding protein HU-beta0.2419 rhomboid family protein0.0012 rhomboid family protein0.1351 endonuclease/exonuclease/phosphatase-like protein0.0177 peptidyl-dipeptidase0.1916 protein-export membrane protein SecD/SecF0.1199 2-oxoglutarate synthase subunit korA0.1826 2-oxoglutarate synthase subunit korB0.0687 putative lipoprotein releasing system transmembrane permease0.0797 ribosome-binding factor A

N/D O-methyltransferase0.1499 pyruvate kinase

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N/D 3-dehydroquinate dehydratase0.0046 integrase0.0000 TPR domain protein0.2296 possible thiol-disulfide oxidoreductase0.3053 magnesium chelatase, subunit ChlI0.0095 conserved hypothetical protein0.0108 putative lipoprotein0.0000 aldose 1-epimerase precursor0.0753 putative two-component system sensor histidine kinase0.0903 alpha-galactosidase (melibiase)0.2287 putative beta-xylosidase0.0781 hypothetical protein0.0000 periplasmic beta-glucosidase precursor0.0642 beta-mannosidase precursor0.0036 conserved hypothetical protein0.0357 Galactose-binding like protein0.0754 SusD homolog0.2148 SusC homolog0.0066 two-component system sensor histidine kinase/response regulator, hybrid (one component system)0.0841 putative outer membrane protein0.2795 tyrosine-protein kinase ptk0.1314 putative polysaccharide export protein0.1721 putative glycosyltransferase (family 4) involved in lipopolysaccharide biosynthesis0.0017 glycoside transferase family 40.2425 glycoside transferase family 40.1808 TonB box, N-terminal0.3152 glycoside transferase family 20.0603 putative succinyltransferase involved in succinoglycan biosynthesis0.1803 glycoside transferase family 140.3181 glycoside transferase family 140.0000 putative capsular polysaccharide synthesis protein0.2376 putative stress protein0.0000 putative colanic acid biosynthesis glycosyltransferase0.0760 serine O-acetyltransferase0.0584 glycoside transferase family 20.2672 putative acetyltransferase0.0890 lipopolysaccharide biosynthesis protein0.3102 CDP-glycerol glycerophosphotransferase0.1039 putative nucleotide-sugar dehydratase0.0023 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase0.1529 glycoside transferase family 20.0719 phosphoribosylglycinamide formyltransferase0.0364 WbqC-like protein family0.1268 nucleotide sugar transaminase

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0.0648 putative transcriptional regulator0.2595 putative UDP-galactose 4-epimerase0.0006 glycosyltransferase0.1779 AraC family transcriptional regulator0.0797 transposase0.1981 hypothetical protein0.0000 glycoside hydrolase family 930.0651 SusD homolog0.0084 SusC homolog0.1151 endo-1,4-beta-xylanase0.0011 NHL repeat protein0.1493 two-component system sensor histidine kinase/response regulator, hybrid (one-component system)0.0280 endo-1,4-beta-xylanase D precursor0.0446 hypothetical protein0.0187 arabinan endo-1,5-alpha-L-arabinosidase A precursor0.0657 putative glycoside hydrolase0.0509 hypothetical protein0.0000 Galactose-binding like protein0.0000 SusD homolog0.0969 SusC homolog0.0578 conserved hypothetical protein0.0757 glycosyltransferase-like protein0.1188 conserved hypothetical protein0.0042 putative L-arabinose isomerase0.1770 transcriptional regulator0.0038 putative Acetyl-CoA carboxylase, biotin carboxylase0.2990 putative glycosyslhydrolase0.0109 unsaturated glucuronylhydrolase0.2936 iduronate 2-sulfatase precursor0.1151 putative secreted protein0.0970 conserved hypothetical protein0.0059 conserved hypothetical protein0.0020 hypothetical protein0.2283 SusD homolog0.3098 SusC homolog0.1019 glycosyl hydrolase, family 880.1920 beta-galactosidase0.0407 two-component system sensor histidine kinase/response regulator, hybrid (one-component system)0.0496 acetyl-CoA synthetase0.0602 hypothetical protein0.0092 hypothetical protein0.0982 conserved hypothetical protein, putative cell wall-associated protein precursor0.0608 hypothetical protein0.0290 putative non-specific DNA-binding protein

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0.0670 conserved hypothetical protein0.0699 hypothetical protein0.0000 transcriptional regulator0.2631 Methionyl-tRNA synthetase0.0000 putative transmembrane transport protein, putative lipopolysaccharide biosynthesis protein0.0765 hypothetical protein0.2212 glycoside transferase family 40.1695 putative glycosyltransferase0.0069 glycoside transferase family 40.0780 putative transcriptional regulator0.2484 multidrug resistance protein0.0241 multidrug resistance protein mexB (multidrug-efflux protein)0.0250 putative multidrug resistance protein0.0208 putative hexapeptide transferase family protein0.2280 putative UDP-N-acetylglucosamine 2-epimerase0.2826 UDP-N-acetyl-D-mannosamine dehydrogenase0.0000 glycoside transferase family 40.0000 glycoside transferase family 20.2834 putative alpha-1,2-mannosidase0.3112 putative alpha-1,6-mannanase0.1774 Concanavalin A-like lectin/glucanase0.0303 SusD homolog0.2522 SusC homolog0.1537 L-rhamnose-proton symporter0.0001 conserved hypothetical protein0.0194 formate acetyltransferase 20.2870 putative pyruvate formate-lyase 3 activating enzyme0.2157 transcriptional regulator0.2887 conserved hypothetical protein0.0035 glycosyl hydrolase family 43 protein0.0002 hypothetical protein0.0118 putative lipase0.2539 hypothetical protein0.0005 glycosyl hydrolase, family 880.0053 chondroitinase AC precursor0.0010 conserved hypothetical protein0.0892 Galactose-binding like protein0.3131 SusD homolog0.0441 SusC homolog0.0671 beta-galactosidase0.1474 alpha-L-fucosidase precursor0.0055 two-component system sensor histidine kinase/response regulator, hybrid (one-component system)0.2130 putative methyltransferase0.0780 transcriptional regulator

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0.0760 hypothetical protein0.0603 putative nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase0.0000 FKBP-type peptidyl-prolyl cis-trans isomerase, outer membrane protein precursor0.0002 peptidylprolyl isomerase0.0000 transcriptional regulator0.0052 conserved hypothetical protein, putative membrane protein0.1658 transposase0.1534 hypothetical protein0.1820 conserved hypothetical protein0.1593 conserved hypothetical protein0.0054 conserved hypothetical protein0.1448 DNA repair protein0.0704 integrase0.0557 hypothetical protein0.0008 hypothetical protein0.1171 hypothetical protein0.2191 putative integrase0.0467 hypothetical protein0.1006 virulence-associated protein E-like protein0.0000 hypothetical protein0.0760 conserved hypothetical protein0.0464 conserved hypothetical protein with relaxase/mobilization nuclease domain

N/D hypothetical protein0.0221 hypothetical protein0.0514 conserved hypothetical protein0.0023 helicase IV0.1917 conserved hypothetical protein0.0470 ATP-dependent DNA helicase0.2707 putative transcriptional regulator0.0354 Toll-Interleukin receptor0.0088 SWIM Zn-finger domain protein0.1230 conserved hypothetical protein0.0075 Regulator of chromosome condensation, RCC10.0819 D-alanyl-D-alanine dipeptidase0.2829 conserved hypothetical protein0.0350 beta-glucosidase (gentiobiase)0.0028 RNA polymerase ECF-type sigma factor0.2080 putative anti-sigma factor0.1557 SusC homolog0.3007 SusD homolog0.1529 putative chitobiase0.0000 conserved hypothetical protein0.1484 TonB-dependent receptor0.0306 acid phosphatase

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0.0329 putative mechano-sensitive ion channel0.0017 putative Na+/Ca2+ exchanger protein, cation antiporter0.0179 conserved hypothetical protein0.0385 conserved hypothetical protein0.2817 hypothetical protein0.0004 conserved hypothetical protein0.1950 SusC homolog0.1284 SusD homolog0.0058 glycosylhydrolase, putative xylanase0.0000 conserved hypothetical protein0.2048 putative glycosylase0.0530 Na+/glucose symporter0.0018 putative exported phosphoesterase protein0.0439 conserved hypothetical protein0.0000 conserved hypothetical protein, with a weak acyltransferase domain0.1429 DNA topoisomerase IV subunit B0.0705 phosphopantetheine adenylyltransferase0.0006 carboxy-terminal processing protease precursor0.2842 SusC homolog0.2522 RNA polymerase ECF-type sigma factor0.0002 putative anti-sigma factor0.1779 hypothetical protein0.0191 putative DNA-binding protein0.2722 Histone-like bacterial DNA-binding protein0.1351 conserved hypothetical protein0.1288 putative xylanase0.0530 hypothetical protein0.0670 SusD homolog0.2668 SusC homolog0.2697 NHL repeat containing protein0.1435 hypothetical protein0.0190 two-component system sensor histidine kinase/response regulator, hybrid (one-component system)0.0671 chitinase precursor0.0467 mucin-desulfating sulfatase0.1346 transcriptional regulator0.3184 putative cytochrome B subunit0.0226 succinate dehydrogenase flavoprotein subunit0.0544 succinate dehydrogenase iron-sulfur protein0.1700 putative lipoprotein0.0347 N-acetylgalactosamine-6-sulfatase precursor0.0676 transcriptional regulator0.0756 Quinonprotein alcohol dehydrogenase0.1940 hypothetical protein0.0488 putative transmembrane protein

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0.1141 hypothetical protein0.2676 hypothetical protein0.2682 hypothetical protein0.1946 alpha-galactosidase precursor0.2280 conserved hypothetical protein0.0203 Quinoprotein amine dehydrogenase

N/D transposase, invertase0.2905 putative disulphide-isomerase0.1770 Smf protein DNA processing chain A0.0084 thioesterase family-like protein0.0004 collagenase precursor0.0294 putative TIM-barrel enzyme, possible dehydrogenase, contains a highly conserved dihydrouridine synthase domain0.3176 Phosphoesterase, PA-phosphatase0.1785 NAD-dependent epimerase/dehydratase family protein0.0642 hypothetical protein0.2284 ribonuclease R0.1138 5-nitroimidazole antibiotic resistance protein0.1349 conserved hypothetical protein0.3158 cysteine synthase A0.1002 putative pectin degradation protein0.0523 2,6-beta-D-fructofuranosidase precursor0.3126 putative ATPase0.1425 lipase, putative0.1993 alpha-xylosidase0.0011 alpha-glucosidase II0.2948 cycloisomaltooligosaccharide glucanotransferase0.0366 conserved hypothetical protein0.2007 SusD homolog0.1219 SusC homolog0.0000 putative regulatory protein0.0250 beta-galactosidase0.3095 arylsulfatase (aryl-sulfate sulphohydrolase)0.2149 putative secreted xylosidase0.1275 putative sulfatase0.1574 alpha-L-arabinofuranosidase A precursor0.2836 two-component system sensor histidine kinase/response regulator, hybrid (one-component system)0.2080 hypothetical protein

N/D hypothetical protein0.0888 lipase, putative esterase0.2477 N-sulphoglucosamine sulphohydrolase precursor0.0000 SusD homolog0.3166 SusC homolog0.0559 hypothetical protein0.0038 conserved hypothetical protein

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0.0000 arylsulfatase (aryl-sulfate sulphohydrolase)0.0546 arylsulfatase (aryl-sulfate sulphohydrolase)0.0006 putative beta-xylosidase0.0000 arylsulfatase A precursor0.0295 conserved hypothetical protein0.0052 hypothetical protein0.0069 putative lipoprotein0.0730 putative transmembrane efflux protein0.0354 beta-galactosidase0.0128 putative proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydraogenase0.0132 GTP-binding protein0.0758 putative oxidoreductase0.1140 prolipoprotein diacylglyceryl transferase0.2672 chloramphenicol acetyltransferase0.2914 conserved hypothetical protein0.0158 DNA mismatch repair protein mutS0.1639 transcriptional regulator0.1949 conserved hypothetical protein0.0116 putative sialic acid-specific acetylesterase0.0760 hypothetical protein0.2258 leucyl-tRNA synthetase0.1067 putative transmembrane protein0.1812 putative xanthosine triphosphate pyrophosphatase0.0017 putative flagellar motor protein MotB0.1245 Alpha-1,2-mannosidase, putative0.1319 alpha-galactosidase (melibiase)0.2308 sialic acid-specific 9-O-acetylesterase0.1468 alpha-galactosidase0.0466 two-component system sensor histidine kinase/response regulator, hybrid (one-component system)0.0321 integrase0.0968 integrase0.0590 conserved hypothetical protein0.1252 hypothetical protein

N/D Putative DNA binding protein0.0176 Putative DNA binding protein0.0586 conserved hypothetical protein0.0754 mobilization protein BmgB0.0396 mobilization protein BmgA0.0621 conserved hypothetical protein0.1056 hypothetical protein0.0000 TenA family transcriptional activator-like protein0.1113 hypothetical protein0.0423 hypothetical protein0.1054 hypothetical protein

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0.0139 transcriptional regulator0.0510 hypothetical protein0.0525 ATP-dependent DNA helicase0.1188 putative DNA-binding protein0.0019 two-component system sensor histidine kinase/response regulator0.2809 glycoside hydrolase family 950.0575 SusC homolog0.0001 SusD homolog0.0000 Galactose-binding-like protein0.0000 conserved hypothetical protein0.0001 hypothetical protein0.0212 hypothetical protein0.0721 glycerophosphoryl diester phosphodiesterase0.1259 alpha-glucosidase, putative0.0196 quinolinate synthetase A0.0408 tRNA/rRNA methyltransferase0.0052 conserved hypothetical protein0.1785 conserved hypothetical protein0.0224 putative Fe-S oxidoreductase0.3154 alpha-xylosidase0.2165 hypothetical protein0.0925 sialic acid-specific 9-O-acetylesterase0.1554 two-component system sensor histidine kinase/response regulator, hybrid (one-component system)0.2672 glycoside hydrolase family 950.1138 SusC homolog0.0593 SusD homolog0.0390 Aldehyde dehydrogenase0.1682 mucin-desulfating sulfatase0.2435 beta-hexosaminidase precursor0.0151 beta-galactosidase0.0226 putative transmembrane protein0.0019 putative sulfate transporter, permease0.2915 rubrerythrin0.1267 hypothetical protein0.1296 L-aspartate oxidase0.1900 conserved hypothetical protein0.2791 dihydrolipoamide dehydrogenase0.0000 penicillin-binding protein, D-alanyl-D-alanine carboxypeptidase0.1307 conserved hypothetical protein0.2923 hypothetical protein0.1466 putative RNA polymerase ECF-type sigma factor0.0000 hypothetical protein0.1976 TonB0.0000 putative coenzyme A transferase

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0.0634 hypothetical protein0.1744 conserved hypothetical protein

N/D putative transcriptional regulatorN/D hypothetical protein

0.0885 conserved hypothetical proteinN/D putative non-specific DNA-binding protein

0.0000 putative N-acetylmuramoyl-L-alanine amidase0.2041 hypothetical protein containing YD repeat0.0178 cell well associated RhsD protein precursor0.2401 hypothetical protein

N/D putative cell wall-associated protein precursor0.0001 conserved hypothetical protein, putative cell wall associated RhsD protein0.2455 hypothetical protein0.1470 conserved hypothetical protein, putative cell wall associated RhsD protein0.0758 Peptidyl-prolyl cis-trans isomerase0.0715 SAM dependent methyltransferase-like protein0.0608 cell division protein FtsX0.0754 conserved hypothetical protein0.1118 putative bacitracin resistance protein0.2588 tRNA pseudouridine synthase B0.3100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase0.0797 conserved hypothetical protein0.1746 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine0.0026 conserved hypothetical protein0.1086 hypothetical protein0.0770 S-adenosylmethionine synthetase0.0674 TPR-repeat-containing protein0.0001 hypothetical protein0.2796 hypothetical protein0.0919 hypothetical protein0.0185 putative lysine decarboxylase0.0763 conserved hypothetical protein0.0781 uroporphyrinogen-III synthase HemD, putative

N/D putative ribonuclease P protein component0.3176 conserved hypothetical protein0.0586 TatD-related DNase0.1773 tyrosyl-tRNA synthetase0.0680 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase0.1067 gluconate 5-dehydrogenase0.1803 Galactose mutarotase-like protein0.0268 conserved hypothetical protein0.3097 conserved hypothetical protein0.1171 conserved hypothetical protein0.1236 hypothetical protein

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0.1048 SusD homolog0.0209 SusC homolog0.0005 SusC homolog0.0007 SusD homolog0.0011 hypothetical protein0.0036 conserved hypothetical protein0.0124 hypothetical protein0.2759 putative iron-sulfur cluster-binding protein0.2067 polysaccharide deacetylase0.0000 conserved hypothetical protein0.0280 putative metal ABC transporter, ATP-binding protein0.3019 putative zinc ABC transporter, zinc-binding protein0.1940 conserved hypothetical protein0.1941 conserved hypothetical protein, putative integral membrane protein0.0000 putative transmembrane protein0.0000 phosphoribosylamine--glycine ligase0.0000 dipeptidyl peptidase IV0.0000 putative N6-adenine-specific DNA methylase0.0000 serine acetyltransferase0.2067 putative two-component system sensor histidine kinase0.2080 two-component system response regulator0.2109 hypothetical protein0.0000 DNA polymerase I0.2445 octaprenyl-diphosphate synthase0.0513 conserved hypothetical protein0.1119 putative deoxyribose-phosphate aldolase0.2838 putative pyrophosphatase0.2803 putative D-tyrosyl-tRNA deacylase0.1166 excinuclease ABC subunit C0.0618 adenine phosphoribosyltransferase0.0000 glucose-inhibited division protein A0.0023 RNA polymerase ECF-type sigma factor0.0231 putative anti-sigma factor0.0378 SusC homolog0.0084 SusD homolog0.0943 hypothetical protein0.1198 hypothetical protein0.2970 conserved hypothetical protein0.2882 conserved hypothetical protein0.0468 RNA polymerase ECF-type sigma factor0.2473 putative anti-sigma factor0.0351 SusC homolog0.0072 SusD homolog0.0085 hypothetical protein

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0.1404 conserved hypothetical protein0.1803 conserved hypothetical protein with conserved domain0.0719 putative spore maturation protein A/B0.0593 Holliday junction DNA helicase ruvB0.1820 Phospholipase/Carboxylesterase0.1102 polysaccharide biosynthesis protein0.0003 putative integral membrane protein0.0004 conserved hypothetical protein0.0461 putative integral membrane protein0.0801 peptidase0.1959 beta-glucuronidase0.1765 beta-galactosidase0.0778 putative alpha-glucosidase0.0833 hypothetical protein0.0886 SusD homolog0.0003 SusC homolog0.0296 conserved hypothetical protein, with a conserved domain0.0092 alpha-glucosidase II0.1961 beta-glucosidase0.2980 putative alpha-1,6-mannanase0.2911 two-component system sensor histidine kinase/response regulator, hybrid (one-component system)0.1339 ATP-dependent RNA helicase0.0108 possible protein-tyrosine-phosphatase0.0293 fructokinase0.1940 putative sugar isomerase0.1979 lysine decarboxylase0.0205 putative zinc protease ymxG0.2067 transcriptional regulator0.0917 SusC homolog0.2685 SusD homolog0.2192 glucosylceramidase precursor0.0028 hypothetical protein0.0346 thermostable beta-glucosidase B0.0191 hypothetical protein0.2836 hypothetical protein0.2191 conserved hypothetical protein0.1551 signal peptidase I0.0372 signal peptidase I0.0760 dihydrodipicolinate reductase0.0946 conserved hypothetical protein0.0668 putative thioredoxin family protein0.0481 conserved hypothetical protein0.0529 chondroitinase (chondroitin lyase) precursor0.0923 conserved hypothetical protein

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0.0069 putative nifR3 family TIM-barrel enzyme with dihydrouridine synthase domain0.0797 ATP-dependent DNA helicase recG0.0023 conserved hypothetical protein0.2894 hypothetical protein0.3097 hypothetical protein0.0792 SusD homolog0.2870 SusC homolog0.2855 arylsulfatase A precursor (ASA)0.0046 two-component system sensor histidine kinase/response regulator, hybrid (one-component system)0.0499 conserved hypothetical protein0.0680 UDP-N-acetylglucosamine acetyltransferase0.0000 outer membrane protein oprM precursor, multidrug resistance protein0.2502 AcrB/AcrD family multidrug resistance protein0.2212 AcrA/AcrE family multidrug resistance protein0.0323 beta-galactosidase0.0000 conserved hypothetical protein0.1811 conserved hypothetical protein0.1359 putative phenylacetic acid degradation protein0.0331 hypothetical protein0.1466 SusD homolog0.2451 SusC homolog0.0941 Quinoprotein amine dehydrogenase0.0464 putative unsaturated glucuronyl hydrolase0.1517 putative sulfatase yidJ0.0134 putative chondroitinase (chondroitin lyase)0.2129 cysteinyl-tRNA synthetase0.0297 haloacid dehalogenase-like hydrolase0.2068 Snf2 family helicase0.1126 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase0.0000 putative auxin-regulated protein0.0361 6-phosphofructokinase0.0909 ribonuclease III0.1707 3-oxoacyl-[acyl-carrier-protein] synthase II

N/D acyl carrier protein0.0448 phosphoribosylglycinamide formyltransferase0.2917 erythronate-4-phosphate dehydrogenase0.0019 heptosyltransferase0.0000 lipopolysaccharide core biosynthesis protein LpsA0.0000 Tyrosine protein kinase, active site0.0000 glycoside transferase family 20.0000 glycoside transferase family 20.0000 glycoside transferase family 40.0000 glycoside transferase family 40.0000 glycoside transferase family 4

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0.0000 glycoside transferase family 20.0000 glycoside transferase family 20.0002 glycoside transferase family 20.0196 spermidine n1-acetyltransferase0.0137 putative carbamoyl-phosphate-synthetase0.0048 aspartate aminotransferase0.0037 nucleotide sugar transaminase0.0065 glycoside transferase family 140.0172 GtrA-like protein0.1071 glycoside transferase family 20.0454 putative membrane protein0.0496 conserved hypothetical protein0.0065 conserved hypothetical protein0.0053 Homeodomain-like protein0.0378 Histone-like bacterial DNA-binding protein0.0256 putative helicase0.0366 ABC transporter, ATP-binding protein0.0000 putative polysaccharide deacetylase0.0002 glycoside transferase family 20.0001 conserved hypothetical protein0.0084 GtrA-like protein0.0685 ribonuclease H-related protein0.0346 nitroreductase0.0000 shikimate kinase0.0000 putative arginine decarboxylase0.0000 putative acetylglutamate kinase0.0025 RNA polymerase ECF-type sigma factor0.0020 conserved hypothetical protein

N/D putative lipoprotein0.2133 putative zinc protease0.2481 putative transmembrane protein0.0023 Toll-Interleukin receptor0.1408 conserved hypothetical protein0.2661 putative nitrogen utilization substance protein0.1966 translation initiation factor IF-20.2796 Colicin V production protein0.1190 ABC transporter permease0.0781 ABC transporter ATP-binding protein0.1553 conserved hypothetical protein, putative ABC transporter permease component0.2398 aminotransferase, putative cysteine desulfurase0.0285 conserved hypothetical protein0.2602 pyrophosphate-energized vacuolar membrane proton pump0.0072 ribonuclease HII0.0213 conserved hypothetical protein

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0.0086 Mg2+/Co2+ transporterN/D hypothetical proteinN/D putative receptor protein

0.0269 hypothetical protein0.2513 putative thiol:disulfide interchange protein0.0004 2,3-bisphosphoglycerate-independent phosphoglycerate mutase0.0031 conserved hypothetical protein0.1241 hypothetical protein0.0414 hypothetical protein0.0025 hypothetical protein0.0007 hypothetical protein0.0000 conserved hypothetical protein

N/D hypothetical protein0.0383 conserved hypothetical protein0.0067 hypothetical protein0.1113 DNA gyrase subunit B0.0005 ribosomal protein S200.0000 DNA repair protein0.0644 conserved hypothetical protein0.2370 hypothetical protein0.0064 conserved hypothetical protein0.0465 hypothetical protein0.0132 hypothetical protein0.2969 hypothetical protein0.0507 hypothetical protein0.3189 conserved hypothetical protein0.0628 hypothetical protein0.0760 hypothetical protein0.0000 conserved hypothetical protein0.0603 YqeY-like protein0.1477 cell division protein FtsZ0.1638 cell division protein FtsA0.0780 cell division protein FtsQ0.0450 UDP-N-acetylmuramate--alanine ligase0.1376 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase0.0326 rod shape-determining protein rodA

N/D UDP-N-acetylmuramoylalanine--D-glutamate ligase0.0781 phospho-N-acetylmuramoyl-pentapeptide-transferase0.0859 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase0.0233 penicillin-binding protein0.0602 conserved hypothetical protein0.0414 S-adenosyl-methyltransferase mraW0.0649 putative cell division protein0.2234 RNA polymerase ECF-type sigma factor

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0.0001 Phospholipid/glycerol acyltransferase0.0000 hemolysin A0.2191 dGTP triphosphohydrolase0.1344 deoxyuridine 5'-triphosphate nucleotidohydrolase0.3068 TPR domain protein0.2502 conserved hypothetical protein0.0760 putative peptidase0.0001 two-component system sensor histidine kinase/response regulator, hybrid (one-component system)0.2043 hypothetical protein0.1697 putatuve glycosylhydrolase0.0495 ApbE-like lipoprotein0.0239 probable secreted glycosyl hydrolase0.1135 putative dehydrogenase0.2273 hypothetical protein0.0004 putative hydrogenase0.1423 hypothetical protein0.0000 SusD homolog0.2161 SusC homolog0.1247 conserved hypothetical protein0.1020 glutaminase A0.0276 integrase

N/D integraseN/D conserved hypothetical protein

0.1940 putative glutaminase A0.2938 conserved hypothetical protein containing NHL repeat0.1704 SusC homolog0.0684 SusD homolog0.3059 hypothetical protein0.2300 N-acetylgalactosamine-6-sulfatase precursor0.0833 arylsulfatase (aryl-sulfate sulphohydrolase)0.0009 arylsulfatase (aryl-sulfate sulphohydrolase)0.0386 arylsulfatase B precursor0.1132 putative ATPase0.1699 glutaminase A0.0041 conserved hypothetical protein, with a conserved domain0.0680 putative outer membrane protein, probably involved in nutrient binding0.0940 SusC homolog0.0128 SusD homolog0.0498 hypothetical protein0.0000 Peptidase aspartic, active site0.3118 conserved hypothetical protein0.1477 conserved hypothetical protein0.0464 hypothetical protein0.0966 putative alpha-1,6-mannanase

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0.2423 hypothetical proteinN/D glutaminase A

0.1555 hypothetical protein0.1638 SusC homolog0.0716 SusD homolog0.1478 hypothetical protein0.2049 conserved hypothetical protein0.0003 conserved hypothetical protein

N/D hypothetical protein0.0011 hypothetical protein0.0000 glutaminase A0.0290 beta-galactosidase0.0793 conserved hypothetical protein0.0765 putatuve glycosylhydrolase0.0774 arabinan endo-1,5-alpha-L-arabinosidase A precursor0.2676 RNA polymerase ECF-type sigma factor0.3134 putative anti-sigma factor0.0090 SusC homolog0.0000 SusD homolog0.1514 alpha-1,6-mannanase0.1928 Concanavalin A-like lectin/glucanase0.2940 Concanavalin A-like lectin/glucanase0.1837 alpha-1,6-mannanase0.1054 conserved hypothetical protein0.0139 glutaminase0.0718 alpha-1,2-mannosidase0.0000 conserved hypothetical protein0.0681 aldose 1-epimerase precursor0.2220 putative alpha-1,2-mannosidase0.1827 conserved hypothetical protein0.2495 aldose 1-epimerase precursor0.0765 O-antigen polymerase0.1602 hypothetical protein0.0520 hypothetical protein0.3147 conserved hypothetical protein0.0200 hypothetical protein0.0337 hypothetical protein0.2227 hypothetical protein0.0000 hypothetical protein0.0605 conserved hypothetical protein0.0056 hypothetical protein0.0460 hypothetical protein0.3140 hypothetical protein0.1262 O-antigen polymerase

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0.0275 glutaminase0.1522 hypothetical protein0.0008 ATPase0.0000 acetylornithine deacetylase0.0045 putative long-chain-fatty-acid--CoA ligase0.0013 putative zinc protease0.2429 peptide chain release factor RF-20.1860 Phosphate-selective porin O and P0.0305 adenylate cyclase-like protein0.0080 putative membrane protein0.0006 transcriptional regulator0.0004 putative transposase0.1772 putative endonuclease0.0581 endonuclease/exonuclease/phosphatase family0.2676 TonB-dependent receptor0.1426 conserved hypothetical protein0.3023 conserved hypothetical protein0.0344 putative endonuclease precursor

N/D Putative DNA binding0.0801 putative TonB-dependent receptor0.0004 conserved hypothetical protein0.1974 periplasmic beta-glucosidase precursor0.0324 SusD homolog0.2672 SusC homolog0.2205 TPR-repeat-containing protein0.0770 hypothetical protein0.1809 hypothetical protein0.0205 hypothetical protein0.2087 hypothetical protein0.0000 hypothetical protein0.1345 putative ribokinase0.0203 putative protease0.1419 conserved hypothetical protein0.0301 topoisomerase IV subunit A0.2473 putative dehydrogenase0.1940 hypothetical protein0.0516 putative dehydrogenase0.0797 thiamine biosynthesis lipoprotein ApbE0.3189 putative oxidoreductase0.0073 putative dehydrogenase0.0770 glucosamine-6-phosphate isomerase0.0056 N-acetylglucosamine-6-phosphate deacetylase0.0240 glucose/galactose transporter0.0001 alpha-N-acetylglucosaminidase precursor

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0.0344 hypothetical protein0.1041 alpha-galactosidase precursor0.2149 putative hydrolase lipoprotein0.2469 conserved hypothetical protein with fibronectin, type III-like fold0.0770 hypothetical protein0.2546 hypothetical protein0.0003 sialic acid-specific 9-O-acetylesterase0.0140 beta-hexosaminidase precursor0.1613 beta-mannosidase precursor0.1428 ROK family transcriptional repressor0.1459 glucosamine--fructose-6-phosphate aminotransferase0.1959 hypothetical protein0.2470 SusD homolog0.0000 SusC homolog0.0258 N-acylglucosamine 2-epimerase0.2500 sugar-proton symporter0.0942 hypothetical protein0.0022 probable sialidase0.2707 transcriptional regulator0.1428 Histone-like bacterial DNA-binding protein0.2121 glycyl-tRNA synthetase0.1239 putative FKBP-type peptidyl-prolyl cis-trans isomerase fkpA0.1869 LacI family transcriptional regulator0.0186 putative oxidoreductase0.0841 conserved hypothetical protein0.0256 fucose permease0.0408 sorbitol dehydrogenase0.1558 conserved hypothetical protein0.2205 putative transmembrane protein0.0024 AmpG protein, beta-lactamase induction signal transducer0.3097 amidase enhancer precursor0.0107 glycoside transferase family 20.1972 sodium/iodide co-transporter0.1205 conserved hypothetical protein0.0558 conserved hypothetical protein0.0048 conserved hypothetical protein0.0781 ABC transporter, ATP-binding protein0.0288 conserved hypothetical protein0.1940 hypothetical protein0.0004 putative lipoprotein0.1297 hypothetical protein0.1537 SusD homolog0.1937 SusC homolog

N/D transposase

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N/D hypothetical protein0.0780 aspartate-semialdehyde dehydrogenase0.1094 conserved hypothetical protein0.2607 Na+/H+ anti-porter0.0456 ThiF family protein, putative dinucleotide-utilizing enzyme involved in molybdopterin and thiamine biosynthesis0.0770 lipoprotein releasing system ATP-binding protein

N/D conserved hypothetical protein0.1352 Na+-dependent transporter0.0040 putative transmembrane protein0.0781 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase0.0021 two-component system sensor histidine kinase0.0780 dihydropteroate synthase0.2566 putative transmembrane protein0.1484 putative modulator of DNA gyrase0.0760 putative modulator of DNA gyrase0.0586 putative lemA protein0.0649 conserved hypothetical protein0.2260 conserved hypothetical protein

N/D hypothetical protein0.0010 beta-galactosidase precursor0.0384 arabinosidase0.0020 putative beta-xylosidase0.0754 alpha-L-arabinofuranosidase A precursor0.2676 hypothetical protein0.2109 alpha-xylosidase0.0597 transcriptional regulator0.0502 alpha-glucosidase0.2970 putative endo-1,4-beta-xylanase0.2622 putative beta-xylosidase0.1199 putative alpha-glucosidase0.0007 alpha-L-fucosidase precursor0.0555 conserved hypothetical protein0.0000 transcriptional regulator0.0479 conserved hypothetical protein0.0780 conserved hypothetical protein0.2167 SusC homolog0.2569 SusD homolog0.0044 hypothetical protein0.1766 TonB0.3142 Six-hairpin glycosidase0.1981 endo-1,4-beta-xylanase D precursor0.2595 conserved hypothetical protein0.2659 conserved hypothetical protein0.0472 two-component system sensor histidine kinase/response regulator, hybrid (one-component system)

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0.2248 conserved hypothetical protein, with a conserved domain0.2137 SusC homolog0.0005 SusD homolog0.1794 hypothetical protein0.2229 beta-glucanase precursor0.0765 hypothetical protein0.1015 beta-glucanase precursor0.0003 Neuraminidase0.1750 glycosyl hydrolase, family 880.1682 putative acetyltransferase0.1252 conserved hypothetical protein0.0461 putative membrane protein0.1946 conserved hypothetical protein, putative membrane protein0.0589 phosphate acetyltransferase0.0094 acetate kinase0.0833 glycoside transferase family 20.1042 putative DNA repair protein0.0670 conserved hypothetical protein0.0630 UDP-2,3-diacylglucosamine hydrolase0.0176 alpha-amylase, susG0.0000 outer membrane protein SusF0.0031 outer membrane protein SusE0.0120 SusD0.2879 SusC0.0750 alpha-glucosidase SusB0.0150 alpha-amylase (neopullulanase) SusA0.0006 regulatory protein SusR

N/D transposaseN/D conserved hypothetical protein

0.0370 alkaline phosphatase III precursor0.0000 elongation factor P0.0687 50S ribosomal protein L340.0797 conserved hypothetical protein0.0557 ribosomal large subunit pseudouridine synthase D

N/D D-alanine--D-alanine ligase0.0975 Phospholipid/glycerol acyltransferase0.1364 conserved hypothetical protein0.1161 Rhodanese-like protein0.0000 ornithine carbamoyltransferase0.0000 gamma-glutamyl phosphate reductase0.2524 glutamate 5-kinase0.0904 putative aspartate aminotransferase0.0293 conserved hypothetical protein0.0541 glutamate racemase

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0.0405 putative outer membrane protein OmpH0.0000 cationic outer membrane protein precursor0.1898 putative outer membrane protein0.0561 undecaprenyl pyrophosphate synthetase0.3073 conserved hypothetical protein0.0598 riboflavin biosynthesis protein ribD0.0000 putative protoporphyrinogen oxidase0.2514 putative regulatory protein0.0000 orotate phosphoribosyltransferase0.0000 conserved hypothetical protein0.0000 argininosuccinate lyase0.0602 oxidoreductase0.2203 hypothetical protein0.0000 conserved hypothetical protein0.1277 conserved hypothetical protein0.0008 two-component system sensor histidine kinase/response regulator, hybrid (one-component system)0.0357 Na+/dicarboxylate or sulfate symporter0.0336 hypothetical protein0.2479 hypothetical protein0.0232 conserved hypothetical protein0.2020 conserved hypothetical protein0.2540 conserved hypothetical protein0.1538 conserved hypothetical protein0.0000 hypothetical protein0.1803 conserved hypothetical protein0.2584 RNA polymerase ECF-type sigma factor0.0350 putative anti-sigma factor0.1885 SusC homolog0.0002 SusC homolog0.3140 SusD homolog0.1638 endo-beta-N-acetylglucosaminidase F2 precursor (mannosyl-glycoprotein endo-beta-N-acetyl-glucosaminidase F2)0.0547 Concanavalin A-like lectin/glucanase0.0765 acetyl-coenzyme A synthetase0.0074 transcriptional regulator0.0838 pyrroline-5-carboxylate reductase0.0000 acetylornithine aminotransferase0.0000 N-acetyl-gamma-glutamyl-phosphate reductase0.0000 argininosuccinate synthase0.0000 hypothetical protein0.0000 arginine repressor, transcriptional regulator of arginine metabolism0.0000 rhamnulose kinase/L-fuculose kinase0.0002 L-rhamnose isomerase0.0781 L-rhamnose/H+ symporter0.1833 rhamnulose-1-phosphate aldolase

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0.0169 lactaldehyde reductase0.1145 transcriptional regulator0.0770 conserved hypothetical protein0.0602 transcriptional regulator0.0541 3-oxoacyl-[acyl-carrier protein] reductase0.1749 ribosomal large subunit pseudouridine synthase D0.0388 Alpha-1,2-mannosidase, putative0.0052 alpha-mannosidase0.2836 glycoside transferase family 320.0665 glycoside transferase family 320.0592 hypothetical protein0.0514 conserved hypothetical protein0.0290 conserved hypothetical protein0.1529 putative glycosidase, PH117-related0.1803 conserved hypothetical protein0.0229 glycoside hydrolase family 730.0032 putative endonuclease/exonuclease/phosphatase family protein0.0600 putative alpha-1,2-mannosidase0.0760 hypothetical protein0.2389 two-component system sensor histidine kinase/response regulator, hybrid (one-component system)0.0798 conserved hypothetical protein with NHL repeat0.0520 SusC homolog0.0772 SusD homolog0.3128 hypothetical protein0.0000 Concanavalin A-like lectin/glucanase0.2465 putative alpha-1,6-mannanase0.0814 hypothetical protein0.0048 hypothetical protein

N/D transposaseN/D putative secreted sulfatase ydeN precursor

0.0598 possible alpha-galactosidase0.1380 putative exported fucosidase0.0116 putative sulfatase yidJ0.0280 two-component system sensor histidine kinase/response regulator, hybrid (one-component system)0.1689 rteB, two-component system response regulator0.1940 peptidyl-prolyl cis-trans isomerase, cyclophilin-type0.3038 putative zinc protease0.0040 putative transport protein, multidrug efflux protein0.0708 two-component system sensor histidine kinase0.0000 conserved hypothetical protein0.0000 putative outer membrane protein0.2502 nucleotidyltransferase family protein0.0025 ABC transporter ATP-binding protein0.0303 putative endothelin-converting enzyme

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0.1579 putative endothelin-converting enzyme0.0598 phosphoribosylaminoimidazole carboxy formyl formyltransferase; inosine-monophosphate cyclohydrolase; bifunctional purine biosynthesis protein purH0.0288 rod shape-determining protein MreB

N/D rod shape-determining protein0.0765 putative membrane protein0.3041 penicillin-binding protein 2 (PBP-2)0.0383 rod shape-determining protein rodA0.0832 conserved hypothetical protein0.0000 conserved hypothetical protein

N/D putative DNA polymerase III, delta subunit0.0493 5,10-methylenetetrahydrofolate reductase0.0548 conserved hypothetical protein0.0219 putative bacterioferritin-related protein0.0753 hypothetical protein

N/D transposaseN/D conserved hypothetical proteinN/D conserved hypothetical proteinN/D hypothetical proteinN/D conserved hypothetical proteinN/D methyltransferaseN/D hypothetical protein

0.0690 conserved hypothetical protein0.0580 50S ribosomal protein L32 (Ribosomal protein I)0.0304 3-oxoacyl-[acyl-carrier-protein] synthase III0.0370 putative GTP-binding protein0.0498 putative phosphoglycerate dehydrogenase0.0663 ABC transporter ATP-binding protein0.1262 putative ABC transporter0.0844 ABC transporter ATP-binding protein0.1779 putative RNA-binding protein rbpA0.2080 FKBP-type peptidyl-prolyl cis-transisomerase (trigger factor)0.0000 ATP-dependent Clp protease proteolytic subunit 20.2785 ATP-dependent Clp protease ATP-binding subunit0.0000 ATP-dependent DNA helicase recQ0.0000 inosine-5'-monophosphate dehydrogenase0.0036 peptidyl-prolyl cis-trans isomerase0.0547 conserved hypothetical protein0.1531 peptidyl-prolyl cis-trans isomerase0.1205 conserved hypothetical protein0.1940 conserved hypothetical protein0.0001 DNA mismatch repair protein mutL0.0086 major outer membrane protein OmpA0.2069 hypothetical protein0.0035 SusC homolog

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0.1826 SusD homolog0.0765 conserved hypothetical protein0.1425 Flavodoxin-like protein0.3140 alpha-1,2-mannosidase0.0000 conserved hypothetical protein0.1585 Concanavalin A-like lectin/glucanase0.0000 Concanavalin A-like lectin/glucanase0.0480 endo-alpha-mannosidase0.0017 conserved hypothetical protein0.1142 tryptophanyl-tRNA synthetase0.1235 hypothetical protein0.0960 glutamine-dependent carbamyl phosphate synthetase0.0676 hypothetical protein0.0617 beta-N-hexosaminidase, glycosyl hyrolase family 200.0452 conserved hypothetical protein0.0680 putative maltose O-acetyltransferase0.0006 adenylosuccinate lyase0.0676 ribosomal large subunit pseudouridine synthase B0.0634 asparaginyl-tRNA synthetase0.0651 hypothetical protein

N/D 50S ribosomal protein L130.1773 30S ribosomal protein S90.1972 30S ribosomal protein S2 (BS1)0.2333 elongation factor Ts (EF-Ts)0.0148 putative translation initiation factor SUI10.0320 Carboxypeptidase regulatory region0.1515 putative outer membrane protein0.0593 putative DNA binding protein0.2539 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase0.0742 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0.0925 putative phosphohydrolase, Icc family0.1982 conserved hypothetical protein

N/D hypothetical protein0.0522 putative tRNA (5-methylaminomethyl-2-thiouridylate) methyltransferase0.0663 subtilisin-like serine protease0.0252 putative exodeoxyribonuclease VII large subunit0.3008 Exonuclease VII, small subunit0.0000 branched-chain amino acid aminotransferase0.0254 conserved hypothetical protein0.0000 putative methyltransferase0.0000 Mrp/Nbp35 family ATP-binding protein0.0330 TonB0.0063 putative thiol:disulfide interchange protein DsbE0.0608 TonB

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0.2940 transcriptional regulator0.0676 hypothetical protein0.1078 hypothetical protein0.0258 putative transport-related membrane protein0.2435 transporter, putative0.0203 putative multidrug resistance protein0.0507 putative alkaline protease aprF0.0724 conserved hypothetical protein0.0946 N-6 Adenine-specific DNA methylase0.1884 conserved hypothetical protein with ATPase domain0.1621 conserved hypothetical protein0.0000 VWA containing CoxE family protein0.0000 malate dehydrogenase0.0000 conserved hypothetical protein0.1103 hypothetical protein0.0494 hypothetical protein0.1577 hypothetical protein0.0464 site-specific recombinase IntIA0.1773 putative inorganic polyphosphate/ATP-NAD kinase0.0000 pyridoxal phosphate biosynthetic protein pdxJ0.0000 putative biopolymer transport protein0.1511 putative tansport related protein0.1175 putative TonB exported protein0.0124 putative ThiJ family intracellular protease/amidase0.0841 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase0.0000 ATP-dependent DNA helicase recG

N/D nucleoside diphosphate kinase0.0767 putative peptidase0.0780 conserved hypothetical protein0.1504 conserved hypothetical protein0.0348 triosephosphate isomerase0.1940 hypothetical protein0.0243 GTP cyclohydrolase I0.0268 DNA primase0.0000 chorismate mutase/prephenate dehydratase (tyrA)0.0000 putative phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase0.0000 aminotransferase0.0000 prephenate dehydratase0.1104 TPR domain-containing protein0.1946 ATP-dependent DNA helicase recQ0.1762 single-stranded-DNA-specific exonuclease recJ0.2305 hypothetical protein0.0577 conserved hypothetical protein0.0448 Thioesterase superfamily protein

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0.0684 conserved hypothetical protein, putative translation factor0.0000 putative chloride channel protein0.0486 methionyl-tRNA formyltransferase0.0000 ribulose-phosphate 3-epimerase0.0000 competence protein0.0000 conserved hypothetical protein, putative exopolyphosphatase-related protein0.0121 conserved hypothetical protein0.0023 phosphoglucomutase/phosphomannomutase0.1586 transcriptional regulator0.0000 SusC homolog0.0857 SusD homolog0.0386 hypothetical protein0.0086 hypothetical protein0.2965 alpha-L-fucosidase-like precursor0.0004 transcriptional regulator0.0714 SusC homolog0.0010 SusD homolog0.0035 alpha-1,2-mannosidase-like protein0.0007 hypothetical protein0.2458 glycoside hydrolase family 920.2545 glycoside hydrolase family 920.1348 putative secretory protein0.0721 putative alpha-1,2-mannosidase0.0760 two-component system response regulator0.1823 putative two-component system sensor protein histidine kinase

N/D cation efflux system protein0.1573 cation efflux system protein, AcrB/AcrD/AcrF family protein0.3135 hypothetical protein0.0346 glutathione peroxidase0.1017 putative NTP pyrophosphohydrolase0.0748 S-adenosylmethionine:tRNA ribosyltransferase-isomerase0.1142 putative AraC-family regulatory protein0.0000 3-dehydroquinate synthase0.0055 conserved hypothetical protein0.0001 TonB-dependent receptor domain protein0.0000 putative cardiolipin synthetase0.1131 putative methyltransferase0.0346 conserved hypothetical protein0.0000 conserved hypothetical protein0.0921 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member0.2540 SusC homolog0.2161 SusD homolog0.2220 conserved hypothetical protein0.2554 putative patatin-like protein

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0.0890 endo-beta-N-acetylglucosaminidase F1 precursor0.1717 putative peptidoglycan bound protein0.3064 hypothetical protein0.0286 putative alpha-1,2-mannosidase0.0233 putative alpha-1,2-mannosidase0.0000 putative anti-sigma factor0.1826 RNA polymerase ECF-type sigma factor0.1318 putative alpha-1,2-mannosidase0.0060 alanyl-tRNA synthetase0.0510 putative peptidase0.0715 transcriptional regulator0.3122 GTP pyrophosphokinase0.0040 membrane-bound lytic murein transglycosylase D presursor0.2305 conserved hypothetical protein0.1128 putative chromosome partitioning protein parB0.0638 ATPase, ParA family0.0609 stationary-phase survival protein SurE0.1255 lipid-A-disaccharide synthase0.1567 conserved hypothetical protein0.1337 phosphatidate cytidylyltransferase0.2871 AAA-metalloprotease FtsH, with ATPase domain

N/D conserved hypothetical protein0.1421 integrase0.0234 conserved hypothetical protein0.0590 DNA-methyltransferase0.0079 putative ABC oligo/dipeptide transport, ATP-binding protein0.0273 restriction endonuclease0.0642 putative type II restriction endonuclease0.0654 transposase0.1258 conserved hypothetical protein

N/D hypothetical protein0.0465 conserved hypothetical protein0.0780 conserved hypothetical protein0.1940 conserved hypothetical protein0.1021 integrase0.0758 integrase0.2470 transposase0.2502 hypothetical protein0.0701 Putative DNA binding protein0.0012 conserved hypothetical protein

N/D hypothetical proteinN/D hypothetical protein

0.1940 hypothetical protein0.0797 hypothetical protein

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N/D N-acetylmuramoyl-L-alanine amidaseN/D conserved hypothetical protein, putative non-specific DNA-binding protein

0.0797 hypothetical protein0.2062 hypothetical protein0.0659 hypothetical protein0.1018 conserved hypothetical protein0.1161 hypothetical protein0.0046 SusD homolog0.0362 SusC homolog0.0890 putative galactose oxidase precursor0.2813 conserved hypothetical protein0.0135 putative Mg2+ transporter MgtE0.1765 dimethyladenosine transferase0.0676 putative dolichol-P-glucose synthetase0.1230 aminoacyl-histidine dipeptidase0.0557 conserved hypothetical protein0.0451 Alpha-2-macroglobulin-like protein0.0000 conserved hypothetical protein0.0000 putative ArgK protein with ATPase and kinase domains0.0243 beta-galactosidase0.0087 putative transmembrane permease0.3143 putative ABC transporter ATP-binding protein0.0851 putative membrane transport protein0.0000 putative transcriptional regulator0.1651 TonB-dependent receptor0.0006 conserved hypothetical protein0.0547 two-component system sensor histidine kinase0.1056 NADH dehydrogenase I, chain N0.2602 NADH dehydrogenase I, chain M0.2451 NADH dehydrogenase I, chain L0.2878 NADH dehydrogenase I, chain K0.0066 NADH dehydrogenase I, chain J0.3074 NADH dehydrogenase I, chain I0.1926 NADH dehydrogenase I, chain H0.1285 NADH dehydrogenase I, chain D0.0765 NADH dehydrogenase I, chain B0.2829 NADH dehydrogenase I, chain A0.2683 conserved hypothetical protein0.0460 conserved hypothetical protein, putative regulatory protein0.1340 RNA polymerase ECF-type sigma factor0.0663 hypothetical protein0.0386 alpha-mannosidase0.0011 Alpha-1,2-mannosidase, putative0.0138 beta-mannosidase precursor

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0.0470 putative lipolytic enzyme, G-D-S-L family0.0292 alpha-rhamnosidase0.0023 endo-1,4-beta-xylanase Z precursor0.1066 Lipolytic enzyme, G-D-S-L family0.2024 conserved hypothetical protein0.1067 putative cell surface protein0.2386 SusC homolog0.1821 SusD homolog0.2080 hypothetical protein0.0018 conserved hypothetical protein0.2834 SusD homolog0.0781 hypothetical protein0.0385 hypothetical protein0.0461 SusC homolog0.1689 SusD homolog0.0262 SusC homolog0.2473 sialic acid-specific 9-O-acetylesterase0.1022 putative alpha-1,2-mannosidase0.0002 alpha-1,2-mannosidase family protein0.0276 glycosidase0.0328 beta-xylosidase (1,4-beta-D-xylan xylosidase)0.0676 lipolytic enzyme, G-D-S-L family0.0096 Trk system K+ uptake protein trkH0.2114 Trk system K+ uptake protein trkA0.2080 1-deoxy-D-xylulose 5-phosphate synthase0.1086 putative lipoprotein0.1038 alanine racemase0.0007 putative Sec-independent protein translocase0.0000 putative Sec-independent protein translocase0.0547 DNA helicase0.2252 hexuronate transporter0.1213 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase0.1202 putative phosphotransferase enzyme II, C component0.0005 glycoside hydrolase family 150.0139 putative pectinesterase precursor0.0001 putative pectinesterase precursor0.0175 two-component system sensor histidine kinase/response regulator, hybrid (one-component system)0.1579 putative Fibronectin0.0505 SusD homolog0.2267 SusC homolog0.2793 pectate lyase0.3059 pectate lyase0.1199 conserved hypothetical protein0.0966 putative two-component system response regulator, no kinase domain

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0.0873 pectate lyase0.1396 Fibronectin, type III0.1028 SusC homolog0.0195 SusD homolog0.2214 exo-poly-alpha-D-galacturonosidase precursor0.0003 two-component system sensor histidine kinase/response regulator, hybrid (one-component system)0.0022 conserved hypothetical protein0.0000 flavoprotein0.0000 glucosamine-6-phosphate isomerase0.1803 putative Sua5/yciO/yrdC family protein0.3023 outer membrane assembly protein0.0074 putative helicase0.0792 putative haloacid dehalogenase-like hydrolase0.0303 putative chitobiase0.1782 hypothetical protein0.0050 SusD homolog0.2615 SusC homolog0.1720 putative exported fucosidase0.2758 two-component system sensor histidine kinase/response regulator, hybrid (one-component system)0.0059 putative aminotransferase0.2676 Metallophosphoesterase0.0804 DNA polymerase, beta-like region

N/D hypothetical protein0.0692 putative AraC family transcriptional regulator0.0003 putative iron-sulfur cluster binding protein

N/D transposase0.0176 Glycoside hydrolase family 2, sugar binding protein0.1820 exo-poly-alpha-D-galacturonosidase precursor0.3140 hypothetical protein0.1940 hypothetical protein0.0532 exo-poly-alpha-D-galacturonosidase precursor

N/D putative rhamnogalacturonan acetylesterase0.0000 beta-glucuronidase0.1504 beta-galactosidase I0.2268 Exopolygalacturonase precursor0.2254 chitin deacetylase0.2861 pectate lyase0.0851 beta-galactosidase0.0325 alpha-galactosidase precursor0.0012 Lipolytic enzyme, G-D-S-L family0.0326 hypothetical protein0.2423 beta-galactosidase precursor

N/D Histone-like bacterial DNA-binding protein0.1373 putative helicase

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0.2032 conserved hypothetical protein0.0036 SusC homolog0.1062 SusD homolog0.1977 putative lipoprotein0.2287 hypothetical protein0.1036 SusC homolog0.2953 SusD homolog0.0005 putative pectate lyase L precursor0.0691 hypothetical protein0.3116 Concanavalin A-like lectin/glucanase0.0001 putative rhamnogalacturonan acetylesterase0.0000 Glycosyl hydrolase, family 880.0001 conserved hypothetical protein0.1632 conserved hypothetical protein, putative cytoplasmic protein0.2681 Rhamnose mutarotase0.0249 two-component system sensor histidine kinase/response regulator, hybrid (one-component system)0.1913 polysaccharide deacetylase0.0038 acetyl xylan esterase A0.0001 beta-galactosidase0.2550 two-component system sensor histidine kinase/response regulator, hybrid (one-component system)0.1363 pectate lyase L precursor0.0747 phosphoglycolate phosphatase0.0000 xylosidase/arabinosidase0.0133 conserved hypothetical protein0.0000 exo-poly-alpha-D-galacturonosidase precursor0.1108 enoyl-[acyl-carrier-protein] reductase0.0454 conserved hypothetical protein0.0593 putative S-adenosylmethionine-dependent methytransferase0.0003 hypothetical protein0.1273 lipoic acid synthetase0.0000 dipeptidyl peptidase IV0.3146 putative integral membrane protein

N/D conserved hypothetical protein0.2227 conserved hypothetical protein0.0150 hypothetical protein0.0667 putative regulatory protein0.2468 putative transcriptional regulator0.0316 putative transcriptional regulator0.0641 putative transcriptional regulator0.0647 hypothetical protein0.0520 tRNA delta(2)-isopentenylpyrophosphate transferase0.0000 conserved hypothetical protein0.0000 acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase0.0000 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase

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0.0626 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase0.0577 phosphohydrolase0.0000 orotidine 5'-phosphate decarboxylase0.2318 peptide chain release factor 10.2355 putative phosphoribosylformylglycinamidine cyclo-ligase0.0681 putative LemA protein0.0048 conserved hypothetical protein0.0196 hydrolase of the alpha/beta superfamily0.0000 shikimate 5-dehydrogenase0.0000 ubiquinone/menaquinone biosynthesis methyltransferase0.0000 phosphoribosylamidoimidazole-succinocarboxamide synthase0.0000 phosphate starvation-inducible protein, PhoH0.0033 conserved hypothetical protein0.0889 flotillin-like protein0.1181 conserved hypothetical protein0.1222 putative cell filamentation protein Fic-related protein

N/D hypothetical protein0.0179 hypothetical protein0.0584 conserved hypothetical protein0.0566 conserved hypothetical protein0.1166 hypothetical protein

N/D hypothetical protein0.1648 putative transcriptional regulator0.0003 putative helicase0.1803 Histone-like bacterial DNA-binding protein0.0692 Lambda repressor-like, DNA-binding protein0.2372 conserved hypothetical protein0.1940 FimX-like protein0.1110 hypothetical protein0.1940 two-component system sensor histidine kinase/response regulator, hybrid (one-component system)0.0113 tRNA pseudouridine synthase A0.0750 putative permease0.1412 conserved hypothetical protein0.2539 conserved hypothetical protein, with a phosphotransferase enzyme family domain0.2862 beta-galactosidase0.0005 putative transporter0.1976 putative oxidoreductase (putative secreted protein)0.0003 conserved hypothetical protein0.1792 conserved hypothetical protein0.0281 SusD homolog0.0861 SusC homolog0.0742 putative anti-sigma factor0.1428 conserved hypothetical protein0.2354 RNA polymerase ECF-type sigma factor

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0.0008 hypothetical protein0.0047 putative oxidoreductase0.0665 6,7-dimethyl-8-ribityllumazine synthase0.1940 putative TPR domain protein0.2473 DNA replication and repair protein RecF, ABC family ATPase

N/D conserved hypothetical protein0.0130 putative histidinol-phosphatase0.1658 putative 5-formyltetrahydrofolate cyclo-ligase0.0000 carboxy-terminal processing protease precursor0.0000 deoxycytidylate deaminase0.0000 hypothetical protein0.0000 peptidyl-dipeptidase0.0687 glyceraldehyde 3-phosphate dehydrogenase0.0258 putative ion channel0.0000 GMP synthase (glutamine-hydrolyzing)0.0582 conserved hypothetical protein with NHL repeat0.0042 SusC homolog0.0206 SusD homolog0.0074 hypothetical protein0.0065 putative chitobiase

N/D hypothetical protein0.1738 hypothetical protein0.0433 conserved hypothetical protein0.1765 hypothetical protein0.2125 hypothetical protein

N/D conserved hypothetical protein, putative transposaseN/D conserved hypothetical proteinN/D transposase

0.0040 conserved hypothetical protein0.1831 glycoside transferase family 40.0390 glycoside transferase family 20.0291 glycoside transferase family 40.0018 conserved hypothetical protein0.2676 hypothetical protein0.0083 hypothetical protein

N/D hypothetical protein0.1808 hypothetical protein0.1837 ABC transporter ATP-binding protein0.1537 putative hemolysin secretion protein

N/D transposaseN/D conserved hypothetical protein

0.0146 putative helicase0.0025 conserved hypothetical protein0.0754 hypothetical protein

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0.2808 putative chitobiase0.0176 MscS mechanosensitive ion channel0.2595 SusD homolog0.3038 SusC homolog0.0673 putative cell surface protein0.0000 transcription regulator, CRP family0.0000 Multiple antibiotic resistance (MarC)-related protein0.1940 putative transmembrane protein0.0000 glycogen debranching enzyme-related protein (4-alpha-glucanotransferase)0.0000 glycoside transferase family 40.0000 putative alpha-amylase0.0000 conserved hypothetical protein0.2616 putative glycogen synthase0.0563 pantoate--beta-alanine ligase0.0464 aspartate 1-decarboxylase precursor0.0987 NADPH-dependent glutamate synthase small chain0.1252 glucose/galactose transporter0.0797 seryl-tRNA synthetase

N/D 50S ribosomal protein L270.2470 50S ribosomal protein L210.0004 HPr(Ser) phosphatase0.0760 putative lipoprotein0.1141 putative lipoprotein protein0.0000 ATP-binding protein0.0443 putative transmembrane protein0.0485 putative zinc protease

N/D 2-dehydro-3-deoxyphosphooctonate aldolaseN/D conserved hypothetical protein, with a diacylglycerol kinase catalytic domain

0.0000 tRNA delta(2)-isopentenylpyrophosphate transferase0.2753 conserved hypothetical protein0.0760 putative efflux ABC transporter, permease protein0.0586 ABC transporter ATP-binding protein0.0074 conserved hypothetical protein0.2495 conserved hypothetical protein0.1972 conserved hypothetical protein with a conserved domain0.2138 xanthosine permease0.1484 putative methyltransferase0.0299 3'-5' exonuclease-like protein0.1171 conserved hypothetical protein0.1257 FtsK/SpoIIIE family protein

N/D conserved hypothetical protein0.0000 thioredoxin reductase0.0081 beta-hexosaminidase precursor0.0000 CRP family transcriptional regulator with cAMP-binding domain

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0.1689 glutamine synthetase0.1262 hypothetical protein0.0049 conserved hypothetical protein0.0088 RNA-directed DNA polymerase0.1303 putative DNA helicase0.2935 conserved hypothetical protein, putative DNA helicase0.2539 30S ribosomal protein S10.0869 conserved hypothetical protein, with a Metallo-beta-lactamase superfamily domain0.2141 RNA polymerase ECF-type sigma factor0.0214 conserved hypothetical protein0.0331 conserved hypothetical protein0.1561 tetrapyrrole methylase family protein/MazG family0.0225 hypothetical protein0.0746 conserved hypothetical protein0.0406 valyl-tRNA synthetase0.1125 two-component system sensor histidine kinase0.1503 RNA polymerase ECF-type sigma factor

N/D putative anti-sigma factor0.0047 SusC homolog0.1214 SusD homolog0.0113 alpha-N-acetylglucosaminidase precursor0.0017 conserved hypothetical protein0.0561 conserved hypothetical protein0.1283 preprotein translocase SecA subunit0.0000 putative alkaline phosphatase0.0000 conserved hypothetical protein, Calycin-like protein0.2836 hypothetical protein0.0691 putative transcription regulator0.2809 putative outer membrane protein0.0450 hypothetical protein0.0016 conserved hypothetical protein0.0308 putative hemolysin0.0000 peptidyl-prolyl cis-trans isomerase0.0687 conserved hypothetical protein0.1959 putative lipoprotein0.2339 4-hydroxythreonine-4-phosphate dehydrogenase0.0370 transcriptional regulator

N/D conserved hypothetical protein0.0001 conserved hypothetical protein0.0298 putative protein-export membrane protein0.3078 putative oxalate:formate antiporter0.0678 conserved hypothetical protein0.0014 hypothetical protein0.0000 conserved hypothetical protein

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0.0770 putative sugar kinaseN/D conserved hypothetical protein

0.0405 di-tripeptide ABC transporter0.0730 hypoxanthine-guanine phosphoribosyltransferase

N/D adenylate kinase (ATP-AMP transphosphatase)0.0004 GTP-binding protein0.0158 conserved hypothetical protein0.0289 conserved hypothetical protein0.0007 putative metalloendopeptidase

N/D putative Tn5 transposase0.0145 hypothetical protein0.0995 beta-hexosaminidase precursor0.0098 hyaluronoglucosaminidase precursor0.0336 transcriptional regulator0.1019 xylose/H+ symporter0.1007 TPR domain-containing protein0.0004 conserved hypothetical protein0.0032 conserved hypothetical protein0.0547 hypothetical protein0.1188 RNA polymerase ECF-type sigma factor0.2829 putative anti-sigma factor0.2803 SusC homolog0.0012 SusD homolog0.0007 putative secreted endoglycosidase0.0000 Concanavalin A-like lectin/glucanase0.0000 conserved hypothetical protein0.0467 DNA damage-inducible protein0.0202 conserved hypothetical protein0.0083 hypothetical protein0.1267 Transglutaminase-like protein0.0285 conserved hypothetical protein0.0690 conserved hypothetical protein0.0117 putative decarboxylase beta subunit0.2521 Cu2+ homeostasis protein CutC0.0537 HD superfamily hydrolase

N/D conserved hypothetical proteinN/D conserved hypothetical protein

0.0559 conserved hypothetical protein, with a conserved domain0.2676 conserved hypothetical protein0.1713 conserved hypothetical protein0.0036 xylulose kinase0.0502 sorbitol dehydrogenase

N/D deoxyribose-phosphate aldolase0.0061 conserved hypothetical protein

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0.0077 putative surface layer protein, with cytochrome c domainN/D conserved hypothetical protein

0.2855 putative pteridine-dependent dioxygenase0.0127 cytochrome c biogenesis protein (ccsA)0.1614 conserved hypothetical protein0.0323 putative non-specific DNA-binding protein HU-10.0000 hypothetical protein

N/D hypothetical protein0.2619 hypothetical protein0.0274 Bacterial Ig-like, group 20.2067 transposase0.0023 hypothetical protein

N/D hypothetical protein0.0147 conserved hypothetical protein, putative cell surface protein0.1857 cell surface protein0.0500 hypothetical protein0.0417 N-acetylmuramoyl alanine amidase0.3097 hypothetical protein0.0115 conserved hypothetical protein0.2172 sugar phosphate isomerase/epimerase0.2609 conserved hypothetical protein0.2747 putative dehydrogenase0.1368 putative dehydrogenase0.2676 conserved hypothetical protein0.0629 putative MTA/SAH nucleosidase0.2123 conserved hypothetical protein0.2782 6-pyruvoyl-tetrahydropterin synthase0.0647 conserved hypothetical protein0.1940 oxidoreductase, putative glycolate oxidase0.1137 putative electron transport protein0.0512 conserved hypothetical protein0.0441 pyridoxine kinase0.2930 conserved hypothetical protein, putative transport protein0.2406 SusC homolog0.0050 RNA polymerase ECF-type sigma factor0.2735 conserved hypothetical protein0.0012 phosphatidate cytidylyltransferase0.1176 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase-related protein0.3080 conserved hypothetical protein, putative outer membrane protein0.0733 hypothetical protein0.3119 hypothetical protein0.0049 conserved hypothetical protein0.0126 conserved hypothetical protein0.0086 SusC homolog

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0.0000 SusD homolog0.0765 conserved hypothetical protein0.0000 putative purine permease0.1145 conserved hypothetical protein0.0029 conserved hypothetical protein0.0009 amino acid carrier protein0.0312 putative ATP-dependent DNA helicase0.2717 hypothetical protein0.0028 integrase protein0.2695 putative cell surface protein0.2501 outer membrane protein0.0080 conserved hypothetical protein0.0477 conserved hypothetical protein0.0000 conserved hypothetical protein0.2366 conserved hypothetical protein0.2566 voltage-gated K+ channel protein0.0047 putative membrane-bound lytic murein transglycosylase0.0357 formamidopyrimidine-DNA glycosylase0.0150 conserved hypothetical protein0.0287 hypothetical protein0.2758 hypothetical protein0.1429 conserved hypothetical protein0.1959 putative sugar nucleotide epimerase0.0842 conserved hypothetical protein0.1773 conserved hypothetical protein0.0269 putative oxidoreductase0.1166 conserved hypothetical protein0.2454 conserved hypothetical protein0.0000 conserved hypothetical protein, putative membrane protein0.2357 hypothetical protein0.0968 ribosomal large subunit pseudouridine synthase A0.0770 conserved hypothetical protein0.0144 conserved hypothetical protein0.0797 Multiple antibiotic resistance (MarC)-related protein0.0002 conserved hypothetical protein0.0010 putative acetyltransferase0.0162 beta-lactamase precursor0.1128 hypothetical protein0.0029 conserved hypothetical protein0.0727 putative helicase0.0002 conserved hypothetical protein0.0300 putative zinc-type alcohol dehydrogenase0.0084 putative rRNA methylase0.1067 Lambda repressor-like, DNA-binding protein

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0.1943 hypothetical protein0.0489 conserved hypothetical protein0.0042 putative type I restriction enzyme BthVORF4518P0.0000 putative type I restriction enzyme M.BthVORF4518P0.0348 conserved hypothetical protein0.0321 putative type I restriction enzyme S.BthVORF4518AP0.2676 integrase0.1940 putative type I restriction enzyme S.BthVORF4518BP0.0000 putative type I restriction enzyme EcoR124II protein0.1470 conserved hypothetical protein0.0765 hypothetical protein0.0695 Metallophosphoesterase0.0002 conserved hypothetical protein0.2803 Metallophosphoesterase0.0021 putative DNA-binding protein0.0000 ATP-dependent DNA helicase recG0.0076 conserved hypothetical protein0.0070 hypothetical protein0.0370 conserved hypothetical protein0.0890 hypothetical protein0.0236 Type I restriction enzyme EcoR124II R protein0.0078 conserved hypothetical protein0.0420 conserved hypothetical protein0.0224 Type I restriction enzyme EcoR124II M protein0.0158 conserved hypothetical protein0.0112 putative Type I restriction enzyme MjaXP specificity protein0.0760 putative Type I restriction modification DNA specificity protein0.0765 Type I restriction enzyme EcoR124II specificity protein0.0176 putative type I restriction enzyme specificity protein0.0000 transposase0.1974 hypothetical protein0.0780 conserved hypothetical protein0.0730 excisionase0.0019 putative protein involved in transposition0.1018 integrase0.0025 putative transposase0.0001 putative GTPase, ThdF family0.2827 two-component system sensor histidine kinase0.0939 NAD-dependent epimerase/dehydratase0.1078 purine nucleoside phosphorylase II0.1771 conserved hypothetical protein0.0677 conserved hypothetical protein0.0000 hypothetical protein0.0117 conserved hypothetical protein

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0.1250 conserved hypothetical protein0.0022 thiamine biosynthesis lipoprotein apbE precursor0.0464 conserved hypothetical protein, putative integral membrane protein0.0000 conserved hypothetical protein0.0000 conserved hypothetical protein0.0001 glycoside transferase family 20.0000 putative transmembrane protein0.2268 two-component system response regulator protein0.0301 putative two-component system sensor0.0165 TonB-dependent receptor0.0000 putative transmembrane protein0.0000 hypothetical protein0.0797 RNA polymerase ECF-type sigma factor0.0578 enolase0.0001 conserved hypothetical protein0.0030 Camphor resistance CrcB protein0.2664 hypothetical protein0.2796 hypothetical protein

N/D hypothetical proteinN/D transposaseN/D hypothetical proteinN/D transposase

0.2161 alpha-glucosidase0.0487 amidophosphoribosyltransferase precursor0.0031 peptidase T (tripeptide aminopeptidase)0.1796 putative aminomethyltransferase0.0470 putative Na+/H+ anitporter0.2956 Histidine triad (HIT) protein0.0187 conserved hypothetical protein

N/D peptidyl-tRNA hydrolase0.0719 putative 50S ribosomal protein L250.1940 conserved hypothetical protein0.0325 putative nitrogen utilization substance protein

N/D conserved hypothetical protein with conserved domain0.0292 conserved hypothetical protein0.0672 putative dephospho-CoA kinase0.0663 conserved hypothetical protein0.0000 conserved hypothetical protein0.0478 endopeptidase Clp ATP-binding chain B0.0974 hypothetical protein0.0122 putative transcriptional regulator0.3189 conserved hypothetical protein0.0112 Histone-like bacterial DNA-binding protein0.2795 chaperone protein dnaK

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0.2955 conserved hypothetical protein0.0043 Phosphatidylinositol transfer protein0.2231 conserved hypothetical protein0.0370 conserved hypothetical protein0.0105 conserved hypothetical protein0.0053 conserved hypothetical protein0.0061 conserved hypothetical protein0.0000 RecA0.0000 putative bacterioferritin co-migratory protein0.0000 Saccharopine dehydrogenase0.0132 conserved hypothetical protein0.1695 conserved hypothetical protein0.2302 chaperone protein dnaK0.1689 hypothetical protein0.1638 integrase0.0760 Putative DNA binding protein0.0130 conserved hypothetical protein0.2121 conserved hypothetical protein0.0781 mobilization protein BmgB0.1002 mobilization protein BmgA0.1707 hypothetical protein0.0797 putative resolvase0.0115 DNA modification methylase BstVI0.0001 conserved hypothetical protein0.1316 DNA modification methylase0.0006 ATP-dependent helicase0.1557 hypothetical protein0.0006 conserved hypothetical protein0.0004 putative arylsulfatase precursor0.0852 putative galactose oxidase precursor0.1707 SusD homolog0.0031 SusC homolog0.0000 putative anti-sigma factor0.0090 RNA polymerase ECF-type sigma factor0.0489 putative inorganic phosphate transporter0.1594 conserved hypothetical protein0.0439 conserved hypothetical protein, putative membrane protein0.0507 conserved hypothetical protein0.0277 putative acetyltransferase0.0000 conserved hypothetical protein0.0538 RNA polymerase ECF-type sigma factor0.0000 putative anti-sigma factor0.1677 SusC homolog0.2724 conserved hypothetical protein

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0.0001 RNA polymerase ECF-type sigma factor0.0293 hypothetical protein0.0000 hypothetical protein0.0105 voltage-gated chloride channel protein0.0091 endonuclease IV0.0961 Oligosaccharide lyase0.3030 glucose/galactose transporter0.2561 ROK family transcriptional repressor, with glucokinase domain0.0026 conserved hypothetical protein0.1827 N-acetylglucosamine-6-sulfatase precursor0.0044 heparinase III protein0.0000 glucuronyl hydrolase0.0000 SusD homolog0.1511 SusC homolog0.0000 hypothetical protein0.0823 heparinase III protein, heparitin sulfate lyase0.0290 two-component system sensor histidine kinase/response0.0258 tryptophan synthase beta chain0.1770 K+ uptake protein0.0588 putative K+ uptake system protein0.0094 beta-galactosidase0.0000 arabinogalactan endo-1,4-beta-galactosidase0.0663 conserved hypothetical protein0.0546 SusD homolog0.0001 SusC homolog0.0625 hypothetical protein0.0519 two-component system sensor histidine kinase0.0498 conserved hypothetical protein0.2130 heparin lyase I precursor0.0427 putative periplasmic protein0.0325 conserved hypothetical protein0.1522 L-serine dehydratase0.2287 Mg2+/Co2+ transport protein0.1940 DNA mismatch repair protein MutS0.0143 beta-hexosaminidase precursor0.0350 glycoside hydrolase family 950.2649 arylsulfatase0.1841 beta-galactosidase0.0417 conserved hypothetical protein0.0014 putative outer membrane protein0.1522 hypothetical protein0.1820 conserved hypothetical protein0.0003 pullulanase precursor0.3022 alpha-amylase precursor

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0.0866 conserved hypothetical protein0.2587 hypothetical protein0.0527 cation efflux system protein0.1756 cation efflux system protein0.2763 outer membrane efflux protein precursor0.0415 conserved hypothetical protein0.0276 transcriptional regulator0.0030 conserved hypothetical protein0.0000 putative hydrolase, haloacid dehalogenase-like hydrolase0.0000 isochorismate synthase entC0.0000 2-oxoglutarate decarboxylase/2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase0.1615 dihydroxynapthoic acid synthetase0.2080 chloromuconate cycloisomerase0.0795 O-succinylbenzoic acid--CoA ligase0.0000 RNA polymerase ECF-type sigma factor0.0296 putative anti-sigma factor0.1025 SusC homolog0.0004 SusD homolog0.0507 glycoside hydrolase family 180.0203 Concanavalin A-like lectin/glucanase0.0092 conserved hypothetical protein0.2502 conserved hypothetical protein0.1408 glycoside hydrolase family 290.2694 periplasmic beta-glucosidase precursor, xylosidase/arabinosidase0.0758 non-specific DNA-binding protein Dps0.3140 redox-sensitive transcriptional activator0.0460 integral membrane protein, putative permease0.0194 putative aquaporin0.0760 conserved hypothetical protein0.2032 putative RNA polymerase ECF-type sigma factor0.0000 conserved hypothetical protein0.1799 RNA polymerase ECF-type sigma factor0.0041 putative anti-sigma factor0.2381 SusC homolog0.1896 SusD homolog0.2819 glycerophosphoryl diester phosphodiesterase0.0770 glycerophosphoryl diester phosphodiesterase0.0007 putative hexose phosphate transport protein

N/D hypothetical protein0.0618 hypothetical protein0.1285 hypothetical protein0.1557 conserved hypothetical protein0.0134 conserved hypothetical protein0.0781 conserved hypothetical protein

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0.0770 Histone-like bacterial DNA-binding protein0.0456 N-acetylmuramoyl-L-alanine amidase0.0108 pyruvate formate-lyase activating enzyme0.0084 formate acetyltransferase0.1765 transposase

N/D transposase0.0000 hypothetical protein

N/D tetracycline resistance element regulator RteB0.1803 hypothetical protein0.0012 putative multiple inositol polyphosphate histidine phosphatase 10.0351 conserved hypothetical protein0.1265 conserved hypothetical protein0.0598 hypothetical protein0.2676 hypothetical protein, helicase-like protein0.0004 putative DNA methylase

N/D hypothetical protein0.0002 conserved hypothetical protein0.2787 conserved hypothetical protein0.0883 Lambda repressor-like, DNA-binding protein0.0370 putative cytosine-specific methyltransferase0.0653 putative two-component system sensor histidine kinase, putative heat shock protein0.0126 hypothetical protein0.0677 hypothetical protein0.2094 putative mobilization protein0.0498 putative mobilization protein

N/D hypothetical proteinN/D conserved protein found in conjugate transposon

0.0130 conserved protein found in conjugate transposon0.0770 conserved protein found in conjugate transposon0.0781 hypothetical protein0.2141 conserved hypothetical protein0.1728 conserved hypothetical protein0.2171 conserved protein found in conjugate transposon0.0780 conserved protein found in conjugate transposon0.2823 conserved protein found in conjugate transposon0.0153 conserved protein found in conjugate transposon0.0670 hypothetical protein

N/D conserved protein found in conjugate transposon0.1940 conserved protein found in conjugate transposon0.0132 conserved protein found in conjugate transposon

N/D conserved protein found in conjugate transposon0.2676 conserved protein found in conjugate transposon0.0760 hypothetical protein0.1765 conserved protein found in conjugate transposon

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N/D conserved protein found in conjugate transposon0.1359 conserved protein found in conjugate transposon

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phosphate-binding periplasmic protein precursor, putative ABC transporter

rteA, two-component system histidine kinase, with response regulator receiver domain

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putative tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase

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putative integral membrane protein, with calcineurin-like phosphoesterase domain

5-methyltetrahydrofolate--homocysteine methyltransferase or methionine synthase

two-component system sensor histidine kinase/response regulator, hybrid (one component system)

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lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex

glutamine ABC transporter, periplasmic glutamine-binding protein (glnH)

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two-component system sensor histidine kinase/response regulator, hybrid (one component system)

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putative UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase

tyrosine-protein kinase ptk involved in exopolysaccharide biosynthesisputative tyrosine-protein kinase in capsular polysaccharide biosynthesis region

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S-layer related protein precursor, sialic acid-specific 9-O-acetylesterase

conserved hypothetical protein, putative S-layer related protein precursor

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Bifunctional purine biosynthesis protein, putative 5-aminoimidazole-4-carboxamide ribonucleotide(AICAR) transformylase/IMP cyclohydrolase

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Na+-transporting NADH:ubiquinone oxidoreductase, Electron transport complex protein rnfBNa+-transporting NADH:ubiquinone oxidoreductase, Electron transport complex protein rnfCNa+-transporting NADH:ubiquinone oxidoreductase, Electron transport complex protein rnfDNa+-transporting NADH:ubiquinone oxidoreductase, Electron transport complex protein rnfGNa+-transporting NADH:ubiquinone oxidoreductase, Electron transport complex protein rnfENa+-transporting NADH:ubiquinone oxidoreductase, Electron transport complex protein rnfA

conserved hypothetical protein, with a conserved domain of unknown function

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cAMP-binding domain (catabolite gene activator) transcriptional regulator

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2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase

1,4-alpha-glucan branching enzyme (isoamylase or pullulanase type II)

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conserved protein with a conserved patatin-like phospholipase domain

integral membrane efflux pump, putative multidrug-efflux transporter

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two-component system sensor histidine kinase/response regulator, hybrid (one component system)

putative outer membrane protein, probably involved in nutrient binding

two-component system sensor histidine kinase/response regulator, hybrid (one component system)

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conserved protein with a conserved patatin-like phospholipase domain

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putative two-component system sensor protein, but no histidine kinase domain

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conserved hypothetical protein, putative TonB-dependent outer membrane receptor protein

conserved hypothetical protein, with a carboxymuconolactone decarboxylase domain

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two-component system sensor histidine kinase/response regulator, hybrid (one component system)

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putative two-component system sensor protein, without kinase domain

conserved hypothetical protein, putative outer membrane efflux protein

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putative endo-beta-N-acetylglucosaminidase F1 precursor (mannosyl-glycoprotein endo-beta-N-acetyl-glucosaminidase F1)

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phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase

phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase

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putative two-component system sensor histidine kinase, no kinase domain

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conserved hypothetical protein, putative regulatory protein with a cAMP-binding domain

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methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase

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two-component system sensor histidine kinase/response regulator, hybrid (one-component system)

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two-component system sensor histidine kinase/response regulator, hybrid (one component system)

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two-component system sensor histidine kinase/response regulator, hybrid (one component system)

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conserved protein, with a weak D-galactarate dehydratase/altronate hydrolase domain

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conserved hypothetical protein, putative non-specific DNA-binding protein

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putative outer membrane protein, probably involved in nutrient binding

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conserved hypothetical protein, with a calcineurin-like phosphoesterase domain

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two-component system sensor histidine kinase/response regulator, hybrid (one component system)

putative membrane transporter involved in nicotinamide mononucleotide transport

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two-component system sensor histidine kinase/response regulator, hybrid (one-component system)

conserved hypothetical protein with endonuclease/exonuclease/phosphatase family domain

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conserved hypothetical protein, serine/threonine kinase pknB-like protein

conserved hypothetical protein, putative membrane-associated protein

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two-component system sensor histidine kinase/response regulator, hybrid (one component system)

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two-component system sensor histidine kinase/response regulator, hybrid (one component system)

putative glycosyltransferase (family 4) involved in lipopolysaccharide biosynthesis

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two-component system sensor histidine kinase/response regulator, hybrid (one-component system)

two-component system sensor histidine kinase/response regulator, hybrid (one-component system)

conserved hypothetical protein, putative cell wall-associated protein precursor

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putative transmembrane transport protein, putative lipopolysaccharide biosynthesis protein

two-component system sensor histidine kinase/response regulator, hybrid (one-component system)

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putative nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferaseFKBP-type peptidyl-prolyl cis-trans isomerase, outer membrane protein precursor

conserved hypothetical protein with relaxase/mobilization nuclease domain

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two-component system sensor histidine kinase/response regulator, hybrid (one-component system)

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putative TIM-barrel enzyme, possible dehydrogenase, contains a highly conserved dihydrouridine synthase domain

two-component system sensor histidine kinase/response regulator, hybrid (one-component system)

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putative proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydraogenase

two-component system sensor histidine kinase/response regulator, hybrid (one-component system)

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two-component system sensor histidine kinase/response regulator, hybrid (one-component system)

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conserved hypothetical protein, putative cell wall associated RhsD protein

conserved hypothetical protein, putative cell wall associated RhsD protein

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two-component system sensor histidine kinase/response regulator, hybrid (one-component system)

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putative nifR3 family TIM-barrel enzyme with dihydrouridine synthase domain

two-component system sensor histidine kinase/response regulator, hybrid (one-component system)

outer membrane protein oprM precursor, multidrug resistance protein

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conserved hypothetical protein, putative ABC transporter permease component

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UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase

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two-component system sensor histidine kinase/response regulator, hybrid (one-component system)

putative outer membrane protein, probably involved in nutrient binding

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ThiF family protein, putative dinucleotide-utilizing enzyme involved in molybdopterin and thiamine biosynthesis

UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase

two-component system sensor histidine kinase/response regulator, hybrid (one-component system)

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two-component system sensor histidine kinase/response regulator, hybrid (one-component system)

endo-beta-N-acetylglucosaminidase F2 precursor (mannosyl-glycoprotein endo-beta-N-acetyl-glucosaminidase F2)

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two-component system sensor histidine kinase/response regulator, hybrid (one-component system)

two-component system sensor histidine kinase/response regulator, hybrid (one-component system)

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phosphoribosylaminoimidazole carboxy formyl formyltransferase; inosine-monophosphate cyclohydrolase; bifunctional purine biosynthesis protein purH

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putative tRNA (5-methylaminomethyl-2-thiouridylate) methyltransferase

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putative phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase

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conserved hypothetical protein, putative exopolyphosphatase-related protein

ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

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conserved hypothetical protein, putative non-specific DNA-binding protein

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two-component system sensor histidine kinase/response regulator, hybrid (one-component system)

putative two-component system response regulator, no kinase domain

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two-component system sensor histidine kinase/response regulator, hybrid (one-component system)

two-component system sensor histidine kinase/response regulator, hybrid (one-component system)

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two-component system sensor histidine kinase/response regulator, hybrid (one-component system)

two-component system sensor histidine kinase/response regulator, hybrid (one-component system)

acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase

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two-component system sensor histidine kinase/response regulator, hybrid (one-component system)

conserved hypothetical protein, with a phosphotransferase enzyme family domain

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glycogen debranching enzyme-related protein (4-alpha-glucanotransferase)

conserved hypothetical protein, with a diacylglycerol kinase catalytic domain

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conserved hypothetical protein, with a Metallo-beta-lactamase superfamily domain

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CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase-related protein

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2-oxoglutarate decarboxylase/2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase

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putative two-component system sensor histidine kinase, putative heat shock protein

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A. Log versus stationary growth in MRS broth.

Statistical method: Cyber-TUp (in Stat): 107Down (in Stat): 255Cutoffs: PPDE(<p) > 0.9

ORF Fold-change (stationary relative to log) pBALAC2494_01650 271.426922363945 0.195419190654217BALAC2494_00125 24.0464218489963 0.0552884164380419BALAC2494_01664 15.4887051502726 0.114341165358887BALAC2494_02003 13.0373150478144 0.137791826325127BALAC2494_00595 11.881439859008 0.0310511581752113BALAC2494_00135 9.73086020054004 0.141965483884331BALAC2494_00398 7.51477566804155 0.159991369570174BALAC2494_00208 7.39250469819997 0.0081238469076741BALAC2494_01182 7.26667401269876 0.0173919259808857BALAC2494_00241 6.99846989476831 0.0505959877067563BALAC2494_01261 6.98328439781913 0.0003101411530342BALAC2494_00068 6.91265766167883 0.151038324149448BALAC2494_00596 6.71378361487048 0.0191822517096361BALAC2494_01312 6.60874770904889 0.0891427526407073BALAC2494_01183 6.60582427616885 0.0093812157921227BALAC2494_01728 6.03172433649174 0.0016228406272125BALAC2494_01311 5.9625640558081 0.142990104790297BALAC2494_01085 5.82787652255357 0.0228811909102807BALAC2494_01126 5.61513335992102 0.148748165832915BALAC2494_01075 5.61084883353048 0.0525587895145738BALAC2494_01450 5.54962314158927 0.0580398534186347BALAC2494_01066 5.51964784408677 0.0855001047467722BALAC2494_00594 5.38919386741268 0.0084486640441306BALAC2494_00999 5.36195652107419 0.0021453859734598BALAC2494_01091 5.33355339362262 0.118958436677377BALAC2494_00929 5.08770566975168 0.150663708357011BALAC2494_01326 4.94779960315769 0.0530401036995074BALAC2494_01670 4.93856272076544 0.0197497749399138BALAC2494_01084 4.92973441203071 0.0041834313191651BALAC2494_01963 4.91687744112258 0.0023322053014006

Table S7. Differentially expressed B. animalis subsp. lactis (CNCM I-2494) genes.

|Fold-change| ≥ 2

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BALAC2494_00646 4.86556825881999 0.123987314131227BALAC2494_01098 4.78745310086591 0.0001643250344507BALAC2494_00345 4.75400425077392 0.123177171008237BALAC2494_01711 4.67127984763487 0.0795927848453125BALAC2494_00475 4.47557485462595 0.0587581414209275BALAC2494_01753 4.30471212420418 0.0025041349367594BALAC2494_01000 4.2745585644731 0.0032225691033376BALAC2494_00897 4.26731511134319 0.0409495882265398BALAC2494_00168 4.25606993332967 0.0433980806744624BALAC2494_01850 4.23384149055317 0.167508294055107BALAC2494_00770 4.17938056882996 0.0443648263284095BALAC2494_01185 4.15656904785761 0.0118593709719403BALAC2494_01184 3.99183643671038 0.0093267145146752BALAC2494_00675 3.89414810647953 0.0397872943854903BALAC2494_02042 3.7865574859136 0.0871680360546065BALAC2494_00676 3.7861464073826 0.0021597282249525BALAC2494_01448 3.6695851919663 0.0077162618265085BALAC2494_00755 3.61789473597922 0.138034063714142BALAC2494_00167 3.61300128270499 0.0263084604013136BALAC2494_00207 3.59158656101686 0.086082588503153BALAC2494_01857 3.54479990565757 0.119099439191334BALAC2494_02009 3.49460690846183 0.0941043444201731BALAC2494_00674 3.37817489282689 0.0025500252218051BALAC2494_00668 3.27079050655755 0.0060158557554235BALAC2494_00427 3.23759784950707 0.0025699282108223BALAC2494_01296 3.1556591259732 0.0671185593401269BALAC2494_00201 3.11862469789664 0.0591876748291847BALAC2494_00977 3.03086564819417 0.0345784462263062BALAC2494_01673 3.01833272802645 0.0354739789923083BALAC2494_00240 2.96844163600942 0.0652335850570087BALAC2494_01073 2.94675750632293 0.0793730089126066BALAC2494_01053 2.89891600837253 0.14053358194925BALAC2494_01709 2.86914110232589 0.0075828156158051BALAC2494_00963 2.84343433667915 0.0044921168340149BALAC2494_00593 2.84008735987837 0.0268353599953189BALAC2494_01427 2.79880033736837 0.0346885555774987BALAC2494_00289 2.75197932474285 0.0012239577155521BALAC2494_01297 2.73812162347535 0.0473156035462525BALAC2494_00124 2.73791188367617 0.0227214276364183BALAC2494_00052 2.73783301232115 0.0021978494047978BALAC2494_00866 2.67576768292956 0.0186727354394103

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BALAC2494_02074 2.60000393781446 0.0427640285798987BALAC2494_00506 2.59425251290062 0.0378517412919359BALAC2494_01760 2.58042669567273 0.0539331684262481BALAC2494_00669 2.5801887324847 0.0040790281122843BALAC2494_01458 2.56797032651186 0.0056716297266669BALAC2494_00670 2.55529429230995 0.0069509879387348BALAC2494_00914 2.51109437147781 0.0294499257950518BALAC2494_00109 2.41555045017166 0.0613415619081733BALAC2494_00466 2.38419972857659 0.0145632869231838BALAC2494_01044 2.37951476826932 0.153957163251699BALAC2494_00469 2.3609154388229 0.051125332825701BALAC2494_00423 2.34883507150807 0.009903992670564BALAC2494_00214 2.34662865859732 0.0175576363146778BALAC2494_00126 2.32708857726813 0.078095710771084BALAC2494_00468 2.32647505821215 0.0790544733070657BALAC2494_00971 2.3215508785668 0.0370204024945939BALAC2494_00496 2.31219440466204 0.150222353752587BALAC2494_01652 2.29750689252058 0.0553304788590525BALAC2494_01201 2.2817769705657 0.0395478826389576BALAC2494_00672 2.26769493848259 0.0106815033716841BALAC2494_01011 2.25719446828742 0.0205785773653722BALAC2494_00218 2.2548243915742 0.013482963497657BALAC2494_00470 2.23471711245198 0.112311675505404BALAC2494_00890 2.18426332009392 0.11437950221742BALAC2494_01086 2.17414406824698 0.0166630974675622BALAC2494_00616 2.17017321024754 0.113900044525534BALAC2494_00912 2.14845046591703 0.0337126737634181BALAC2494_00028 2.14643497871791 0.0707887221787009BALAC2494_00146 2.14633913138904 0.0435237089060568BALAC2494_01447 2.11691867607869 0.0132080026040637BALAC2494_00365 2.11083903009483 0.0597586947282008BALAC2494_00617 2.10163138007996 0.0412141647504702BALAC2494_00847 2.08543255422927 0.0304986390116173BALAC2494_02014 2.08260220768508 0.0561094456077414BALAC2494_00069 2.07479696996279 0.0042922442297604BALAC2494_01703 2.05296143704698 0.0121744270053785BALAC2494_00780 0.496239966033138 0.0142917982012987BALAC2494_00730 0.494406062433984 0.05578232220976BALAC2494_00347 0.493408238162441 0.0322867491335521BALAC2494_00688 0.493359799249032 0.0788612229553067BALAC2494_00185 0.492779618424824 0.110571321290999

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BALAC2494_01792 0.492086250995169 0.0263066002825376BALAC2494_00200 0.487897437516576 0.0149266627328928BALAC2494_00433 0.486850450230578 0.0815295940868794BALAC2494_00153 0.486694171166575 0.0073250809841312BALAC2494_00341 0.485980715535016 0.0251022410819026BALAC2494_00304 0.482854397837714 0.0595108312364172BALAC2494_01705 0.482721302186771 0.094622655218973BALAC2494_00402 0.482219997873367 0.0508578907916968BALAC2494_00835 0.482069507910847 0.0381110437081733BALAC2494_00191 0.481411288095229 0.0401444683491763BALAC2494_00750 0.480906740171786 0.0236977249380863BALAC2494_00537 0.475372782733453 0.0183525738916199BALAC2494_01439 0.474893083021707 0.0437529702177182BALAC2494_00152 0.470174367070998 0.0023459800345156BALAC2494_00555 0.470161002800502 0.0011236825393264BALAC2494_01799 0.463101950653308 0.101021398539784BALAC2494_00666 0.462237700539737 0.0369772566064334BALAC2494_00711 0.462153503959649 0.0106523246545347BALAC2494_01694 0.461633243167556 0.0484731197944521BALAC2494_00435 0.461495398890215 0.101840697888288BALAC2494_00303 0.459818375931038 0.0011440812801062BALAC2494_00386 0.455481926914693 0.0265160459068053BALAC2494_01025 0.455149536859872 0.0227482382053776BALAC2494_00631 0.454667370241905 0.0817270611249445BALAC2494_00678 0.453236275484852 0.0179732319181409BALAC2494_01165 0.45128094828837 0.0410067622791883BALAC2494_00384 0.450804903849595 0.0237016440636799BALAC2494_00334 0.445466395700438 0.0093455836971854BALAC2494_01733 0.442965114636376 0.0289443047410027BALAC2494_00073 0.440498718539046 0.0375364614048428BALAC2494_01883 0.435967189571043 0.01519585323534BALAC2494_00933 0.432762223855397 0.0729651694270401BALAC2494_01222 0.432552510403542 0.0476324120222095BALAC2494_00536 0.432313252392865 0.0233320452962394BALAC2494_00342 0.432227165597903 0.0431534897215032BALAC2494_00305 0.429338701317642 0.0184762047877447BALAC2494_01127 0.426233952788452 0.0243424283578397BALAC2494_00657 0.42526651907511 0.0205750334704056BALAC2494_00348 0.425077084202294 0.0332116083597306BALAC2494_00550 0.422644075075045 0.0135462448797525BALAC2494_01109 0.421202537557976 0.0360827024151714

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BALAC2494_01994 0.417020256029007 0.0874498169514303BALAC2494_00662 0.416918789120479 0.0087433855572097BALAC2494_00612 0.415568407709963 0.0741044914687069BALAC2494_02069 0.411714254383407 0.0229632792615084BALAC2494_01844 0.41096091612953 0.0005474452604882BALAC2494_00781 0.41092908096855 0.0047841222806737BALAC2494_01171 0.405661743874778 0.0331569206179783BALAC2494_00346 0.404091587579183 0.0382069602862183BALAC2494_00708 0.403994223591066 0.0396200153120244BALAC2494_02047 0.403831667082989 0.126424879794461BALAC2494_00385 0.401961311624756 0.0449866997600954BALAC2494_00779 0.399549970901493 0.0059996757614476BALAC2494_01062 0.399526046338128 0.0459915310155613BALAC2494_01665 0.398873131561986 0.0277329386321177BALAC2494_00548 0.3981344403846 0.082874262905603BALAC2494_01695 0.397971104526678 0.0489320378910636BALAC2494_02043 0.394434706732564 0.0300007088561727BALAC2494_00952 0.393791910886639 0.106633199460894BALAC2494_00592 0.391890376680018 0.0324193760828115BALAC2494_01662 0.388765347991125 0.0660971061297173BALAC2494_00113 0.385830454949813 0.0084843409612689BALAC2494_00884 0.38541391155176 0.0422753660325654BALAC2494_01348 0.384429263313582 0.122039494625487BALAC2494_00633 0.381023867966775 0.0325825232404746BALAC2494_01060 0.376885989692558 0.0841534720784194BALAC2494_01774 0.375026696350143 0.0309102670999242BALAC2494_01484 0.373859145212421 0.0006021686239311BALAC2494_01687 0.372631282714332 0.0399548617118374BALAC2494_01068 0.371874856546882 0.0145606335856693BALAC2494_01399 0.370841796636587 0.0530387896209659BALAC2494_01039 0.369691138627546 0.0326132989438432BALAC2494_01479 0.369287082007445 0.0079508439372236BALAC2494_00210 0.368188745449918 0.0169669792165494BALAC2494_00535 0.367312856528278 0.0128944656910437BALAC2494_00258 0.366877640941499 0.0362405517343982BALAC2494_00202 0.359624676297054 0.0082294964497037BALAC2494_01338 0.359209251502118 0.0269001163838325BALAC2494_00898 0.358973288141372 0.030519019368315BALAC2494_00922 0.358646785735285 0.019798247631071BALAC2494_02021 0.356177260027556 0.0020810190375397BALAC2494_02024 0.353485115402167 0.0232751313131248

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BALAC2494_00339 0.351586953251831 0.0183693933993602BALAC2494_00254 0.350263919998846 0.01377658760281BALAC2494_00027 0.348967998724265 0.0222472723569169BALAC2494_00684 0.34832199071646 0.0424367062536302BALAC2494_00253 0.3481879546071 0.0187585897971416BALAC2494_02037 0.347067227025963 0.0310993024596199BALAC2494_00618 0.342368705106948 0.0107001796255006BALAC2494_00064 0.340109955687129 0.0038064296726128BALAC2494_00179 0.339019011378356 0.0108479038327773BALAC2494_01603 0.337780356322724 0.0471627107644885BALAC2494_00639 0.336484585716708 0.0923094960064098BALAC2494_01277 0.335570836776892 0.0511895823221076BALAC2494_00036 0.331814244598301 0.042294485006009BALAC2494_00702 0.329918690473167 0.154040771986359BALAC2494_00031 0.329273289999685 0.0298203820175681BALAC2494_00063 0.327887628071311 0.0343069270027756BALAC2494_01113 0.327874815643075 0.045142849821207BALAC2494_00787 0.326654936552963 0.0297795492554617BALAC2494_01986 0.326062737542894 0.0846040766519887BALAC2494_01195 0.325140834330098 0.0273896095736614BALAC2494_00332 0.323530726167603 0.0290462845438137BALAC2494_02030 0.323278437085068 0.0250225128022304BALAC2494_00476 0.320447724428536 0.0293978018751434BALAC2494_00359 0.320099875401621 0.0386592003690149BALAC2494_01196 0.319095186630926 0.000248084273182BALAC2494_01488 0.316430787417975 0.0375414432445345BALAC2494_01868 0.315995003953482 0.021988465320634BALAC2494_00507 0.3119319621602 0.0530796305474724BALAC2494_00198 0.307345403590047 0.0291116389688998BALAC2494_00065 0.305416734074161 0.0142411339031501BALAC2494_00886 0.304220570423591 0.0264454175076818BALAC2494_00542 0.304217601613374 0.0302007927822976BALAC2494_00257 0.303243704235411 0.0116026987741616BALAC2494_01070 0.303049456457928 0.0065352080580432BALAC2494_00664 0.30249941823019 0.0653141593657983BALAC2494_01257 0.300369949897096 0.0437820247874172BALAC2494_00222 0.299988759579811 0.0336277673713409BALAC2494_00626 0.299887884303161 0.0301760223566574BALAC2494_01024 0.29956908686317 0.0188895445788191BALAC2494_00199 0.299317352981502 0.0215961546834841BALAC2494_00486 0.296786829314814 0.0113807269638575

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BALAC2494_00529 0.296302535074421 0.0801398691378604BALAC2494_02023 0.293593763359264 0.0078109293043246BALAC2494_00306 0.293130805903409 0.0077434443057335BALAC2494_00522 0.292137469175491 0.0198481390770942BALAC2494_00016 0.288488067633106 0.0096004988624416BALAC2494_01344 0.288392728785368 0.100861082106622BALAC2494_00140 0.286654403641548 0.0273623077819184BALAC2494_02076 0.285523117256384 0.0252254195043107BALAC2494_00255 0.284972637100395 0.0136550471157666BALAC2494_01125 0.284155087441962 0.0255107239654564BALAC2494_01572 0.283717425981081 0.0288512232147029BALAC2494_00042 0.283239339799327 0.0187166062022618BALAC2494_00544 0.282968231094374 0.0447521436717717BALAC2494_01258 0.2799175306799 0.0408372111186874BALAC2494_00256 0.279343162195049 0.0275481095659361BALAC2494_01485 0.279118157302854 0.0423947123386222BALAC2494_01908 0.278374942441404 0.0090350812512168BALAC2494_02000 0.278362957619029 0.0149234048400344BALAC2494_00025 0.278011824456011 0.0209630479007767BALAC2494_00006 0.274783443599087 0.0114921427515062BALAC2494_01608 0.274498138646327 0.0097720828975652BALAC2494_01735 0.269116369402663 0.0170943412948656BALAC2494_01428 0.266592989245425 0.0136732661601913BALAC2494_01384 0.2648492951088 0.0199281642499383BALAC2494_01343 0.264125572561655 0.0030865018369028BALAC2494_00252 0.263858910437112 0.0027892750751239BALAC2494_01954 0.262715151900178 0.0487459869602327BALAC2494_00758 0.262287325158864 0.0175196567687976BALAC2494_01194 0.262077951802846 0.0971920991251816BALAC2494_01279 0.25395277750767 0.017197664536571BALAC2494_00097 0.252089566427718 0.0167108033187062BALAC2494_00754 0.248368841698776 0.0084267211459417BALAC2494_00370 0.247890614097632 0.0103639630976609BALAC2494_01805 0.245829424454662 0.0008586756941573BALAC2494_00757 0.243818922779486 0.007801051809903BALAC2494_00360 0.243583902309583 0.0324845095233922BALAC2494_00322 0.242657547126518 0.0435685252237961BALAC2494_01459 0.241462052274001 0.0128455428474488BALAC2494_01362 0.241388639843197 0.0954569264878857BALAC2494_00659 0.239710360702652 0.0016066042931249BALAC2494_01108 0.238184844160238 0.0368598445488446

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BALAC2494_00438 0.235585436839032 0.0166034731645309BALAC2494_00371 0.235179307842493 0.0148082553196452BALAC2494_01984 0.234791080481369 0.0678820549027856BALAC2494_00663 0.234778541889783 0.0319588674250186BALAC2494_01826 0.234611197274974 0.0523138589085916BALAC2494_01785 0.233420421893673 0.165682776249811BALAC2494_00452 0.232525301749311 0.0065505265699714BALAC2494_01637 0.231522374112263 0.0394502512507444BALAC2494_00712 0.229684642413821 0.145138918384606BALAC2494_00362 0.229250877504597 0.0633894418983367BALAC2494_00108 0.229032083244766 0.0144853817030288BALAC2494_01825 0.228390745414082 0.0041316571008194BALAC2494_00931 0.226834771083245 0.0109879961804853BALAC2494_00195 0.225315757409988 0.0079208467989893BALAC2494_00011 0.224676793070013 0.0050492252727583BALAC2494_00640 0.222877452847289 0.0249763253438935BALAC2494_01440 0.214040474359104 0.0007719564048394BALAC2494_00590 0.211141018232273 0.0148894784794353BALAC2494_00003 0.210523486587705 0.0080383900951362BALAC2494_00574 0.209663852008323 0.0133849253413147BALAC2494_01082 0.205528358539049 0.174190725159687BALAC2494_00292 0.20343673960091 0.019431722038881BALAC2494_00658 0.202915099996408 0.0122034311343207BALAC2494_00442 0.201492979196202 0.0116275475865266BALAC2494_00932 0.200159568715201 0.0134244521009184BALAC2494_01918 0.200072890144365 0.0433506982461731BALAC2494_00956 0.199949163103969 0.016416431189307BALAC2494_01473 0.196250441215366 0.0192607795961166BALAC2494_00369 0.19324473487185 0.0351360370755975BALAC2494_00422 0.191571694220729 0.0241031974973811BALAC2494_01094 0.191187106246545 0.0006152054777533BALAC2494_01361 0.190326602247206 0.0685500339942186BALAC2494_00863 0.187836938600881 0.0181045429186422BALAC2494_00556 0.185974889546466 0.0004833434706435BALAC2494_01708 0.184877045526738 0.004951035238455BALAC2494_01071 0.184791301427567 0.0354126717345649BALAC2494_01203 0.183263579608884 0.0432735202734013BALAC2494_01772 0.173000475731347 0.0484554465347589BALAC2494_01380 0.172270707732699 0.0207356784384669BALAC2494_00783 0.171003619614317 0.0118345069920853BALAC2494_00196 0.169570829806705 0.0089671464185237

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BALAC2494_01379 0.168278568781604 0.0118458472572691BALAC2494_01072 0.162907329092103 0.0404418252735481BALAC2494_00561 0.161789900751902 0.0169690763909095BALAC2494_01209 0.155205651468884 0.0089582331494333BALAC2494_02078 0.149571654246786 0.0005867844540575BALAC2494_01923 0.149571654246786 0.0005867844540575BALAC2494_01327 0.14733354634797 0.170131858531868BALAC2494_00232 0.146049587882981 0.0203849588469511BALAC2494_01346 0.145918346382966 0.0439730619287966BALAC2494_01460 0.145811575357617 0.0139301177492788BALAC2494_01775 0.145640614579232 0.155490543638926BALAC2494_02029 0.145585976028582 0.0878324978101408BALAC2494_00811 0.144790346877767 0.205153902011957BALAC2494_01360 0.143457699023961 0.141937624183561BALAC2494_00814 0.140139288011018 0.0669051004154246BALAC2494_00655 0.137512893819524 0.0055197852236801BALAC2494_01700 0.136372348893423 0.118325805648314BALAC2494_00813 0.131596775640978 0.0833993639567892BALAC2494_01145 0.1298028044946 0.0065131701893245BALAC2494_00812 0.126316928724393 0.140609708668265BALAC2494_00260 0.125473784770732 0.0023455391628173BALAC2494_00002 0.12265621712858 0.0162929250602876BALAC2494_01151 0.113952820598711 0.0074498371334818BALAC2494_00194 0.109743602248254 0.0136799113930511BALAC2494_01726 0.108983457328155 0.259527444350821BALAC2494_00560 0.102073853728615 0.0205009418399623BALAC2494_00602 0.0813544446241105 0.0210956472435619BALAC2494_00557 0.0788580395389068 0.0024742990495223BALAC2494_00564 0.0746607669787606 0.016416232559096BALAC2494_01331 0.0727743092890126 0.0638875779731766BALAC2494_01729 0.068039168686552 0.154152361178467BALAC2494_01776 0.0677539318039012 0.193516460164851BALAC2494_02002 0.0666859416335322 0.125756148176803BALAC2494_01144 0.0662929192579544 0.0060054966343843BALAC2494_00563 0.0555110557393001 0.010483368536027BALAC2494_01333 0.0471254760706356 0.307981508184001BALAC2494_00118 0.0360511756281656 0.0164040431084396BALAC2494_01860 0.0354225292385357 0.0163782163167736BALAC2494_01146 0.0272165518524064 0.0166371965039571BALAC2494_01866 0.0263045824746361 0.0136899316527633BALAC2494_01148 0.0231622018528366 3.82E-05

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BALAC2494_02016 0.0228953330913841 0.0663525196458249BALAC2494_01147 0.0168452738786541 0.0027291087795224BALAC2494_01696 0.0118157978472787 0.0170518599676547BALAC2494_01325 0.0118157978472787 0.0170518599676547

Statistical method: Cyber-T69

158Cutoffs:

ORF K numberBALAC2494_00013 12.6911685796436 K00975BALAC2494_00033 4.67641476244181 K07738BALAC2494_00113 2.04389439471307 K01897BALAC2494_00125 95.9345129926331 K00215BALAC2494_00162 9.21534275840741 K00656BALAC2494_00205 2.24463386927281BALAC2494_00244 5.20829513747672 K03564BALAC2494_00323 2.55087847505954BALAC2494_00377 3.23600762013281 K01834BALAC2494_00398 171.604272344801 K03366BALAC2494_00449 3.62309043480917BALAC2494_00532 6.9202868175368 K03595BALAC2494_00609 48.5832380683491 K02026BALAC2494_00610 89.3835978358361 K02025BALAC2494_00611 3.75369242798606 K02529BALAC2494_00614 73.6694610479106 K01805BALAC2494_00632 6.22320577446743 K03548BALAC2494_00636 16.8221031020238 K02026BALAC2494_00637 18.2489779173937 K12308BALAC2494_00638 38.0128773874767 K02027BALAC2494_00700 8.56975063927789 K01881BALAC2494_00703 17.1432363519727BALAC2494_00759 2.3103083162055 K00705BALAC2494_00923 2.95726845172101 K01126BALAC2494_00957 3.74067572322868 K02004BALAC2494_00958 4.04089665358916 K02003BALAC2494_01055 4.12533676260311 K00853

B. In vivo (mouse) versus in vitro (logarithmic phase in MRS) growth.

Up (in vivo):Down (in vivo):

|Fold-change| ≥ 2

Fold-change (d42 in vivo relative to log)

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BALAC2494_01066 14.3170725359887BALAC2494_01085 32.9590362781247BALAC2494_01091 50.3152125731035BALAC2494_01092 20.0691602135099 K07043BALAC2494_01126 17.0649374947878 K10243BALAC2494_01135 3.81969772352007 K03786BALAC2494_01136 3.24703206532547BALAC2494_01156 133.794401441988 K09955BALAC2494_01157 26.634996574081 K03292BALAC2494_01170 6.81559859603992 K02025BALAC2494_01173 5.56258042018613 K00705BALAC2494_01176 2.5731558719024 K10109BALAC2494_01177 3.67445036074497 K10110BALAC2494_01180 3.12671699012657BALAC2494_01188 6.88176945205603 K05349BALAC2494_01204 7.13628014233187BALAC2494_01212 4.38956223690351BALAC2494_01242 10.8495240471071 K01239BALAC2494_01243 14.6441368964157 K08168BALAC2494_01244 9.89307262846103 K00852BALAC2494_01275 2.9191296564426 K03719BALAC2494_01286 2.71479894607618 K01577BALAC2494_01296 111.656709340019 K01239BALAC2494_01297 82.5589623271837 K03446BALAC2494_01326 105.520464915553BALAC2494_01341 3.88985777341459 K03322BALAC2494_01376 3.05657567354062 K00777;K01423BALAC2494_01395 2.51082380542842 K03657BALAC2494_01434 46.1150474987615BALAC2494_01455 3.03375714263414 K07053BALAC2494_01650 770.692637870046BALAC2494_01658 26.9604636929439BALAC2494_01719 13.0948418902592 K08296BALAC2494_01723 2.03340830507926BALAC2494_01769 6.87707492376084BALAC2494_01812 16.7218073572498BALAC2494_01864 6.17115195457598BALAC2494_01933 18.3518110576591BALAC2494_01994 4.0006161673623BALAC2494_02026 2.54268832934606 K00924BALAC2494_02050 12.9163081679127

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BALAC2494_02061 3.29204645671824BALAC2494_00004 0.0777095510327956BALAC2494_00008 0.271059278499995 K00936BALAC2494_00026 0.120115510504281 K03578BALAC2494_00030 0.175230240672949 K03295BALAC2494_00043 0.182108105304014 K01925BALAC2494_00045 0.0949672673184183 K01924BALAC2494_00072 0.0786365386881975BALAC2494_00084 0.100664180781309 K02916BALAC2494_00085 0.0742697708872586 K02887BALAC2494_00090 0.0536515417127101 K06207BALAC2494_00092 0.233160566656243 K04093;K04518BALAC2494_00095 0.232726132854956 K02004BALAC2494_00099 0.178459945128896 K02034BALAC2494_00100 0.105372305077891 K02031;K02032BALAC2494_00129 0.129106533180282 K03466BALAC2494_00136 0.179851423032422 K03070BALAC2494_00158 0.337441889926519 K02072BALAC2494_00165 0.0882858581089754 K03545BALAC2494_00167 0.298444083344738 K01358BALAC2494_00168 0.0982259480534044 K01358BALAC2494_00183 0.080168878970712 K00826BALAC2494_00186 0.157307987991361 K03596BALAC2494_00210 0.0921515955251475 K03311BALAC2494_00214 0.273497906244269BALAC2494_00216 0.0720032948347467 K04759BALAC2494_00218 0.294386804390296 K01744BALAC2494_00227 0.286740393766385 K03823BALAC2494_00229 0.166111676412297 K03723BALAC2494_00238 0.194671656078004 K01752BALAC2494_00239 0.363380683375629 K01802BALAC2494_00264 0.470914239369584 K04761BALAC2494_00274 0.237427748562117 K03701BALAC2494_00281 0.213840293743278 K03075BALAC2494_00290 0.176684433510458 K03686BALAC2494_00295 0.137566390170626 K01868BALAC2494_00305 0.102250514135161 K01903BALAC2494_00308 0.187354299727221 K00602BALAC2494_00310 0.241296264132152 K02074BALAC2494_00319 0.176689387250185 K06188BALAC2494_00326 0.123188712673211

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BALAC2494_00327 0.441297323560314 K01091BALAC2494_00374 0.176384738486398 K01869BALAC2494_00390 0.225631785318693 K03631BALAC2494_00404 0.329701498072166 K00611BALAC2494_00405 0.283341724171424 K00818BALAC2494_00409 0.15634511894502BALAC2494_00411 0.208447799382185 K01889BALAC2494_00422 0.102075868345586BALAC2494_00424 0.232048765482056BALAC2494_00427 0.106618963340714 K03593BALAC2494_00430 0.276126118225344 K02335BALAC2494_00434 0.266279521460266BALAC2494_00440 0.36104672805403 K00837BALAC2494_00450 0.156052118378718BALAC2494_00453 0.210017008559815BALAC2494_00465 0.104239321582217 K01876BALAC2494_00487 0.0886410585126835 K07027BALAC2494_00497 0.233011047156553 K00574BALAC2494_00498 0.25377272497536 K00789BALAC2494_00500 0.259942947945911 K01687BALAC2494_00502 0.0410708609310882 K01955BALAC2494_00505 0.238338087349656 K02356BALAC2494_00510 0.202257494208422 K02992BALAC2494_00512 0.482531004374412 K01620BALAC2494_00522 0.084089752616151 K01952BALAC2494_00540 0.259671597047889 K03711BALAC2494_00547 0.208730139636334 K00680BALAC2494_00583 0.230189508169878 K09812BALAC2494_00593 0.422115969985309BALAC2494_00597 0.205008703996076 K00088BALAC2494_00662 0.131880599237167 K01447BALAC2494_00668 0.429844158511456 K00540BALAC2494_00679 0.230791048674164 K04567BALAC2494_00723 0.192369317749012 K02879BALAC2494_00726 0.0809462529089678 K02952BALAC2494_00727 0.227325717566822 K02919BALAC2494_00728 0.384867541207263 K02518BALAC2494_00730 0.0460832775810916 K03076BALAC2494_00737 0.192635312964929 K02954BALAC2494_00768 0.166451976179678 K02913BALAC2494_00780 0.106240476131299 K02935

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BALAC2494_00782 0.259244739586825 K02077BALAC2494_00785 0.234363665535324 K02038BALAC2494_00790 0.210510188989876 K01243BALAC2494_00792 0.131422680503277 K00680BALAC2494_00794 0.201099145266031 K01372BALAC2494_00812 0.0106985627686309 K11533BALAC2494_00825 0.16150002008585 K02899BALAC2494_00848 0.248633913957818 K02911BALAC2494_00849 0.350460481277024 K03685BALAC2494_00851 0.223170589559206 K01951BALAC2494_00854 0.220312758976037 K03106BALAC2494_00860 0.0967833429713829 K02860BALAC2494_00865 0.154488702012265 K02902BALAC2494_00868 0.0428649286323307BALAC2494_00869 0.0524961608712056 K11358BALAC2494_00876 0.0782019255813473 K01921BALAC2494_00901 0.476596835158946 K03168BALAC2494_00903 0.350272466167675 K01858BALAC2494_00904 0.256494942733306 K05366BALAC2494_00907 0.137001333280311 K00133BALAC2494_00909 0.224183999888468 K00928BALAC2494_00960 0.120797016963489 K03293BALAC2494_00965 0.392089765064488 K03657BALAC2494_00976 0.302367821720572 K00053BALAC2494_00977 0.113549195935951 K08172BALAC2494_00994 0.145529248261368 K01939BALAC2494_01034 0.196417913735176 K01090BALAC2494_01035 0.178852838682486 K03588BALAC2494_01038 0.121739200668453 K08884BALAC2494_01041 0.220056581343468BALAC2494_01048 0.138053733681572 K01867BALAC2494_01050 0.105472979259842BALAC2494_01097 0.252331546630221BALAC2494_01111 0.382320525138101 K06346BALAC2494_01114 0.115263744151652 K03497BALAC2494_01131 0.153411689305942 K07082BALAC2494_01140 0.249309611919047BALAC2494_01184 0.474490371977734 K03686BALAC2494_01209 0.0737869073285662 K01937BALAC2494_01210 0.336666506419447BALAC2494_01215 0.130773999955281 K03549

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BALAC2494_01223 0.0725368569841191 K07011BALAC2494_01225 0.419620088628737 K01990BALAC2494_01234 0.141406221645085BALAC2494_01270 0.227325717607044BALAC2494_01272 0.0501188188412797 K03628BALAC2494_01273 0BALAC2494_01308 0.0558382337398951 K09015BALAC2494_01309 0.0865026886606373 K09013BALAC2494_01310 0.0758036940359503 K11717BALAC2494_01311 0.100435225148121 K04488BALAC2494_01312 0.19273267357491BALAC2494_01323 0.12602574467071 K00003BALAC2494_01330 0.186912256767468 K06287BALAC2494_01346 0 K00012BALAC2494_01364 0.219001590257158BALAC2494_01371 0.301892179223047 K01354BALAC2494_01404 0.186222543577071BALAC2494_01417 0.377741836176973 K01919BALAC2494_01423 0.348553412939531 K06147BALAC2494_01432 0.334422190186577 K03446BALAC2494_01433 0.148596816529322 K02035BALAC2494_01478 0.134792492843769 K00877;K00941BALAC2494_01546 0.458229200915177 K01653BALAC2494_01608 0.106750179947212 K02823BALAC2494_01634 0.483481977925841 K01934BALAC2494_01637 0.0535876630995335 K00849BALAC2494_01665 0.0672764521485793 K01915BALAC2494_01692 0.301351369275317 K00942BALAC2494_01694 0.103603280963162BALAC2494_01790 0BALAC2494_01822 0.45670868148059BALAC2494_01874 0.219824208994842 K01507BALAC2494_01938 0.0818372583287604BALAC2494_01965 0.0902043183593092 K00560BALAC2494_01967 0.0687510268624504 K02950BALAC2494_02079 0.171548023003896

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PPDE(<p) K number0.9231991204016540.93251667572691 K00215

0.9142055269852090.92020804338145

0.933743153495302 K070240.917722091391478 K058080.910693686239194 K033660.93992621277768 K01533

0.935366841653473 K040430.928033362476242 K110680.937728412886853 K036950.9134175705829070.935272914224171 K132880.9217258956615260.933279810939239 K036870.9355780163137690.911587589089553 K044880.9307374579870920.912038108337535 K102430.926041765220679 K047610.9225911998537570.9191106774180760.935241078121715 K015290.93083102783647 K00329

0.9138485420695940.90948499966083

0.9254506103644650.9311600709304530.9307200889602620.94537254750034 K01423

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0.9082823968311250.955706787281926 K002620.9127175099230840.918492858071316 K029090.923831445970403 K040770.929290534169384 K000010.9335263252855450.924169507870306 K086590.925827998345784 K013580.90424424726831

0.922559427277383 K040780.93628189026515 K03713

0.937497285949053 K036860.924717486278112 K013720.9168703977217930.9318645455529820.917933783604179 K020280.909103412135873 K025650.929569224195774 K013580.917366209425995 K071240.911619081972743 K022830.907641654129806

0.93944237050620.939301760536919 K005400.93143866164056 K03593

0.918861609329784 K012390.9210592867588440.926331067240405 K081720.9119683552337180.914700512752381 K036240.907869442177214 K053490.901379041336663 K018040.9212440164389870.928712366361657 K018100.9203758911414450.923188142231020.93747635315756 K037050.92230559740442 K034460.90805722425671 K09686

0.944337412365068 K069040.925213251356597 K00852

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0.9184740798877840.92297064801567

0.9195875826580230.92819722602463 K00540

0.9357683722821840.93698401649621 K10254

0.9230453355889240.9184293756156360.929999488835408 K036960.9005292883494790.9166005456029450.928088601514737 K003820.9289034915723440.914688322876473 K068900.9143830321380570.920716575148862 K011920.900920237808727 K040660.9191925232326770.9110659856410480.9310175818526710.915837904366752 K005670.925640200402075 K017440.907286184580972 K037040.90383466159177

0.925842681728073 K001000.9003039877871380.9194179141961570.908164733286555 K036650.9077574100448230.920606317343995 K020290.91600395138541

0.9210834820225790.924838594924604 K070400.9175802628382240.9384989044375290.9298777856172660.919988888419794 K029350.905393535681418 K030760.913683647949948 K014960.90059256839131 K06889

0.900204630319572 K02968

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0.9146999936829260.91802160709243 K06942

0.906727738995005 K024380.930459515382352 K015200.91123431010505 K016950.91625828420814 K007590.90496355802751 K02221

0.907314841276422 K019400.922463300252746 K018100.905274621698115 K020060.913980164058829 K029060.915633921624389 K019450.909999548020172 K023420.9348877410701220.93834414696675 K035740.90540107970942

0.912014318150673 K077680.928357100731327 K018070.9088465937785110.903679541530534 K008000.945120899892254 K032100.909751275333721 K001470.9132242867369870.900841262630162 K007540.9157691199023540.901769134391625 K01834

0.910940794976 K009690.92197023808641

0.9075761670753750.90305915836095 K01928

0.9285217696682680.900255005621863 K031100.90035312138348

0.911624880595986 K019330.90746989332213 K01696

0.917818137000077 K019030.926008960276366 K018340.9288598055167130.910523653009416 K025000.9173245561321510.914620335224737 K03536

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0.9045320226333950.926613496155091 K014470.903251337074642 K01198;K012090.913259107523105 K024350.942699553166307 K03767

0.9293093596768 K028640.905492783428307 K020260.900391335063119 K016570.902440486275846 K018750.9035341549096440.9015192898209970.93808660735596

0.901867412001902 K016730.907175968966844 K019150.902541304691455 K07173

0.91962682554010.90672548867537 K00995

0.909079229105272 K037120.902956893686058 K018810.9054308328548640.924635107681775 K018970.901213616809189 K026240.903650481355149 K007540.917416227193839 K007860.9134220755656480.9029406448574770.9414698591728420.9234570330976280.932011429031457 K012010.90736976955113 K01714

0.901420240906227 K016640.921414862477405 K018800.912434463839905 K03311

0.9202982613936 K007640.923260993490103 K038260.92076548223335

0.904502335283026 K086810.902029175487048 K069100.91257663666641 K00761

0.9341527198491950.916444819531905 K00765

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0.913561207388549 K017830.925205109743254 K014650.912072806401867 K005640.9022400038340430.918140896695825 K006100.9264885299305860.9232723417836870.930575418678554 K008470.923734973710589 K008680.912378091336903 K037040.9035749405817560.905414244704674 K020350.901429345944343 K039250.90089568530021 K011760.91384455567097 K013560.90128266795158 K07560

0.901395239262924 K034960.902294383604884 K020400.9156097664897560.9096516283608220.908159081174218 K071690.9142075789934370.9005097339286610.910393757422911 K014620.9461796929289040.902400855615373 K000130.92082428386802

0.9223054577500670.90415317616406 K01259

0.917457078691857 K025650.902276950240933 K018850.90920923808487 K01588

0.930981191978811 K007620.937762232959330.9138747145528 K00831

0.9180959848446480.904819934786070.91608656771857 K007600.93096313146353

0.904653994908119 K002860.917580713147905 K01756

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0.9170687811247540.922572176715098 K015230.918845692780202 K019020.907147782150486 K019520.916125832545076 K097610.913167432715835 K036060.905288225542986 K008100.90041426043315 K01874

0.918350856318487 K015910.9001683878055190.900055404260842 K089720.905918693672589 K010000.9040735066756640.9238255178829250.910130595178219 K002260.905637879030143 K031010.9200452991221210.9279188652405840.904411113202489 K019150.926467016957409 K070240.915509696902124 K028230.906558512965776 K020300.91703061291374

0.907957467553997 K032160.92663039557656

0.941613360881925 K006090.92112239535256 K00633

0.911455274530307 K028710.900453925890474 K070560.905269509123847 K10773

0.90654608298 K020350.91666733327346 K04072

0.915004087833352 K069250.9462084503754720.91760720611152 K02996

0.915907683302394 K018970.911306556920299 K009630.91089558817869 K07177

0.915002533205122 K036060.933715091704042 K01784

0.9036902329299 K02914

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0.9049117995238550.91253695623279 K02340

0.9010478491154680.902317572246477 K012270.911800776047572

0.9031795520808 K011740.91747197885047 K01897

0.927152470268106 K008490.91008465314327

0.921623086832154 K000310.905730390444146 K016810.923532838560757 K072840.913043197518919 K047510.918208405063295 K020040.92029025981933 K07736

0.9311328117869070.9369935480924970.90623176104165 K07386

0.9175883157515070.924413451472184 K076850.902533091324697 K005580.918492184044507 K061530.91287386480179 K03439

0.910850162201254 K020080.912260905470299 K033200.9069417981184620.909316448250545 K032930.911692198355717 K011930.918082987802844 K014090.9107036970143070.949600378549187 K03282

0.91832030256680.9191979519028420.94510151765752

0.9175638421529490.924164235319999 K008970.9278552526109460.901836385314833 K035230.920724504467614 K009650.91356504982577 K06901

0.909874237872365 K02479

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0.92510482450716 K034360.923330924888976 K008970.917396131539540.90606901177919 K01937

0.939755104363733 K011870.939755104363733 K011870.910984211227747 K082530.90289377567806 K02050

0.915674682455205 K000120.9098503652786580.90931079278575

0.9057951185665970.902458435790318 K009970.9146521902247510.915723965846695 K01946;K112630.9112280197259160.9106146204139020.913172861900105 K019660.930115020726169 K025650.906788230978108 K115330.9464042118591840.91048684132114

0.942300035073425 K011820.925878645335252 K020030.9000155671508220.914220862809419 K038270.928955964375143 K029090.9302688481259880.917514148224955 K017390.902314548434602 K018970.9095955730528420.914675625203045 K033280.9194633658310560.934476630407908 K074070.919934060806422 K016970.900112491123456 K129900.937975949374914 K074850.938796120695313 K074850.935945821112684 K101170.933238532775865 K074850.94575374318927 K10119

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0.9257229993564360.939508201423607 K101180.925045429342778 K074850.925045429342778 K07485

Annotation Annotation Sourceglucose-1-phosphate adenylyltransferase [EC:2.7.7.27] KEGG GENES v54

transcriptional repressor NrdR KEGG GENES v54long-chain acyl-CoA synthetase [EC:6.2.1.3] KEGG GENES v54dihydrodipicolinate reductase [EC:1.3.1.26] KEGG GENES v54formate C-acetyltransferase [EC:2.3.1.54] KEGG GENES v54

Unknown KEGG GENES v54peroxiredoxin Q/BCP [EC:1.11.1.15] KEGG GENES v54

Unknown KEGG GENES v54phosphoglycerate mutase [EC:5.4.2.1] KEGG GENES v54

acetoin dehydrogenase [EC:1.1.1.5] KEGG GENES v54Unknown KEGG GENES v54

GTP-binding protein Era KEGG GENES v54multiple sugar transport system permease protein KEGG GENES v54multiple sugar transport system permease protein KEGG GENES v54

LacI family transcriptional regulator KEGG GENES v54xylose isomerase [EC:5.3.1.5] KEGG GENES v54

putative permease KEGG GENES v54multiple sugar transport system permease protein KEGG GENES v54

beta-galactosidase [EC:3.2.1.23] KEGG GENES v54multiple sugar transport system substrate-binding protein KEGG GENES v54

prolyl-tRNA synthetase [EC:6.1.1.15] KEGG GENES v54Unknown KEGG GENES v54

4-alpha-glucanotransferase [EC:2.4.1.25] KEGG GENES v54glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46] KEGG GENES v54

ABC.CD.P KEGG GENES v54ABC.CD.A KEGG GENES v54

L-ribulokinase [EC:2.7.1.16] KEGG GENES v54

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Unknown KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54K07043 KEGG GENES v54

cellobiose transport system ATP-binding protein KEGG GENES v543-dehydroquinate dehydratase II [EC:4.2.1.10] KEGG GENES v54

Unknown KEGG GENES v54hypothetical protein KEGG GENES v54

glycoside/pentoside/hexuronide:cation symporter, GPH family KEGG GENES v54multiple sugar transport system permease protein KEGG GENES v54

4-alpha-glucanotransferase [EC:2.4.1.25] KEGG GENES v54maltose/maltodextrin transport system permease protein KEGG GENES v54maltose/maltodextrin transport system permease protein KEGG GENES v54

Unknown KEGG GENES v54beta-glucosidase [EC:3.2.1.21] KEGG GENES v54

Unknown KEGG GENES v54Unknown KEGG GENES v54

purine nucleosidase [EC:3.2.2.1] KEGG GENES v54MFS transporter, DHA2 family, metal-tetracycline-proton antiporter KEGG GENES v54

ribokinase [EC:2.7.1.15] KEGG GENES v54Lrp/AsnC family transcriptional regulator, leucine-responsive KEGG GENES v54

oxalyl-CoA decarboxylase [EC:4.1.1.8] KEGG GENES v54purine nucleosidase [EC:3.2.2.1] KEGG GENES v54

MFS transporter, DHA2 family, multidrug resistance protein B KEGG GENES v54Unknown KEGG GENES v54

manganese transport protein KEGG GENES v54NOT DEFINED|NOT DEFINED KEGG GENES v54

DNA helicase II / ATP-dependent DNA helicase PcrA [EC:3.6.1.-] KEGG GENES v54Unknown KEGG GENES v54K07053 KEGG GENES v54

Unknown KEGG GENES v54Unknown KEGG GENES v54

phosphohistidine phosphatase [EC:3.1.3.-] KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54

NOT DEFINED KEGG GENES v54Unknown KEGG GENES v54

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Unknown KEGG GENES v54Unknown KEGG GENES v54

NOT DEFINED KEGG GENES v54ATP-dependent helicase HrpA [EC:3.6.1.-] KEGG GENES v54cation efflux system protein, CDF family KEGG GENES v54

UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] KEGG GENES v54UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] KEGG GENES v54

Unknown KEGG GENES v54large subunit ribosomal protein L35 KEGG GENES v54large subunit ribosomal protein L20 KEGG GENES v54

GTP-binding protein KEGG GENES v54chorismate mutase [EC:5.4.99.5]|prephenate dehydratase [EC:4.2.1.51] KEGG GENES v54

ABC.CD.P KEGG GENES v54peptide/nickel transport system permease protein KEGG GENES v54

peptide/nickel transport system ATP-binding protein|peptide/nickel transport system ATP-binding proteinKEGG GENES v54DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family KEGG GENES v54

preprotein translocase subunit SecA KEGG GENES v54D-methionine transport system permease protein KEGG GENES v54

trigger factor KEGG GENES v54ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] KEGG GENES v54ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] KEGG GENES v54

branched-chain amino acid aminotransferase [EC:2.6.1.42] KEGG GENES v54GTP-binding protein LepA KEGG GENES v54

branched-chain amino acid:cation transporter, LIVCS family KEGG GENES v54Unknown KEGG GENES v54

ferrous iron transport protein B KEGG GENES v54aspartate ammonia-lyase [EC:4.3.1.1] KEGG GENES v54

phosphinothricin acetyltransferase [EC:2.3.1.183] KEGG GENES v54transcription-repair coupling factor (superfamily II helicase) KEGG GENES v54

L-serine dehydratase [EC:4.3.1.17] KEGG GENES v54peptidylprolyl isomerase [EC:5.2.1.8] KEGG GENES v54

LysR family transcriptional regulator, hydrogen peroxide-inducible KEGG GENES v54excinuclease ABC subunit A KEGG GENES v54

preprotein translocase subunit SecG KEGG GENES v54molecular chaperone DnaJ KEGG GENES v54

threonyl-tRNA synthetase [EC:6.1.1.3] KEGG GENES v54succinyl-CoA synthetase beta subunit [EC:6.2.1.5] KEGG GENES v54

phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP KEGG GENES v54zinc/manganese transport system ATP-binding protein KEGG GENES v54

aquaporin Z KEGG GENES v54Unknown KEGG GENES v54

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phosphoglycolate phosphatase [EC:3.1.3.18] KEGG GENES v54leucyl-tRNA synthetase [EC:6.1.1.4] KEGG GENES v54

DNA repair protein RecN (Recombination protein N) KEGG GENES v54ornithine carbamoyltransferase [EC:2.1.3.3] KEGG GENES v54

acetylornithine aminotransferase [EC:2.6.1.11] KEGG GENES v54Unknown KEGG GENES v54

phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54

ATP-binding protein involved in chromosome partitioning KEGG GENES v54DNA polymerase I [EC:2.7.7.7] KEGG GENES v54

Unknown KEGG GENES v54NOT DEFINED KEGG GENES v54

Unknown KEGG GENES v54Unknown KEGG GENES v54

aspartyl-tRNA synthetase [EC:6.1.1.12] KEGG GENES v54K07027 KEGG GENES v54

cyclopropane-fatty-acyl-phospholipid synthase [EC:2.1.1.79] KEGG GENES v54S-adenosylmethionine synthetase [EC:2.5.1.6] KEGG GENES v54

dihydroxy-acid dehydratase [EC:4.2.1.9] KEGG GENES v54carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] KEGG GENES v54

elongation factor EF-P KEGG GENES v54small subunit ribosomal protein S7 KEGG GENES v54

threonine aldolase [EC:4.1.2.5] KEGG GENES v54phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] KEGG GENES v54

Fur family transcriptional regulator, ferric uptake regulator KEGG GENES v54NOT DEFINED KEGG GENES v54

cell division transport system ATP-binding protein KEGG GENES v54Unknown KEGG GENES v54

IMP dehydrogenase [EC:1.1.1.205] KEGG GENES v54N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] KEGG GENES v54

NOT DEFINED KEGG GENES v54lysyl-tRNA synthetase, class II [EC:6.1.1.6] KEGG GENES v54

large subunit ribosomal protein L17 KEGG GENES v54small subunit ribosomal protein S13 KEGG GENES v54large subunit ribosomal protein L36 KEGG GENES v54

translation initiation factor IF-1 KEGG GENES v54preprotein translocase subunit SecY KEGG GENES v54small subunit ribosomal protein S14 KEGG GENES v54large subunit ribosomal protein L33 KEGG GENES v54

large subunit ribosomal protein L7/L12 KEGG GENES v54

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zinc/manganese transport system substrate-binding protein KEGG GENES v54phosphate transport system permease protein KEGG GENES v54

S-adenosylhomocysteine/5'-methylthioadenosine nucleosidase KEGG GENES v54NOT DEFINED KEGG GENES v54

bleomycin hydrolase [EC:3.4.22.40] KEGG GENES v54fatty acid synthase, bacteria type [EC:2.3.1.-] KEGG GENES v54

large subunit ribosomal protein L27 KEGG GENES v54large subunit ribosomal protein L32 KEGG GENES v54

ribonuclease III [EC:3.1.26.3] KEGG GENES v54GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] KEGG GENES v54

signal recognition particle subunit SRP54 KEGG GENES v5416S rRNA processing protein RimM KEGG GENES v54large subunit ribosomal protein L28 KEGG GENES v54

Unknown KEGG GENES v54aspartate aminotransferase [EC:2.6.1.1] KEGG GENES v54D-alanine-D-alanine ligase [EC:6.3.2.4] KEGG GENES v54

DNA topoisomerase I [EC:5.99.1.2] KEGG GENES v54myo-inositol-1-phosphate synthase [EC:5.5.1.4] KEGG GENES v54penicillin-binding protein 1A [EC:2.4.1.- 3.4.-.-] KEGG GENES v54

aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] KEGG GENES v54aspartate kinase [EC:2.7.2.4] KEGG GENES v54

amino acid transporter, AAT family KEGG GENES v54DNA helicase II / ATP-dependent DNA helicase PcrA [EC:3.6.1.-] KEGG GENES v54

ketol-acid reductoisomerase [EC:1.1.1.86] KEGG GENES v54MFS transporter, MHS family, shikimate and dehydroshikimate KEGG GENES v54

adenylosuccinate synthase [EC:6.3.4.4] KEGG GENES v54protein phosphatase [EC:3.1.3.16] KEGG GENES v54

cell division protein FtsW KEGG GENES v54serine/threonine protein kinase, bacterial [EC:2.7.11.1] KEGG GENES v54

Unknown KEGG GENES v54tryptophanyl-tRNA synthetase [EC:6.1.1.2] KEGG GENES v54

Unknown KEGG GENES v54Unknown KEGG GENES v54

spoIIIJ-associated protein KEGG GENES v54chromosome partitioning protein, ParB family KEGG GENES v54

K07082 KEGG GENES v54Unknown KEGG GENES v54

molecular chaperone DnaJ KEGG GENES v54CTP synthase [EC:6.3.4.2] KEGG GENES v54

Unknown KEGG GENES v54KUP system potassium uptake protein KEGG GENES v54

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K07011 KEGG GENES v54ABC-2 type transport system ATP-binding protein KEGG GENES v54

Unknown KEGG GENES v54Unknown KEGG GENES v54

transcription termination factor Rho KEGG GENES v54Unknown KEGG GENES v54

Fe-S cluster assembly protein SufD KEGG GENES v54Fe-S cluster assembly ATP-binding protein KEGG GENES v54

cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16] KEGG GENES v54nitrogen fixation protein NifU and related proteins KEGG GENES v54

Unknown KEGG GENES v54homoserine dehydrogenase [EC:1.1.1.3] KEGG GENES v54

septum formation protein KEGG GENES v54UDPglucose 6-dehydrogenase [EC:1.1.1.22] KEGG GENES v54

Unknown KEGG GENES v54oligopeptidase B [EC:3.4.21.83] KEGG GENES v54

Unknown KEGG GENES v54glutamate--cysteine ligase [EC:6.3.2.2] KEGG GENES v54

ATP-binding cassette, subfamily B, bacterial KEGG GENES v54MFS transporter, DHA2 family, multidrug resistance protein B KEGG GENES v54

peptide/nickel transport system substrate-binding protein KEGG GENES v54hydroxymethylpyrimidine kinase [EC:2.7.1.49]|phosphomethylpyrimidine kinase [EC:2.7.4.7]KEGG GENES v54

acetolactate synthase I/III small subunit [EC:2.2.1.6] KEGG GENES v54dihydroorotate dehydrogenase electron transfer subunit KEGG GENES v54

5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] KEGG GENES v54galactokinase [EC:2.7.1.6] KEGG GENES v54

glutamine synthetase [EC:6.3.1.2] KEGG GENES v54guanylate kinase [EC:2.7.4.8] KEGG GENES v54

Unknown KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54

inorganic pyrophosphatase [EC:3.6.1.1] KEGG GENES v54Unknown KEGG GENES v54

thymidylate synthase [EC:2.1.1.45] KEGG GENES v54small subunit ribosomal protein S12 KEGG GENES v54

Unknown KEGG GENES v54

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Annotation Annotation SourceUnknown KEGG GENES v54dihydrodipicolinate reductase [EC:1.3.1.26] KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54K07024 KEGG GENES v54putative sigma-54 modulation protein KEGG GENES v54acetoin dehydrogenase [EC:1.1.1.5] KEGG GENES v54Cu2+-exporting ATPase [EC:3.6.3.4] KEGG GENES v54molecular chaperone DnaK KEGG GENES v54hemolysin III KEGG GENES v54ATP-dependent Clp protease ATP-binding subunit ClpB KEGG GENES v54Unknown KEGG GENES v54oligoribonuclease [EC:3.1.-.-] KEGG GENES v54Unknown KEGG GENES v54molecular chaperone GrpE KEGG GENES v54Unknown KEGG GENES v54nitrogen fixation protein NifU and related proteins KEGG GENES v54Unknown KEGG GENES v54cellobiose transport system ATP-binding protein KEGG GENES v54LysR family transcriptional regulator, hydrogen peroxide-inducible KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54NOT DEFINED KEGG GENES v54NADH dehydrogenase [EC:1.6.5.3] KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54NOT DEFINED KEGG GENES v54

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Unknown KEGG GENES v54glutamate dehydrogenase (NADP+) [EC:1.4.1.4] KEGG GENES v54Unknown KEGG GENES v54large subunit ribosomal protein L31 KEGG GENES v54chaperonin GroEL KEGG GENES v54alcohol dehydrogenase [EC:1.1.1.1] KEGG GENES v54Unknown KEGG GENES v54dipeptidase A [EC:3.4.-.-] KEGG GENES v54ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] KEGG GENES v54Unknown KEGG GENES v54chaperonin GroES KEGG GENES v54MerR family transcriptional regulator, glutamine synthetase KEGG GENES v54molecular chaperone DnaJ KEGG GENES v54bleomycin hydrolase [EC:3.4.22.40] KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54polar amino acid transport system ATP-binding protein [EC:3.6.3.21] KEGG GENES v54N-acetylglucosamine repressor KEGG GENES v54ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] KEGG GENES v54K07124 KEGG GENES v54pilus assembly protein CpaF KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54NOT DEFINED KEGG GENES v54ATP-binding protein involved in chromosome partitioning KEGG GENES v54purine nucleosidase [EC:3.2.2.1] KEGG GENES v54Unknown KEGG GENES v54MFS transporter, MHS family, shikimate and dehydroshikimate KEGG GENES v54Unknown KEGG GENES v54transcription elongation factor GreA KEGG GENES v54beta-glucosidase [EC:3.2.1.21] KEGG GENES v54L-arabinose isomerase [EC:5.3.1.4] KEGG GENES v54Unknown KEGG GENES v54glucose-6-phosphate isomerase [EC:5.3.1.9] KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54heat-inducible transcriptional repressor KEGG GENES v54MFS transporter, DHA2 family, multidrug resistance protein B KEGG GENES v54antibiotic transport system permease protein KEGG GENES v54K06904 KEGG GENES v54ribokinase [EC:2.7.1.15] KEGG GENES v54

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Unknown KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54NOT DEFINED KEGG GENES v54Unknown KEGG GENES v54myosin-crossreactive antigen KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54ATP-dependent Clp protease ATP-binding subunit ClpC KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54dihydrolipoamide dehydrogenase [EC:1.8.1.4] KEGG GENES v54Unknown KEGG GENES v54K06890 KEGG GENES v54Unknown KEGG GENES v54beta-mannosidase [EC:3.2.1.25] KEGG GENES v54primosomal protein N' (replication factor Y) (superfamily II KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] KEGG GENES v54aspartate ammonia-lyase [EC:4.3.1.1] KEGG GENES v54cold shock protein (beta-ribbon, CspA family) KEGG GENES v54Unknown KEGG GENES v54NOT DEFINED KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54GTP-binding protein HflX KEGG GENES v54Unknown KEGG GENES v54polar amino acid transport system permease protein KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54K07040 KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54large subunit ribosomal protein L7/L12 KEGG GENES v54preprotein translocase subunit SecY KEGG GENES v54phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19] KEGG GENES v54K06889 KEGG GENES v54small subunit ribosomal protein S20 KEGG GENES v54

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Unknown KEGG GENES v54K06942 KEGG GENES v54glycogen operon protein GlgX [EC:3.2.1.-] KEGG GENES v54dUTP pyrophosphatase [EC:3.6.1.23] KEGG GENES v54tryptophan synthase alpha chain [EC:4.2.1.20] KEGG GENES v54adenine phosphoribosyltransferase [EC:2.4.2.7] KEGG GENES v54YggT family protein KEGG GENES v54argininosuccinate synthase [EC:6.3.4.5] KEGG GENES v54glucose-6-phosphate isomerase [EC:5.3.1.9] KEGG GENES v54cobalt/nickel transport system ATP-binding protein KEGG GENES v54large subunit ribosomal protein L3 KEGG GENES v54phosphoribosylamine--glycine ligase [EC:6.3.4.13] KEGG GENES v54DNA polymerase III subunit epsilon [EC:2.7.7.7] KEGG GENES v54Unknown KEGG GENES v547,8-dihydro-8-oxoguanine triphosphatase [EC:3.6.1.-] KEGG GENES v54Unknown KEGG GENES v54two-component system, OmpR family, sensor histidine kinase SenX3 KEGG GENES v54ribose 5-phosphate isomerase A [EC:5.3.1.6] KEGG GENES v54Unknown KEGG GENES v543-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19] KEGG GENES v54preprotein translocase subunit YajC KEGG GENES v54glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] KEGG GENES v54Unknown KEGG GENES v54NOT DEFINED KEGG GENES v54Unknown KEGG GENES v54phosphoglycerate mutase [EC:5.4.2.1] KEGG GENES v54nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18] KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligas KEGG GENES v54Unknown KEGG GENES v54fused signal recognition particle receptor KEGG GENES v54Unknown KEGG GENES v54phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] KEGG GENES v54tryptophan synthase beta chain [EC:4.2.1.20] KEGG GENES v54succinyl-CoA synthetase beta subunit [EC:6.2.1.5] KEGG GENES v54phosphoglycerate mutase [EC:5.4.2.1] KEGG GENES v54Unknown KEGG GENES v54cyclase HisF [EC:4.1.3.-] KEGG GENES v54Unknown KEGG GENES v54ribonuclease P protein component [EC:3.1.26.5] KEGG GENES v54

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Unknown KEGG GENES v54N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] KEGG GENES v54xylan 1,4-beta-xylosidase [EC:3.2.1.37]|alpha-N-arabinofuranosidase [ KEGG GENES v54aspartyl-tRNA(Asn)/glutamyl-tRNA (Gln) amidotransferase subunit C KEGG GENES v54peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] KEGG GENES v54large subunit ribosomal protein L10 KEGG GENES v54multiple sugar transport system permease protein KEGG GENES v54anthranilate synthase component I [EC:4.1.3.27] KEGG GENES v54seryl-tRNA synthetase [EC:6.1.1.11] KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54carbonic anhydrase [EC:4.2.1.1] KEGG GENES v54glutamine synthetase [EC:6.3.1.2] KEGG GENES v54S-ribosylhomocysteine lyase [EC:4.4.1.21] KEGG GENES v54Unknown KEGG GENES v54CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase KEGG GENES v54MarR family transcriptional regulator KEGG GENES v54prolyl-tRNA synthetase [EC:6.1.1.15] KEGG GENES v54Unknown KEGG GENES v54long-chain acyl-CoA synthetase [EC:6.2.1.3] KEGG GENES v54IclR family transcriptional regulator, pca regulon regulatory KEGG GENES v54NOT DEFINED KEGG GENES v54NOT DEFINED KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54glucosylceramidase [EC:3.2.1.45] KEGG GENES v54dihydrodipicolinate synthase [EC:4.2.1.52] KEGG GENES v54para-aminobenzoate synthetase component II [EC:2.6.1.85] KEGG GENES v54glycyl-tRNA synthetase [EC:6.1.1.14] KEGG GENES v54branched-chain amino acid:cation transporter, LIVCS family KEGG GENES v54amidophosphoribosyltransferase [EC:2.4.2.14] KEGG GENES v54putative acetyltransferase [EC:2.3.1.-] KEGG GENES v54Unknown KEGG GENES v54glutamine amidotransferase [EC:2.6.-.-] KEGG GENES v54K06910 KEGG GENES v54uracil phosphoribosyltransferase [EC:2.4.2.9] KEGG GENES v54Unknown KEGG GENES v54ATP phosphoribosyltransferase [EC:2.4.2.17] KEGG GENES v54

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ribulose-phosphate 3-epimerase [EC:5.1.3.1] KEGG GENES v54dihydroorotase [EC:3.5.2.3] KEGG GENES v54ribosomal RNA small subunit methyltransferase C [EC:2.1.1.52] KEGG GENES v54Unknown KEGG GENES v54aspartate carbamoyltransferase regulatory subunit KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54fructokinase [EC:2.7.1.4] KEGG GENES v54pyridoxine kinase [EC:2.7.1.35] KEGG GENES v54cold shock protein (beta-ribbon, CspA family) KEGG GENES v54Unknown KEGG GENES v54peptide/nickel transport system substrate-binding protein KEGG GENES v54MraZ protein KEGG GENES v54alpha-amylase [EC:3.2.1.1] KEGG GENES v54repressor LexA [EC:3.4.21.88] KEGG GENES v54D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-] KEGG GENES v54chromosome partitioning protein KEGG GENES v54phosphate transport system substrate-binding protein KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54FHA domain-containing protein KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54NOT DEFINED KEGG GENES v54Unknown KEGG GENES v54histidinol dehydrogenase [EC:1.1.1.23] KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54proline iminopeptidase [EC:3.4.11.5] KEGG GENES v54N-acetylglucosamine repressor KEGG GENES v54glutamyl-tRNA synthetase [EC:6.1.1.17] KEGG GENES v545-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] KEGG GENES v54orotate phosphoribosyltransferase [EC:2.4.2.10] KEGG GENES v54Unknown KEGG GENES v54phosphoserine aminotransferase [EC:2.6.1.52] KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54hypoxanthine phosphoribosyltransferase [EC:2.4.2.8] KEGG GENES v54Unknown KEGG GENES v54pyrroline-5-carboxylate reductase [EC:1.5.1.2] KEGG GENES v54adenylosuccinate lyase [EC:4.3.2.2] KEGG GENES v54

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Unknown KEGG GENES v54phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31] KEGG GENES v54succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] KEGG GENES v54phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] KEGG GENES v54ribosomal RNA small subunit methyltransferase E [EC:2.1.1.-] KEGG GENES v54putative colanic acid biosysnthesis UDP-glucose lipid carrier KEGG GENES v54NOT DEFINED KEGG GENES v54methionyl-tRNA synthetase [EC:6.1.1.10] KEGG GENES v54orotidine-5'-phosphate decarboxylase [EC:4.1.1.23] KEGG GENES v54Unknown KEGG GENES v54putative membrane protein KEGG GENES v54phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54dihydroorotate oxidase [EC:1.3.3.1] KEGG GENES v54signal peptidase II [EC:3.4.23.36] KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54glutamine synthetase [EC:6.3.1.2] KEGG GENES v54K07024 KEGG GENES v54dihydroorotate dehydrogenase electron transfer subunit KEGG GENES v54polar amino acid transport system substrate-binding protein KEGG GENES v54Unknown KEGG GENES v54RNA methyltransferase, TrmH family, group 2 [EC:2.1.1.-] KEGG GENES v54Unknown KEGG GENES v54aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] KEGG GENES v54galactoside O-acetyltransferase [EC:2.3.1.18] KEGG GENES v54large subunit ribosomal protein L13 KEGG GENES v54K07056 KEGG GENES v54endonuclease III [EC:4.2.99.18] KEGG GENES v54peptide/nickel transport system substrate-binding protein KEGG GENES v54acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 KEGG GENES v54K06925 KEGG GENES v54Unknown KEGG GENES v54small subunit ribosomal protein S9 KEGG GENES v54long-chain acyl-CoA synthetase [EC:6.2.1.3] KEGG GENES v54UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] KEGG GENES v54PDZ domain-containing protein KEGG GENES v54putative colanic acid biosysnthesis UDP-glucose lipid carrier KEGG GENES v54UDP-glucose 4-epimerase [EC:5.1.3.2] KEGG GENES v54large subunit ribosomal protein L34 KEGG GENES v54

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Unknown KEGG GENES v54DNA polymerase III subunit delta [EC:2.7.7.7] KEGG GENES v54Unknown KEGG GENES v54mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase KEGG GENES v54Unknown KEGG GENES v54micrococcal nuclease [EC:3.1.31.1] KEGG GENES v54long-chain acyl-CoA synthetase [EC:6.2.1.3] KEGG GENES v54galactokinase [EC:2.7.1.6] KEGG GENES v54Unknown KEGG GENES v54isocitrate dehydrogenase [EC:1.1.1.42] KEGG GENES v54aconitate hydratase 1 [EC:4.2.1.3] KEGG GENES v54sortase A KEGG GENES v54nitrogen regulatory protein P-II 1 KEGG GENES v54ABC.CD.P KEGG GENES v54CarD family transcriptional regulator KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54putative endopeptidase [EC:3.4.24.-] KEGG GENES v54Unknown KEGG GENES v54two-component system, NarL family, nitrate/nitrite response KEGG GENES v54DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37] KEGG GENES v54undecaprenyl-diphosphatase [EC:3.6.1.27] KEGG GENES v54tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33] KEGG GENES v54cobalt/nickel transport system permease protein KEGG GENES v54ammonium transporter, Amt family KEGG GENES v54Unknown KEGG GENES v54amino acid transporter, AAT family KEGG GENES v54beta-fructofuranosidase [EC:3.2.1.26] KEGG GENES v54O-sialoglycoprotein endopeptidase [EC:3.4.24.57] KEGG GENES v54Unknown KEGG GENES v54large conductance mechanosensitive channel, MscL family KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54aminoglycoside 3'-phosphotransferase [EC:2.7.1.95] KEGG GENES v54Unknown KEGG GENES v54putative biotin biosynthesis protein BioY KEGG GENES v54UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12] KEGG GENES v54putative MFS transporter, AGZA family, xanthine/uracil permease KEGG GENES v54two-component system, NarL family, response regulator KEGG GENES v54

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DeoR family transcriptional regulator, fructose operon KEGG GENES v54aminoglycoside 3'-phosphotransferase [EC:2.7.1.95] KEGG GENES v54Unknown KEGG GENES v54CTP synthase [EC:6.3.4.2] KEGG GENES v54alpha-glucosidase [EC:3.2.1.20] KEGG GENES v54alpha-glucosidase [EC:3.2.1.20] KEGG GENES v54non-specific protein-tyrosine kinase [EC:2.7.10.2] KEGG GENES v54sulfonate/nitrate/taurine transport system permease protein KEGG GENES v54UDPglucose 6-dehydrogenase [EC:1.1.1.22] KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54holo-[acyl-carrier protein] synthase [EC:2.7.8.7] KEGG GENES v54Unknown KEGG GENES v54biotin carboxylase [EC:6.3.4.14]|acetyl/propionyl carboxylase subunit KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54propionyl-CoA carboxylase beta chain [EC:6.4.1.3] KEGG GENES v54N-acetylglucosamine repressor KEGG GENES v54fatty acid synthase, bacteria type [EC:2.3.1.-] KEGG GENES v54Unknown KEGG GENES v54Unknown KEGG GENES v54oligo-1,6-glucosidase [EC:3.2.1.10] KEGG GENES v54ABC.CD.A KEGG GENES v54Unknown KEGG GENES v54putative acetyltransferase [EC:2.3.1.-] KEGG GENES v54large subunit ribosomal protein L31 KEGG GENES v54Unknown KEGG GENES v54cystathionine gamma-synthase [EC:2.5.1.48] KEGG GENES v54long-chain acyl-CoA synthetase [EC:6.2.1.3] KEGG GENES v54Unknown KEGG GENES v54polysaccharide transporter, PST family KEGG GENES v54Unknown KEGG GENES v54alpha-galactosidase [EC:3.2.1.22] KEGG GENES v54cystathionine beta-synthase [EC:4.2.1.22] KEGG GENES v54rhamnosyltransferase [EC:2.4.1.-] KEGG GENES v54transposase KEGG GENES v54transposase KEGG GENES v54multiple sugar transport system substrate-binding protein KEGG GENES v54transposase KEGG GENES v54multiple sugar transport system permease protein KEGG GENES v54

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Unknown KEGG GENES v54multiple sugar transport system permease protein KEGG GENES v54transposase KEGG GENES v54transposase KEGG GENES v54

d35 d36745.4 519.1

1898.5 1596.51672.0 3225.26743.8 8382.1

11330.1 6721.2972.8 545.7

14559.8 10063.41015.8 1381.82387.8 1974.49797.7 6901.6991.0 824.165.9 0.0

2819.8 1489.71574.5 959.0511.5 593.0

11308.5 10665.11401.7 1296.6258.7 53.611.6 117.4

1052.3 957.90.0 0.0

1896.7 2714.81284.0 2072.91711.1 1315.8677.6 199.9321.7 245.4764.9 632.4

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372.7 118.61218.9 932.31634.1 4316.2647.8 343.5

55134.3 46351.6917.4 2309.2

1242.1 1776.0491.5 466.4467.8 157.4

1477.8 1307.81434.2 1047.12392.1 3947.84626.4 4771.0655.9 520.5501.3 477.2137.2 0.0981.8 474.3

2343.3 2184.43030.0 2343.64242.1 3125.7920.0 480.0

3637.4 4038.52180.7 4331.62262.2 3437.61314.5 1556.8

19208.6 19606.51314.4 1603.3224.7 181.9

44909.6 73281.1739.6 0.0

187009.5 94257.713972.4 11926.71403.6 3350.43300.1 4085.2

30130.7 44578.87339.4 14935.7

0.0 157.812121.1 8208.4

632.2 644.8106.4 0.0

167065.8 174938.0

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2152.0 1956.465.9 11.287.8 79.523.5 4.3

409.2 92.70.0 423.7

307.6 683.561.8 59.7

1137.6 0.0409.7 274.1418.8 54.442.8 0.080.9 154.359.2 291.870.2 101.80.0 12.3

202.3 251.3101.6 0.0331.2 631.519.7 797.817.2 399.342.1 182.90.0 400.1

115.0 115.4150.6 454.6400.2 93.815.5 11.20.0 54.1

54.8 32.7111.6 46.283.4 644.9

293.8 71.0118.3 96.4403.9 520.3125.5 121.329.0 345.230.4 29.376.9 10.10.0 96.00.0 205.4

104.4 705.8

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285.4 24.393.4 35.314.0 40.40.0 0.0

86.7 97.7107.2 399.611.3 131.20.0 57.5

43.8 148.1564.5 597.8128.5 126.2

0.0 56.031.1 0.0

154.3 10.6217.0 0.0175.0 54.424.1 21.0

234.1 746.4256.0 313.9356.0 84.4

7.1 41.0316.5 122.3898.9 1377.282.0 237.528.5 339.3

199.1 108.20.0 150.50.0 250.30.0 730.6

222.8 256.166.5 443.1

438.0 0.0225.9 394.7

1407.4 2118.11148.2 810.73418.3 3715.5276.9 722.217.9 168.6

456.7 1229.32967.2 1856.91461.2 2808.2

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117.7 75.8462.4 35.316.9 293.20.0 49.2

90.1 248.029.8 5.6

1250.4 975.762.2 541.00.0 107.7

114.6 0.0122.6 158.055.0 0.00.0 0.00.0 29.7

10.1 43.930.6 738.8

133.1 233.81185.4 655.7119.4 79.3

0.0 0.055.0 0.00.0 88.90.0 0.0

328.0 198.07.7 44.7

93.9 149.6303.1 78.9124.3 0.088.2 55.9

116.8 0.031.7 137.913.8 30.054.5 263.5

490.0 96.88.7 12.69.4 27.2

15.5 11.2286.0 563.8186.3 861.778.0 10.398.9 230.8

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31.0 62.934.1 0.04.9 21.50.0 167.1

107.0 94.877.9 43.4

610.4 428.1898.7 0.0511.6 617.9529.2 265.5928.5 152.9295.9 376.9145.3 49.619.4 196.4

275.8 639.60.0 21.3

180.7 137.20.0 0.06.1 35.50.0 132.1

209.6 178.121.4 51.6

174.3 0.0100.7 20.9386.8 514.928.6 0.00.0 0.0

339.0 27.3255.5 88.2

0.0 97.030.6 44.4

320.7 199.20.0 56.50.0 0.0

1008.6 1320.358.2 50.6

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Log_1 Log_2 Stat_1 Stat_2106.0156 302.6844921 26625.17746 84307.0294658.9911 66.28550282 1151.943514 1860.510474

6.060619 15.1703107 107.5829659 221.2566367428.8915 430.4988895 3453.306934 7750.836087231.6643 206.5659495 2173.357712 3033.4481442143.339 2112.299909 12842.49315 28568.5304345.0819 67.87877772 256.7671918 592.1069602

278.7317 257.7059215 1827.675377 2137.9419151663.66 1509.772169 10203.65783 12856.63803

41.06937 41.60975638 231.311465 347.3158944763.3668 621.8991305 4854.901376 4818.8044967.21403 8.33418944 33.51555483 73.9639632

186.7912 192.4773064 1120.921566 1425.4047991105.97 1095.683647 5296.86391 9253.310696

1789.292 1424.110165 9754.197647 11472.972784.497225 3.618316689 23.77889377 25.17181362945.5255 1288.309216 4309.329089 9010.05334256.65998 67.79565042 316.7507393 408.56132443185.556 3452.840709 11961.7468 25313.7347258.98508 64.33117257 278.1244177 413.7844095367.1797 283.3134883 1434.433946 2175.55811838.10933 48.53242846 178.0869765 300.145038152.6139 130.4876495 819.2418177 706.4474466365.631 272.8706695 1666.835025 1756.783373

78.51346 104.329009 337.744926 637.4551461120.7779 93.96390055 353.8595532 738.68340759.357056 9.759004028 38.23908856 56.34334381138.8481 162.0861527 826.8303165 659.352315917.60305 13.43357421 73.13814474 79.86416414793.8042 763.923822 3682.75091 3976.407025

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166.4776 274.9715563 746.2516263 1401.649448898.6658 880.3942168 4300.798945 4216.367394177.2782 224.6688652 663.8513785 1247.00656310409.33 13221.37701 42240.16475 68145.486253789.869 3751.849199 13551.56416 20201.95827367.9258 277.0707287 1360.130647 1416.39379323.8042 265.4724191 1212.933507 1305.964083194.8603 157.5900669 870.7959914 633.2209773849.8829 768.8220406 2878.471149 4010.8501436.829851 5.128731963 34.37492803 16.255816092518.161 1967.169039 7843.522429 10902.38044331.181 326.6568034 1481.235797 1253.112643

490.6487 478.1955141 2074.551344 1792.916361364.398 1611.610215 4917.518056 6671.49970420126.42 17495.43585 54700.74425 87756.58883545.8076 439.9255804 1830.245814 1901.8844321931.364 1196.464822 5771.369495 5706.46498143.2328 139.5397438 665.443153 357.5981541884.2655 844.2778227 2749.43439 3495.794717232.5736 242.1768803 659.4171835 1045.6901173.983151 3.625531023 17.15942574 9.8118302655.132258 3.211633695 17.88291053 11.275710581096.853 1002.949421 3429.473035 3664.028226349.4822 343.6895539 1072.35806 1194.861466342.1374 281.3038762 991.0613242 1027.39096649.53638 44.28368459 120.5496945 175.5144436708.2866 718.5081502 1839.839898 2609.797383317.9917 312.0661349 832.6859562 1076.9348327.720701 4.831414168 20.92386923 16.9625907390.0281 516.146855 1113.725164 1576.2022395.027847 7.690946631 22.20528069 15.27392116212.7519 299.598636 542.7023904 942.558723227.36618 38.05565954 94.17788501 93.526613196.26882 78.27691739 242.14383 254.1655222134.9331 177.8991713 401.173754 487.2973175102.8072 87.99415326 235.0324026 298.982569661.74806 68.69392508 177.4996284 181.474019652.15522 54.78418233 125.4805065 167.332596419.74581 11.50424923 42.1778258 43.3820858835.51522 35.37139556 99.92936824 94.14636021119.5062 99.0096439 269.1345076 315.5631407

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15.30829 19.15905618 50.3770497 39.2381767689.84626 100.4643494 216.9405219 276.7732591138.9521 154.304091 322.7778388 433.9483637502.5455 412.0662503 1170.110865 1189.759956178.5936 165.5444143 422.5337957 461.2024058555.4303 541.7096745 1330.581836 1472.9337274.16194 0 10.74216501 10.15988505

58.17149 57.66875911 161.206559 118.6114029623.8837 679.0582483 1446.722241 1659.7514851986.975 1892.020099 3423.863977 5806.262416360.5587 439.7249866 822.8756356 1066.526527219.784 188.609146 502.4201562 456.8279242

844.9633 780.8609926 2051.061194 1764.144698533.8594 535.0868124 1032.99943 1454.533149109.4647 105.4685422 292.6241427 207.4127618.855192 10.34385214 24.68412385 19.88743457113.1881 111.7597525 324.7953058 195.327935722.32102 21.72786819 57.61161122 43.5910152144.22619 63.01844567 132.8535734 111.8547648420.1319 383.7324634 961.3289225 861.590147669.51049 95.11531441 193.7626423 177.8298044153.2108 129.6191417 336.0171307 301.7146328425.5159 458.105907 787.905959 1186.738827108.6337 87.69733238 172.6029225 256.2357451243.0925 279.1976652 531.9792701 603.55484139.24334 54.02642141 82.42386057 119.98768127.713249 6.435667521 16.59021623 13.80802911116.1422 87.07309315 247.4513438 188.73716454.234725 6.183288403 12.02302729 10.33756191530.054 1209.180086 2823.264501 2975.47209469.47607 61.89848921 120.3578382 156.95270779.7634 74.15774313 179.2860723 144.1994363

257.7237 258.2293596 487.9394146 588.045964526.7895 28.73858428 65.19382902 50.44908441

3.462273 3.370267249 6.851155499 7.3249777860 14.19448323 28.85486659 29.42658679

7701.196 8072.466649 3470.963127 4356.558711830.2901 990.5473488 530.5307647 369.7023258147.711 167.8202692 88.59356451 67.0921864

376.9881 297.6247877 198.5485517 134.27833062690.961 1910.452656 1299.636702 967.8462809

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47.85974 43.37496363 25.55756731 19.33777378373.5785 374.6249777 206.1893669 158.857187442.2976 590.0493048 283.6488048 218.9497523872.4155 812.9250355 432.5042174 387.741187440.3775 445.2528241 251.8771125 178.5221619694.6322 902.2755165 404.2735258 366.8003642102.5655 141.7770158 66.37917136 51.57017517442.5059 527.787118 274.6106932 193.28401685615.553 4558.498591 2418.416553 2486.183637164.9084 151.4008707 91.68120264 60.593658949565.889 8908.60742 5118.162361 3766.347543728.2851 705.6367616 391.2374069 290.410026841.91045 49.53888828 25.24033177 18.18832569693.9408 711.108314 314.4191369 346.198950128.06106 28.09580881 12.7025666 13.7002015626.33544 37.66865284 13.10908272 16.53133839139.6127 119.6649818 69.44871101 50.39922651037.972 943.9866498 487.4276528 428.5413428499.4328 602.6604729 298.3549701 210.4079421139.1311 198.1471553 88.66155788 66.9908271736.4904 711.3721106 337.0632478 328.6905392283.1345 273.0668924 151.3229886 102.016698120.97356 19.68706167 10.82674899 7.679913112303.045 398.5823418 192.9773952 126.0296475

865.2861 825.8257459 442.889035 323.5841996179.1711 171.3416192 98.80218834 59.37753182215.6642 219.4038508 116.6989744 79.43182861254.0622 256.0503985 127.352896 99.88513499514.9503 528.7590845 281.2494111 181.077445217.674 227.6577941 122.4190985 73.74896692

6.703797 6.525651687 2.883802687 0222.6684 173.4195907 106.3460257 65.0658746176.58908 85.72591479 44.47800825 25.73174979771.4713 728.7962192 386.9711352 261.6143989414.451 489.0342615 235.7912481 154.7196195

880.0661 967.3155332 454.6826188 338.4698002158.6467 132.7688555 65.12914663 59.0820523837.44576 44.26154966 17.07470652 17.67267728177.9194 204.0587621 97.01171698 65.35843581161.5341 160.3399056 78.92863023 57.109516991927.898 2322.335934 1032.213429 757.9959187

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212.8847 151.6482967 90.02163499 61.995993072097.471 1940.972754 920.3243396 763.378852455.60029 41.80580463 24.69655023 15.78234572302.9593 275.929245 141.6804466 96.65620376703.3859 694.773492 295.9177478 278.671132910349.19 9903.536292 3812.200869 4510.231706102.6513 111.9172042 54.49184062 32.55038263227.7747 221.3369681 117.4823509 63.999895781226.532 1106.904787 600.8929876 341.801918377.20701 48.31414168 22.41843132 28.2709845233.9453 268.0354815 129.0980904 72.67876045991.264 1088.391863 416.7371412 414.1892866

253.6477 218.4793907 120.4441212 68.18296262451.3442 477.7749694 230.9242997 139.6763917842.9035 608.7763143 354.713141 223.2506074152.2934 200.0703773 74.91576243 65.31484849490.8498 533.4902275 252.6794097 151.355837421.58543 33.31874763 10.02834205 11.59247825551.9451 539.7976619 274.8886565 152.9548324436.9992 329.3859887 182.5118328 115.4321794986.0103 1055.181321 440.4702409 347.0836408134.0504 118.1865495 63.0347091 34.18093358108.4896 173.5878511 62.037592 46.40121704274.1602 334.9937609 133.1399651 98.9622364733.24663 48.95265457 16.65745411 14.3223049216.6667 17.06659954 8.212440143 4.438448078

1742.627 1720.050458 671.3782178 623.17540671513.809 1960.173748 672.5529397 621.961659360.7379 420.1683973 141.6895788 148.7098248899.5761 701.3770842 366.0118572 227.6884888175.3346 177.6713597 85.81679087 44.68639485820.9188 822.5444797 349.9389202 256.97085471120.266 1107.559193 502.7711247 317.4889594485.4812 444.3115647 197.4791013 144.0457533149.3346 116.9710799 45.62347427 52.0781293491.12459 90.65258689 37.9933415 27.37821657199.4316 197.4561806 92.54788315 50.01789565188.8166 188.2120019 89.27810591 46.06507474961.6549 883.6346627 405.8847187 255.92246964.92408 66.98096915 25.13581694 21.84576075849.3424 989.0781755 385.2162171 264.6380883

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978.7764 898.5426795 403.4208912 256.6200047663.1047 580.9741609 242.6039513 193.151972140.6486 125.9002281 57.41105972 35.6059596269.98518 59.01974479 29.53731975 15.39793134589.095 515.8312955 226.4315068 158.2905242

1535.421 1212.768256 491.9170735 461.8893951440.596 1587.707759 591.690951 445.1056534390.4296 370.8218218 117.3965176 141.5126847366.8349 331.028156 134.6049813 101.9838567148.6781 193.9402574 69.72273138 46.00702666209.5398 314.4767482 109.9997697 66.3237296445.47546 35.39818126 17.39143767 9.747397529595.4502 499.54163 242.8320604 120.501829334.8768 63.99532948 18.76660518 13.85315885

240.1749 290.1976755 106.3397054 68.2978172380.63216 71.91645724 33.72905255 16.28975307415.2255 341.1256184 165.8749094 82.11356791537.8064 496.8736858 226.9817605 111.0015865452.2383 295.9805595 128.5044038 115.461871339.81527 46.09342441 17.72698082 10.20544508500.4418 431.8625437 193.7495943 107.879506877.01005 90.71226601 21.0458743 33.17513487375.6845 361.8427248 161.5621617 74.776754422.2406 528.4543745 190.4272999 113.890035311.12779 10.99497288 3.627960742 3.431306826694.7666 589.3462532 273.0351426 133.297691985.92393 71.69195217 28.8305848 20.97524656415.8783 580.1972589 151.2323003 159.4755156202.4235 228.4645961 88.75914252 43.67234173106.8209 96.07657212 37.57129165 24.39698336585.3454 550.1737484 235.8692307 109.5790651400.1607 335.4823661 143.922709 79.87286797511.5937 591.3005942 179.667445 154.778299318.87196 16.87082883 5.566789964 5.265041648232.2989 161.4642496 70.01741266 49.09570442972.1917 1298.542582 395.1155695 286.944769873.86648 62.28893151 27.27029781 13.57479423399.7828 496.1038521 162.41085 106.254712658.7314 71.3432559 18.72564173 20.24070486

249.9261 245.6171699 100.0076621 48.31703522958.5424 887.8266859 334.2337293 213.7442946

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14.95664 22.97326339 5.264154369 5.974572528592.4056 637.5882632 211.8848023 149.23372151175.449 1166.968292 416.4726831 270.1620907808.2855 758.3420605 304.1032296 153.567395213.8934 211.9275274 76.34080628 46.5034638485.89594 141.1654237 35.83054387 29.65230296245.3851 214.2304625 88.76640707 42.98440572415.7387 422.0773547 167.9621946 71.25365654540.6726 481.3359936 176.940419 114.304054253.54626 52.28177008 21.1718975 8.899676987.17373 95.59062736 36.48429861 15.36913521

622.56 624.9386174 238.6975111 114.6431876232.2035 181.6336341 78.94996043 38.152795514455.709 6008.055286 1585.767563 1343.223476687.5857 574.6521579 228.7828619 123.8146426289.9536 370.0667144 123.0394103 61.1842524324.45028 26.4006001 8.538049078 5.6175606352020.178 2391.007158 548.4539079 679.4565825271.2284 285.5124538 106.0807418 48.69980964181.9355 158.3328976 52.97458848 40.52552147580.4559 564.9501002 197.8504499 116.5613702236.8224 232.2267268 85.70101213 40.527790791075.442 957.5451697 336.4354658 205.5446654175.9883 158.1550107 59.42610508 29.07150418111.9615 113.4036334 25.20156014 34.32313074579.2201 536.8600333 152.1513208 142.3363646142.9433 102.2342367 36.08314433 28.3287196612200.94 13697.27437 4436.585922 2356.18822102.7206 64.25701248 29.67456719 14.08658857344.8996 336.1905517 119.9550029 53.009728214763.967 4520.789589 1608.285505 732.3046906837.959 801.1938057 257.4156547 149.6988243

191.2684 204.0485173 62.84764266 35.1477104612.05268 12.57042148 3.110853215 2.9422291566109.378 6410.479725 1918.975106 1133.603142344.6688 444.2223383 119.7738456 72.38734489347.8103 467.6179172 128.1532005 69.71660438102.6264 109.2627346 34.1591858 17.00399172220.6457 368.6403603 79.78428999 62.462682341615.577 1556.444376 418.4913918 341.8748951682.998 1335.128856 505.3627479 213.5092262

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87.36566 83.22477538 28.34627286 11.84234831210.6556 187.9505187 61.80478255 31.93913819320.7242 219.9772451 89.79573036 37.15615106560.1704 461.0849608 171.5497353 68.21911477791.804 1115.371622 287.3128313 160.131919791.7232 43.62247916 12.78406414 18.80838225

671.5038 671.7647878 198.0971236 114.24680491094.201 797.0061605 226.1208791 211.735850599.30244 197.3886973 33.92262634 34.22277071171.0535 258.2307573 53.08272244 45.33106135257.2518 255.6765045 82.78511752 34.69192318219.8953 211.8133239 59.24896942 39.34929212241.6716 259.7242468 75.25871817 38.4753043590.28717 84.00283037 24.7984899 14.47179329472.3895 482.7453992 133.1964424 81.4002117104.5893 134.4770906 27.38341724 25.89909682201.3681 206.2753474 47.34271525 39.9094886447.3536 413.8392962 129.3395898 52.49355315267.7962 289.704128 75.23791728 42.12900586188.3187 222.7310103 51.11140902 35.07085686118.6914 264.6461194 48.40596614 30.38075946689.684 841.8752805 196.4835232 115.091911

108.8822 97.67085168 28.22362512 13.68910828248.2495 227.9759896 66.0069977 29.94908705358.8076 317.8197063 91.86473904 43.56869085185.8976 252.7249191 61.47880507 26.27767347248.1827 216.7308058 64.77687442 28.1821937265.28534 77.88312201 19.14498495 8.951888709104.9218 141.212711 29.80249105 17.76169929822.1658 665.2730167 196.1858557 88.76531153572.683 595.6167386 114.1247611 109.2390841495.652 776.6365544 143.5436555 98.60670857

689.0028 840.1830426 181.8506399 105.386943426.6596 25.82220575 4.667092056 5.0932060851652.04 1680.500494 402.9192384 213.1910307

13.20269 14.45832121 2.555756731 0123.0925 175.5230806 28.12494111 26.60042632434.7869 310.0261192 97.01171698 31.841289241017.637 811.1164885 197.4615897 117.57909061691.686 1927.505506 424.3848718 194.5100519203.0522 216.2469608 50.78114368 20.31977011

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1009.466 852.2803624 189.0818826 124.210148217.91687 19.93229163 3.082953186 017.37158 21.13743698 4.110045742 2.1203238371844.262 1920.408281 438.8158468 145.4823185594.6665 614.5720458 97.93170818 82.93610299594.6665 614.5720458 97.93170818 82.93610299437.0531 1032.929491 110.6574929 105.9202496436.5785 361.7345339 90.58398119 26.00930574393.423 564.746598 93.1458555 46.66866206

473.8209 552.9414148 109.0742909 40.6395402298.70206 220.5009762 28.70229416 17.7866328528.81343 49.41746943 8.263203853 3.126118478392.589 145.1227017 48.74056959 29.11489448

164.5292 351.5026582 39.78372685 34.24502219521.8786 326.4298318 77.59121961 41.29011984297.247 306.3116583 60.38030836 22.6167876

200.6853 144.6115063 23.54447125 0536.4846 312.3830663 75.03049894 36.67774568279.5849 244.5780573 39.996865 28.04095208735.841 342.8818187 94.5936725 41.6672868426.6596 29.01371432 3.590070812 3.395470723

72.67755 88.25252444 14.62169019 5.117383703572.6878 668.107775 70.15291434 71.2392369980.00984 65.23155483 9.912440626 6.02687311276.40632 280.5034633 18.81064023 20.0866218270.13779 54.86300649 9.257161946 3.5021506831405.113 1071.913044 121.7715611 79.7455128825.84969 28.13228503 2.610754027 1.6461585914895.811 3883.614063 474.5202831 180.9583612499.4505 305.3957613 49.58797188 8.98415669421.88438 13.69467748 1.21038479 033.69742 96.7292182 4.30883499 4.52808247650.57548 109.0126045 6.526885069 4.115396478933.2336 808.1638245 67.45035383 47.991968296493.988 5375.647608 477.6731903 181.222836850.44776 289.1046576 8.223666992 7.777902434114.5055 89.07177892 4.095300435 3.243900753114.5055 89.07177892 3.967322297 3.243900753578.2331 746.4333428 14.85497269 21.19787996113.613 90.18879612 3.327431604 2.033490024

758.8681 767.4207587 15.95300527 19.39920594

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2401.313 4132.368931 101.5622874 48.02854753762.5749 845.1809049 15.93998679 11.14309974113.5139 87.2928256 1.79169394 0.58099715113.5139 87.2928256 1.79169394 0.58099715

d42 In vitro (Log) In vitro (Stationary) Product (Unboosted) Product (Boosted)2973.6 234.3 334.0 601.6 372.11741.1 372.3 235.8 555.0 730.82078.1 1016.7 408.2 413.8 427.05970.1 62.2 1397.0 242.6 190.56271.4 680.5 1206.7 833.2 452.81116.9 497.6 343.5 340.5 339.1

16793.0 3224.3 2516.7 6776.7 7159.81576.8 618.1 475.9 498.0 294.11904.3 588.5 481.9 216.8 285.09473.7 55.2 372.7 127.7 522.72363.3 652.3 593.5 528.9 603.6356.7 51.5 49.3 111.4 167.8

1848.7 38.1 31.1 41.1 3.62710.2 30.3 35.3 33.8 14.7172.7 46.0 30.5 27.5 9.6

7457.5 101.2 93.4 25.4 28.11476.9 237.3 201.5 529.6 469.1266.9 15.9 16.1 72.9 64.3241.7 13.2 26.8 68.5 48.5

1567.9 41.2 126.7 463.3 642.5212.7 24.8 16.6 67.8 34.9

3922.7 228.8 315.2 658.4 287.01576.3 682.3 701.7 753.6 732.31612.2 545.2 383.0 379.0 243.6238.6 63.8 60.6 60.0 100.8393.0 97.3 92.1 50.1 129.2492.9 119.5 232.2 21.3 12.3

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611.9 42.7 220.3 26.9 78.52030.5 61.6 348.5 50.1 110.64527.3 90.0 441.4 78.0 12.31393.7 69.4 115.4 93.5 72.1

56387.1 3304.3 16579.3 6054.0 2857.91232.9 322.8 591.4 285.8 322.11296.5 399.3 444.3 74.0 191.4688.2 5.1 5.7 52.0 12.7614.1 23.1 9.2 49.4 17.6

1042.3 152.9 59.9 38.7 188.6386.7 69.5 52.2 32.2 22.0

4874.3 1894.3 1534.1 1889.5 2113.16127.1 1667.5 1293.2 1181.0 1221.4918.3 293.7 199.9 277.3 213.1448.8 65.2 71.8 203.6 153.1394.2 55.2 59.1 116.0 195.3730.5 166.4 125.1 111.8 261.9

3871.3 356.8 247.5 149.9 82.45264.1 359.5 299.0 72.5 30.83918.6 396.1 278.1 176.3 77.3840.0 287.8 314.7 326.8 258.4

5540.9 2041.0 1944.6 1566.2 531.35270.6 47.2 139.6 189.8 74.84402.3 53.3 140.0 249.8 100.41006.2 9.5 44.5 41.8 66.1

14361.0 3691.9 2593.6 5024.7 4663.01250.2 409.0 383.8 340.4 226.2151.3 60.3 62.7 69.1 53.6

81450.5 1766.2 5940.5 16034.1 6674.9429.2 141.5 152.3 156.3 151.2

149024.1 193.4 46573.3 6931.7 21509.17317.3 271.4 349.0 253.3 137.82670.4 203.9 262.1 488.7 648.84035.5 1984.6 1809.8 1395.3 533.2

55229.5 8031.0 13401.5 21862.6 15592.113058.6 780.9 397.9 6521.5 3973.4

421.4 68.3 83.5 161.2 195.57236.3 394.3 435.1 381.5 391.3742.9 185.7 80.3 346.5 196.0411.7 161.9 164.3 135.0 81.1

145439.4 11260.1 12358.4 56139.3 64829.7

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2830.8 859.9 513.5 1042.2 913.222.5 289.6 100.5 143.5 186.493.4 344.6 637.2 454.7 299.020.4 170.2 67.6 78.2 139.839.6 225.9 423.8 302.8 578.9

122.8 674.4 254.0 494.5 285.347.6 501.2 217.7 343.9 273.831.9 405.4 282.9 609.6 676.5

293.4 2914.7 1656.5 2992.7 3988.5195.1 2626.8 1402.1 2984.9 3944.972.6 1352.3 816.4 573.5 172.149.7 213.3 158.2 285.3 219.036.3 155.8 126.6 88.2 153.4

201.7 1130.0 622.8 490.8 2274.1113.2 1074.2 798.8 744.6 679.239.3 304.1 135.9 275.3 103.9

127.8 710.4 425.4 659.8 521.178.6 232.9 170.3 400.8 661.4

263.0 2979.0 2481.4 1289.7 588.2258.6 866.5 3007.5 523.7 728.179.9 813.9 3270.1 305.8 782.465.1 811.9 895.2 2271.7 2821.554.6 347.4 501.7 285.0 453.7

102.7 1114.6 438.7 497.6 574.8223.3 816.5 1951.8 594.2 745.554.6 759.0 347.8 296.1 480.142.0 142.7 324.2 114.8 85.243.3 151.0 103.9 165.6 187.434.9 210.1 162.4 190.7 116.043.2 221.8 253.4 118.0 107.1

215.2 592.2 683.1 1399.4 1415.175.8 160.9 274.1 652.2 874.454.3 228.9 251.8 137.8 145.5

138.9 649.5 371.2 1328.1 1899.272.8 412.3 340.8 247.7 239.0

130.3 947.5 755.0 756.4 447.293.9 918.8 414.5 359.3 207.2

146.0 779.4 364.9 796.4 489.951.3 212.4 434.5 235.3 178.8

338.1 1913.8 1832.6 1712.8 1964.4107.7 874.0 1481.4 720.7 2022.0

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168.9 382.7 504.2 944.1 863.491.1 516.7 313.5 661.1 297.021.6 95.7 124.0 62.0 85.697.1 294.5 229.3 297.1 283.789.5 315.7 206.9 285.1 306.0

130.4 833.9 453.2 634.7 658.7166.3 797.9 413.1 602.7 570.776.8 752.5 159.0 1175.2 528.9

101.6 438.0 346.7 475.2 432.633.6 315.1 1003.6 321.3 68.686.6 313.6 305.6 269.9 474.352.3 196.4 138.3 343.0 1435.796.4 266.9 227.2 276.5 201.462.5 400.7 193.4 174.0 360.056.0 266.5 114.9 325.9 193.4

116.1 1113.7 977.2 758.5 457.822.4 252.5 115.5 99.9 162.3

115.9 497.6 640.1 415.7 350.5205.7 810.6 981.7 670.2 496.9255.4 982.6 787.2 1589.9 749.738.3 933.7 480.1 261.9 252.6

473.5 1986.8 1340.2 1811.2 1376.5874.4 4323.2 2854.9 2812.4 3209.9226.5 469.4 454.3 693.0 1195.566.1 786.1 252.0 224.7 200.996.3 370.8 485.7 368.3 725.596.5 462.1 229.5 983.8 980.0

147.7 641.6 631.4 430.4 330.065.0 154.0 431.0 828.9 1265.3

190.3 928.0 388.8 1000.6 635.5267.4 2028.0 866.0 1613.1 765.6149.1 346.9 1114.7 1244.4 430.597.7 423.2 439.6 412.9 256.0

942.4 4898.9 2918.8 3364.2 2000.2501.2 6191.5 6095.1 3398.2 2277.8

1653.1 7272.0 7906.3 11697.6 7264.31242.5 3228.4 3266.8 6555.0 3577.5

41.5 901.5 474.9 794.5 716.61565.1 8124.7 6178.5 4827.7 4360.71200.1 7210.1 3429.6 16565.2 5938.7835.7 7866.1 3777.2 9965.4 6473.1

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60.7 234.2 233.9 232.2 3721.575.3 321.4 157.3 252.1 166.965.2 309.8 190.0 149.7 182.38.8 66.7 65.0 50.3 121.9

97.6 485.3 494.0 399.9 314.96.0 561.3 76.3 53.6 119.2

409.3 2534.5 2569.4 5977.9 5363.2625.9 2517.3 1292.4 2578.1 2311.5103.5 295.4 330.9 1055.9 916.663.4 283.9 179.4 145.4 467.8

100.1 454.6 317.0 524.2 294.7184.3 1903.8 1138.7 596.3 429.0426.7 2762.1 1528.4 5803.0 5767.6

3.2 74.0 29.4 121.3 100.015.6 297.5 100.4 627.3 286.831.6 403.5 200.9 512.9 173.5

149.8 314.3 323.5 823.6 418.4483.1 1379.2 1298.5 2329.9 1129.288.6 345.2 242.9 265.1 418.896.0 700.9 490.7 367.3 311.163.8 284.7 187.0 203.4 154.535.6 294.7 135.6 295.1 243.445.0 114.8 146.6 206.6 167.9

634.4 2098.2 2996.6 7360.7 4866.135.8 315.4 917.2 2419.7 4019.487.2 598.9 601.5 555.6 392.9

120.3 612.4 489.6 759.1 412.585.5 478.0 369.0 204.4 332.051.2 420.6 261.7 272.5 246.455.6 252.8 114.5 372.4 621.549.1 355.5 99.6 156.4 421.437.4 354.6 158.5 654.0 433.128.1 111.5 98.6 161.4 217.5

224.0 586.0 601.6 922.8 530.753.8 467.0 216.6 489.0 336.936.3 236.7 173.8 241.7 362.865.9 264.3 200.9 343.7 412.8

230.2 485.1 1977.2 609.5 725.3138.6 1878.1 337.4 593.6 338.7153.6 456.1 310.2 419.6 437.529.7 227.5 158.4 487.6 139.4

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24.0 330.8 158.0 257.0 231.266.0 157.3 139.7 202.0 181.523.0 162.4 51.5 102.4 241.759.5 261.7 342.3 682.6 668.623.0 459.0 203.4 264.0 335.20.0 132.8 99.3 106.4 111.1

99.0 1773.7 1396.2 582.8 487.7107.9 1247.5 1155.8 458.6 461.4117.3 1547.4 1426.0 476.7 560.5110.3 1097.8 5935.0 1024.2 1065.5212.3 1101.4 6665.1 499.7 1234.062.5 495.6 207.0 132.7 180.139.7 212.3 99.4 607.2 566.70.0 469.5 77.1 429.7 486.9

298.8 1364.4 992.4 1436.8 1528.030.3 100.4 64.4 87.0 93.526.6 143.0 144.9 101.9 146.036.7 97.3 77.0 168.6 810.1

104.1 298.8 381.9 271.6 322.0250.0 747.6 1343.4 833.7 666.4117.5 790.4 1149.8 363.7 260.127.6 204.5 277.0 274.2 109.884.3 184.0 176.2 257.9 675.861.2 573.6 169.7 170.3 220.042.8 88.4 90.2 257.0 175.651.6 962.2 221.1 290.2 265.231.2 463.1 199.4 3288.9 1390.6

291.4 967.1 602.3 891.7 6310.456.5 545.3 267.9 432.2 223.00.0 17.8 1.7 33.0 30.8

94.8 207.6 197.5 272.0 564.4389.9 1773.7 1122.2 4067.4 2902.420.1 245.7 207.0 153.8 48.452.3 579.8 263.6 320.0 461.4

377.6 5492.8 2921.5 2118.5 821.899.1 577.5 359.3 413.4 270.2

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Table S8. Top-down function-level analysis of the impact of the FMP strain consortium on the model human gut microbiota's metatranscriptome.

A. Proportional representation of assignable normalized RNA-Seq counts binned by KEGG category in fecal samples collected over time from singly- and multiply-treated animals.

RATIOS

Mouse Day Carbohydrate Metabolism1 Pre-treatment 14 0.1282 Pre-treatment 14 0.1253 Pre-treatment 14 0.1514 Pre-treatment 14 0.1315 Pre-treatment 14 0.1246 Pre-treatment 14 0.1197 Pre-treatment 14 0.1218 Pre-treatment 14 0.1249 Pre-treatment 14 0.110

10 Pre-treatment 14 0.1181 Single-treatment 15 0.1412 Single-treatment 15 0.1303 Single-treatment 15 0.1324 Single-treatment 15 0.1345 Single-treatment 15 0.1386 Multiple-treatment 15 0.1397 Multiple-treatment 15 0.1428 Multiple-treatment 15 0.1409 Multiple-treatment 15 0.113

10 Multiple-treatment 15 0.1156 Multiple-treatment 35 0.1407 Multiple-treatment 35 0.1448 Multiple-treatment 35 0.1379 Multiple-treatment 35 0.142

10 Multiple-treatment 35 0.1286 Multiple-treatment 36 0.1407 Multiple-treatment 36 0.1338 Multiple-treatment 36 0.1329 Multiple-treatment 36 0.135

10 Multiple-treatment 36 0.1291 Single-treatment 42 0.1552 Single-treatment 42 0.1273 Single-treatment 42 0.138

(normalized counts category x / normalized counts all categories)

Treatment group

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4 Single-treatment 42 0.1335 Single-treatment 42 0.1246 Multiple-treatment 42 0.1307 Multiple-treatment 42 0.1298 Multiple-treatment 42 0.1209 Multiple-treatment 42 0.137

10 Multiple-treatment 42 0.150

d14all-v-d15all 0.094* d14multi-v-d15multi 0.081* d14multi-v-d35multi 0.008* d14multi-v-d36multi 0.009* d14multi-v-d42multi 0.090

d14all-v-d42all 0.091

*

B. Proportional representation of assignable normalized RNA-Seq counts binned by KEGG pathway in fecal samples collected over time from singly- and multiply-treated animals.

RATIOS

Mouse Day

1 Pre-treatment 14 0.01322 Pre-treatment 14 0.01443 Pre-treatment 14 0.01774 Pre-treatment 14 0.01565 Pre-treatment 14 0.01486 Pre-treatment 14 0.01247 Pre-treatment 14 0.01488 Pre-treatment 14 0.01399 Pre-treatment 14 0.0138

10 Pre-treatment 14 0.01471 Single-treatment 15 0.01612 Single-treatment 15 0.01613 Single-treatment 15 0.0156

(normalized counts pathway x / normalized counts all pathways)

Carbohydrate Metabolism

Treatment group Fructose and mannose metabolism

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4 Single-treatment 15 0.01615 Single-treatment 15 0.01706 Multiple-treatment 15 0.01717 Multiple-treatment 15 0.01778 Multiple-treatment 15 0.01739 Multiple-treatment 15 0.0139

10 Multiple-treatment 15 0.01386 Multiple-treatment 35 0.01677 Multiple-treatment 35 0.01758 Multiple-treatment 35 0.01619 Multiple-treatment 35 0.0180

10 Multiple-treatment 35 0.01606 Multiple-treatment 36 0.01927 Multiple-treatment 36 0.01678 Multiple-treatment 36 0.01669 Multiple-treatment 36 0.0184

10 Multiple-treatment 36 0.01651 Single-treatment 42 0.02022 Single-treatment 42 0.01543 Single-treatment 42 0.01604 Single-treatment 42 0.01635 Single-treatment 42 0.01716 Multiple-treatment 42 0.01577 Multiple-treatment 42 0.01478 Multiple-treatment 42 0.01519 Multiple-treatment 42 0.0179

10 Multiple-treatment 42 0.0168

d14all-v-d15all 0.0489* d14multi-v-d15multi 0.1273* d14multi-v-d35multi 0.0072* d14multi-v-d36multi 0.0200* d14multi-v-d42multi 0.0479

d14all-v-d42all 0.0304

*

C. Proportional representation of assignable normalized RNA-Seq counts binned by genes of interest in fecal samples collected over time from singly and multiply-treated animals.

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EC: 3.2.1.65 (levanase)Mouse Day Total BACCAC_02726

1 14 73.868 0.4302 14 30.611 0.3783 14 21.041 0.1604 14 56.678 0.2145 14 32.684 0.4376 14 73.413 0.3847 14 47.412 0.2018 14 66.058 0.3859 14 38.745 1.438

10 14 34.065 0.3901 15 62.096 0.2412 15 21.591 0.2023 15 41.281 0.2514 15 40.189 1.7925 15 47.426 0.1996 15 48.602 1.0357 15 36.741 0.1728 15 335.220 0.3839 15 25.184 0.293

10 15 33.564 0.3396 35 70.409 0.2227 35 100.227 0.1428 35 23.687 3.6689 35 40.229 0.240

10 35 48.655 0.3926 36 617.221 0.2067 36 156.302 0.2408 36 152.271 0.3149 36 418.801 1.587

10 36 39.817 0.4111 42 928.255 0.2632 42 184.829 0.3143 42 47.533 0.3294 42 369.707 0.2695 42 237.091 0.3926 42 97.702 0.2567 42 287.823 4.0788 42 160.666 0.5909 42 372.451 1.155

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10 42 48.610 0.169

Group Total BACCAC_02726d14 47.4575 0.442d15 69.1894 0.491d35 56.6414 0.933d36 276.8824 0.552d42 273.4667 0.782

EC: 3.1.1.11 (pectinesterase)Mouse Day Total BACCAC_01748

1 14 88.836 0.8792 14 166.569 0.7733 14 224.922 0.3264 14 220.992 0.4375 14 109.774 0.8926 14 245.139 0.7847 14 97.145 5.7428 14 132.078 0.7879 14 178.024 0.489

10 14 179.258 2.3911 15 272.397 0.4932 15 314.714 0.4123 15 408.777 0.5124 15 282.494 3.9955 15 378.365 0.4086 15 448.179 0.3027 15 388.887 0.3518 15 399.447 1.1759 15 307.640 2.396

10 15 295.372 1.3876 35 484.702 0.4537 35 577.585 0.2908 35 465.683 0.4419 35 667.282 0.490

10 35 452.068 0.8016 36 467.409 1.2647 36 598.775 0.4908 36 401.071 0.641

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9 36 313.933 0.54010 36 423.023 0.8391 42 277.889 3.2252 42 305.723 0.6423 42 146.489 0.6724 42 182.241 1.6485 42 261.803 0.8016 42 442.346 4.1907 42 189.643 3.4728 42 178.726 1.2079 42 233.801 0.943

10 42 421.989 0.345

Group Total BACCAC_01748d14 164.274 1.350d15 349.627 1.143d35 529.464 0.495d36 440.842 0.755d42 264.065 1.715

EC: 2.4.1.20 (cellobiose phosphorylase)Mouse Day Total BACUNI00385

1 14 11.191 3.2532 14 6.04 2.2893 14 18.131 8.5724 14 18.489 7.7675 14 8.915 7.5996 14 1.445 0.297 14 7.642 4.4028 14 2.034 0.8749 14 6.018 3.262

10 14 13.577 5.91 15 18.422 17.6952 15 30.332 6.2543 15 19.412 4.9244 15 16.137 9.6095 15 42.791 0.1516 15 16.925 3.6917 15 13.641 6.493

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8 15 9.995 2.3189 15 12.948 7.313

10 15 13.07 5.6466 35 17.101 9.2347 35 18.372 7.2038 35 14.294 8.6479 35 11.018 3.445

10 35 81.481 9.7896 36 10.817 7.4877 36 11.801 11.0788 36 3.846 0.2379 36 6.005 4.8

10 36 96.165 4.9691 42 13.974 0.7962 42 20.611 1.6633 42 26.68 2.7334 42 11.903 5.2845 42 14.401 5.0436 42 15.395 10.4687 42 8.474 7.4528 42 5.632 2.0099 42 13.28 3.668

10 42 57.787 1.021

Group Total BACUNI00385d14 93.482 4.4208d15 193.673 6.4094d35 142.266 7.6636d36 128.634 5.7142d42 188.137 4.0137

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Table S8. Top-down function-level analysis of the impact of the FMP strain consortium on the model human gut microbiota's metatranscriptome.

A. Proportional representation of assignable normalized RNA-Seq counts binned by KEGG category in fecal samples collected over time from singly- and multiply-treated animals.

Amino Acid Metabolism Nucleotide Metabolism Lipid Metabolism0.074 0.030 0.0250.075 0.031 0.0270.069 0.031 0.0210.064 0.030 0.0250.072 0.031 0.0250.068 0.028 0.026 *0.068 0.027 0.031 *0.069 0.027 0.026 *0.080 0.029 0.033 *0.075 0.030 0.030 *0.066 0.033 0.0220.067 0.031 0.0260.065 0.030 0.0240.060 0.032 0.0210.066 0.030 0.0190.063 0.032 0.020 *0.070 0.031 0.024 *0.066 0.031 0.020 *0.067 0.030 0.029 *0.071 0.030 0.029 *0.063 0.031 0.018 *0.062 0.031 0.019 *0.068 0.032 0.021 *0.061 0.031 0.017 *0.063 0.033 0.023 *0.060 0.031 0.018 *0.058 0.030 0.022 *0.064 0.029 0.021 *0.064 0.030 0.023 *0.060 0.033 0.023 *0.063 0.030 0.0180.061 0.029 0.0210.061 0.027 0.022

/ normalized counts all categories)

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0.065 0.029 0.0230.065 0.031 0.0250.066 0.031 0.023 *0.072 0.028 0.027 *0.064 0.029 0.026 *0.061 0.030 0.019 *0.069 0.031 0.020 *

0.002 0.031 0.0070.117 0.043 0.0140.051 0.001 0.0080.007 0.008 0.0010.200 0.031 0.0630.012 0.861 0.016

: data depicted in Figure 4A

B. Proportional representation of assignable normalized RNA-Seq counts binned by KEGG pathway in fecal samples collected over time from singly- and multiply-treated animals.

Amino Acid Metabolism

Purine metabolism

0.0067 0.0139 0.0160 0.01440.0069 0.0143 0.0165 0.01530.0080 0.0136 0.0121 0.01750.0065 0.0147 0.0126 0.01660.0060 0.0140 0.0160 0.01490.0064 0.0138 0.0149 0.01480.0062 0.0132 0.0158 0.01350.0065 0.0145 0.0145 0.01420.0052 0.0112 0.0307 0.01460.0058 0.0120 0.0241 0.01520.0082 0.0147 0.0127 0.01820.0086 0.0146 0.0132 0.01660.0086 0.0155 0.0118 0.0159

: p-value < 0.05 by paired, two-tailed t-test

/ normalized counts all pathways)

Carbohydrate Metabolism

Carbohydrate Metabolism Nucleotide Metabolism

Pentose and glucuronate

interconversionsStarch and sucrose

metabolismAlanine, aspartate and glutamate metabolism

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0.0081 0.0141 0.0108 0.01840.0080 0.0136 0.0137 0.01590.0082 0.0139 0.0118 0.01840.0096 0.0142 0.0123 0.01720.0089 0.0153 0.0120 0.01710.0063 0.0118 0.0215 0.01570.0066 0.0122 0.0214 0.01590.0088 0.0142 0.0117 0.01770.0095 0.0129 0.0117 0.01790.0099 0.0150 0.0114 0.01770.0102 0.0146 0.0105 0.01830.0079 0.0141 0.0114 0.01810.0095 0.0166 0.0106 0.01740.0100 0.0148 0.0107 0.01700.0087 0.0157 0.0118 0.01650.0090 0.0175 0.0122 0.01630.0077 0.0146 0.0113 0.01890.0075 0.0157 0.0111 0.01690.0085 0.0148 0.0115 0.01610.0078 0.0133 0.0116 0.01390.0068 0.0164 0.0124 0.01520.0076 0.0158 0.0133 0.01600.0078 0.0150 0.0134 0.01660.0069 0.0153 0.0154 0.01340.0069 0.0150 0.0133 0.01460.0080 0.0162 0.0117 0.01670.0080 0.0132 0.0122 0.0169

0.0001 0.0675 0.0018 0.00810.0161 0.0292 0.0299 0.01970.0033 0.1387 0.0648 0.00030.0019 0.0330 0.0450 0.00210.0311 0.0669 0.1425 0.05460.0038 0.0081 0.0383 0.3941

: data depicted in Figure 4B

C. Proportional representation of assignable normalized RNA-Seq counts binned by genes of interest in fecal samples collected over time from singly and multiply-treated animals.

: p-value < 0.05 by paired, two-tailed t-test

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BACCAC_02731 BACOVA_04501 BACOVA_04507 BACUNI_0115627.012 3.064 0.430 0.54511.687 0.385 0.378 0.4790.822 0.162 0.160 4.652

29.961 3.485 0.214 0.2718.997 1.334 0.437 0.553

28.424 0.390 0.384 0.48624.387 1.839 0.201 0.25432.522 3.921 0.385 0.4888.882 1.219 1.438 2.4295.221 1.588 0.390 0.494

10.928 7.366 0.241 5.50113.084 0.205 0.202 0.25513.407 0.255 0.251 0.31712.243 0.331 0.163 1.03215.812 0.203 0.199 0.2536.243 2.409 0.148 1.8735.481 1.049 1.030 0.218

11.047 0.195 0.191 0.2432.112 2.387 0.293 0.3712.795 1.036 0.339 0.8608.457 0.226 0.222 0.2812.342 0.145 0.142 3.4224.220 1.098 0.216 0.2740.740 0.244 0.240 0.3047.269 5.590 0.785 0.4970.637 1.469 1.444 1.5680.247 0.244 0.240 0.3040.323 0.319 0.314 10.331

11.708 4.037 0.264 0.3353.383 2.508 2.054 0.5206.228 3.748 0.789 0.3333.882 3.518 0.314 0.3985.751 0.335 0.329 0.416

18.814 4.650 2.150 0.34017.771 1.198 0.392 0.49711.613 3.914 0.256 0.3259.096 1.383 0.340 0.431

19.143 1.502 0.295 0.3745.945 1.175 0.231 0.292

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1.564 0.515 3.037 0.214

BACCAC_02731 BACOVA_04501 BACOVA_04507 BACUNI_0115617.792 1.739 0.442 1.0659.315 1.544 0.306 1.0924.606 1.461 0.321 0.9563.260 1.715 0.863 2.6129.981 2.194 0.813 0.362

BACCAC_01750 BACOVA_03088 BACOVA_03576 BACOVA_035810.465 0.739 1.498 1.8600.409 0.650 4.833 2.7280.173 0.274 44.120 43.5000.231 3.309 11.926 32.3920.472 0.750 1.522 0.6300.415 0.659 21.818 9.3980.217 2.760 4.895 8.1040.416 0.662 9.393 14.4392.331 2.471 11.408 8.6371.687 1.341 17.666 7.8730.261 0.415 21.849 13.9110.218 0.346 50.126 47.1130.271 0.431 66.303 55.2410.352 0.559 14.944 22.5460.216 0.343 8.338 57.5091.599 4.067 53.581 73.5611.300 0.295 53.243 46.2980.207 1.646 57.624 88.6710.317 2.518 45.260 26.1960.734 2.916 27.582 21.0360.240 0.381 135.854 48.6490.154 5.863 93.600 117.8500.233 0.371 60.876 83.0470.259 10.302 118.893 144.8472.120 7.415 51.017 93.3140.223 6.026 95.322 92.1810.259 17.334 154.217 122.2220.339 0.539 65.557 75.063

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0.286 3.181 38.385 53.3770.444 9.176 55.322 74.6070.284 4.520 32.985 39.4360.340 4.859 41.593 53.9060.355 5.647 34.342 14.6860.930 6.004 29.333 17.0471.272 8.763 23.687 41.2850.859 12.335 63.403 83.5230.367 7.591 11.443 8.8180.957 3.550 15.765 14.0410.499 3.175 30.304 39.6220.730 4.930 53.495 56.686

BACCAC_01750 BACOVA_03088 BACOVA_03576 BACOVA_035810.682 1.362 12.908 12.9560.548 1.354 39.885 45.2080.601 4.866 92.048 97.5410.310 7.251 81.761 83.4900.659 6.137 33.635 36.905

EUBREC1072 EUBREC2816 EUBREC2817 RUMOBE035550.33 0.299 0.335 6.9742.61 0.263 0.294 0.584

2.202 2.888 4.346 0.1230.164 0.149 0.166 10.2430.335 0.304 0.34 0.3370.294 0.267 0.298 0.2960.154 0.14 0.156 2.790.295 0.268 0.3 0.2970.183 0.167 0.186 2.221.794 1.357 1.213 3.3130.185 0.168 0.188 0.186

16.078 3.93 2.824 1.2460.192 0.174 0.974 13.1480.125 0.113 0.127 6.1630.153 0.139 0.155 42.1930.113 0.103 0.115 12.9030.132 0.12 0.134 6.762

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0.147 0.133 0.149 7.2480.225 0.204 0.228 4.978

1.3 1.653 2.375 2.0960.17 0.154 0.173 7.37

2.179 0.099 0.11 8.7810.166 0.15 0.168 5.1630.184 0.167 0.187 7.03547.2 9.28 9.458 5.754

0.158 0.144 0.161 2.8670.184 0.167 0.187 0.1850.241 0.218 0.244 2.9060.203 0.184 0.206 0.612

64.528 12.002 10.861 3.8050.201 0.183 0.204 12.598.188 3.935 4.399 2.426

18.636 4.801 0.256 0.2540.206 0.187 0.209 6.017

0.3 0.273 0.305 8.480.196 0.178 0.199 4.3540.26 0.236 0.264 0.262

0.226 0.205 0.23 2.9620.177 0.161 0.18 9.094

35.436 10.45 8.926 1.954

EUBREC1072 EUBREC2816 EUBREC2817 RUMOBE035550.8361 0.6102 0.7634 2.71771.865 0.6737 0.7269 9.6923

9.9798 1.97 2.0192 6.820613.0628 2.543 2.3318 2.0756.3826 2.0609 1.5172 4.8393

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A. Proportional representation of assignable normalized RNA-Seq counts binned by KEGG category in fecal samples collected over time from singly- and multiply-treated animals.

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B. Proportional representation of assignable normalized RNA-Seq counts binned by KEGG pathway in fecal samples collected over time from singly- and multiply-treated animals.

Lipid Metabolism

Pyrimidine metabolism Fatty acid metabolism Sulfur metabolism Glutathione metabolism

0.0146 0.0060 0.0019 0.00650.0147 0.0062 0.0019 0.00530.0140 0.0039 0.0008 0.00330.0138 0.0061 0.0012 0.00400.0146 0.0062 0.0020 0.00530.0131 0.0077 0.0023 0.00590.0129 0.0088 0.0020 0.00590.0130 0.0072 0.0023 0.00660.0140 0.0121 0.0016 0.00400.0140 0.0102 0.0014 0.00300.0151 0.0038 0.0010 0.00380.0147 0.0074 0.0014 0.00520.0134 0.0055 0.0014 0.0037

Nucleotide Metabolism Energy MetabolismMetabolism of Other

Amino Acids

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0.0138 0.0039 0.0012 0.00260.0154 0.0035 0.0012 0.00350.0150 0.0038 0.0011 0.00310.0144 0.0047 0.0012 0.00340.0145 0.0034 0.0014 0.00370.0141 0.0101 0.0015 0.00310.0139 0.0099 0.0014 0.00290.0148 0.0033 0.0010 0.00370.0143 0.0028 0.0010 0.00250.0145 0.0035 0.0012 0.00320.0146 0.0030 0.0011 0.00300.0158 0.0043 0.0012 0.00200.0143 0.0029 0.0009 0.00340.0135 0.0048 0.0010 0.00240.0128 0.0050 0.0009 0.00390.0143 0.0057 0.0016 0.00410.0157 0.0043 0.0011 0.00180.0143 0.0030 0.0009 0.00340.0142 0.0046 0.0015 0.00520.0134 0.0044 0.0016 0.00570.0138 0.0061 0.0014 0.00570.0145 0.0050 0.0019 0.00440.0146 0.0050 0.0017 0.00410.0134 0.0058 0.0019 0.00660.0145 0.0066 0.0018 0.00650.0146 0.0026 0.0011 0.00480.0142 0.0033 0.0008 0.0033

0.0518 0.0179 0.0296 0.00450.0676 0.0170 0.0544 0.03350.0028 0.0035 0.0123 0.01460.1054 0.0033 0.0331 0.03620.0334 0.0491 0.0072 0.97760.2535 0.0215 0.1054 0.9831

C. Proportional representation of assignable normalized RNA-Seq counts binned by genes of interest in fecal samples collected over time from singly and multiply-treated animals.

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BACUNI_01158 BACUNI_01159 BDI_3373 BT_17591.855 0.446 19.678 0.4420.326 0.392 10.230 0.3881.239 0.165 0.166 0.1642.030 0.222 5.785 0.2190.377 6.792 9.994 0.4480.331 0.397 15.949 0.3940.173 0.208 8.558 0.2060.332 0.399 15.622 0.3950.413 0.993 6.727 0.7371.345 2.426 3.245 0.4004.577 0.250 4.013 0.2480.174 0.209 0.419 0.2070.432 0.260 1.041 2.0560.422 1.182 4.235 1.3370.172 0.207 0.207 0.2050.510 0.460 9.688 0.4550.889 0.178 11.249 0.1760.826 1.787 10.161 1.7700.506 1.519 5.180 0.3010.878 1.407 6.351 0.6970.191 6.442 0.231 7.2900.122 0.147 10.643 0.1460.186 0.224 7.179 0.2221.034 1.740 6.233 0.4920.677 2.439 3.671 0.4020.356 1.069 5.790 0.2120.207 0.249 12.986 0.2460.271 0.325 14.676 0.3220.228 0.274 10.174 0.2710.708 1.703 2.136 0.8432.041 0.818 3.555 4.8580.271 0.326 31.038 0.3230.283 0.341 10.592 0.3370.232 0.836 12.575 0.8282.030 1.219 34.263 0.4020.442 0.266 26.655 0.2630.293 0.352 51.940 2.7901.272 2.447 38.361 3.3310.199 0.239 10.326 1.659

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0.145 1.924 4.211 2.771

BACUNI_01158 BACUNI_01159 BDI_3373 BT_17590.842 1.244 9.595 0.3790.939 0.746 5.254 0.7450.442 2.198 5.591 1.7100.354 0.724 9.152 0.3790.721 0.877 22.352 1.756

BACOVA_04901 BACOVA_04902 BACOVA_04908 BACOVA_049254.997 10.177 0.497 2.0125.129 14.650 7.865 0.295

13.600 14.594 3.134 2.11618.229 11.507 2.718 0.16716.919 10.808 11.100 0.34141.575 19.795 4.871 1.4958.939 8.852 0.232 0.156

23.867 6.629 4.448 0.3009.743 5.154 0.830 0.1877.553 10.069 0.450 0.304

19.149 6.486 4.179 0.18839.836 23.213 6.057 1.73077.095 49.021 5.206 0.19533.116 15.593 6.396 0.76278.777 64.781 0.230 0.15641.806 24.495 15.883 0.80753.531 37.308 5.553 0.53568.257 31.117 11.506 1.79318.724 15.381 6.768 0.45729.564 10.949 3.135 0.79483.816 76.882 33.327 0.173

117.805 77.978 31.520 0.11164.326 63.577 9.218 1.514

123.955 60.088 14.676 1.87028.861 16.454 14.496 0.61291.847 52.351 14.529 0.16123.714 33.320 22.741 0.18778.944 45.877 7.244 0.245

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84.994 32.993 10.689 0.82527.831 27.387 27.508 0.64029.536 28.004 18.224 0.20561.442 33.793 6.531 0.24522.903 19.791 0.380 0.25649.949 17.284 11.172 0.20963.039 16.032 1.812 0.30684.869 37.467 2.664 0.60040.790 26.679 0.785 2.38444.572 14.601 1.023 0.46041.585 25.335 5.867 1.62170.245 42.650 12.861 0.921

BACOVA_04901 BACOVA_04902 BACOVA_04908 BACOVA_0492515.055 11.224 3.615 0.73745.985 27.834 6.491 0.74283.753 58.996 20.647 0.85661.466 38.386 16.542 0.41250.893 26.164 6.132 0.721

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0.00480.00420.00510.00460.00430.0047 *0.0051 *0.0041 *0.0046 *0.0047 *0.00590.00450.0043

Metabolism of Other Amino AcidsTaurine and hypotaurine metabolism

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0.00420.00470.0058 *0.0053 *0.0039 *0.0040 *0.0041 *0.0040 *0.0038 *0.0046 *0.0044 *0.0035 *0.0036 *0.0040 *0.0033 *0.0035 *0.0036 *0.00560.00320.00290.00310.00350.0041 *0.0038 *0.0034 *0.0034 *0.0048 *

0.87390.89300.13880.00010.04430.0100

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BT_1765 BT_3082 BVU_1663 BWH2_2464 RUMOBE_021725.583 1.474 3.683 7.135 0.5290.378 3.889 0.360 0.418 0.4650.159 0.182 4.557 0.883 2.1590.213 0.244 9.161 0.236 1.3150.436 0.499 0.831 0.483 0.5371.149 0.438 12.768 2.968 8.4872.204 1.605 1.910 1.998 1.4812.692 1.320 6.231 0.426 0.4740.478 2.190 1.824 2.385 3.2413.505 6.683 1.484 2.157 0.9595.780 3.582 0.230 0.267 11.8640.201 0.230 1.919 3.792 0.2482.250 7.723 5.480 0.277 0.3080.651 0.558 1.550 5.585 2.4044.779 10.251 14.232 0.221 0.2450.591 0.676 19.136 1.962 0.9091.029 3.923 2.287 1.329 2.5343.635 2.188 292.578 4.874 0.4712.048 2.343 1.673 2.593 1.0811.355 6.976 1.614 1.876 3.7550.221 4.310 34.005 0.245 0.2730.142 0.162 73.850 3.931 4.7192.585 0.493 0.205 0.239 0.2660.240 2.465 21.901 0.265 1.7690.391 3.136 14.182 3.036 0.9650.206 0.236 598.703 1.825 0.2540.240 0.274 125.898 14.342 0.2950.313 0.358 107.725 0.347 0.3860.264 0.906 378.912 4.679 2.6010.410 0.938 19.928 2.271 1.0100.262 2.704 888.826 3.199 8.0840.627 3.948 138.407 0.695 0.3870.328 4.504 22.822 0.364 0.4041.341 6.753 312.434 0.297 3.6343.133 5.824 157.872 7.809 0.9651.280 8.491 32.193 4.252 3.1526.785 2.329 193.330 6.764 6.2674.125 3.708 80.027 2.611 1.4512.536 2.374 337.280 2.299 1.988

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0.168 0.193 29.220 0.186 0.207

BT_1765 BT_3082 BVU_1663 BWH2_2464 RUMOBE_021721.680 1.852 4.281 1.909 1.9652.232 3.845 34.070 2.278 2.3820.716 2.113 28.829 1.543 1.5980.287 0.542 246.233 4.693 0.9092.059 4.083 219.241 2.848 2.654

BT_2254 BT_4109 BT_4110 BVU_1116 BVU_17982.218 0.836 0.502 4.155 7.6600.650 0.735 0.442 2.658 28.4550.274 0.620 1.119 10.934 20.8510.367 9.558 7.246 5.261 23.7130.750 0.848 0.510 0.383 0.864

11.861 0.745 4.478 3.704 49.3234.829 0.389 0.234 4.054 0.3970.662 0.748 0.450 0.338 9.1474.941 2.326 5.316 5.050 25.1334.022 3.788 2.733 1.713 29.335

13.265 0.469 6.479 28.596 45.82711.092 8.227 4.004 7.262 24.3511.721 17.996 5.556 10.775 23.2937.559 13.287 6.277 17.594 28.6912.057 0.387 0.233 0.175 0.395

11.437 13.500 14.334 17.791 40.3883.541 7.004 10.427 14.326 30.9254.610 5.210 9.397 24.900 28.8179.569 6.830 3.833 4.375 28.4172.916 10.544 5.547 4.469 40.291

12.971 2.587 0.519 16.959 18.01321.010 7.730 8.134 12.234 17.1611.112 18.436 2.771 18.565 25.1896.593 13.971 11.480 28.635 57.891

18.875 6.095 13.284 28.245 34.1573.899 5.608 2.409 9.418 35.511

88.731 26.586 0.280 21.932 19.9610.539 0.610 12.452 5.233 61.447

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9.998 4.622 8.029 9.289 17.7949.881 4.786 16.306 15.507 49.579

13.107 4.087 7.371 15.242 13.5330.540 21.968 3.669 6.070 23.6270.565 0.638 15.732 1.731 10.4043.232 2.610 0.314 3.539 5.8494.718 7.619 0.458 7.922 8.5393.524 7.966 4.789 16.657 34.4960.584 0.660 0.397 16.709 20.1741.522 6.305 1.034 1.555 8.7615.953 3.139 4.315 4.867 13.7115.219 3.605 23.055 51.417 30.722

BT_2254 BT_4109 BT_4110 BVU_1116 BVU_17983.057 2.059 2.303 3.825 19.4886.777 8.345 6.609 13.026 29.139

12.112 9.764 7.238 20.928 30.48222.610 8.442 7.895 12.276 36.8583.896 5.860 6.113 12.571 16.982

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RUMOBE_021741.5620.4585.4113.1080.5290.4642.1870.4664.3513.7787.0080.2446.9736.7040.2412.5075.1974.8712.4843.2867.7930.1722.6122.3225.2233.2460.290

15.9472.5610.9942.5470.3810.3984.5543.3244.3441.6451.4294.753

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4.086

RUMOBE_021742.2313.9523.6244.6082.746

BVU_1803 BVU_1815 BWH2_1718 BWH2_3569 BWH2_3615 BWH2_36171.045 9.850 5.160 4.350 9.157 8.847

14.714 3.713 7.133 9.295 8.459 8.5618.924 2.611 3.009 8.997 11.896 21.015

12.741 10.034 26.769 14.842 3.644 12.76410.619 21.916 0.748 5.051 0.465 22.46613.979 9.617 10.514 7.203 13.879 6.3107.562 6.567 4.129 6.091 0.213 11.9740.468 6.721 0.660 12.803 5.741 22.978

17.473 6.271 16.015 10.734 4.082 21.1947.585 2.127 23.398 10.147 1.246 16.0474.104 14.994 0.414 53.681 32.100 0.497

14.708 11.658 6.222 20.696 4.295 14.9378.217 20.482 0.859 14.476 3.732 35.0278.908 14.744 12.005 24.952 7.110 28.1460.242 0.218 18.116 0.288 34.820 60.716

25.162 17.579 4.056 33.125 9.604 29.20412.939 11.236 9.712 23.575 14.442 26.4927.917 11.074 7.552 5.814 4.488 16.946

16.027 5.752 26.618 17.363 10.919 25.92023.505 5.550 25.587 13.729 5.418 38.38719.694 6.294 0.380 7.378 2.364 16.89527.469 16.743 7.552 4.930 1.362 6.43323.072 16.704 0.370 13.094 11.484 35.50023.020 12.813 3.698 5.198 2.553 8.87740.043 16.255 11.428 14.738 3.758 35.50218.297 11.021 4.242 6.557 3.733 4.66627.434 8.381 0.411 12.840 0.255 11.8560.381 42.753 0.538 0.453 0.334 0.646

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18.961 10.093 4.532 0.382 3.378 0.54435.936 17.915 7.742 12.463 1.311 14.36113.744 6.023 4.958 7.982 1.960 21.6391.145 2.056 10.231 1.816 0.335 18.0960.399 0.358 0.563 4.274 0.350 8.1115.225 8.791 0.460 5.437 2.002 4.9756.674 8.983 3.361 11.337 4.593 22.592

13.707 20.686 18.451 6.297 0.273 12.6545.782 2.594 2.912 6.384 4.703 13.9793.228 6.437 8.599 9.383 3.770 13.9637.578 6.800 8.707 4.338 4.671 12.826

15.175 15.825 5.495 9.510 1.796 10.760

BVU_1803 BVU_1815 BWH2_1718 BWH2_3569 BWH2_3615 BWH2_36179.511 7.943 9.753 8.951 5.878 15.216

12.173 11.329 11.114 20.770 12.693 27.62726.660 13.762 4.686 9.068 4.304 20.64120.202 18.033 3.493 6.539 1.802 6.4157.266 7.855 6.374 6.676 2.445 13.960

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BWH2_4940 BWH2_4943 COLAER_008192.666 8.616 0.650

21.110 22.740 0.5722.262 10.332 0.2418.527 4.287 0.3230.387 0.673 0.660

11.545 0.591 0.5805.866 4.640 0.3030.341 9.498 0.5828.276 9.601 0.362

10.363 16.831 0.5890.214 4.461 0.3659.824 8.082 0.3054.657 7.332 0.3797.934 6.778 0.2460.177 49.482 0.3018.382 7.293 0.223

13.686 11.908 0.2604.242 5.905 0.579

13.235 20.322 0.4439.315 11.504 0.5130.196 0.342 0.3350.126 1.315 0.2153.821 11.636 0.3264.247 12.563 0.3633.126 10.880 0.5924.018 3.814 0.3124.891 0.370 0.3630.278 0.484 0.474

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0.234 0.407 0.4004.000 8.861 0.6213.726 7.701 0.3975.565 6.779 0.4750.291 3.544 0.4974.997 0.828 0.406

10.769 6.649 0.5923.859 8.690 0.3875.115 6.807 0.514

12.545 5.002 0.4463.681 3.915 0.3492.391 3.901 0.255

BWH2_4940 BWH2_4943 COLAER_008197.134 8.781 0.4867.167 13.307 0.3612.303 7.347 0.3662.684 2.787 0.4345.294 5.382 0.432

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Table S9. Model human gut microbiota membrane transport genes demonstrating more than or equal to fourfold increases or decreases in their expression after introduction of the FMP strain consortium.

Transcript Comparison Fold-regulation (>4-fold) K numberBT_1535 d14vd15 4x down K02003RUMOBE_04083 d14vd15 4x up K05833BACUNI_04256 d14vd15 4x up K02004BACWH2_2058 d14vd15 4x up K02004BACUNI_03549 d14vd15 4x up K06147CLOSCI_02660 d14vd42all 4x down K12511CLOSCI_02659 d14vd42all 4x down K12510RUMOBE_02632 d14vd15 4x up K11069BDI_3858 d14vd42all 4x down K02001BDI_2891 d14vd15 4x down K02237BACOVA_01204 d14vd42all 4x down K02238COLAER_00049 d14vd15 4x down K02015RUMOBE_00297 d14vd15 4x up K02006RUMOBE_00408 d14vd15 4x up K09817RUMOBE_00878 d14vd15 4x up K02013BVU_2054 d14vd42all 4x down K02015CLOSCI_02860 d14vd42all 4x down K02051CLOSCI_01336 d14vd42all 4x down K02049CLOSCI_01335 d14vd42all 4x down K02050CLOSCI_03939 d14vd15 4x down K02037BVU_3938 d14vd15 4x down K02038BVU_3939 d14vd15 4x down K02037BACUNI_04335 d14vd15 4x down K02038BVU_3940 d14vd15 4x down K02040DORLON_00313 d14vd15 4x down K02036BACCAC_02577 d14vd15 4x down K02037BDI_2592 d14vd15 4x down K02040DORLON_00310 d14vd15 4x down K02040BACUNI_04334 d14vd15 4x down K02036RUMOBE_00498 d14vd15 4x down K02040CLOSCI_02658 d14vd42all 4x down K02283CLOSCI_01606 d14vd42all 4x down K03100RUMOBE_02568 d14vd15 4x up K02027RUMOBE_03599 d14vd15 4x up K11189RUMOBE_03134 d14vd42all 4x down K10117BACOVA_01794 d14vd42all 4x down K02100RUMOBE_03136 d14vd42all 4x down K02026CLOSCI_00732 d14vd42all 4x down K10117COLAER_01951 d14vd42all 4x down K10112BACOVA_01817 d14vd42all 4x down K02100BDI_1536 d14vd42all 4x down K08223RUMOBE_03135 d14vd42all 4x down K02025BACUNI_02077 d14vd42all 4x down K08139RUMOBE_03137 d14vd42all 4x down K02026COLAER_00133 d14vd42all 4x up K02809;K02

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BVU_1664 d14vd42all 4x up K02429DORLON_00416 d14vd42all 4x up K10439CLOSCI_01965 d14vd42all 4x up K02058DORLON_02306 d14vd42all 4x up K10441DORLON_01092 d14vd42all 4x up K02755;K02CLOSCI_03479 d14vd15 4x down K02062

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Table S9. Model human gut microbiota membrane transport genes demonstrating more than or equal to fourfold increases or decreases in their expression after introduction of the FMP strain consortium.

KEGG pathway KEGG categoryTransporters MEMBRANE TRANSPORTTransporters MEMBRANE TRANSPORTTransporters MEMBRANE TRANSPORTTransporters MEMBRANE TRANSPORTTransporters MEMBRANE TRANSPORTSecretion system MEMBRANE TRANSPORTSecretion system MEMBRANE TRANSPORTTransporters;ABC transporters MEMBRANE TRANSPORTTransporters;ABC transporters MEMBRANE TRANSPORTSecretion system MEMBRANE TRANSPORTSecretion system MEMBRANE TRANSPORTTransporters;ABC transporters MEMBRANE TRANSPORTTransporters;ABC transporters MEMBRANE TRANSPORTTransporters;ABC transporters MEMBRANE TRANSPORTTransporters;ABC transporters MEMBRANE TRANSPORTTransporters;ABC transporters MEMBRANE TRANSPORTTransporters;ABC transporters MEMBRANE TRANSPORTTransporters;ABC transporters MEMBRANE TRANSPORTTransporters;ABC transporters MEMBRANE TRANSPORTTransporters;ABC transporters MEMBRANE TRANSPORTTransporters;ABC transporters MEMBRANE TRANSPORTTransporters;ABC transporters MEMBRANE TRANSPORTTransporters;ABC transporters MEMBRANE TRANSPORTTransporters;ABC transporters;Two-compoMEMBRANE TRANSPORT;SIGNAL TRANSDUTransporters;ABC transporters MEMBRANE TRANSPORTTransporters;ABC transporters MEMBRANE TRANSPORTTransporters;ABC transporters;Two-compoMEMBRANE TRANSPORT;SIGNAL TRANSDUTransporters;ABC transporters;Two-compoMEMBRANE TRANSPORT;SIGNAL TRANSDUTransporters;ABC transporters MEMBRANE TRANSPORTTransporters;ABC transporters;Two-compoMEMBRANE TRANSPORT;SIGNAL TRANSDUSecretion system;Bacterial motility protein MEMBRANE TRANSPORT;CELL MOTILITYPeptidases;Protein export ENZYME FAMILIES;MEMBRANE TRANSPORTransporters MEMBRANE TRANSPORTTransporters MEMBRANE TRANSPORTTransporters;ABC transporters MEMBRANE TRANSPORTTransporters MEMBRANE TRANSPORTTransporters MEMBRANE TRANSPORTTransporters;ABC transporters MEMBRANE TRANSPORTTransporters;ABC transporters MEMBRANE TRANSPORTTransporters MEMBRANE TRANSPORTTransporters MEMBRANE TRANSPORTTransporters MEMBRANE TRANSPORTTransporters;Meiosis - yeast MEMBRANE TRANSPORT;CELL GROWTH ATransporters MEMBRANE TRANSPORTStarch and sucrose metabolism;TransporteCARBOHYDRATE METABOLISM;MEMBRANE

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Transporters MEMBRANE TRANSPORTTransporters;ABC transporters;Bacterial c MEMBRANE TRANSPORT;CELL MOTILITYTransporters MEMBRANE TRANSPORTTransporters;ABC transporters MEMBRANE TRANSPORTTransporters;Phosphotransferase system ( MEMBRANE TRANSPORT;UNPROCESSED|MTransporters;ABC transporters MEMBRANE TRANSPORT

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Table S9. Model human gut microbiota membrane transport genes demonstrating more than or equal to fourfold increases or decreases in their expression after introduction of the FMP strain consortium.

Annotation ECABC.CD.A NOT DEFINEDputative ABC transport system ATP-binding protein NOT DEFINEDABC.CD.P NOT DEFINEDABC.CD.P NOT DEFINEDATP-binding cassette, subfamily B, bacterial NOT DEFINEDtight adherence protein C NOT DEFINEDtight adherence protein B NOT DEFINEDspermidine/putrescine transport system substrate-binding protein NOT DEFINEDglycine betaine/proline transport system permease protein NOT DEFINEDcompetence protein ComEA NOT DEFINEDcompetence protein ComEC NOT DEFINEDiron complex transport system permease protein NOT DEFINEDcobalt/nickel transport system ATP-binding protein NOT DEFINEDzinc transport system ATP-binding protein [EC:3.6.3.-] EC3.6.3.-iron complex transport system ATP-binding protein [EC:3.6.3.34] EC3.6.3.34iron complex transport system permease protein NOT DEFINEDsulfonate/nitrate/taurine transport system substrate-binding proteNOT DEFINEDsulfonate/nitrate/taurine transport system ATP-binding protein NOT DEFINEDsulfonate/nitrate/taurine transport system permease protein NOT DEFINEDphosphate transport system permease protein NOT DEFINEDphosphate transport system permease protein NOT DEFINEDphosphate transport system permease protein NOT DEFINEDphosphate transport system permease protein NOT DEFINEDphosphate transport system substrate-binding protein NOT DEFINEDphosphate transport system ATP-binding protein [EC:3.6.3.27] EC3.6.3.27phosphate transport system permease protein NOT DEFINEDphosphate transport system substrate-binding protein NOT DEFINEDphosphate transport system substrate-binding protein NOT DEFINEDphosphate transport system ATP-binding protein [EC:3.6.3.27] EC3.6.3.27phosphate transport system substrate-binding protein NOT DEFINEDpilus assembly protein CpaF NOT DEFINEDsignal peptidase I [EC:3.4.21.89] EC3.4.21.89multiple sugar transport system substrate-binding protein NOT DEFINEDphosphocarrier protein NOT DEFINEDmultiple sugar transport system substrate-binding protein NOT DEFINEDMFS transporter, SP family, arabinose:H+ symporter NOT DEFINEDmultiple sugar transport system permease protein NOT DEFINEDmultiple sugar transport system substrate-binding protein NOT DEFINEDmaltose/maltodextrin transport system ATP-binding protein NOT DEFINEDMFS transporter, SP family, arabinose:H+ symporter NOT DEFINEDMFS transporter, FSR family, fosmidomycin resistance protein NOT DEFINEDmultiple sugar transport system permease protein NOT DEFINEDMFS transporter, SP family, sugar:H+ symporter NOT DEFINEDmultiple sugar transport system permease protein NOT DEFINEDPTS system, sucrose-specific IIB component [EC:2.7.1.69]|PTS syst EC2.7.1.69

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MFS transporter, FHS family, L-fucose permease NOT DEFINEDribose transport system substrate-binding protein NOT DEFINEDsimple sugar transport system substrate-binding protein NOT DEFINEDribose transport system ATP-binding protein [EC:3.6.3.17] EC3.6.3.17PTS system, beta-glucosides-specific IIA component [EC:2.7.1.69]| EC2.7.1.69thiamine transport system ATP-binding protein NOT DEFINED

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NoteABC transport systemABC transport systemABC transport systemABC transport systemABC transport systemadherence proteinadherence proteinamino acid transportamino acid transportcompetence proteincompetence proteinmetal transportmetal transportmetal transportmetal transportmetal transportorganic acid transportorganic acid transportorganic acid transportphosphate transportphosphate transportphosphate transportphosphate transportphosphate transportphosphate transportphosphate transportphosphate transportphosphate transportphosphate transportphosphate transportpilus assemblyprotein secretionsugar transportsugar transportsugar transportsugar transportsugar transportsugar transportsugar transportsugar transportsugar transportsugar transportsugar transportsugar transportsugar transport

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sugar transportsugar transportsugar transportsugar transportsugar transportvitamin transport

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Table S10. Bottom-up (gene-level) analysis of the impact of the FMP strain consortium on the model community's metatranscriptome.

A. Breakdown by species of significantly up/down-regulated genes.

SpeciesB. caccaeB. ovatusB. uniformisP. distasonisB. thetaiotaomicronB. vulgatusB. WH2C. aerofaciensC. scindensC. spiroformeD. longicatenaR. obeumR. torques

"early" = d15 relative to d14"late" = d42 relative to d14

B. Breakdown by KEGG category of significantly up/down-regulated genes.

CategoryXENOBIOTICS BIODEGRADATION AND METABOLISMTRANSPORT AND CATABOLISMTRANSLATION PROTEINSTRANSLATIONTRANSCRIPTION RELATED PROTEINSTRANSCRIPTIONSPORULATIONSIGNALING MOLECULES AND INTERACTIONSIGNAL TRANSDUCTION MECHANISMSSIGNAL TRANSDUCTIONRESTRICTION ENZYMEREPLICATION, RECOMBINATION AND REPAIR PROTEINSREPLICATION AND REPAIRPROTEIN FOLDING AND ASSOCIATED PROCESSINGPORES ION CHANNELSOTHERSOTHER TRANSPORTERSOTHER ION-COUPLED TRANSPORTERSNUCLEOTIDE METABOLISM

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METABOLISM OF OTHER AMINO ACIDSMETABOLISM OF COFACTORS AND VITAMINSMEMBRANE TRANSPORTMEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULESLIPID METABOLISMINORGANIC ION TRANSPORT AND METABOLISMGLYCAN BIOSYNTHESIS AND METABOLISMGENERAL FUNCTION PREDICTION ONLYFOLDING, SORTING AND DEGRADATIONENZYME FAMILIESENERGY METABOLISMCELL MOTILITY AND SECRETIONCELL MOTILITYCELL GROWTH AND DEATHCARBOHYDRATE METABOLISMBIOSYNTHESIS OF SECONDARY METABOLITESBIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDESAMINO ACID METABOLISM

UNKNOWN

"early" = d15 relative to d14"late" = d42 relative to d14

C. Model community microbiome genes demonstrating significant increases/decreases in expression following introduction of the FMP consortium.

GeneBACWH2_2416BVU_2695BT_1970RUMOBE_04083BACWH2_3936BVU_2921RUMOBE_02860RUMOBE_03730RUMOBE_01283BACUNI_04256RUMOBE_02632RUMOBE_03072BT_2260BACWH2_5207RUMOBE_01591BT_4174

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RUMOBE_00703RUMOBE_01324BVU_2006BACOVA_00299RUMOBE_04201BT_4166RUMOBE_03100BT_4171RUMOBE_00297RUMOBE_00983BACWH2_1072RUMOBE_01650RUMOBE_03071RUMOBE_02972BT_0883RUMOBE_03900CLOSCI_02284RUMOBE_00408BACOVA_04070BACUNI_04180BACOVA_04122RUMOBE_03751RUMOBE_02568RUMOBE_01689RUMOBE_01319BACUNI_02074BT_2709BACOVA_02850RUMOBE_00455RUMOBE_03866BT_4109COLAER_01182RUMOBE_00117BT_3382BT_3990BVU_1507BACWH2_2058BACOVA_02538RUMOBE_00485RUMOBE_03178BT_4145BACUNI_00657BVU_1411RUMOBE_02380

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BT_1683RUMOBE_03599BT_1501COLAER_00658BACUNI_04092BVU_0594COLAER_01017BT_0299BT_2092BACOVA_04575BT_2161BACUNI_03549BT_2705RUMOBE_00481BACWH2_3450COLAER_02091RUMOBE_00878BACOVA_04927RUMOBE_02005RUMOBE_00246BACWH2_4781RUMOBE_00311BACOVA_05621BACCAC_03032RUMOBE_01270BT_4183BVU_1901BACWH2_2592BDI_3278RUMOBE_03414RUMOBE_03833CLOSCI_02124BT_3680BT_3195BACUNI_03548RUMOBE_02885BACWH2_3656BT_3191RUMTOR_02840BVU_3009BACWH2_3777BACWH2_2108BACWH2_4624BACWH2_4623

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CLOSCI_03939BT_2912BACUNI_01079BVU_3938BVU_2990RUMOBE_04229CLOSCI_03479BVU_3939BVU_4095BACCAC_03626BACOVA_00022BT_1083BACWH2_0184BT_3064BACWH2_4635BDI_3957BACUNI_04335BT_1535BVU_2228BACCAC_00270BDI_2288BDI_0808BVU_3039BVU_3936BACOVA_01294BACUNI_01057BVU_3940BDI_1770BDI_2285DORLON_00313BDI_2803BT_1073BACWH2_2213BACUNI_03370BACCAC_03236BACCAC_02577RUMTOR_02521BACWH2_3773BACUNI_03391BVU_3365BACUNI_01370BDI_2593CLOSCI_02152BVU_2855

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BDI_2592BACCAC_03316RUMTOR_02914DORLON_00310BACUNI_04334CLOSCI_04006BACWH2_0415BACCAC_01371BDI_2891BACOVA_01449CLOSCI_00398BACCAC_00268RUMTOR_01514CLOSCI_04026BACWH2_2579CLOSCI_02005CLOSCI_02560BACOVA_05310BDI_2700CLOSCI_02842BACCAC_02052BDI_2257BACCAC_03007BACOVA_03151BVU_0765CLOSCI_03874BDI_1373BACUNI_00283BVU_2991BACUNI_02202BDI_3711BT_3741BACWH2_2091RUMOBE_00714BT_1813BACOVA_04548COLAER_00049BACWH2_3771RUMTOR_00609BACOVA_03777BT_3276BACOVA_02054RUMOBE_00498BVU_2669

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COLAER_00462CLOSCI_02520BACOVA_02719BACOVA_00310BT_0355BACOVA_00302BACOVA_00305BACOVA_04387BACOVA_00301BT_4270BACWH2_1693BACOVA_00304BACOVA_00300BT_4267BACOVA_00308BACOVA_00306BT_0349BACOVA_00307BDI_2951BT_0351BT_4272BT_2709BT_0347BACOVA_00309BACOVA_02064BT_0350BACOVA_04392BT_4610BACOVA_04390BACOVA_04393BT_0883BACWH2_5438BACOVA_00303CLOSCI_02284BDI_1439BT_3236BT_3223BT_4266BT_4271COLAER_00133BACWH2_1692BT_4269BACUNI_02983BACOVA_04386

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BDI_3086BDI_2728BACWH2_2592BACOVA_04385BT_2723BT_0354BDI_0472BACOVA_00294BACWH2_3506BACCAC_01430BT_0212BACOVA_04388BT_3225BACOVA_00299BT_0645BT_1633BVU_1665BACOVA_00298BACWH2_1590BACUNI_02968BT_0353BT_4268BT_1654BVU_1664BT_4589BDI_3085BACUNI_02951BACWH2_1695BVU_1662BT_3222BT_3745BT_3224DORLON_00372BACOVA_00130BVU_1507BACUNI_02953CLOSCI_03078BDI_1195BACWH2_1593BACWH2_4853BACUNI_02985BACOVA_00296BACOVA_04391BT_2238

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BVU_2456BDI_3087BACWH2_1592BACWH2_3505BACUNI_02975BT_4235BACCAC_02533CLOSCI_03539BVU_2949BVU_2459BDI_2952BACWH2_3358BACOVA_00550BVU_1663BT_0206BACUNI_02986BACOVA_02908BT_0348BT_0211CLOSCI_03536BACUNI_02981BVU_0464DORLON_00368BT_1936BACWH2_1703BACWH2_3360COLAER_00552BVU_3508BDI_0048BT_4684DORLON_00369BACUNI_02974BACWH2_3383BT_2260BACWH2_3359BACWH2_0229BACWH2_3378BDI_2730COLAER_00118BDI_2844BACWH2_1702RUMOBE_03072DORLON_00416BT_1620

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BACUNI_02987BDI_2640BACWH2_0305BACWH2_3365RUMOBE_01667RUMTOR_02599DORLON_00383CLOSCI_03132COLAER_00132BT_1192BACOVA_04341BT_2161BACUNI_02961COLAER_02091DORLON_00371BACCAC_00065BACCAC_02540BACCAC_02538BACWH2_3382BACWH2_3361BACWH2_3364BACUNI_02971BACUNI_02984BACWH2_3367COLAER_00750BACWH2_3384BACWH2_3366BACWH2_3380BACWH2_4298BT_3990BACUNI_02988COLAER_02090BDI_3637BACWH2_3376BDI_2953BACCAC_03152RUMOBE_01591CLOSCI_00319COLAER_01343BACUNI_02958BDI_3615BDI_1558BT_0152BACUNI_02980

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CLOSCI_02601COLAER_01108BACUNI_02960COLAER_01676BACUNI_02964BDI_3624RUMOBE_04058BACWH2_3377CLOSCI_02290BACWH2_1989BACWH2_3372BT_3743BACUNI_02955BACWH2_2000BT_4013RUMOBE_00571BACWH2_4927BACWH2_0528BACWH2_3371BACWH2_3373BACWH2_3379CLOSCI_01965BACWH2_3869BDI_3662COLAER_00355CLOSCI_02745COLAER_01859COLAER_01893BT_0210BACOVA_00670BDI_1560BACUNI_02954BACWH2_1694COLAER_01862BDI_3630RUMOBE_02860BACWH2_1990CLOSCI_01515BACWH2_3689BVU_3405BACWH2_0327BT_4404BVU_1190BT_2297

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RUMOBE_03424RUMTOR_01289BACWH2_3363RUMOBE_03707COLAER_02427BACUNI_02982CLOSCI_00286CLOSCI_00390BT_1655COLAER_00759COLAER_02100DORLON_02306BACUNI_02970BACWH2_1985COLAER_02391COLAER_01327DORLON_01092BDI_2996BACWH2_0712COLAER_02066BACOVA_01800BACOVA_04408BACWH2_1689BVU_4046BACOVA_01801BACOVA_01792CLOSCI_03123BACOVA_00116BVU_0582BACCAC_01092CLOSCI_02648CLOSCI_02661CLOSCI_01385BVU_1286CLOSCI_00690CLOSCI_01606BACWH2_0526CLOSCI_03108BVU_4030CLOSCI_02649CLOSCI_02650CLOSCI_02636BACOVA_01802CLOSCI_01781

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CLOSCI_02657BACCAC_01091BACUNI_03778BACOVA_01814CLOSCI_01607CLOSCI_00992CLOSCI_00720CLOSCI_00060BACUNI_01285BACUNI_02568BACOVA_01793BACUNI_01082BVU_4013BVU_4045CLOSCI_03126BACWH2_3560BACOVA_01799BVU_0692BVU_1542BVU_4017CLOSCI_02663BACOVA_01797CLOSCI_02660BACOVA_01808CLOSCI_00041BACOVA_01796BACWH2_3568BVU_0210CLOSCI_01384BACOVA_02607BACOVA_01809BACWH2_3561BACUNI_01080BACUNI_03782CLOSCI_00415BACOVA_05287BACWH2_1688CLOSCI_01131BACCAC_00920BACUNI_00339CLOSCI_00419BVU_4050CLOSCI_01117CLOSCI_00422

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BACOVA_01798BACUNI_03777BT_4249CLOSCI_01992BACUNI_00914CLOSCI_01604BVU_0506CLOSCI_01817CLOSCI_02665BACUNI_02294BACUNI_01084CLOSCI_03687CLOSCI_00991RUMOBE_03134CLOSCI_02026CLOSCI_01306BACOVA_04105CLOSCI_00420BVU_2433BVU_4033CLOSCI_03208BACOVA_01794CLOSCI_01398BVU_0683BVU_1551CLOSCI_01130BACWH2_3566CLOSCI_01111BACOVA_01204CLOSCI_02658BACUNI_01087CLOSCI_00352CLOSCI_01096BT_3028BVU_1724BACUNI_02031RUMTOR_02669BACOVA_04103BACOVA_01803CLOSCI_01605CLOSCI_02651CLOSCI_01095CLOSCI_01307BACUNI_01079

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BACWH2_1337CLOSCI_03206BACUNI_02549BVU_0584BACOVA_05141BACUNI_03783CLOSCI_02664CLOSCI_02537CLOSCI_03124CLOSCI_02860BACOVA_01813CLOSCI_00416CLOSCI_00721BACOVA_01795BACWH2_0524BACOVA_01811BACOVA_04107CLOSCI_02012CLOSCI_03127CLOSCI_01336CLOSCI_04025BACOVA_00109BACCAC_00903BVU_0681BVU_1553BACUNI_03781BACWH2_5241BACUNI_02076CLOSCI_01097BVU_0559CLOSCI_01603BDI_3116CLOSCI_02655CLOSCI_02011BACOVA_04132CLOSCI_01335BACUNI_03767CLOSCI_02643RUMOBE_03136BACOVA_01812BACUNI_01086BACWH2_2377BACOVA_04104CLOSCI_03590

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CLOSCI_03125BACCAC_03795CLOSCI_00732CLOSCI_00147CLOSCI_02267RUMOBE_03142CLOSCI_02676BACUNI_01088BACUNI_00460BACUNI_03776BACUNI_01101BACCAC_00921COLAER_01951BACUNI_02235CLOSCI_03683BACUNI_00828CLOSCI_03179BVU_1277BACUNI_03237CLOSCI_00592BACUNI_01255BACOVA_01810BT_2486BACUNI_04720BACUNI_02552BACUNI_04419CLOSCI_02013BACCAC_00583BVU_4039BACUNI_00443BACWH2_3567BDI_1591BVU_4036BACOVA_01817BVU_1733BACOVA_02165BACOVA_05465BACUNI_02616CLOSCI_00722BVU_4035BVU_1197RUMOBE_00372BACUNI_02081BACWH2_2182

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CLOSCI_02266CLOSCI_00435CLOSCI_02265BACOVA_02525CLOSCI_02345BACUNI_00683BVU_4022BACOVA_01475CLOSCI_00417CLOSCI_04026BVU_1384CLOSCI_01427CLOSCI_00421BACOVA_00758BACUNI_02269BACUNI_00122BDI_1417BACUNI_03214BACUNI_01825BACCAC_00924CLOSCI_02261BACOVA_01815BACOVA_02579BACOVA_00022CLOSCI_01428BACUNI_02252CLOSPI_00953RUMTOR_01863CLOSCI_01389BVU_4048BACUNI_02086CLOSCI_02659BACUNI_00261BACUNI_01085CLOSCI_01124CLOSCI_01729CLOSCI_03855BACCAC_03158BACUNI_03537BACWH2_4878CLOSCI_02540BACUNI_02259BVU_4023CLOSCI_04027

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BVU_4040BACUNI_01935BACUNI_01638BACUNI_02079BACUNI_02060BDI_1536BVU_2750CLOSCI_01780BACUNI_02579CLOSCI_00591BVU_1287BACCAC_03485BACOVA_04567BACUNI_00706BVU_4043BACCAC_01692BACCAC_02114BVU_2054BACUNI_02559BACUNI_04329BACOVA_03297CLOSCI_01985BACOVA_00890BDI_0322BACWH2_3081CLOSCI_01065BACOVA_01816BACOVA_05170BACUNI_00886BACOVA_02068BVU_4028BACWH2_3893BACOVA_03153BDI_1579RUMOBE_03135BACOVA_05235BACCAC_00474BDI_3822BDI_3120CLOSCI_00418BACUNI_04273BACUNI_02560CLOSCI_02859BACUNI_02077

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BT_0865BACUNI_03745BACUNI_02080BACWH2_3245CLOSCI_02264RUMTOR_00416RUMOBE_03137BACCAC_02904BACUNI_04176BDI_3840BACCAC_03257BDI_3408BVU_4041RUMOBE_01532BACUNI_00338BACUNI_03808RUMTOR_01445BACUNI_01143BACOVA_01294BACUNI_03624BACUNI_02253CLOSCI_02997BACUNI_03099RUMOBE_02037BDI_2707BACUNI_00580BDI_0611CLOSCI_03674BACOVA_05422BACUNI_02802BACOVA_02524BACCAC_00582BACUNI_01081BACOVA_02719CLOSCI_00045BDI_3817BACUNI_02263BACUNI_02191RUMOBE_01708BACOVA_02602BVU_3714CLOSCI_00342CLOSCI_01310CLOSCI_03559

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CLOSCI_00754BDI_1419BDI_1418RUMTOR_01497BT_1889BVU_4019CLOSCI_03421CLOSCI_02635CLOSCI_00719CLOSCI_00970BACOVA_01249BT_4090BACOVA_05310RUMOBE_00958BACUNI_01417BT_2921BACUNI_01083BACUNI_03807RUMTOR_00317BDI_3816BACCAC_01316BACOVA_04091CLOSCI_03778CLOSCI_03420BT_4694BACUNI_01972CLOSCI_01252RUMOBE_03578BDI_3858BACUNI_00280CLOSCI_03860BVU_0703BACCAC_00580BVU_3515BVU_0292BACUNI_03747BACUNI_02261BVU_4031BACUNI_02255BACWH2_4409BDI_1522BVU_4006BACUNI_00699BDI_0590

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BACOVA_04548BVU_3740BACUNI_03068BDI_0813

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Table S10. Bottom-up (gene-level) analysis of the impact of the FMP strain consortium on the model community's metatranscriptome.

Up ≥ 4x (early) Down ≥ 4x (early) Up ≥ 4x (late) Down ≥ 4x (late)1 9 6 188 9 29 577 9 22 811 13 22 20

20 9 48 87 14 12 469 12 47 184 2 20 12 11 13 1130 0 0 10 2 8 0

38 3 8 110 5 2 6

Up ≥ 4X (early) Down ≥ 4x (early) Up ≥ 4x (late) Down ≥ 4x (late)0 2 2 60 1 0 42 0 0 05 0 6 31 0 0 03 3 5 110 2 0 260 0 1 21 1 0 10 7 2 80 1 1 00 0 2 43 1 5 50 3 1 21 0 1 53 3 9 110 1 0 23 0 6 52 2 4 4

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4 0 2 13 2 5 5

10 15 6 201 0 2 41 0 5 100 2 0 12 3 4 244 3 7 40 2 1 21 1 1 84 1 2 30 2 0 00 0 1 10 0 0 1

10 3 34 401 3 3 50 0 1 06 5 8 10

36 42 126 186

C. Model community microbiome genes demonstrating significant increases/decreases in expression following introduction of the FMP consortium.

p-value Fold-change K number KEGG category(ies)3.56E-05 4.317691481 K01224 OTHERS6.24E-05 4.190726478 K01190 CARBOHYDRATE METAB

0.000108589 4.726248336 K00262 ENERGY METABOLISM;0.000162514 6.897938904 K05833 MEMBRANE TRANSPO0.000254685 5.969183359 Unknown UNKNOWN0.000287147 4.426020505 Unknown UNKNOWN0.000883897 5.860693745 K01868 TRANSLATION0.001126819 4.699048324 Unknown UNKNOWN0.001584868 4.096754097 K01735 AMINO ACID METABOL0.002297229 4.271735724 K02004 MEMBRANE TRANSPO0.002571769 4.79132066 K11069 MEMBRANE TRANSPO0.002634512 9.105207499 Unknown UNKNOWN0.002893179 7.468603587 Unknown UNKNOWN0.00324667 5.814923923 K01417 OTHERS

0.003679447 4.138376014 Unknown UNKNOWN0.003844044 6.098771895 K00810 METABOLISM OF COFA

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0.004079898 4.914682645 K00532 CARBOHYDRATE META0.004209032 4.27237972 Unknown UNKNOWN0.004423639 4.659523281 K01704 CARBOHYDRATE METAB0.004520782 9.154702584 Unknown UNKNOWN0.004664344 4.843968735 K06158 TRANSLATION PROTEI0.004714484 5.47414982 Unknown UNKNOWN0.005009136 4.529483963 K03151 METABOLISM OF COFA0.005318847 9.952110754 Unknown UNKNOWN0.005485608 4.465051258 K02006 MEMBRANE TRANSPO0.005864384 5.417633807 K06306 GERMINATION0.005906589 4.163032199 K01424 ENERGY METABOLISM;0.005959423 4.286651992 K07050 GENERAL FUNCTION PR0.006002024 4.81819749 Unknown UNKNOWN0.006616534 4.203740715 K01436 AMINO ACID METABOL0.006792114 5.150821239 K07164 GENERAL FUNCTION PR0.006837984 7.511677943 K03458 OTHER ION-COUPLED 0.00689994 4.457469458 Unknown UNKNOWN

0.006925916 4.173465476 K09817 MEMBRANE TRANSPO0.007184806 4.590219301 Unknown UNKNOWN0.007713261 4.546567051 K01811 CARBOHYDRATE META0.008187552 4.026566193 K01213 CARBOHYDRATE META0.008331753 4.431590758 K01409 ENZYME FAMILIES0.008421938 6.178344865 K02027 MEMBRANE TRANSPO0.00854699 5.450550559 K00969 METABOLISM OF COFA

0.009389734 4.20026787 Unknown UNKNOWN0.009746783 4.206651044 Unknown UNKNOWN0.009872176 9.097563795 K02907 TRANSLATION0.009975274 4.605582097 Unknown UNKNOWN0.010513851 4.021423156 K03660 REPLICATION AND REP0.010541167 4.120262353 K01005 METABOLISM OF OTHE0.01081242 4.130539115 K01051 CARBOHYDRATE META

0.011681333 4.093879536 K03655 REPLICATION AND REP0.012512897 4.58908788 K02529 TRANSCRIPTION0.013359332 4.591568825 Unknown UNKNOWN0.01342939 4.101119555 Unknown UNKNOWN

0.013547956 5.230765592 K07133 GENERAL FUNCTION PR0.015241096 4.188026668 K02004 MEMBRANE TRANSPO0.015512745 4.056350639 K01506 OTHERS0.017231514 4.651699495 K01921 METABOLISM OF OTHE0.017418405 5.602653619 Unknown UNKNOWN0.017839676 4.057283769 Unknown UNKNOWN0.017897351 4.233846116 K00041 CARBOHYDRATE META0.018182327 4.016033387 Unknown UNKNOWN0.019672212 5.973496612 K02338 NUCLEOTIDE METABOL

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0.020027346 4.166156936 Unknown UNKNOWN0.020987478 4.132439527 K11189 MEMBRANE TRANSPO0.021049757 6.36039865 K03286 PORES ION CHANNELS0.021216906 4.364655144 Unknown UNKNOWN0.021541799 4.064365005 Unknown UNKNOWN0.022704392 7.829272854 K03402 TRANSCRIPTION0.026247361 4.572473276 K03624 TRANSCRIPTION RELAT0.026606707 4.996426976 K03296 OTHER ION-COUPLED 0.02690559 4.329122933 K07085 GENERAL FUNCTION PR

0.027310413 4.109727767 Unknown UNKNOWN0.027628628 4.106021886 K02939 TRANSLATION0.028811385 5.997178925 K06147 MEMBRANE TRANSPO0.028898943 4.75526482 K02518 TRANSLATION0.029779555 5.531283021 Unknown UNKNOWN0.029902707 7.346767089 Unknown UNKNOWN0.031768277 5.371369091 Unknown UNKNOWN0.032064077 4.484780866 K02013 MEMBRANE TRANSPO0.032904548 4.823092118 K01188 CARBOHYDRATE METAB0.033307092 4.890563995 K00688 CARBOHYDRATE METAB0.033400519 5.573557135 K00014 AMINO ACID METABOL0.033699782 5.762885304 K03327 OTHER ION-COUPLED 0.034673935 6.016171176 K02587 ENERGY METABOLISM0.035600065 5.51758408 Unknown UNKNOWN0.038245541 4.041526108 K02939 TRANSLATION0.038617112 8.479332956 Unknown UNKNOWN0.038849446 4.749599298 K01728 CARBOHYDRATE META0.040803465 4.523000428 Unknown UNKNOWN0.04142982 4.249037639 K03931 FUNCTION UNKNOWN

0.041469888 4.908798318 Unknown UNKNOWN0.043892341 4.040992986 K01514 NUCLEOTIDE METABOL0.045117893 4.045127865 K07183 SIGNAL TRANSDUCTIO0.045454399 4.219114966 Unknown UNKNOWN0.047303108 4.729814257 Unknown UNKNOWN0.047433127 4.448170806 K06168 TRANSLATION PROTEI0.047653599 6.40826553 K02022 MEMBRANE AND INTRA0.047939724 6.282029503 K07729 TRANSCRIPTION0.049159513 5.386844196 Unknown UNKNOWN0.001428544 0.202835276 Unknown UNKNOWN0.001462771 0.241443618 Unknown UNKNOWN0.001691232 0.081979506 Unknown UNKNOWN0.002067096 0.226405081 Unknown UNKNOWN0.00269938 0.211480131 K01090 OTHERS

0.003183158 0.206378262 K01133 INORGANIC ION TRAN0.003302693 0.247360352 Unknown UNKNOWN

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0.003633361 0.151206936 K02037 MEMBRANE TRANSPO0.003665407 0.15660392 K01209 CARBOHYDRATE META0.004503412 0.217523048 K01785 CARBOHYDRATE META0.00513203 0.113166715 K02038 MEMBRANE TRANSPO

0.005404223 0.165821991 K00937 ENERGY METABOLISM;0.005535 0.224207914 Unknown UNKNOWN

0.007040054 0.201083542 K02062 MEMBRANE TRANSPO0.007172006 0.142354889 K02037 MEMBRANE TRANSPO0.007871557 0.214124953 K07658 SIGNAL TRANSDUCTIO0.008899546 0.244643456 Unknown UNKNOWN0.009846904 0.160977377 K00609 NUCLEOTIDE METABOL0.010565372 0.226788571 K03978 GENERAL FUNCTION PR0.011362806 0.239123071 Unknown UNKNOWN0.011408125 0.248821038 Unknown UNKNOWN0.01163779 0.246474224 K03931 FUNCTION UNKNOWN

0.011709174 0.222612348 K02231 METABOLISM OF COFA0.012133973 0.154649199 K02038 MEMBRANE TRANSPO0.01271426 0.222576011 K02003 MEMBRANE TRANSPO

0.012994106 0.234882408 Unknown UNKNOWN0.013065689 0.198066035 K03559 CELL MOTILITY AND S0.013100972 0.233048266 K02527 GLYCAN BIOSYNTHESI0.013468747 0.190654793 K07658 SIGNAL TRANSDUCTIO0.013600906 0.170745059 Unknown UNKNOWN0.01368772 0.076371265 K02039 INORGANIC ION TRAN

0.014179213 0.146415724 Unknown UNKNOWN0.014179507 0.226096111 K04047 REPLICATION AND REP0.014392613 0.086183051 K02040 MEMBRANE TRANSPOR0.014628452 0.180875542 K05882 OTHERS0.014650432 0.172392129 K01467 BIOSYNTHESIS OF SEC0.016675446 0.199228799 K02036 MEMBRANE TRANSPO0.016700643 0.215970867 K07391 PROTEIN FOLDING AND0.017079142 0.137132063 Unknown UNKNOWN0.017613882 0.154511568 Unknown UNKNOWN0.01866171 0.215662034 K07011 GENERAL FUNCTION PR

0.018953964 0.236685984 Unknown UNKNOWN0.019142916 0.063333629 K02037 MEMBRANE TRANSPO0.019446404 0.164549267 K03686 FOLDING, SORTING A0.020155253 0.174001061 Unknown UNKNOWN0.021123121 0.24381397 Unknown UNKNOWN0.021134901 0.243352848 Unknown UNKNOWN0.021619696 0.248898746 Unknown UNKNOWN0.021690218 0.13993808 Unknown UNKNOWN0.022364148 0.180874315 K03577 TRANSCRIPTION0.022395233 0.16677173 K01156 RESTRICTION ENZYME

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0.022401077 0.238249403 K02040 MEMBRANE TRANSPOR0.022990417 0.235465396 K01940 AMINO ACID METABOL0.02369199 0.153493605 Unknown UNKNOWN

0.023943144 0.114994412 K02040 MEMBRANE TRANSPOR0.025042726 0.179176046 K02036 MEMBRANE TRANSPO0.025759624 0.224188848 K07027 GENERAL FUNCTION PR0.026030917 0.20216259 K07165 SIGNAL TRANSDUCTIO0.026071686 0.222673903 K01195 CARBOHYDRATE METAB0.02654584 0.211644695 K02237 MEMBRANE TRANSPO

0.026707763 0.185375369 Unknown UNKNOWN0.027064676 0.233219286 K06385 SPORULATION0.028114654 0.217859513 K03561 CELL MOTILITY AND S0.029600568 0.200531626 Unknown UNKNOWN0.031358458 0.235291262 K06333 SPORULATION0.031898398 0.14514616 Unknown UNKNOWN0.03291901 0.231603538 K02529 TRANSCRIPTION

0.032919613 0.246975197 Unknown UNKNOWN0.033318775 0.151706745 K05595 OTHER TRANSPORTERS0.033705285 0.233455789 K00991 BIOSYNTHESIS OF SEC0.033798304 0.216708993 Unknown UNKNOWN0.034800548 0.22104151 Unknown UNKNOWN0.035282622 0.218520669 K00147 AMINO ACID METABOL0.037143303 0.227913173 Unknown UNKNOWN0.037572849 0.169562022 K01269 AMINO ACID METABOL0.038355981 0.194910278 Unknown UNKNOWN0.038818455 0.235705811 K01259 AMINO ACID METABOL0.040715809 0.213407912 K03976 FUNCTION UNKNOWN0.041597291 0.155997904 Unknown UNKNOWN0.042644909 0.220206058 K01514 NUCLEOTIDE METABOL0.043475226 0.193340247 Unknown UNKNOWN0.04350511 0.20836662 K00992 OTHERS

0.043514248 0.241896279 Unknown UNKNOWN0.044091897 0.178419652 Unknown UNKNOWN0.044828906 0.211409077 K01607 XENOBIOTICS BIODEG0.045049288 0.205398588 K03760 GLYCAN BIOSYNTHESI0.045380886 0.172391842 Unknown UNKNOWN0.046040613 0.212737435 K02015 MEMBRANE TRANSPO0.047261074 0.15333911 Unknown UNKNOWN0.047343038 0.240817575 Unknown UNKNOWN0.047750146 0.195254877 Unknown UNKNOWN0.047842376 0.223851165 Unknown UNKNOWN0.048255397 0.160110688 K05521 PROTEIN FOLDING AND0.048501546 0.218362928 K02040 MEMBRANE TRANSPOR0.048643228 0.208674556 K05785 TRANSCRIPTION

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0.049089493 0.143728728 Unknown UNKNOWN0.049361069 0.234662785 K04069 PROTEIN FOLDING AND0.04967774 0.192452535 Unknown UNKNOWN

2.63E-07 7.446441636 Unknown UNKNOWN5.87E-07 7.768715518 K03307 OTHER ION-COUPLED 1.14E-06 9.796593048 Unknown UNKNOWN1.62E-06 6.657751 Unknown UNKNOWN4.85E-06 5.213290517 K01181 CARBOHYDRATE META6.20E-06 6.922207952 Unknown UNKNOWN6.33E-06 50.41110609 Unknown UNKNOWN9.46E-06 13.57997739 Unknown UNKNOWN9.48E-06 4.297901735 Unknown UNKNOWN1.02E-05 6.990136178 K01362 AMINO ACID METABOL1.28E-05 127.632123 Unknown UNKNOWN1.43E-05 5.255096835 K01206 GLYCAN BIOSYNTHESI2.96E-05 5.010413448 Unknown UNKNOWN3.06E-05 7.120673486 K09955 FUNCTION UNKNOWN3.35E-05 5.407811256 K02199 FOLDING, SORTING A3.51E-05 26.57457027 K00639 AMINO ACID METABOL3.87E-05 7.287976036 K01804 CARBOHYDRATE META4.00E-05 54.77799052 Unknown UNKNOWN4.03E-05 8.449285565 K02907 TRANSLATION5.94E-05 5.534343723 K00615 CARBOHYDRATE METAB5.99E-05 8.110732197 Unknown UNKNOWN6.23E-05 4.695079245 Unknown UNKNOWN7.16E-05 5.259404237 K00853 CARBOHYDRATE META9.02E-05 7.389378421 Unknown UNKNOWN9.89E-05 4.922760218 K03553 REPLICATION AND REP9.98E-05 10.95059878 K01181 CARBOHYDRATE META

0.000118115 5.763085743 Unknown UNKNOWN0.000119489 5.829413294 K07164 GENERAL FUNCTION PR0.000140783 4.542585031 Unknown UNKNOWN0.000159182 4.570455368 Unknown UNKNOWN0.000196339 5.084854869 Unknown UNKNOWN0.000199494 6.287405308 K01119;K08693 NUCLEOTIDE METABOL0.00020922 4.195689545 Unknown UNKNOWN

0.000218528 5.663262625 Unknown UNKNOWN0.000227584 51.03776756 Unknown UNKNOWN0.000259966 13.2842625 Unknown UNKNOWN0.000293714 31.75865295 K02809;K02810 CARBOHYDRATE META0.000302836 14.73149568 Unknown UNKNOWN0.000326074 28.41747296 Unknown UNKNOWN0.000337994 8.865579106 Unknown UNKNOWN0.000349261 4.672637985 K01209 CARBOHYDRATE META

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0.000361243 8.671444935 Unknown UNKNOWN0.000401767 7.544706009 Unknown UNKNOWN0.000406518 4.939727687 K03931 FUNCTION UNKNOWN0.000423288 4.577809618 K01235 CARBOHYDRATE META0.000443096 4.567076649 K02965 TRANSLATION0.000515304 4.915721932 K01529 OTHERS0.000537885 5.562672289 Unknown UNKNOWN0.000575654 4.396966149 K05905 PROTEIN FOLDING AND0.000585277 5.569627399 Unknown UNKNOWN0.000602797 5.486027833 Unknown UNKNOWN0.000622769 9.171344398 K01362 AMINO ACID METABOL0.000670222 4.21594049 K03292 OTHER ION-COUPLED 0.000689829 4.125595861 Unknown UNKNOWN0.000732775 20.31202 Unknown UNKNOWN0.000754626 4.456412386 Unknown UNKNOWN0.000755224 5.002917728 K00966 CARBOHYDRATE META0.00076775 6.752862347 K00847 CARBOHYDRATE META

0.000769505 6.91594984 K03911 IMMUNE SYSTEM0.000868875 4.823173416 Unknown UNKNOWN0.000875392 14.96799698 K09459 METABOLISM OF OTHE0.000923207 4.578423947 K03077 CARBOHYDRATE META0.000937954 387.6201702 Unknown UNKNOWN0.000947958 4.289108853 K01991 PORES ION CHANNELS0.000958059 39.09553638 K02429 MEMBRANE TRANSPO0.001007325 4.532885496 K02897 TRANSLATION0.001069082 5.969316976 Unknown UNKNOWN0.001126481 5.762745748 K01784 CARBOHYDRATE META0.001313683 6.855793576 Unknown UNKNOWN0.001320679 102.194294 Unknown UNKNOWN0.001340544 6.157552387 Unknown UNKNOWN0.001404454 4.288986823 Unknown UNKNOWN0.001586012 7.643803326 K06966 GENERAL FUNCTION PR0.001594097 6.782001773 K00945 NUCLEOTIDE METABOL0.001628232 4.49060046 Unknown UNKNOWN0.001659843 7.301584799 K07133 GENERAL FUNCTION PR0.001788086 5.754674282 K01043 OTHERS0.001845096 4.161064554 Unknown UNKNOWN0.001938012 4.391480969 Unknown UNKNOWN0.001975284 4.562180764 Unknown UNKNOWN0.002012651 4.225273465 K07720 SIGNAL TRANSDUCTIO0.002308098 13.28581449 K00983 CARBOHYDRATE META0.002324785 5.133609904 Unknown UNKNOWN0.002332327 4.830507782 Unknown UNKNOWN0.002354243 5.093895204 K03524 METABOLISM OF COFA

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0.002357056 8.895819187 Unknown UNKNOWN0.002370504 4.859035523 Unknown UNKNOWN0.002449636 4.209836887 Unknown UNKNOWN0.002581253 5.217954544 Unknown UNKNOWN0.002581901 11.0828931 Unknown UNKNOWN0.00263707 4.658062113 Unknown UNKNOWN

0.002956123 4.617817532 Unknown UNKNOWN0.003202692 4.255609212 Unknown UNKNOWN0.003256381 5.866834433 Unknown UNKNOWN0.003527371 8.082749135 Unknown UNKNOWN0.003605233 5.073174794 Unknown UNKNOWN0.003728618 14.26330883 K05785 TRANSCRIPTION0.003778104 4.267055175 Unknown UNKNOWN0.003808593 52.07888628 K01212 CARBOHYDRATE META0.004050743 8.744245321 Unknown UNKNOWN0.004198232 9.788911786 K00837 AMINO ACID METABOL0.004234426 4.166961189 Unknown UNKNOWN0.004295932 4.587895432 K01209 CARBOHYDRATE META0.004359815 5.21492951 Unknown UNKNOWN0.004411455 4.16469712 Unknown UNKNOWN0.004415258 9.979825092 K01654 CARBOHYDRATE META0.004421863 4.334952466 K01495 METABOLISM OF COFA0.00451735 9.669971419 K03335 CARBOHYDRATE META

0.004657221 4.344002733 Unknown UNKNOWN0.004674075 4.06697763 Unknown UNKNOWN0.004696328 14.58639203 Unknown UNKNOWN0.004715285 4.666173118 Unknown UNKNOWN0.004912846 4.231577109 K01734 CARBOHYDRATE META0.004947453 4.860756041 K08070 OTHERS0.004947493 6.503719128 K01238 OTHERS0.005198555 6.845929621 K00010 CARBOHYDRATE METAB0.005450722 4.889033781 Unknown UNKNOWN0.005495579 7.868724727 K01784 CARBOHYDRATE META0.005585387 5.120746373 Unknown UNKNOWN0.005590603 10.66041012 Unknown UNKNOWN0.005815378 4.823496632 Unknown UNKNOWN0.005856167 13.94289679 K02474 CARBOHYDRATE METAB0.005879284 4.835728261 K03088 TRANSCRIPTION0.005920457 4.407143153 K02316 REPLICATION AND REP0.006009997 4.374259593 Unknown UNKNOWN0.006335438 5.065222062 Unknown UNKNOWN0.006406714 4.378604988 Unknown UNKNOWN0.006501841 4.132625182 K10439 MEMBRANE TRANSPORT0.006567102 4.469066579 Unknown UNKNOWN

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0.006599256 10.87876065 K00100;K01726 CARBOHYDRATE METAB0.006648652 7.201815124 Unknown UNKNOWN0.006845722 4.254796091 Unknown UNKNOWN0.006888349 9.103248487 Unknown UNKNOWN0.006889641 4.213747912 K08641 ENZYME FAMILIES0.007171871 15.1712774 Unknown UNKNOWN0.007999344 4.079390729 K03317 OTHER ION-COUPLED 0.008081056 5.563856934 K08298 OTHERS0.008102104 20.86271736 K01193 CARBOHYDRATE META0.008262001 5.236253449 K05968 OTHERS0.008288146 4.5559492 K00936 OTHERS0.008354398 4.781795258 K02939 TRANSLATION0.008421374 6.246801344 Unknown UNKNOWN0.008943688 5.723439245 Unknown UNKNOWN0.009109353 8.517043055 K03292 OTHER ION-COUPLED 0.00924321 4.01223745 Unknown UNKNOWN

0.009334228 7.742717915 K00754 CARBOHYDRATE META0.009459643 4.873248431 Unknown UNKNOWN0.009504162 18.99909272 K01711 CARBOHYDRATE META0.009722231 7.552687728 K00441 METABOLISM OF COFA0.010052016 5.519600563 Unknown UNKNOWN0.010168137 8.117389408 K00839 AMINO ACID METABOL0.010325357 10.78980398 Unknown UNKNOWN0.011459117 13.81023404 Unknown UNKNOWN0.011585621 5.919456238 K03431 CARBOHYDRATE META0.011684676 6.04742927 K13007 GLYCAN BIOSYNTHESI0.011700946 8.867610149 Unknown UNKNOWN0.011914101 5.502073751 K00638 OTHERS0.011944451 6.048939144 Unknown UNKNOWN0.01285498 4.026491108 Unknown UNKNOWN

0.013045896 5.028100092 Unknown UNKNOWN0.013332281 4.083365335 Unknown UNKNOWN0.013351237 4.872184681 Unknown UNKNOWN0.013903318 10.87580594 K00754 CARBOHYDRATE META0.014013729 8.542974151 K11031 SIGNALING MOLECULE0.01428288 5.645707306 K01071 LIPID METABOLISM

0.014472495 4.304158414 Unknown UNKNOWN0.014475131 4.586448869 Unknown UNKNOWN0.014503755 4.33274709 K02879 TRANSLATION0.015031757 9.94817344 K00968 LIPID METABOLISM;M0.015061557 6.28377455 K00100;K01726 CARBOHYDRATE METAB0.015146025 7.122644167 Unknown UNKNOWN0.01586941 4.007355382 K01070 ENERGY METABOLISM

0.015994402 5.769447792 K01447 MEMBRANE AND INTRA

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0.016927763 4.096770783 K03657 REPLICATION AND REP0.017686853 6.487240264 K03436 TRANSCRIPTION0.017932138 4.237346371 Unknown UNKNOWN0.018063567 5.568328281 Unknown UNKNOWN0.018340136 5.080733973 Unknown UNKNOWN0.01837158 5.522957463 K00754 CARBOHYDRATE META

0.018787256 4.825209289 K02492 METABOLISM OF COFA0.019530359 5.959133121 Unknown UNKNOWN0.019975128 4.252616691 K01012 METABOLISM OF COFA0.021117656 4.343600894 K00754 CARBOHYDRATE META0.021366289 4.122326634 Unknown UNKNOWN0.021514863 4.932595533 Unknown UNKNOWN0.02197358 6.099658938 K03328 OTHER ION-COUPLED

0.022126245 5.00820521 Unknown UNKNOWN0.023308533 13.56683776 K01155 RESTRICTION ENZYME0.023354667 6.002644941 K04763 REPLICATION AND REP0.023428143 4.143969763 Unknown UNKNOWN0.024187132 5.182698853 K09955 FUNCTION UNKNOWN0.024261558 8.828022177 Unknown UNKNOWN0.024481726 4.034381201 K00075 CARBOHYDRATE METAB0.024861464 8.73821802 Unknown UNKNOWN0.025096512 5.71854802 K02058 MEMBRANE TRANSPO0.025335904 5.066379418 Unknown UNKNOWN0.026260153 4.26067959 K06871 GENERAL FUNCTION PR0.026293877 5.762632378 K00837 AMINO ACID METABOL0.026311814 4.269849413 Unknown UNKNOWN0.026462623 4.42715272 K03481 TRANSCRIPTION0.026621861 5.571627202 Unknown UNKNOWN0.026777783 7.62112123 K06883 GENERAL FUNCTION PR0.027341869 4.833348465 Unknown UNKNOWN0.027531877 5.051940399 Unknown UNKNOWN0.027656213 4.043223494 K07271 MEMBRANE AND INTRA0.028082039 5.906558865 Unknown UNKNOWN0.028790959 5.251922652 K07133 GENERAL FUNCTION PR0.030403666 5.095553163 K00059 LIPID METABOLISM0.030697499 5.137121584 K01868 TRANSLATION

0.0308792 4.473531129 K00754 CARBOHYDRATE META0.031637026 4.064112308 Unknown UNKNOWN0.03182298 6.524954604 K06907 GENERAL FUNCTION PR

0.031898051 4.598107703 K01091 CARBOHYDRATE META0.034107718 4.215244721 Unknown UNKNOWN0.034489289 4.560505801 Unknown UNKNOWN0.034760728 5.429981189 K03424 REPLICATION, RECOMB0.036031944 4.199354806 K00986 REPLICATION, RECOMB

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0.036430237 5.046227006 K00609 NUCLEOTIDE METABOL0.036868509 4.045111559 K07775 SIGNAL TRANSDUCTIO0.037771885 7.492508731 Unknown UNKNOWN0.037957067 4.545428273 Unknown UNKNOWN0.038042174 4.424606938 Unknown UNKNOWN0.038086707 7.575126966 K01955 NUCLEOTIDE METABOL0.039168085 6.541595083 Unknown UNKNOWN0.039321303 4.353399161 Unknown UNKNOWN0.040340851 6.213598495 Unknown UNKNOWN0.041123176 4.464929971 K01552 OTHERS0.041290077 4.020613082 Unknown UNKNOWN0.042157319 6.604845899 K10441 MEMBRANE TRANSPO0.042661142 6.229360383 Unknown UNKNOWN0.043758954 5.293373692 K00754 CARBOHYDRATE META0.043958391 5.961650622 K06218 FUNCTION UNKNOWN0.044339848 4.498063972 Unknown UNKNOWN0.045382285 6.44512553 K02755;K02756;K0275 MEMBRANE TRANSPOR0.045679803 4.306193723 Unknown UNKNOWN0.04690574 4.012939035 K03298 OTHER ION-COUPLED

0.049137962 4.469434413 K03572 REPLICATION AND REP9.21E-07 0.0271138360034271 Unknown UNKNOWN1.09E-06 0.12276414125864 Unknown UNKNOWN1.36E-06 0.138485136627095 Unknown UNKNOWN2.81E-06 0.0424939703191439 Unknown UNKNOWN5.64E-06 0.0383897336393018 Unknown UNKNOWN5.95E-06 0.0596252876463996 Unknown UNKNOWN6.50E-06 0.116136278403579 K06387 SPORULATION7.71E-06 0.233494492142439 Unknown UNKNOWN1.17E-05 0.208141209543844 Unknown UNKNOWN1.29E-05 0.0061715647961315 Unknown UNKNOWN1.49E-05 0.148022450377948 Unknown UNKNOWN1.59E-05 0.100129252586658 Unknown UNKNOWN1.78E-05 0.0437291745190508 K07258 GLYCAN BIOSYNTHESIS1.83E-05 0.107118617182985 Unknown UNKNOWN2.14E-05 0.0214848153850034 K06398 SPORULATION2.34E-05 0.0554010502442468 K03100 ENZYME FAMILIES;ME2.45E-05 0.190086764573347 Unknown UNKNOWN2.71E-05 0.0493363343401971 K06283 TRANSCRIPTION3.07E-05 0.0597637021269296 K01709 CARBOHYDRATE META4.71E-05 0.137528817248566 Unknown UNKNOWN4.74E-05 0.182956808392421 K06306 GERMINATION5.36E-05 0.0170945359234099 K06386 SPORULATION5.42E-05 0.0302059360949074 K05970 OTHERS6.37E-05 0.0403098217413742 Unknown UNKNOWN

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7.09E-05 0.0917347463243648 Unknown UNKNOWN7.33E-05 0.0128296459823154 Unknown UNKNOWN7.47E-05 0.0303214529470937 Unknown UNKNOWN8.50E-05 0.059015583791382 Unknown UNKNOWN9.27E-05 0.0263515184087609 Unknown UNKNOWN

0.00010072 0.0446571170574632 Unknown UNKNOWN0.000101437 0.0381218022674587 K01463 METABOLISM OF COFA0.000108497 0.134899248704643 Unknown UNKNOWN0.00010887 0.16358486299618 K07678 ENZYME FAMILIES;SIG

0.000112582 0.174797549355978 K01791 CARBOHYDRATE METAB0.000132872 0.0434056612588087 Unknown UNKNOWN0.00014812 0.181363920628417 K05989 OTHERS

0.000148761 0.034991594674292 K01529 OTHERS0.000152684 0.0865990013765145 K01726 CARBOHYDRATE METAB0.000153868 0.0265793668002019 Unknown UNKNOWN0.00015612 0.191970627289985 Unknown UNKNOWN

0.000167724 0.0463283107891218 Unknown UNKNOWN0.000175295 0.205073130814392 K01791 CARBOHYDRATE METAB0.000175295 0.205073130814392 K01791 CARBOHYDRATE METAB0.000181987 0.0555180012055667 Unknown UNKNOWN0.000223867 0.137524348409118 Unknown UNKNOWN0.000224003 0.0221595392332084 Unknown UNKNOWN0.000224758 0.0916809971476089 K12511 MEMBRANE TRANSPO0.00022616 0.0734206773611078 K05970 OTHERS0.00026472 0.0380469072611319 K03091 TRANSCRIPTION

0.000278484 0.0310442262373791 Unknown UNKNOWN0.000284279 0.0459634613390544 Unknown UNKNOWN0.000293618 0.190042101050973 K03797 ENZYME FAMILIES0.000294883 0.0107752130551252 K06421 SPORULATION0.000312193 0.211012017253604 K03296 OTHER ION-COUPLED 0.000323754 0.0437428251405188 Unknown UNKNOWN0.000356594 0.201690883386818 Unknown UNKNOWN0.000363608 0.149441006731172 Unknown UNKNOWN0.000375175 0.0201253689775337 Unknown UNKNOWN0.000388998 0.0287871903893269 K06390 SPORULATION0.000460778 0.225194892284748 Unknown UNKNOWN0.000480406 0.137051971812227 Unknown UNKNOWN0.000485302 0.0258964438671548 Unknown UNKNOWN0.000494931 0.0866712994556337 K01991 PORES ION CHANNELS0.000497236 0.0415885346678145 Unknown UNKNOWN0.000505504 0.0331926504445695 K06394 SPORULATION0.000519844 0.0462790440471636 Unknown UNKNOWN0.000532003 0.0699061799574812 K03091 TRANSCRIPTION0.000539252 0.0202686937507277 K06397 SPORULATION

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0.000564805 0.0337352567680247 Unknown UNKNOWN0.000571505 0.074794586168002 Unknown UNKNOWN0.000584258 0.140433722859982 Unknown UNKNOWN0.000585885 0.151976899012866 K06382 SPORULATION0.000602925 0.0796617249609608 Unknown UNKNOWN0.000606444 0.0581160779507002 K08600 ENZYME FAMILIES0.000664243 0.24447801325322 Unknown UNKNOWN0.000669313 0.0849336842464756 Unknown UNKNOWN0.000676366 0.150521062230634 Unknown UNKNOWN0.000684632 0.161179573288195 K01412 ENZYME FAMILIES0.000746096 0.172943999060909 K01209 CARBOHYDRATE META0.000750601 0.080232736940988 Unknown UNKNOWN0.000784283 0.0490863701911723 K01500 XENOBIOTICS BIODEG0.000864394 0.160762849532896 K10117 MEMBRANE TRANSPO0.001016678 0.0721065950987751 Unknown UNKNOWN0.001049841 0.122842617151124 Unknown UNKNOWN0.001053127 0.192561728071362 K01227 GLYCAN BIOSYNTHESI0.001084233 0.0803603414283327 K06395 SPORULATION0.00113069 0.242432520510395 K01206 GLYCAN BIOSYNTHESI

0.001149771 0.205864233612955 Unknown UNKNOWN0.001233327 0.0338912578974184 Unknown UNKNOWN0.001284526 0.0310428606914996 K02100 MEMBRANE TRANSPO

0.0013001 0.0744156062075665 K06409 SPORULATION0.001318028 0.127998792313987 K01529 OTHERS0.001318028 0.127998792313987 K01529 OTHERS0.001356293 0.150262648862299 K04769 TRANSCRIPTION0.001403827 0.0768398207999176 Unknown UNKNOWN0.001412922 0.156598005300335 K03588 REPLICATION AND REP0.001442987 0.180958563201777 K02238 MEMBRANE TRANSPO0.001465097 0.113022894770096 K02283 MEMBRANE TRANSPORT0.001482816 0.180913741035466 Unknown UNKNOWN0.001484759 0.101442589779618 Unknown UNKNOWN0.001487318 0.0828726342765528 K06333 SPORULATION0.001491449 0.109923542048268 Unknown UNKNOWN0.001542245 0.0989695693227652 Unknown UNKNOWN0.00162765 0.17597510751578 K07029 GENERAL FUNCTION PR

0.001636486 0.190093422777495 K01447 MEMBRANE AND INTRA0.001708101 0.175738025814977 Unknown UNKNOWN0.001712385 0.0241866633880903 Unknown UNKNOWN0.001752418 0.0472184409248778 Unknown UNKNOWN0.00177808 0.0746636588083196 K01448 REPLICATION AND REP

0.001803881 0.0551736519659552 K06334 SPORULATION0.001826347 0.13807725784173 Unknown UNKNOWN0.001903753 0.142661450639904 K01785 CARBOHYDRATE META

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0.001915606 0.242816768120923 K03296 OTHER ION-COUPLED 0.001923345 0.168737322159641 K07045 GENERAL FUNCTION PR0.001973818 0.202707614047958 K07713 SIGNAL TRANSDUCTIO0.002011992 0.245309596977865 Unknown UNKNOWN0.002103986 0.204272939221556 K12373 CARBOHYDRATE METAB0.002108969 0.0277109318668525 Unknown UNKNOWN0.002114284 0.177882658563339 Unknown UNKNOWN0.002170637 0.025502229287319 K01448 REPLICATION AND REP0.002266552 0.0566615565270907 K11475 TRANSCRIPTION0.002287901 0.140387329546313 K02051 MEMBRANE TRANSPO0.002313151 0.108481495987358 Unknown UNKNOWN0.002330672 0.0478694314612919 K06391 SPORULATION0.002389158 0.0640045796556835 K04759 OTHER TRANSPORTERS0.002480534 0.0235361525354058 K01787 CARBOHYDRATE META0.002500576 0.192392774867496 K01190 CARBOHYDRATE METAB0.00251193 0.0362401577910386 Unknown UNKNOWN

0.002541446 0.152444967908146 Unknown UNKNOWN0.002587683 0.243740394524671 Unknown UNKNOWN0.002681117 0.0762997459140635 Unknown UNKNOWN0.002790781 0.10147532831606 K02049 MEMBRANE TRANSPO0.00282328 0.0966861503601421 K06334 SPORULATION

0.002881027 0.170951367699529 Unknown UNKNOWN0.002899902 0.186125586988312 K01784 CARBOHYDRATE META0.003123487 0.225235828810612 K07713 SIGNAL TRANSDUCTIO0.003123487 0.225235828810612 K07713 SIGNAL TRANSDUCTIO0.003162967 0.0373552666365253 Unknown UNKNOWN0.003245594 0.146689516212919 Unknown UNKNOWN0.003280742 0.164403757668051 Unknown UNKNOWN0.003312719 0.16523087204723 Unknown UNKNOWN0.003332885 0.143000150975269 Unknown UNKNOWN0.003364515 0.0539903494399192 Unknown UNKNOWN0.003379331 0.216797607070049 Unknown UNKNOWN0.003381122 0.0726181454527046 Unknown UNKNOWN0.003482034 0.0980493990776374 Unknown UNKNOWN0.003483265 0.173361378988305 K00936 OTHERS0.003565946 0.0337189728991123 K02050 MEMBRANE TRANSPO0.003823094 0.23892819326028 K07799 SIGNAL TRANSDUCTIO0.003842186 0.087142071077805 K01447 MEMBRANE AND INTRA0.003884963 0.155361000130647 K02026 MEMBRANE TRANSPO0.003911067 0.0888656756735604 Unknown UNKNOWN0.003954091 0.120938407076451 K01190 CARBOHYDRATE METAB0.003985376 0.181604269653672 Unknown UNKNOWN0.004040131 0.196498022963536 Unknown UNKNOWN0.004055343 0.135733426858623 K04565 TRANSPORT AND CATA

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0.00409887 0.119679303995567 K00919 BIOSYNTHESIS OF SEC0.004101294 0.235597674829344 K00527 NUCLEOTIDE METABOL0.004304204 0.171586214066441 K10117 MEMBRANE TRANSPO0.004328019 0.0898599815067439 K01506 OTHERS0.004397886 0.0920842335664502 K06379 SPORULATION0.004449817 0.229712108544925 K00688 CARBOHYDRATE METAB0.004548209 0.171485212621933 Unknown UNKNOWN0.004600961 0.166907756659227 Unknown UNKNOWN0.004706738 0.246083744179208 K02914 TRANSLATION0.004737843 0.113966752578649 Unknown UNKNOWN0.004817274 0.248036712528952 K02523 BIOSYNTHESIS OF SEC0.005010181 0.166382915910809 K05785 TRANSCRIPTION0.005049126 0.244910595030939 K10112 MEMBRANE TRANSPO0.005145091 0.14338574666145 K01726 CARBOHYDRATE METAB0.005305202 0.114110537904249 K03111 REPLICATION AND REP0.005462198 0.221466202309179 Unknown UNKNOWN0.005492871 0.0702591789094311 Unknown UNKNOWN0.005612523 0.209021821252746 K07720 SIGNAL TRANSDUCTIO0.00573698 0.104942132466155 Unknown UNKNOWN

0.005751409 0.124484666004361 Unknown UNKNOWN0.005754613 0.211147154345614 Unknown UNKNOWN0.005950092 0.0729330517148986 Unknown UNKNOWN0.006001175 0.227076871767751 Unknown UNKNOWN0.006109067 0.165676045136391 K01915 ENERGY METABOLISM;0.006112795 0.0773825459685462 K01529 OTHERS0.00621489 0.178633090800447 Unknown UNKNOWN

0.006296583 0.180279115474755 Unknown UNKNOWN0.006632871 0.133070830609306 Unknown UNKNOWN0.006650605 0.145452092402363 K00983 CARBOHYDRATE META0.006794997 0.236885901333279 Unknown UNKNOWN0.006989628 0.162053723405085 Unknown UNKNOWN0.00742435 0.247438218552947 Unknown UNKNOWN

0.007426013 0.0684078759101216 K01666 AMINO ACID METABOL0.007439706 0.13113148624189 K02100 MEMBRANE TRANSPO0.00752104 0.16034007025762 Unknown UNKNOWN

0.007687033 0.0981558765437906 Unknown UNKNOWN0.007714863 0.17617894027032 K01529 OTHERS0.00791743 0.0974051661159781 Unknown UNKNOWN

0.008083031 0.0732304147811409 K06306 GERMINATION0.008112524 0.0886366831736209 K03677 INORGANIC ION TRAN0.008153267 0.240369811839954 Unknown UNKNOWN0.008254656 0.157281835736361 Unknown UNKNOWN0.008373995 0.196733776462984 Unknown UNKNOWN0.008491332 0.169144212753113 Unknown UNKNOWN

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0.008497915 0.207825455546644 K03091 TRANSCRIPTION0.008782759 0.0894514365695422 K07699 SIGNAL TRANSDUCTIO0.009081865 0.126333978736741 Unknown UNKNOWN0.009193452 0.112564203502242 Unknown UNKNOWN0.009207814 0.0177135934708993 Unknown UNKNOWN0.009217716 0.180309658921841 K06223 REPLICATION AND REP0.009365559 0.112670260351321 K07484 REPLICATION, RECOMB0.009372162 0.23309224379566 Unknown UNKNOWN0.00948348 0.186458026678247 K06392 SPORULATION

0.009544272 0.0798345014817383 K06333 SPORULATION0.009550036 0.212703553165955 Unknown UNKNOWN0.009608044 0.100564599155255 K07301 OTHER ION-COUPLED 0.010015104 0.053898776950998 K06396 SPORULATION0.010254338 0.197461306565441 K01993 MEMBRANE AND INTRA0.010341509 0.0723983222360678 K01784 CARBOHYDRATE META0.01047611 0.120672126857324 Unknown UNKNOWN

0.010773351 0.130903959256825 Unknown UNKNOWN0.011160917 0.200282587154141 Unknown UNKNOWN0.011199384 0.167880779090019 K01685 CARBOHYDRATE META0.011232248 0.188059021343685 Unknown UNKNOWN0.011263168 0.1205220643172 K06406 SPORULATION0.01130779 0.0418316566291335 Unknown UNKNOWN

0.011715644 0.225635269150728 Unknown UNKNOWN0.011737276 0.182276131010948 K00609 NUCLEOTIDE METABOL0.011807812 0.213758709608509 K01788 CARBOHYDRATE META0.012044437 0.146272220293252 K01791 CARBOHYDRATE METAB0.012130473 0.155132729765599 K06419 SPORULATION0.012289865 0.219284689780752 K03308 OTHER ION-COUPLED 0.012352988 0.24853630606827 K07258 GLYCAN BIOSYNTHESIS0.012440296 0.177123611065366 Unknown UNKNOWN0.012451614 0.247755379556471 K03687 FOLDING, SORTING A0.012466027 0.127045531937377 K12510 MEMBRANE TRANSPO0.012806186 0.139679261389877 K10532 GLYCAN BIOSYNTHESI0.013018808 0.182851519138512 K06113 CARBOHYDRATE META0.01346101 0.0668162949885757 Unknown UNKNOWN

0.013679717 0.13456865805817 Unknown UNKNOWN0.013888966 0.0523067757561787 Unknown UNKNOWN0.014184455 0.175802584608496 K12344 LIPID METABOLISM;CA0.014200798 0.226238506067798 K00842 AMINO ACID METABOL0.014841442 0.205229020063894 Unknown UNKNOWN0.015206949 0.246699145938115 K00075 CARBOHYDRATE METAB0.015363057 0.096404189572989 K01711 CARBOHYDRATE META0.015856291 0.132717582641094 Unknown UNKNOWN0.015914272 0.188215724677747 Unknown UNKNOWN

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0.015930656 0.156118347666008 K01654 CARBOHYDRATE META0.016064808 0.13007674972576 Unknown UNKNOWN0.016106588 0.181497011438629 K00599 AMINO ACID METABOL0.016289946 0.129083622153334 Unknown UNKNOWN0.016632969 0.2294368670561 K07082 GENERAL FUNCTION PR0.016811824 0.208358935220458 K08223 MEMBRANE TRANSPO0.017307879 0.149114370654893 K02014 PORES ION CHANNELS0.017420496 0.116974783946203 Unknown UNKNOWN0.018138139 0.155543848088111 K00903 SIGNAL TRANSDUCTIO0.018323613 0.0743910911026584 K06438 SPORULATION0.018694638 0.222035247179372 Unknown UNKNOWN0.018769441 0.200544683411147 K02968 TRANSLATION0.018787994 0.236063219782119 Unknown UNKNOWN0.018821317 0.239664435795882 Unknown UNKNOWN0.019170928 0.0965927056383989 K01791 CARBOHYDRATE METAB0.019228471 0.219832103780318 K08307 GLYCAN BIOSYNTHESI0.01951448 0.182109381772235 Unknown UNKNOWN

0.019539472 0.247156045759134 K02015 MEMBRANE TRANSPO0.019708939 0.176187632586688 K01791 CARBOHYDRATE METAB0.019825775 0.151622463370365 K07058 GENERAL FUNCTION PR0.01984243 0.124824803847298 Unknown UNKNOWN

0.020057894 0.228730580040959 K06331 SPORULATION0.020132423 0.240882600264482 K01278 ENZYME FAMILIES;SIG0.020144069 0.22914755323533 K01778 AMINO ACID METABOL0.020453073 0.157247380404371 Unknown UNKNOWN0.020747422 0.218940574448892 Unknown UNKNOWN0.020853343 0.0335545014430551 K01787 CARBOHYDRATE META0.021076996 0.129855738869268 Unknown UNKNOWN0.021560102 0.203179932221727 K00850 CARBOHYDRATE META0.021689024 0.240895384768697 K03386 PROTEIN FOLDING AND0.021700681 0.184155191048981 K00978 CARBOHYDRATE META0.021839477 0.245299669772482 K01785 CARBOHYDRATE META0.021852509 0.158352721048155 Unknown UNKNOWN0.022575377 0.168601125562298 Unknown UNKNOWN0.023176896 0.189067784217097 K02025 MEMBRANE TRANSPO0.023505582 0.197294067395587 Unknown UNKNOWN0.023534383 0.173157776446659 Unknown UNKNOWN0.023622815 0.0839403402090237 K00012 CARBOHYDRATE META0.023838765 0.213802740659893 K01190 CARBOHYDRATE METAB0.023856508 0.0639619152949337 K06393 SPORULATION0.023943461 0.230889963948375 Unknown UNKNOWN0.024025498 0.249885357595642 K02852 GLYCAN BIOSYNTHESI0.024095863 0.202405452257361 Unknown UNKNOWN0.024158896 0.0870442038634723 K08139 MEMBRANE TRANSPOR

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0.024244834 0.217175966115294 K01114 CARBOHYDRATE METAB0.02425004 0.245624832057245 Unknown UNKNOWN

0.024474161 0.176519020049562 Unknown UNKNOWN0.024658694 0.245736890927312 K01126 LIPID METABOLISM0.025589036 0.230724050634108 K06403 SPORULATION0.026261021 0.140469308631581 Unknown UNKNOWN0.026276778 0.13753561965214 K02026 MEMBRANE TRANSPO0.026402347 0.226790139349711 K03088 TRANSCRIPTION0.026624382 0.21525016574661 Unknown UNKNOWN0.026945621 0.212999757446313 K02014 PORES ION CHANNELS0.027043534 0.235303748878646 K02914 TRANSLATION0.027059031 0.232521557296798 K02014 PORES ION CHANNELS0.027349447 0.181968402623707 K01955 NUCLEOTIDE METABOL0.027389595 0.151428773078481 K03712 TRANSCRIPTION0.027410939 0.147567826128813 Unknown UNKNOWN0.028006571 0.172955122448675 K01206 GLYCAN BIOSYNTHESI0.028010154 0.226211024286999 K00865 CARBOHYDRATE METAB0.028059388 0.183938175980499 K07493 REPLICATION, RECOMB0.028167797 0.236258288891419 Unknown UNKNOWN0.028737241 0.204095840056053 K00341 ENERGY METABOLISM0.028784694 0.22454475372801 K00100 CARBOHYDRATE METAB0.028790139 0.236832428358692 K06374 SPORULATION0.028987925 0.216501452878032 K09704 FUNCTION UNKNOWN0.029185136 0.166839773637368 Unknown UNKNOWN0.029552839 0.145130006578228 Unknown UNKNOWN0.030010863 0.216361780071222 Unknown UNKNOWN0.030013225 0.246549862280514 Unknown UNKNOWN0.030221636 0.178505622919803 K00560 NUCLEOTIDE METABOL0.030315099 0.116334609776914 Unknown UNKNOWN0.030529981 0.0992104171287206 Unknown UNKNOWN0.030605825 0.136171502675143 Unknown UNKNOWN0.031304977 0.0697574827955411 Unknown UNKNOWN0.031497094 0.208553694947451 K05989 OTHERS0.031668819 0.119208083501954 Unknown UNKNOWN0.031744745 0.185034397776125 K04096 REPLICATION, RECOMB0.031772797 0.123693113421484 Unknown UNKNOWN0.032416804 0.0992876480601733 Unknown UNKNOWN0.032578493 0.0307029634767464 Unknown UNKNOWN0.033168926 0.164338417340302 Unknown UNKNOWN0.033400743 0.24282382742802 K03088 TRANSCRIPTION0.033421707 0.197284311067119 Unknown UNKNOWN0.033542247 0.189904795486549 K00532 CARBOHYDRATE META0.033580707 0.0365199435680247 Unknown UNKNOWN0.033782612 0.214604426124138 Unknown UNKNOWN

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0.033939709 0.157400772145794 Unknown UNKNOWN0.034185813 0.115015090923628 Unknown UNKNOWN0.035177874 0.0718100005048243 K02851 GLYCAN BIOSYNTHESI0.035298772 0.234257155857967 Unknown UNKNOWN0.035517134 0.242179925327123 Unknown UNKNOWN0.03554102 0.122814564744492 K00754 CARBOHYDRATE META

0.035672345 0.195182568527117 Unknown UNKNOWN0.035767691 0.169222094794243 K06381 SPORULATION0.035990371 0.136129679737896 Unknown UNKNOWN0.036146088 0.0537773235051905 Unknown UNKNOWN0.036348448 0.219451205606857 Unknown UNKNOWN0.036744692 0.12022225368297 Unknown UNKNOWN0.036805805 0.164093112985531 K05595 OTHER TRANSPORTERS0.03721685 0.177146828360732 Unknown UNKNOWN

0.037543261 0.203665326635104 K03088 TRANSCRIPTION0.037852391 0.217501272802223 K00810 METABOLISM OF COFA0.038092791 0.219802384845941 K06113 CARBOHYDRATE META0.038343752 0.193463356494218 K01190 CARBOHYDRATE METAB0.038539355 0.206268875989715 K02224 METABOLISM OF COFA0.038738515 0.124865081515703 K13013 GLYCAN BIOSYNTHESI0.038997832 0.176122245111803 Unknown UNKNOWN0.039336562 0.248610747480601 Unknown UNKNOWN0.040053338 0.2194793700015 Unknown UNKNOWN0.040912519 0.205251442809989 Unknown UNKNOWN0.041272158 0.207607916283255 K07239 OTHER ION-COUPLED 0.042290339 0.147678971617751 K00919 BIOSYNTHESIS OF SEC0.042325293 0.179004795345142 Unknown UNKNOWN0.043008995 0.229529055110227 Unknown UNKNOWN0.043248164 0.23054079775279 K02001 MEMBRANE TRANSPO0.043422745 0.240776036768793 Unknown UNKNOWN0.043600624 0.0530554912614375 Unknown UNKNOWN0.044786194 0.149176029089878 K01991 PORES ION CHANNELS0.044898449 0.102474991121113 Unknown UNKNOWN0.045493864 0.221221975075072 K01834 CARBOHYDRATE META0.045674657 0.239072814975533 K02022 MEMBRANE AND INTRA0.045815628 0.204108659847047 K07460 REPLICATION, RECOMB0.046042801 0.201503322793823 K02377 CARBOHYDRATE META0.046250197 0.246474404667159 K13010 GLYCAN BIOSYNTHESI0.046733623 0.220407389005635 Unknown UNKNOWN

0.0467895 0.226392282438141 K10532 GLYCAN BIOSYNTHESI0.046853005 0.174606017685245 K07397 PROTEIN FOLDING AND0.047688032 0.249674372935097 K01778 AMINO ACID METABOL0.047838011 0.227145702233636 K00788 METABOLISM OF COFA0.047889355 0.221984782908058 K01658 AMINO ACID METABOL

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0.04799834 0.179634534746203 Unknown UNKNOWN0.048050877 0.235800497328668 Unknown UNKNOWN0.04847013 0.177356402864333 K01130 LIPID METABOLISM

0.049014719 0.215432537344986 Unknown UNKNOWN

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KEGG pathway(s) EC SpeciesUnclassified EC3.2.1.89 B. WH2Galactose metabolism;SEC3.2.1.23 B. vulgatusNitrogen metabolism;AlaEC1.4.1.4 B. thetaiotaomicronTransporters NOT DEFINED R. obeumUnknown Unknown B. WH2Unknown Unknown B. vulgatusAminoacyl-tRNA biosyntEC6.1.1.3 R. obeumUnknown Unknown R. obeumPhenylalanine, tyrosine EC4.2.3.4 R. obeumTransporters NOT DEFINED B. uniformisTransporters;ABC transpNOT DEFINED R. obeumUnknown Unknown R. obeumUnknown Unknown B. thetaiotaomicronUnclassified EC3.4.24.- B. WH2Unknown Unknown R. obeumUnclassified EC2.5.1.- B. thetaiotaomicron

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Glyoxylate and dicarbo EC1.12.7.2 R. obeumUnknown Unknown R. obeumC5-Branched dibasic aci EC4.2.1.33;EC4.2.1.35 B. vulgatusUnknown Unknown B. ovatusUnclassified NOT DEFINED R. obeumUnknown Unknown B. thetaiotaomicronThiamine metabolism NOT DEFINED R. obeumUnknown Unknown B. thetaiotaomicronTransporters;ABC transpNOT DEFINED R. obeumUnclassified NOT DEFINED R. obeumNitrogen metabolism;Al EC3.5.1.1 B. WH2Unclassified NOT DEFINED R. obeumUnknown Unknown R. obeumArginine and proline meEC3.5.1.14 R. obeumUnclassified NOT DEFINED B. thetaiotaomicronUnclassified NOT DEFINED R. obeumUnknown Unknown C. scindensTransporters;ABC transpEC3.6.3.- R. obeumUnknown Unknown B. ovatusUnclassified NOT DEFINED B. uniformisPentose and glucuronateEC3.2.1.67 B. ovatusPeptidases EC3.4.24.57 R. obeumTransporters NOT DEFINED R. obeumNicotinate and nicotin EC2.7.7.18 R. obeumUnknown Unknown R. obeumUnknown Unknown B. uniformisRibosome NOT DEFINED B. thetaiotaomicronUnknown Unknown B. ovatusBase excision repair;DN EC3.2.2.-;EC4.2.99.18 R. obeumPhosphonate and phospEC2.7.8.- R. obeumPentose and glucuronateEC3.1.1.11 B. thetaiotaomicronHomologous recombinatiEC3.6.1.- C. aerofaciensTranscription factors NOT DEFINED R. obeumUnknown Unknown B. thetaiotaomicronUnknown Unknown B. thetaiotaomicronUnclassified NOT DEFINED B. vulgatusTransporters NOT DEFINED B. WH2Unclassified EC3.5.-.- B. ovatusD-Alanine metabolism;PeEC6.3.2.4 R. obeumUnknown Unknown R. obeumUnknown Unknown B. thetaiotaomicronPentose and glucuronateEC1.1.1.58 B. uniformisUnknown Unknown B. vulgatusPurine metabolism;Pyri EC2.7.7.7 R. obeum

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Unknown Unknown B. thetaiotaomicronTransporters NOT DEFINED R. obeumUnclassified NOT DEFINED B. thetaiotaomicronUnknown Unknown C. aerofaciensUnknown Unknown B. uniformisTranscription factors NOT DEFINED B. vulgatusUnclassified NOT DEFINED C. aerofaciensUnclassified NOT DEFINED B. thetaiotaomicronUnclassified NOT DEFINED B. thetaiotaomicronUnknown Unknown B. ovatusRibosome NOT DEFINED B. thetaiotaomicronTransporters NOT DEFINED B. uniformisTranslation factors NOT DEFINED B. thetaiotaomicronUnknown Unknown R. obeumUnknown Unknown B. WH2Unknown Unknown C. aerofaciensTransporters;ABC transpEC3.6.3.34 R. obeumStarch and sucrose met EC3.2.1.21 B. ovatusStarch and sucrose metaEC2.4.1.1 R. obeumPhenylalanine, tyrosine EC1.1.1.25 R. obeumUnclassified NOT DEFINED B. WH2Nitrogen metabolism NOT DEFINED R. obeumUnknown Unknown B. ovatusRibosome NOT DEFINED B. caccaeUnknown Unknown R. obeumPentose and glucuronateEC4.2.2.2 B. thetaiotaomicronUnknown Unknown B. vulgatusUnclassified NOT DEFINED B. WH2Unknown Unknown P. distasonisPurine metabolism EC3.6.1.11 R. obeumUnclassified NOT DEFINED R. obeumUnknown Unknown C. scindensUnknown Unknown B. thetaiotaomicronUnclassified NOT DEFINED B. thetaiotaomicronUnclassified NOT DEFINED B. uniformisTranscription factors NOT DEFINED R. obeumUnknown Unknown B. WH2Unknown Unknown B. thetaiotaomicronUnknown Unknown R. torquesUnknown Unknown B. vulgatusUnknown Unknown B. WH2Unclassified EC3.1.3.16 B. WH2Unclassified EC3.1.6.6 B. WH2Unknown Unknown B. WH2

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Transporters;ABC transpNOT DEFINED C. scindensAmino sugar and nucleoEC3.2.1.55 B. thetaiotaomicronGlycolysis / Gluconeoge EC5.1.3.3 B. uniformisTransporters;ABC transpNOT DEFINED B. vulgatusOxidative phosphorylat EC2.7.4.1 B. vulgatusUnknown Unknown R. obeumTransporters;ABC transpNOT DEFINED C. scindensTransporters;ABC transpNOT DEFINED B. vulgatusTwo-component systemNOT DEFINED B. vulgatusUnknown Unknown B. caccaePyrimidine metabolism; EC2.1.3.2 B. ovatusUnclassified NOT DEFINED B. thetaiotaomicronUnknown Unknown B. WH2Unknown Unknown B. thetaiotaomicronUnclassified NOT DEFINED B. WH2Porphyrin and chloroph EC2.7.1.156;EC2.7.7.62 P. distasonisTransporters;ABC transpNOT DEFINED B. uniformisTransporters NOT DEFINED B. thetaiotaomicronUnknown Unknown B. vulgatusUnclassified NOT DEFINED B. caccaeGlycosyltransferases;Li EC2.-.-.- P. distasonisTwo-component systemNOT DEFINED P. distasonisUnknown Unknown B. vulgatusUnclassified NOT DEFINED B. vulgatusUnknown Unknown B. ovatusChromosome NOT DEFINED B. uniformisTransporters;ABC trans NOT DEFINED B. vulgatusUnclassified EC1.1.1.91 P. distasonisPenicillin and cephalos EC3.5.2.6 P. distasonisTransporters;ABC transpEC3.6.3.27 D. longicatenaUnclassified NOT DEFINED P. distasonisUnknown Unknown B. thetaiotaomicronUnknown Unknown B. WH2Unclassified NOT DEFINED B. uniformisUnknown Unknown B. caccaeTransporters;ABC transpNOT DEFINED B. caccaeChaperones and folding NOT DEFINED R. torquesUnknown Unknown B. WH2Unknown Unknown B. uniformisUnknown Unknown B. vulgatusUnknown Unknown B. uniformisUnknown Unknown P. distasonisTranscription factors NOT DEFINED C. scindensUnclassified EC3.1.21.5 B. vulgatus

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Transporters;ABC trans NOT DEFINED P. distasonisAlanine, aspartate and EC6.3.4.5 B. caccaeUnknown Unknown R. torquesTransporters;ABC trans NOT DEFINED D. longicatenaTransporters;ABC transpEC3.6.3.27 B. uniformisUnclassified NOT DEFINED C. scindensUnclassified NOT DEFINED B. WH2Pentose and glucuronateEC3.2.1.31 B. caccaeSecretion system NOT DEFINED P. distasonisUnknown Unknown B. ovatusUnclassified NOT DEFINED C. scindensUnclassified NOT DEFINED B. caccaeUnknown Unknown R. torquesUnclassified NOT DEFINED C. scindensUnknown Unknown B. WH2Transcription factors NOT DEFINED C. scindensUnknown Unknown C. scindensUnclassified NOT DEFINED B. ovatusTerpenoid backbone bioEC2.7.7.60 P. distasonisUnknown Unknown C. scindensUnknown Unknown B. caccaeArginine and proline meEC1.2.1.41 P. distasonisUnknown Unknown B. caccaeUnclassified EC3.4.11.- B. ovatusUnknown Unknown B. vulgatusArginine and proline meEC3.4.11.5 C. scindensUnclassified NOT DEFINED P. distasonisUnknown Unknown B. uniformisPurine metabolism EC3.6.1.11 B. vulgatusUnknown Unknown B. uniformisUnclassified EC2.7.7.- P. distasonisUnknown Unknown B. thetaiotaomicronUnknown Unknown B. WH2Benzoate degradation viEC4.1.1.44 R. obeumLipopolysaccharide bios NOT DEFINED B. thetaiotaomicronUnknown Unknown B. ovatusTransporters;ABC transpNOT DEFINED C. aerofaciensUnknown Unknown B. WH2Unknown Unknown R. torquesUnknown Unknown B. ovatusUnknown Unknown B. thetaiotaomicronUnclassified EC3.2.-.- B. ovatusTransporters;ABC trans NOT DEFINED R. obeumTranscription factors NOT DEFINED B. vulgatus

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Unknown Unknown C. aerofaciensUnclassified EC1.97.1.4 C. scindensUnknown Unknown B. ovatusUnknown Unknown B. ovatusUnclassified NOT DEFINED B. thetaiotaomicronUnknown Unknown B. ovatusUnknown Unknown B. ovatusUnclassified EC3.2.1.8 B. ovatusUnknown Unknown B. ovatusUnknown Unknown B. thetaiotaomicronUnknown Unknown B. WH2Unknown Unknown B. ovatusUnclassified EC3.4.21.- B. ovatusUnknown Unknown B. thetaiotaomicronOther glycan degradatioEC3.2.1.51 B. ovatusUnknown Unknown B. ovatusUnclassified NOT DEFINED B. thetaiotaomicronChaperones and folding NOT DEFINED B. ovatusGlycine, serine and thr EC2.3.1.29 P. distasonisPentose and glucuronateEC5.3.1.4 B. thetaiotaomicronUnknown Unknown B. thetaiotaomicronRibosome NOT DEFINED B. thetaiotaomicronPentose phosphate pathwEC2.2.1.1 B. thetaiotaomicronUnknown Unknown B. ovatusUnknown Unknown B. ovatusPentose and glucuronateEC2.7.1.16 B. thetaiotaomicronUnknown Unknown B. ovatusHomologous recombinatiNOT DEFINED B. thetaiotaomicronUnclassified EC3.2.1.8 B. ovatusUnknown Unknown B. ovatusUnclassified NOT DEFINED B. thetaiotaomicronUnknown Unknown B. WH2Unknown Unknown B. ovatusUnknown Unknown C. scindensPurine metabolism;Pyri EC3.1.4.16|EC3.1.3.6 P. distasonisUnknown Unknown B. thetaiotaomicronUnknown Unknown B. thetaiotaomicronUnknown Unknown B. thetaiotaomicronUnknown Unknown B. thetaiotaomicronStarch and sucrose metaEC2.7.1.69|NOT DEFINED C. aerofaciensUnknown Unknown B. WH2Unknown Unknown B. thetaiotaomicronUnknown Unknown B. uniformisAmino sugar and nucleoEC3.2.1.55 B. ovatus

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Unknown Unknown P. distasonisUnknown Unknown P. distasonisUnclassified NOT DEFINED B. WH2Unclassified EC3.2.1.139 B. ovatusRibosome NOT DEFINED B. thetaiotaomicronUnclassified EC3.6.1.- B. thetaiotaomicronUnknown Unknown P. distasonisUnclassified EC1.8.1.8 B. ovatusUnknown Unknown B. WH2Unknown Unknown B. caccaeUnclassified EC3.4.21.- B. thetaiotaomicronUnclassified NOT DEFINED B. ovatusUnknown Unknown B. thetaiotaomicronUnknown Unknown B. ovatusUnknown Unknown B. thetaiotaomicronFructose and mannose mEC2.7.7.13 B. thetaiotaomicronFructose and mannose mEC2.7.1.4 B. vulgatusComplement and coagulaNOT DEFINED B. ovatusUnknown Unknown B. WH2Phosphonate and phospEC4.1.1.82 B. uniformisAscorbate and aldarate EC5.1.3.4 B. thetaiotaomicronUnknown Unknown B. thetaiotaomicronUnclassified NOT DEFINED B. thetaiotaomicronTransporters NOT DEFINED B. vulgatusRibosome NOT DEFINED B. thetaiotaomicronUnknown Unknown P. distasonisGalactose metabolism;AEC5.1.3.2 B. uniformisUnknown Unknown B. WH2Unknown Unknown B. vulgatusUnknown Unknown B. thetaiotaomicronUnknown Unknown B. thetaiotaomicronUnclassified NOT DEFINED B. thetaiotaomicronPyrimidine metabolism EC2.7.4.14 D. longicatenaUnknown Unknown B. ovatusUnclassified NOT DEFINED B. vulgatusUnclassified EC2.-.-.- B. uniformisUnknown Unknown C. scindensUnknown Unknown P. distasonisUnknown Unknown B. WH2Two-component systemNOT DEFINED B. WH2Amino sugar and nucleoEC2.7.7.43 B. uniformisUnknown Unknown B. ovatusUnknown Unknown B. ovatusBiotin metabolism;TranscEC6.3.4.15 B. thetaiotaomicron

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Unknown Unknown B. vulgatusUnknown Unknown P. distasonisUnknown Unknown B. WH2Unknown Unknown B. WH2Unknown Unknown B. uniformisUnknown Unknown B. thetaiotaomicronUnknown Unknown B. caccaeUnknown Unknown C. scindensUnknown Unknown B. vulgatusUnknown Unknown B. vulgatusUnknown Unknown P. distasonisTranscription factors NOT DEFINED B. WH2Unknown Unknown B. ovatusStarch and sucrose met EC3.2.1.65 B. vulgatusUnknown Unknown B. thetaiotaomicronUnclassified EC2.6.1.- B. uniformisUnknown Unknown B. ovatusAmino sugar and nucleoEC3.2.1.55 B. thetaiotaomicronUnknown Unknown B. thetaiotaomicronUnknown Unknown C. scindensAmino sugar and nucleoEC2.5.1.56 B. uniformisFolate biosynthesis EC3.5.4.16 B. vulgatusInositol phosphate met EC4.2.1.44 D. longicatenaUnknown Unknown B. thetaiotaomicronUnknown Unknown B. WH2Unknown Unknown B. WH2Unknown Unknown C. aerofaciensPyruvate metabolism EC4.2.3.3 B. vulgatusUnclassified EC1.3.1.74 P. distasonisUnclassified EC3.2.1.- B. thetaiotaomicronInositol phosphate metaEC1.1.1.18 D. longicatenaUnknown Unknown B. uniformisGalactose metabolism;AEC5.1.3.2 B. WH2Unknown Unknown B. thetaiotaomicronUnknown Unknown B. WH2Unknown Unknown B. WH2Amino sugar and nucleotEC1.1.1.- B. WH2RNA polymerase NOT DEFINED P. distasonisDNA replication;DNA repEC2.7.7.- C. aerofaciensUnknown Unknown P. distasonisUnknown Unknown B. WH2Unknown Unknown R. obeumTransporters;ABC transpNOT DEFINED D. longicatenaUnknown Unknown B. thetaiotaomicron

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Fructose and mannose mEC1.1.1.-|EC4.2.1.- B. uniformisUnknown Unknown P. distasonisUnknown Unknown B. WH2Unknown Unknown B. WH2Peptidases EC3.4.13.- R. obeumUnknown Unknown R. torquesUnclassified NOT DEFINED D. longicatenaUnclassified EC2.8.3.- C. scindensGalactose metabolism;SEC3.2.1.26 C. aerofaciensUnclassified EC3.1.1.6 B. thetaiotaomicronUnclassified EC2.7.3.- B. ovatusRibosome NOT DEFINED B. thetaiotaomicronUnknown Unknown B. uniformisUnknown Unknown C. aerofaciensUnclassified NOT DEFINED D. longicatenaUnknown Unknown B. caccaeFructose and mannose EC2.4.1.- B. caccaeUnknown Unknown B. caccaeFructose and mannose mEC4.2.1.47 B. WH2Folate biosynthesis EC1.12.98.1 B. WH2Unknown Unknown B. WH2Unclassified EC2.6.1.- B. uniformisUnknown Unknown B. uniformisUnknown Unknown B. WH2Amino sugar and nucleoEC5.4.2.10 C. aerofaciensLipopolysaccharide bios EC2.4.1.- B. WH2Unknown Unknown B. WH2Unclassified EC2.3.1.28 B. WH2Unknown Unknown B. WH2Unknown Unknown B. thetaiotaomicronUnknown Unknown B. uniformisUnknown Unknown C. aerofaciensUnknown Unknown P. distasonisFructose and mannose EC2.4.1.- B. WH2Bacterial toxins;NOD-lik NOT DEFINED P. distasonisFatty acid biosynthesis; EC3.1.2.14 B. caccaeUnknown Unknown R. obeumUnknown Unknown C. scindensRibosome NOT DEFINED C. aerofaciensGlycerophospholipid meEC2.7.7.15 B. uniformisFructose and mannose mEC1.1.1.-|EC4.2.1.- P. distasonisUnknown Unknown P. distasonisMethane metabolism EC3.1.2.12 B. thetaiotaomicronUnclassified EC3.5.1.28 B. uniformis

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Nucleotide excision rep EC3.6.1.- C. scindensTranscription factors NOT DEFINED C. aerofaciensUnknown Unknown B. uniformisUnknown Unknown C. aerofaciensUnknown Unknown B. uniformisFructose and mannose EC2.4.1.- P. distasonisPorphyrin and chloroph EC1.2.1.70 R. obeumUnknown Unknown B. WH2Biotin metabolism EC2.8.1.6 C. scindensFructose and mannose EC2.4.1.- B. WH2Unknown Unknown B. WH2Unknown Unknown B. thetaiotaomicronUnclassified NOT DEFINED B. uniformisUnknown Unknown B. WH2Unclassified EC3.1.21.4 B. thetaiotaomicronChromosome NOT DEFINED R. obeumUnknown Unknown B. WH2Unclassified NOT DEFINED B. WH2Unknown Unknown B. WH2Amino sugar and nucleotEC1.1.1.158 B. WH2Unknown Unknown B. WH2Transporters NOT DEFINED C. scindensUnknown Unknown B. WH2Unclassified NOT DEFINED P. distasonisUnclassified EC2.6.1.- C. aerofaciensUnknown Unknown C. scindensTranscription factors NOT DEFINED C. aerofaciensUnknown Unknown C. aerofaciensUnclassified NOT DEFINED B. thetaiotaomicronUnknown Unknown B. ovatusUnknown Unknown P. distasonisUnclassified EC2.7.8.- B. uniformisUnknown Unknown B. WH2Unclassified NOT DEFINED C. aerofaciensFatty acid biosynthesis; EC1.1.1.100 P. distasonisAminoacyl-tRNA biosyntEC6.1.1.3 R. obeumFructose and mannose EC2.4.1.- B. WH2Unknown Unknown C. scindensUnclassified NOT DEFINED B. WH2Glyoxylate and dicarbox EC3.1.3.18 B. vulgatusUnknown Unknown B. WH2Unknown Unknown B. thetaiotaomicronUnclassified EC3.1.21.- B. vulgatusUnclassified EC2.7.7.49 B. thetaiotaomicron

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Pyrimidine metabolism; EC2.1.3.2 R. obeumTwo-component systemNOT DEFINED R. torquesUnknown Unknown B. WH2Unknown Unknown R. obeumUnknown Unknown C. aerofaciensPyrimidine metabolism; EC6.3.5.5 B. uniformisUnknown Unknown C. scindensUnknown Unknown C. scindensUnknown Unknown B. thetaiotaomicronUnclassified EC3.6.3.- C. aerofaciensUnknown Unknown C. aerofaciensTransporters;ABC transpEC3.6.3.17 D. longicatenaUnknown Unknown B. uniformisFructose and mannose EC2.4.1.- B. WH2Unclassified NOT DEFINED C. aerofaciensUnknown Unknown C. aerofaciensTransporters;PhosphotraEC2.7.1.69|EC2.7.1.69|NOT DEFINED D. longicatenaUnknown Unknown P. distasonisUnclassified NOT DEFINED B. WH2Mismatch repair;DNA reNOT DEFINED C. aerofaciensUnknown Unknown B. ovatusUnknown Unknown B. ovatusUnknown Unknown B. WH2Unknown Unknown B. vulgatusUnknown Unknown B. ovatusUnknown Unknown B. ovatusUnclassified NOT DEFINED C. scindensUnknown Unknown B. ovatusUnknown Unknown B. vulgatusUnknown Unknown B. caccaeUnknown Unknown C. scindensUnknown Unknown C. scindensPeptidoglycan biosyntheEC3.4.16.4 C. scindensUnknown Unknown B. vulgatusUnclassified NOT DEFINED C. scindensPeptidases;Protein expoEC3.4.21.89 C. scindensUnknown Unknown B. WH2Transcription factors NOT DEFINED C. scindensAmino sugar and nucleoEC4.2.1.45 B. vulgatusUnknown Unknown C. scindensUnclassified NOT DEFINED C. scindensUnclassified NOT DEFINED C. scindensUnclassified EC3.1.1.53 B. ovatusUnknown Unknown C. scindens

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Unknown Unknown C. scindensUnknown Unknown B. caccaeUnknown Unknown B. uniformisUnknown Unknown B. ovatusUnknown Unknown C. scindensUnknown Unknown C. scindensUnclassified EC3.5.1.- C. scindensUnknown Unknown C. scindensProtein kinases;Two-co EC2.7.13.3 B. uniformisAmino sugar and nucleotEC5.1.3.14 B. uniformisUnknown Unknown B. ovatusUnclassified EC3.2.1.40 B. uniformisUnclassified EC3.6.1.- B. vulgatusButanoate metabolism;LEC4.2.1.- B. vulgatusUnknown Unknown C. scindensUnknown Unknown B. WH2Unknown Unknown B. ovatusAmino sugar and nucleotEC5.1.3.14 B. vulgatusAmino sugar and nucleotEC5.1.3.14 B. vulgatusUnknown Unknown B. vulgatusUnknown Unknown C. scindensUnknown Unknown B. ovatusSecretion system NOT DEFINED C. scindensUnclassified EC3.1.1.53 B. ovatusRNA polymerase NOT DEFINED C. scindensUnknown Unknown B. ovatusUnknown Unknown B. WH2Peptidases EC3.4.21.102 B. vulgatusUnclassified NOT DEFINED C. scindensUnclassified NOT DEFINED B. ovatusUnknown Unknown B. ovatusUnknown Unknown B. WH2Unknown Unknown B. uniformisUnknown Unknown B. uniformisUnclassified NOT DEFINED C. scindensUnknown Unknown B. ovatusUnknown Unknown B. WH2Unknown Unknown C. scindensUnclassified NOT DEFINED B. caccaeUnknown Unknown B. uniformisUnclassified NOT DEFINED C. scindensUnknown Unknown B. vulgatusRNA polymerase NOT DEFINED C. scindensUnclassified NOT DEFINED C. scindens

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Unknown Unknown B. ovatusUnknown Unknown B. uniformisUnknown Unknown B. thetaiotaomicronUnclassified EC3.1.3.16 C. scindensUnknown Unknown B. uniformisPeptidases NOT DEFINED C. scindensUnknown Unknown B. vulgatusUnknown Unknown C. scindensUnknown Unknown C. scindensPeptidases EC3.4.24.64 B. uniformisAmino sugar and nucleoEC3.2.1.55 B. uniformisUnknown Unknown C. scindensAtrazine degradation EC3.5.4.- C. scindensTransporters;ABC transpNOT DEFINED R. obeumUnknown Unknown C. scindensUnknown Unknown C. scindensOther glycan degradatioEC3.2.1.96 B. ovatusUnclassified NOT DEFINED C. scindensOther glycan degradatioEC3.2.1.51 B. vulgatusUnknown Unknown B. vulgatusUnknown Unknown C. scindensTransporters NOT DEFINED B. ovatusUnclassified NOT DEFINED C. scindensUnclassified EC3.6.1.- B. vulgatusUnclassified EC3.6.1.- B. vulgatusTranscription factors NOT DEFINED C. scindensUnknown Unknown B. WH2Chromosome NOT DEFINED C. scindensSecretion system NOT DEFINED B. ovatusSecretion system;BacteriNOT DEFINED C. scindensUnknown Unknown B. uniformisUnknown Unknown C. scindensUnclassified NOT DEFINED C. scindensUnknown Unknown B. thetaiotaomicronUnknown Unknown B. vulgatusUnclassified NOT DEFINED B. uniformisUnclassified EC3.5.1.28 R. torquesUnknown Unknown B. ovatusUnknown Unknown B. ovatusUnknown Unknown C. scindensChromosome EC3.5.1.28 C. scindensUnclassified NOT DEFINED C. scindensUnknown Unknown C. scindensGlycolysis / Gluconeoge EC5.1.3.3 B. uniformis

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Unclassified NOT DEFINED B. WH2Unclassified NOT DEFINED C. scindensTwo-component systemNOT DEFINED B. uniformisUnknown Unknown B. vulgatusAmino sugar and nucleotEC3.2.1.52 B. ovatusUnknown Unknown B. uniformisUnknown Unknown C. scindensChromosome EC3.5.1.28 C. scindensTranscription factors NOT DEFINED C. scindensTransporters;ABC transpNOT DEFINED C. scindensUnknown Unknown B. ovatusUnclassified NOT DEFINED C. scindensUnclassified NOT DEFINED C. scindensAmino sugar and nucleoEC5.1.3.8 B. ovatusGalactose metabolism;SEC3.2.1.23 B. WH2Unknown Unknown B. ovatusUnknown Unknown B. ovatusUnknown Unknown C. scindensUnknown Unknown C. scindensTransporters;ABC transpNOT DEFINED C. scindensUnclassified NOT DEFINED C. scindensUnknown Unknown B. ovatusGalactose metabolism;AEC5.1.3.2 B. caccaeTwo-component systemNOT DEFINED B. vulgatusTwo-component systemNOT DEFINED B. vulgatusUnknown Unknown B. uniformisUnknown Unknown B. WH2Unknown Unknown B. uniformisUnknown Unknown C. scindensUnknown Unknown B. vulgatusUnknown Unknown C. scindensUnknown Unknown P. distasonisUnknown Unknown C. scindensUnknown Unknown C. scindensUnclassified EC2.7.3.- B. ovatusTransporters;ABC transpNOT DEFINED C. scindensTwo-component systemNOT DEFINED B. uniformisUnclassified EC3.5.1.28 C. scindensTransporters NOT DEFINED R. obeumUnknown Unknown B. ovatusGalactose metabolism;SEC3.2.1.23 B. uniformisUnknown Unknown B. WH2Unknown Unknown B. ovatusPeroxisome;Amyotrophic lEC1.15.1.1 C. scindens

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Terpenoid backbone bioEC2.7.1.148 C. scindensPurine metabolism;Pyri EC1.17.4.2 B. caccaeTransporters;ABC transpNOT DEFINED C. scindensUnclassified EC3.5.-.- C. scindensUnclassified EC2.7.11.1 C. scindensStarch and sucrose metaEC2.4.1.1 R. obeumUnknown Unknown C. scindensUnknown Unknown B. uniformisRibosome NOT DEFINED B. uniformisUnknown Unknown B. uniformisTerpenoid backbone bioEC2.5.1.- B. uniformisTranscription factors NOT DEFINED B. caccaeTransporters;ABC transpNOT DEFINED C. aerofaciensButanoate metabolism;LEC4.2.1.- B. uniformisDNA replication;DNA re NOT DEFINED C. scindensUnknown Unknown B. uniformisUnknown Unknown C. scindensTwo-component systemNOT DEFINED B. vulgatusUnknown Unknown B. uniformisUnknown Unknown C. scindensUnknown Unknown B. uniformisUnknown Unknown B. ovatusUnknown Unknown B. thetaiotaomicronNitrogen metabolism;Al EC6.3.1.2 B. uniformisUnclassified EC3.6.1.- B. uniformisUnknown Unknown B. uniformisUnknown Unknown C. scindensUnknown Unknown B. caccaeAmino sugar and nucleoEC2.7.7.43 B. vulgatusUnknown Unknown B. uniformisUnknown Unknown B. WH2Unknown Unknown P. distasonisPhenylalanine metabolisEC4.1.3.39 B. vulgatusTransporters NOT DEFINED B. ovatusUnknown Unknown B. vulgatusUnknown Unknown B. ovatusUnclassified EC3.6.1.- B. ovatusUnknown Unknown B. uniformisUnclassified NOT DEFINED C. scindensUnclassified NOT DEFINED B. vulgatusUnknown Unknown B. vulgatusUnknown Unknown R. obeumUnknown Unknown B. uniformisUnknown Unknown B. WH2

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RNA polymerase NOT DEFINED C. scindensTwo-component systemNOT DEFINED C. scindensUnknown Unknown C. scindensUnknown Unknown B. ovatusUnknown Unknown C. scindensDNA replication protein EC2.1.1.72 B. uniformisUnclassified NOT DEFINED B. vulgatusUnknown Unknown B. ovatusUnclassified NOT DEFINED C. scindensUnclassified NOT DEFINED C. scindensUnknown Unknown B. vulgatusUnclassified NOT DEFINED C. scindensUnclassified NOT DEFINED C. scindensUnclassified NOT DEFINED B. ovatusGalactose metabolism;AEC5.1.3.2 B. uniformisUnknown Unknown B. uniformisUnknown Unknown P. distasonisUnknown Unknown B. uniformisPentose and glucuronateEC4.2.1.7 B. uniformisUnknown Unknown B. caccaeUnclassified NOT DEFINED C. scindensUnknown Unknown B. ovatusUnknown Unknown B. ovatusPyrimidine metabolism; EC2.1.3.2 B. ovatusAmino sugar and nucleoEC5.1.3.9 C. scindensAmino sugar and nucleotEC5.1.3.14 B. uniformisUnclassified NOT DEFINED C. spiroformeUnclassified NOT DEFINED R. torquesPeptidoglycan biosyntheEC3.4.16.4 C. scindensUnknown Unknown B. vulgatusChaperones and folding NOT DEFINED B. uniformisSecretion system NOT DEFINED C. scindensGlycosaminoglycan deg EC2.3.1.78 B. uniformisUnclassified EC3.2.1.99 B. uniformisUnknown Unknown C. scindensUnknown Unknown C. scindensUnknown Unknown C. scindensSteroid hormone biosyntEC1.3.99.5 B. caccaeUnclassified EC2.6.1.- B. uniformisUnknown Unknown B. WH2Amino sugar and nucleotEC1.1.1.158 C. scindensFructose and mannose mEC4.2.1.47 B. uniformisUnknown Unknown B. vulgatusUnknown Unknown C. scindens

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Amino sugar and nucleoEC2.5.1.56 B. vulgatusUnknown Unknown B. uniformisHistidine metabolism;T EC2.1.1.- B. uniformisUnknown Unknown B. uniformisUnclassified NOT DEFINED B. uniformisTransporters NOT DEFINED P. distasonisUnclassified NOT DEFINED B. vulgatusUnknown Unknown C. scindensUnclassified EC2.7.10.- B. uniformisUnclassified NOT DEFINED C. scindensUnknown Unknown B. vulgatusRibosome NOT DEFINED B. caccaeUnknown Unknown B. ovatusUnknown Unknown B. uniformisAmino sugar and nucleotEC5.1.3.14 B. vulgatusUnclassified EC3.2.1.- B. caccaeUnknown Unknown B. caccaeTransporters;ABC transpNOT DEFINED B. vulgatusAmino sugar and nucleotEC5.1.3.14 B. uniformisUnclassified NOT DEFINED B. uniformisUnknown Unknown B. ovatusUnclassified NOT DEFINED C. scindensPeptidases;Cellular anti EC3.4.14.5 B. ovatusLysine biosynthesis EC5.1.1.7 P. distasonisUnknown Unknown B. WH2Unknown Unknown C. scindensAmino sugar and nucleoEC5.1.3.8 B. ovatusUnknown Unknown B. ovatusGlycolysis / Gluconeog EC2.7.1.11 B. uniformisUnclassified EC1.11.1.15 B. ovatusStarch and sucrose met EC2.7.7.33 B. vulgatusGlycolysis / Gluconeoge EC5.1.3.3 B. WH2Unknown Unknown B. ovatusUnknown Unknown P. distasonisTransporters NOT DEFINED R. obeumUnknown Unknown B. ovatusUnknown Unknown B. caccaePentose and glucuronat EC1.1.1.22 P. distasonisGalactose metabolism;SEC3.2.1.23 P. distasonisUnclassified NOT DEFINED C. scindensUnknown Unknown B. uniformisGlycosyltransferases EC2.4.1.- B. uniformisUnknown Unknown C. scindensTransporters;Meiosis - yNOT DEFINED B. uniformis

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Inositol phosphate metaEC3.1.4.3 B. thetaiotaomicronUnknown Unknown B. uniformisUnknown Unknown B. uniformisGlycerophospholipid meEC3.1.4.46 B. WH2Unclassified NOT DEFINED C. scindensUnknown Unknown R. torquesTransporters NOT DEFINED R. obeumRNA polymerase NOT DEFINED B. caccaeUnknown Unknown B. uniformisUnclassified NOT DEFINED P. distasonisRibosome NOT DEFINED B. caccaeUnclassified NOT DEFINED P. distasonisPyrimidine metabolism; EC6.3.5.5 B. vulgatusTranscription factors NOT DEFINED R. obeumUnknown Unknown B. uniformisOther glycan degradatioEC3.2.1.51 B. uniformisGlyoxylate and dicarbox EC2.7.1.31 R. torquesUnclassified NOT DEFINED B. uniformisUnknown Unknown B. ovatusOxidative phosphorylati EC1.6.5.3 B. uniformisFructose and mannose mEC1.1.1.- B. uniformisUnclassified NOT DEFINED C. scindensUnclassified NOT DEFINED B. uniformisUnknown Unknown R. obeumUnknown Unknown P. distasonisUnknown Unknown B. uniformisUnknown Unknown P. distasonisPyrimidine metabolism;OEC2.1.1.45 C. scindensUnknown Unknown B. ovatusUnknown Unknown B. uniformisUnknown Unknown B. ovatusUnknown Unknown B. caccaeUnclassified EC3.2.1.40 B. uniformisUnknown Unknown B. ovatusUnclassified NOT DEFINED C. scindensUnknown Unknown P. distasonisUnknown Unknown B. uniformisUnknown Unknown B. uniformisUnknown Unknown R. obeumRNA polymerase NOT DEFINED B. ovatusUnknown Unknown B. vulgatusGlyoxylate and dicarbo EC1.12.7.2 C. scindensUnknown Unknown C. scindensUnknown Unknown C. scindens

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Unknown Unknown C. scindensUnknown Unknown P. distasonisLipopolysaccharide bios EC2.7.8.- P. distasonisUnknown Unknown R. torquesUnknown Unknown B. thetaiotaomicronFructose and mannose EC2.4.1.- B. vulgatusUnknown Unknown C. scindensUnclassified NOT DEFINED C. scindensUnknown Unknown C. scindensUnknown Unknown C. scindensUnknown Unknown B. ovatusUnknown Unknown B. thetaiotaomicronUnclassified NOT DEFINED B. ovatusUnknown Unknown R. obeumRNA polymerase NOT DEFINED B. uniformisUnclassified EC2.5.1.- B. thetaiotaomicronUnclassified EC3.2.1.99 B. uniformisGalactose metabolism;SEC3.2.1.23 B. uniformisPorphyrin and chloroph EC6.3.5.9;EC6.3.1.- R. torquesLipopolysaccharide bios NOT DEFINED P. distasonisUnknown Unknown B. caccaeUnknown Unknown B. ovatusUnknown Unknown C. scindensUnknown Unknown C. scindensUnclassified NOT DEFINED B. thetaiotaomicronTerpenoid backbone bioEC2.7.1.148 B. uniformisUnknown Unknown C. scindensUnknown Unknown R. obeumTransporters;ABC transpNOT DEFINED P. distasonisUnknown Unknown B. uniformisUnknown Unknown C. scindensUnclassified NOT DEFINED B. vulgatusUnknown Unknown B. caccaeGlycolysis / Gluconeoge EC5.4.2.1 B. vulgatusUnclassified NOT DEFINED B. vulgatusUnclassified NOT DEFINED B. uniformisFructose and mannose mEC1.1.1.271 B. uniformisLipopolysaccharide bios NOT DEFINED B. vulgatusUnknown Unknown B. uniformisGlycosaminoglycan deg EC2.3.1.78 B. WH2Unclassified NOT DEFINED P. distasonisLysine biosynthesis EC5.1.1.7 B. vulgatusThiamine metabolism EC2.5.1.3 B. uniformisPhenylalanine, tyrosine EC4.1.3.27 P. distasonis

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Unknown Unknown B. ovatusUnknown Unknown B. vulgatusSteroid hormone biosyntEC3.1.6.1 B. uniformisUnknown Unknown P. distasonis

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ComparisonEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4x

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Early Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4x

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Early Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4xEarly Up ≥ 4x

Early Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4x

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Early Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4x

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Early Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4x

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Early Down ≥ 4xEarly Down ≥ 4xEarly Down ≥ 4x

Late Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4x

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Late Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4x

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Late Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4x

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Late Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4x

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Late Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4x

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Late Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4xLate Up ≥ 4x

Late Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4x

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Late Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4x

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Late Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4x

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Late Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4x

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Late Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4x

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Late Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4x

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Late Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4x

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Late Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4x

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Late Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4x

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Late Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4xLate Down ≥ 4x

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Table S11. Gene expression profile features with predictive value for classifying mouse fecal samples by treatment status (i.e. pre- versus post-treatment with the FMP consortium).

A. 'Predictive' and 'highly predictive' KEGG categories.

KEGG category Importance scoreGermination 0.0535741544Sporulation 0.0481584029Cell motility and secretion 0.0303306987Function unknown 0.0208305913Amino acid metabolism 0.0143044135Lipid metabolism 0.007210555Metabolism of other amino acids 0.0067224553Carbohydrate metabolism 0.0062805806Environmental adaptation 0.0030928005Cell growth and death 0.0027502856Pores ion channels 0.0023553748Translation 0.002096304Transcription related proteins 0.0020617993Transport and catabolism 0.0019053763Signaling Molecules and interaction 0.0018589125Transcription 0.0014815087

B. 'Predictive' and 'highly predictive' KEGG pathways.

KEGG pathway Importance scoreAtrazine degradation 0.0231Novobiocin biosynthesis 0.0197Isoquinoline alkaloid biosynthesis 0.0161Pentose and glucuronate interconversions 0.0119Fatty acid metabolism 0.0080Fructose and mannose metabolism 0.0072Alanine aspartate and glutamate metabolism 0.0072beta-Alanine metabolism 0.0062Nitrogen metabolism 0.0060Inositol phosphate metabolism 0.0059Arachidonic acid metabolism 0.0057Carbazole degradation 0.0054Taurine and hypotaurine metabolism 0.0053Steroid hormone biosynthesis 0.0045Sphingolipid metabolism 0.0044

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Phenylalanine metabolism 0.0037Pyruvate metabolism 0.0036Prion diseases 0.0034Carbon fixation in photosynthetic organisms 0.0032Streptomycin biosynthesis 0.0029Arginine and proline metabolism 0.0024Starch and sucrose metabolism 0.0023Other glycan degradation 0.0022Flavone and flavonol biosynthesis 0.0020Alzheimers disease 0.0015Selenoamino acid metabolism 0.0014Styrene degradation 0.0013Translation factors 0.0013Sulfur metabolism 0.0013Lysosome 0.0012Benzoate degradation via hydroxylation 0.0011

C. 'Predictive' and 'highly predictive' enzyme commission (EC) numbers.

Enzyme commission (EC) number Importance scoretRNA-specific adenosine deaminase [EC:3.5.4.-] 0.0095282518malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1 0.0084877903fructoselysine 6-phosphate deglycase [EC:3.5.-.-] 0.008074793aspartate aminotransferase [EC:2.6.1.1] 0.0070707214L-rhamnose isomerase [EC:5.3.1.14] 0.0055624808xylose isomerase [EC:5.3.1.5] 0.0048877269endoribonuclease Dicer [EC:3.1.26.-] 0.0032801509pectinesterase [EC:3.1.1.11] 0.0032608174feruloyl-CoA synthase [EC:6.2.1.34] 0.0031507445inosose dehydratase [EC:4.2.1.44] 0.0025155106GDPmannose 4,6-dehydratase [EC:4.2.1.47] 0.0022753751diaminopimelate dehydrogenase [EC:1.4.1.16] 0.002246208foldase protein PrsA [EC:5.2.1.8] 0.0020093654sialidase-1 [EC:3.2.1.18] 0.0017006891arabinogalactan endo-1,4-beta-galactosidase [EC:3.2.1.89] 0.001672472alanine dehydrogenase [EC:1.4.1.1] 0.0016721222',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16] 0.0016477696threonyl-tRNA synthetase [EC:6.1.1.3] 0.0016394466transcriptional repressor NF-X1 [EC:6.3.2.-] 0.0015574772histidinol-phosphate aminotransferase [EC:2.6.1.9] 0.0015560152

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4-hydroxyphenylacetate-3-hydroxylase large chain [EC:1.14.13.3] 0.001490383GTP cyclohydrolase II [EC:3.5.4.25] 0.0014537865site-specific DNA-methyltransferase (cytosine-N4-specific) [EC:2.1.1.113 0.0013531933GTP cyclohydrolase II [EC:3.5.4.25] 0.0013374559leucyl-tRNA synthetase [EC:6.1.1.4] 0.0013198168peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11] 0.0013152166rubredoxin-NAD+ reductase [EC:1.18.1.1] 0.00128778433-oxo-5-alpha-steroid 4-dehydrogenase 3 [EC:1.3.99.5] 0.00124514124-hydroxy 2-oxovalerate aldolase [EC:4.1.3.39] 0.0012408945transcriptional activator TenA [EC:3.5.99.2] 0.0012273392choline-sulfatase [EC:3.1.6.6] 0.0011849419threonine 3-dehydrogenase [EC:1.1.1.103] 0.0011623461lysostaphin [EC:3.4.24.75] 0.0011288361formyltetrahydrofolate deformylase [EC:3.5.1.10] 0.0010642359cyclase HisF [EC:4.1.3.-] 0.0010215968

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Table S11. Gene expression profile features with predictive value for classifying mouse fecal samples by treatment status (i.e. pre- versus post-treatment with the FMP consortium).

Highly predictivePredictive

Highly predictivePredictive

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Predictive

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Table S12. Urine metabolites whose levels change significantly in transitions between colonization states.

p-value (Tukey's HDS)

Name PubChem CID KEGG Day 0 Day 14 Day 42 0 vs 14 0 vs 42 14 vs 42 0 vs 14 0 vs 42Oxalic acid 971 C00209 7.863 76.9 19.37 21.11 19.89 3.03E-02 4.83E-01 9.08E-02

94309 N/A 9.425 74.5 23.91 18.70 19.54 2.57E-02 5.81E-03 6.83E-01Ethanolamine 700 C00189 9.799 83.6 22.12 20.64 20.46 2.65E-02 1.18E-02 7.94E-01Citraconic acid 643798 C02226 10.798 67.8 27.54 23.99 25.92 7.96E-03 9.87E-02 1.33E-01Fumaric acid 444972 C00122 10.973 86.8 17.90 20.65 19.41 1.45E-02 1.54E-01 1.37E-011-Decanol 8174 C01633 11.310 73.8 14.51 22.04 21.79 1.20E-07 2.90E-07 6.93E-01 9.13E-07 1.82E-08Thymine 1135 C00178 11.594 77.1 23.50 20.19 21.21 3.92E-03 1.60E-02 2.65E-01Mesaconic acid 638129 C01732 11.647 93.7 18.04 19.77 20.52 3.67E-03 1.39E-02 3.60E-01

4158 C07196 11.724 71.5 22.55 23.49 23.50 2.40E-02 5.27E-02 9.73E-01Isovalerylglycine 546304 N/A 12.853 90.7 23.12 21.31 22.54 1.68E-02 3.27E-01 1.24E-01Cytosine 597 C00380 13.222 89.5 19.32 16.96 17.85 2.60E-02 5.26E-02 3.09E-01Pyrogallol 1057 C01108 13.422 83.9 17.22 19.00 18.78 2.76E-02 6.89E-03 5.56E-013-Hydroxy-3-methylglutaric acid 1662 C03761 14.144 86.6 22.28 23.77 23.15 1.85E-04 1.81E-02 7.39E-02 3.27E-02 1.65E-035-Aminovaleric acid 138 C00431 14.484 92.2 19.92 21.96 22.44 4.90E-03 1.62E-04 4.11E-01 1.21E-02 4.65E-03Taurine 1123 C00245 14.970 99.8 25.13 27.27 27.46 1.48E-03 2.01E-03 3.71E-01 6.45E-05 5.58E-06Fucose (indistinguishable from 6-deoxyglucose) 17106 C01019 15.459 80.8 25.57 24.12 24.35 1.65E-03 3.65E-03 5.79E-01Putrescine 1045 C00134 15.728 95.3 23.31 21.98 22.06 2.30E-04 1.35E-03 8.16E-01 2.32E-02 2.79E-03Dehydroascorbic acid 835 C05422 16.885 88.7 23.36 22.18 21.30 1.79E-02 9.73E-04 3.28E-02 1.21E-02 4.08E-02Dihydroxyphenyl glycol 91528 C05576 17.182 84.6 21.08 18.66 20.06 1.20E-03 1.81E-01 9.24E-02Vanillylmandelic acid 736172 C05584 17.185 66.4 17.80 19.85 19.27 9.51E-04 1.86E-01 5.84E-01Phenylacetylglycine 68144 C05598 17.352 80.8 21.08 24.19 23.66 1.82E-05 4.01E-04 3.03E-01 2.48E-03 1.16E-043-(4-Hydroxyphenyl)lactic acid 9378 C03672 17.424 91.1 22.58 21.02 21.96 1.66E-02 2.51E-01 1.05E-01Mannose 18950 C00159 17.560 95.0 23.27 22.59 22.83 4.96E-02 2.18E-01 5.56E-018-Aminooctanoic acid 66085 N/A 17.656 65.2 20.51 19.25 19.96 1.01E-04 2.05E-01 1.21E-01

637542 C00811 17.892 68.4 19.87 21.29 21.24 4.98E-03 1.68E-02 9.22E-01Glycylproline 79101 N/A 18.279 87.3 21.31 19.63 19.98 3.14E-03 5.29E-02 5.84E-01Xanthine 1188 C00385 18.596 76.2 20.84 19.74 19.66 4.06E-02 3.66E-03 8.61E-01Cysteinylglycine 65270 C01419 18.937 85.3 18.24 17.24 17.00 1.09E-02 6.13E-04 4.75E-01 2.01E-02 2.77E-03Phytol 5366244 C01389 20.043 65.8 19.97 18.23 N/D 4.16E-02 #DIV/0! #DIV/0!1,4-Dihydroxy-2-naphthoic acid 671 C03657 20.126 76.0 20.84 17.34 17.57 3.53E-04 3.18E-05 6.90E-01 5.96E-05 5.55E-055-Hydroxyindole-3-acetic acid 1826 C05635 20.451 98.8 20.45 19.39 19.24 2.75E-02 1.87E-02 7.80E-013,5-Dimethoxy-4-hydroxycinnamic acid 637775 C00482 20.731 92.1 17.59 21.50 21.61 6.01E-04 2.18E-05 8.72E-01 6.73E-05 2.79E-05Sphingosine 5280335 C00319 22.198 75.4 17.66 15.03 16.77 9.51E-03 2.47E-01 7.15E-025'-Deoxy-5'-(methylthio)adenosine 439176 C00170 25.061 71.3 19.86 18.82 19.16 4.51E-03 8.19E-02 4.16E-01Melibiose (indistinguishable from isomaltose) 440658 C05402 25.522 89.7 20.86 17.81 19.39 3.28E-03 6.25E-03 5.27E-02 7.93E-04 7.46E-02Galactinol 439451 C01235 26.048 74.9 15.51 17.71 19.09 6.85E-03 5.11E-07 4.95E-02 2.93E-03 1.07E-05Daidzein 5281708 C10208 26.092 89.2 16.84 17.92 18.29 4.88E-03 3.90E-04 2.76E-01 1.64E-02 1.03E-034',5,7-Trihydroxyisoflavone 5280961 C06563 26.172 84.3 16.22 17.89 18.34 3.80E-02 1.31E-02 3.71E-01Raffinose (indistinguishable from maltotriose) 439242 C00492 29.135 98.3 26.06 19.85 21.58 7.92E-04 2.70E-06 1.25E-01 9.23E-06 1.90E-04

p-value (Tukey's HDS)

Name PubChem CID KEGG Day 0 Day 14 Day 42 0 vs 14 0 vs 42 14 vs 42 0 vs 14 0 vs 4251 C00026 13.878 97.1 26.06 27.56 26.58 7.52E-02 4.84E-01 0.0161741

Xylose (indistinguishable from lyxose) 135191 C00181 14.735 89.7 22.20 22.62 24.14 4.77E-01 3.27E-03 1.58E-02 0.73438694 0.00507564Orotic acid 967 C00295 15.765 95.8 19.55 17.30 19.95 7.89E-02 7.28E-01 1.07E-02Dehydroascorbic acid 835 C05422 16.885 88.7 23.36 22.18 21.30 1.79E-02 9.73E-04 3.28E-02 0.04082244 0.00037885Fructose 5984 C10906 17.049 91.9 23.88 23.20 24.39 1.89E-01 1.23E-01 4.67E-025-Hydroxylysine 439437 C16742 18.869 75.2 18.95 17.84 19.10 7.67E-02 7.29E-01 4.94E-02

A. Day 0 (germ-free) versus day 14 (colonized with 15-member model community).p-value (Student's t-test)

Retention time (minutes)

Reverse match score

alpha-Methylserine

trans-Cinnamaldehyde

trans-4-Hydroxycinnamic acid

B. Day 14 (colonized with 15-member defined community) versus day 42 (colonized with 15-member community plus five-member FMP consortium).

p-value (Student's t-test)

Retention time (minutes)

Reverse match score

alpha-Ketoglutaric acid

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Xanthosine 1189 C01762 24.061 78.9 18.63 18.99 17.25 6.81E-01 6.05E-02 4.82E-02Galactinol 439451 C01235 26.048 74.9 15.51 17.71 19.09 6.85E-03 5.11E-07 4.95E-02 0.00293299 1.06666E-05

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p-value (Tukey's HDS)

14 vs 42 M1T0 M2T0 M6T0 M8T0 M9T0 M4T14 M5T14 M6T14 M7T14 M8T14 M9T14 M2T42 M3T42 M4T42 M5T42 M6T42 M8T42 M9T42 M10T42 Detected in cecal water?18.8 19.8 19.2 21.1 18.0 21.1 20.8 19.5 22.5 20.8 22.0 18.4 19.8 19.5 22.8 18.9 18.9 21.1 19.7 Y24.0 23.6 23.9 24.2 23.8 17.5 17.3 14.3 15.6 23.5 23.9 24.2 18.8 18.2 19.0 20.5 14.7 17.4 23.6 N22.3 21.9 21.3 22.4 22.7 21.5 21.2 19.4 22.1 20.4 19.3 19.2 22.4 20.4 20.3 18.4 21.3 21.9 19.8 Y27.6 27.6 28.2 26.4 27.9 28.2 23.7 23.0 23.3 22.1 23.6 28.5 27.1 26.7 25.5 27.1 21.9 27.6 23.0 N19.3 15.8 17.8 19.6 17.0 20.2 20.5 22.4 20.6 19.3 20.9 17.4 18.8 18.2 18.2 19.2 19.3 21.1 23.0 Y

1.26E-08 14.7 14.4 15.3 14.3 13.9 23.3 23.0 21.4 21.9 21.1 21.5 21.2 23.0 22.6 19.1 22.0 20.7 21.8 23.9 N24.4 23.9 24.5 21.5 23.2 22.9 21.3 19.0 19.1 19.6 19.2 22.1 21.3 21.8 22.9 22.2 17.9 19.8 21.6 Y18.2 17.7 18.3 18.5 17.5 20.2 21.3 19.0 19.1 19.9 19.2 22.3 21.8 19.7 17.9 19.8 21.6 N22.4 22.2 22.9 23.3 21.9 24.0 24.1 23.3 23.3 22.5 23.8 22.6 24.9 23.3 22.8 23.3 24.0 N23.1 22.5 23.3 23.3 23.3 20.4 23.5 19.9 20.6 21.6 21.8 21.8 24.3 24.4 22.4 21.6 21.0 20.8 23.9 N18.9 21.3 19.0 19.1 18.2 15.7 16.7 16.3 15.0 19.7 18.4 17.2 20.1 19.3 17.2 17.1 17.4 17.1 17.5 Y

17.0 17.4 18.8 19.2 18.9 19.4 18.6 19.1 18.5 20.0 19.8 18.7 17.3 19.6 18.2 18.1 N4.45E-02 22.1 21.8 22.3 22.4 22.8 24.0 24.1 23.5 23.7 23.1 24.2 21.9 24.1 23.2 22.9 23.1 22.5 23.6 24.0 Y4.22E-04 19.8 20.1 19.9 20.0 19.8 22.8 23.4 21.2 22.3 21.6 20.5 21.6 24.4 23.1 22.2 21.7 21.2 22.4 22.9 Y8.55E-07 25.2 25.1 25.3 26.1 23.9 27.4 28.0 27.1 26.6 27.0 27.4 27.5 27.4 27.7 27.3 27.8 27.2 27.2 27.6 Y

25.7 25.4 25.7 25.8 25.2 24.4 25.2 23.6 24.0 23.4 24.0 23.7 25.2 25.4 24.3 23.8 23.7 23.4 25.2 Y2.69E-03 23.5 23.1 22.9 23.5 23.6 21.3 22.1 21.9 22.5 22.2 21.9 22.3 23.5 22.1 22.0 21.4 21.8 22.3 21.1 Y3.79E-04 23.7 22.7 22.5 24.1 23.8 22.7 22.8 21.8 21.8 22.1 21.9 21.7 22.5 21.4 21.3 21.5 20.1 20.0 21.9 N

21.4 21.6 20.1 21.5 20.8 19.8 19.8 17.9 17.6 17.7 19.0 18.4 22.7 22.5 19.0 18.9 17.9 20.8 20.4 N17.8 17.8 20.1 21.1 19.1 19.3 19.5 20.0 17.9 15.1 20.3 20.3 20.9 21.1 N

4.31E-04 21.2 20.7 22.0 21.1 20.4 24.6 24.7 23.9 24.7 23.9 23.3 22.2 24.4 22.4 23.9 23.4 23.4 23.5 26.1 N23.2 22.3 22.1 23.6 21.7 20.1 21.0 20.1 20.6 22.1 22.2 21.5 23.1 23.4 22.0 21.0 20.6 21.4 22.7 N23.2 23.4 22.9 23.8 23.0 22.8 23.2 22.3 22.3 21.7 23.2 22.5 23.9 23.9 22.5 22.8 21.5 22.1 23.4 Y20.9 20.2 20.4 20.4 20.6 18.9 19.0 19.6 19.3 19.5 20.4 20.7 19.8 18.7 20.2 N20.5 19.4 20.1 20.0 19.4 21.1 21.1 20.8 22.0 19.7 23.5 21.8 20.6 20.4 20.7 21.1 22.1 N21.2 20.6 21.0 21.6 22.1 21.0 18.8 19.8 19.9 19.2 19.0 20.0 21.1 21.4 17.8 20.0 19.7 N20.4 20.5 21.0 21.0 21.2 20.6 20.5 19.8 20.2 18.0 19.2 20.1 18.6 20.4 19.7 19.8 19.4 Y

6.98E-01 17.8 18.6 18.2 18.6 17.9 18.0 17.8 17.2 17.5 16.3 16.8 16.4 17.9 17.5 16.5 16.5 16.7 17.4 17.2 N20.5 20.1 19.3 18.2 18.2 N

8.92E-01 21.1 21.1 20.9 19.8 21.3 18.9 16.5 17.7 16.6 17.0 16.8 18.3 18.6 18.4 15.9 17.9 17.2 Y20.0 20.0 20.8 21.0 20.4 20.6 19.9 19.4 18.8 19.3 18.3 18.0 18.8 19.2 20.5 19.4 18.9 18.1 21.0 N

9.79E-01 16.7 17.7 17.8 18.1 21.4 24.4 20.9 21.1 20.5 20.7 21.0 22.5 22.3 21.9 21.3 20.6 21.2 22.2 Y18.1 18.6 18.2 16.1 17.3 13.9 16.4 15.9 12.3 15.4 16.3 17.8 19.2 15.9 17.5 17.1 17.4 15.0 14.2 N20.1 19.8 19.9 20.1 19.4 19.6 19.4 18.3 18.5 18.3 18.8 18.0 20.4 20.1 19.8 18.7 17.9 19.0 19.4 N

4.18E-02 20.8 20.5 21.0 20.9 21.1 19.0 19.0 17.8 16.3 15.8 18.9 18.6 20.7 20.8 19.7 19.8 18.7 19.1 17.6 Y3.29E-02 15.2 15.2 15.8 15.2 16.2 17.7 18.1 17.6 15.6 17.6 19.6 18.7 19.6 20.5 19.5 19.3 18.2 18.6 18.4 N4.63E-01 16.3 17.1 17.0 17.2 16.6 18.0 18.7 17.5 18.3 17.1 17.9 17.8 19.2 18.6 18.5 17.9 17.2 18.2 18.9 Y

16.5 16.9 17.2 14.1 16.3 18.8 18.9 17.7 16.9 16.9 18.3 17.0 19.3 19.1 18.0 18.3 17.3 18.4 19.4 Y1.07E-01 25.6 25.8 26.3 26.0 26.6 20.2 19.2 20.8 17.0 18.4 23.5 20.6 23.1 23.2 21.5 21.7 20.8 21.9 19.8 Y

p-value (Tukey's HDS)

14 vs 42 M1T0 M2T0 M6T0 M8T0 M9T0 M4T14 M5T14 M6T14 M7T14 M8T14 M9T14 M2T42 M3T42 M4T42 M5T42 M6T42 M8T42 M9T42 M10T42 Detected in cecal water?26.8 23.8 26.4 27.5 25.9 27.8 27.7 27.6 27.7 27.0 27.5 25.4 27.4 25.7 26.1 26.9 26.0 27.2 27.8 Y

0.01892621 21.8 21.0 22.8 22.3 23.1 22.4 24.2 22.2 23.2 21.1 22.6 25.0 25.0 24.5 24.7 23.4 23.6 22.6 24.2 Y19.6 19.7 22.5 19.3 16.7 18.0 17.5 16.3 19.7 16.6 15.6 20.3 20.0 22.1 17.1 17.5 20.2 20.7 21.8 N

0.09336359 23.7 22.7 22.5 24.1 23.8 22.7 22.8 21.8 21.8 22.1 21.9 21.7 22.5 21.4 21.3 21.5 20.1 20.0 21.9 N24.2 23.8 23.8 24.2 23.4 23.0 23.7 23.2 21.9 22.3 25.0 23.7 25.0 25.9 24.3 24.3 23.6 23.9 24.4 Y18.9 18.8 19.5 19.6 17.9 19.2 19.3 17.2 16.8 16.9 17.6 18.3 20.1 20.1 19.5 18.7 18.2 18.0 19.9 Y

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16.9 19.2 19.4 19.7 17.9 16.9 19.4 18.0 18.9 19.0 21.7 16.2 17.6 17.3 17.5 16.1 17.0 18.2 18.2 N0.03288776 15.2 15.2 15.8 15.2 16.2 17.7 18.1 17.6 15.6 17.6 19.6 18.7 19.6 20.5 19.5 19.3 18.2 18.6 18.4 N

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Detected in serum?YNYYYNYNNYNNYYNYYYNNNNYNNNYNNNNNNNNNYNY

Detected in serum?YYYYYN

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NN

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Table S13. ShotgunFunctionalizeR analysis of EC-level changes in the metatranscriptome as a function of FMP strain introduction into mice and humans.

EC [Annotation]EC1.-.-.- [NA]EC1.1.-.- [NA]EC1.1.1.- [NA]EC1.1.1.1 [Alcohol dehydrogenase]EC1.1.1.100 [3-oxoacyl-[acyl-carrier-protein] reductase]EC1.1.1.102 [3-dehydrosphinganine reductase]EC1.1.1.103 [L-threonine 3-dehydrogenase]EC1.1.1.122 [D-threo-aldose 1-dehydrogenase]EC1.1.1.125 [2-deoxy-D-gluconate 3-dehydrogenase]EC1.1.1.130 [3-dehydro-L-gulonate 2-dehydrogenase]EC1.1.1.132 [GDP-mannose 6-dehydrogenase]EC1.1.1.133 [dTDP-4-dehydrorhamnose reductase]EC1.1.1.14 [L-iditol 2-dehydrogenase]EC1.1.1.140 [Sorbitol-6-phosphate 2-dehydrogenase]EC1.1.1.154 [Ureidoglycolate dehydrogenase]EC1.1.1.157 [3-hydroxybutyryl-CoA dehydrogenase]EC1.1.1.158 [UDP-N-acetylmuramate dehydrogenase]EC1.1.1.159 [7-alpha-hydroxysteroid dehydrogenase]EC1.1.1.169 [2-dehydropantoate 2-reductase]EC1.1.1.17 [Mannitol-1-phosphate 5-dehydrogenase]EC1.1.1.170 [Sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating)]EC1.1.1.179 [D-xylose 1-dehydrogenase (NADP(+))]EC1.1.1.18 [Inositol 2-dehydrogenase]EC1.1.1.181 [Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase]EC1.1.1.184 [Carbonyl reductase (NADPH)]EC1.1.1.193 [5-amino-6-(5-phosphoribosylamino)uracil reductase]EC1.1.1.2 [Alcohol dehydrogenase (NADP(+))]EC1.1.1.202 [1,3-propanediol dehydrogenase]EC1.1.1.205 [IMP dehydrogenase]EC1.1.1.21 [Aldehyde reductase]EC1.1.1.210 [3-beta-(or 20-alpha)-hydroxysteroid dehydrogenase]EC1.1.1.215 [Gluconate 2-dehydrogenase]EC1.1.1.219 [Dihydrokaempferol 4-reductase]EC1.1.1.22 [UDP-glucose 6-dehydrogenase]EC1.1.1.220 [6-pyruvoyltetrahydropterin 2'-reductase]EC1.1.1.23 [Histidinol dehydrogenase]EC1.1.1.25 [Shikimate dehydrogenase]

The table shows fold-change in mean proportional representation of each EC between groups for each comparison. Values for nonsignificant EC changes in a comparison (adjusted p≥0.01, ShotgunFunctionalizeR) are reported as "NS".For EC.x in comparison A vs B, table displays (mean proportion of reads mapping to EC.x in A)/(mean proportion of reads mapping to EC.x in Note that ECs can have multiple KEGG pathway and category assignments.

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EC1.1.1.251 [Galactitol-1-phosphate 5-dehydrogenase]EC1.1.1.26 [Glyoxylate reductase]EC1.1.1.261 [Glycerol-1-phosphate dehydrogenase (NAD(P)(+))]EC1.1.1.262 [4-hydroxythreonine-4-phosphate dehydrogenase]EC1.1.1.264 [L-idonate 5-dehydrogenase]EC1.1.1.267 [1-deoxy-D-xylulose-5-phosphate reductoisomerase]EC1.1.1.27 [L-lactate dehydrogenase]EC1.1.1.271 [GDP-L-fucose synthase]EC1.1.1.272 [(R)-2-hydroxyacid dehydrogenase]EC1.1.1.274 [2,5-didehydrogluconate reductase]EC1.1.1.28 [D-lactate dehydrogenase]EC1.1.1.282 [Quinate/shikimate dehydrogenase]EC1.1.1.284 [S-(hydroxymethyl)glutathione dehydrogenase]EC1.1.1.29 [Glycerate dehydrogenase]EC1.1.1.290 [4-phosphoerythronate dehydrogenase]EC1.1.1.3 [Homoserine dehydrogenase]EC1.1.1.30 [3-hydroxybutyrate dehydrogenase]EC1.1.1.31 [3-hydroxyisobutyrate dehydrogenase]EC1.1.1.34 [Hydroxymethylglutaryl-CoA reductase (NADPH)]EC1.1.1.35 [3-hydroxyacyl-CoA dehydrogenase]EC1.1.1.36 [Acetoacetyl-CoA reductase]EC1.1.1.37 [Malate dehydrogenase]EC1.1.1.38 [Malate dehydrogenase (oxaloacetate-decarboxylating)]EC1.1.1.39 [Malate dehydrogenase (decarboxylating)]EC1.1.1.4 [(R,R)-butanediol dehydrogenase]EC1.1.1.40 [Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))]EC1.1.1.41 [Isocitrate dehydrogenase (NAD(+))]EC1.1.1.42 [Isocitrate dehydrogenase (NADP(+))]EC1.1.1.44 [Phosphogluconate dehydrogenase (decarboxylating)]EC1.1.1.47 [Glucose 1-dehydrogenase]EC1.1.1.49 [Glucose-6-phosphate dehydrogenase]EC1.1.1.5 [Acetoin dehydrogenase]EC1.1.1.53 [3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase]EC1.1.1.57 [Fructuronate reductase]EC1.1.1.58 [Tagaturonate reductase]EC1.1.1.6 [Glycerol dehydrogenase]EC1.1.1.60 [2-hydroxy-3-oxopropionate reductase]EC1.1.1.61 [4-hydroxybutyrate dehydrogenase]EC1.1.1.62 [Estradiol 17-beta-dehydrogenase]EC1.1.1.65 [Pyridoxine 4-dehydrogenase]EC1.1.1.67 [Mannitol 2-dehydrogenase]EC1.1.1.69 [Gluconate 5-dehydrogenase]EC1.1.1.77 [Lactaldehyde reductase]EC1.1.1.79 [Glyoxylate reductase (NADP(+))]EC1.1.1.8 [Glycerol-3-phosphate dehydrogenase (NAD(+))]EC1.1.1.81 [Hydroxypyruvate reductase]

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EC1.1.1.83 [D-malate dehydrogenase (decarboxylating)]EC1.1.1.85 [3-isopropylmalate dehydrogenase]EC1.1.1.86 [Ketol-acid reductoisomerase]EC1.1.1.9 [D-xylulose reductase]EC1.1.1.90 [Aryl-alcohol dehydrogenase]EC1.1.1.91 [Aryl-alcohol dehydrogenase (NADP(+))]EC1.1.1.93 [Tartrate dehydrogenase]EC1.1.1.94 [Glycerol-3-phosphate dehydrogenase (NAD(P)(+))]EC1.1.1.95 [Phosphoglycerate dehydrogenase]EC1.1.2.3 [L-lactate dehydrogenase (cytochrome)]EC1.1.2.4 [D-lactate dehydrogenase (cytochrome)]EC1.1.3.15 [(S)-2-hydroxy-acid oxidase]EC1.1.3.9 [Galactose oxidase]EC1.1.5.2 [Quinoprotein glucose dehydrogenase]EC1.1.5.3 [NA]EC1.1.5.4 [NA]EC1.1.99.- [NA]EC1.1.99.1 [Choline dehydrogenase]EC1.1.99.2 [2-hydroxyglutarate dehydrogenase]EC1.1.99.21 [D-sorbitol dehydrogenase (acceptor)]EC1.1.99.23 [Polyvinyl-alcohol dehydrogenase (acceptor)]EC1.1.99.25 [Quinate dehydrogenase (pyrroloquinoline-quinone)]EC1.1.99.28 [Glucose-fructose oxidoreductase]EC1.1.99.3 [Gluconate 2-dehydrogenase (acceptor)]EC1.1.99.8 [Alcohol dehydrogenase (acceptor)]EC1.10.2.- [NA]EC1.10.2.2 [Ubiquinol--cytochrome-c reductase]EC1.10.3.- [NA]EC1.10.3.2 [Laccase]EC1.10.99.1 [Plastoquinol--plastocyanin reductase]EC1.11.1.- [NA]EC1.11.1.10 [Chloride peroxidase]EC1.11.1.15 [Peroxiredoxin]EC1.11.1.5 [Cytochrome-c peroxidase]EC1.11.1.6 [Catalase]EC1.11.1.7 [Peroxidase]EC1.11.1.9 [Glutathione peroxidase]EC1.12.-.- [NA]EC1.12.1.2 [Hydrogen dehydrogenase]EC1.12.2.1 [Cytochrome-c3 hydrogenase]EC1.12.5.1 [Hydrogen:quinone oxidoreductase]EC1.12.7.2 [Ferredoxin hydrogenase]EC1.12.98.1 [Coenzyme F420 hydrogenase]EC1.12.99.6 [Hydrogenase (acceptor)]EC1.13.-.- [NA]EC1.13.11.- [NA]

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EC1.13.11.1 [Catechol 1,2-dioxygenase]EC1.13.11.15 [3,4-dihydroxyphenylacetate 2,3-dioxygenase]EC1.13.11.16 [3-carboxyethylcatechol 2,3-dioxygenase]EC1.13.11.2 [Catechol 2,3-dioxygenase]EC1.13.11.24 [Quercetin 2,3-dioxygenase]EC1.13.11.27 [4-hydroxyphenylpyruvate dioxygenase]EC1.13.11.3 [Protocatechuate 3,4-dioxygenase]EC1.13.11.39 [Biphenyl-2,3-diol 1,2-dioxygenase]EC1.13.11.4 [Gentisate 1,2-dioxygenase]EC1.13.11.43 [Lignostilbene alpha-beta-dioxygenase]EC1.13.11.5 [Homogentisate 1,2-dioxygenase]EC1.13.11.52 [Indoleamine 2,3-dioxygenase]EC1.13.11.6 [3-hydroxyanthranilate 3,4-dioxygenase]EC1.13.11.8 [Protocatechuate 4,5-dioxygenase]EC1.13.12.16 [NA]EC1.13.12.7 [Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing)]EC1.14.-.- [NA]EC1.14.1.- [NA]EC1.14.11.- [NA]EC1.14.11.17 [Taurine dioxygenase]EC1.14.11.2 [Procollagen-proline dioxygenase]EC1.14.11.4 [Procollagen-lysine 5-dioxygenase]EC1.14.12.17 [Nitric oxide dioxygenase]EC1.14.12.19 [3-phenylpropanoate dioxygenase]EC1.14.13.- [NA]EC1.14.13.1 [Salicylate 1-monooxygenase]EC1.14.13.2 [4-hydroxybenzoate 3-monooxygenase]EC1.14.13.22 [Cyclohexanone monooxygenase]EC1.14.13.3 [4-hydroxyphenylacetate 3-monooxygenase]EC1.14.13.30 [Leukotriene-B(4) 20-monooxygenase]EC1.14.13.39 [Nitric-oxide synthase]EC1.14.13.59 [L-lysine 6-monooxygenase (NADPH)]EC1.14.13.7 [Phenol 2-monooxygenase]EC1.14.13.72 [Methylsterol monooxygenase]EC1.14.13.81 [Magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase]EC1.14.13.82 [Vanillate monooxygenase]EC1.14.13.83 [Precorrin-3B synthase]EC1.14.14.- [NA]EC1.14.14.1 [Unspecific monooxygenase]EC1.14.14.3 [Alkanal monooxygenase (FMN-linked)]EC1.14.14.5 [Alkanesulfonate monooxygenase]EC1.14.15.3 [Alkane 1-monooxygenase]EC1.14.16.1 [Phenylalanine 4-monooxygenase]EC1.14.16.2 [Tyrosine 3-monooxygenase]EC1.14.16.4 [Tryptophan 5-monooxygenase]EC1.14.17.3 [Peptidylglycine monooxygenase]

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EC1.14.18.1 [Monophenol monooxygenase]EC1.14.18.2 [CMP-N-acetylneuraminate monooxygenase]EC1.14.19.- [NA]EC1.14.19.1 [Stearoyl-CoA 9-desaturase]EC1.14.19.2 [Acyl-[acyl-carrier-protein] desaturase]EC1.14.99.- [NA]EC1.14.99.3 [Heme oxygenase]EC1.14.99.7 [Squalene monooxygenase]EC1.15.1.1 [Superoxide dismutase]EC1.15.1.2 [Superoxide reductase]EC1.16.1.1 [Mercury(II) reductase]EC1.16.1.8 [[Methionine synthase] reductase]EC1.16.3.1 [Ferroxidase]EC1.16.8.1 [Cob(II)yrinic acid a,c-diamide reductase]EC1.17.1.1 [CDP-4-dehydro-6-deoxyglucose reductase]EC1.17.1.2 [4-hydroxy-3-methylbut-2-enyl diphosphate reductase]EC1.17.1.3 [Leucoanthocyanidin reductase]EC1.17.1.4 [Xanthine dehydrogenase]EC1.17.3.2 [Xanthine oxidase]EC1.17.4.1 [Ribonucleoside-diphosphate reductase]EC1.17.4.2 [Ribonucleoside-triphosphate reductase]EC1.17.7.1 [NA]EC1.18.-.- [NA]EC1.18.1.- [NA]EC1.18.1.1 [Rubredoxin--NAD(+) reductase]EC1.18.1.2 [Ferredoxin--NADP(+) reductase]EC1.18.1.3 [Ferredoxin--NAD(+) reductase]EC1.18.6.1 [Nitrogenase]EC1.19.6.1 [Nitrogenase (flavodoxin)]EC1.2.-.- [NA]EC1.2.1.- [NA]EC1.2.1.10 [Acetaldehyde dehydrogenase (acetylating)]EC1.2.1.11 [Aspartate-semialdehyde dehydrogenase]EC1.2.1.12 [Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)]EC1.2.1.16 [Succinate-semialdehyde dehydrogenase (NAD(P)(+))]EC1.2.1.19 [Aminobutyraldehyde dehydrogenase]EC1.2.1.2 [Formate dehydrogenase]EC1.2.1.21 [Glycolaldehyde dehydrogenase]EC1.2.1.22 [Lactaldehyde dehydrogenase]EC1.2.1.27 [Methylmalonate-semialdehyde dehydrogenase (acylating)]EC1.2.1.3 [Aldehyde dehydrogenase (NAD(+))]EC1.2.1.31 [L-aminoadipate-semialdehyde dehydrogenase]EC1.2.1.38 [N-acetyl-gamma-glutamyl-phosphate reductase]EC1.2.1.39 [Phenylacetaldehyde dehydrogenase]EC1.2.1.41 [Glutamate-5-semialdehyde dehydrogenase]EC1.2.1.45 [4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase]

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EC1.2.1.50 [Long-chain-fatty-acyl-CoA reductase]EC1.2.1.59 [Glyceraldehyde-3-phosphate dehydrogenase (NAD(P)(+)) (phosphorylating)]EC1.2.1.60 [5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase]EC1.2.1.68 [Coniferyl-aldehyde dehydrogenase]EC1.2.1.70 [Glutamyl-tRNA reductase]EC1.2.1.71 [Succinylglutamate-semialdehyde dehydrogenase]EC1.2.1.72 [Erythrose-4-phosphate dehydrogenase]EC1.2.1.8 [Betaine-aldehyde dehydrogenase]EC1.2.1.9 [Glyceraldehyde-3-phosphate dehydrogenase (NADP(+))]EC1.2.2.2 [Pyruvate dehydrogenase (cytochrome)]EC1.2.3.1 [Aldehyde oxidase]EC1.2.3.3 [Pyruvate oxidase]EC1.2.4.1 [Pyruvate dehydrogenase (acetyl-transferring)]EC1.2.4.2 [Oxoglutarate dehydrogenase (succinyl-transferring)]EC1.2.4.4 [3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)]EC1.2.7.- [NA]EC1.2.7.1 [Pyruvate synthase]EC1.2.7.3 [2-oxoglutarate synthase]EC1.2.7.4 [Carbon-monoxide dehydrogenase (ferredoxin)]EC1.2.7.5 [Aldehyde ferredoxin oxidoreductase]EC1.2.7.6 [Glyceraldehyde-3-phosphate dehydrogenase (ferredoxin)]EC1.2.7.7 [3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)]EC1.2.7.8 [Indolepyruvate ferredoxin oxidoreductase]EC1.2.99.2 [Carbon-monoxide dehydrogenase (acceptor)]EC1.2.99.5 [Formylmethanofuran dehydrogenase]EC1.2.99.7 [Aldehyde dehydrogenase (FAD-independent)]EC1.20.4.1 [Arsenate reductase (glutaredoxin)]EC1.20.98.1 [Arsenate reductase (azurin)]EC1.21.-.- [NA]EC1.21.4.1 [D-proline reductase (dithiol)]EC1.21.4.2 [Glycine reductase]EC1.21.4.3 [Sarcosine reductase]EC1.21.4.4 [Betaine reductase]EC1.3.1.- [NA]EC1.3.1.12 [Prephenate dehydrogenase]EC1.3.1.2 [Dihydropyrimidine dehydrogenase (NADP(+))]EC1.3.1.20 [Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase]EC1.3.1.21 [7-dehydrocholesterol reductase]EC1.3.1.24 [Biliverdin reductase]EC1.3.1.25 [1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase]EC1.3.1.26 [Dihydrodipicolinate reductase]EC1.3.1.28 [2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase]EC1.3.1.3 [Delta(4)-3-oxosteroid 5-beta-reductase]EC1.3.1.34 [2,4-dienoyl-CoA reductase (NADPH)]EC1.3.1.38 [Trans-2-enoyl-CoA reductase (NADPH)]EC1.3.1.44 [Trans-2-enoyl-CoA reductase (NAD(+))]

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EC1.3.1.54 [Precorrin-6A reductase]EC1.3.1.74 [2-alkenal reductase]EC1.3.1.76 [Precorrin-2 dehydrogenase]EC1.3.1.83 [NA]EC1.3.1.9 [Enoyl-[acyl-carrier-protein] reductase (NADH)]EC1.3.3.1 [Dihydroorotate oxidase]EC1.3.3.11 [Pyrroloquinoline-quinone synthase]EC1.3.3.3 [Coproporphyrinogen oxidase]EC1.3.3.4 [Protoporphyrinogen oxidase]EC1.3.3.6 [Acyl-CoA oxidase]EC1.3.5.1 [Succinate dehydrogenase (ubiquinone)]EC1.3.5.2 [NA]EC1.3.99.- [NA]EC1.3.99.1 [Succinate dehydrogenase]EC1.3.99.10 [Isovaleryl-CoA dehydrogenase]EC1.3.99.15 [Benzoyl-CoA reductase]EC1.3.99.16 [Isoquinoline 1-oxidoreductase]EC1.3.99.2 [Butyryl-CoA dehydrogenase]EC1.3.99.22 [Coproporphyrinogen dehydrogenase]EC1.3.99.23 [All-trans-retinol 13,14-reductase]EC1.3.99.3 [Acyl-CoA dehydrogenase]EC1.3.99.5 [3-oxo-5-alpha-steroid 4-dehydrogenase]EC1.3.99.7 [Glutaryl-CoA dehydrogenase]EC1.4.1.- [NA]EC1.4.1.1 [Alanine dehydrogenase]EC1.4.1.13 [Glutamate synthase (NADPH)]EC1.4.1.14 [Glutamate synthase (NADH)]EC1.4.1.16 [Diaminopimelate dehydrogenase]EC1.4.1.2 [Glutamate dehydrogenase]EC1.4.1.21 [Aspartate dehydrogenase]EC1.4.1.3 [Glutamate dehydrogenase (NAD(P)(+))]EC1.4.1.4 [Glutamate dehydrogenase (NADP(+))]EC1.4.1.9 [Leucine dehydrogenase]EC1.4.3.- [NA]EC1.4.3.16 [L-aspartate oxidase]EC1.4.3.19 [Glycine oxidase]EC1.4.3.21 [Primary-amine oxidase]EC1.4.3.3 [D-amino-acid oxidase]EC1.4.3.4 [Monoamine oxidase]EC1.4.3.5 [Pyridoxal 5'-phosphate synthase]EC1.4.4.2 [Glycine dehydrogenase (decarboxylating)]EC1.4.7.1 [Glutamate synthase (ferredoxin)]EC1.4.99.1 [D-amino-acid dehydrogenase]EC1.4.99.3 [Amine dehydrogenase]EC1.5.1.- [NA]EC1.5.1.10 [Saccharopine dehydrogenase (NADP(+), L-glutamate-forming)]

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EC1.5.1.12 [1-pyrroline-5-carboxylate dehydrogenase]EC1.5.1.2 [Pyrroline-5-carboxylate reductase]EC1.5.1.20 [Methylenetetrahydrofolate reductase (NAD(P)H)]EC1.5.1.28 [Opine dehydrogenase]EC1.5.1.29 [FMN reductase]EC1.5.1.3 [Dihydrofolate reductase]EC1.5.1.34 [6,7-dihydropteridine reductase]EC1.5.1.5 [Methylenetetrahydrofolate dehydrogenase (NADP(+))]EC1.5.1.7 [Saccharopine dehydrogenase (NAD(+), L-lysine-forming)]EC1.5.1.9 [Saccharopine dehydrogenase (NAD(+), L-glutamate-forming)]EC1.5.3.- [NA]EC1.5.3.1 [Sarcosine oxidase]EC1.5.3.14 [NA]EC1.5.3.16 [NA]EC1.5.3.17 [NA]EC1.5.5.- [NA]EC1.5.5.1 [Electron-transferring-flavoprotein dehydrogenase]EC1.5.99.1 [Sarcosine dehydrogenase]EC1.5.99.11 [5,10-methylenetetrahydromethanopterin reductase]EC1.5.99.12 [Cytokinin dehydrogenase]EC1.5.99.2 [Dimethylglycine dehydrogenase]EC1.5.99.6 [Spermidine dehydrogenase]EC1.5.99.8 [Proline dehydrogenase]EC1.5.99.9 [Methylenetetrahydromethanopterin dehydrogenase]EC1.6.-.- [NA]EC1.6.1.1 [NAD(P)(+) transhydrogenase (B-specific)]EC1.6.1.2 [NAD(P)(+) transhydrogenase (AB-specific)]EC1.6.2.4 [NADPH--hemoprotein reductase]EC1.6.3.- [NA]EC1.6.3.1 [NAD(P)H oxidase]EC1.6.4.- [NA]EC1.6.5.- [NA]EC1.6.5.2 [NAD(P)H dehydrogenase (quinone)]EC1.6.5.3 [NADH dehydrogenase (ubiquinone)]EC1.6.5.5 [NADPH:quinone reductase]EC1.6.6.- [NA]EC1.6.99.- [NA]EC1.6.99.1 [NADPH dehydrogenase]EC1.6.99.3 [NADH dehydrogenase]EC1.6.99.5 [NADH dehydrogenase (quinone)]EC1.7.-.- [NA]EC1.7.1.13 [PreQ(1) synthase]EC1.7.1.4 [Nitrite reductase (NAD(P)H)]EC1.7.1.7 [GMP reductase]EC1.7.2.1 [Nitrite reductase (NO-forming)]EC1.7.2.2 [Nitrite reductase (cytochrome; ammonia-forming)]

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EC1.7.2.3 [Trimethylamine-N-oxide reductase (cytochrome c)]EC1.7.3.3 [Urate oxidase]EC1.7.7.1 [Ferredoxin--nitrite reductase]EC1.7.99.1 [Hydroxylamine reductase]EC1.7.99.4 [Nitrate reductase]EC1.7.99.6 [Nitrous-oxide reductase]EC1.7.99.7 [Nitric-oxide reductase]EC1.8.-.- [NA]EC1.8.1.- [NA]EC1.8.1.2 [Sulfite reductase (NADPH)]EC1.8.1.4 [Dihydrolipoyl dehydrogenase]EC1.8.1.7 [Glutathione-disulfide reductase]EC1.8.1.8 [Protein-disulfide reductase]EC1.8.1.9 [Thioredoxin-disulfide reductase]EC1.8.2.- [NA]EC1.8.3.2 [Thiol oxidase]EC1.8.3.5 [Prenylcysteine oxidase]EC1.8.4.- [NA]EC1.8.4.11 [Peptide-methionine (S)-S-oxide reductase]EC1.8.4.12 [Peptide-methionine (R)-S-oxide reductase]EC1.8.4.8 [Phosphoadenylyl-sulfate reductase (thioredoxin)]EC1.8.98.1 [CoB--CoM heterodisulfide reductase]EC1.8.99.- [NA]EC1.8.99.2 [Adenylyl-sulfate reductase]EC1.8.99.3 [Hydrogensulfite reductase]EC1.9.3.- [NA]EC1.9.3.1 [Cytochrome-c oxidase]EC1.97.1.4 [[Formate-C-acetyltransferase]-activating enzyme]EC1.97.1.9 [Selenate reductase]EC2.-.-.- [NA]EC2.1.-.- [NA]EC2.1.1.- [NA]EC2.1.1.10 [Homocysteine S-methyltransferase]EC2.1.1.100 [Protein-S-isoprenylcysteine O-methyltransferase]EC2.1.1.101 [Macrocin O-methyltransferase]EC2.1.1.103 [Phosphoethanolamine N-methyltransferase]EC2.1.1.104 [Caffeoyl-CoA O-methyltransferase]EC2.1.1.107 [Uroporphyrinogen-III C-methyltransferase]EC2.1.1.113 [Site-specific DNA-methyltransferase (cytosine-N(4)-specific)]EC2.1.1.114 [Hexaprenyldihydroxybenzoate methyltransferase]EC2.1.1.125 [Histone-arginine N-methyltransferase]EC2.1.1.13 [Methionine synthase]EC2.1.1.130 [Precorrin-2 C(20)-methyltransferase]EC2.1.1.131 [Precorrin-3B C(17)-methyltransferase]EC2.1.1.132 [Precorrin-6Y C(5,15)-methyltransferase (decarboxylating)]EC2.1.1.133 [Precorrin-4 C(11)-methyltransferase]

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EC2.1.1.137 [Arsenite methyltransferase]EC2.1.1.14 [5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]EC2.1.1.144 [Trans-aconitate 2-methyltransferase]EC2.1.1.148 [Thymidylate synthase (FAD)]EC2.1.1.151 [Cobalt-factor II C(20)-methyltransferase]EC2.1.1.152 [Precorrin-6A synthase (deacetylating)]EC2.1.1.2 [Guanidinoacetate N-methyltransferase]EC2.1.1.31 [tRNA (guanine-N(1)-)-methyltransferase]EC2.1.1.32 [tRNA (guanine-N(2)-)-methyltransferase]EC2.1.1.33 [tRNA (guanine-N(7)-)-methyltransferase]EC2.1.1.34 [tRNA guanosine-2'-O-methyltransferase]EC2.1.1.35 [tRNA (uracil-5-)-methyltransferase]EC2.1.1.36 [tRNA (adenine-N(1)-)-methyltransferase]EC2.1.1.37 [DNA (cytosine-5-)-methyltransferase]EC2.1.1.41 [Sterol 24-C-methyltransferase]EC2.1.1.43 [Histone-lysine N-methyltransferase]EC2.1.1.45 [Thymidylate synthase]EC2.1.1.48 [rRNA (adenine-N(6)-)-methyltransferase]EC2.1.1.51 [rRNA (guanine-N(1)-)-methyltransferase]EC2.1.1.52 [rRNA (guanine-N(2)-)-methyltransferase]EC2.1.1.56 [mRNA (guanine-N(7)-)-methyltransferase]EC2.1.1.61 [tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase]EC2.1.1.63 [Methylated-DNA--[protein]-cysteine S-methyltransferase]EC2.1.1.64 [3-demethylubiquinone-9 3-O-methyltransferase]EC2.1.1.67 [Thiopurine S-methyltransferase]EC2.1.1.72 [Site-specific DNA-methyltransferase (adenine-specific)]EC2.1.1.77 [Protein-L-isoaspartate(D-aspartate) O-methyltransferase]EC2.1.1.79 [Cyclopropane-fatty-acyl-phospholipid synthase]EC2.1.1.80 [Protein-glutamate O-methyltransferase]EC2.1.1.86 [Tetrahydromethanopterin S-methyltransferase]EC2.1.1.90 [Methanol--5-hydroxybenzimidazolylcobamide Co-methyltransferase]EC2.1.1.98 [Diphthine synthase]EC2.1.2.- [NA]EC2.1.2.1 [Glycine hydroxymethyltransferase]EC2.1.2.10 [Aminomethyltransferase]EC2.1.2.11 [3-methyl-2-oxobutanoate hydroxymethyltransferase]EC2.1.2.2 [Phosphoribosylglycinamide formyltransferase]EC2.1.2.3 [Phosphoribosylaminoimidazolecarboxamide formyltransferase]EC2.1.2.5 [Glutamate formimidoyltransferase]EC2.1.2.9 [Methionyl-tRNA formyltransferase]EC2.1.3.- [NA]EC2.1.3.11 [N-succinylornithine carbamoyltransferase]EC2.1.3.2 [Aspartate carbamoyltransferase]EC2.1.3.3 [Ornithine carbamoyltransferase]EC2.1.3.6 [Putrescine carbamoyltransferase]EC2.2.1.1 [Transketolase]

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EC2.2.1.2 [Transaldolase]EC2.2.1.6 [Acetolactate synthase]EC2.2.1.7 [1-deoxy-D-xylulose-5-phosphate synthase]EC2.2.1.9 [2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid]EC2.3.1.- [NA]EC2.3.1.1 [Amino-acid N-acetyltransferase]EC2.3.1.101 [Formylmethanofuran--tetrahydromethanopterin N-formyltransferase]EC2.3.1.109 [Arginine N-succinyltransferase]EC2.3.1.117 [2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase]EC2.3.1.118 [N-hydroxyarylamine O-acetyltransferase]EC2.3.1.12 [Dihydrolipoyllysine-residue acetyltransferase]EC2.3.1.128 [Ribosomal-protein-alanine N-acetyltransferase]EC2.3.1.129 [Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase]EC2.3.1.137 [Carnitine O-octanoyltransferase]EC2.3.1.15 [Glycerol-3-phosphate O-acyltransferase]EC2.3.1.157 [Glucosamine-1-phosphate N-acetyltransferase]EC2.3.1.158 [Phospholipid:diacylglycerol acyltransferase]EC2.3.1.16 [Acetyl-CoA C-acyltransferase]EC2.3.1.164 [Isopenicillin-N N-acyltransferase]EC2.3.1.168 [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase]EC2.3.1.169 [CO-methylating acetyl-CoA synthase]EC2.3.1.176 [Propanoyl-CoA C-acyltransferase]EC2.3.1.178 [Diaminobutyrate acetyltransferase]EC2.3.1.179 [Beta-ketoacyl-acyl-carrier-protein synthase II]EC2.3.1.18 [Galactoside O-acetyltransferase]EC2.3.1.180 [Beta-ketoacyl-acyl-carrier-protein synthase III]EC2.3.1.181 [Lipoyl(octanoyl) transferase]EC2.3.1.182 [(R)-citramalate synthase]EC2.3.1.183 [Phosphinothricin acetyltransferase]EC2.3.1.19 [Phosphate butyryltransferase]EC2.3.1.20 [Diacylglycerol O-acyltransferase]EC2.3.1.21 [Carnitine O-palmitoyltransferase]EC2.3.1.23 [1-acylglycerophosphocholine O-acyltransferase]EC2.3.1.26 [Sterol O-acyltransferase]EC2.3.1.28 [Chloramphenicol O-acetyltransferase]EC2.3.1.29 [Glycine C-acetyltransferase]EC2.3.1.30 [Serine O-acetyltransferase]EC2.3.1.31 [Homoserine O-acetyltransferase]EC2.3.1.35 [Glutamate N-acetyltransferase]EC2.3.1.37 [5-aminolevulinate synthase]EC2.3.1.39 [[Acyl-carrier-protein] S-malonyltransferase]EC2.3.1.4 [Glucosamine-phosphate N-acetyltransferase]EC2.3.1.41 [Beta-ketoacyl-acyl-carrier-protein synthase I]EC2.3.1.42 [Glycerone-phosphate O-acyltransferase]EC2.3.1.43 [Phosphatidylcholine--sterol O-acyltransferase]EC2.3.1.46 [Homoserine O-succinyltransferase]

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EC2.3.1.47 [8-amino-7-oxononanoate synthase]EC2.3.1.48 [Histone acetyltransferase]EC2.3.1.50 [Serine C-palmitoyltransferase]EC2.3.1.51 [1-acylglycerol-3-phosphate O-acyltransferase]EC2.3.1.54 [Formate C-acetyltransferase]EC2.3.1.57 [Diamine N-acetyltransferase]EC2.3.1.61 [Dihydrolipoyllysine-residue succinyltransferase]EC2.3.1.67 [1-alkylglycerophosphocholine O-acetyltransferase]EC2.3.1.7 [Carnitine O-acetyltransferase]EC2.3.1.78 [Heparan-alpha-glucosaminide N-acetyltransferase]EC2.3.1.79 [Maltose O-acetyltransferase]EC2.3.1.8 [Phosphate acetyltransferase]EC2.3.1.81 [Aminoglycoside N(3')-acetyltransferase]EC2.3.1.82 [Aminoglycoside N(6')-acetyltransferase]EC2.3.1.85 [Fatty-acid synthase]EC2.3.1.86 [Fatty-acyl-CoA synthase]EC2.3.1.87 [Aralkylamine N-acetyltransferase]EC2.3.1.88 [Peptide alpha-N-acetyltransferase]EC2.3.1.9 [Acetyl-CoA C-acetyltransferase]EC2.3.1.94 [6-deoxyerythronolide-B synthase]EC2.3.1.97 [Glycylpeptide N-tetradecanoyltransferase]EC2.3.2.- [NA]EC2.3.2.10 [UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase]EC2.3.2.13 [Protein-glutamine gamma-glutamyltransferase]EC2.3.2.2 [Gamma-glutamyltransferase]EC2.3.2.4 [Gamma-glutamylcyclotransferase]EC2.3.2.5 [Glutaminyl-peptide cyclotransferase]EC2.3.2.6 [Leucyltransferase]EC2.3.2.8 [Arginyltransferase]EC2.3.3.1 [Citrate (Si)-synthase]EC2.3.3.10 [Hydroxymethylglutaryl-CoA synthase]EC2.3.3.13 [2-isopropylmalate synthase]EC2.3.3.14 [Homocitrate synthase]EC2.3.3.5 [2-methylcitrate synthase]EC2.3.3.8 [ATP citrate synthase]EC2.3.3.9 [Malate synthase]EC2.4.-.- [NA]EC2.4.1.- [NA]EC2.4.1.1 [Phosphorylase]EC2.4.1.10 [Levansucrase]EC2.4.1.101 [Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase]EC2.4.1.109 [Dolichyl-phosphate-mannose-protein mannosyltransferase]EC2.4.1.11 [Glycogen(starch) synthase]EC2.4.1.117 [Dolichyl-phosphate beta-glucosyltransferase]EC2.4.1.119 [Dolichyl-diphosphooligosaccharide--protein glycotransferase]EC2.4.1.12 [Cellulose synthase (UDP-forming)]

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EC2.4.1.129 [Peptidoglycan glycosyltransferase]EC2.4.1.13 [Sucrose synthase]EC2.4.1.130 [Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase]EC2.4.1.132 [Glycolipid 3-alpha-mannosyltransferase]EC2.4.1.133 [Xylosylprotein 4-beta-galactosyltransferase]EC2.4.1.134 [Galactosylxylosylprotein 3-beta-galactosyltransferase]EC2.4.1.135 [Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase]EC2.4.1.14 [Sucrose-phosphate synthase]EC2.4.1.141 [N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase]EC2.4.1.142 [Chitobiosyldiphosphodolichol beta-mannosyltransferase]EC2.4.1.145 [Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase]EC2.4.1.147 [Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-]EC2.4.1.15 [Alpha,alpha-trehalose-phosphate synthase (UDP-forming)]EC2.4.1.150 [N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase]EC2.4.1.152 [4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase]EC2.4.1.157 [1,2-diacylglycerol 3-glucosyltransferase]EC2.4.1.16 [Chitin synthase]EC2.4.1.166 [Raffinose--raffinose alpha-galactosyltransferase]EC2.4.1.17 [Glucuronosyltransferase]EC2.4.1.173 [Sterol 3-beta-glucosyltransferase]EC2.4.1.174 [Glucuronylgalactosylproteoglycan 4-beta-N-]EC2.4.1.175 [Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-]EC2.4.1.18 [1,4-alpha-glucan branching enzyme]EC2.4.1.182 [Lipid-A-disaccharide synthase]EC2.4.1.183 [Alpha-1,3-glucan synthase]EC2.4.1.186 [Glycogenin glucosyltransferase]EC2.4.1.187 [N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-]EC2.4.1.19 [Cyclomaltodextrin glucanotransferase]EC2.4.1.198 [Phosphatidylinositol N-acetylglucosaminyltransferase]EC2.4.1.20 [Cellobiose phosphorylase]EC2.4.1.21 [Starch synthase]EC2.4.1.212 [Hyaluronan synthase]EC2.4.1.213 [Glucosylglycerol-phosphate synthase]EC2.4.1.214 [Glycoprotein 3-alpha-L-fucosyltransferase]EC2.4.1.216 [Trehalose 6-phosphate phosphorylase]EC2.4.1.221 [Peptide-O-fucosyltransferase]EC2.4.1.226 [N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase]EC2.4.1.227 [Undecaprenyldiphospho-muramoylpentapeptide beta-N-]EC2.4.1.230 [Kojibiose phosphorylase]EC2.4.1.232 [Initiation-specific alpha-1,6-mannosyltransferase]EC2.4.1.246 [NA]EC2.4.1.25 [4-alpha-glucanotransferase]EC2.4.1.34 [1,3-beta-glucan synthase]EC2.4.1.37 [Fucosylgalactoside 3-alpha-galactosyltransferase]EC2.4.1.4 [Amylosucrase]EC2.4.1.40 [Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase]

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EC2.4.1.41 [Polypeptide N-acetylgalactosaminyltransferase]EC2.4.1.5 [Dextransucrase]EC2.4.1.52 [Poly(glycerol-phosphate) alpha-glucosyltransferase]EC2.4.1.56 [Lipopolysaccharide N-acetylglucosaminyltransferase]EC2.4.1.57 [Phosphatidylinositol alpha-mannosyltransferase]EC2.4.1.58 [Lipopolysaccharide glucosyltransferase I]EC2.4.1.67 [Galactinol--raffinose galactosyltransferase]EC2.4.1.68 [Glycoprotein 6-alpha-L-fucosyltransferase]EC2.4.1.7 [Sucrose phosphorylase]EC2.4.1.79 [Globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase]EC2.4.1.8 [Maltose phosphorylase]EC2.4.1.80 [Ceramide glucosyltransferase]EC2.4.1.83 [Dolichyl-phosphate beta-D-mannosyltransferase]EC2.4.1.87 [N-acetyllactosaminide 3-alpha-galactosyltransferase]EC2.4.1.88 [Globoside alpha-N-acetylgalactosaminyltransferase]EC2.4.1.90 [N-acetyllactosamine synthase]EC2.4.1.92 [(N-acetylneuraminyl)-galactosylglucosylceramide]EC2.4.2.- [NA]EC2.4.2.1 [Purine-nucleoside phosphorylase]EC2.4.2.10 [Orotate phosphoribosyltransferase]EC2.4.2.11 [Nicotinate phosphoribosyltransferase]EC2.4.2.12 [Nicotinamide phosphoribosyltransferase]EC2.4.2.14 [Amidophosphoribosyltransferase]EC2.4.2.17 [ATP phosphoribosyltransferase]EC2.4.2.18 [Anthranilate phosphoribosyltransferase]EC2.4.2.19 [Nicotinate-nucleotide diphosphorylase (carboxylating)]EC2.4.2.2 [Pyrimidine-nucleoside phosphorylase]EC2.4.2.21 [Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase]EC2.4.2.22 [Xanthine phosphoribosyltransferase]EC2.4.2.26 [Protein xylosyltransferase]EC2.4.2.28 [S-methyl-5'-thioadenosine phosphorylase]EC2.4.2.29 [tRNA-guanine transglycosylase]EC2.4.2.3 [Uridine phosphorylase]EC2.4.2.30 [NAD(+) ADP-ribosyltransferase]EC2.4.2.31 [NAD(P)(+)--protein-arginine ADP-ribosyltransferase]EC2.4.2.37 [NAD(+)--dinitrogen-reductase ADP-D-ribosyltransferase]EC2.4.2.39 [Xyloglucan 6-xylosyltransferase]EC2.4.2.4 [Thymidine phosphorylase]EC2.4.2.6 [Nucleoside deoxyribosyltransferase]EC2.4.2.7 [Adenine phosphoribosyltransferase]EC2.4.2.8 [Hypoxanthine phosphoribosyltransferase]EC2.4.2.9 [Uracil phosphoribosyltransferase]EC2.4.99.- [NA]EC2.4.99.1 [Beta-galactoside alpha-2,6-sialyltransferase]EC2.4.99.3 [Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase]EC2.5.1.- [NA]

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EC2.5.1.1 [Dimethylallyltranstransferase]EC2.5.1.10 [Geranyltranstransferase]EC2.5.1.15 [Dihydropteroate synthase]EC2.5.1.16 [Spermidine synthase]EC2.5.1.17 [Cob(I)yrinic acid a,c-diamide adenosyltransferase]EC2.5.1.18 [Glutathione transferase]EC2.5.1.19 [3-phosphoshikimate 1-carboxyvinyltransferase]EC2.5.1.21 [Squalene synthase]EC2.5.1.26 [Alkylglycerone-phosphate synthase]EC2.5.1.29 [Farnesyltranstransferase]EC2.5.1.3 [Thiamine-phosphate diphosphorylase]EC2.5.1.30 [Trans-hexaprenyltranstransferase]EC2.5.1.31 [Di-trans,poly-cis-decaprenylcistransferase]EC2.5.1.32 [Phytoene synthase]EC2.5.1.43 [Nicotianamine synthase]EC2.5.1.44 [Homospermidine synthase]EC2.5.1.46 [Deoxyhypusine synthase]EC2.5.1.47 [Cysteine synthase]EC2.5.1.48 [Cystathionine gamma-synthase]EC2.5.1.49 [O-acetylhomoserine aminocarboxypropyltransferase]EC2.5.1.54 [3-deoxy-7-phosphoheptulonate synthase]EC2.5.1.55 [3-deoxy-8-phosphooctulonate synthase]EC2.5.1.56 [N-acetylneuraminate synthase]EC2.5.1.58 [Protein farnesyltransferase]EC2.5.1.59 [Protein geranylgeranyltransferase type I]EC2.5.1.6 [Methionine adenosyltransferase]EC2.5.1.60 [Protein geranylgeranyltransferase type II]EC2.5.1.61 [Hydroxymethylbilane synthase]EC2.5.1.62 [Chlorophyll synthase]EC2.5.1.7 [UDP-N-acetylglucosamine 1-carboxyvinyltransferase]EC2.5.1.72 [Quinolinate synthase]EC2.5.1.73 [NA]EC2.5.1.75 [NA]EC2.5.1.9 [Riboflavin synthase]EC2.6.-.- [NA]EC2.6.1.- [NA]EC2.6.1.1 [Aspartate transaminase]EC2.6.1.11 [Acetylornithine transaminase]EC2.6.1.13 [Ornithine aminotransferase]EC2.6.1.16 [Glutamine--fructose-6-phosphate transaminase (isomerizing)]EC2.6.1.17 [Succinyldiaminopimelate transaminase]EC2.6.1.18 [Beta-alanine--pyruvate transaminase]EC2.6.1.19 [4-aminobutyrate transaminase]EC2.6.1.2 [Alanine transaminase]EC2.6.1.21 [D-amino-acid transaminase]EC2.6.1.22 [(S)-3-amino-2-methylpropionate transaminase]

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EC2.6.1.37 [2-aminoethylphosphonate--pyruvate transaminase]EC2.6.1.39 [2-aminoadipate transaminase]EC2.6.1.42 [Branched-chain-amino-acid transaminase]EC2.6.1.45 [Serine--glyoxylate transaminase]EC2.6.1.5 [Tyrosine transaminase]EC2.6.1.52 [Phosphoserine transaminase]EC2.6.1.57 [Aromatic-amino-acid transaminase]EC2.6.1.62 [Adenosylmethionine--8-amino-7-oxononanoate transaminase]EC2.6.1.66 [Valine--pyruvate transaminase]EC2.6.1.7 [Kynurenine--oxoglutarate transaminase]EC2.6.1.76 [Diaminobutyrate--2-oxoglutarate transaminase]EC2.6.1.81 [Succinylornithine transaminase]EC2.6.1.82 [Putrescine aminotransferase]EC2.6.1.83 [LL-diaminopimelate aminotransferase]EC2.6.1.85 [Aminodeoxychorismate synthase]EC2.6.1.86 [2-amino-4-deoxychorismate synthase]EC2.6.1.9 [Histidinol-phosphate transaminase]EC2.6.99.2 [Pyridoxine 5'-phosphate synthase]EC2.7.-.- [NA]EC2.7.1.- [NA]EC2.7.1.1 [Hexokinase]EC2.7.1.100 [S-methyl-5-thioribose kinase]EC2.7.1.105 [6-phosphofructo-2-kinase]EC2.7.1.107 [Diacylglycerol kinase]EC2.7.1.108 [Dolichol kinase]EC2.7.1.11 [6-phosphofructokinase]EC2.7.1.113 [Deoxyguanosine kinase]EC2.7.1.12 [Gluconokinase]EC2.7.1.127 [Inositol-trisphosphate 3-kinase]EC2.7.1.130 [Tetraacyldisaccharide 4'-kinase]EC2.7.1.137 [Phosphatidylinositol 3-kinase]EC2.7.1.14 [Sedoheptulokinase]EC2.7.1.144 [Tagatose-6-phosphate kinase]EC2.7.1.146 [ADP-specific phosphofructokinase]EC2.7.1.148 [4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase]EC2.7.1.149 [1-phosphatidylinositol-5-phosphate 4-kinase]EC2.7.1.15 [Ribokinase]EC2.7.1.153 [Phosphatidylinositol-4,5-bisphosphate 3-kinase]EC2.7.1.154 [Phosphatidylinositol-4-phosphate 3-kinase]EC2.7.1.156 [Adenosylcobinamide kinase]EC2.7.1.16 [Ribulokinase]EC2.7.1.161 [CTP-dependent riboflavin kinase]EC2.7.1.162 [N-acetylhexosamine 1-kinase]EC2.7.1.164 [NA]EC2.7.1.17 [Xylulokinase]EC2.7.1.19 [Phosphoribulokinase]

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EC2.7.1.2 [Glucokinase]EC2.7.1.20 [Adenosine kinase]EC2.7.1.21 [Thymidine kinase]EC2.7.1.23 [NAD(+) kinase]EC2.7.1.24 [Dephospho-CoA kinase]EC2.7.1.25 [Adenylyl-sulfate kinase]EC2.7.1.26 [Riboflavin kinase]EC2.7.1.29 [Glycerone kinase]EC2.7.1.30 [Glycerol kinase]EC2.7.1.31 [Glycerate kinase]EC2.7.1.32 [Choline kinase]EC2.7.1.33 [Pantothenate kinase]EC2.7.1.35 [Pyridoxal kinase]EC2.7.1.36 [Mevalonate kinase]EC2.7.1.37 [Transferred entry: 2.7.11.1]EC2.7.1.39 [Homoserine kinase]EC2.7.1.4 [Fructokinase]EC2.7.1.40 [Pyruvate kinase]EC2.7.1.41 [Glucose-1-phosphate phosphodismutase]EC2.7.1.45 [2-dehydro-3-deoxygluconokinase]EC2.7.1.48 [Uridine kinase]EC2.7.1.49 [Hydroxymethylpyrimidine kinase]EC2.7.1.5 [Rhamnulokinase]EC2.7.1.50 [Hydroxyethylthiazole kinase]EC2.7.1.51 [L-fuculokinase]EC2.7.1.52 [Fucokinase]EC2.7.1.53 [L-xylulokinase]EC2.7.1.55 [Allose kinase]EC2.7.1.56 [1-phosphofructokinase]EC2.7.1.58 [2-dehydro-3-deoxygalactonokinase]EC2.7.1.59 [N-acetylglucosamine kinase]EC2.7.1.6 [Galactokinase]EC2.7.1.60 [N-acylmannosamine kinase]EC2.7.1.63 [Polyphosphate--glucose phosphotransferase]EC2.7.1.67 [1-phosphatidylinositol 4-kinase]EC2.7.1.68 [1-phosphatidylinositol-4-phosphate 5-kinase]EC2.7.1.69 [Protein-N(pi)-phosphohistidine--sugar phosphotransferase]EC2.7.1.71 [Shikimate kinase]EC2.7.1.73 [Inosine kinase]EC2.7.1.74 [Deoxycytidine kinase]EC2.7.1.82 [Ethanolamine kinase]EC2.7.1.89 [Thiamine kinase]EC2.7.1.90 [Diphosphate--fructose-6-phosphate 1-phosphotransferase]EC2.7.1.91 [Sphinganine kinase]EC2.7.1.92 [5-dehydro-2-deoxygluconokinase]EC2.7.1.95 [Kanamycin kinase]

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EC2.7.10.- [NA]EC2.7.10.1 [Receptor protein-tyrosine kinase]EC2.7.10.2 [Non-specific protein-tyrosine kinase]EC2.7.11.- [NA]EC2.7.11.1 [Non-specific serine/threonine protein kinase]EC2.7.11.10 [I-kappa-B kinase]EC2.7.11.11 [cAMP-dependent protein kinase]EC2.7.11.12 [cGMP-dependent protein kinase]EC2.7.11.13 [Protein kinase C]EC2.7.11.16 [[G-protein-coupled receptor] kinase]EC2.7.11.17 [Calcium/calmodulin-dependent protein kinase]EC2.7.11.18 [[Myosin light-chain] kinase]EC2.7.11.2 [[Pyruvate dehydrogenase (acetyl-transferring)] kinase]EC2.7.11.21 [Polo kinase]EC2.7.11.22 [Cyclin-dependent kinase]EC2.7.11.24 [Mitogen-activated protein kinase]EC2.7.11.25 [Mitogen-activated protein kinase kinase kinase]EC2.7.11.30 [Receptor protein serine/threonine kinase]EC2.7.11.5 [[Isocitrate dehydrogenase (NADP(+))] kinase]EC2.7.12.1 [Dual-specificity kinase]EC2.7.12.2 [Mitogen-activated protein kinase kinase]EC2.7.13.- [NA]EC2.7.13.1 [Protein-histidine pros-kinase]EC2.7.13.3 [Histidine kinase]EC2.7.2.- [NA]EC2.7.2.1 [Acetate kinase]EC2.7.2.11 [Glutamate 5-kinase]EC2.7.2.15 [Propionate kinase]EC2.7.2.2 [Carbamate kinase]EC2.7.2.3 [Phosphoglycerate kinase]EC2.7.2.4 [Aspartate kinase]EC2.7.2.7 [Butyrate kinase]EC2.7.2.8 [Acetylglutamate kinase]EC2.7.3.- [NA]EC2.7.3.2 [Creatine kinase]EC2.7.3.3 [Arginine kinase]EC2.7.3.9 [Phosphoenolpyruvate--protein phosphotransferase]EC2.7.4.- [NA]EC2.7.4.1 [Polyphosphate kinase]EC2.7.4.14 [Cytidylate kinase]EC2.7.4.16 [Thiamine-phosphate kinase]EC2.7.4.2 [Phosphomevalonate kinase]EC2.7.4.21 [Inositol-hexakisphosphate kinase]EC2.7.4.22 [UMP kinase]EC2.7.4.23 [Ribose 1,5-bisphosphate phosphokinase]EC2.7.4.24 [Diphosphoinositol-pentakisphosphate kinase]

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EC2.7.4.3 [Adenylate kinase]EC2.7.4.6 [Nucleoside-diphosphate kinase]EC2.7.4.7 [Phosphomethylpyrimidine kinase]EC2.7.4.8 [Guanylate kinase]EC2.7.4.9 [dTMP kinase]EC2.7.6.1 [Ribose-phosphate diphosphokinase]EC2.7.6.2 [Thiamine diphosphokinase]EC2.7.6.3 [2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase]EC2.7.6.5 [GTP diphosphokinase]EC2.7.7.- [NA]EC2.7.7.1 [Nicotinamide-nucleotide adenylyltransferase]EC2.7.7.10 [UTP--hexose-1-phosphate uridylyltransferase]EC2.7.7.12 [UDP-glucose--hexose-1-phosphate uridylyltransferase]EC2.7.7.13 [Mannose-1-phosphate guanylyltransferase]EC2.7.7.14 [Ethanolamine-phosphate cytidylyltransferase]EC2.7.7.15 [Choline-phosphate cytidylyltransferase]EC2.7.7.18 [Nicotinate-nucleotide adenylyltransferase]EC2.7.7.19 [Polynucleotide adenylyltransferase]EC2.7.7.2 [FAD synthetase]EC2.7.7.22 [Mannose-1-phosphate guanylyltransferase (GDP)]EC2.7.7.23 [UDP-N-acetylglucosamine diphosphorylase]EC2.7.7.24 [Glucose-1-phosphate thymidylyltransferase]EC2.7.7.27 [Glucose-1-phosphate adenylyltransferase]EC2.7.7.3 [Pantetheine-phosphate adenylyltransferase]EC2.7.7.33 [Glucose-1-phosphate cytidylyltransferase]EC2.7.7.38 [3-deoxy-manno-octulosonate cytidylyltransferase]EC2.7.7.39 [Glycerol-3-phosphate cytidylyltransferase]EC2.7.7.4 [Sulfate adenylyltransferase]EC2.7.7.41 [Phosphatidate cytidylyltransferase]EC2.7.7.42 [[Glutamate--ammonia-ligase] adenylyltransferase]EC2.7.7.43 [N-acylneuraminate cytidylyltransferase]EC2.7.7.48 [RNA-directed RNA polymerase]EC2.7.7.49 [RNA-directed DNA polymerase]EC2.7.7.50 [mRNA guanylyltransferase]EC2.7.7.53 [ATP adenylyltransferase]EC2.7.7.56 [tRNA nucleotidyltransferase]EC2.7.7.58 [(2,3-dihydroxybenzoyl)adenylate synthase]EC2.7.7.59 [[Protein-PII] uridylyltransferase]EC2.7.7.6 [DNA-directed RNA polymerase]EC2.7.7.60 [2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase]EC2.7.7.61 [Citrate lyase holo-[acyl-carrier-protein] synthase]EC2.7.7.62 [Adenosylcobinamide-phosphate guanylyltransferase]EC2.7.7.63 [Lipoate--protein ligase]EC2.7.7.65 [Diguanylate kinase]EC2.7.7.7 [DNA-directed DNA polymerase]EC2.7.7.8 [Polyribonucleotide nucleotidyltransferase]

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EC2.7.7.9 [UTP--glucose-1-phosphate uridylyltransferase]EC2.7.8.- [NA]EC2.7.8.11 [CDP-diacylglycerol--inositol 3-phosphatidyltransferase]EC2.7.8.12 [CDP-glycerol glycerophosphotransferase]EC2.7.8.13 [Phospho-N-acetylmuramoyl-pentapeptide-transferase]EC2.7.8.15 [UDP-N-acetylglucosamine--dolichyl-phosphate]EC2.7.8.17 [UDP-N-acetylglucosamine--lysosomal-enzyme]EC2.7.8.20 [Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase]EC2.7.8.25 [Triphosphoribosyl-dephospho-CoA synthase]EC2.7.8.26 [Adenosylcobinamide-GDP ribazoletransferase]EC2.7.8.5 [CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase]EC2.7.8.6 [Undecaprenyl-phosphate galactose phosphotransferase]EC2.7.8.7 [Holo-[acyl-carrier-protein] synthase]EC2.7.8.8 [CDP-diacylglycerol--serine O-phosphatidyltransferase]EC2.7.9.1 [Pyruvate, phosphate dikinase]EC2.7.9.2 [Pyruvate, water dikinase]EC2.7.9.3 [Selenide, water dikinase]EC2.8.1.- [NA]EC2.8.1.1 [Thiosulfate sulfurtransferase]EC2.8.1.2 [3-mercaptopyruvate sulfurtransferase]EC2.8.1.6 [Biotin synthase]EC2.8.1.7 [Cysteine desulfurase]EC2.8.1.8 [Lipoyl synthase]EC2.8.2.- [NA]EC2.8.2.20 [Protein-tyrosine sulfotransferase]EC2.8.2.21 [Keratan sulfotransferase]EC2.8.2.22 [Aryl-sulfate sulfotransferase]EC2.8.2.5 [Chondroitin 4-sulfotransferase]EC2.8.3.- [NA]EC2.8.3.1 [Propionate CoA-transferase]EC2.8.3.12 [Glutaconate CoA-transferase]EC2.8.3.16 [Formyl-CoA transferase]EC2.8.3.5 [3-oxoacid CoA-transferase]EC2.8.3.6 [3-oxoadipate CoA-transferase]EC2.8.3.8 [Acetate CoA-transferase]EC2.8.3.9 [Butyrate--acetoacetate CoA-transferase]EC2.8.4.1 [Coenzyme-B sulfoethylthiotransferase]EC2.9.1.- [NA]EC2.9.1.1 [L-seryl-tRNA(Sec) selenium transferase]EC2F7_8 [NA]EC3.-.-.- [NA]EC3.1.-.- [NA]EC3.1.1.- [NA]EC3.1.1.1 [Carboxylesterase]EC3.1.1.11 [Pectinesterase]EC3.1.1.17 [Gluconolactonase]

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EC3.1.1.2 [Arylesterase]EC3.1.1.20 [Tannase]EC3.1.1.23 [Acylglycerol lipase]EC3.1.1.24 [3-oxoadipate enol-lactonase]EC3.1.1.29 [Aminoacyl-tRNA hydrolase]EC3.1.1.3 [Triacylglycerol lipase]EC3.1.1.31 [6-phosphogluconolactonase]EC3.1.1.32 [Phospholipase A(1)]EC3.1.1.34 [Lipoprotein lipase]EC3.1.1.4 [Phospholipase A(2)]EC3.1.1.41 [Cephalosporin-C deacetylase]EC3.1.1.45 [Carboxymethylenebutenolidase]EC3.1.1.47 [1-alkyl-2-acetylglycerophosphocholine esterase]EC3.1.1.5 [Lysophospholipase]EC3.1.1.53 [Sialate O-acetylesterase]EC3.1.1.6 [Acetylesterase]EC3.1.1.61 [Protein-glutamate methylesterase]EC3.1.1.7 [Acetylcholinesterase]EC3.1.1.72 [Acetylxylan esterase]EC3.1.1.73 [Feruloyl esterase]EC3.1.1.75 [Poly(3-hydroxybutyrate) depolymerase]EC3.1.1.79 [Hormone-sensitive lipase]EC3.1.1.8 [Cholinesterase]EC3.1.1.81 [Quorum-quenching N-acyl-homoserine lactonase]EC3.1.11.- [NA]EC3.1.11.1 [Exodeoxyribonuclease I]EC3.1.11.2 [Exodeoxyribonuclease III]EC3.1.11.3 [Exodeoxyribonuclease (lambda-induced)]EC3.1.11.5 [Exodeoxyribonuclease V]EC3.1.11.6 [Exodeoxyribonuclease VII]EC3.1.13.- [NA]EC3.1.13.1 [Exoribonuclease II]EC3.1.13.4 [Poly(A)-specific ribonuclease]EC3.1.13.5 [Ribonuclease D]EC3.1.2.- [NA]EC3.1.2.1 [Acetyl-CoA hydrolase]EC3.1.2.12 [S-formylglutathione hydrolase]EC3.1.2.14 [Oleoyl-[acyl-carrier-protein] hydrolase]EC3.1.2.15 [Ubiquitin thiolesterase]EC3.1.2.2 [Palmitoyl-CoA hydrolase]EC3.1.2.20 [Acyl-CoA hydrolase]EC3.1.2.22 [Palmitoyl-protein hydrolase]EC3.1.2.4 [3-hydroxyisobutyryl-CoA hydrolase]EC3.1.2.6 [Hydroxyacylglutathione hydrolase]EC3.1.21.- [NA]EC3.1.21.1 [Deoxyribonuclease I]

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EC3.1.21.2 [Deoxyribonuclease IV (phage-T(4)-induced)]EC3.1.21.3 [Type I site-specific deoxyribonuclease]EC3.1.21.4 [Type II site-specific deoxyribonuclease]EC3.1.21.5 [Type III site-specific deoxyribonuclease]EC3.1.21.7 [Deoxyribonuclease V]EC3.1.22.- [NA]EC3.1.22.1 [Deoxyribonuclease II]EC3.1.22.4 [Crossover junction endodeoxyribonuclease]EC3.1.25.- [NA]EC3.1.26.- [NA]EC3.1.26.11 [Ribonuclease Z]EC3.1.26.12 [Ribonuclease E]EC3.1.26.3 [Ribonuclease III]EC3.1.26.4 [Ribonuclease H]EC3.1.26.5 [Ribonuclease P]EC3.1.26.8 [Ribonuclease M5]EC3.1.27.- [NA]EC3.1.27.3 [Ribonuclease T(1)]EC3.1.27.6 [Enterobacter ribonuclease]EC3.1.27.9 [tRNA-intron endonuclease]EC3.1.3.- [NA]EC3.1.3.1 [Alkaline phosphatase]EC3.1.3.10 [Glucose-1-phosphatase]EC3.1.3.11 [Fructose-bisphosphatase]EC3.1.3.12 [Trehalose-phosphatase]EC3.1.3.15 [Histidinol-phosphatase]EC3.1.3.16 [Phosphoprotein phosphatase]EC3.1.3.18 [Phosphoglycolate phosphatase]EC3.1.3.2 [Acid phosphatase]EC3.1.3.23 [Sugar-phosphatase]EC3.1.3.25 [Inositol-phosphate phosphatase]EC3.1.3.26 [4-phytase]EC3.1.3.27 [Phosphatidylglycerophosphatase]EC3.1.3.3 [Phosphoserine phosphatase]EC3.1.3.36 [Phosphoinositide 5-phosphatase]EC3.1.3.37 [Sedoheptulose-bisphosphatase]EC3.1.3.4 [Phosphatidate phosphatase]EC3.1.3.41 [4-nitrophenylphosphatase]EC3.1.3.45 [3-deoxy-manno-octulosonate-8-phosphatase]EC3.1.3.46 [Fructose-2,6-bisphosphate 2-phosphatase]EC3.1.3.48 [Protein-tyrosine-phosphatase]EC3.1.3.5 [5'-nucleotidase]EC3.1.3.56 [Inositol-polyphosphate 5-phosphatase]EC3.1.3.57 [Inositol-1,4-bisphosphate 1-phosphatase]EC3.1.3.6 [3'-nucleotidase]EC3.1.3.62 [Multiple inositol-polyphosphate phosphatase]

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EC3.1.3.68 [2-deoxyglucose-6-phosphatase]EC3.1.3.7 [3'(2'),5'-bisphosphate nucleotidase]EC3.1.3.70 [Mannosyl-3-phosphoglycerate phosphatase]EC3.1.3.71 [2-phosphosulfolactate phosphatase]EC3.1.3.73 [Alpha-ribazole phosphatase]EC3.1.3.77 [Acireductone synthase]EC3.1.3.78 [Phosphatidylinositol-4,5-bisphosphate 4-phosphatase]EC3.1.3.8 [3-phytase]EC3.1.3.9 [Glucose-6-phosphatase]EC3.1.30.- [NA]EC3.1.31.1 [Micrococcal nuclease]EC3.1.4.- [NA]EC3.1.4.1 [Phosphodiesterase I]EC3.1.4.11 [Phosphoinositide phospholipase C]EC3.1.4.12 [Sphingomyelin phosphodiesterase]EC3.1.4.14 [[Acyl-carrier-protein] phosphodiesterase]EC3.1.4.16 [2',3'-cyclic-nucleotide 2'-phosphodiesterase]EC3.1.4.17 [3',5'-cyclic-nucleotide phosphodiesterase]EC3.1.4.3 [Phospholipase C]EC3.1.4.35 [3',5'-cyclic-GMP phosphodiesterase]EC3.1.4.37 [2',3'-cyclic-nucleotide 3'-phosphodiesterase]EC3.1.4.4 [Phospholipase D]EC3.1.4.45 [N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase]EC3.1.4.46 [Glycerophosphodiester phosphodiesterase]EC3.1.4.52 [Cyclic-guanylate-specific phosphodiesterase]EC3.1.4.53 [3',5'-cyclic-AMP phosphodiesterase]EC3.1.5.1 [dGTPase]EC3.1.6.- [NA]EC3.1.6.1 [Arylsulfatase]EC3.1.6.12 [N-acetylgalactosamine-4-sulfatase]EC3.1.6.13 [Iduronate-2-sulfatase]EC3.1.6.14 [N-acetylglucosamine-6-sulfatase]EC3.1.6.4 [N-acetylgalactosamine-6-sulfatase]EC3.1.6.6 [Choline-sulfatase]EC3.1.6.8 [Cerebroside-sulfatase]EC3.1.7.2 [Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase]EC3.1.8.1 [Aryldialkylphosphatase]EC3.11.1.1 [Phosphonoacetaldehyde hydrolase]EC3.11.1.2 [Phosphonoacetate hydrolase]EC3.2.-.- [NA]EC3.2.1.- [NA]EC3.2.1.1 [Alpha-amylase]EC3.2.1.10 [Oligo-1,6-glucosidase]EC3.2.1.101 [Mannan endo-1,6-alpha-mannosidase]EC3.2.1.106 [Mannosyl-oligosaccharide glucosidase]EC3.2.1.11 [Dextranase]

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EC3.2.1.113 [Mannosyl-oligosaccharide 1,2-alpha-mannosidase]EC3.2.1.114 [Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]EC3.2.1.122 [Maltose-6'-phosphate glucosidase]EC3.2.1.133 [Glucan 1,4-alpha-maltohydrolase]EC3.2.1.135 [Neopullulanase]EC3.2.1.139 [Alpha-glucuronidase]EC3.2.1.14 [Chitinase]EC3.2.1.141 [4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehalohydrolase]EC3.2.1.143 [Poly(ADP-ribose) glycohydrolase]EC3.2.1.15 [Polygalacturonase]EC3.2.1.17 [Lysozyme]EC3.2.1.18 [Exo-alpha-sialidase]EC3.2.1.20 [Alpha-glucosidase]EC3.2.1.21 [Beta-glucosidase]EC3.2.1.22 [Alpha-galactosidase]EC3.2.1.23 [Beta-galactosidase]EC3.2.1.24 [Alpha-mannosidase]EC3.2.1.25 [Beta-mannosidase]EC3.2.1.26 [Beta-fructofuranosidase]EC3.2.1.28 [Alpha,alpha-trehalase]EC3.2.1.3 [Glucan 1,4-alpha-glucosidase]EC3.2.1.31 [Beta-glucuronidase]EC3.2.1.33 [Amylo-alpha-1,6-glucosidase]EC3.2.1.35 [Hyaluronoglucosaminidase]EC3.2.1.37 [Xylan 1,4-beta-xylosidase]EC3.2.1.39 [Glucan endo-1,3-beta-D-glucosidase]EC3.2.1.4 [Cellulase]EC3.2.1.40 [Alpha-L-rhamnosidase]EC3.2.1.41 [Pullulanase]EC3.2.1.45 [Glucosylceramidase]EC3.2.1.46 [Galactosylceramidase]EC3.2.1.50 [Alpha-N-acetylglucosaminidase]EC3.2.1.51 [Alpha-L-fucosidase]EC3.2.1.52 [Beta-N-acetylhexosaminidase]EC3.2.1.54 [Cyclomaltodextrinase]EC3.2.1.55 [Alpha-N-arabinofuranosidase]EC3.2.1.58 [Glucan 1,3-beta-glucosidase]EC3.2.1.6 [Endo-1,3(4)-beta-glucanase]EC3.2.1.65 [Levanase]EC3.2.1.67 [Galacturan 1,4-alpha-galacturonidase]EC3.2.1.68 [Isoamylase]EC3.2.1.70 [Glucan 1,6-alpha-glucosidase]EC3.2.1.73 [Licheninase]EC3.2.1.76 [L-iduronidase]EC3.2.1.78 [Mannan endo-1,4-beta-mannosidase]EC3.2.1.8 [Endo-1,4-beta-xylanase]

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EC3.2.1.80 [Fructan beta-fructosidase]EC3.2.1.81 [Beta-agarase]EC3.2.1.84 [Glucan 1,3-alpha-glucosidase]EC3.2.1.85 [6-phospho-beta-galactosidase]EC3.2.1.86 [6-phospho-beta-glucosidase]EC3.2.1.89 [Arabinogalactan endo-1,4-beta-galactosidase]EC3.2.1.91 [Cellulose 1,4-beta-cellobiosidase]EC3.2.1.93 [Alpha,alpha-phosphotrehalase]EC3.2.1.96 [Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase]EC3.2.1.99 [Arabinan endo-1,5-alpha-L-arabinosidase]EC3.2.2.- [NA]EC3.2.2.1 [Purine nucleosidase]EC3.2.2.20 [DNA-3-methyladenine glycosylase I]EC3.2.2.21 [DNA-3-methyladenine glycosylase II]EC3.2.2.23 [DNA-formamidopyrimidine glycosylase]EC3.2.2.4 [AMP nucleosidase]EC3.2.2.5 [NAD(+) nucleosidase]EC3.2.2.8 [Ribosylpyrimidine nucleosidase]EC3.2.2.9 [Adenosylhomocysteine nucleosidase]EC3.3.1.1 [Adenosylhomocysteinase]EC3.3.2.1 [Isochorismatase]EC3.3.2.10 [Soluble epoxide hydrolase]EC3.3.2.6 [Leukotriene-A(4) hydrolase]EC3.4.-.- [NA]EC3.4.11.- [NA]EC3.4.11.1 [Leucyl aminopeptidase]EC3.4.11.10 [Bacterial leucyl aminopeptidase]EC3.4.11.15 [Aminopeptidase Y]EC3.4.11.18 [Methionyl aminopeptidase]EC3.4.11.19 [D-stereospecific aminopeptidase]EC3.4.11.2 [Membrane alanyl aminopeptidase]EC3.4.11.21 [Aspartyl aminopeptidase]EC3.4.11.23 [PepB aminopeptidase]EC3.4.11.4 [Tripeptide aminopeptidase]EC3.4.11.5 [Prolyl aminopeptidase]EC3.4.11.7 [Glutamyl aminopeptidase]EC3.4.11.9 [Xaa-Pro aminopeptidase]EC3.4.13.- [NA]EC3.4.13.19 [Membrane dipeptidase]EC3.4.13.21 [Dipeptidase E]EC3.4.13.3 [Xaa-His dipeptidase]EC3.4.13.9 [Xaa-Pro dipeptidase]EC3.4.14.- [NA]EC3.4.14.1 [Dipeptidyl-peptidase I]EC3.4.14.10 [Tripeptidyl-peptidase II]EC3.4.14.11 [Xaa-Pro dipeptidyl-peptidase]

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EC3.4.14.2 [Dipeptidyl-peptidase II]EC3.4.14.4 [Dipeptidyl-peptidase III]EC3.4.14.5 [Dipeptidyl-peptidase IV]EC3.4.14.9 [Tripeptidyl-peptidase I]EC3.4.15.1 [Peptidyl-dipeptidase A]EC3.4.15.5 [Peptidyl-dipeptidase Dcp]EC3.4.15.6 [Cyanophycinase]EC3.4.16.- [NA]EC3.4.16.2 [Lysosomal Pro-Xaa carboxypeptidase]EC3.4.16.4 [Serine-type D-Ala-D-Ala carboxypeptidase]EC3.4.16.5 [Carboxypeptidase C]EC3.4.16.6 [Carboxypeptidase D]EC3.4.17.- [NA]EC3.4.17.11 [Glutamate carboxypeptidase]EC3.4.17.13 [Muramoyltetrapeptide carboxypeptidase]EC3.4.17.15 [Carboxypeptidase A2]EC3.4.17.19 [Carboxypeptidase Taq]EC3.4.17.2 [Carboxypeptidase B]EC3.4.17.21 [Glutamate carboxypeptidase II]EC3.4.17.3 [Lysine carboxypeptidase]EC3.4.17.4 [Gly-Xaa carboxypeptidase]EC3.4.19.- [NA]EC3.4.19.1 [Acylaminoacyl-peptidase]EC3.4.19.11 [Gamma-D-glutamyl-meso-diaminopimelate peptidase]EC3.4.19.12 [Ubiquitinyl hydrolase 1]EC3.4.19.3 [Pyroglutamyl-peptidase I]EC3.4.19.5 [Beta-aspartyl-peptidase]EC3.4.19.6 [Pyroglutamyl-peptidase II]EC3.4.21.- [NA]EC3.4.21.10 [Acrosin]EC3.4.21.102 [C-terminal processing peptidase]EC3.4.21.104 [Mannan-binding lectin-associated serine protease-2]EC3.4.21.105 [Rhomboid protease]EC3.4.21.107 [Peptidase Do]EC3.4.21.116 [SpoIVB peptidase]EC3.4.21.19 [Glutamyl endopeptidase]EC3.4.21.26 [Prolyl oligopeptidase]EC3.4.21.36 [Pancreatic elastase]EC3.4.21.45 [Complement factor I]EC3.4.21.50 [Lysyl endopeptidase]EC3.4.21.53 [Endopeptidase La]EC3.4.21.6 [Coagulation factor Xa]EC3.4.21.62 [Subtilisin]EC3.4.21.69 [Protein C (activated)]EC3.4.21.72 [IgA-specific serine endopeptidase]EC3.4.21.75 [Furin]

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EC3.4.21.83 [Oligopeptidase B]EC3.4.21.88 [Repressor lexA]EC3.4.21.89 [Signal peptidase I]EC3.4.21.9 [Enteropeptidase]EC3.4.21.92 [Endopeptidase Clp]EC3.4.21.96 [Lactocepin]EC3.4.22.- [NA]EC3.4.22.1 [Cathepsin B]EC3.4.22.10 [Streptopain]EC3.4.22.15 [Cathepsin L]EC3.4.22.34 [Legumain]EC3.4.22.36 [Caspase-1]EC3.4.22.37 [Gingipain R]EC3.4.22.40 [Bleomycin hydrolase]EC3.4.22.48 [Staphopain]EC3.4.22.49 [Separase]EC3.4.22.55 [Caspase-2]EC3.4.22.8 [Clostripain]EC3.4.23.- [NA]EC3.4.23.25 [Saccharopepsin]EC3.4.23.36 [Signal peptidase II]EC3.4.23.4 [Chymosin]EC3.4.23.40 [Phytepsin]EC3.4.23.41 [Yapsin 1]EC3.4.23.43 [Prepilin peptidase]EC3.4.23.46 [Memapsin 2]EC3.4.23.49 [Omptin]EC3.4.23.5 [Cathepsin D]EC3.4.24.- [NA]EC3.4.24.11 [Neprilysin]EC3.4.24.13 [IgA-specific metalloendopeptidase]EC3.4.24.14 [Procollagen N-endopeptidase]EC3.4.24.16 [Neurolysin]EC3.4.24.17 [Stromelysin 1]EC3.4.24.18 [Meprin A]EC3.4.24.20 [Peptidyl-Lys metalloendopeptidase]EC3.4.24.21 [Astacin]EC3.4.24.25 [Vibriolysin]EC3.4.24.28 [Bacillolysin]EC3.4.24.3 [Microbial collagenase]EC3.4.24.34 [Neutrophil collagenase]EC3.4.24.36 [Leishmanolysin]EC3.4.24.40 [Serralysin]EC3.4.24.55 [Pitrilysin]EC3.4.24.56 [Insulysin]EC3.4.24.57 [O-sialoglycoprotein endopeptidase]

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EC3.4.24.59 [Mitochondrial intermediate peptidase]EC3.4.24.61 [Nardilysin]EC3.4.24.64 [Mitochondrial processing peptidase]EC3.4.24.69 [Bontoxilysin]EC3.4.24.70 [Oligopeptidase A]EC3.4.24.71 [Endothelin-converting enzyme 1]EC3.4.24.75 [Lysostaphin]EC3.4.24.78 [GPR endopeptidase]EC3.4.24.79 [Pappalysin-1]EC3.4.24.81 [ADAM10 endopeptidase]EC3.4.24.84 [Ste24 endopeptidase]EC3.4.25.- [NA]EC3.4.25.1 [Proteasome endopeptidase complex]EC3.4.99.- [NA]EC3.5.-.- [NA]EC3.5.1.- [NA]EC3.5.1.1 [Asparaginase]EC3.5.1.10 [Formyltetrahydrofolate deformylase]EC3.5.1.11 [Penicillin amidase]EC3.5.1.14 [Aminoacylase]EC3.5.1.15 [Aspartoacylase]EC3.5.1.16 [Acetylornithine deacetylase]EC3.5.1.18 [Succinyl-diaminopimelate desuccinylase]EC3.5.1.19 [Nicotinamidase]EC3.5.1.2 [Glutaminase]EC3.5.1.23 [Ceramidase]EC3.5.1.24 [Choloylglycine hydrolase]EC3.5.1.25 [N-acetylglucosamine-6-phosphate deacetylase]EC3.5.1.26 [N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase]EC3.5.1.28 [N-acetylmuramoyl-L-alanine amidase]EC3.5.1.32 [Hippurate hydrolase]EC3.5.1.4 [Amidase]EC3.5.1.41 [Chitin deacetylase]EC3.5.1.44 [Protein-glutamine glutaminase]EC3.5.1.46 [6-aminohexanoate-dimer hydrolase]EC3.5.1.47 [N-acetyldiaminopimelate deacetylase]EC3.5.1.49 [Formamidase]EC3.5.1.5 [Urease]EC3.5.1.52 [Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase]EC3.5.1.53 [N-carbamoylputrescine amidase]EC3.5.1.54 [Allophanate hydrolase]EC3.5.1.69 [Glycosphingolipid deacylase]EC3.5.1.77 [N-carbamoyl-D-amino-acid hydrolase]EC3.5.1.78 [Glutathionylspermidine amidase]EC3.5.1.81 [N-acyl-D-amino-acid deacylase]EC3.5.1.82 [N-acyl-D-glutamate deacylase]

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EC3.5.1.87 [N-carbamoyl-L-amino-acid hydrolase]EC3.5.1.88 [Peptide deformylase]EC3.5.1.89 [N-acetylglucosaminylphosphatidylinositol deacetylase]EC3.5.1.90 [Adenosylcobinamide hydrolase]EC3.5.1.94 [Gamma-glutamyl-gamma-aminobutyrate hydrolase]EC3.5.1.96 [Succinylglutamate desuccinylase]EC3.5.1.98 [Histone deacetylase]EC3.5.2.10 [Creatininase]EC3.5.2.14 [N-methylhydantoinase (ATP-hydrolyzing)]EC3.5.2.17 [Hydroxyisourate hydrolase]EC3.5.2.2 [Dihydropyrimidinase]EC3.5.2.3 [Dihydroorotase]EC3.5.2.5 [Allantoinase]EC3.5.2.6 [Beta-lactamase]EC3.5.2.7 [Imidazolonepropionase]EC3.5.2.9 [5-oxoprolinase (ATP-hydrolyzing)]EC3.5.3.1 [Arginase]EC3.5.3.11 [Agmatinase]EC3.5.3.12 [Agmatine deiminase]EC3.5.3.15 [Protein-arginine deiminase]EC3.5.3.18 [Dimethylargininase]EC3.5.3.19 [Ureidoglycolate hydrolase]EC3.5.3.23 [N-succinylarginine dihydrolase]EC3.5.3.4 [Allantoicase]EC3.5.3.6 [Arginine deiminase]EC3.5.3.7 [Guanidinobutyrase]EC3.5.3.8 [Formimidoylglutamase]EC3.5.3.9 [Allantoate deiminase]EC3.5.4.- [NA]EC3.5.4.1 [Cytosine deaminase]EC3.5.4.10 [IMP cyclohydrolase]EC3.5.4.12 [dCMP deaminase]EC3.5.4.13 [dCTP deaminase]EC3.5.4.16 [GTP cyclohydrolase I]EC3.5.4.19 [Phosphoribosyl-AMP cyclohydrolase]EC3.5.4.2 [Adenine deaminase]EC3.5.4.23 [Blasticidin-S deaminase]EC3.5.4.25 [GTP cyclohydrolase II]EC3.5.4.27 [Methenyltetrahydromethanopterin cyclohydrolase]EC3.5.4.28 [S-adenosylhomocysteine deaminase]EC3.5.4.29 [GTP cyclohydrolase IIa]EC3.5.4.3 [Guanine deaminase]EC3.5.4.4 [Adenosine deaminase]EC3.5.4.5 [Cytidine deaminase]EC3.5.4.6 [AMP deaminase]EC3.5.4.9 [Methenyltetrahydrofolate cyclohydrolase]

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EC3.5.5.1 [Nitrilase]EC3.5.5.4 [Cyanoalanine nitrilase]EC3.5.99.2 [Thiaminase]EC3.5.99.3 [Hydroxydechloroatrazine ethylaminohydrolase]EC3.5.99.4 [N-isopropylammelide isopropylaminohydrolase]EC3.5.99.6 [Glucosamine-6-phosphate deaminase]EC3.5.99.7 [1-aminocyclopropane-1-carboxylate deaminase]EC3.6.-.- [NA]EC3.6.1.- [NA]EC3.6.1.1 [Inorganic diphosphatase]EC3.6.1.11 [Exopolyphosphatase]EC3.6.1.13 [ADP-ribose diphosphatase]EC3.6.1.15 [Nucleoside-triphosphatase]EC3.6.1.16 [CDP-glycerol diphosphatase]EC3.6.1.17 [Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)]EC3.6.1.19 [Nucleoside-triphosphate diphosphatase]EC3.6.1.22 [NAD(+) diphosphatase]EC3.6.1.23 [dUTP diphosphatase]EC3.6.1.26 [CDP-diacylglycerol diphosphatase]EC3.6.1.27 [Undecaprenyl-diphosphatase]EC3.6.1.3 [Adenosinetriphosphatase]EC3.6.1.31 [Phosphoribosyl-ATP diphosphatase]EC3.6.1.40 [Guanosine-5'-triphosphate,3'-diphosphate diphosphatase]EC3.6.1.41 [Bis(5'-nucleosyl)-tetraphosphatase (symmetrical)]EC3.6.1.42 [Guanosine-diphosphatase]EC3.6.1.43 [Dolichyldiphosphatase]EC3.6.1.45 [UDP-sugar diphosphatase]EC3.6.1.5 [Apyrase]EC3.6.1.53 [Mn(2+)-dependent ATP-ribose/CDP-alcohol diphosphatase]EC3.6.1.6 [Nucleoside-diphosphatase]EC3.6.1.7 [Acylphosphatase]EC3.6.1.9 [Nucleotide diphosphatase]EC3.6.3.- [NA]EC3.6.3.1 [Phospholipid-translocating ATPase]EC3.6.3.12 [Potassium-transporting ATPase]EC3.6.3.14 [H(+)-transporting two-sector ATPase]EC3.6.3.16 [Arsenite-transporting ATPase]EC3.6.3.17 [Monosaccharide-transporting ATPase]EC3.6.3.19 [Maltose-transporting ATPase]EC3.6.3.2 [Magnesium-importing ATPase]EC3.6.3.20 [Glycerol-3-phosphate-transporting ATPase]EC3.6.3.21 [Polar-amino-acid-transporting ATPase]EC3.6.3.24 [Nickel-transporting ATPase]EC3.6.3.25 [Sulfate-transporting ATPase]EC3.6.3.27 [Phosphate-transporting ATPase]EC3.6.3.29 [Molybdate-transporting ATPase]

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EC3.6.3.3 [Cadmium-exporting ATPase]EC3.6.3.30 [Fe(3+)-transporting ATPase]EC3.6.3.31 [Polyamine-transporting ATPase]EC3.6.3.32 [Quaternary-amine-transporting ATPase]EC3.6.3.33 [Vitamin B12-transporting ATPase]EC3.6.3.34 [Iron-chelate-transporting ATPase]EC3.6.3.4 [Copper-exporting ATPase]EC3.6.3.40 [Teichoic-acid-transporting ATPase]EC3.6.3.41 [Heme-transporting ATPase]EC3.6.3.5 [Zinc-exporting ATPase]EC3.6.3.6 [Proton-exporting ATPase]EC3.6.3.8 [Calcium-transporting ATPase]EC3.6.3.9 [Sodium/potassium-exchanging ATPase]EC3.6.4.1 [Myosin ATPase]EC3.6.4.4 [Plus-end-directed kinesin ATPase]EC3.6.4.6 [Vesicle-fusing ATPase]EC3.6.5.- [NA]EC3.6.5.3 [Protein-synthesizing GTPase]EC3.6.5.5 [Dynamin GTPase]EC3.7.1.- [NA]EC3.7.1.2 [Fumarylacetoacetase]EC3.7.1.3 [Kynureninase]EC3.8.1.- [NA]EC3.8.1.1 [Alkylhalidase]EC3.8.1.2 [(S)-2-haloacid dehalogenase]EC3.8.1.5 [Haloalkane dehalogenase]EC3.8.1.8 [Atrazine chlorohydrolase]EC4.-.-.- [NA]EC4.1.-.- [NA]EC4.1.1.- [NA]EC4.1.1.1 [Pyruvate decarboxylase]EC4.1.1.11 [Aspartate 1-decarboxylase]EC4.1.1.12 [Aspartate 4-decarboxylase]EC4.1.1.15 [Glutamate decarboxylase]EC4.1.1.17 [Ornithine decarboxylase]EC4.1.1.18 [Lysine decarboxylase]EC4.1.1.19 [Arginine decarboxylase]EC4.1.1.2 [Oxalate decarboxylase]EC4.1.1.20 [Diaminopimelate decarboxylase]EC4.1.1.21 [Phosphoribosylaminoimidazole carboxylase]EC4.1.1.22 [Histidine decarboxylase]EC4.1.1.23 [Orotidine-5'-phosphate decarboxylase]EC4.1.1.25 [Tyrosine decarboxylase]EC4.1.1.28 [Aromatic-L-amino-acid decarboxylase]EC4.1.1.3 [Oxaloacetate decarboxylase]EC4.1.1.31 [Phosphoenolpyruvate carboxylase]

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EC4.1.1.32 [Phosphoenolpyruvate carboxykinase (GTP)]EC4.1.1.33 [Diphosphomevalonate decarboxylase]EC4.1.1.36 [Phosphopantothenoylcysteine decarboxylase]EC4.1.1.37 [Uroporphyrinogen decarboxylase]EC4.1.1.39 [Ribulose-bisphosphate carboxylase]EC4.1.1.41 [Methylmalonyl-CoA decarboxylase]EC4.1.1.44 [4-carboxymuconolactone decarboxylase]EC4.1.1.45 [Aminocarboxymuconate-semialdehyde decarboxylase]EC4.1.1.47 [Tartronate-semialdehyde synthase]EC4.1.1.48 [Indole-3-glycerol-phosphate synthase]EC4.1.1.49 [Phosphoenolpyruvate carboxykinase (ATP)]EC4.1.1.5 [Acetolactate decarboxylase]EC4.1.1.50 [Adenosylmethionine decarboxylase]EC4.1.1.65 [Phosphatidylserine decarboxylase]EC4.1.1.68 [5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase]EC4.1.1.7 [Benzoylformate decarboxylase]EC4.1.1.70 [Glutaconyl-CoA decarboxylase]EC4.1.1.73 [Tartrate decarboxylase]EC4.1.1.79 [Sulfopyruvate decarboxylase]EC4.1.1.8 [Oxalyl-CoA decarboxylase]EC4.1.1.81 [Threonine-phosphate decarboxylase]EC4.1.1.82 [Phosphonopyruvate decarboxylase]EC4.1.1.85 [3-dehydro-L-gulonate-6-phosphate decarboxylase]EC4.1.1.9 [Malonyl-CoA decarboxylase]EC4.1.2.- [NA]EC4.1.2.13 [Fructose-bisphosphate aldolase]EC4.1.2.14 [2-dehydro-3-deoxy-phosphogluconate aldolase]EC4.1.2.17 [L-fuculose-phosphate aldolase]EC4.1.2.19 [Rhamnulose-1-phosphate aldolase]EC4.1.2.20 [2-dehydro-3-deoxyglucarate aldolase]EC4.1.2.21 [2-dehydro-3-deoxy-6-phosphogalactonate aldolase]EC4.1.2.22 [Fructose-6-phosphate phosphoketolase]EC4.1.2.25 [Dihydroneopterin aldolase]EC4.1.2.27 [Sphinganine-1-phosphate aldolase]EC4.1.2.4 [Deoxyribose-phosphate aldolase]EC4.1.2.40 [Tagatose-bisphosphate aldolase]EC4.1.2.43 [3-hexulose-6-phosphate synthase]EC4.1.2.5 [Threonine aldolase]EC4.1.2.9 [Phosphoketolase]EC4.1.3.- [NA]EC4.1.3.1 [Isocitrate lyase]EC4.1.3.16 [4-hydroxy-2-oxoglutarate aldolase]EC4.1.3.17 [4-hydroxy-4-methyl-2-oxoglutarate aldolase]EC4.1.3.27 [Anthranilate synthase]EC4.1.3.3 [N-acetylneuraminate lyase]EC4.1.3.30 [Methylisocitrate lyase]

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EC4.1.3.34 [Citryl-CoA lyase]EC4.1.3.36 [Naphthoate synthase]EC4.1.3.38 [Aminodeoxychorismate lyase]EC4.1.3.39 [4-hydroxy-2-oxovalerate aldolase]EC4.1.3.4 [Hydroxymethylglutaryl-CoA lyase]EC4.1.3.40 [Chorismate lyase]EC4.1.3.6 [Citrate (pro-3S)-lyase]EC4.1.99.- [NA]EC4.1.99.1 [Tryptophanase]EC4.1.99.12 [3,4-dihydroxy-2-butanone-4-phosphate synthase]EC4.1.99.2 [Tyrosine phenol-lyase]EC4.1.99.3 [Deoxyribodipyrimidine photo-lyase]EC4.2.-.- [NA]EC4.2.1.- [NA]EC4.2.1.1 [Carbonate dehydratase]EC4.2.1.10 [3-dehydroquinate dehydratase]EC4.2.1.104 [Cyanase]EC4.2.1.109 [Methylthioribulose 1-phosphate dehydratase]EC4.2.1.11 [Phosphopyruvate hydratase]EC4.2.1.113 [o-succinylbenzoate synthase]EC4.2.1.12 [Phosphogluconate dehydratase]EC4.2.1.17 [Enoyl-CoA hydratase]EC4.2.1.18 [Methylglutaconyl-CoA hydratase]EC4.2.1.19 [Imidazoleglycerol-phosphate dehydratase]EC4.2.1.2 [Fumarate hydratase]EC4.2.1.20 [Tryptophan synthase]EC4.2.1.22 [Cystathionine beta-synthase]EC4.2.1.24 [Porphobilinogen synthase]EC4.2.1.28 [Propanediol dehydratase]EC4.2.1.3 [Aconitate hydratase]EC4.2.1.30 [Glycerol dehydratase]EC4.2.1.32 [L(+)-tartrate dehydratase]EC4.2.1.33 [3-isopropylmalate dehydratase]EC4.2.1.35 [(R)-2-methylmalate dehydratase]EC4.2.1.39 [Gluconate dehydratase]EC4.2.1.40 [Glucarate dehydratase]EC4.2.1.41 [5-dehydro-4-deoxyglucarate dehydratase]EC4.2.1.42 [Galactarate dehydratase]EC4.2.1.44 [Myo-inosose-2 dehydratase]EC4.2.1.45 [CDP-glucose 4,6-dehydratase]EC4.2.1.46 [dTDP-glucose 4,6-dehydratase]EC4.2.1.47 [GDP-mannose 4,6-dehydratase]EC4.2.1.49 [Urocanate hydratase]EC4.2.1.51 [Prephenate dehydratase]EC4.2.1.52 [Dihydrodipicolinate synthase]EC4.2.1.55 [3-hydroxybutyryl-CoA dehydratase]

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EC4.2.1.6 [Galactonate dehydratase]EC4.2.1.60 [3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase]EC4.2.1.7 [Altronate dehydratase]EC4.2.1.70 [Pseudouridylate synthase]EC4.2.1.75 [Uroporphyrinogen-III synthase]EC4.2.1.76 [UDP-glucose 4,6-dehydratase]EC4.2.1.79 [2-methylcitrate dehydratase]EC4.2.1.8 [Mannonate dehydratase]EC4.2.1.80 [2-oxopent-4-enoate hydratase]EC4.2.1.9 [Dihydroxy-acid dehydratase]EC4.2.1.90 [L-rhamnonate dehydratase]EC4.2.1.96 [4a-hydroxytetrahydrobiopterin dehydratase]EC4.2.2.- [NA]EC4.2.2.1 [Hyaluronate lyase]EC4.2.2.17 [Inulin fructotransferase (DFA-I-forming)]EC4.2.2.2 [Pectate lyase]EC4.2.2.20 [Chondroitin-sulfate-ABC endolyase]EC4.2.2.21 [Chondroitin-sulfate-ABC exolyase]EC4.2.2.3 [Poly(beta-D-mannuronate) lyase]EC4.2.2.6 [Oligogalacturonide lyase]EC4.2.2.9 [Pectate disaccharide-lyase]EC4.2.3.1 [Threonine synthase]EC4.2.3.12 [6-pyruvoyltetrahydropterin synthase]EC4.2.3.3 [Methylglyoxal synthase]EC4.2.3.4 [3-dehydroquinate synthase]EC4.2.3.5 [Chorismate synthase]EC4.2.99.- [NA]EC4.2.99.18 [DNA-(apurinic or apyrimidinic site) lyase]EC4.2.99.20 [2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase]EC4.3.-.- [NA]EC4.3.1.1 [Aspartate ammonia-lyase]EC4.3.1.12 [Ornithine cyclodeaminase]EC4.3.1.15 [Diaminopropionate ammonia-lyase]EC4.3.1.17 [L-serine ammonia-lyase]EC4.3.1.18 [D-serine ammonia-lyase]EC4.3.1.19 [Threonine ammonia-lyase]EC4.3.1.2 [Methylaspartate ammonia-lyase]EC4.3.1.3 [Histidine ammonia-lyase]EC4.3.1.4 [Formimidoyltetrahydrofolate cyclodeaminase]EC4.3.1.7 [Ethanolamine ammonia-lyase]EC4.3.2.1 [Argininosuccinate lyase]EC4.3.2.2 [Adenylosuccinate lyase]EC4.4.1.- [NA]EC4.4.1.1 [Cystathionine gamma-lyase]EC4.4.1.11 [Methionine gamma-lyase]EC4.4.1.15 [D-cysteine desulfhydrase]

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EC4.4.1.16 [Selenocysteine lyase]EC4.4.1.19 [Phosphosulfolactate synthase]EC4.4.1.21 [S-ribosylhomocysteine lyase]EC4.4.1.22 [S-(hydroxymethyl)glutathione synthase]EC4.4.1.5 [Lactoylglutathione lyase]EC4.4.1.8 [Cystathionine beta-lyase]EC4.6.1.- [NA]EC4.6.1.1 [Adenylate cyclase]EC4.6.1.12 [2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase]EC4.6.1.13 [Phosphatidylinositol diacylglycerol-lyase]EC4.6.1.2 [Guanylate cyclase]EC4.99.1.1 [Ferrochelatase]EC4.99.1.3 [Sirohydrochlorin cobaltochelatase]EC4.99.1.4 [Sirohydrochlorin ferrochelatase]EC5.-.-.- [NA]EC5.1.1.- [NA]EC5.1.1.1 [Alanine racemase]EC5.1.1.13 [Aspartate racemase]EC5.1.1.3 [Glutamate racemase]EC5.1.1.4 [Proline racemase]EC5.1.1.7 [Diaminopimelate epimerase]EC5.1.2.2 [Mandelate racemase]EC5.1.2.3 [3-hydroxybutyryl-CoA epimerase]EC5.1.3.- [NA]EC5.1.3.1 [Ribulose-phosphate 3-epimerase]EC5.1.3.10 [CDP-paratose 2-epimerase]EC5.1.3.13 [dTDP-4-dehydrorhamnose 3,5-epimerase]EC5.1.3.14 [UDP-N-acetylglucosamine 2-epimerase]EC5.1.3.18 [GDP-mannose 3,5-epimerase]EC5.1.3.19 [Chondroitin-glucuronate 5-epimerase]EC5.1.3.2 [UDP-glucose 4-epimerase]EC5.1.3.20 [ADP-glyceromanno-heptose 6-epimerase]EC5.1.3.22 [L-ribulose-5-phosphate 3-epimerase]EC5.1.3.23 [UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase]EC5.1.3.3 [Aldose 1-epimerase]EC5.1.3.4 [L-ribulose-5-phosphate 4-epimerase]EC5.1.3.8 [N-acylglucosamine 2-epimerase]EC5.1.3.9 [N-acylglucosamine-6-phosphate 2-epimerase]EC5.1.99.- [NA]EC5.1.99.1 [Methylmalonyl-CoA epimerase]EC5.1.99.4 [Alpha-methylacyl-CoA racemase]EC5.2.1.2 [Maleylacetoacetate isomerase]EC5.2.1.8 [Peptidylprolyl isomerase]EC5.3.1.- [NA]EC5.3.1.1 [Triose-phosphate isomerase]EC5.3.1.12 [Glucuronate isomerase]

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EC5.3.1.13 [Arabinose-5-phosphate isomerase]EC5.3.1.14 [L-rhamnose isomerase]EC5.3.1.16 [1-(5-phosphoribosyl)-5-]EC5.3.1.17 [4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase]EC5.3.1.22 [Hydroxypyruvate isomerase]EC5.3.1.23 [S-methyl-5-thioribose-1-phosphate isomerase]EC5.3.1.24 [Phosphoribosylanthranilate isomerase]EC5.3.1.25 [L-fucose isomerase]EC5.3.1.26 [Galactose-6-phosphate isomerase]EC5.3.1.27 [6-phospho-3-hexuloisomerase]EC5.3.1.4 [L-arabinose isomerase]EC5.3.1.5 [Xylose isomerase]EC5.3.1.6 [Ribose-5-phosphate isomerase]EC5.3.1.8 [Mannose-6-phosphate isomerase]EC5.3.1.9 [Glucose-6-phosphate isomerase]EC5.3.2.- [NA]EC5.3.2.1 [Phenylpyruvate tautomerase]EC5.3.3.- [NA]EC5.3.3.1 [Steroid Delta-isomerase]EC5.3.3.10 [5-carboxymethyl-2-hydroxymuconate Delta-isomerase]EC5.3.3.2 [Isopentenyl-diphosphate Delta-isomerase]EC5.3.3.5 [Cholestenol Delta-isomerase]EC5.3.3.8 [Dodecenoyl-CoA isomerase]EC5.3.4.1 [Protein disulfide-isomerase]EC5.3.99.- [NA]EC5.3.99.2 [Prostaglandin-D synthase]EC5.3.99.5 [Thromboxane-A synthase]EC5.4.1.2 [Precorrin-8X methylmutase]EC5.4.2.1 [Phosphoglycerate mutase]EC5.4.2.10 [Phosphoglucosamine mutase]EC5.4.2.2 [Phosphoglucomutase]EC5.4.2.3 [Phosphoacetylglucosamine mutase]EC5.4.2.6 [Beta-phosphoglucomutase]EC5.4.2.7 [Phosphopentomutase]EC5.4.2.8 [Phosphomannomutase]EC5.4.2.9 [Phosphoenolpyruvate mutase]EC5.4.3.2 [Lysine 2,3-aminomutase]EC5.4.3.3 [Beta-lysine 5,6-aminomutase]EC5.4.3.8 [Glutamate-1-semialdehyde 2,1-aminomutase]EC5.4.4.2 [Isochorismate synthase]EC5.4.99.- [NA]EC5.4.99.1 [Methylaspartate mutase]EC5.4.99.12 [tRNA-pseudouridine synthase I]EC5.4.99.15 [(1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase]EC5.4.99.16 [Maltose alpha-D-glucosyltransferase]EC5.4.99.17 [Squalene--hopene cyclase]

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EC5.4.99.18 [5-(carboxyamino)imidazole ribonucleotide mutase]EC5.4.99.2 [Methylmalonyl-CoA mutase]EC5.4.99.5 [Chorismate mutase]EC5.4.99.7 [Lanosterol synthase]EC5.4.99.8 [Cycloartenol synthase]EC5.4.99.9 [UDP-galactopyranose mutase]EC5.5.-.- [NA]EC5.5.1.4 [Inositol-3-phosphate synthase]EC5.5.1.7 [Chloromuconate cycloisomerase]EC5.99.1.- [NA]EC5.99.1.2 [DNA topoisomerase]EC5.99.1.3 [DNA topoisomerase (ATP-hydrolyzing)]EC6.-.-.- [NA]EC6.1.1.- [NA]EC6.1.1.1 [Tyrosine--tRNA ligase]EC6.1.1.10 [Methionine--tRNA ligase]EC6.1.1.11 [Serine--tRNA ligase]EC6.1.1.12 [Aspartate--tRNA ligase]EC6.1.1.13 [D-alanine--poly(phosphoribitol) ligase]EC6.1.1.14 [Glycine--tRNA ligase]EC6.1.1.15 [Proline--tRNA ligase]EC6.1.1.16 [Cysteine--tRNA ligase]EC6.1.1.17 [Glutamate--tRNA ligase]EC6.1.1.18 [Glutamine--tRNA ligase]EC6.1.1.19 [Arginine--tRNA ligase]EC6.1.1.2 [Tryptophan--tRNA ligase]EC6.1.1.20 [Phenylalanine--tRNA ligase]EC6.1.1.21 [Histidine--tRNA ligase]EC6.1.1.22 [Asparagine--tRNA ligase]EC6.1.1.23 [Aspartate--tRNA(Asn) ligase]EC6.1.1.24 [Glutamate--tRNA(Gln) ligase]EC6.1.1.27 [NA]EC6.1.1.3 [Threonine--tRNA ligase]EC6.1.1.4 [Leucine--tRNA ligase]EC6.1.1.5 [Isoleucine--tRNA ligase]EC6.1.1.6 [Lysine--tRNA ligase]EC6.1.1.7 [Alanine--tRNA ligase]EC6.1.1.9 [Valine--tRNA ligase]EC6.2.1.- [NA]EC6.2.1.1 [Acetate--CoA ligase]EC6.2.1.12 [4-coumarate--CoA ligase]EC6.2.1.13 [Acetate--CoA ligase (ADP-forming)]EC6.2.1.16 [Acetoacetate--CoA ligase]EC6.2.1.17 [Propionate--CoA ligase]EC6.2.1.19 [Long-chain-fatty-acid--luciferin-component ligase]EC6.2.1.20 [Long-chain-fatty-acid--[acyl-carrier-protein] ligase]

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EC6.2.1.22 [[Citrate (pro-3S)-lyase] ligase]EC6.2.1.26 [o-succinylbenzoate--CoA ligase]EC6.2.1.3 [Long-chain-fatty-acid--CoA ligase]EC6.2.1.30 [Phenylacetate--CoA ligase]EC6.2.1.34 [Trans-feruloyl-CoA synthase]EC6.2.1.5 [Succinate--CoA ligase (ADP-forming)]EC6.3.-.- [NA]EC6.3.1.- [NA]EC6.3.1.1 [Aspartate--ammonia ligase]EC6.3.1.10 [Adenosylcobinamide-phosphate synthase]EC6.3.1.11 [Glutamate--putrescine ligase]EC6.3.1.2 [Glutamate--ammonia ligase]EC6.3.1.5 [NAD(+) synthase]EC6.3.1.8 [Glutathionylspermidine synthase]EC6.3.2.- [NA]EC6.3.2.1 [Pantoate--beta-alanine ligase]EC6.3.2.10 [UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase]EC6.3.2.13 [UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase]EC6.3.2.17 [Tetrahydrofolate synthase]EC6.3.2.19 [Ubiquitin--protein ligase]EC6.3.2.2 [Glutamate--cysteine ligase]EC6.3.2.25 [Tubulin--tyrosine ligase]EC6.3.2.3 [Glutathione synthase]EC6.3.2.4 [D-alanine--D-alanine ligase]EC6.3.2.5 [Phosphopantothenate--cysteine ligase]EC6.3.2.6 [Phosphoribosylaminoimidazolesuccinocarboxamide synthase]EC6.3.2.7 [UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase]EC6.3.2.8 [UDP-N-acetylmuramate--L-alanine ligase]EC6.3.2.9 [UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase]EC6.3.3.1 [Phosphoribosylformylglycinamidine cyclo-ligase]EC6.3.3.2 [5-formyltetrahydrofolate cyclo-ligase]EC6.3.3.3 [Dethiobiotin synthase]EC6.3.4.- [NA]EC6.3.4.10 [Biotin--[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase]EC6.3.4.11 [Biotin--[methylcrotonoyl-CoA-carboxylase] ligase]EC6.3.4.13 [Phosphoribosylamine--glycine ligase]EC6.3.4.14 [Biotin carboxylase]EC6.3.4.15 [Biotin--[acetyl-CoA-carboxylase] ligase]EC6.3.4.18 [5-(carboxyamino)imidazole ribonucleotide synthase]EC6.3.4.2 [CTP synthase]EC6.3.4.3 [Formate--tetrahydrofolate ligase]EC6.3.4.4 [Adenylosuccinate synthase]EC6.3.4.5 [Argininosuccinate synthase]EC6.3.4.6 [Urea carboxylase]EC6.3.4.9 [Biotin--[methylmalonyl-CoA-carboxytransferase] ligase]EC6.3.5.1 [NAD(+) synthase (glutamine-hydrolyzing)]

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EC6.3.5.10 [Adenosylcobyric acid synthase (glutamine-hydrolyzing)]EC6.3.5.2 [GMP synthase (glutamine-hydrolyzing)]EC6.3.5.3 [Phosphoribosylformylglycinamidine synthase]EC6.3.5.4 [Asparagine synthase (glutamine-hydrolyzing)]EC6.3.5.5 [Carbamoyl-phosphate synthase (glutamine-hydrolyzing)]EC6.3.5.6 [Asparaginyl-tRNA synthase (glutamine-hydrolyzing)]EC6.3.5.7 [Glutaminyl-tRNA synthase (glutamine-hydrolyzing)]EC6.3.5.9 [Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolyzing)]EC6.4.1.- [NA]EC6.4.1.1 [Pyruvate carboxylase]EC6.4.1.2 [Acetyl-CoA carboxylase]EC6.4.1.3 [Propionyl-CoA carboxylase]EC6.4.1.4 [Methylcrotonoyl-CoA carboxylase]EC6.4.1.6 [Acetone carboxylase]EC6.5.1.- [NA]EC6.5.1.1 [DNA ligase (ATP)]EC6.5.1.2 [DNA ligase (NAD(+))]EC6.5.1.4 [RNA-3'-phosphate cyclase]EC6.6.1.1 [Magnesium chelatase]EC6.6.1.2 [Cobaltochelatase]

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Table S13. ShotgunFunctionalizeR analysis of EC-level changes in the metatranscriptome as a function of FMP strain introduction into mice and humans.

Mouse Mouse Mouse Human Human Human Humand15 vs d14d42multi vs d14d42single vs d14FMP1 vs Pre1FMP4 vs Pre1Post4 vs Pre1Post4 vs FMP40.924726 1.00699 0.947162 1.470588 1.119427 0.690122 0.6164960.791043 1.057895 NS 1.181147 NS NS NS0.869138 NS 0.711963 1.621205 1.258834 0.622278 0.4943290.809226 0.717741 0.795755 1.671788 1.183692 0.690878 0.5836641.072372 NS NS 1.60196 1.108653 NS 0.736279

NS NS NS NS NS NS NS0.859584 0.815137 0.69887 2.361293 NS NS NS1.642302 1.217842 NS 1.990633 NS NS NS

NS NS NS 1.390219 NS NS 0.540495NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 1.902331 NS 0.657898 0.6670911.216084 NS 1.536817 1.682994 NS 0.536429 0.50343

NS NS NS 1.830942 NS 0.384458 NSNS NS NS NS NS NS NSNS NS 0.508097 4.428289 1.356652 1.140136 NS1.241047 1.114296 NS 1.753246 1.146586 0.641782 0.5597341.556681 0.853543 NS NS NS 0.473591 0.426927

NS NS 1.529585 1.573866 1.083307 0.622186 0.57434NS NS NS NS 1.574018 NS 0.364208NS NS NS NS NS NS NSNS 0.791 NS 1.823047 1.333267 NS 0.4714271.317347 1.40308 1.605829 1.340215 1.114736 NS 0.649676

NS NS NS NS NS NS NSNS 0.549737 0.614537 NS NS NS NSNS NS NS 1.470013 1.454563 NS 0.505761NS NS NS 0.276473 NS 0.142981 0.122749NS NS 4.997617 NS NS NS NS1.302879 1.123694 NS 1.844127 NS NS 0.836108

NS NS 2.398609 NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NS0.484085 NS 0.392979 NS NS NS NS1.123392 0.790328 NS 1.656426 1.114289 0.680502 0.610705

NS NS NS 9.025246 NS NS NSNS NS NS 1.529225 1.094479 0.589202 0.53834NS NS NS 1.450034 1.147858 0.626993 0.546228

able shows fold-change in mean proportional representation of each EC between groups for each comparison. EC changes in a comparison (adjusted p≥0.01, ShotgunFunctionalizeR) are reported as "NS".

For EC.x in comparison A vs B, table displays (mean proportion of reads mapping to EC.x in A)/(mean proportion of reads mapping to EC.x in B)

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1.631829 NS 2.321037 NS 1.512355 NS 0.477052NS 1.973465 3.619937 NS NS NS NSNS NS NS 1.621514 1.373718 NS 0.402788NS 1.093606 1.167496 1.612898 NS NS 1.187027NS NS NS NS NS NS NSNS NS NS 1.847381 1.29876 NS 0.556669NS NS 0.787417 1.597814 1.118656 0.574575 0.513631.318536 NS NS 1.798247 1.121328 NS 0.599769

NS NS NS 1.99442 NS NS NSNS NS NS 1.1786 1.192352 NS 0.584890.848603 NS NS 1.472399 1.314262 NS 0.595233

NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS 0.791342 0.810559 1.783309 1.096862 NS 0.701355NS NS NS 1.288097 NS 0.565274 0.5524171.322755 NS 0.589604 1.613936 1.264051 0.651768 0.515618

NS NS NS 1.901363 NS NS NS0.184358 NS NS 1.949021 NS NS 0.473258

NS NS NS 1.626807 NS NS NSNS NS NS NS 1.307121 1.400929 NSNS NS NS NS NS NS NSNS 1.132284 1.202391 1.658297 1.57272 1.534979 NSNS NS NS 1.689551 1.227503 NS 0.543304NS NS NS NS NS NS NSNS NS NS NS NS NS NS1.607305 1.316958 1.88527 1.449624 NS NS 0.681149

NS NS NS 3.441843 NS NS NS0.64952 1.12666 NS 1.231124 NS 0.68506 0.6822810.63573 NS NS 1.706502 NS NS 0.743185

NS NS NS 3.615138 NS NS 0.3742890.674831 NS 1.137717 1.393983 1.185947 NS 0.65596

NS NS NS 1.343826 1.254605 NS 0.652093NS NS NS NS NS NS NSNS NS NS 2.016859 1.240747 NS NS1.169966 1.141631 1.300448 2.605332 1.379913 NS 0.538238

NS NS NS 2.829233 1.364316 NS 0.543736NS NS 0.502309 1.343258 NS 0.563145 0.527859NS NS 0.209836 NS NS NS NSNS NS NS NS NS NS NSNS NS NS 1.303394 NS NS 0.533506NS NS NS 1.899128 NS NS NS

1.13748 1.075794 1.371575 2.181525 1.596025 NS 0.5816331.164786 NS NS 1.969823 1.157725 NS 0.556971

NS NS NS NS 2.662053 NS 0.205325NS NS NS 2.563266 1.609903 NS 0.346184NS NS NS NS 1.354181 NS 0.433434

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NS NS NS NS NS NS NSNS NS NS 1.744701 1.242603 0.661271 0.5321661.124599 1.161792 1.424293 1.93542 1.184368 1.430967 1.208211

NS NS NS 1.884324 NS NS NSNS NS NS NS NS NS NS

0.87555 NS 0.794595 1.945432 1.608805 NS 0.40864NS NS NS NS NS NS NS1.275692 NS 0.789846 1.413139 1.315366 0.678824 0.5160720.907894 NS 1.113881 1.42295 1.014774 NS 0.855415

NS NS NS NS NS NS NSNS NS NS NS NS NS 0.5837890.715395 1.251786 1.487054 2.347381 1.290264 NS 0.807905

NS NS NS NS NS NS NSNS NS NS 2.919049 NS NS 0.5067990.799307 NS NS 1.395173 NS 0.635824 0.643886

NS NS NS 1.544307 1.43274 NS 0.47014NS NS NS NS NS NS NSNS NS NS NS NS 0.422095 0.489629NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 0.44849 NS 0.24598 0.373427NS NS NS 1.70044 1.378007 NS 0.405545NS NS NS NS NS NS NSNS NS NS 1.375926 NS 0.458056 0.5536830.547463 NS NS NS NS NS 0.560682

NS NS NS 1.172852 NS 0.571727 NS0.787609 0.967355 0.857077 1.158534 NS NS NS

NS NS NS NS 1.723478 NS NSNS NS NS NS NS NS NSNS NS NS 2.005776 NS NS NSNS NS NS 1.556721 1.322283 NS 0.5101980.743898 1.078535 0.979537 0.697525 NS 1.263681 NS

NS NS NS 1.318054 1.161623 NS 0.6348580.705456 1.073273 1.18177 1.401002 1.192179 NS 0.632812

NS NS NS 0.391151 1.814104 0.245618 0.1353930.623489 0.908155 0.603086 1.18631 1.057056 NS 0.768672

NS NS NS 0.416183 NS 0.246181 0.238021NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NS0.906691 1.068915 1.119186 1.177392 1.004875 1.355485 NS

NS 1.225497 NS 0.815748 1.420226 0.382129 NSNS 1.120752 1.672449 1.649908 1.186336 NS 0.565174NS NS NS NS NS NS NSNS NS NS NS NS NS NS

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NS NS NS 2.060341 NS NS NSNS NS NS NS NS NS NSNS NS NS 6.192752 2.606228 NS 0.268722NS NS NS 0.570955 0.721429 2.147771 NSNS NS NS 1.591604 NS NS 0.525173NS 1.572779 1.619482 NS NS NS NSNS NS NS NS NS NS NS2.285751 NS NS NS NS NS NS

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NS NS NS NS 3.0467 0.403918 0.132575NS NS NS NS 3.872592 NS 0.226786NS NS NS 2.207893 NS NS NSNS 0.775305 0.446202 2.029353 NS NS NSNS NS NS NS NS NS NSNS NS NS 0.604919 NS 0.209078 NSNS NS NS NS NS NS NSNS NS 0.327523 NS NS NS NSNS NS NS NS NS NS NSNS 3.82938 8.6486 1.624523 NS NS 0.454813NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 1.444097 1.288528 NS 0.541846NS NS NS NS NS NS NSNS NS NS NS 2.149858 NS 0.408438NS NS NS 4.544821 NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NS

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NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 1.739983 1.50938 NS 0.358685NS NS NS NS NS NS NSNS NS NS NS 1.7907 NS 0.352888NS NS NS NS NS NS NSNS NS NS 5.161433 NS NS NS0.786943 NS 1.12135 1.332247 0.747808 1.353112 NS0.337764 NS NS 1.757436 1.209631 0.680778 0.562798

NS NS NS 1.527844 1.229211 NS 0.609752NS NS NS 2.89892 NS NS NS0.710991 1.137945 1.284182 1.525486 1.092775 NS 0.837304

NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS 0.949372 0.668421 2.630368 1.431519 NS 0.586254NS NS NS NS NS NS NSNS 0.80154 0.77418 1.325133 1.17715 NS 0.590598NS NS NS NS NS NS 0.3740011.209072 1.066995 NS 1.495222 1.224507 NS NS

1.26631 NS 1.144053 1.721938 1.375586 NS 0.632915NS NS NS 1.736648 1.326783 NS 0.547176NS NS NS 1.847038 1.491532 NS NSNS NS NS NS 1.917667 NS 0.35440.685157 0.891408 0.581436 1.227573 0.996925 0.798039 0.80051.434595 NS NS 2.291159 1.101154 NS 0.659122

NS NS NS 0.714453 0.359176 0.399045 NSNS NS NS NS NS 0.502112 0.566058NS NS NS 1.372575 NS NS 0.565092NS NS NS NS NS NS NSNS NS NS 2.528683 1.355808 NS NSNS NS NS NS NS NS NS1.263461 1.10055 1.20259 1.592611 1.15173 NS 0.6214911.351529 1.086018 1.486944 2.577291 1.312947 2.187338 NS

NS NS NS 12.25658 1.936381 NS 0.475177NS NS NS 2.290204 NS NS NS0.813006 0.940105 0.816823 1.233589 1.057316 1.566137 NS

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NS NS NS NS NS NS NSNS NS NS NS NS NS 0.330208NS NS NS NS 1.673375 NS 0.381044NS NS NS 1.742406 NS NS NS2.179749 1.695495 2.756626 0.614059 NS 1.770127 NS

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NS NS NS 1.233258 NS 0.60709 0.5672111.082633 0.974265 NS 1.824914 0.991162 1.209886 1.220675

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NS NS NS NS NS NS NSNS NS NS NS NS NS 0.5698121.148361 NS 1.128956 1.336644 1.018866 1.037348 NS1.571055 0.831005 1.382249 2.272637 1.039395 NS NS

NS NS NS 0.761051 1.307589 0.441334 NS1.618525 0.70728 1.226666 3.9558 NS 4.010766 3.8869050.848846 0.861751 NS 1.205496 1.004529 0.639563 0.63668

NS NS NS NS NS NS NSNS NS NS NS NS NS NS1.141466 0.862364 0.760369 4.496256 1.342535 1.210327 NS0.861323 0.828694 NS 4.56664 1.245564 1.183439 NS0.822809 0.81868 0.72089 3.496729 1.350777 1.335963 NS0.822809 0.81868 0.72089 3.496729 1.350777 1.335963 NS0.649179 1.195929 0.982257 1.53591 1.292462 NS 0.556448

NS NS NS 1.387544 1.06071 0.636842 0.600392NS NS NS NS NS NS NSNS 0.791 NS 1.823047 1.333267 NS 0.471427NS NS NS NS NS NS NSNS NS NS 3.311341 NS NS NSNS NS NS NS NS NS NSNS 0.986912 0.742682 1.778316 1.331223 NS 0.757862NS NS NS NS NS NS NSNS NS NS NS NS NS NS1.486303 NS NS 1.468282 NS 0.566251 0.576938

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NS NS NS NS 1.966257 NS 0.334328NS 1.083564 1.25528 1.700787 1.008255 0.713143 0.7073051.533544 NS NS 1.180648 1.165086 0.545738 0.46841

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NS 1.000736 1.238108 1.404077 1.155666 1.073013 NSNS NS NS NS NS NS NSNS 0.816043 0.373252 1.620574 NS NS 0.659427NS NS NS NS NS NS NSNS NS NS 4.022116 1.370271 1.111777 NSNS 0.820477 NS 1.483376 1.366425 0.631652 NSNS NS NS NS 1.529923 NS 0.428059NS NS NS NS NS NS NS0.838287 0.875945 0.63177 1.384801 1.421168 NS 0.534811

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0.835518 NS NS 1.510738 1.434597 NS NSNS NS NS 1.438555 1.125027 NS 0.6994291.357924 NS 1.042608 2.247539 1.218788 1.025109 0.841089

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NS NS 1.569005 1.259114 1.141474 NS 0.619678NS NS NS 2.337622 NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS 1.189964 NS NS NS NS 0.633699

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NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 2.091532 1.373512 NS 0.64927NS NS NS NS NS NS NSNS NS NS 1.214563 NS 0.537473 0.554719NS NS NS 2.559261 NS NS NSNS NS NS 1.784301 1.249752 0.52773 0.4222680.808596 0.898104 0.854073 1.540461 1.207637 0.605943 NS0.683509 0.641324 0.467822 NS NS NS NS

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NS NS NS NS NS NS NS0.712076 0.945442 0.756183 1.212317 1.111195 NS 0.643207

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NS NS NS NS NS NS NSNS 1.098032 1.438672 1.463822 1.19585 0.655207 NSNS NS NS NS 1.252941 NS 0.504553NS NS 0.311312 NS 1.317994 0.573866 NSNS NS NS 1.211764 1.157199 1.036808 0.895964NS NS NS 0.358514 NS 0.15018 NSNS NS NS 0.612107 NS 0.308173 0.286821NS NS NS NS NS NS NS1.216922 NS NS 1.92312 1.339577 NS 0.4625031.128035 NS 1.223172 1.802498 1.17675 NS 0.6542050.889136 NS NS 1.329014 NS NS NS0.817424 NS NS 1.399179 1.064181 0.607631 NS1.078847 0.930582 0.805613 1.837607 1.153985 0.701573 NS1.264919 1.101523 1.159425 1.778579 1.017071 1.071714 NS0.785346 0.867305 0.665038 1.296643 NS NS NS

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NS NS NS 2.44571 1.166324 NS 0.794235NS NS 1.150268 1.624559 1.093915 0.669609 NSNS 0.9383 0.823701 1.579617 1.006811 0.697058 0.692342NS NS NS 1.57682 1.18944 NS 0.5409440.931366 NS 1.103272 1.405593 1.170675 0.695777 NS

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NS NS NS 1.624091 1.185671 NS 0.785126NS NS NS 1.361036 1.214517 NS 0.625924NS NS NS NS NS NS 0.507293NS NS NS 1.520456 1.302397 NS NS1.240414 NS 1.16068 2.218619 1.16462 1.049043 NS

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NS NS NS 0.667893 3.08806 1.519088 NSNS NS NS NS NS NS NSNS NS NS NS 1.304358 NS 0.383953NS NS NS 1.311263 NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 2.621094 NS NS NSNS NS NS 1.571284 NS NS 0.529728NS NS NS 1.397928 1.17935 NS 0.572649NS NS NS NS NS NS NSNS NS NS 2.263132 NS NS NSNS NS NS NS NS NS NS0.561854 1.043897 NS NS NS 0.501812 0.566229

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NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS 1.92325NS NS NS 1.835069 NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS 0.429851 NSNS 0.824481 0.806103 1.287279 1.083792 NS 0.8229372.345425 NS NS 2.312464 2.123163 NS NS

NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 1.894861 1.081562 NS 0.803516NS NS NS NS 1.378191 NS NSNS NS 2.026167 NS NS NS NSNS NS NS NS NS NS NSNS NS 2.026167 NS NS NS NS

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NS NS NS NS 1.710783 NS NSNS 1.605384 2.106703 1.434123 NS NS 0.6822250.798392 0.81279 NS 1.612795 NS 0.520241 NS

NS NS NS NS NS NS NSNS NS NS NS 1.505768 NS 0.414957NS NS NS 1.251315 NS 0.435483 0.405783NS NS NS NS 1.660251 NS NSNS NS NS NS NS 0.279044 NS0.508949 NS 0 1.599905 1.238713 NS 0.572645

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0.81383 0.968663 0.69041 1.43266 1.062382 0.695094 NSNS NS NS NS 2.007243 NS 0.348296NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NS1.248378 1.278945 1.304788 1.443297 1.346984 NS NS1.472501 1.067361 1.355636 1.353736 1.302942 NS NS0.919571 0.950796 0.798569 1.542058 1.058125 NS 0.807873

NS NS NS 1.374243 1.078325 NS 0.701789NS NS NS NS NS NS NSNS NS NS 1.758467 1.303085 0.65756 NS1.383058 NS 1.595575 1.423401 1.152625 0.582727 NS

NS NS NS 1.583767 1.089682 0.634443 NS1.172323 1.184464 1.295248 1.515757 1.148457 NS 0.709478

NS NS NS 1.479803 1.148519 NS 0.6424720.758194 NS NS 1.544834 NS 0.615847 0.6047541.178311 0.808866 NS 1.760201 1.269458 NS NS

NS NS NS 2.024788 NS NS NSNS NS NS NS 2.684761 NS NSNS 0.882276 0.8542 1.338582 1.252834 0.681115 NS0.745907 NS NS 1.372043 NS NS NS

NS NS NS 1.321763 NS 0.41164 NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 1.825467 NS NS NSNS NS NS NS 1.942258 NS 0.389476NS NS NS NS NS NS NSNS NS NS 1.535687 1.171527 0.707987 NSNS NS 0.845878 1.352653 1.141762 NS NSNS NS NS 1.668754 1.271 NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NS1.145827 NS NS 1.481525 1.208469 0.70613 NS

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NS 1.169167 1.260159 1.531665 1.161005 NS NS1.136374 1.114556 1.166838 1.69219 1.262635 0.676363 NS

NS NS 0.723328 1.418592 1.228709 NS NSNS NS NS 1.298399 NS 0.49046 NSNS 1.11722 NS 1.480176 1.128208 0.69657 NSNS NS NS 2.42446 1.502659 NS NSNS NS NS 1.226632 1.057928 0.558657 NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 2.263074 NS NS NS0.834647 0.917163 0.746618 1.625464 1.159079 0.640525 NS

NS NS NS 1.524351 1.096477 0.605443 NSNS 0.934345 NS 1.800921 1.093136 0.691594 NSNS NS NS NS NS NS NSNS NS NS NS NS 0.446808 NSNS NS NS 1.572988 NS NS 0.37497NS NS NS NS 1.415955 NS 0.4877530.599035 1.003737 0.765884 1.435734 1.173548 NS NS

NS 0.563436 NS 1.810854 NS 0.506597 0.56356NS NS NS 1.848101 1.149742 0.602475 NS0.760416 NS NS 1.562204 1.148797 0.636833 NS1.504604 1.069295 1.430004 1.622974 1.129806 NS 0.6710992.007082 NS NS 1.805111 1.281536 NS 0.528846

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NS NS NS NS NS NS NS1.215901 NS 0.753306 1.280229 1.088888 0.708166 NS0.916598 NS NS 1.600593 1.183702 NS NS

NS NS NS NS 1.338425 NS 0.357012NS NS NS 1.421857 1.076867 0.689919 NSNS 1.162869 NS NS NS 0.554053 NSNS NS NS 1.544904 NS NS NSNS 0.905816 0.81062 1.642183 1.168395 NS NS1.199308 1.143734 1.500712 1.762714 1.066085 NS 0.7696041.337362 NS NS 1.88175 0.949996 0.527385 NS0.703841 NS NS 1.570803 1.729517 NS 0.5722921.301702 NS 0.783621 1.520154 1.106663 NS NS

NS NS NS 1.812653 1.117516 NS NSNS NS NS 3.265578 NS NS NSNS NS NS 1.64376 0.836462 NS NSNS NS NS 1.654761 1.279927 0.430075 NSNS NS NS 1.727887 NS NS NSNS NS NS 1.657771 0.841512 NS NS

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NS NS NS NS NS NS NSNS NS NS NS NS NS 0.4950350.894215 NS NS 1.761069 1.207554 NS NS

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NS NS NS NS NS NS NS1.188341 1.223633 1.601422 1.47773 1.099773 0.581211 NS0.826365 0.922606 0.717199 1.513293 NS NS NS

NS NS NS 1.814385 1.217751 NS NS0.757253 0.816852 0.614111 1.575972 1.237657 NS NS0.667637 NS NS 2.052791 NS 0.46205 0.554941

NS NS NS NS NS NS 0.554197NS NS NS 0.545299 0.957063 1.93851 NS0.689834 0.841117 0.725135 1.67592 1.208691 0.69318 NS

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NS NS NS NS NS NS NSNS NS 0.383369 NS NS NS NSNS NS NS 1.508041 NS NS 0.475147NS 0.56863 NS NS NS NS NSNS 0.706942 0.62527 0.990059 1.071872 1.030186 NSNS NS NS NS NS NS NSNS 0.920785 1.051266 1.378002 1.256951 0.615872 NSNS NS NS 3.360258 NS NS NSNS NS NS NS NS 1.322174 NS0.694662 0.861575 0.736619 1.439819 1.196029 0.658521 NS

1.75983 1.043869 1.41819 3.298442 1.146589 NS 0.70556NS NS NS NS NS NS NSNS 0.807365 NS 2.059302 1.086851 NS NSNS NS NS NS NS NS NSNS 1.110301 NS 2.467238 1.176497 0.621446 NSNS NS NS NS NS NS NS

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1.096269 NS NS 3.246181 3.246873 3.245083 NSNS NS NS 2.068741 1.335636 0.512089 NSNS NS NS 1.449504 1.249421 NS NSNS 0.942386 0.721767 1.488442 1.264094 NS NSNS 0.926762 NS 1.358289 1.034384 0.531922 NSNS NS NS 1.681818 1.08379 0.57029 NS1.542677 NS NS 1.805193 1.140611 0.576812 NS0.580677 NS 0.22686 1.38817 NS NS 0.461615

NS NS NS 2.419273 1.373339 NS NS0.870672 0.815875 0.33349 0.105376 0.770681 2.07446 NS

NS NS NS NS NS NS NSNS NS NS 1.614549 NS 0.586979 NS0.844191 NS NS 1.443699 1.325926 NS NS

NS NS NS NS NS NS NSNS NS 0.54083 2.125077 1.680476 NS 0.451369NS NS NS 1.581378 1.521219 NS NSNS 1.787083 2.614104 1.707003 1.106848 0.68022 NS1.156646 1.077041 NS 1.578812 NS 2.575357 NS

NS NS NS NS NS NS NSNS NS NS 1.802388 1.218532 NS NS0.909662 NS NS 1.656662 1.257447 1.018476 0.8099550.803835 0.880632 0.467625 1.351306 1.160967 NS NS

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NS NS NS NS 2.732389 NS NSNS NS 0.34272 1.940595 1.301301 NS NS1.285084 1.013861 1.347021 1.136221 2.417985 4.620725 NS

NS 0.988474 NS 1.793537 NS NS 0.515617NS NS NS 1.650467 NS NS NSNS NS NS 1.807816 1.3625 0.476855 NSNS 0.847979 NS 1.258314 1.278537 NS NSNS 0.799923 0.804398 3.110577 1.122599 0.699248 NS0.907901 0.988146 0.855781 1.390202 1.127842 0.5931 NS

NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 1.829489 NS NS NSNS NS NS NS NS NS 0.4980931.311987 1.093682 1.335617 2.090515 NS 1.371673 1.206124

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0.835688 0.94976 0.828411 1.493831 1.178909 0.659084 NS1.574074 1.263661 NS 1.074445 0.946745 1.629012 NS0.685964 0.684716 0.453738 NS NS NS 1.2539051.382083 NS NS 1.760355 1.258498 0.588012 NS1.139513 NS 0.872631 1.553986 1.057942 0.694581 NS

NS NS NS NS NS NS NSNS NS NS 2.279517 NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS 1.211748 1.360064 1.475697 0.998104 NS NSNS NS NS 1.673192 NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS 2.651028 NS NSNS NS NS NS NS 0.435623 0.587915NS NS NS 1.355955 NS 0.480274 0.567749NS NS NS NS NS NS NSNS NS NS 4.026983 NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NS0.644196 0.889769 0.465952 1.616931 NS 0.446263 NS0.650119 0.880339 0.716388 NS 1.707845 NS NS0.830671 1.037808 0.777493 1.443475 1.033285 0.59827 NS

NS NS NS NS NS NS 0.384921.610299 1.0422 1.321685 1.902969 1.122322 NS NS

NS NS NS 1.216377 1.116577 0.608316 NSNS NS NS NS NS NS NS0.846637 NS 1.254326 2.753077 1.365203 NS NS1.216461 0.976848 1.288544 2.317031 1.15515 1.293982 1.1201850.865406 NS NS 1.696239 1.159188 NS NS0.787368 0.860421 0.645936 1.671846 1.40328 NS 0.7257681.249013 NS NS 1.676026 1.487231 0.658944 NS0.941844 NS NS 1.453806 1.039743 0.604907 NS

NS NS NS NS NS NS NSNS NS NS NS 3.306228 NS NS1.151518 0.957725 0.848267 1.884064 1.114564 0.685908 NS

NS NS NS 1.930026 1.39117 0.654274 NS0.715936 NS 1.216069 1.402689 1.219451 0.579656 NS0.920597 0.945078 0.843109 1.77365 1.197951 0.691868 NS1.125916 NS NS 1.431615 NS NS NS

NS NS NS NS NS NS NSNS NS NS NS NS 0.280803 NS1.092283 0.897768 0.672565 2.107282 1.312502 NS NS

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1.396937 0.976626 1.222556 1.577108 1.594492 NS NS1.106737 NS NS 1.2731 1.350925 NS NS0.803835 0.880632 0.467625 1.348584 1.165902 NS NS

NS 0.90987 0.696577 1.589836 1.160709 0.721162 NSNS NS NS 1.303391 1.26627 0.646413 NS1.444671 0.988047 NS 1.579707 1.114572 NS NS

NS 0.741165 0.593007 1.451183 1.373844 NS NS0.860794 0.883192 0.8093 1.399692 1.237386 NS NS

NS 0.89883 0.782061 1.88306 1.108071 0.706676 NSNS NS NS 1.184647 1.066059 0.599012 NSNS NS NS NS NS NS NS1.269951 NS NS 1.400058 NS 0.538462 NS

NS NS NS 2.145928 NS NS NSNS NS NS 1.602776 1.255579 NS NSNS NS NS NS NS NS 0.437858NS NS 4.265103 NS NS NS NS0.880298 NS NS 1.487905 1.202137 0.681123 NS

NS NS NS 1.784805 NS NS 0.7589141.542677 NS NS 1.805691 1.144429 0.579415 NS0.897859 1.06995 1.333692 1.65229 1.085458 NS NS1.295192 NS NS 1.49996 1.280845 0.619057 NS

NS NS NS 1.797334 1.267318 NS NS1.112461 NS NS 4.193096 1.467235 NS NS

NS 0.878252 0.827478 1.60814 1.109593 0.699691 NSNS NS NS NS 1.372656 NS NSNS NS NS 1.813511 1.266833 NS NSNS NS 0.789694 1.570747 1.167635 NS NS1.289476 NS NS 1.754036 1.103062 0.599023 NS

NS NS NS 1.376775 1.045117 NS NSNS NS NS NS 1.519987 0.649721 NSNS NS 2.845351 1.420959 NS NS 0.6714630.677654 NS NS 1.116172 NS NS 0.7846530.783671 1.058926 1.17762 1.220037 1.264883 1.98565 NS

NS NS NS 2.122561 1.614113 NS NSNS NS NS NS 2.278323 NS NSNS NS NS NS 1.660106 NS NSNS NS NS NS 2.191866 NS 0.303358NS NS NS 1.51705 1.391561 0.602558 NS1.401817 1.052002 1.368465 0.14224 0.69652 0.538416 NS

NS NS 1.162511 1.631284 NS 0.625594 NSNS NS NS 1.57507 NS NS NS0.694662 0.861575 0.736619 1.439819 1.196029 0.658521 NS0.652042 NS 0.691377 NS 1.208857 NS NS

NS NS NS 2.198743 1.615896 NS NS1.077669 1.004326 1.154775 1.51033 1.161906 0.757244 NS1.371612 NS NS 1.962543 1.149338 NS NS

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NS NS 0.360746 1.459289 1.235164 NS NS0.822435 NS NS 1.795786 1.103719 0.617896 NS

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NS NS NS 2.291298 NS NS NSNS NS NS 1.975643 1.21555 1.134112 NSNS NS 0.760758 1.205093 1.212739 NS NSNS NS NS NS NS NS NSNS 0.780906 0.552124 1.149178 1.13112 0.547437 NSNS NS 0.82008 1.498967 1.188974 0.656321 NSNS NS 1.557895 NS NS NS NSNS NS NS 1.451337 NS NS 0.576696NS NS NS 5.282146 NS NS NSNS NS NS NS NS NS NSNS 0.656406 0.390113 1.66224 NS NS 0.486214NS NS NS 2.010435 NS NS NSNS NS NS 1.830171 NS NS NSNS NS 0.522937 1.768347 1.529363 NS NSNS NS NS NS NS NS NSNS NS NS 1.746962 NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 1.273631 NS NS NSNS NS NS 3.873462 1.487986 NS NSNS NS NS 0.181431 1.578969 0.074495 NSNS NS NS NS NS NS NS1.374532 NS 0.504006 1.161787 1.133356 0.495968 NS

NS NS NS NS NS NS NS1.136577 NS NS 1.396127 1.25249 0.558303 NS1.048748 NS NS 1.522809 1.178341 0.767839 NS1.400311 NS NS 1.559305 1.078872 0.62122 NS0.605057 0.984463 0.563177 1.88468 NS NS NS1.987354 1.344423 1.540866 2.357294 1.26993 0.59644 NS

NS NS NS 1.605195 NS NS 0.534618

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NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 1.776769 NS NS NSNS NS NS 1.510944 1.265601 0.660866 NSNS NS NS 1.382904 NS NS NS0.710781 1.129963 1.135081 1.116947 NS 0.677053 NS

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NS 0.938494 0.790521 1.554778 1.201215 0.60953 NSNS NS 1.225449 2.054485 NS 0.580758 NSNS NS NS 1.37592 1.28921 0.742711 NSNS NS NS NS NS NS NS1.373665 1.117321 1.214196 NS NS NS NS

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0.885021 NS 0.782857 1.401158 1.110411 0.628529 NS0.909069 NS NS 1.081033 1.072557 0.953166 NS

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NS NS NS 1.817693 1.220682 0.605446 NSNS 0.877748 0.716813 1.417523 1.069419 0.687662 NS0.911921 0.907341 0.832683 1.290156 1.080794 0.561514 NS

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NS 1.086056 NS 1.438164 1.203941 0.699377 NSNS NS NS 1.341025 NS NS NSNS NS NS NS NS NS NSNS 10.69594 17.75073 NS NS NS NSNS NS NS 1.599223 1.514924 NS NS

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NS NS NS NS NS NS NSNS NS NS NS NS 0.257948 NSNS NS NS 2.640332 NS NS NSNS NS NS NS 1.6321 NS NSNS NS NS 1.174008 NS NS NSNS NS NS 2.078585 NS NS NSNS NS NS NS NS NS NSNS NS NS 3.636561 NS NS NSNS NS NS NS NS NS NSNS NS 1.411163 1.267146 NS 1.096491 1.193923NS NS NS NS NS NS 0.563129NS NS NS NS NS NS NSNS NS NS 1.292012 1.270623 NS NSNS NS NS 1.530245 1.257781 0.560315 NSNS NS NS NS 1.358902 0.616941 NS0.409836 NS NS 2.453297 NS NS NS

NS 1.129404 1.41121 1.572528 1.025187 NS NSNS NS NS NS NS NS NSNS 0.595755 0.493419 1.912851 NS 0.583881 0.697765NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 1.647905 NS NS NS1.677318 NS NS 1.213146 1.172186 NS NS0.761045 NS NS 1.497083 1.427667 NS NS

NS NS NS 1.977239 1.362307 NS NSNS NS NS NS NS NS NSNS NS NS 1.423259 1.149158 0.617684 NSNS NS NS 1.444159 1.125201 NS NSNS NS NS 1.29823 1.351737 0.585871 NSNS NS NS NS NS NS NS0.690763 NS NS 1.78592 NS NS NS0.743858 NS NS 1.288612 1.245315 0.593849 NS0.162935 0.354224 NS NS NS NS NS0.550281 0.836134 0.571229 1.424849 1.127756 0.595742 NS0.819702 NS NS 1.476565 1.27997 0.623664 NS

NS NS 0.289627 2.316159 1.343476 NS NSNS NS NS NS NS NS NSNS NS NS NS 2.119493 NS NSNS NS NS NS NS NS NSNS NS NS 1.44075 1.103469 0.600604 NS1.059645 1.096229 1.112526 1.560699 1.074999 0.624326 NS

NS 1.09134 1.374214 1.7246 1.290561 1.0878 NS1.665475 NS 1.517259 1.688724 1.119258 0.569751 NS1.339062 1.37154 NS 1.952219 1.361287 NS NS

NS NS NS 2.286976 3.687308 NS NSNS NS NS NS NS NS NS

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NS NS NS NS NS NS NSNS NS NS 2.594924 1.495532 0.582837 NS

0 NS NS NS 1.661253 NS NSNS NS NS NS NS NS NSNS NS 1.221196 1.719136 1.116971 NS NSNS NS NS 3.764955 NS NS NSNS NS NS 1.29329 1.015826 0.537568 NSNS NS NS 1.474604 1.660334 NS NSNS NS NS 4.437828 NS NS NSNS NS NS 2.449557 1.833038 NS NSNS NS NS 1.610878 1.650681 0.650293 NSNS 0.824726 0.705259 1.144293 1.071314 0.625605 NS1.080886 1.03483 NS 1.491548 1.303635 0.599253 NS

NS NS 0.909925 1.600122 1.094173 0.640445 NSNS 0.937568 NS 1.576994 1.115063 0.672338 NSNS NS 0.865884 1.661319 1.130053 0.607011 NSNS NS NS 1.631349 1.175554 0.646236 NSNS NS NS 1.750833 1.099418 0.616388 NS

0.91559 NS 0.854594 1.826567 1.022124 0.604114 NSNS NS NS 1.42371 NS NS NSNS NS NS 1.519337 NS 0.518237 NS1.476876 NS 1.432379 1.458593 1.148607 NS NS

NS NS NS 1.514014 NS NS NSNS 0.820143 0.689119 2.198699 1.127855 0.593048 NS1.117508 NS NS 1.947762 1.289235 0.645851 NS

NS 0.785033 0.769359 NS 1.679108 NS NS1.102334 0.947 0.75025 2.344739 1.197387 NS NS1.195123 0.960266 NS 1.533233 1.116041 0.617194 NS

NS NS 1.456754 2.033653 1.155755 NS NSNS NS NS 1.624621 1.233311 0.569299 NSNS NS NS NS NS 2.679499 NSNS NS NS 1.283148 1.314553 0.53522 NSNS NS NS 1.289712 1.110151 0.573356 NSNS 0.892218 0.831319 1.412125 1.132763 0.596197 NSNS NS 1.616818 1.512001 NS 0.458442 NS1.165004 NS NS 2.380805 1.272903 0.652758 NS

NS NS NS NS NS NS NSNS NS NS NS NS NS NS

1.26924 2.579344 6.733416 1.668754 2.360612 NS NS1.711298 NS NS 1.983755 1.250063 0.593517 NS

NS NS NS NS NS NS NSNS 6.437645 NS NS NS NS NS0.713685 NS NS 0.545682 NS 0.374095 NS

NS NS NS NS NS NS NS1.388912 0.888662 1.07096 1.628146 NS NS NS1.236417 1.171782 1.360676 1.85166 1.238272 0.541678 NS

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NS NS NS 1.892056 NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS 0.217436 NSNS NS NS 2.800307 1.484303 NS NS0.614002 0.77379 0.364964 1.281134 1.224393 NS NS1.665015 1.339256 2.070348 0.571169 3.154158 1.516494 NS

NS NS NS 2.082261 NS NS NSNS NS NS NS NS 0.464807 NSNS NS NS 1.759287 1.105574 NS NS1.233972 NS 0.8818 1.791956 1.202028 NS NS

NS NS NS 1.36409 1.075002 0.623296 NS0.712644 0.674523 0.560531 NS NS NS NS

NS 0.874 0.537497 1.449963 1.237152 0.671894 NS0.491276 0.850538 NS 1.374406 1.319479 NS NS

NS NS NS 1.275313 1.253077 0.643833 NSNS 1.101722 1.201426 1.401815 1.338328 NS NSNS NS NS NS NS NS NSNS NS NS 2.845909 NS NS NSNS NS NS 1.764452 0.988614 NS NSNS NS NS NS NS NS NSNS NS NS 1.299625 1.461544 NS NSNS NS NS NS NS NS NSNS NS NS NS 1.834052 NS NS1.075499 NS NS 1.38416 1.043499 0.687009 NS

NS 0.862701 0.513553 1.813428 1.177278 0.691572 NS1.631857 NS NS NS NS NS NS

NS NS NS 4.287425 NS NS NSNS NS NS NS NS NS NS1.479702 1.070214 1.175038 2.37909 1.183401 0.74966 NS

NS 0.787937 0.29986 NS NS 0.408661 NSNS NS NS 1.260977 1.105962 0.577979 NSNS NS NS 1.886053 1.377657 NS NSNS NS NS NS NS NS NS0.871823 0.907642 0.857542 1.573021 NS NS NS0.827364 NS 0.631271 4.802789 2.040563 NS NS

NS NS NS NS NS NS NS0.917346 NS 0.812683 1.74669 1.222536 NS NS

NS NS NS 1.233608 1.150486 0.55589 NSNS NS NS 1.819544 NS NS NSNS NS NS 1.467464 1.115465 NS NS

0.88179 0.99824 NS 1.639333 1.230114 1.057896 NSNS 1.089842 0.933973 1.848699 1.238399 0.669058 NSNS NS NS 3.467488 NS NS NSNS NS NS 3.399705 NS NS NSNS NS NS 3.800534 NS NS NSNS NS NS 3.830594 NS NS NS

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NS NS NS 2.720033 NS NS NS0.779226 NS NS 1.247717 NS 1.973067 NS1.078915 0.916301 0.872306 1.462094 NS 0.597945 NS

NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS 1.189456 1.487764 NS NS NSNS NS NS NS 2.056233 NS NSNS NS NS 2.714689 NS NS NS0.591858 NS NS NS 1.400032 NS NS

NS 0.801629 0.752502 1.199328 1.024917 0.524945 NSNS NS NS NS NS NS NSNS NS NS NS NS NS NS

0 0.263472 NS NS 1.252123 NS NSNS NS NS NS NS NS NSNS NS NS 1.905238 1.229133 NS NSNS NS NS NS NS NS NSNS NS NS 1.986944 NS NS NSNS NS NS 8.072936 NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NS0.707983 NS 0.443271 1.738879 NS NS NS

NS NS 0.798757 1.495685 1.191429 NS NSNS NS 2.3312 NS NS NS NSNS NS NS NS NS NS NSNS NS NS 1.535318 NS 0.492206 NSNS NS 0.578654 NS NS NS NSNS NS NS NS NS NS NS0.866762 1.162983 1.13923 1.521647 1.054571 NS NS

NS NS NS NS NS NS NS1.131027 NS NS 1.697671 1.126682 NS NS

NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS 0.445752 NS 1.482211 NS NS NSNS NS NS 1.772669 1.21041 NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 2.150926 1.067301 0.641105 NSNS NS NS NS NS NS NSNS NS 2.368054 NS NS NS NSNS NS NS 3.128353 2.692426 1.577799 NSNS NS NS 2.281297 NS NS NSNS NS NS NS NS NS NS

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NS NS NS NS NS NS NS0.742997 NS NS 1.259571 1.202559 NS NS1.188154 0.885866 0.77865 1.711615 1.19388 0.680766 NS

NS NS NS NS NS NS NS1.249409 1.11167 NS 1.499762 1.108429 NS NS

NS 0.35996 0.406626 1.369265 NS 0.435423 NSNS NS NS 1.185248 1.187199 NS NSNS NS NS NS NS NS NSNS NS NS NS 1.345411 NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 3.133179 NS NS NSNS NS NS NS NS NS NS1.150646 NS NS 1.399898 NS NS NS

NS NS NS NS NS NS NSNS NS NS 1.51658 NS NS NSNS NS NS NS NS NS NS0.758635 0.888393 0.584967 NS NS NS NS1.519559 NS 1.247264 2.40812 1.222639 NS NS

NS NS NS NS NS NS NSNS 0.915911 NS 1.635821 1.189671 0.720829 NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 1.442222 1.109139 0.508789 NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NS1.101117 1.015077 NS 1.603747 1.062207 0.683968 NS

NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 3.474312 NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS 0.385914 NS 2.474511 NS NS NSNS NS NS 4.145334 1.38704 NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS 3.268498 NS NSNS NS NS 1.271398 1.206502 NS NSNS 0.831336 0.737023 1.663192 1.128653 0.713999 NS

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NS NS NS NS NS NS NSNS NS NS 4.312564 NS NS NSNS NS 1.208168 1.390221 1.371654 NS NSNS NS NS NS NS NS NSNS NS NS 1.029468 0.402871 1.292774 NSNS NS NS NS NS NS NSNS 0.590337 0.312285 1.731413 NS NS NSNS NS NS 1.324452 NS 0.451691 NSNS NS NS 1.43472 NS 0.609959 NSNS NS NS NS 1.804453 NS NSNS NS NS NS NS NS NSNS NS NS 2.226521 NS NS NSNS NS NS 2.254173 NS 0.545942 NSNS NS NS 1.591591 1.128128 NS NS0.691599 0.870452 0.748486 3.113324 1.23582 NS NS

NS 0.975415 0.908159 1.656305 1.063249 0.717317 NS0.783148 0.898974 0.816815 1.217952 NS NS NS1.464537 1.26592 1.301841 1.582689 1.383295 NS NS

NS NS NS NS NS NS NS0.809171 NS NS 1.313867 1.08793 NS NS

NS NS NS NS NS NS NSNS NS NS 1.142773 1.371248 NS NS0.837966 NS 2.099451 1.397056 1.156567 NS NS2.098784 NS NS NS 1.180087 NS NS1.407857 0.863772 NS NS 1.163321 NS NS

NS NS NS 3.039233 1.751524 NS NS0.71917 1.114291 1.173573 1.524425 1.046244 0.72043 NS

NS NS NS 1.710749 1.021759 0.609714 NSNS NS NS NS NS NS NSNS 0.884714 0.655533 1.647381 1.138228 0.759844 NSNS NS NS 1.659201 1.192094 NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 5.087975 2.217966 NS NSNS NS 0.716851 1.989456 1.762156 0.411089 NSNS NS NS NS NS NS NSNS NS NS NS 1.546446 NS NSNS NS NS 1.605326 1.578572 NS NSNS NS NS 1.920592 1.316647 NS NS

0.75536 NS NS 1.627083 1.111683 0.549202 NSNS NS NS 1.496013 NS NS NSNS NS NS NS NS NS NSNS NS NS NS 2.046779 NS NSNS NS NS 3.724817 1.82407 NS NSNS NS NS 2.371757 NS 1.966447 NSNS NS NS NS NS NS NS

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NS NS NS 1.619375 NS NS NSNS NS NS 1.398704 1.048185 0.718517 NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 1.436987 NS 0.592627 NSNS NS NS 1.375075 1.297344 NS NSNS NS NS NS 1.319906 1.271006 NSNS NS NS NS NS NS NS1.363474 NS NS NS 1.126465 NS NS

NS NS NS 0.349579 0.489841 NS NSNS NS NS NS 1.744775 NS NSNS NS NS 1.960642 1.592544 0.297324 NS0.823326 0.874756 0.667592 1.575788 NS NS NS

NS NS NS NS 1.62 NS NS0.839127 1.302035 1.411473 NS 1.288862 NS NS

NS NS NS 1.265832 1.259002 0.601679 NSNS NS 1.250087 1.401018 1.212598 NS NSNS NS NS 2.407101 NS NS NSNS NS NS 1.445841 NS NS NSNS NS NS 1.499458 1.919637 NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS 1.199154 NS NS NS NSNS NS NS 2.358349 NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NS0.645553 0.555003 0.202334 1.699797 1.466548 NS NS

NS NS NS NS 1.422503 NS NS1.301602 NS 1.147935 1.979009 1.069305 NS NS

NS 0.897387 0.837769 1.335982 1.182219 0.678355 NS0.721905 0.863396 0.648223 2.295866 NS NS NS1.460003 1.168847 1.586017 1.508348 1.112891 NS NS1.192534 1.188822 NS 1.516794 1.073025 0.657588 NS

NS NS 1.271783 1.605448 1.168249 0.685269 NSNS 0.979305 NS 1.718808 NS NS NS1.251792 1.160373 1.434657 1.92805 NS NS NS

NS NS NS NS NS NS NSNS NS NS 2.094863 NS NS NSNS NS NS NS NS NS NSNS 0.807467 NS 0.974054 NS 0.691641 NSNS NS 0.587503 1.405879 1.358037 NS NS

0.86145 0.886957 0.77357 1.55035 1.036022 NS NSNS NS NS 1.378033 NS NS NS1.130051 NS 1.1266 1.386108 1.020288 1.10605 NS

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NS NS NS 2.206113 1.813963 NS NSNS NS NS NS NS NS NS1.588059 1.864273 2.029663 NS NS NS NS

NS NS NS NS NS NS NSNS NS NS NS NS NS NS1.048666 0.965052 1.026751 1.771662 1.09377 0.756351 NS

NS NS NS NS NS NS NSNS NS NS 2.003213 1.143541 0.678348 NSNS NS NS 1.060967 0.966817 2.073869 NS0.828971 NS 0.786854 0.601871 1.038149 2.439098 NS0.566882 NS NS 1.529805 1.293403 NS NS

NS NS NS 1.501034 1.297103 0.653392 NSNS NS 1.357183 1.365051 1.295511 0.679593 NS

3.51719 2.363891 NS NS NS NS NSNS NS NS NS NS NS NS0.772924 NS NS 1.343127 1.19506 NS NS

NS NS 0.545411 1.614076 1.159114 0.608823 NS0.806845 NS 0.763601 1.269822 1.167074 0.596069 NS

NS NS NS NS NS NS NSNS NS 0.880278 2.050203 1.282244 0.657021 NSNS NS NS NS 2.273208 NS NS1.198828 1.19361 NS 1.438613 1.088088 0.64899 NS

NS NS NS NS 2.285612 NS NSNS NS NS 1.600938 NS NS NSNS NS NS 1.386575 0.385067 1.043233 NSNS NS NS NS NS NS NS2.181647 NS NS NS NS NS NS

NS NS NS NS NS NS NS3.51719 2.363891 NS NS NS NS NS

NS NS NS NS 3.004779 NS NSNS NS 0.65931 1.790658 1.362791 NS NSNS NS NS NS NS NS NS

0.89131 NS NS 1.593879 1.218789 0.717933 NSNS NS NS 1.179942 1.093749 NS NS0.670758 1.061785 0.727136 1.194453 1.123199 0.593921 NS0.910842 1.027678 1.018472 1.697997 1.112447 0.748256 NS

NS NS NS 1.520116 1.272856 0.585107 NS1.370925 0.968505 0.852576 2.19655 1.094144 NS NS

NS NS NS NS 3.868354 NS NSNS 0.576672 NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 1.512957 1.141387 0.644259 NSNS NS NS NS NS NS NSNS NS NS 1.477111 1.058979 0.686302 NS0.312913 1.131444 1.173989 1.232069 1.328623 0.514886 NS

0.72967 0.874107 0.88759 1.268599 NS NS NS

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NS NS NS 1.759686 1.19743 0.617464 NSNS NS NS 1.486412 NS NS NSNS NS NS 1.218546 1.263129 NS NS0.446647 NS NS 1.40617 1.346841 NS NS

NS NS NS NS NS NS NS1.395436 NS NS 1.276902 1.233342 0.632031 NS

NS NS NS 1.504584 1.203449 0.690748 NSNS NS NS NS NS NS NS0.735107 0.887224 0.905124 1.560321 NS NS NS

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NS NS NS 0.584756 0.758737 1.71053 NSNS NS NS 1.474458 NS 0.535298 NSNS 1.151459 1.232593 1.319075 NS NS NSNS 0.790364 0.692827 2.54856 NS NS NSNS NS NS 1.438608 1.180088 0.69028 NSNS NS NS NS NS NS NSNS NS NS 1.978082 NS NS NS1.136066 NS NS 1.826394 1.333915 0.700674 NS

NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS 1.038049 NS 1.637969 1.216921 0.773345 NSNS 0.469634 0.240619 1.476808 1.746359 NS NS

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NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 1.491944 NS 0.576118 NSNS NS NS 1.392063 1.334174 NS NSNS NS NS NS NS NS NS1.177265 0.882441 0.869474 1.451819 1.232251 1.005845 NS0.782191 NS NS 1.480161 1.076172 0.668483 NS

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NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 1.384346 1.071916 NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 1.865233 1.189833 NS NSNS 6.832391 21.54615 NS 2.612735 NS NSNS NS NS 2.780079 1.535471 NS NSNS NS NS NS NS NS NSNS NS NS 2.05243 NS NS NS1.080719 1.007809 1.289216 1.836498 1.090152 1.28227 NS1.200082 1.072405 NS 1.851793 1.118829 NS NS1.164217 NS 1.205149 1.53127 1.355037 NS NS

NS NS NS 1.920171 1.37122 NS NSNS NS NS 1.618422 NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NS0.735447 NS NS 1.377757 1.269585 NS NS

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NS NS NS NS NS NS NS1.322986 1.106641 1.34469 1.592191 1.122619 0.667739 NS

NS NS NS 2.308482 1.368086 NS NS1.200082 1.072405 NS 1.851793 1.118829 NS NS

NS NS NS NS NS NS NS0.702657 NS NS 1.51658 1.040018 NS NS

1.07737 0.952943 1.057485 1.296105 NS 0.696715 NSNS NS NS NS NS NS NS

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NS NS NS NS NS NS NS1.24049 NS NS 1.269882 1.222292 NS NS

NS NS NS 1.328576 1.152835 NS NSNS 0.564396 0.251136 2.279705 NS NS NSNS NS NS NS 1.901101 NS NSNS NS NS NS NS NS NS0.190073 NS NS 1.371558 NS 0.536274 NS

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NS NS NS NS NS NS NSNS NS NS 1.750628 NS NS NSNS NS NS 1.302305 1.314451 NS NS0.950406 0.844326 0.823709 1.485866 1.106365 0.68137 NS0.778027 NS NS NS 0.849677 0.49967 NS

NS 0.954348 0.595138 1.431559 1.062312 0.66858 NSNS NS NS NS NS NS NSNS NS NS NS NS NS NS0.726208 1.062798 1.282668 1.133006 NS NS NS

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NS NS NS 1.950898 NS NS NSNS NS 2.385966 1.230577 1.588769 0.671122 NSNS NS NS 2.926991 1.481456 NS NS0.701573 NS 0.887431 1.399981 1.088221 NS NS1.336414 NS 1.734953 4.037694 1.261095 1.604246 NS

NS NS NS 1.512663 NS 0.494812 NSNS NS NS 1.703142 1.178948 0.702525 NSNS NS NS 1.703142 1.178948 0.702525 NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NS1.167782 1.535246 1.80872 1.878862 1.38141 1.175247 NS

NS 0.800219 0.486875 NS NS NS NS1.108331 NS NS 1.468866 NS 0.645275 NS

1.36095 1.327515 1.334199 1.588154 1.149665 NS NS0.711518 0.892458 0.701271 1.282036 NS NS NS

NS NS NS 1.477812 NS 0.570306 NS1.105471 1.198997 1.180522 1.542868 1.269735 0.678631 NS

NS 1.855209 2.92128 4.589632 1.49496 1.83654 NS

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NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 2.705515 1.154436 NS NSNS NS NS NS NS NS NS1.363372 1.14968 1.349708 1.329139 1.051059 NS NS

NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS 1.134838 2.321674 1.226571 NS NSNS NS NS NS NS NS NSNS 1.082944 NS 1.982004 1.248773 NS NS1.564599 NS 1.634432 NS NS NS NS

NS NS NS NS NS NS NSNS NS NS 1.349296 NS 0.496096 NSNS NS NS NS NS NS NSNS NS NS 1.693449 NS NS NS2.267566 1.08244 NS 1.745041 1.17168 0.587944 NS

NS NS NS 1.578518 1.353326 NS NSNS NS NS 1.578518 1.353326 NS NSNS NS NS 1.641248 NS NS NSNS NS NS 2.570613 NS NS NSNS NS NS 5.514577 NS NS NS1.241008 1.097802 NS 2.022466 1.273591 NS NS0.835228 NS 1.499664 1.303118 1.201387 0.689496 NS1.162575 1.107769 1.194415 1.512791 1.110464 0.628666 NS

NS 0.935179 NS 1.368812 1.003157 0.541009 NS0.863508 1.052329 NS 1.369656 1.043908 NS NS

NS NS NS NS NS 0.298969 NS1.192278 1.043883 1.164453 1.406687 1.142942 0.612362 NS

NS NS NS NS NS NS NSNS NS NS 0.390165 0.61671 0.226409 NSNS 0.918724 NS 1.359946 1.051727 NS NSNS 0.762737 0.458588 2.137721 NS NS NS0.690535 NS 1.813309 2.041846 1.689646 NS NS

NS NS 0.811948 1.596872 1.178838 NS NS0.315145 0.543764 0.192147 NS NS NS NS

NS NS NS 1.35318 1.31999 0.621748 NSNS NS NS NS NS NS NS0.769649 0.877962 0.790647 1.69133 1.180079 NS NS

0.90614 0.816423 0.843349 1.434731 NS NS NSNS NS NS 1.56241 NS NS NSNS NS NS 1.482852 1.302157 0.630817 NSNS NS 1.371461 1.547761 NS NS NSNS NS NS NS NS NS NS1.525907 NS NS 1.595575 1.58149 NS NS

NS NS NS NS NS NS NSNS NS NS NS NS NS NS

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NS NS NS 1.547943 1.100352 0.70011 NSNS NS NS NS NS NS NSNS NS NS 1.217503 1.297747 0.580543 NSNS NS NS 1.635107 1.476263 NS NSNS 0.905031 NS 1.291871 1.212764 NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NS0.735846 0.940699 0.613498 1.24596 1.139593 NS NS

NS NS 0.792984 1.30209 1.107904 0.609464 NSNS NS 5.273517 NS NS NS NSNS NS NS 1.410452 NS NS NSNS NS NS 1.432916 1.233812 NS NS1.182777 NS 1.234509 2.232116 1.16108 0.552159 NS1.533544 NS NS 1.180648 1.165086 0.545738 NS1.234053 NS NS 1.806647 1.276557 0.720936 NS

NS NS NS NS NS NS NS0.856883 NS 0.795355 1.54887 1.220291 NS NS

NS NS NS 1.54106 1.533074 NS NSNS NS NS 1.578534 1.038647 0.662534 NS1.108571 0.985062 NS 8.335216 NS NS NS

NS 0.853981 0.813217 1.682978 1.223076 0.65848 NSNS NS NS NS NS NS NSNS NS NS 2.253397 1.28774 NS NS1.125569 0.914486 0.855704 1.307587 1.098331 0.649502 NS

0.77635 NS 0.717722 1.492261 1.074789 NS NSNS NS NS 3.355101 NS NS NS1.118428 0.917611 NS 1.552243 1.284682 0.720732 NS1.132354 1.20153 NS 1.384341 1.0393 NS NS

NS NS NS NS NS NS NSNS NS NS NS NS NS NS0.932521 NS NS 1.562253 1.075424 NS NS

NS NS NS NS 2.708049 NS NSNS NS NS 2.393483 NS NS NSNS NS NS NS NS NS NSNS NS NS 1.696899 1.116265 1.083817 NS1.450931 NS 1.381878 2.420309 1.246576 NS NS1.109295 NS NS 1.168973 1.104735 0.547423 NS

NS 0.59765 NS 1.658162 NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS 0.395945 NSNS NS NS NS NS NS NS1.156929 1.095333 1.200366 1.714472 1.186669 NS NS1.305825 1.088879 NS 1.353235 1.684009 NS NS1.346804 1.009467 1.171028 1.921099 1.175458 1.078711 NS

NS 1.207113 1.566549 2.268809 1.213143 NS NS

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NS NS 0.710713 1.272 1.212237 NS NS1.716319 1.268908 2.516433 2.569169 1.266648 NS NS

NS NS NS 1.457816 1.13065 0.587238 NS1.309993 1.085571 1.335908 1.940051 1.181251 NS NS0.344993 NS NS NS NS NS NS0.467493 NS NS 1.531313 1.725268 NS NS0.757099 NS NS 1.41548 NS 0.615747 NS1.336744 1.045295 1.406832 1.792346 NS NS NS

NS NS NS 2.395259 1.429293 NS NSNS 3.352069 NS 1.373872 1.314711 NS NS1.685661 1.10204 1.399544 3.62259 1.218392 NS NS1.779714 1.332491 1.921894 3.684588 1.962875 NS NS1.170839 1.004568 1.169376 1.547786 1.147797 1.266035 NS1.116871 1.079366 1.125192 1.41439 1.245553 0.696231 NS1.163564 NS 1.1644 1.891768 1.180787 NS NS

NS NS NS 1.342334 NS 0.58864 NSNS NS NS 1.594431 NS NS NSNS NS NS 1.829889 NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 1.966166 1.41593 NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 1.105475 NS NS NSNS NS NS NS 1.657315 NS NSNS NS NS 0.506579 0.650529 0.570773 NSNS NS NS NS NS NS NSNS NS 0.675265 1.296151 NS NS NS

0.93385 NS NS 1.899527 1.018705 0.720819 NS1.211858 NS 0.401467 1.57472 1.155647 NS NS

0.43797 0.553657 0.459052 1.630305 0.648757 1.183432 NSNS NS NS NS NS NS NS0.648478 0.897751 0.727905 1.555572 1.012953 0.690521 NS

NS NS 0.723667 1.527372 1.282049 NS NS1.105956 1.047893 1.16719 2.039482 NS 1.169309 NS

NS 1.885258 3.078772 1.134221 NS 1.34392 NS0.722776 1.28588 1.198258 NS NS NS NS

NS NS NS NS NS NS NS2.119652 NS NS NS NS 0.496899 NS1.620312 1.131445 1.654227 1.388437 NS NS NS

NS NS NS 2.377712 NS NS NSNS NS NS NS NS NS NS0.945824 0.964236 0.809048 1.634624 1.113935 0.698268 NS

NS NS NS NS NS NS NSNS NS NS 1.511296 NS NS NSNS NS NS 1.682968 0.377405 2.163818 NS

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1.184051 NS NS 1.4286 1.153032 NS NS1.074192 1.03918 1.165012 1.690933 NS 1.060282 NS

NS NS 1.286848 1.366286 1.084449 0.61268 NSNS NS NS NS 4.145613 NS NSNS NS NS NS NS NS NSNS 0.826099 0.719015 1.690393 NS 1.12868 NSNS NS NS NS NS NS NS1.406078 NS 1.155144 2.995322 1.712607 1.163986 NS

NS NS NS NS NS NS NS1.142133 NS NS 1.338777 1.049016 0.699492 NS1.105917 NS NS 1.374686 1.147297 0.571656 NS

NS 0.949411 NS 1.613363 1.084274 NS NSNS NS NS NS 1.38494 NS NSNS NS NS NS NS NS NS1.238681 NS 1.140561 2.175093 1.312721 NS NS

NS NS NS 1.864608 1.187536 0.677311 NSNS NS 1.281503 1.702901 1.049588 NS NS1.114027 NS NS 1.29798 1.000575 0.727681 NS

NS NS 1.403069 1.497098 1.391231 NS NS1.169959 NS NS 1.478385 1.072426 1.602335 NS1.095213 0.910621 0.824016 1.65538 1.129594 NS NS1.174338 NS NS 1.465083 1.096896 0.689112 NS1.145209 NS NS 1.554511 1.081621 0.709423 NS

NS NS NS 1.983017 1.14267 NS NS1.248548 NS NS 1.656477 NS 0.700483 NS

NS NS NS 1.491446 1.190094 0.709027 NS1.329073 NS 1.167034 1.56237 1.154859 0.741388 NS

NS NS NS 1.909257 NS NS NS1.092734 NS 1.181937 1.718111 1.07199 NS NS

NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS 1.558441 NS1.253868 1.086028 1.111711 1.706524 1.357038 NS NS1.348246 1.106409 1.359266 NS NS 0.641397 NS

NS NS NS 1.929296 1.256228 0.691299 NSNS NS 1.246734 1.331685 1.093663 NS NS1.243711 NS 1.172131 1.410589 1.0384 0.710003 NS1.233586 1.105837 1.209139 1.640939 1.109508 NS NS1.276231 NS NS 1.787024 NS 0.604883 NS

NS 1.075626 1.223695 1.68818 1.416234 NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS 1.132786 NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS NS NS NS NS

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NS NS NS NS NS 0.36128 NSNS NS NS NS 1.459061 0.514355 NSNS 0.941502 NS 1.5417 1.226197 NS NSNS NS NS 0.939453 NS 1.401092 NS1.726265 2.623494 3.130566 2.357906 NS NS NS

0.64701 NS 1.224895 NS 1.191877 0.683844 NSNS NS NS NS NS NS NS0.782509 NS 0.669589 1.918656 NS 0.632349 NS1.310468 1.253513 1.57341 1.558475 1.20785 NS NS

NS NS NS 1.510609 1.225712 0.49539 NSNS NS NS NS NS NS NS0.799301 0.882663 0.503193 1.668664 1.169217 0.675047 NS

NS NS NS 2.019219 NS NS NSNS NS NS 2.54641 1.820433 NS NSNS 0.513107 0.667215 1.603497 NS NS NS1.213612 NS 0.736262 2.095191 1.177136 NS NS

NS NS 0.879461 1.731418 1.079161 NS NSNS NS NS 2.1698 1.204659 0.671591 NSNS 0.919864 NS 1.687545 1.176236 NS NSNS NS NS 1.489478 1.246636 0.752098 NSNS NS NS 1.263 1.050903 NS NSNS NS NS NS NS NS NSNS NS NS 1.566948 NS NS NSNS NS NS 1.455429 1.012916 NS NSNS NS NS 1.486514 NS 0.580038 NS

1.2813 1.021035 NS 2.31245 2.851512 0.750108 NSNS NS NS NS NS NS NSNS NS NS 1.856954 0.99866 NS NSNS 0.878301 NS 2.001071 1.001715 0.528245 NS1.138499 0.852477 0.830812 1.715695 1.074811 0.658014 NS

NS NS NS 1.414927 1.107058 0.625133 NS1.565484 NS NS 1.193385 1.164779 NS NS

NS NS NS 1.349288 1.129236 0.587457 NSNS NS NS 3.319266 NS NS NSNS NS NS 3.319266 NS NS NS1.419828 NS NS 1.811057 1.026694 0.637862 NS0.770045 1.149761 1.371548 1.240866 NS 0.593173 NS

NS 1.224477 NS 1.315123 1.015858 0.636854 NSNS NS NS 1.556444 NS NS NSNS NS NS 1.623428 1.104258 NS NS1.619556 0.906314 1.350923 2.073844 1.180849 1.129938 NS1.182142 1.117796 NS 1.938519 1.135772 NS NS1.370644 1.083576 1.275887 1.695035 1.195734 0.702924 NS

NS NS NS NS NS NS NSNS NS NS 3.319266 NS NS NSNS NS NS 1.682766 1.250451 NS NS

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NS 0.801231 0.564919 1.403777 1.130673 0.614435 NS1.052482 1.04248 0.904559 1.705579 1.120383 1.032661 NS1.165924 NS NS 1.617564 NS 0.697999 NS1.309164 1.185213 NS 1.259452 1.098039 0.663735 NS1.291122 1.045213 NS 1.538196 1.177406 NS NS

NS NS NS 1.372408 1.252069 0.641881 NSNS NS NS 1.379251 1.249038 0.643645 NS0.782509 NS 0.669589 1.918656 NS 0.632349 NS

NS NS NS NS NS NS NS1.399583 1.031804 1.279141 1.445064 1.167061 0.579077 NS

NS NS 1.270067 1.572427 1.077009 0.594321 NS1.154813 0.977905 NS 2.111866 1.035349 NS NS0.699875 0.9558 0.553957 NS NS NS NS

NS NS NS NS NS NS NSNS NS NS NS NS NS NSNS NS NS 1.440805 1.310531 0.599139 NS0.635783 1.411366 1.421304 1.65533 1.12127 NS NS

NS NS NS NS NS NS NSNS NS NS 1.522916 1.337061 NS NSNS NS NS 1.235894 1.122742 0.543096 NS

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KEGG pathway KEGG categoryAmino sugar and nucleotide sugar metabolism|ApopBIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|CELL GROWTH AND DEATH|ELECTRON TRANSFER CARRIERS|ENERGY METABOLISM|GENERAL FUNCTION PREDICTION ONLY|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|REPLICATION AND REPAIR|TRANSLATION PROTEINS|XENOBIOTICS BIODEGRADATION AND METABOLISM1- and 2-Methylnaphthalene degradation|Benzoate BIOSYNTHESIS OF SECONDARY METABOLITES|ENERGY METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMAmino sugar and nucleotide sugar metabolism|BenzoaAMINO ACID METABOLISM|BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|XENOBIOTICS BIODEGRADATION AND METABOLISM1- and 2-Methylnaphthalene degradation|3-ChloroaAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|ENERGY METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISMBiosynthesis of unsaturated fatty acids|Fatty acid b LIPID METABOLISMSphingolipid metabolism LIPID METABOLISMGlycine, serine and threonine metabolism AMINO ACID METABOLISMAscorbate and aldarate metabolism CARBOHYDRATE METABOLISMPentose and glucuronate interconversions CARBOHYDRATE METABOLISMAscorbate and aldarate metabolism|Pentose and gluCARBOHYDRATE METABOLISMAmino sugar and nucleotide sugar metabolism|Fr CARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTIONPolyketide sugar unit biosynthesis|Streptomycin bioBIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|BIOSYNTHESIS OF SECONDARY METABOLITESFructose and mannose metabolism CARBOHYDRATE METABOLISMFructose and mannose metabolism CARBOHYDRATE METABOLISMPurine metabolism NUCLEOTIDE METABOLISMBenzoate degradation via CoA ligation|Butanoate CARBOHYDRATE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMAmino sugar and nucleotide sugar metabolism|PeptiCARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISMUnclassified BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITESPantothenate and CoA biosynthesis METABOLISM OF COFACTORS AND VITAMINSFructose and mannose metabolism CARBOHYDRATE METABOLISMSteroid biosynthesis LIPID METABOLISMMetabolism of xenobiotics by cytochrome P450|PenCARBOHYDRATE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMInositol phosphate metabolism|Streptomycin biosynBIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISMPrimary bile acid biosynthesis LIPID METABOLISMArachidonic acid metabolism LIPID METABOLISMRiboflavin metabolism METABOLISM OF COFACTORS AND VITAMINSCaprolactam degradation|Glycerolipid metabolism|GCARBOHYDRATE METABOLISM|LIPID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMGlycerolipid metabolism LIPID METABOLISMDrug metabolism - other enzymes|Purine metaboli NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMFructose and mannose metabolism|Galactose metabCARBOHYDRATE METABOLISM|LIPID METABOLISMUnclassified OTHERSPentose phosphate pathway CARBOHYDRATE METABOLISMFlavonoid biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITESAmino sugar and nucleotide sugar metabolism|AscoCARBOHYDRATE METABOLISMFolate biosynthesis METABOLISM OF COFACTORS AND VITAMINSHistidine metabolism AMINO ACID METABOLISMPhenylalanine, tyrosine and tryptophan biosynthesi AMINO ACID METABOLISM

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Galactose metabolism CARBOHYDRATE METABOLISMGlyoxylate and dicarboxylate metabolism CARBOHYDRATE METABOLISMUnclassified ENERGY METABOLISMVitamin B6 metabolism METABOLISM OF COFACTORS AND VITAMINSUnclassified AMINO ACID METABOLISMTerpenoid backbone biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITESCysteine and methionine metabolism|Glycolysis / AMINO ACID METABOLISM|CARBOHYDRATE METABOLISMAmino sugar and nucleotide sugar metabolism|Fru CARBOHYDRATE METABOLISMCysteine and methionine metabolism AMINO ACID METABOLISMUnclassified OTHERSPyruvate metabolism CARBOHYDRATE METABOLISMPhenylalanine, tyrosine and tryptophan biosynthesi AMINO ACID METABOLISM1- and 2-Methylnaphthalene degradation|3-ChloroaAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|ENERGY METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISMGlycine, serine and threonine metabolism|Glyoxyla AMINO ACID METABOLISM|CARBOHYDRATE METABOLISMVitamin B6 metabolism METABOLISM OF COFACTORS AND VITAMINSCysteine and methionine metabolism|Glycine, serin AMINO ACID METABOLISMButanoate metabolism|Synthesis and degradation oCARBOHYDRATE METABOLISM|LIPID METABOLISMValine, leucine and isoleucine degradation AMINO ACID METABOLISMTerpenoid backbone biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITESAlzheimer's disease|Benzoate degradation via CoA AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|NEURODEGENERATIVE DISEASES|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMButanoate metabolism CARBOHYDRATE METABOLISMCarbon fixation in photosynthetic organisms|Citrat CARBOHYDRATE METABOLISM|ENERGY METABOLISMPyruvate metabolism|Two-component system CARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTIONCarbon fixation in photosynthetic organisms|Pyruv CARBOHYDRATE METABOLISM|ENERGY METABOLISMButanoate metabolism CARBOHYDRATE METABOLISMCarbon fixation in photosynthetic organisms|Pyruv CARBOHYDRATE METABOLISM|ENERGY METABOLISMCitrate cycle (TCA cycle) CARBOHYDRATE METABOLISMCitrate cycle (TCA cycle)|Glutathione metabolism|P CARBOHYDRATE METABOLISM|ENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDS|TRANSPORT AND CATABOLISMGlutathione metabolism|Pentose phosphate pathw CARBOHYDRATE METABOLISM|METABOLISM OF OTHER AMINO ACIDSPentose phosphate pathway CARBOHYDRATE METABOLISMGlutathione metabolism|Pentose phosphate pathw CARBOHYDRATE METABOLISM|METABOLISM OF OTHER AMINO ACIDSButanoate metabolism CARBOHYDRATE METABOLISMSteroid hormone biosynthesis LIPID METABOLISMPentose and glucuronate interconversions CARBOHYDRATE METABOLISMPentose and glucuronate interconversions CARBOHYDRATE METABOLISMGlycerolipid metabolism LIPID METABOLISMGlyoxylate and dicarboxylate metabolism CARBOHYDRATE METABOLISMButanoate metabolism CARBOHYDRATE METABOLISMSteroid biosynthesis|Steroid hormone biosynthesis LIPID METABOLISMVitamin B6 metabolism METABOLISM OF COFACTORS AND VITAMINSFructose and mannose metabolism CARBOHYDRATE METABOLISMUnclassified BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITESGlyoxylate and dicarboxylate metabolism|Pyruvate CARBOHYDRATE METABOLISMGlycine, serine and threonine metabolism|Glyoxyla AMINO ACID METABOLISM|CARBOHYDRATE METABOLISMGlycerophospholipid metabolism LIPID METABOLISMGlycine, serine and threonine metabolism|Glyoxyla AMINO ACID METABOLISM|CARBOHYDRATE METABOLISM

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Butanoate metabolism CARBOHYDRATE METABOLISMValine, leucine and isoleucine biosynthesis AMINO ACID METABOLISMPantothenate and CoA biosynthesis|Valine, leucine AMINO ACID METABOLISM|METABOLISM OF COFACTORS AND VITAMINSPentose and glucuronate interconversions CARBOHYDRATE METABOLISMBiphenyl degradation|Caprolactam degradation|PheAMINO ACID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMUnclassified OTHERSGlyoxylate and dicarboxylate metabolism CARBOHYDRATE METABOLISMGlycerophospholipid metabolism LIPID METABOLISMGlycine, serine and threonine metabolism AMINO ACID METABOLISMPyruvate metabolism CARBOHYDRATE METABOLISMPyruvate metabolism CARBOHYDRATE METABOLISMGlyoxylate and dicarboxylate metabolism|Peroxiso CARBOHYDRATE METABOLISM|TRANSPORT AND CATABOLISMGalactose metabolism CARBOHYDRATE METABOLISMPentose phosphate pathway CARBOHYDRATE METABOLISMGlycerophospholipid metabolism LIPID METABOLISMPyruvate metabolism CARBOHYDRATE METABOLISMBenzoate degradation via hydroxylation|Limonene BIOSYNTHESIS OF SECONDARY METABOLITES|METABOLISM OF OTHER AMINO ACIDS|XENOBIOTICS BIODEGRADATION AND METABOLISMGlycine, serine and threonine metabolism AMINO ACID METABOLISMButanoate metabolism CARBOHYDRATE METABOLISMFructose and mannose metabolism CARBOHYDRATE METABOLISMUnclassified OTHERSPhenylalanine, tyrosine and tryptophan biosynthesi AMINO ACID METABOLISMUnclassified OTHERSPentose phosphate pathway CARBOHYDRATE METABOLISM1,2-Dichloroethane degradation|Butanoate metabo CARBOHYDRATE METABOLISM|ENERGY METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMOxidative phosphorylation|Unclassified ENERGY METABOLISM|OTHERSAlzheimer's disease|Cardiac muscle contraction|HunCIRCULATORY SYSTEM|ENERGY METABOLISM|NEURODEGENERATIVE DISEASESOxidative phosphorylation ENERGY METABOLISMUnclassified OTHERSPhotosynthesis|Photosynthesis proteins ENERGY METABOLISMGlutathione metabolism|Plant-pathogen interactionELECTRON TRANSFER CARRIERS|ENVIRONMENTAL ADAPTATION|METABOLISM OF OTHER AMINO ACIDS|PROTEIN FOLDING AND ASSOCIATED PROCESSINGUnclassified OTHERSGlutathione metabolism|Peroxisome|Unclassified METABOLISM OF OTHER AMINO ACIDS|PROTEIN FOLDING AND ASSOCIATED PROCESSING|TRANSPORT AND CATABOLISMUnclassified INORGANIC ION TRANSPORT AND METABOLISMAmyotrophic lateral sclerosis (ALS)|Methane met AMINO ACID METABOLISM|ENERGY METABOLISM|NEURODEGENERATIVE DISEASES|TRANSPORT AND CATABOLISMAsthma|Methane metabolism|Phenylalanine metabolAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|ENERGY METABOLISM|IMMUNE SYSTEM DISEASES|OTHERSArachidonic acid metabolism|Glutathione metaboli LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDSUnclassified OTHERSGlyoxylate and dicarboxylate metabolism|Methane CARBOHYDRATE METABOLISM|ENERGY METABOLISMUnclassified OTHERSUnclassified ENERGY METABOLISMGlyoxylate and dicarboxylate metabolism|Methane CARBOHYDRATE METABOLISM|ENERGY METABOLISMFolate biosynthesis METABOLISM OF COFACTORS AND VITAMINSTrinitrotoluene degradation XENOBIOTICS BIODEGRADATION AND METABOLISM1- and 2-Methylnaphthalene degradation|BisphenolXENOBIOTICS BIODEGRADATION AND METABOLISM1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DD LIPID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

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1,4-Dichlorobenzene degradation|Benzoate degradaXENOBIOTICS BIODEGRADATION AND METABOLISMTyrosine metabolism AMINO ACID METABOLISMPhenylalanine metabolism AMINO ACID METABOLISM1,4-Dichlorobenzene degradation|Benzoate degradaXENOBIOTICS BIODEGRADATION AND METABOLISMUnclassified OTHERSPhenylalanine metabolism|Tyrosine metabolism|UbiAMINO ACID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS2,4-Dichlorobenzoate degradation|Benzoate degradaXENOBIOTICS BIODEGRADATION AND METABOLISMBiphenyl degradation|gamma-Hexachlorocyclohexa XENOBIOTICS BIODEGRADATION AND METABOLISMTyrosine metabolism AMINO ACID METABOLISMUnclassified BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITESStyrene degradation|Tyrosine metabolism AMINO ACID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMTryptophan metabolism AMINO ACID METABOLISMTryptophan metabolism AMINO ACID METABOLISM2,4-Dichlorobenzoate degradation|Benzoate degradaXENOBIOTICS BIODEGRADATION AND METABOLISMNitrogen metabolism ENERGY METABOLISMUnclassified OTHERSBenzoxazinoid biosynthesis|Brassinosteroid biosyn AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|ENERGY METABOLISM|ENZYME FAMILIES|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISMUnclassified OTHERSBenzoxazinoid biosynthesis|Chromosome|DNA repair AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CANCERS|GLYCAN BIOSYNTHESIS AND METABOLISM|OTHERS|REPLICATION AND REPAIR|TRANSCRIPTIONTaurine and hypotaurine metabolism METABOLISM OF OTHER AMINO ACIDSArginine and proline metabolism AMINO ACID METABOLISMLysine degradation AMINO ACID METABOLISMUnclassified OTHERSPhenylalanine metabolism AMINO ACID METABOLISM1,4-Dichlorobenzene degradation|1- and 2-Methyln AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|ENERGY METABOLISM|ENZYME FAMILIES|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISM1- and 2-Methylnaphthalene degradation|Fluorene XENOBIOTICS BIODEGRADATION AND METABOLISM2,4-Dichlorobenzoate degradation|Benzoate degradaXENOBIOTICS BIODEGRADATION AND METABOLISMCaprolactam degradation XENOBIOTICS BIODEGRADATION AND METABOLISMTyrosine metabolism AMINO ACID METABOLISMArachidonic acid metabolism|Cytochrome P450 ENZYME FAMILIES|LIPID METABOLISMAlzheimer's disease|Amyotrophic lateral sclerosis AMINO ACID METABOLISM|CANCERS|ENVIRONMENTAL ADAPTATION|INFECTIOUS DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|SIGNAL TRANSDUCTION|TRANSPORT AND CATABOLISMLysine degradation AMINO ACID METABOLISMNaphthalene and anthracene degradation|Toluene XENOBIOTICS BIODEGRADATION AND METABOLISMSteroid biosynthesis LIPID METABOLISMPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINS2,4-Dichlorobenzoate degradation XENOBIOTICS BIODEGRADATION AND METABOLISMPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSButirosin and neomycin biosynthesis|Steroid biosyn BIOSYNTHESIS OF SECONDARY METABOLITES|ENERGY METABOLISM|LIPID METABOLISMArachidonic acid metabolism|Caffeine metabolism AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|ENZYME FAMILIES|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISMUnclassified OTHERSUnclassified ENERGY METABOLISMArachidonic acid metabolism|Cytochrome P450|FattCIRCULATORY SYSTEM|ENDOCRINE SYSTEM|ENZYME FAMILIES|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINSPhenylalanine metabolism|Phenylalanine, tyrosine AMINO ACID METABOLISMIsoquinoline alkaloid biosynthesis|Parkinson's dise AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|NEURODEGENERATIVE DISEASESTryptophan metabolism AMINO ACID METABOLISMUnclassified OTHERS

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Betalain biosynthesis|Isoquinoline alkaloid biosy AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|ENDOCRINE SYSTEM|METABOLISM OF COFACTORS AND VITAMINSAmino sugar and nucleotide sugar metabolism CARBOHYDRATE METABOLISMBiosynthesis of unsaturated fatty acids|Lipid bios ENDOCRINE SYSTEM|LIPID METABOLISM|SIGNAL TRANSDUCTIONBiosynthesis of unsaturated fatty acids|Lipid biosy ENDOCRINE SYSTEM|LIPID METABOLISMBiosynthesis of unsaturated fatty acids|Fatty acid b LIPID METABOLISM1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DD BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITES|BIOSYNTHESIS OF SECONDARY METABOLITES|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISMPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSSteroid biosynthesis LIPID METABOLISMAmyotrophic lateral sclerosis (ALS)|Huntington's d INORGANIC ION TRANSPORT AND METABOLISM|NEURODEGENERATIVE DISEASES|TRANSPORT AND CATABOLISMUnclassified ENERGY METABOLISMUnclassified ENERGY METABOLISMUnclassified OTHERSPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSAmino sugar and nucleotide sugar metabolism CARBOHYDRATE METABOLISMTerpenoid backbone biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITESFlavonoid biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITESCaffeine metabolism|Drug metabolism - other enz BIOSYNTHESIS OF SECONDARY METABOLITES|NUCLEOTIDE METABOLISM|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMCaffeine metabolism|Drug metabolism - other enz BIOSYNTHESIS OF SECONDARY METABOLITES|NUCLEOTIDE METABOLISM|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMCytosolic DNA-sensing pathway|DNA repair and rec CELL GROWTH AND DEATH|IMMUNE SYSTEM|METABOLISM OF OTHER AMINO ACIDS|NUCLEOTIDE METABOLISM|REPLICATION AND REPAIRPurine metabolism|Pyrimidine metabolism NUCLEOTIDE METABOLISMTerpenoid backbone biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITESPorphyrin and chlorophyll metabolism|Unclassified METABOLISM OF COFACTORS AND VITAMINS|OTHERSUnclassified ENERGY METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERSFatty acid metabolism LIPID METABOLISMPhotosynthesis|Photosynthesis proteins|Unclassifi ENERGY METABOLISMFatty acid metabolism|Phenylalanine metabolism AMINO ACID METABOLISM|LIPID METABOLISMNitrogen metabolism|Tetrachloroethene degradatioENERGY METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISMNitrogen metabolism ENERGY METABOLISM1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DD BIOSYNTHESIS OF SECONDARY METABOLITES|XENOBIOTICS BIODEGRADATION AND METABOLISM1- and 2-Methylnaphthalene degradation|Arginine AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|ENERGY METABOLISM|OTHERS|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMButanoate metabolism|Pyruvate metabolism CARBOHYDRATE METABOLISMCysteine and methionine metabolism|Glycine, serin AMINO ACID METABOLISMAlzheimer's disease|Glycolysis / Gluconeogenesis|UnCARBOHYDRATE METABOLISM|NEURODEGENERATIVE DISEASES|OTHERSAlanine, aspartate and glutamate metabolism|But AMINO ACID METABOLISM|CARBOHYDRATE METABOLISMArginine and proline metabolism|beta-Alanine met AMINO ACID METABOLISM|METABOLISM OF OTHER AMINO ACIDSGlyoxylate and dicarboxylate metabolism|Methan CARBOHYDRATE METABOLISM|ENERGY METABOLISM|SIGNAL TRANSDUCTIONGlyoxylate and dicarboxylate metabolism|Pyruvate CARBOHYDRATE METABOLISMGlyoxylate and dicarboxylate metabolism|Pyruvate CARBOHYDRATE METABOLISMInositol phosphate metabolism|Propanoate metaboliAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM1,2-Dichloroethane degradation|3-Chloroacrylic a AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|XENOBIOTICS BIODEGRADATION AND METABOLISMLysine biosynthesis|Lysine degradation AMINO ACID METABOLISMArginine and proline metabolism AMINO ACID METABOLISMPhenylalanine metabolism|Styrene degradation AMINO ACID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMArginine and proline metabolism AMINO ACID METABOLISMBenzoate degradation via hydroxylation|Tyrosine m AMINO ACID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

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Unclassified LIPID METABOLISMCarbon fixation in photosynthetic organisms|Glycol CARBOHYDRATE METABOLISM|ENERGY METABOLISMTyrosine metabolism AMINO ACID METABOLISMPhenylpropanoid biosynthesis|Unclassified BIOSYNTHESIS OF SECONDARY METABOLITES|ENERGY METABOLISMPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSArginine and proline metabolism AMINO ACID METABOLISMVitamin B6 metabolism METABOLISM OF COFACTORS AND VITAMINSGlycine, serine and threonine metabolism AMINO ACID METABOLISMGlycolysis / Gluconeogenesis CARBOHYDRATE METABOLISMPyruvate metabolism CARBOHYDRATE METABOLISMDrug metabolism - cytochrome P450|Nicotinate andAMINO ACID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISMPyruvate metabolism CARBOHYDRATE METABOLISMButanoate metabolism|Citrate cycle (TCA cycle)|GlyAMINO ACID METABOLISM|CARBOHYDRATE METABOLISMCitrate cycle (TCA cycle)|Lysine degradation|Trypt AMINO ACID METABOLISM|CARBOHYDRATE METABOLISMValine, leucine and isoleucine degradation AMINO ACID METABOLISMUnclassified ENERGY METABOLISMButanoate metabolism|Citrate cycle (TCA cycle)|Gl CARBOHYDRATE METABOLISM|ENERGY METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMCitrate cycle (TCA cycle)|Reductive carboxylate cycleCARBOHYDRATE METABOLISM|ENERGY METABOLISMMethane metabolism ENERGY METABOLISMGlycolysis / Gluconeogenesis|Pentose phosphate p CARBOHYDRATE METABOLISMGlycolysis / Gluconeogenesis CARBOHYDRATE METABOLISMValine, leucine and isoleucine degradation AMINO ACID METABOLISMUnclassified ENERGY METABOLISMMethane metabolism|Trinitrotoluene degradation ENERGY METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMFolate biosynthesis METABOLISM OF COFACTORS AND VITAMINSUnclassified OTHERSUnclassified OTHERSUnclassified ELECTRON TRANSFER CARRIERSUbiquinone and other terpenoid-quinone biosynthesMETABOLISM OF COFACTORS AND VITAMINSArginine and proline metabolism AMINO ACID METABOLISMUnclassified OTHERSUnclassified OTHERSUnclassified OTHERS1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DDT AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|LIPID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMNovobiocin biosynthesis|Phenylalanine, tyrosine an AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITESDrug metabolism - other enzymes|Pantothenate an METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDS|NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMMetabolism of xenobiotics by cytochrome P450|PenCARBOHYDRATE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMSteroid biosynthesis LIPID METABOLISMPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSBenzoate degradation via CoA ligation|Benzoate de XENOBIOTICS BIODEGRADATION AND METABOLISMLysine biosynthesis AMINO ACID METABOLISMBiosynthesis of siderophore group nonribosomal pe BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDESPrimary bile acid biosynthesis|Steroid hormone biosLIPID METABOLISMPeroxisome|Unclassified ENERGY METABOLISM|TRANSPORT AND CATABOLISMBiosynthesis of unsaturated fatty acids|Fatty acid LIPID METABOLISM|TRANSPORT AND CATABOLISMButanoate metabolism CARBOHYDRATE METABOLISM

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Porphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSUnclassified OTHERSPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSTerpenoid backbone biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITESFatty acid biosynthesis|Lipid biosynthesis proteins LIPID METABOLISMPyrimidine metabolism NUCLEOTIDE METABOLISMUnclassified METABOLISM OF COFACTORS AND VITAMINSPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSBiosynthesis of unsaturated fatty acids|Fatty acid ENDOCRINE SYSTEM|LIPID METABOLISM|TRANSPORT AND CATABOLISMAlzheimer's disease|Citrate cycle (TCA cycle)|Hunti CARBOHYDRATE METABOLISM|ENERGY METABOLISM|NEURODEGENERATIVE DISEASESPyrimidine metabolism NUCLEOTIDE METABOLISM1- and 2-Methylnaphthalene degradation|Benzoate deAMINO ACID METABOLISM|BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITES|BIOSYNTHESIS OF SECONDARY METABOLITES|LIPID METABOLISM|OTHERS|XENOBIOTICS BIODEGRADATION AND METABOLISMBenzoate degradation via CoA ligation|Butanoate mCARBOHYDRATE METABOLISM|ENERGY METABOLISM|SIGNAL TRANSDUCTION|XENOBIOTICS BIODEGRADATION AND METABOLISMValine, leucine and isoleucine degradation AMINO ACID METABOLISMBenzoate degradation via CoA ligation XENOBIOTICS BIODEGRADATION AND METABOLISMUnclassified ENERGY METABOLISMButanoate metabolism|Fatty acid metabolism|ValineAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|LIPID METABOLISMPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSRetinol metabolism METABOLISM OF COFACTORS AND VITAMINSFatty acid metabolism|PPAR signaling pathway|PropAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDSProstate cancer|Steroid hormone biosynthesis CANCERS|LIPID METABOLISMBenzoate degradation via CoA ligation|Fatty acid AMINO ACID METABOLISM|LIPID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMPhenylalanine, tyrosine and tryptophan biosynthesisAMINO ACID METABOLISMAlanine, aspartate and glutamate metabolism|ReducAMINO ACID METABOLISM|ENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDSAlanine, aspartate and glutamate metabolism|Nitr AMINO ACID METABOLISM|ENERGY METABOLISMAlanine, aspartate and glutamate metabolism|Nitr AMINO ACID METABOLISM|ENERGY METABOLISMLysine biosynthesis AMINO ACID METABOLISMAlanine, aspartate and glutamate metabolism|Argi AMINO ACID METABOLISM|ENERGY METABOLISMNicotinate and nicotinamide metabolism METABOLISM OF COFACTORS AND VITAMINSAlanine, aspartate and glutamate metabolism|Argi AMINO ACID METABOLISM|ENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDSAlanine, aspartate and glutamate metabolism|Argi AMINO ACID METABOLISM|ENERGY METABOLISMValine, leucine and isoleucine biosynthesis|Valine, AMINO ACID METABOLISMArginine and proline metabolism|Unclassified AMINO ACID METABOLISM|OTHERSAlanine, aspartate and glutamate metabolism|NicotAMINO ACID METABOLISM|METABOLISM OF COFACTORS AND VITAMINSThiamine metabolism|Unclassified METABOLISM OF COFACTORS AND VITAMINS|OTHERSGlycine, serine and threonine metabolism|IsoquinolAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|METABOLISM OF OTHER AMINO ACIDSArginine and proline metabolism|D-Arginine and D- AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|METABOLISM OF OTHER AMINO ACIDS|TRANSPORT AND CATABOLISMArginine and proline metabolism|Drug metabolism AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|XENOBIOTICS BIODEGRADATION AND METABOLISMVitamin B6 metabolism METABOLISM OF COFACTORS AND VITAMINSGlycine, serine and threonine metabolism AMINO ACID METABOLISMNitrogen metabolism ENERGY METABOLISMNitrogen metabolism|Phenylalanine metabolism AMINO ACID METABOLISM|ENERGY METABOLISMMethane metabolism ENERGY METABOLISMMethane metabolism|Unclassified ENERGY METABOLISM|GENERAL FUNCTION PREDICTION ONLY|OTHERSLysine biosynthesis|Lysine degradation AMINO ACID METABOLISM

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Alanine, aspartate and glutamate metabolism|ArginAMINO ACID METABOLISMArginine and proline metabolism AMINO ACID METABOLISMMethane metabolism|One carbon pool by folate ENERGY METABOLISM|METABOLISM OF COFACTORS AND VITAMINSUnclassified OTHERSButirosin and neomycin biosynthesis|Unclassified BIOSYNTHESIS OF SECONDARY METABOLITES|OTHERSFolate biosynthesis|One carbon pool by folate METABOLISM OF COFACTORS AND VITAMINSFolate biosynthesis|Trinitrotoluene degradation METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISMGlyoxylate and dicarboxylate metabolism|One carboCARBOHYDRATE METABOLISM|METABOLISM OF COFACTORS AND VITAMINSLysine biosynthesis|Lysine degradation AMINO ACID METABOLISMLysine degradation AMINO ACID METABOLISMUnclassified AMINO ACID METABOLISM|OTHERSGlycine, serine and threonine metabolism|Lysine d AMINO ACID METABOLISM|TRANSPORT AND CATABOLISMUnclassified AMINO ACID METABOLISMUnclassified AMINO ACID METABOLISMUnclassified AMINO ACID METABOLISMUnclassified ENERGY METABOLISMUnclassified ENERGY METABOLISMGlycine, serine and threonine metabolism AMINO ACID METABOLISMFolate biosynthesis METABOLISM OF COFACTORS AND VITAMINSZeatin biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITESGlycine, serine and threonine metabolism AMINO ACID METABOLISMArginine and proline metabolism|beta-Alanine met AMINO ACID METABOLISM|METABOLISM OF OTHER AMINO ACIDSArginine and proline metabolism AMINO ACID METABOLISMFolate biosynthesis METABOLISM OF COFACTORS AND VITAMINSUnclassified OTHERSNicotinate and nicotinamide metabolism METABOLISM OF COFACTORS AND VITAMINSNicotinate and nicotinamide metabolism METABOLISM OF COFACTORS AND VITAMINSUnclassified OTHERSPlant-pathogen interaction ENVIRONMENTAL ADAPTATIONUnclassified ELECTRON TRANSFER CARRIERSUnclassified PROTEIN FOLDING AND ASSOCIATED PROCESSINGUnclassified ENERGY METABOLISMUnclassified METABOLISM OF COFACTORS AND VITAMINSAlzheimer's disease|Huntington's disease|OxidativeENERGY METABOLISM|NEURODEGENERATIVE DISEASESUnclassified ENERGY METABOLISMUnclassified OTHERSUnclassified OTHERSUnclassified ENERGY METABOLISMAlzheimer's disease|Huntington's disease|OxidativeENERGY METABOLISM|NEURODEGENERATIVE DISEASESOxidative phosphorylation ENERGY METABOLISMUnclassified ENERGY METABOLISM|OTHERSUnclassified GENERAL FUNCTION PREDICTION ONLYNitrogen metabolism ENERGY METABOLISMPurine metabolism NUCLEOTIDE METABOLISMNitrogen metabolism ENERGY METABOLISMNitrogen metabolism|Unclassified ENERGY METABOLISM|OTHERS

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Two-component system|Unclassified ELECTRON TRANSFER CARRIERS|SIGNAL TRANSDUCTIONCaffeine metabolism|Purine metabolism BIOSYNTHESIS OF SECONDARY METABOLITES|NUCLEOTIDE METABOLISMNitrogen metabolism ENERGY METABOLISMNitrogen metabolism ENERGY METABOLISMNitrogen metabolism|Two-component system ENERGY METABOLISM|SIGNAL TRANSDUCTIONNitrogen metabolism ENERGY METABOLISMNitrogen metabolism ENERGY METABOLISMUnclassified OTHERSUnclassified OTHERSSulfur metabolism ENERGY METABOLISMCitrate cycle (TCA cycle)|Glycine, serine and thre AMINO ACID METABOLISM|CARBOHYDRATE METABOLISMGlutathione metabolism METABOLISM OF OTHER AMINO ACIDSChaperones and folding catalysts|Unclassified FOLDING, SORTING AND DEGRADATION|PROTEIN FOLDING AND ASSOCIATED PROCESSINGPyrimidine metabolism NUCLEOTIDE METABOLISMUnclassified OTHERSUnclassified OTHERSUnclassified OTHERSUnclassified|Vibrio cholerae infection INFECTIOUS DISEASES|OTHERSUnclassified PROTEIN FOLDING AND ASSOCIATED PROCESSINGUnclassified PROTEIN FOLDING AND ASSOCIATED PROCESSINGSulfur metabolism ENERGY METABOLISMFolate biosynthesis METABOLISM OF COFACTORS AND VITAMINSUnclassified ELECTRON TRANSFER CARRIERS|ENERGY METABOLISMSelenoamino acid metabolism|Sulfur metabolism ENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDSTrinitrotoluene degradation XENOBIOTICS BIODEGRADATION AND METABOLISMOxidative phosphorylation ENERGY METABOLISMAlzheimer's disease|Cardiac muscle contraction|HunCIRCULATORY SYSTEM|ENERGY METABOLISM|NEURODEGENERATIVE DISEASESUnclassified PROTEIN FOLDING AND ASSOCIATED PROCESSINGUnclassified AMINO ACID METABOLISMGlycosyltransferases|Lipopolysaccharide biosynthesBIOSYNTHESIS OF SECONDARY METABOLITES|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|OTHERSChromosome|Unclassified GLYCAN BIOSYNTHESIS AND METABOLISM|OTHERS|REPLICATION AND REPAIRBacterial motility proteins|Bacterial secretion s AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CELL MOTILITY|ENZYME FAMILIES|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|MEMBRANE TRANSPORT|METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDS|REPLICATION AND REPAIR|TRANSCRIPTION|TRANSLATION PROTEINS|XENOBIOTICS BIODEGRADATION AND METABOLISMCysteine and methionine metabolism AMINO ACID METABOLISMUnclassified PROTEIN FOLDING AND ASSOCIATED PROCESSINGUnclassified OTHERSGlycerophospholipid metabolism LIPID METABOLISMFlavonoid biosynthesis|Phenylpropanoid biosynthesiBIOSYNTHESIS OF SECONDARY METABOLITESPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSUnclassified REPLICATION, RECOMBINATION AND REPAIR PROTEINSUbiquinone and other terpenoid-quinone biosynthesMETABOLISM OF COFACTORS AND VITAMINSCell cycle - yeast|Chromosome|Spliceosome CELL GROWTH AND DEATH|REPLICATION AND REPAIR|TRANSCRIPTIONCysteine and methionine metabolism|One carbon poAMINO ACID METABOLISM|METABOLISM OF COFACTORS AND VITAMINSPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINS

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Unclassified OTHERSCysteine and methionine metabolism AMINO ACID METABOLISMUnclassified BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITESOne carbon pool by folate|Pyrimidine metabolism METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISMPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSArginine and proline metabolism|Glycine, serine a AMINO ACID METABOLISMUnclassified TRANSLATION PROTEINSUnclassified TRANSLATION PROTEINSUnclassified OTHERSUnclassified TRANSLATION PROTEINSUnclassified TRANSLATION PROTEINSUnclassified TRANSLATION PROTEINSChromosome|Cysteine and methionine metabolism|DAMINO ACID METABOLISM|REPLICATION AND REPAIRSteroid biosynthesis LIPID METABOLISMChromosome|Lysine degradation|Tight junction AMINO ACID METABOLISM|CELL COMMUNICATION|REPLICATION AND REPAIROne carbon pool by folate|Pyrimidine metabolism METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISMUnclassified TRANSLATION PROTEINSUnclassified OTHERSUnclassified TRANSLATION PROTEINSUnclassified OTHERSUnclassified TRANSLATION PROTEINSDNA repair and recombination proteins|TranscriptioREPLICATION AND REPAIR|TRANSCRIPTIONUbiquinone and other terpenoid-quinone biosynthesMETABOLISM OF COFACTORS AND VITAMINSDrug metabolism - other enzymes XENOBIOTICS BIODEGRADATION AND METABOLISMDNA repair and recombination proteins|DNA replicaREPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINS|RESTRICTION ENZYME|TRANSLATION PROTEINSUnclassified PROTEIN FOLDING AND ASSOCIATED PROCESSINGUnclassified MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULESBacterial chemotaxis|Bacterial motility proteins| CELL MOTILITY|SIGNAL TRANSDUCTIONFolate biosynthesis METABOLISM OF COFACTORS AND VITAMINSUnclassified OTHERSUnclassified TRANSLATION PROTEINSAmino sugar and nucleotide sugar metabolism|LipopoCARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|OTHERSCyanoamino acid metabolism|Glycine, serine and AMINO ACID METABOLISM|ENERGY METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDSGlycine, serine and threonine metabolism|Nitrogen AMINO ACID METABOLISM|ENERGY METABOLISM|METABOLISM OF COFACTORS AND VITAMINSPantothenate and CoA biosynthesis METABOLISM OF COFACTORS AND VITAMINSOne carbon pool by folate|Purine metabolism METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISMOne carbon pool by folate|Purine metabolism METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISMHistidine metabolism|One carbon pool by folate AMINO ACID METABOLISM|METABOLISM OF COFACTORS AND VITAMINSAminoacyl-tRNA biosynthesis|One carbon pool by foMETABOLISM OF COFACTORS AND VITAMINS|TRANSLATIONPenicillin and cephalosporin biosynthesis|Unclassifi BIOSYNTHESIS OF SECONDARY METABOLITES|PROTEIN FOLDING AND ASSOCIATED PROCESSINGUnclassified AMINO ACID METABOLISMAlanine, aspartate and glutamate metabolism|Pept AMINO ACID METABOLISM|ENZYME FAMILIES|NUCLEOTIDE METABOLISMArginine and proline metabolism AMINO ACID METABOLISMUnclassified AMINO ACID METABOLISMBiosynthesis of ansamycins|Carbon fixation in pho BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|CARBOHYDRATE METABOLISM|ENERGY METABOLISM

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Pentose phosphate pathway CARBOHYDRATE METABOLISMButanoate metabolism|C5-Branched dibasic acid metAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|METABOLISM OF COFACTORS AND VITAMINSTerpenoid backbone biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITESUbiquinone and other terpenoid-quinone biosynthesMETABOLISM OF COFACTORS AND VITAMINS1- and 2-Methylnaphthalene degradation|AnthocyaniAMINO ACID METABOLISM|BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GENERAL FUNCTION PREDICTION ONLY|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|MEMBRANE TRANSPORT|OTHERS|PROTEIN FOLDING AND ASSOCIATED PROCESSING|REPLICATION AND REPAIR|TRANSLATION PROTEINS|XENOBIOTICS BIODEGRADATION AND METABOLISMArginine and proline metabolism AMINO ACID METABOLISMFolate biosynthesis|Methane metabolism ENERGY METABOLISM|METABOLISM OF COFACTORS AND VITAMINSArginine and proline metabolism AMINO ACID METABOLISMLysine biosynthesis AMINO ACID METABOLISMUnclassified BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITESCitrate cycle (TCA cycle)|Glycolysis / Gluconeogen CARBOHYDRATE METABOLISMUnclassified TRANSLATION PROTEINSLipopolysaccharide biosynthesis|LipopolysaccharideGLYCAN BIOSYNTHESIS AND METABOLISMPeroxisome TRANSPORT AND CATABOLISMGlycerolipid metabolism|Glycerophospholipid metabLIPID METABOLISMAmino sugar and nucleotide sugar metabolism CARBOHYDRATE METABOLISMGlycerolipid metabolism LIPID METABOLISMBenzoate degradation via hydroxylation|BiosynthesiAMINO ACID METABOLISM|ENDOCRINE SYSTEM|LIPID METABOLISM|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMPenicillin and cephalosporin biosynthesis|Peptidase BIOSYNTHESIS OF SECONDARY METABOLITES|ENZYME FAMILIESValine, leucine and isoleucine degradation AMINO ACID METABOLISMMethane metabolism ENERGY METABOLISMPPAR signaling pathway|Peroxisome|Primary bile acENDOCRINE SYSTEM|LIPID METABOLISM|TRANSPORT AND CATABOLISMGlycine, serine and threonine metabolism AMINO ACID METABOLISMFatty acid biosynthesis|Lipid biosynthesis proteins LIPID METABOLISMUnclassified OTHERSFatty acid biosynthesis|Lipid biosynthesis proteins LIPID METABOLISMLipoic acid metabolism METABOLISM OF COFACTORS AND VITAMINSValine, leucine and isoleucine biosynthesis AMINO ACID METABOLISMPhosphonate and phosphinate metabolism METABOLISM OF OTHER AMINO ACIDSButanoate metabolism CARBOHYDRATE METABOLISMGlycerolipid metabolism|Retinol metabolism LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINSAdipocytokine signaling pathway|Fatty acid metabo ENDOCRINE SYSTEM|LIPID METABOLISMEther lipid metabolism|Glycerolipid metabolism|GlyLIPID METABOLISMSteroid biosynthesis LIPID METABOLISMUnclassified OTHERSGlycine, serine and threonine metabolism AMINO ACID METABOLISMCysteine and methionine metabolism|Sulfur metab AMINO ACID METABOLISM|ENERGY METABOLISMCysteine and methionine metabolism|Sulfur metab AMINO ACID METABOLISM|ENERGY METABOLISMArginine and proline metabolism AMINO ACID METABOLISMGlycine, serine and threonine metabolism|Porphyri AMINO ACID METABOLISM|METABOLISM OF COFACTORS AND VITAMINSFatty acid biosynthesis|Lipid biosynthesis proteins LIPID METABOLISMAmino sugar and nucleotide sugar metabolism CARBOHYDRATE METABOLISMFatty acid biosynthesis|Lipid biosynthesis proteins LIPID METABOLISMGlycerolipid metabolism|Glycerophospholipid metabLIPID METABOLISM|TRANSPORT AND CATABOLISMGlycerophospholipid metabolism LIPID METABOLISMCysteine and methionine metabolism|Sulfur metab AMINO ACID METABOLISM|ENERGY METABOLISM

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Biotin metabolism METABOLISM OF COFACTORS AND VITAMINSAdherens junction|Cell cycle|Chromosome|CircadianCANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|ENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|OTHERS|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|TRANSCRIPTIONSphingolipid metabolism LIPID METABOLISMEther lipid metabolism|Glycerolipid metabolism|GlyLIPID METABOLISMButanoate metabolism|Propanoate metabolism|PyrCARBOHYDRATE METABOLISMArginine and proline metabolism AMINO ACID METABOLISMCitrate cycle (TCA cycle)|Lysine degradation AMINO ACID METABOLISM|CARBOHYDRATE METABOLISMEther lipid metabolism|Glycerophospholipid metabolLIPID METABOLISMPeroxisome TRANSPORT AND CATABOLISMGlycosaminoglycan degradation|Lysosome GLYCAN BIOSYNTHESIS AND METABOLISM|TRANSPORT AND CATABOLISMUnclassified OTHERSPropanoate metabolism|Pyruvate metabolism|TaurCARBOHYDRATE METABOLISM|METABOLISM OF OTHER AMINO ACIDSUnclassified OTHERSUnclassified OTHERSFatty acid biosynthesis|Insulin signaling pathway|Li ENDOCRINE SYSTEM|LIPID METABOLISMFatty acid biosynthesis|Lipid biosynthesis proteins LIPID METABOLISMTryptophan metabolism AMINO ACID METABOLISMUnclassified OTHERSBenzoate degradation via CoA ligation|Butanoate AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|LIPID METABOLISM|SIGNAL TRANSDUCTION|XENOBIOTICS BIODEGRADATION AND METABOLISMBiosynthesis of 12-, 14- and 16-membered macrolideBIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|LIPID METABOLISMUnclassified OTHERSButirosin and neomycin biosynthesis|Peptidoglycan BIOSYNTHESIS OF SECONDARY METABOLITES|GLYCAN BIOSYNTHESIS AND METABOLISMPeptidoglycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISMCAM ligands|Complement and coagulation cascades|IMMUNE SYSTEM|NEURODEGENERATIVE DISEASES|OTHERS|SIGNALING MOLECULES AND INTERACTION|SPORULATIONArachidonic acid metabolism|Cellular antigens|Cy ENZYME FAMILIES|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|SIGNALING MOLECULES AND INTERACTIONGlutathione metabolism METABOLISM OF OTHER AMINO ACIDSUnclassified OTHERSUnclassified PROTEIN FOLDING AND ASSOCIATED PROCESSINGUnclassified PROTEIN FOLDING AND ASSOCIATED PROCESSINGCitrate cycle (TCA cycle)|Glyoxylate and dicarboxyl CARBOHYDRATE METABOLISMButanoate metabolism|Synthesis and degradation ofAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|LIPID METABOLISMPyruvate metabolism|Valine, leucine and isoleucine AMINO ACID METABOLISM|CARBOHYDRATE METABOLISMLysine biosynthesis|Pyruvate metabolism AMINO ACID METABOLISM|CARBOHYDRATE METABOLISMPropanoate metabolism CARBOHYDRATE METABOLISMCitrate cycle (TCA cycle)|Reductive carboxylate cycleCARBOHYDRATE METABOLISM|ENERGY METABOLISMGlyoxylate and dicarboxylate metabolism|Pyruvate CARBOHYDRATE METABOLISMLipopolysaccharide biosynthesis|Lipopolysaccharide GLYCAN BIOSYNTHESIS AND METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|OTHERSAnthocyanin biosynthesis|Butirosin and neomycin biBIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|CELLULAR PROCESSES AND SIGNALING|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|SIGNALING MOLECULES AND INTERACTIONInsulin signaling pathway|Starch and sucrose metabCARBOHYDRATE METABOLISM|ENDOCRINE SYSTEMStarch and sucrose metabolism|Two-component sy CARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTIONGlycosyltransferases|N-Glycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISMGlycosyltransferases|O-Mannosyl glycan biosynthesGLYCAN BIOSYNTHESIS AND METABOLISMGlycosyltransferases|Insulin signaling pathway|Sta CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|GLYCAN BIOSYNTHESIS AND METABOLISMGlycosyltransferases|N-Glycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISMGlycosyltransferases|N-Glycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISMGlycosyltransferases|Starch and sucrose metabolis CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM

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Chromosome|Peptidoglycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISM|REPLICATION AND REPAIRStarch and sucrose metabolism CARBOHYDRATE METABOLISMGlycosyltransferases|N-Glycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISMGlycosyltransferases|N-Glycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISMGlycosaminoglycan biosynthesis - chondroitin sulfa GLYCAN BIOSYNTHESIS AND METABOLISMGlycosaminoglycan biosynthesis - chondroitin sulfa GLYCAN BIOSYNTHESIS AND METABOLISMCellular antigens|Glycosaminoglycan biosynthesis - GLYCAN BIOSYNTHESIS AND METABOLISM|SIGNALING MOLECULES AND INTERACTIONStarch and sucrose metabolism CARBOHYDRATE METABOLISMGlycosyltransferases|N-Glycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISMGlycosyltransferases|N-Glycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISMGlycosyltransferases|N-Glycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISMGlycosyltransferases|O-Glycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISMStarch and sucrose metabolism CARBOHYDRATE METABOLISMGlycosphingolipid biosynthesis - lacto and neolacto GLYCAN BIOSYNTHESIS AND METABOLISMGlycosphingolipid biosynthesis - globo series|GlycosGLYCAN BIOSYNTHESIS AND METABOLISMGlycerolipid metabolism|Glycosyltransferases GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISMAmino sugar and nucleotide sugar metabolism|GlycoCARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISMUnclassified OTHERSAscorbate and aldarate metabolism|Drug metabolisCARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISMGlycosyltransferases GLYCAN BIOSYNTHESIS AND METABOLISMGlycosaminoglycan biosynthesis - chondroitin sulfat GLYCAN BIOSYNTHESIS AND METABOLISMGlycosaminoglycan biosynthesis - chondroitin sulfat GLYCAN BIOSYNTHESIS AND METABOLISMStarch and sucrose metabolism CARBOHYDRATE METABOLISMLipopolysaccharide biosynthesis|LipopolysaccharideGLYCAN BIOSYNTHESIS AND METABOLISMUnclassified OTHERSGlycosyltransferases GLYCAN BIOSYNTHESIS AND METABOLISMUnclassified OTHERSUnclassified OTHERSGlycosylphosphatidylinositol(GPI)-anchor biosynthesGLYCAN BIOSYNTHESIS AND METABOLISMStarch and sucrose metabolism CARBOHYDRATE METABOLISMStarch and sucrose metabolism CARBOHYDRATE METABOLISMUnclassified OTHERSUnclassified CARBOHYDRATE METABOLISMGlycosyltransferases|N-Glycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISMUnclassified CARBOHYDRATE METABOLISMGlycosyltransferases GLYCAN BIOSYNTHESIS AND METABOLISMGlycosaminoglycan biosynthesis - chondroitin sulfat GLYCAN BIOSYNTHESIS AND METABOLISMPeptidoglycan biosynthesis|Unclassified GLYCAN BIOSYNTHESIS AND METABOLISM|OTHERSUnclassified OTHERSGlycosyltransferases|High-mannose type N-glycan bGLYCAN BIOSYNTHESIS AND METABOLISMUnclassified CARBOHYDRATE METABOLISMStarch and sucrose metabolism CARBOHYDRATE METABOLISMStarch and sucrose metabolism CARBOHYDRATE METABOLISMGlycosphingolipid biosynthesis - lacto and neolacto GLYCAN BIOSYNTHESIS AND METABOLISMStarch and sucrose metabolism CARBOHYDRATE METABOLISMGlycosphingolipid biosynthesis - lacto and neolacto GLYCAN BIOSYNTHESIS AND METABOLISM

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Glycosyltransferases|O-Glycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISMStarch and sucrose metabolism|Two-component sy CARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTIONGlycosyltransferases GLYCAN BIOSYNTHESIS AND METABOLISMGlycosyltransferases|Lipopolysaccharide biosynthesiGLYCAN BIOSYNTHESIS AND METABOLISM|OTHERSGlycosyltransferases GLYCAN BIOSYNTHESIS AND METABOLISMGlycosyltransferases|Lipopolysaccharide biosynthesiGLYCAN BIOSYNTHESIS AND METABOLISM|OTHERSGalactose metabolism CARBOHYDRATE METABOLISMGlycosaminoglycan biosynthesis - keratan sulfate|G GLYCAN BIOSYNTHESIS AND METABOLISMStarch and sucrose metabolism CARBOHYDRATE METABOLISMGlycosphingolipid biosynthesis - globo series|GlycosGLYCAN BIOSYNTHESIS AND METABOLISMStarch and sucrose metabolism CARBOHYDRATE METABOLISMGlycosyltransferases|Sphingolipid metabolism GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISMGlycosyltransferases|N-Glycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISMGlycosphingolipid biosynthesis - lacto and neolacto GLYCAN BIOSYNTHESIS AND METABOLISMGlycosphingolipid biosynthesis - globo series|GlycosGLYCAN BIOSYNTHESIS AND METABOLISMUnclassified OTHERSGlycosphingolipid biosynthesis - ganglio series|Glyc GLYCAN BIOSYNTHESIS AND METABOLISMBacterial toxins|Butirosin and neomycin biosynthes AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|GLYCAN BIOSYNTHESIS AND METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISM|OTHERS|SIGNALING MOLECULES AND INTERACTION|TRANSLATION PROTEINSNicotinate and nicotinamide metabolism|Purine meMETABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISMDrug metabolism - other enzymes|Pyrimidine meta NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMNicotinate and nicotinamide metabolism METABOLISM OF COFACTORS AND VITAMINSNicotinate and nicotinamide metabolism METABOLISM OF COFACTORS AND VITAMINSAlanine, aspartate and glutamate metabolism|Pept AMINO ACID METABOLISM|ENZYME FAMILIES|NUCLEOTIDE METABOLISMHistidine metabolism AMINO ACID METABOLISMPhenylalanine, tyrosine and tryptophan biosynthesi AMINO ACID METABOLISMNicotinate and nicotinamide metabolism METABOLISM OF COFACTORS AND VITAMINSPyrimidine metabolism NUCLEOTIDE METABOLISMPorphyrin and chlorophyll metabolism|Riboflavin m METABOLISM OF COFACTORS AND VITAMINSPurine metabolism NUCLEOTIDE METABOLISMGlycosaminoglycan biosynthesis - chondroitin sulfa GLYCAN BIOSYNTHESIS AND METABOLISMCysteine and methionine metabolism AMINO ACID METABOLISMUnclassified TRANSLATION PROTEINSDrug metabolism - other enzymes|Pyrimidine meta NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMBase excision repair|DNA repair and recombination REPLICATION AND REPAIRCellular antigens|Chromosome|Unclassified NUCLEOTIDE METABOLISM|REPLICATION AND REPAIR|SIGNALING MOLECULES AND INTERACTIONUnclassified OTHERSGlycosyltransferases GLYCAN BIOSYNTHESIS AND METABOLISMBladder cancer|Drug metabolism - other enzymes|PCANCERS|NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMPyrimidine metabolism NUCLEOTIDE METABOLISMPurine metabolism NUCLEOTIDE METABOLISMDrug metabolism - other enzymes|Purine metaboli NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMPyrimidine metabolism|Transcription factors NUCLEOTIDE METABOLISM|TRANSCRIPTIONGlycosphingolipid biosynthesis - ganglio series|Glyc GLYCAN BIOSYNTHESIS AND METABOLISMCellular antigens|Glycosyltransferases|N-Glycan bioGLYCAN BIOSYNTHESIS AND METABOLISM|SIGNALING MOLECULES AND INTERACTIONGlycosyltransferases|O-Glycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISMCarotenoid biosynthesis|Cysteine and methionine mAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|ENERGY METABOLISM|METABOLISM OF COFACTORS AND VITAMINS

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Terpenoid backbone biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITESTerpenoid backbone biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITESFolate biosynthesis METABOLISM OF COFACTORS AND VITAMINSArginine and proline metabolism|Cysteine and met AMINO ACID METABOLISM|METABOLISM OF OTHER AMINO ACIDSPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSDrug metabolism - cytochrome P450|Glutathione mMETABOLISM OF OTHER AMINO ACIDS|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMPhenylalanine, tyrosine and tryptophan biosynthesi AMINO ACID METABOLISMSteroid biosynthesis LIPID METABOLISMEther lipid metabolism|Peroxisome LIPID METABOLISM|TRANSPORT AND CATABOLISMTerpenoid backbone biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITESThiamine metabolism METABOLISM OF COFACTORS AND VITAMINSTerpenoid backbone biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITESTerpenoid backbone biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITESCarotenoid biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITESUnclassified OTHERSTropane, piperidine and pyridine alkaloid biosynthesBIOSYNTHESIS OF SECONDARY METABOLITESUnclassified TRANSLATION PROTEINSCyanoamino acid metabolism|Cysteine and methionAMINO ACID METABOLISM|ENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDSCysteine and methionine metabolism|Selenoamino AMINO ACID METABOLISM|ENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDSCysteine and methionine metabolism AMINO ACID METABOLISMPhenylalanine, tyrosine and tryptophan biosynthesi AMINO ACID METABOLISMLipopolysaccharide biosynthesis|LipopolysaccharideGLYCAN BIOSYNTHESIS AND METABOLISMAmino sugar and nucleotide sugar metabolism CARBOHYDRATE METABOLISMUnclassified OTHERSUnclassified OTHERSCysteine and methionine metabolism|Selenoamino AMINO ACID METABOLISM|METABOLISM OF OTHER AMINO ACIDSUnclassified OTHERSPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSAmino sugar and nucleotide sugar metabolism|PeptiCARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISMNicotinate and nicotinamide metabolism METABOLISM OF COFACTORS AND VITAMINSAminoacyl-tRNA biosynthesis TRANSLATIONZeatin biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITESRiboflavin metabolism METABOLISM OF COFACTORS AND VITAMINSGlycosylphosphatidylinositol(GPI)-anchor biosynthe GLYCAN BIOSYNTHESIS AND METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERSAmino sugar and nucleotide sugar metabolism|ArginAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|SIGNAL TRANSDUCTIONAlanine, aspartate and glutamate metabolism|ArginAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|ENERGY METABOLISMArginine and proline metabolism|Lysine biosynthesi AMINO ACID METABOLISMArginine and proline metabolism AMINO ACID METABOLISMAlanine, aspartate and glutamate metabolism|AminAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|ENZYME FAMILIESArginine and proline metabolism|Lysine biosynthesi AMINO ACID METABOLISMPropanoate metabolism|Valine, leucine and isoleuc AMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|METABOLISM OF OTHER AMINO ACIDSAlanine, aspartate and glutamate metabolism|Buta AMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|METABOLISM OF OTHER AMINO ACIDSAlanine, aspartate and glutamate metabolism|CarbonAMINO ACID METABOLISM|ENERGY METABOLISMArginine and proline metabolism|D-Alanine metaboAMINO ACID METABOLISM|METABOLISM OF OTHER AMINO ACIDSAlanine, aspartate and glutamate metabolism|Buta AMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|METABOLISM OF OTHER AMINO ACIDS

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Phosphonate and phosphinate metabolism METABOLISM OF OTHER AMINO ACIDSLysine biosynthesis|Lysine degradation AMINO ACID METABOLISMPantothenate and CoA biosynthesis|Valine, leucine aAMINO ACID METABOLISM|METABOLISM OF COFACTORS AND VITAMINSAlanine, aspartate and glutamate metabolism|Glyci AMINO ACID METABOLISMCysteine and methionine metabolism|Isoquinoline aAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|METABOLISM OF COFACTORS AND VITAMINSGlycine, serine and threonine metabolism|Vitamin AMINO ACID METABOLISM|METABOLISM OF COFACTORS AND VITAMINSCysteine and methionine metabolism|Isoquinoline aAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITESBiotin metabolism METABOLISM OF COFACTORS AND VITAMINSValine, leucine and isoleucine biosynthesis AMINO ACID METABOLISMTryptophan metabolism AMINO ACID METABOLISMGlycine, serine and threonine metabolism AMINO ACID METABOLISMArginine and proline metabolism AMINO ACID METABOLISMArginine and proline metabolism AMINO ACID METABOLISMLysine biosynthesis AMINO ACID METABOLISMFolate biosynthesis METABOLISM OF COFACTORS AND VITAMINSUnclassified AMINO ACID METABOLISMHistidine metabolism|Novobiocin biosynthesis|PhenAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITESVitamin B6 metabolism METABOLISM OF COFACTORS AND VITAMINSGlycosylphosphatidylinositol(GPI)-anchor biosynth AMINO ACID METABOLISM|CELLULAR PROCESSES AND SIGNALING|GLYCAN BIOSYNTHESIS AND METABOLISM|SIGNAL TRANSDUCTIONGlycerolipid metabolism|Lipopolysaccharide biosyn CARBOHYDRATE METABOLISM|FUNCTION UNKNOWN|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|SIGNAL TRANSDUCTION MECHANISMS|TRANSLATION PROTEINSAmino sugar and nucleotide sugar metabolism|ButirBIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|METABOLIC DISEASESCysteine and methionine metabolism AMINO ACID METABOLISMFructose and mannose metabolism CARBOHYDRATE METABOLISMGlycerolipid metabolism|Glycerophospholipid metabLIPID METABOLISM|SIGNAL TRANSDUCTIONN-Glycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISMFructose and mannose metabolism|Galactose metabCARBOHYDRATE METABOLISMPurine metabolism NUCLEOTIDE METABOLISMPentose phosphate pathway CARBOHYDRATE METABOLISMCalcium signaling pathway|Inositol phosphate metabCARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTIONLipopolysaccharide biosynthesis|LipopolysaccharideGLYCAN BIOSYNTHESIS AND METABOLISMInositol phosphate metabolism|PhosphatidylinositolCARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTION|TRANSPORT AND CATABOLISMCarbon fixation in photosynthetic organisms ENERGY METABOLISMGalactose metabolism CARBOHYDRATE METABOLISMUnclassified OTHERSTerpenoid backbone biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITESInositol phosphate metabolism|Phosphatidylinositol CARBOHYDRATE METABOLISM|CELL MOTILITY|SIGNAL TRANSDUCTIONPentose phosphate pathway CARBOHYDRATE METABOLISMAcute myeloid leukemia|Aldosterone-regulated sodiCANCERS|CARBOHYDRATE METABOLISM|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|ENDOCRINE SYSTEM|EXCRETORY SYSTEM|IMMUNE SYSTEM|METABOLIC DISEASES|NERVOUS SYSTEM|SIGNAL TRANSDUCTIONInositol phosphate metabolism|PhosphatidylinositolCARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTIONPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSPentose and glucuronate interconversions CARBOHYDRATE METABOLISMRiboflavin metabolism METABOLISM OF COFACTORS AND VITAMINSUnclassified CARBOHYDRATE METABOLISMAminoacyl-tRNA biosynthesis TRANSLATIONPentose and glucuronate interconversions CARBOHYDRATE METABOLISMCarbon fixation in photosynthetic organisms ENERGY METABOLISM

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Amino sugar and nucleotide sugar metabolism|ButirBIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|METABOLIC DISEASESPurine metabolism NUCLEOTIDE METABOLISMDrug metabolism - other enzymes|Pyrimidine meta NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMNicotinate and nicotinamide metabolism METABOLISM OF COFACTORS AND VITAMINSPantothenate and CoA biosynthesis METABOLISM OF COFACTORS AND VITAMINSPurine metabolism|Selenoamino acid metabolism|SENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDS|NUCLEOTIDE METABOLISMRiboflavin metabolism METABOLISM OF COFACTORS AND VITAMINSGlycerolipid metabolism|RIG-I-like receptor signali IMMUNE SYSTEM|LIPID METABOLISMGlycerolipid metabolism|PPAR signaling pathway|PlENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|LIPID METABOLISMGlycerolipid metabolism|Glycine, serine and threo AMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|LIPID METABOLISMGlycerophospholipid metabolism LIPID METABOLISMBiotin metabolism|Pantothenate and CoA biosyntheMETABOLISM OF COFACTORS AND VITAMINSVitamin B6 metabolism METABOLISM OF COFACTORS AND VITAMINSPeroxisome|Terpenoid backbone biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITES|TRANSPORT AND CATABOLISMUnclassified SIGNAL TRANSDUCTION MECHANISMSGlycine, serine and threonine metabolism AMINO ACID METABOLISMAmino sugar and nucleotide sugar metabolism|Fru CARBOHYDRATE METABOLISMCarbon fixation in photosynthetic organisms|Glycol CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|ENERGY METABOLISM|METABOLIC DISEASES|NUCLEOTIDE METABOLISMGlycolysis / Gluconeogenesis|Starch and sucrose m CARBOHYDRATE METABOLISMPentose and glucuronate interconversions|Pentose CARBOHYDRATE METABOLISMDrug metabolism - other enzymes|Pyrimidine meta NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMThiamine metabolism METABOLISM OF COFACTORS AND VITAMINSFructose and mannose metabolism|Pentose and glucCARBOHYDRATE METABOLISMThiamine metabolism METABOLISM OF COFACTORS AND VITAMINSFructose and mannose metabolism CARBOHYDRATE METABOLISMAmino sugar and nucleotide sugar metabolism|Fru CARBOHYDRATE METABOLISMAscorbate and aldarate metabolism|Pentose and gluCARBOHYDRATE METABOLISMUnclassified OTHERSFructose and mannose metabolism CARBOHYDRATE METABOLISMGalactose metabolism CARBOHYDRATE METABOLISMAmino sugar and nucleotide sugar metabolism CARBOHYDRATE METABOLISMAmino sugar and nucleotide sugar metabolism|GalaCARBOHYDRATE METABOLISMAmino sugar and nucleotide sugar metabolism CARBOHYDRATE METABOLISMAmino sugar and nucleotide sugar metabolism|GlycoCARBOHYDRATE METABOLISMInositol phosphate metabolism|PhosphatidylinositolCARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTIONEndocytosis|Fc gamma R-mediated phagocytosis|InosCARBOHYDRATE METABOLISM|CELL MOTILITY|IMMUNE SYSTEM|SIGNAL TRANSDUCTION|TRANSPORT AND CATABOLISMAmino sugar and nucleotide sugar metabolism|AscoCARBOHYDRATE METABOLISM|MEMBRANE TRANSPORT|UNPROCESSEDPhenylalanine, tyrosine and tryptophan biosynthesi AMINO ACID METABOLISMPurine metabolism NUCLEOTIDE METABOLISMPurine metabolism|Pyrimidine metabolism NUCLEOTIDE METABOLISMGlycerophospholipid metabolism LIPID METABOLISMThiamine metabolism METABOLISM OF COFACTORS AND VITAMINSFructose and mannose metabolism CARBOHYDRATE METABOLISMCalcium signaling pathway|Fc gamma R-mediated phIMMUNE SYSTEM|LIPID METABOLISM|SIGNAL TRANSDUCTIONInositol phosphate metabolism CARBOHYDRATE METABOLISMUnclassified TRANSLATION PROTEINS

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Unclassified SIGNAL TRANSDUCTION MECHANISMSAcute myeloid leukemia|Adherens junction|AldosterCANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|DEVELOPMENT|ENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|ENZYME FAMILIES|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|METABOLIC DISEASES|NERVOUS SYSTEM|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMS|SIGNALING MOLECULES AND INTERACTION|TRANSPORT AND CATABOLISMAdherens junction|Adipocytokine signaling pathway|CANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY DISEASES|DEVELOPMENT|ENDOCRINE SYSTEM|ENZYME FAMILIES|IMMUNE SYSTEM|IMMUNE SYSTEM DISEASES|INFECTIOUS DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMS|SIGNALING MOLECULES AND INTERACTION|TRANSPORT AND CATABOLISMCell cycle - yeast|DNA repair and recombination pr CELL GROWTH AND DEATH|ENZYME FAMILIES|MEMBRANE TRANSPORT|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMSAcute myeloid leukemia|Adherens junction|AdipocytCANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY DISEASES|CIRCULATORY SYSTEM|DEVELOPMENT|ENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|ENZYME FAMILIES|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|MEMBRANE TRANSPORT|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMS|SIGNALING MOLECULES AND INTERACTION|SPORULATION|TRANSCRIPTION|TRANSPORT AND CATABOLISMAcute myeloid leukemia|Adipocytokine signaling patCANCERS|CELL GROWTH AND DEATH|ENDOCRINE SYSTEM|ENZYME FAMILIES|IMMUNE SYSTEM|INFECTIOUS DISEASES|METABOLIC DISEASES|NERVOUS SYSTEM|SIGNAL TRANSDUCTIONAdipocytokine signaling pathway|Apoptosis|Calciu CELL COMMUNICATION|CELL GROWTH AND DEATH|CIRCULATORY DISEASES|CIRCULATORY SYSTEM|ENDOCRINE SYSTEM|ENZYME FAMILIES|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|SENSORY SYSTEM|SIGNAL TRANSDUCTION|TRANSPORT AND CATABOLISMGap junction|Long-term depression|Olfactory trans CELL COMMUNICATION|ENZYME FAMILIES|NERVOUS SYSTEM|SENSORY SYSTEMAldosterone-regulated sodium reabsorption|CalciumCANCERS|CELL COMMUNICATION|CIRCULATORY SYSTEM|ENDOCRINE SYSTEM|ENZYME FAMILIES|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|NERVOUS SYSTEM|SIGNAL TRANSDUCTION|TRANSPORT AND CATABOLISMChemokine signaling pathway|Endocytosis|Protein ENZYME FAMILIES|IMMUNE SYSTEM|TRANSPORT AND CATABOLISMAdipocytokine signaling pathway|Calcium signalin CANCERS|CELL GROWTH AND DEATH|ENDOCRINE SYSTEM|ENZYME FAMILIES|NERVOUS SYSTEM|SENSORY SYSTEM|SIGNAL TRANSDUCTIONCalcium signaling pathway|Focal adhesion|Protein kCELL COMMUNICATION|CELL MOTILITY|CIRCULATORY SYSTEM|ENZYME FAMILIES|SIGNAL TRANSDUCTIONFc epsilon RI signaling pathway|Neurotrophin signalENZYME FAMILIES|IMMUNE SYSTEM|NERVOUS SYSTEMCell cycle|Cell cycle - yeast|Chromosome|Meiosis CELL GROWTH AND DEATH|ENDOCRINE SYSTEM|ENZYME FAMILIES|REPLICATION AND REPAIRAlzheimer's disease|Axon guidance|Bladder cancer|CANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|DEVELOPMENT|ENDOCRINE SYSTEM|ENZYME FAMILIES|IMMUNE SYSTEM|NEURODEGENERATIVE DISEASES|REPLICATION AND REPAIR|TRANSCRIPTIONAcute myeloid leukemia|Adherens junction|AdipocytCANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY SYSTEM|DEVELOPMENT|ENDOCRINE SYSTEM|ENZYME FAMILIES|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|METABOLIC DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|SIGNALING MOLECULES AND INTERACTIONAdherens junction|Amyotrophic lateral sclerosis (A CELL COMMUNICATION|CELL GROWTH AND DEATH|ENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|INFECTIOUS DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|SIGNAL TRANSDUCTIONAdherens junction|Cellular antigens|Chronic myelo CANCERS|CELL COMMUNICATION|ENZYME FAMILIES|SIGNAL TRANSDUCTION|SIGNALING MOLECULES AND INTERACTION|TRANSPORT AND CATABOLISMMAPK signaling pathway|Protein kinases|Unclassifi ENZYME FAMILIES|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMSCell cycle|Cell cycle - yeast|Chromosome|Protein k CELL GROWTH AND DEATH|ENZYME FAMILIES|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION MECHANISMS|TRANSCRIPTIONAcute myeloid leukemia|Amyotrophic lateral sclerosCANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY SYSTEM|DEVELOPMENT|ENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|ENZYME FAMILIES|IMMUNE SYSTEM|INFECTIOUS DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|SIGNAL TRANSDUCTIONProtein kinases|Secretion system|Two-component ENZYME FAMILIES|MEMBRANE TRANSPORT|SIGNAL TRANSDUCTIONUnclassified SIGNAL TRANSDUCTION MECHANISMSBacterial chemotaxis|Bacterial motility proteins|M CELL MOTILITY|ENZYME FAMILIES|INFECTIOUS DISEASES|OTHERS|SIGNAL TRANSDUCTIONLysine biosynthesis|Unclassified AMINO ACID METABOLISM|CARBOHYDRATE METABOLISMPropanoate metabolism|Pyruvate metabolism|TaurCARBOHYDRATE METABOLISM|METABOLISM OF OTHER AMINO ACIDSArginine and proline metabolism AMINO ACID METABOLISMPropanoate metabolism CARBOHYDRATE METABOLISMArginine and proline metabolism|Nitrogen metabol AMINO ACID METABOLISM|ENERGY METABOLISM|NUCLEOTIDE METABOLISMCarbon fixation in photosynthetic organisms|Glycol CARBOHYDRATE METABOLISM|ENERGY METABOLISMCysteine and methionine metabolism|Glycine, serin AMINO ACID METABOLISMButanoate metabolism CARBOHYDRATE METABOLISMArginine and proline metabolism AMINO ACID METABOLISMUnclassified OTHERSArginine and proline metabolism AMINO ACID METABOLISMArginine and proline metabolism AMINO ACID METABOLISMPhosphotransferase system (PTS)|Transporters|UnclMEMBRANE TRANSPORT|OTHERSUnclassified OTHERS|SIGNAL TRANSDUCTION MECHANISMSOxidative phosphorylation|RNA degradation ENERGY METABOLISM|FOLDING, SORTING AND DEGRADATIONPyrimidine metabolism NUCLEOTIDE METABOLISMThiamine metabolism METABOLISM OF COFACTORS AND VITAMINSPeroxisome|Terpenoid backbone biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITES|TRANSPORT AND CATABOLISMUnclassified OTHERSPyrimidine metabolism NUCLEOTIDE METABOLISMPentose phosphate pathway CARBOHYDRATE METABOLISMUnclassified OTHERS

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Purine metabolism NUCLEOTIDE METABOLISMPurine metabolism|Pyrimidine metabolism NUCLEOTIDE METABOLISMThiamine metabolism METABOLISM OF COFACTORS AND VITAMINSPurine metabolism NUCLEOTIDE METABOLISMPyrimidine metabolism NUCLEOTIDE METABOLISMPentose phosphate pathway|Purine metabolism CARBOHYDRATE METABOLISM|NUCLEOTIDE METABOLISMThiamine metabolism METABOLISM OF COFACTORS AND VITAMINSFolate biosynthesis METABOLISM OF COFACTORS AND VITAMINSPurine metabolism NUCLEOTIDE METABOLISMBiosynthesis of siderophore group nonribosomal pe BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|CARBOHYDRATE METABOLISM|FOLDING, SORTING AND DEGRADATION|GLYCAN BIOSYNTHESIS AND METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISM|OTHERS|REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINS|UNPROCESSEDNicotinate and nicotinamide metabolism METABOLISM OF COFACTORS AND VITAMINSAmino sugar and nucleotide sugar metabolism|GalaCARBOHYDRATE METABOLISMAmino sugar and nucleotide sugar metabolism|GalaCARBOHYDRATE METABOLISMAmino sugar and nucleotide sugar metabolism|Fru CARBOHYDRATE METABOLISMGlycerophospholipid metabolism|Phosphonate and LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDSGlycerophospholipid metabolism|Phosphonate and LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDSNicotinate and nicotinamide metabolism METABOLISM OF COFACTORS AND VITAMINSChromosome|RNA degradation FOLDING, SORTING AND DEGRADATION|REPLICATION AND REPAIRRiboflavin metabolism METABOLISM OF COFACTORS AND VITAMINSAmino sugar and nucleotide sugar metabolism|Fru CARBOHYDRATE METABOLISMAmino sugar and nucleotide sugar metabolism CARBOHYDRATE METABOLISMPolyketide sugar unit biosynthesis|Streptomycin bioBIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|BIOSYNTHESIS OF SECONDARY METABOLITESAmino sugar and nucleotide sugar metabolism|Star CARBOHYDRATE METABOLISMPantothenate and CoA biosynthesis METABOLISM OF COFACTORS AND VITAMINSAmino sugar and nucleotide sugar metabolism|Star CARBOHYDRATE METABOLISMLipopolysaccharide biosynthesis|LipopolysaccharideGLYCAN BIOSYNTHESIS AND METABOLISMGlycerophospholipid metabolism LIPID METABOLISMPurine metabolism|Selenoamino acid metabolism|SENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDS|NUCLEOTIDE METABOLISMGlycerophospholipid metabolism|PhosphatidylinositLIPID METABOLISM|SIGNAL TRANSDUCTIONUnclassified PROTEIN FOLDING AND ASSOCIATED PROCESSINGAmino sugar and nucleotide sugar metabolism CARBOHYDRATE METABOLISMChromosome|Purine metabolism NUCLEOTIDE METABOLISM|REPLICATION AND REPAIRDNA replication proteins|Unclassified REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINSUnclassified OTHERSPurine metabolism NUCLEOTIDE METABOLISMUnclassified TRANSLATION PROTEINSBiosynthesis of siderophore group nonribosomal pe BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDESTwo-component system SIGNAL TRANSDUCTIONCytosolic DNA-sensing pathway|DNA repair and re IMMUNE SYSTEM|NEURODEGENERATIVE DISEASES|NUCLEOTIDE METABOLISM|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|TRANSCRIPTION|TRANSCRIPTION RELATED PROTEINS|UNPROCESSEDTerpenoid backbone biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITESTwo-component system SIGNAL TRANSDUCTIONPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSLipoic acid metabolism METABOLISM OF COFACTORS AND VITAMINSTwo-component system|Unclassified NUCLEOTIDE METABOLISM|SIGNAL TRANSDUCTIONBase excision repair|Chromosome|DNA repair and rFOLDING, SORTING AND DEGRADATION|NUCLEOTIDE METABOLISM|REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINS|UNPROCESSEDPurine metabolism|Pyrimidine metabolism|RNA degFOLDING, SORTING AND DEGRADATION|NUCLEOTIDE METABOLISM

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Amino sugar and nucleotide sugar metabolism|GalaCARBOHYDRATE METABOLISMAmino sugar and nucleotide sugar metabolism|Glyc BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDSGlycerophospholipid metabolism|Inositol phosphateCARBOHYDRATE METABOLISM|LIPID METABOLISM|SIGNAL TRANSDUCTIONUnclassified MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULESPeptidoglycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISMGlycosyltransferases|N-Glycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISMLysosome TRANSPORT AND CATABOLISMGlycerolipid metabolism LIPID METABOLISMTwo-component system SIGNAL TRANSDUCTIONPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSGlycerophospholipid metabolism LIPID METABOLISMLipopolysaccharide biosynthesis proteins GLYCAN BIOSYNTHESIS AND METABOLISMPantothenate and CoA biosynthesis METABOLISM OF COFACTORS AND VITAMINSGlycerophospholipid metabolism|Glycine, serine a AMINO ACID METABOLISM|LIPID METABOLISMCarbon fixation in photosynthetic organisms|Pyruv CARBOHYDRATE METABOLISM|ENERGY METABOLISMPyruvate metabolism|Reductive carboxylate cycle (CCARBOHYDRATE METABOLISM|ENERGY METABOLISMSelenoamino acid metabolism METABOLISM OF OTHER AMINO ACIDSUbiquitin system|Unclassified FOLDING, SORTING AND DEGRADATION|INORGANIC ION TRANSPORT AND METABOLISM|OTHERS|PROTEIN FOLDING AND ASSOCIATED PROCESSINGUnclassified INORGANIC ION TRANSPORT AND METABOLISMCysteine and methionine metabolism AMINO ACID METABOLISMBiotin metabolism METABOLISM OF COFACTORS AND VITAMINSSelenoamino acid metabolism|Thiamine metabolis METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDSLipoic acid metabolism METABOLISM OF COFACTORS AND VITAMINSGlucosinolate biosynthesis|Glycosaminoglycan biosyAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|GLYCAN BIOSYNTHESIS AND METABOLISM|OTHERSUnclassified OTHERSGlycosaminoglycan biosynthesis - keratan sulfate|GlGLYCAN BIOSYNTHESIS AND METABOLISMUnclassified OTHERSGlycosaminoglycan biosynthesis - chondroitin sulfa ENERGY METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM1- and 2-Methylnaphthalene degradation|Geraniol dOTHERS|XENOBIOTICS BIODEGRADATION AND METABOLISMPropanoate metabolism|Pyruvate metabolism|Styr CARBOHYDRATE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMButanoate metabolism|Styrene degradation CARBOHYDRATE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMUnclassified ENERGY METABOLISMButanoate metabolism|Synthesis and degradation ofAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|LIPID METABOLISMBenzoate degradation via hydroxylation XENOBIOTICS BIODEGRADATION AND METABOLISMBenzoate degradation via CoA ligation|Butanoate CARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTION|XENOBIOTICS BIODEGRADATION AND METABOLISMUnclassified OTHERSFolate biosynthesis METABOLISM OF COFACTORS AND VITAMINSUnclassified GENERAL FUNCTION PREDICTION ONLYAminoacyl-tRNA biosynthesis|Selenoamino acid me METABOLISM OF OTHER AMINO ACIDS|TRANSLATIONTranscription factors TRANSCRIPTIONApoptosis|Base excision repair|DNA repair and rec BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITES|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|CELL GROWTH AND DEATH|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|GLYCAN BIOSYNTHESIS AND METABOLISM|IMMUNE SYSTEM|OTHERS|REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINSBase excision repair|DNA repair and recombination FOLDING, SORTING AND DEGRADATION|GENERAL FUNCTION PREDICTION ONLY|GLYCAN BIOSYNTHESIS AND METABOLISM|IMMUNE SYSTEM DISEASES|OTHERS|REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINS|SPORULATION|TRANSCRIPTION RELATED PROTEINS|TRANSLATION PROTEINS2,4-Dichlorobenzoate degradation|Ascorbate and alBIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|CELL DIVISION|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|XENOBIOTICS BIODEGRADATION AND METABOLISMDrug metabolism - other enzymes|Tropane, piperidinBIOSYNTHESIS OF SECONDARY METABOLITES|OTHERS|XENOBIOTICS BIODEGRADATION AND METABOLISMPentose and glucuronate interconversions|Starch a CARBOHYDRATE METABOLISMAscorbate and aldarate metabolism|Caprolactam d CARBOHYDRATE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

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Bisphenol A degradation XENOBIOTICS BIODEGRADATION AND METABOLISMUnclassified OTHERSGlycerolipid metabolism LIPID METABOLISMBenzoate degradation via hydroxylation XENOBIOTICS BIODEGRADATION AND METABOLISMUnclassified TRANSLATION PROTEINSGlycerolipid metabolism|Steroid biosynthesis LIPID METABOLISMPentose phosphate pathway CARBOHYDRATE METABOLISMGlycerophospholipid metabolism|alpha-Linolenic a LIPID METABOLISMAlzheimer's disease|Glycerolipid metabolism|PPAR ENDOCRINE SYSTEM|LIPID METABOLISM|NEURODEGENERATIVE DISEASESArachidonic acid metabolism|Ether lipid metabolis CIRCULATORY SYSTEM|ENDOCRINE SYSTEM|IMMUNE SYSTEM|LIPID METABOLISM|NERVOUS SYSTEM|SIGNAL TRANSDUCTIONPenicillin and cephalosporin biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITES1,4-Dichlorobenzene degradation|Fluorobenzoate XENOBIOTICS BIODEGRADATION AND METABOLISMEther lipid metabolism|Unclassified LIPID METABOLISMBiosynthesis of unsaturated fatty acids|Glycan bin LIPID METABOLISM|SIGNALING MOLECULES AND INTERACTION|TRANSPORT AND CATABOLISMUnclassified OTHERSUnclassified OTHERSBacterial chemotaxis|Bacterial motility proteins| CELL MOTILITY|OTHERS|SIGNAL TRANSDUCTIONGlycerophospholipid metabolism LIPID METABOLISMUnclassified OTHERSUnclassified OTHERSButanoate metabolism CARBOHYDRATE METABOLISMInsulin signaling pathway ENDOCRINE SYSTEMUnclassified OTHERSUnclassified LIPID METABOLISMDNA repair and recombination proteins|Mismatch reREPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINSDNA repair and recombination proteins|Mismatch r REPLICATION AND REPAIRBase excision repair|Cell cycle - yeast|Cytosolic CELL GROWTH AND DEATH|IMMUNE SYSTEM|REPLICATION AND REPAIRUnclassified REPLICATION, RECOMBINATION AND REPAIR PROTEINSDNA repair and recombination proteins|HomologousREPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINSDNA repair and recombination proteins|Mismatch reREPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINSRNA degradation|Unclassified FOLDING, SORTING AND DEGRADATION|OTHERS|REPLICATION, RECOMBINATION AND REPAIR PROTEINSUnclassified TRANSLATION PROTEINSRNA degradation|Unclassified FOLDING, SORTING AND DEGRADATION|TRANSLATION PROTEINSUnclassified TRANSLATION PROTEINSBenzoate degradation via CoA ligation|Biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITES|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISMPyruvate metabolism CARBOHYDRATE METABOLISMMethane metabolism ENERGY METABOLISMFatty acid biosynthesis|Lipid biosynthesis proteins LIPID METABOLISMChromosome|Endocytosis|Peptidases|RIG-I-like recENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|REPLICATION AND REPAIR|TRANSPORT AND CATABOLISMBiosynthesis of unsaturated fatty acids|Lipid bios LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|TRANSPORT AND CATABOLISMUnclassified OTHERSFatty acid elongation in mitochondria|Lipid biosynt LIPID METABOLISM|TRANSPORT AND CATABOLISMPropanoate metabolism|Valine, leucine and isoleuc AMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|METABOLISM OF OTHER AMINO ACIDSPyruvate metabolism CARBOHYDRATE METABOLISMUnclassified REPLICATION, RECOMBINATION AND REPAIR PROTEINSUnclassified REPLICATION, RECOMBINATION AND REPAIR PROTEINS

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Base excision repair|DNA repair and recombination REPLICATION AND REPAIRUnclassified RESTRICTION ENZYMEUnclassified RESTRICTION ENZYMEUnclassified RESTRICTION ENZYMEDNA repair and recombination proteins REPLICATION AND REPAIRDNA repair and recombination proteins|HomologouREPLICATION AND REPAIRLysosome TRANSPORT AND CATABOLISMDNA repair and recombination proteins|HomologouREPLICATION AND REPAIRDNA repair and recombination proteins REPLICATION AND REPAIRChromosome|Unclassified REPLICATION AND REPAIR|TRANSLATION PROTEINSUnclassified TRANSLATION PROTEINSRNA degradation FOLDING, SORTING AND DEGRADATIONUnclassified TRANSLATION PROTEINSDNA replication|DNA replication proteins REPLICATION AND REPAIRUnclassified TRANSLATION PROTEINSUnclassified REPLICATION, RECOMBINATION AND REPAIR PROTEINSAsthma|Spliceosome|Unclassified IMMUNE SYSTEM DISEASES|OTHERS|TRANSCRIPTIONUnclassified TRANSLATION PROTEINSUnclassified TRANSLATION PROTEINSUnclassified TRANSLATION PROTEINSAscorbate and aldarate metabolism|Butirosin and n BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENERGY METABOLISM|ENZYME FAMILIES|GLYCAN BIOSYNTHESIS AND METABOLISM|INFECTIOUS DISEASES|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMSFolate biosynthesis|Two-component system|gammaMETABOLISM OF COFACTORS AND VITAMINS|SIGNAL TRANSDUCTION|XENOBIOTICS BIODEGRADATION AND METABOLISMGlycolysis / Gluconeogenesis CARBOHYDRATE METABOLISMCarbon fixation in photosynthetic organisms|Fruct CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|ENERGY METABOLISMStarch and sucrose metabolism CARBOHYDRATE METABOLISMHistidine metabolism AMINO ACID METABOLISMAlzheimer's disease|Amyotrophic lateral sclerosis CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY SYSTEM|DEVELOPMENT|ENDOCRINE SYSTEM|IMMUNE SYSTEM|MEMBRANE TRANSPORT|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|OTHERS|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|SPORULATION|TRANSCRIPTIONGlyoxylate and dicarboxylate metabolism CARBOHYDRATE METABOLISMRiboflavin metabolism|Two-component system|gamMETABOLISM OF COFACTORS AND VITAMINS|SIGNAL TRANSDUCTION|XENOBIOTICS BIODEGRADATION AND METABOLISMUnclassified OTHERSInositol phosphate metabolism|PhosphatidylinositolBIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTIONInositol phosphate metabolism|Riboflavin metabo CARBOHYDRATE METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISMGlycerophospholipid metabolism LIPID METABOLISMGlycine, serine and threonine metabolism|Unclassif AMINO ACID METABOLISM|SIGNAL TRANSDUCTION MECHANISMSInositol phosphate metabolism|PhosphatidylinositolCARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTIONCarbon fixation in photosynthetic organisms|Fruc CARBOHYDRATE METABOLISM|ENERGY METABOLISMEther lipid metabolism|Fc gamma R-mediated phagoIMMUNE SYSTEM|LIPID METABOLISMgamma-Hexachlorocyclohexane degradation XENOBIOTICS BIODEGRADATION AND METABOLISMLipopolysaccharide biosynthesis|LipopolysaccharideGLYCAN BIOSYNTHESIS AND METABOLISMFructose and mannose metabolism CARBOHYDRATE METABOLISMAdherens junction|Adipocytokine signaling pathway|CANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|ENDOCRINE SYSTEM|GLYCAN BIOSYNTHESIS AND METABOLISM|IMMUNE SYSTEM|IMMUNE SYSTEM DISEASES|INFECTIOUS DISEASES|METABOLIC DISEASES|NERVOUS SYSTEM|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMS|SIGNALING MOLECULES AND INTERACTIONCellular antigens|Nicotinate and nicotinamide me METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISM|SIGNALING MOLECULES AND INTERACTIONInositol phosphate metabolism|PhosphatidylinositolCARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTIONInositol phosphate metabolism|PhosphatidylinositolCARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTIONPurine metabolism|Pyrimidine metabolism NUCLEOTIDE METABOLISMInositol phosphate metabolism CARBOHYDRATE METABOLISM

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Unclassified OTHERSSulfur metabolism ENERGY METABOLISMFructose and mannose metabolism CARBOHYDRATE METABOLISMUnclassified METABOLISM OF COFACTORS AND VITAMINSPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSCysteine and methionine metabolism AMINO ACID METABOLISMUnclassified CARBOHYDRATE METABOLISMInositol phosphate metabolism CARBOHYDRATE METABOLISMAdipocytokine signaling pathway|Galactose metabolCARBOHYDRATE METABOLISM|ENDOCRINE SYSTEMApoptosis CELL GROWTH AND DEATHUnclassified REPLICATION, RECOMBINATION AND REPAIR PROTEINSDNA repair and recombination proteins|Ether lipid LIPID METABOLISM|OTHERS|REPLICATION AND REPAIR|TRANSCRIPTIONUnclassified INORGANIC ION TRANSPORT AND METABOLISMAlzheimer's disease|Calcium signaling pathway|ChemCANCERS|CARBOHYDRATE METABOLISM|CELL COMMUNICATION|CIRCULATORY SYSTEM|ENDOCRINE SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|SIGNAL TRANSDUCTIONLysosome|Sphingolipid metabolism LIPID METABOLISM|TRANSPORT AND CATABOLISMPantothenate and CoA biosynthesis METABOLISM OF COFACTORS AND VITAMINSPurine metabolism|Pyrimidine metabolism NUCLEOTIDE METABOLISMInsulin signaling pathway|Progesterone-mediated ENDOCRINE SYSTEM|NUCLEOTIDE METABOLISMBacterial toxins|Ether lipid metabolism|Glyceroph CARBOHYDRATE METABOLISM|LIPID METABOLISM|SIGNALING MOLECULES AND INTERACTIONPurine metabolism NUCLEOTIDE METABOLISMUnclassified NUCLEOTIDE METABOLISMEndocytosis|Ether lipid metabolism|Fc gamma R-m ENDOCRINE SYSTEM|IMMUNE SYSTEM|LIPID METABOLISM|TRANSPORT AND CATABOLISMLysosome TRANSPORT AND CATABOLISMGlycerophospholipid metabolism LIPID METABOLISMUnclassified NUCLEOTIDE METABOLISMUnclassified NUCLEOTIDE METABOLISMPurine metabolism NUCLEOTIDE METABOLISMLysosome|Unclassified INORGANIC ION TRANSPORT AND METABOLISM|TRANSPORT AND CATABOLISMSphingolipid metabolism|Steroid hormone biosynth LIPID METABOLISMGlycosaminoglycan degradation|Lysosome GLYCAN BIOSYNTHESIS AND METABOLISM|TRANSPORT AND CATABOLISMGlycosaminoglycan degradation|Lysosome GLYCAN BIOSYNTHESIS AND METABOLISM|TRANSPORT AND CATABOLISMGlycosaminoglycan degradation|Lysosome GLYCAN BIOSYNTHESIS AND METABOLISM|TRANSPORT AND CATABOLISMGlycosaminoglycan degradation|Lysosome GLYCAN BIOSYNTHESIS AND METABOLISM|TRANSPORT AND CATABOLISMUnclassified INORGANIC ION TRANSPORT AND METABOLISMLysosome|Sphingolipid metabolism LIPID METABOLISM|TRANSPORT AND CATABOLISMPurine metabolism NUCLEOTIDE METABOLISMgamma-Hexachlorocyclohexane degradation XENOBIOTICS BIODEGRADATION AND METABOLISMPhosphonate and phosphinate metabolism METABOLISM OF OTHER AMINO ACIDSPhosphonate and phosphinate metabolism METABOLISM OF OTHER AMINO ACIDSPeptidases|Unclassified ENZYME FAMILIES|NUCLEOTIDE METABOLISM|PROTEIN FOLDING AND ASSOCIATED PROCESSINGGlycosaminoglycan degradation|Unclassified CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|OTHERSStarch and sucrose metabolism CARBOHYDRATE METABOLISMStarch and sucrose metabolism CARBOHYDRATE METABOLISMUnclassified OTHERSN-Glycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISMUnclassified OTHERS

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High-mannose type N-glycan biosynthesis|N-Glycan GLYCAN BIOSYNTHESIS AND METABOLISMN-Glycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISMStarch and sucrose metabolism CARBOHYDRATE METABOLISMUnclassified OTHERSUnclassified CARBOHYDRATE METABOLISMUnclassified CARBOHYDRATE METABOLISMAmino sugar and nucleotide sugar metabolism CARBOHYDRATE METABOLISMUnclassified CARBOHYDRATE METABOLISMUnclassified PROTEIN FOLDING AND ASSOCIATED PROCESSINGPentose and glucuronate interconversions|Starch a CARBOHYDRATE METABOLISMAmino sugar and nucleotide sugar metabolism|Two CARBOHYDRATE METABOLISM|OTHERS|SIGNAL TRANSDUCTIONBacterial toxins|Lysosome|Other glycan degradatio GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|SIGNALING MOLECULES AND INTERACTION|TRANSPORT AND CATABOLISMGalactose metabolism|Lysosome|Starch and sucros CARBOHYDRATE METABOLISM|TRANSPORT AND CATABOLISMCyanoamino acid metabolism|Phenylpropanoid biosBIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|METABOLISM OF OTHER AMINO ACIDSGalactose metabolism|Glycerolipid metabolism|GlycCARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|TRANSPORT AND CATABOLISMGalactose metabolism|Glycosaminoglycan degradatioCARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|TRANSPORT AND CATABOLISMLysosome|Other glycan degradation GLYCAN BIOSYNTHESIS AND METABOLISM|TRANSPORT AND CATABOLISMLysosome|Other glycan degradation GLYCAN BIOSYNTHESIS AND METABOLISM|TRANSPORT AND CATABOLISMGalactose metabolism|Starch and sucrose metabol CARBOHYDRATE METABOLISMStarch and sucrose metabolism CARBOHYDRATE METABOLISMGalactose metabolism|Starch and sucrose metabol CARBOHYDRATE METABOLISMDrug metabolism - other enzymes|Flavone and flav BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMStarch and sucrose metabolism CARBOHYDRATE METABOLISMBacterial toxins|Glycosaminoglycan degradation GLYCAN BIOSYNTHESIS AND METABOLISM|SIGNALING MOLECULES AND INTERACTIONAmino sugar and nucleotide sugar metabolism|Star CARBOHYDRATE METABOLISMStarch and sucrose metabolism CARBOHYDRATE METABOLISMStarch and sucrose metabolism CARBOHYDRATE METABOLISMUnclassified OTHERSUnclassified CARBOHYDRATE METABOLISMLysosome|Other glycan degradation|Sphingolipid GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|TRANSPORT AND CATABOLISMLysosome|Sphingolipid metabolism LIPID METABOLISM|TRANSPORT AND CATABOLISMGlycosaminoglycan degradation|Lysosome GLYCAN BIOSYNTHESIS AND METABOLISM|TRANSPORT AND CATABOLISMOther glycan degradation GLYCAN BIOSYNTHESIS AND METABOLISMAmino sugar and nucleotide sugar metabolism|ChaperCARBOHYDRATE METABOLISM|FOLDING, SORTING AND DEGRADATION|GLYCAN BIOSYNTHESIS AND METABOLISM|TRANSPORT AND CATABOLISMStarch and sucrose metabolism CARBOHYDRATE METABOLISMAmino sugar and nucleotide sugar metabolism CARBOHYDRATE METABOLISMStarch and sucrose metabolism CARBOHYDRATE METABOLISMUnclassified OTHERSStarch and sucrose metabolism CARBOHYDRATE METABOLISMPentose and glucuronate interconversions|Starch a CARBOHYDRATE METABOLISMUnclassified OTHERSUnclassified CARBOHYDRATE METABOLISMUnclassified CARBOHYDRATE METABOLISMGlycosaminoglycan degradation|Lysosome GLYCAN BIOSYNTHESIS AND METABOLISM|TRANSPORT AND CATABOLISMFructose and mannose metabolism CARBOHYDRATE METABOLISMUnclassified CARBOHYDRATE METABOLISM

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Fructose and mannose metabolism CARBOHYDRATE METABOLISMUnclassified OTHERSN-Glycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISMGalactose metabolism CARBOHYDRATE METABOLISMGlycolysis / Gluconeogenesis CARBOHYDRATE METABOLISMUnclassified OTHERSStarch and sucrose metabolism CARBOHYDRATE METABOLISMStarch and sucrose metabolism CARBOHYDRATE METABOLISMOther glycan degradation GLYCAN BIOSYNTHESIS AND METABOLISMUnclassified CARBOHYDRATE METABOLISMBase excision repair|Chromosome|DNA repair and rIMMUNE SYSTEM DISEASES|REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINSNicotinate and nicotinamide metabolism|Purine meMETABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISMBase excision repair|DNA repair and recombination REPLICATION AND REPAIRBase excision repair|DNA repair and recombination REPLICATION AND REPAIR|TRANSCRIPTIONBase excision repair|DNA repair and recombination REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINSPurine metabolism NUCLEOTIDE METABOLISMCAM ligands|Calcium signaling pathway|Cellular an METABOLISM OF COFACTORS AND VITAMINS|SIGNAL TRANSDUCTION|SIGNALING MOLECULES AND INTERACTIONPurine metabolism|Pyrimidine metabolism NUCLEOTIDE METABOLISMCysteine and methionine metabolism AMINO ACID METABOLISMCysteine and methionine metabolism|Selenoamino AMINO ACID METABOLISM|METABOLISM OF OTHER AMINO ACIDSBiosynthesis of siderophore group nonribosomal pe BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDESArachidonic acid metabolism|Peroxisome|Tetrachl LIPID METABOLISM|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMArachidonic acid metabolism|Peptidases ENZYME FAMILIES|LIPID METABOLISMBiotin metabolism|Epithelial cell signaling in Heli AMINO ACID METABOLISM|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|GLYCAN BIOSYNTHESIS AND METABOLISM|INFECTIOUS DISEASES|MEMBRANE TRANSPORT|METABOLISM OF COFACTORS AND VITAMINS|PROTEIN FOLDING AND ASSOCIATED PROCESSINGPeptidases|Unclassified AMINO ACID METABOLISM|ENZYME FAMILIESArginine and proline metabolism|Glutathione meta AMINO ACID METABOLISM|ENZYME FAMILIES|METABOLISM OF OTHER AMINO ACIDSPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESCellular antigens|Glutathione metabolism|HematopoENDOCRINE SYSTEM|ENZYME FAMILIES|IMMUNE SYSTEM|METABOLISM OF OTHER AMINO ACIDS|SIGNALING MOLECULES AND INTERACTIONPeptidases ENZYME FAMILIESGlutathione metabolism|Peptidases ENZYME FAMILIES|METABOLISM OF OTHER AMINO ACIDSPeptidases ENZYME FAMILIESArginine and proline metabolism|Glutathione meta AMINO ACID METABOLISM|ENZYME FAMILIES|METABOLISM OF OTHER AMINO ACIDSCellular antigens|Peptidases|Renin-angiotensin sys ENDOCRINE SYSTEM|ENZYME FAMILIES|SIGNALING MOLECULES AND INTERACTIONPeptidases ENZYME FAMILIESPeptidases|Unclassified ENZYME FAMILIES|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESArginine and proline metabolism|Glutathione meta AMINO ACID METABOLISM|ENZYME FAMILIES|METABOLISM OF OTHER AMINO ACIDSPeptidases ENZYME FAMILIESPeptidases|Unclassified AMINO ACID METABOLISM|ENZYME FAMILIESChaperones and folding catalysts|Lysosome|Peptid ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|TRANSPORT AND CATABOLISMChaperones and folding catalysts|Peptidases ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATIONPeptidases ENZYME FAMILIES

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Peptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESCellular antigens|Peptidases ENZYME FAMILIES|SIGNALING MOLECULES AND INTERACTIONChaperones and folding catalysts|Lysosome|Peptid ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|TRANSPORT AND CATABOLISMCellular antigens|Hypertrophic cardiomyopathy (H CIRCULATORY DISEASES|ENDOCRINE SYSTEM|ENZYME FAMILIES|SIGNALING MOLECULES AND INTERACTIONPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases|Unclassified AMINO ACID METABOLISM|ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases|Peptidoglycan biosynthesis|UnclassifiedENZYME FAMILIES|GLYCAN BIOSYNTHESIS AND METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULESChaperones and folding catalysts|Lysosome|Peptid ENDOCRINE SYSTEM|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|TRANSPORT AND CATABOLISMPeptidases ENZYME FAMILIESPeptidases|Renin-angiotensin system|Unclassified AMINO ACID METABOLISM|ENDOCRINE SYSTEM|ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESParkinson's disease|Peptidases|Ubiquitin system ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|NEURODEGENERATIVE DISEASESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESCAM ligands|Chaperones and folding catalysts|ComAMINO ACID METABOLISM|CELL COMMUNICATION|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|MEMBRANE TRANSPORT|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|SIGNALING MOLECULES AND INTERACTIONPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESComplement and coagulation cascades|Peptidases ENZYME FAMILIES|IMMUNE SYSTEMPeptidases ENZYME FAMILIESChaperones and folding catalysts|Peptidases|Two ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|SIGNAL TRANSDUCTIONPeptidases|Sporulation CELLULAR PROCESSES AND SIGNALING|ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESComplement and coagulation cascades|Peptidases ENZYME FAMILIES|IMMUNE SYSTEMPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESCAM ligands|Complement and coagulation cascadesENZYME FAMILIES|IMMUNE SYSTEM|SIGNALING MOLECULES AND INTERACTIONChaperones and folding catalysts|Peptidases ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATIONComplement and coagulation cascades|Peptidases ENZYME FAMILIES|IMMUNE SYSTEMPeptidases|Secretion system ENZYME FAMILIES|MEMBRANE TRANSPORTChaperones and folding catalysts|Peptidases ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION

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Peptidases ENZYME FAMILIESDNA repair and recombination proteins|Peptidases ENZYME FAMILIES|REPLICATION AND REPAIRPeptidases|Protein export ENZYME FAMILIES|MEMBRANE TRANSPORTPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESChaperones and folding catalysts|Peptidases ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATIONAlzheimer's disease|Amyotrophic lateral sclerosis CELL GROWTH AND DEATH|ENVIRONMENTAL ADAPTATION|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|INFECTIOUS DISEASES|MEMBRANE TRANSPORT|NEURODEGENERATIVE DISEASES|OTHERS|SIGNAL TRANSDUCTION|TRANSPORT AND CATABOLISMAntigen processing and presentation|Chaperones anENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|TRANSPORT AND CATABOLISMPeptidases ENZYME FAMILIESAntigen processing and presentation|Chaperones anENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|TRANSPORT AND CATABOLISMAntigen processing and presentation|Lysosome|PepENZYME FAMILIES|IMMUNE SYSTEM|TRANSPORT AND CATABOLISMAmyotrophic lateral sclerosis (ALS)|Cytosolic DNA- ENZYME FAMILIES|IMMUNE SYSTEM|NEURODEGENERATIVE DISEASESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESCell cycle|Cell cycle - yeast|Chromosome|Meiosis - CELL GROWTH AND DEATH|ENZYME FAMILIES|REPLICATION AND REPAIRPeptidases ENZYME FAMILIESBacterial toxins|Peptidases ENZYME FAMILIES|SIGNALING MOLECULES AND INTERACTIONAlzheimer's disease|Lysosome|Neurotrophin signal CELLULAR PROCESSES AND SIGNALING|ENZYME FAMILIES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|OTHERS|SIGNAL TRANSDUCTION|TRANSPORT AND CATABOLISMPeptidases ENZYME FAMILIESPeptidases|Protein export ENZYME FAMILIES|MEMBRANE TRANSPORTPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESChaperones and folding catalysts|Peptidases ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATIONBacterial motility proteins|Bacterial secretion sys CELL MOTILITY|ENZYME FAMILIES|MEMBRANE TRANSPORT|OTHERSAlzheimer's disease|Peptidases ENZYME FAMILIES|NEURODEGENERATIVE DISEASESPeptidases ENZYME FAMILIESLysosome|Peptidases ENZYME FAMILIES|TRANSPORT AND CATABOLISMCAM ligands|Cellular antigens|Chaperones and foldiCELLULAR PROCESSES AND SIGNALING|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|OTHERS|SIGNALING MOLECULES AND INTERACTIONAlzheimer's disease|Cellular antigens|HematopoietiENDOCRINE SYSTEM|ENZYME FAMILIES|IMMUNE SYSTEM|NEURODEGENERATIVE DISEASES|SIGNALING MOLECULES AND INTERACTIONPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases|Renin-angiotensin system ENDOCRINE SYSTEM|ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases|Vibrio cholerae infection|Vibrio cholera ENZYME FAMILIES|INFECTIOUS DISEASESPeptidases ENZYME FAMILIESBacterial toxins|Peptidases ENZYME FAMILIES|SIGNALING MOLECULES AND INTERACTIONPeptidases ENZYME FAMILIESLeishmania infection|Peptidases ENZYME FAMILIES|INFECTIOUS DISEASESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESAlzheimer's disease|Peptidases ENZYME FAMILIES|NEURODEGENERATIVE DISEASESPeptidases ENZYME FAMILIES

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Peptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESBacterial toxins|Peptidases ENZYME FAMILIES|SIGNALING MOLECULES AND INTERACTIONPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESGermination|Peptidases CELLULAR PROCESSES AND SIGNALING|ENZYME FAMILIESPeptidases ENZYME FAMILIESAlzheimer's disease|Cellular antigens|Epithelial cell ENZYME FAMILIES|INFECTIOUS DISEASES|NEURODEGENERATIVE DISEASES|SIGNALING MOLECULES AND INTERACTIONPeptidases ENZYME FAMILIESPeptidases ENZYME FAMILIESPeptidases|Proteasome|Ubiquitin system ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATIONPeptidases|Peptidoglycan biosynthesis|Protein expoENZYME FAMILIES|GLYCAN BIOSYNTHESIS AND METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|MEMBRANE TRANSPORTLipopolysaccharide biosynthesis proteins|Spliceoso CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|OTHERS|TRANSCRIPTIONAmino sugar and nucleotide sugar metabolism|ButirAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDS|REPLICATION AND REPAIRAlanine, aspartate and glutamate metabolism|Cyan AMINO ACID METABOLISM|ENERGY METABOLISM|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDSGlyoxylate and dicarboxylate metabolism|One carboCARBOHYDRATE METABOLISM|METABOLISM OF COFACTORS AND VITAMINSPenicillin and cephalosporin biosynthesis|Peptidase BIOSYNTHESIS OF SECONDARY METABOLITES|ENZYME FAMILIESArginine and proline metabolism AMINO ACID METABOLISMAlanine, aspartate and glutamate metabolism|Histi AMINO ACID METABOLISMArginine and proline metabolism AMINO ACID METABOLISMLysine biosynthesis AMINO ACID METABOLISMNicotinate and nicotinamide metabolism METABOLISM OF COFACTORS AND VITAMINSAlanine, aspartate and glutamate metabolism|Argi AMINO ACID METABOLISM|ENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDSLysosome|Sphingolipid metabolism LIPID METABOLISM|TRANSPORT AND CATABOLISMPrimary bile acid biosynthesis|Secondary bile acid b LIPID METABOLISMAmino sugar and nucleotide sugar metabolism|GalaCARBOHYDRATE METABOLISMLysosome|Other glycan degradation GLYCAN BIOSYNTHESIS AND METABOLISM|TRANSPORT AND CATABOLISMChromosome|Unclassified MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|REPLICATION AND REPAIRPhenylalanine metabolism AMINO ACID METABOLISMArginine and proline metabolism|Benzoate degrada AMINO ACID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|XENOBIOTICS BIODEGRADATION AND METABOLISMAmino sugar and nucleotide sugar metabolism CARBOHYDRATE METABOLISMBacterial chemotaxis|Bacterial motility proteins CELL MOTILITYUnclassified OTHERSLysine biosynthesis AMINO ACID METABOLISMGlyoxylate and dicarboxylate metabolism|Nitrogen CARBOHYDRATE METABOLISM|ENERGY METABOLISMArginine and proline metabolism|Atrazine degradatioAMINO ACID METABOLISM|INFECTIOUS DISEASES|NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMUnclassified OTHERSArginine and proline metabolism AMINO ACID METABOLISMArginine and proline metabolism|Atrazine degradat AMINO ACID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMUnclassified OTHERSUnclassified OTHERSGlutathione metabolism METABOLISM OF OTHER AMINO ACIDSUnclassified OTHERSUnclassified OTHERS

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Unclassified OTHERSUnclassified OTHERSGlycosylphosphatidylinositol(GPI)-anchor biosynthesGLYCAN BIOSYNTHESIS AND METABOLISMPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSArginine and proline metabolism|Peptidases AMINO ACID METABOLISM|ENZYME FAMILIESArginine and proline metabolism AMINO ACID METABOLISMCell cycle|Chromosome|Chronic myeloid leukemia|HCANCERS|CELL GROWTH AND DEATH|NEURODEGENERATIVE DISEASES|REPLICATION AND REPAIR|SIGNAL TRANSDUCTIONArginine and proline metabolism AMINO ACID METABOLISMArginine and proline metabolism AMINO ACID METABOLISMPurine metabolism NUCLEOTIDE METABOLISMDrug metabolism - other enzymes|Pantothenate an METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDS|NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMAlanine, aspartate and glutamate metabolism|Pept AMINO ACID METABOLISM|ENZYME FAMILIES|NUCLEOTIDE METABOLISMPurine metabolism NUCLEOTIDE METABOLISMPenicillin and cephalosporin biosynthesis|Two-com BIOSYNTHESIS OF SECONDARY METABOLITES|SIGNAL TRANSDUCTIONHistidine metabolism AMINO ACID METABOLISMGlutathione metabolism METABOLISM OF OTHER AMINO ACIDSArginine and proline metabolism AMINO ACID METABOLISMArginine and proline metabolism AMINO ACID METABOLISMArginine and proline metabolism AMINO ACID METABOLISMUnclassified OTHERSUnclassified OTHERSPurine metabolism NUCLEOTIDE METABOLISMArginine and proline metabolism AMINO ACID METABOLISMPurine metabolism NUCLEOTIDE METABOLISMArginine and proline metabolism AMINO ACID METABOLISMArginine and proline metabolism AMINO ACID METABOLISMHistidine metabolism AMINO ACID METABOLISMPeptidases|Purine metabolism ENZYME FAMILIES|NUCLEOTIDE METABOLISMAtrazine degradation|Cytosolic DNA-sensing pathw IMMUNE SYSTEM|NUCLEOTIDE METABOLISM|TRANSCRIPTION|XENOBIOTICS BIODEGRADATION AND METABOLISMArginine and proline metabolism|Pyrimidine metab AMINO ACID METABOLISM|NUCLEOTIDE METABOLISMOne carbon pool by folate|Purine metabolism METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISMPyrimidine metabolism|Secretion system MEMBRANE TRANSPORT|NUCLEOTIDE METABOLISMPyrimidine metabolism NUCLEOTIDE METABOLISMFolate biosynthesis METABOLISM OF COFACTORS AND VITAMINSHistidine metabolism AMINO ACID METABOLISMPurine metabolism NUCLEOTIDE METABOLISMUnclassified OTHERSRiboflavin metabolism METABOLISM OF COFACTORS AND VITAMINSFolate biosynthesis|Methane metabolism ENERGY METABOLISM|METABOLISM OF COFACTORS AND VITAMINSUnclassified NUCLEOTIDE METABOLISMUnclassified OTHERSPurine metabolism NUCLEOTIDE METABOLISMPrimary immunodeficiency|Purine metabolism IMMUNE SYSTEM DISEASES|NUCLEOTIDE METABOLISMCellular antigens|Drug metabolism - other enzyme IMMUNE SYSTEM|IMMUNE SYSTEM DISEASES|NUCLEOTIDE METABOLISM|SIGNALING MOLECULES AND INTERACTION|XENOBIOTICS BIODEGRADATION AND METABOLISMPurine metabolism NUCLEOTIDE METABOLISMGlyoxylate and dicarboxylate metabolism|One carboCARBOHYDRATE METABOLISM|METABOLISM OF COFACTORS AND VITAMINS

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Benzoate degradation via CoA ligation|Cyanoamin AMINO ACID METABOLISM|ENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDS|XENOBIOTICS BIODEGRADATION AND METABOLISMCyanoamino acid metabolism METABOLISM OF OTHER AMINO ACIDSThiamine metabolism|Transcription factors METABOLISM OF COFACTORS AND VITAMINS|TRANSCRIPTIONAtrazine degradation XENOBIOTICS BIODEGRADATION AND METABOLISMAtrazine degradation XENOBIOTICS BIODEGRADATION AND METABOLISMAmino sugar and nucleotide sugar metabolism|UnclaCARBOHYDRATE METABOLISMPropanoate metabolism CARBOHYDRATE METABOLISMDNA repair and recombination proteins|DNA replic OTHERS|REPLICATION AND REPAIRChromosome|Cytosolic DNA-sensing pathway|DNA repaFOLDING, SORTING AND DEGRADATION|GENERAL FUNCTION PREDICTION ONLY|GLYCAN BIOSYNTHESIS AND METABOLISM|IMMUNE SYSTEM|NUCLEOTIDE METABOLISM|OTHERS|REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINS|TRANSCRIPTION|TRANSLATION|TRANSLATION PROTEINS|TRANSPORT AND CATABOLISMChromosome|Oxidative phosphorylation ENERGY METABOLISM|REPLICATION AND REPAIRPurine metabolism NUCLEOTIDE METABOLISMGlycerophospholipid metabolism|Purine metabolis LIPID METABOLISM|NUCLEOTIDE METABOLISMPurine metabolism|Thiamine metabolism METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISMGlycerophospholipid metabolism|Purine metabolis LIPID METABOLISM|NUCLEOTIDE METABOLISMPurine metabolism|Pyrimidine metabolism NUCLEOTIDE METABOLISMDrug metabolism - other enzymes|Purine metaboli NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMNicotinate and nicotinamide metabolism|Peroxiso METABOLISM OF COFACTORS AND VITAMINS|TRANSPORT AND CATABOLISMDNA repair and recombination proteins|Pyrimidine NUCLEOTIDE METABOLISM|REPLICATION AND REPAIRGlycerophospholipid metabolism LIPID METABOLISMPeptidoglycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISMPurine metabolism NUCLEOTIDE METABOLISMHistidine metabolism AMINO ACID METABOLISMPurine metabolism NUCLEOTIDE METABOLISMPurine metabolism NUCLEOTIDE METABOLISMUnclassified OTHERSN-Glycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISMNicotinate and nicotinamide metabolism|Purine meMETABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISM|OTHERSCellular antigens|Purine metabolism|Pyrimidine meNUCLEOTIDE METABOLISM|SIGNALING MOLECULES AND INTERACTIONGlycerophospholipid metabolism|Purine metabolis LIPID METABOLISM|NUCLEOTIDE METABOLISMLysosome|Purine metabolism|Pyrimidine metaboli NUCLEOTIDE METABOLISM|TRANSPORT AND CATABOLISMBenzoate degradation via CoA ligation|Pyruvate me CARBOHYDRATE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMCellular antigens|Nicotinate and nicotinamide me CARBOHYDRATE METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISM|SIGNALING MOLECULES AND INTERACTIONABC transporters|Transporters|Unclassified ENERGY METABOLISM|MEMBRANE TRANSPORT|OTHERSUnclassified ENERGY METABOLISMTwo-component system SIGNAL TRANSDUCTIONAlzheimer's disease|Bacterial motility proteins|Bac CELL MOTILITY|ENERGY METABOLISM|FOLDING, SORTING AND DEGRADATION|INFECTIOUS DISEASES|MEMBRANE TRANSPORT|NEURODEGENERATIVE DISEASES|TRANSPORT AND CATABOLISMUnclassified OTHER TRANSPORTERSABC transporters|Transporters|Unclassified ENERGY METABOLISM|MEMBRANE TRANSPORTABC transporters|Transporters MEMBRANE TRANSPORTUnclassified ENERGY METABOLISMABC transporters|Transporters MEMBRANE TRANSPORTABC transporters|Transporters|Unclassified ENERGY METABOLISM|MEMBRANE TRANSPORTUnclassified ENERGY METABOLISMABC transporters|Transporters|Unclassified ENERGY METABOLISM|MEMBRANE TRANSPORTABC transporters|Transporters|Unclassified ENERGY METABOLISM|MEMBRANE TRANSPORTABC transporters|Transporters|Unclassified ENERGY METABOLISM|MEMBRANE TRANSPORT

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Unclassified ENERGY METABOLISMABC transporters|Transporters|Unclassified ENERGY METABOLISM|MEMBRANE TRANSPORTABC transporters|Transporters|Unclassified ENERGY METABOLISM|MEMBRANE TRANSPORTABC transporters|Transporters|Unclassified ENERGY METABOLISM|MEMBRANE TRANSPORTABC transporters|Transporters MEMBRANE TRANSPORTABC transporters|Transporters|Unclassified ENERGY METABOLISM|MEMBRANE TRANSPORTUnclassified ENERGY METABOLISMABC transporters|Transporters|Unclassified ENERGY METABOLISM|MEMBRANE TRANSPORTABC transporters|Transporters|Unclassified ENERGY METABOLISM|MEMBRANE TRANSPORTUnclassified ENERGY METABOLISMOxidative phosphorylation ENERGY METABOLISMAlzheimer's disease|Calcium signaling pathway|UnclENERGY METABOLISM|NEURODEGENERATIVE DISEASES|SIGNAL TRANSDUCTIONAldosterone-regulated sodium reabsorption|CardiacCIRCULATORY SYSTEM|EXCRETORY SYSTEMPurine metabolism NUCLEOTIDE METABOLISMUnclassified OTHERSVasopressin-regulated water reabsorption EXCRETORY SYSTEMUnclassified OTHERSPlant-pathogen interaction|Translation factors ENVIRONMENTAL ADAPTATION|TRANSLATIONEndocytosis|Fc gamma R-mediated phagocytosis IMMUNE SYSTEM|TRANSPORT AND CATABOLISM1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DD AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMStyrene degradation|Tyrosine metabolism AMINO ACID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMTryptophan metabolism AMINO ACID METABOLISMAtrazine degradation XENOBIOTICS BIODEGRADATION AND METABOLISMUnclassified OTHERS1,2-Dichloroethane degradation|gamma-HexachloroXENOBIOTICS BIODEGRADATION AND METABOLISM1,2-Dichloroethane degradation|3-Chloroacrylic a XENOBIOTICS BIODEGRADATION AND METABOLISMAtrazine degradation XENOBIOTICS BIODEGRADATION AND METABOLISMBiosynthesis of type II polyketide backbone|Photos BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|ENERGY METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERSPeroxisome|Unclassified CARBOHYDRATE METABOLISM|OTHERS|TRANSPORT AND CATABOLISM1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DD AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMGlycolysis / Gluconeogenesis CARBOHYDRATE METABOLISMPantothenate and CoA biosynthesis|beta-Alanine mMETABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDSAlanine, aspartate and glutamate metabolism|Cyst AMINO ACID METABOLISMAlanine, aspartate and glutamate metabolism|Buta AMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|METABOLIC DISEASES|METABOLISM OF OTHER AMINO ACIDSArginine and proline metabolism|Glutathione meta AMINO ACID METABOLISM|METABOLISM OF OTHER AMINO ACIDSLysine degradation|Tropane, piperidine and pyridineAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITESArginine and proline metabolism AMINO ACID METABOLISMGlyoxylate and dicarboxylate metabolism CARBOHYDRATE METABOLISMCysteine and methionine metabolism|Glycine, serin AMINO ACID METABOLISMPurine metabolism NUCLEOTIDE METABOLISMHistidine metabolism AMINO ACID METABOLISMDrug metabolism - other enzymes|Pyrimidine meta NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMIsoquinoline alkaloid biosynthesis|Tyrosine metabo AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITESBetalain biosynthesis|Histidine metabolism|Indole AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITESArginine and proline metabolism|Pyruvate metabol AMINO ACID METABOLISM|CARBOHYDRATE METABOLISMCarbon fixation in photosynthetic organisms|PyruvaCARBOHYDRATE METABOLISM|ENERGY METABOLISM

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Adipocytokine signaling pathway|Citrate cycle (TCA CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEMTerpenoid backbone biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITESPantothenate and CoA biosynthesis METABOLISM OF COFACTORS AND VITAMINSPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSCarbon fixation in photosynthetic organisms|Glyoxy CARBOHYDRATE METABOLISM|ENERGY METABOLISMPropanoate metabolism CARBOHYDRATE METABOLISMBenzoate degradation via hydroxylation XENOBIOTICS BIODEGRADATION AND METABOLISMTryptophan metabolism AMINO ACID METABOLISMGlyoxylate and dicarboxylate metabolism CARBOHYDRATE METABOLISMPhenylalanine, tyrosine and tryptophan biosynthesi AMINO ACID METABOLISMCarbon fixation in photosynthetic organisms|Citrat CARBOHYDRATE METABOLISM|ENERGY METABOLISMButanoate metabolism|C5-Branched dibasic acid m CARBOHYDRATE METABOLISMArginine and proline metabolism|Cysteine and met AMINO ACID METABOLISMGlycerophospholipid metabolism LIPID METABOLISMTyrosine metabolism AMINO ACID METABOLISMBenzoate degradation via hydroxylation|Toluene anXENOBIOTICS BIODEGRADATION AND METABOLISMBenzoate degradation via CoA ligation|Butanoate CARBOHYDRATE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMUnclassified OTHERSUnclassified METABOLISM OF COFACTORS AND VITAMINSGlyoxylate and dicarboxylate metabolism CARBOHYDRATE METABOLISMPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSPhosphonate and phosphinate metabolism METABOLISM OF OTHER AMINO ACIDSAscorbate and aldarate metabolism|Pentose and gluCARBOHYDRATE METABOLISMPeroxisome|Propanoate metabolism|beta-Alanine CARBOHYDRATE METABOLISM|METABOLISM OF OTHER AMINO ACIDS|TRANSPORT AND CATABOLISMCarbohydrate metabolism|Cytochrome P450|FructoseAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|ENZYME FAMILIES|LIPID METABOLISM|OTHERS|XENOBIOTICS BIODEGRADATION AND METABOLISMCarbon fixation in photosynthetic organisms|Fruc CARBOHYDRATE METABOLISM|ENERGY METABOLISMArginine and proline metabolism|Glyoxylate and d AMINO ACID METABOLISM|CARBOHYDRATE METABOLISMFructose and mannose metabolism CARBOHYDRATE METABOLISMFructose and mannose metabolism|Pentose and glucCARBOHYDRATE METABOLISMAscorbate and aldarate metabolism CARBOHYDRATE METABOLISMGalactose metabolism CARBOHYDRATE METABOLISMCarbon fixation in photosynthetic organisms ENERGY METABOLISMFolate biosynthesis METABOLISM OF COFACTORS AND VITAMINSSphingolipid metabolism LIPID METABOLISMPentose phosphate pathway CARBOHYDRATE METABOLISMGalactose metabolism CARBOHYDRATE METABOLISMMethane metabolism|Pentose and glucuronate inteCARBOHYDRATE METABOLISM|ENERGY METABOLISMGlycine, serine and threonine metabolism AMINO ACID METABOLISMCarbon fixation in photosynthetic organisms|Met CARBOHYDRATE METABOLISM|ENERGY METABOLISMBiosynthesis of siderophore group nonribosomal pe AMINO ACID METABOLISM|BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|CARBOHYDRATE METABOLISMGlyoxylate and dicarboxylate metabolism CARBOHYDRATE METABOLISMArginine and proline metabolism|Glyoxylate and d AMINO ACID METABOLISM|CARBOHYDRATE METABOLISMBenzoate degradation via hydroxylation|C5-BrancheCARBOHYDRATE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMPhenylalanine, tyrosine and tryptophan biosynthesi AMINO ACID METABOLISMAmino sugar and nucleotide sugar metabolism CARBOHYDRATE METABOLISMPropanoate metabolism CARBOHYDRATE METABOLISM

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Unclassified CARBOHYDRATE METABOLISMUbiquinone and other terpenoid-quinone biosynthesMETABOLISM OF COFACTORS AND VITAMINSFolate biosynthesis METABOLISM OF COFACTORS AND VITAMINS1,4-Dichlorobenzene degradation|Benzoate degradaAMINO ACID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMButanoate metabolism|Peroxisome|Synthesis and degAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|LIPID METABOLISM|TRANSPORT AND CATABOLISMUbiquinone and other terpenoid-quinone biosynthesMETABOLISM OF COFACTORS AND VITAMINSCitrate cycle (TCA cycle)|Two-component system CARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTION1- and 2-Methylnaphthalene degradation|UbiquinoneMETABOLISM OF COFACTORS AND VITAMINS|REPLICATION, RECOMBINATION AND REPAIR PROTEINS|XENOBIOTICS BIODEGRADATION AND METABOLISMNitrogen metabolism|Tryptophan metabolism AMINO ACID METABOLISM|ENERGY METABOLISMRiboflavin metabolism METABOLISM OF COFACTORS AND VITAMINSNitrogen metabolism|Tyrosine metabolism AMINO ACID METABOLISM|ENERGY METABOLISMDNA repair and recombination proteins REPLICATION AND REPAIRAmino sugar and nucleotide sugar metabolism|UnclaCARBOHYDRATE METABOLISM|OTHERS1- and 2-Methylnaphthalene degradation|Amino sugarAMINO ACID METABOLISM|BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|XENOBIOTICS BIODEGRADATION AND METABOLISMNitrogen metabolism ENERGY METABOLISMPhenylalanine, tyrosine and tryptophan biosynthesi AMINO ACID METABOLISMNitrogen metabolism ENERGY METABOLISMCysteine and methionine metabolism AMINO ACID METABOLISMGlycolysis / Gluconeogenesis|RNA degradation CARBOHYDRATE METABOLISM|FOLDING, SORTING AND DEGRADATIONUbiquinone and other terpenoid-quinone biosynthesMETABOLISM OF COFACTORS AND VITAMINSPentose phosphate pathway CARBOHYDRATE METABOLISMBenzoate degradation via CoA ligation|Biosynthesi AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMValine, leucine and isoleucine degradation AMINO ACID METABOLISMHistidine metabolism AMINO ACID METABOLISMCitrate cycle (TCA cycle)|Pathways in cancer|ReductCANCERS|CARBOHYDRATE METABOLISM|ENERGY METABOLISMGlycine, serine and threonine metabolism|PhenylalaAMINO ACID METABOLISMCysteine and methionine metabolism|Glycine, seri AMINO ACID METABOLISM|METABOLISM OF OTHER AMINO ACIDSPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSGlycerolipid metabolism LIPID METABOLISMCitrate cycle (TCA cycle)|Glyoxylate and dicarboxyl CARBOHYDRATE METABOLISM|ENERGY METABOLISMGlycerolipid metabolism LIPID METABOLISMGlyoxylate and dicarboxylate metabolism CARBOHYDRATE METABOLISMC5-Branched dibasic acid metabolism|Valine, leucineAMINO ACID METABOLISM|CARBOHYDRATE METABOLISMC5-Branched dibasic acid metabolism|Valine, leucineAMINO ACID METABOLISM|CARBOHYDRATE METABOLISMPentose phosphate pathway CARBOHYDRATE METABOLISMAscorbate and aldarate metabolism CARBOHYDRATE METABOLISMAscorbate and aldarate metabolism CARBOHYDRATE METABOLISMAscorbate and aldarate metabolism CARBOHYDRATE METABOLISMInositol phosphate metabolism CARBOHYDRATE METABOLISMAmino sugar and nucleotide sugar metabolism CARBOHYDRATE METABOLISMBiosynthesis of vancomycin group antibiotics|PolykeBIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|BIOSYNTHESIS OF SECONDARY METABOLITESAmino sugar and nucleotide sugar metabolism|Fru CARBOHYDRATE METABOLISMHistidine metabolism AMINO ACID METABOLISMPhenylalanine, tyrosine and tryptophan biosynthesi AMINO ACID METABOLISMLysine biosynthesis AMINO ACID METABOLISMButanoate metabolism CARBOHYDRATE METABOLISM

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Galactose metabolism CARBOHYDRATE METABOLISMFatty acid biosynthesis|Lipid biosynthesis proteins LIPID METABOLISMPentose and glucuronate interconversions CARBOHYDRATE METABOLISMPyrimidine metabolism NUCLEOTIDE METABOLISMPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSAmino sugar and nucleotide sugar metabolism CARBOHYDRATE METABOLISMPropanoate metabolism CARBOHYDRATE METABOLISMPentose and glucuronate interconversions CARBOHYDRATE METABOLISM1,4-Dichlorobenzene degradation|Benzoate degradaAMINO ACID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMPantothenate and CoA biosynthesis|Valine, leucine AMINO ACID METABOLISM|METABOLISM OF COFACTORS AND VITAMINSFructose and mannose metabolism CARBOHYDRATE METABOLISMUnclassified METABOLISM OF COFACTORS AND VITAMINSUnclassified OTHERSUnclassified OTHERSUnclassified OTHERSPentose and glucuronate interconversions CARBOHYDRATE METABOLISMUnclassified OTHERSUnclassified OTHERSFructose and mannose metabolism CARBOHYDRATE METABOLISMPentose and glucuronate interconversions CARBOHYDRATE METABOLISMPentose and glucuronate interconversions CARBOHYDRATE METABOLISMGlycine, serine and threonine metabolism|Vitamin AMINO ACID METABOLISM|METABOLISM OF COFACTORS AND VITAMINSFolate biosynthesis METABOLISM OF COFACTORS AND VITAMINSPyruvate metabolism CARBOHYDRATE METABOLISMPhenylalanine, tyrosine and tryptophan biosynthesi AMINO ACID METABOLISMPhenylalanine, tyrosine and tryptophan biosynthesi AMINO ACID METABOLISMBase excision repair|DNA repair and recombination OTHERS|REPLICATION AND REPAIRBase excision repair|DNA repair and recombination REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINSUbiquinone and other terpenoid-quinone biosynthesMETABOLISM OF COFACTORS AND VITAMINSMethane metabolism ENERGY METABOLISMAlanine, aspartate and glutamate metabolism|Nitr AMINO ACID METABOLISM|ENERGY METABOLISMArginine and proline metabolism AMINO ACID METABOLISMUnclassified AMINO ACID METABOLISMCysteine and methionine metabolism|Glycine, seri AMINO ACID METABOLISMGlycine, serine and threonine metabolism AMINO ACID METABOLISMGlycine, serine and threonine metabolism|Valine, leAMINO ACID METABOLISMC5-Branched dibasic acid metabolism|Nitrogen met CARBOHYDRATE METABOLISM|ENERGY METABOLISMHistidine metabolism|Nitrogen metabolism AMINO ACID METABOLISM|ENERGY METABOLISMOne carbon pool by folate METABOLISM OF COFACTORS AND VITAMINSGlycerophospholipid metabolism LIPID METABOLISMAlanine, aspartate and glutamate metabolism|ArginAMINO ACID METABOLISMAlanine, aspartate and glutamate metabolism|Puri AMINO ACID METABOLISM|NUCLEOTIDE METABOLISMGlucosinolate biosynthesis|Tryptophan metabolism|AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITESCysteine and methionine metabolism|Glycine, seri AMINO ACID METABOLISM|ENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDSCysteine and methionine metabolism|Selenoamino AMINO ACID METABOLISM|METABOLISM OF OTHER AMINO ACIDSCysteine and methionine metabolism AMINO ACID METABOLISM

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Selenoamino acid metabolism|Thiamine metabolis METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDSUnclassified METABOLISM OF COFACTORS AND VITAMINSCysteine and methionine metabolism|Vibrio choleraAMINO ACID METABOLISM|INFECTIOUS DISEASESMethane metabolism ENERGY METABOLISMMAPK signaling pathway - yeast|Pyruvate metaboli CARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTIONCysteine and methionine metabolism|Nitrogen met AMINO ACID METABOLISM|ENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDSUnclassified CARBOHYDRATE METABOLISM|OTHERSBacterial toxins|Calcium signaling pathway|ChemokCELL COMMUNICATION|CELL GROWTH AND DEATH|CIRCULATORY DISEASES|CIRCULATORY SYSTEM|ENDOCRINE SYSTEM|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|NERVOUS SYSTEM|NUCLEOTIDE METABOLISM|SENSORY SYSTEM|SIGNAL TRANSDUCTION|SIGNALING MOLECULES AND INTERACTIONTerpenoid backbone biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITESInositol phosphate metabolism CARBOHYDRATE METABOLISMGap junction|Long-term depression|Purine metabolCELL COMMUNICATION|CIRCULATORY SYSTEM|NERVOUS SYSTEM|NUCLEOTIDE METABOLISMPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSABC transporters|Carotenoid biosynthesis|LipopolysBIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|MEMBRANE TRANSPORT|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|TRANSLATION PROTEINSUnclassified OTHERSD-Alanine metabolism METABOLISM OF OTHER AMINO ACIDSAlanine, aspartate and glutamate metabolism AMINO ACID METABOLISMD-Glutamine and D-glutamate metabolism METABOLISM OF OTHER AMINO ACIDSArginine and proline metabolism AMINO ACID METABOLISMLysine biosynthesis AMINO ACID METABOLISMBenzoate degradation via hydroxylation|Toluene anXENOBIOTICS BIODEGRADATION AND METABOLISMBiosynthesis of unsaturated fatty acids|Butanoat AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|XENOBIOTICS BIODEGRADATION AND METABOLISMAmino sugar and nucleotide sugar metabolism|AscorBIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|CARBOHYDRATE METABOLISM|FUNCTION UNKNOWN|OTHERSCarbon fixation in photosynthetic organisms|Pento CARBOHYDRATE METABOLISM|ENERGY METABOLISMAmino sugar and nucleotide sugar metabolism CARBOHYDRATE METABOLISMPolyketide sugar unit biosynthesis|Streptomycin bioBIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|BIOSYNTHESIS OF SECONDARY METABOLITESAmino sugar and nucleotide sugar metabolism|LipopCARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISMAmino sugar and nucleotide sugar metabolism|AscoCARBOHYDRATE METABOLISMGlycosaminoglycan biosynthesis - chondroitin sulfat GLYCAN BIOSYNTHESIS AND METABOLISMAmino sugar and nucleotide sugar metabolism|GalaCARBOHYDRATE METABOLISMLipopolysaccharide biosynthesis|LipopolysaccharideGLYCAN BIOSYNTHESIS AND METABOLISMAscorbate and aldarate metabolism CARBOHYDRATE METABOLISMLipopolysaccharide biosynthesis proteins GLYCAN BIOSYNTHESIS AND METABOLISMGlycolysis / Gluconeogenesis CARBOHYDRATE METABOLISMAscorbate and aldarate metabolism|Pentose and gluCARBOHYDRATE METABOLISMAmino sugar and nucleotide sugar metabolism CARBOHYDRATE METABOLISMAmino sugar and nucleotide sugar metabolism CARBOHYDRATE METABOLISMUnclassified OTHERSPropanoate metabolism|Valine, leucine and isoleuc AMINO ACID METABOLISM|CARBOHYDRATE METABOLISMPeroxisome|Primary bile acid biosynthesis LIPID METABOLISM|TRANSPORT AND CATABOLISMStyrene degradation|Tyrosine metabolism AMINO ACID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMCalcium signaling pathway|Chaperones and folding cFOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|NEURODEGENERATIVE DISEASES|PROTEIN FOLDING AND ASSOCIATED PROCESSING|SIGNAL TRANSDUCTION|TRANSCRIPTIONBiosynthesis of ansamycins|Galactose metabolism|IBIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|CARBOHYDRATE METABOLISMCarbon fixation in photosynthetic organisms|Fruct CARBOHYDRATE METABOLISM|ENERGY METABOLISMPentose and glucuronate interconversions CARBOHYDRATE METABOLISM

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Unclassified MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULESFructose and mannose metabolism CARBOHYDRATE METABOLISMHistidine metabolism AMINO ACID METABOLISMPentose and glucuronate interconversions CARBOHYDRATE METABOLISMGlyoxylate and dicarboxylate metabolism CARBOHYDRATE METABOLISMCysteine and methionine metabolism AMINO ACID METABOLISMPhenylalanine, tyrosine and tryptophan biosynthesi AMINO ACID METABOLISMFructose and mannose metabolism CARBOHYDRATE METABOLISMGalactose metabolism CARBOHYDRATE METABOLISMMethane metabolism|Pentose and glucuronate inteCARBOHYDRATE METABOLISM|ENERGY METABOLISMPentose and glucuronate interconversions CARBOHYDRATE METABOLISMFructose and mannose metabolism|Pentose and glucCARBOHYDRATE METABOLISMCarbon fixation in photosynthetic organisms|Pent CARBOHYDRATE METABOLISM|ENERGY METABOLISMAmino sugar and nucleotide sugar metabolism|Fru CARBOHYDRATE METABOLISMAmino sugar and nucleotide sugar metabolism|Glyc CARBOHYDRATE METABOLISMBenzoate degradation via hydroxylation|Fluorene d XENOBIOTICS BIODEGRADATION AND METABOLISMPhenylalanine metabolism|Tyrosine metabolism AMINO ACID METABOLISMPeroxisome|Tyrosine metabolism|Unclassified AMINO ACID METABOLISM|OTHERS|TRANSPORT AND CATABOLISMSteroid hormone biosynthesis LIPID METABOLISMBenzoate degradation via hydroxylation|Tyrosine m AMINO ACID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMTerpenoid backbone biosynthesis BIOSYNTHESIS OF SECONDARY METABOLITESSteroid biosynthesis LIPID METABOLISMBenzoate degradation via CoA ligation|Butanoate AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMAntigen processing and presentation|Chaperones andFOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|INFECTIOUS DISEASES|MEMBRANE TRANSPORT|PROTEIN FOLDING AND ASSOCIATED PROCESSINGUnclassified CARBOHYDRATE METABOLISMArachidonic acid metabolism LIPID METABOLISMArachidonic acid metabolism|Cytochrome P450 ENZYME FAMILIES|LIPID METABOLISMPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSGlycolysis / Gluconeogenesis CARBOHYDRATE METABOLISMAmino sugar and nucleotide sugar metabolism CARBOHYDRATE METABOLISMAmino sugar and nucleotide sugar metabolism|GalaBIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISMAmino sugar and nucleotide sugar metabolism CARBOHYDRATE METABOLISMStarch and sucrose metabolism CARBOHYDRATE METABOLISMPentose phosphate pathway|Purine metabolism CARBOHYDRATE METABOLISM|NUCLEOTIDE METABOLISMAmino sugar and nucleotide sugar metabolism|Fru CARBOHYDRATE METABOLISMPhosphonate and phosphinate metabolism METABOLISM OF OTHER AMINO ACIDSLysine degradation AMINO ACID METABOLISMLysine degradation AMINO ACID METABOLISMPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSBiosynthesis of siderophore group nonribosomal pe BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|METABOLISM OF COFACTORS AND VITAMINSDNA replication proteins|Unclassified GLYCAN BIOSYNTHESIS AND METABOLISM|OTHERS|REPLICATION AND REPAIRC5-Branched dibasic acid metabolism CARBOHYDRATE METABOLISMUnclassified TRANSLATION PROTEINSUnclassified OTHERSStarch and sucrose metabolism CARBOHYDRATE METABOLISMSteroid biosynthesis LIPID METABOLISM

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Purine metabolism NUCLEOTIDE METABOLISMPropanoate metabolism|Valine, leucine and isoleuc AMINO ACID METABOLISM|CARBOHYDRATE METABOLISMPhenylalanine, tyrosine and tryptophan biosynthesi AMINO ACID METABOLISMSteroid biosynthesis LIPID METABOLISMSteroid biosynthesis LIPID METABOLISMUnclassified MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULESUnclassified OTHERSInositol phosphate metabolism|Streptomycin biosynBIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM1,4-Dichlorobenzene degradation|Fluorobenzoate XENOBIOTICS BIODEGRADATION AND METABOLISMChromosome|DNA replication proteins REPLICATION AND REPAIRDNA repair and recombination proteins|DNA replic REPLICATION AND REPAIRChromosome|DNA repair and recombination proteinREPLICATION AND REPAIRLipoic acid metabolism|Lipopolysaccharide biosynthGLYCAN BIOSYNTHESIS AND METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|METABOLISM OF COFACTORS AND VITAMINS|OTHERSUnclassified OTHERSAminoacyl-tRNA biosynthesis TRANSLATIONAminoacyl-tRNA biosynthesis|Selenoamino acid me METABOLISM OF OTHER AMINO ACIDS|TRANSLATIONAminoacyl-tRNA biosynthesis TRANSLATIONAminoacyl-tRNA biosynthesis TRANSLATIOND-Alanine metabolism METABOLISM OF OTHER AMINO ACIDSAminoacyl-tRNA biosynthesis TRANSLATIONAminoacyl-tRNA biosynthesis TRANSLATIONAminoacyl-tRNA biosynthesis TRANSLATIONAminoacyl-tRNA biosynthesis|Porphyrin and chloro METABOLISM OF COFACTORS AND VITAMINS|TRANSLATIONAminoacyl-tRNA biosynthesis TRANSLATIONAminoacyl-tRNA biosynthesis TRANSLATIONAminoacyl-tRNA biosynthesis|Tryptophan metaboli AMINO ACID METABOLISM|TRANSLATIONAminoacyl-tRNA biosynthesis TRANSLATIONAminoacyl-tRNA biosynthesis TRANSLATIONAminoacyl-tRNA biosynthesis TRANSLATIONAminoacyl-tRNA biosynthesis TRANSLATIONAminoacyl-tRNA biosynthesis TRANSLATIONAminoacyl-tRNA biosynthesis TRANSLATIONAminoacyl-tRNA biosynthesis TRANSLATIONAminoacyl-tRNA biosynthesis|Valine, leucine and isoAMINO ACID METABOLISM|TRANSLATIONAminoacyl-tRNA biosynthesis|Valine, leucine and isoAMINO ACID METABOLISM|TRANSLATIONAminoacyl-tRNA biosynthesis TRANSLATIONAminoacyl-tRNA biosynthesis TRANSLATIONAminoacyl-tRNA biosynthesis|Valine, leucine and isoAMINO ACID METABOLISM|TRANSLATIONBenzoate degradation via CoA ligation|Butirosin a BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|LIPID METABOLISM|OTHERS|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMGlycolysis / Gluconeogenesis|Lipid biosynthesis pr CARBOHYDRATE METABOLISM|ENERGY METABOLISM|LIPID METABOLISMPhenylpropanoid biosynthesis|Ubiquinone and otheBIOSYNTHESIS OF SECONDARY METABOLITES|METABOLISM OF COFACTORS AND VITAMINSGlycolysis / Gluconeogenesis|Lipid biosynthesis p CARBOHYDRATE METABOLISM|LIPID METABOLISMButanoate metabolism|Lipid biosynthesis proteins CARBOHYDRATE METABOLISM|LIPID METABOLISMLipid biosynthesis proteins|Propanoate metabolism CARBOHYDRATE METABOLISM|LIPID METABOLISMUnclassified OTHERSFatty acid metabolism LIPID METABOLISM

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Two-component system SIGNAL TRANSDUCTIONUbiquinone and other terpenoid-quinone biosynthesMETABOLISM OF COFACTORS AND VITAMINSAdipocytokine signaling pathway|Fatty acid metabo ENDOCRINE SYSTEM|LIPID METABOLISM|TRANSPORT AND CATABOLISMPhenylalanine metabolism AMINO ACID METABOLISMUnclassified LIPID METABOLISMC5-Branched dibasic acid metabolism|Citrate cycle CARBOHYDRATE METABOLISM|ENERGY METABOLISMUnclassified OTHERSPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSAlanine, aspartate and glutamate metabolism|Cya AMINO ACID METABOLISM|ENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDSPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSArginine and proline metabolism AMINO ACID METABOLISMAlanine, aspartate and glutamate metabolism|Arg AMINO ACID METABOLISM|ENERGY METABOLISM|SIGNAL TRANSDUCTIONNicotinate and nicotinamide metabolism|Nitrogen ENERGY METABOLISM|METABOLISM OF COFACTORS AND VITAMINSGlutathione metabolism METABOLISM OF OTHER AMINO ACIDSBiosynthesis of siderophore group nonribosomal pepBIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|ENVIRONMENTAL ADAPTATION|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|TRANSCRIPTIONPantothenate and CoA biosynthesis|beta-Alanine mMETABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDSLysine biosynthesis|Peptidoglycan biosynthesis AMINO ACID METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISMLysine biosynthesis|Peptidoglycan biosynthesis AMINO ACID METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISMFolate biosynthesis METABOLISM OF COFACTORS AND VITAMINSAldosterone-regulated sodium reabsorption|BladderCANCERS|CELL GROWTH AND DEATH|ENDOCRINE SYSTEM|ENZYME FAMILIES|EXCRETORY SYSTEM|FOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|NEURODEGENERATIVE DISEASES|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|TRANSCRIPTION|TRANSPORT AND CATABOLISMGlutathione metabolism METABOLISM OF OTHER AMINO ACIDSUnclassified OTHERSGlutathione metabolism METABOLISM OF OTHER AMINO ACIDSD-Alanine metabolism|Peptidoglycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISM|METABOLISM OF OTHER AMINO ACIDSPantothenate and CoA biosynthesis METABOLISM OF COFACTORS AND VITAMINSPurine metabolism NUCLEOTIDE METABOLISMPeptidoglycan biosynthesis GLYCAN BIOSYNTHESIS AND METABOLISMD-Glutamine and D-glutamate metabolism|PeptidoglGLYCAN BIOSYNTHESIS AND METABOLISM|METABOLISM OF OTHER AMINO ACIDSD-Glutamine and D-glutamate metabolism|PeptidoglGLYCAN BIOSYNTHESIS AND METABOLISM|METABOLISM OF OTHER AMINO ACIDSOne carbon pool by folate|Purine metabolism METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISMOne carbon pool by folate METABOLISM OF COFACTORS AND VITAMINSBiotin metabolism METABOLISM OF COFACTORS AND VITAMINSPurine metabolism|Unclassified NUCLEOTIDE METABOLISM|OTHERS|TRANSLATION PROTEINSBiotin metabolism METABOLISM OF COFACTORS AND VITAMINSBiotin metabolism METABOLISM OF COFACTORS AND VITAMINSOne carbon pool by folate|Purine metabolism METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISMFatty acid biosynthesis LIPID METABOLISMBiotin metabolism|Pantothenate and CoA biosynthesMETABOLISM OF COFACTORS AND VITAMINS|TRANSCRIPTIONPurine metabolism NUCLEOTIDE METABOLISMPyrimidine metabolism NUCLEOTIDE METABOLISMGlyoxylate and dicarboxylate metabolism|One carboCARBOHYDRATE METABOLISM|METABOLISM OF COFACTORS AND VITAMINSAlanine, aspartate and glutamate metabolism|Puri AMINO ACID METABOLISM|NUCLEOTIDE METABOLISMAlanine, aspartate and glutamate metabolism|ArginAMINO ACID METABOLISMArginine and proline metabolism AMINO ACID METABOLISMBiotin metabolism METABOLISM OF COFACTORS AND VITAMINSNicotinate and nicotinamide metabolism METABOLISM OF COFACTORS AND VITAMINS

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Porphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSDrug metabolism - other enzymes|Peptidases|Puri ENZYME FAMILIES|NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMPurine metabolism NUCLEOTIDE METABOLISMAlanine, aspartate and glutamate metabolism|Nitr AMINO ACID METABOLISM|ENERGY METABOLISM|ENZYME FAMILIESAlanine, aspartate and glutamate metabolism|Pept AMINO ACID METABOLISM|ENZYME FAMILIES|NUCLEOTIDE METABOLISMAminoacyl-tRNA biosynthesis TRANSLATIONAminoacyl-tRNA biosynthesis TRANSLATIONPorphyrin and chlorophyll metabolism METABOLISM OF COFACTORS AND VITAMINSBenzoate degradation via CoA ligation|Ethylbenzen XENOBIOTICS BIODEGRADATION AND METABOLISMCitrate cycle (TCA cycle)|Pyruvate metabolism CARBOHYDRATE METABOLISMFatty acid biosynthesis|Insulin signaling pathway BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|LIPID METABOLISMPropanoate metabolism|Valine, leucine and isoleuc AMINO ACID METABOLISM|CARBOHYDRATE METABOLISMValine, leucine and isoleucine degradation AMINO ACID METABOLISMUnclassified BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITESUnclassified TRANSLATION PROTEINSBase excision repair|DNA repair and recombination REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINSBase excision repair|DNA repair and recombination REPLICATION AND REPAIRUnclassified TRANSCRIPTION RELATED PROTEINSPorphyrin and chlorophyll metabolism|Unclassified METABOLISM OF COFACTORS AND VITAMINS|OTHERSPorphyrin and chlorophyll metabolism|Unclassified METABOLISM OF COFACTORS AND VITAMINS|OTHERS

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BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|CELL GROWTH AND DEATH|ELECTRON TRANSFER CARRIERS|ENERGY METABOLISM|GENERAL FUNCTION PREDICTION ONLY|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|REPLICATION AND REPAIR|TRANSLATION PROTEINS|XENOBIOTICS BIODEGRADATION AND METABOLISMBIOSYNTHESIS OF SECONDARY METABOLITES|ENERGY METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMAMINO ACID METABOLISM|BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|XENOBIOTICS BIODEGRADATION AND METABOLISMAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|ENERGY METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

CARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTIONBIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|BIOSYNTHESIS OF SECONDARY METABOLITES

CARBOHYDRATE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMCARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISMBIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITES

CARBOHYDRATE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMBIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM

CARBOHYDRATE METABOLISM|LIPID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMCARBOHYDRATE METABOLISM|LIPID METABOLISM

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AMINO ACID METABOLISM|CARBOHYDRATE METABOLISM

AMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|ENERGY METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISMAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM

CARBOHYDRATE METABOLISM|LIPID METABOLISM

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|NEURODEGENERATIVE DISEASES|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

CARBOHYDRATE METABOLISM|ENERGY METABOLISMCARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTIONCARBOHYDRATE METABOLISM|ENERGY METABOLISM

CARBOHYDRATE METABOLISM|ENERGY METABOLISM

CARBOHYDRATE METABOLISM|ENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDS|TRANSPORT AND CATABOLISMCARBOHYDRATE METABOLISM|METABOLISM OF OTHER AMINO ACIDS

CARBOHYDRATE METABOLISM|METABOLISM OF OTHER AMINO ACIDS

BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITES

AMINO ACID METABOLISM|CARBOHYDRATE METABOLISM

AMINO ACID METABOLISM|CARBOHYDRATE METABOLISM

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AMINO ACID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS

AMINO ACID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

CARBOHYDRATE METABOLISM|TRANSPORT AND CATABOLISM

BIOSYNTHESIS OF SECONDARY METABOLITES|METABOLISM OF OTHER AMINO ACIDS|XENOBIOTICS BIODEGRADATION AND METABOLISM

CARBOHYDRATE METABOLISM|ENERGY METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

CIRCULATORY SYSTEM|ENERGY METABOLISM|NEURODEGENERATIVE DISEASES

ELECTRON TRANSFER CARRIERS|ENVIRONMENTAL ADAPTATION|METABOLISM OF OTHER AMINO ACIDS|PROTEIN FOLDING AND ASSOCIATED PROCESSING

METABOLISM OF OTHER AMINO ACIDS|PROTEIN FOLDING AND ASSOCIATED PROCESSING|TRANSPORT AND CATABOLISM

AMINO ACID METABOLISM|ENERGY METABOLISM|NEURODEGENERATIVE DISEASES|TRANSPORT AND CATABOLISMAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|ENERGY METABOLISM|IMMUNE SYSTEM DISEASES|OTHERSLIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS

CARBOHYDRATE METABOLISM|ENERGY METABOLISM

CARBOHYDRATE METABOLISM|ENERGY METABOLISM

XENOBIOTICS BIODEGRADATION AND METABOLISMXENOBIOTICS BIODEGRADATION AND METABOLISMLIPID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

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XENOBIOTICS BIODEGRADATION AND METABOLISM

XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|METABOLISM OF COFACTORS AND VITAMINSXENOBIOTICS BIODEGRADATION AND METABOLISMXENOBIOTICS BIODEGRADATION AND METABOLISM

BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITESAMINO ACID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|ENERGY METABOLISM|ENZYME FAMILIES|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CANCERS|GLYCAN BIOSYNTHESIS AND METABOLISM|OTHERS|REPLICATION AND REPAIR|TRANSCRIPTION

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|ENERGY METABOLISM|ENZYME FAMILIES|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISMXENOBIOTICS BIODEGRADATION AND METABOLISMXENOBIOTICS BIODEGRADATION AND METABOLISMXENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|CANCERS|ENVIRONMENTAL ADAPTATION|INFECTIOUS DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|SIGNAL TRANSDUCTION|TRANSPORT AND CATABOLISM

XENOBIOTICS BIODEGRADATION AND METABOLISM

XENOBIOTICS BIODEGRADATION AND METABOLISM

BIOSYNTHESIS OF SECONDARY METABOLITES|ENERGY METABOLISM|LIPID METABOLISMAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|ENZYME FAMILIES|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

CIRCULATORY SYSTEM|ENDOCRINE SYSTEM|ENZYME FAMILIES|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|NEURODEGENERATIVE DISEASES

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AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|ENDOCRINE SYSTEM|METABOLISM OF COFACTORS AND VITAMINS

ENDOCRINE SYSTEM|LIPID METABOLISM|SIGNAL TRANSDUCTION

BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITES|BIOSYNTHESIS OF SECONDARY METABOLITES|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

INORGANIC ION TRANSPORT AND METABOLISM|NEURODEGENERATIVE DISEASES|TRANSPORT AND CATABOLISM

BIOSYNTHESIS OF SECONDARY METABOLITES|NUCLEOTIDE METABOLISM|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMBIOSYNTHESIS OF SECONDARY METABOLITES|NUCLEOTIDE METABOLISM|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMCELL GROWTH AND DEATH|IMMUNE SYSTEM|METABOLISM OF OTHER AMINO ACIDS|NUCLEOTIDE METABOLISM|REPLICATION AND REPAIR

METABOLISM OF COFACTORS AND VITAMINS|OTHERSENERGY METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS

ENERGY METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

BIOSYNTHESIS OF SECONDARY METABOLITES|XENOBIOTICS BIODEGRADATION AND METABOLISMAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|ENERGY METABOLISM|OTHERS|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

CARBOHYDRATE METABOLISM|NEURODEGENERATIVE DISEASES|OTHERSAMINO ACID METABOLISM|CARBOHYDRATE METABOLISMAMINO ACID METABOLISM|METABOLISM OF OTHER AMINO ACIDSCARBOHYDRATE METABOLISM|ENERGY METABOLISM|SIGNAL TRANSDUCTION

AMINO ACID METABOLISM|CARBOHYDRATE METABOLISMAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

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CARBOHYDRATE METABOLISM|ENERGY METABOLISM

BIOSYNTHESIS OF SECONDARY METABOLITES|ENERGY METABOLISM

AMINO ACID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|CARBOHYDRATE METABOLISMAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM

CARBOHYDRATE METABOLISM|ENERGY METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMCARBOHYDRATE METABOLISM|ENERGY METABOLISM

ENERGY METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|LIPID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITESMETABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDS|NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMCARBOHYDRATE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

XENOBIOTICS BIODEGRADATION AND METABOLISM

BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES

ENERGY METABOLISM|TRANSPORT AND CATABOLISMLIPID METABOLISM|TRANSPORT AND CATABOLISM

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ENDOCRINE SYSTEM|LIPID METABOLISM|TRANSPORT AND CATABOLISMCARBOHYDRATE METABOLISM|ENERGY METABOLISM|NEURODEGENERATIVE DISEASES

AMINO ACID METABOLISM|BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITES|BIOSYNTHESIS OF SECONDARY METABOLITES|LIPID METABOLISM|OTHERS|XENOBIOTICS BIODEGRADATION AND METABOLISMCARBOHYDRATE METABOLISM|ENERGY METABOLISM|SIGNAL TRANSDUCTION|XENOBIOTICS BIODEGRADATION AND METABOLISM

XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|LIPID METABOLISM

AMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS

AMINO ACID METABOLISM|LIPID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|ENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDS

AMINO ACID METABOLISM|ENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDS

AMINO ACID METABOLISM|METABOLISM OF COFACTORS AND VITAMINSMETABOLISM OF COFACTORS AND VITAMINS|OTHERSAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|METABOLISM OF OTHER AMINO ACIDSAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|METABOLISM OF OTHER AMINO ACIDS|TRANSPORT AND CATABOLISMAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|XENOBIOTICS BIODEGRADATION AND METABOLISM

ENERGY METABOLISM|GENERAL FUNCTION PREDICTION ONLY|OTHERS

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ENERGY METABOLISM|METABOLISM OF COFACTORS AND VITAMINS

BIOSYNTHESIS OF SECONDARY METABOLITES|OTHERS

METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISMCARBOHYDRATE METABOLISM|METABOLISM OF COFACTORS AND VITAMINS

AMINO ACID METABOLISM|TRANSPORT AND CATABOLISM

AMINO ACID METABOLISM|METABOLISM OF OTHER AMINO ACIDS

ENERGY METABOLISM|NEURODEGENERATIVE DISEASES

ENERGY METABOLISM|NEURODEGENERATIVE DISEASES

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ELECTRON TRANSFER CARRIERS|SIGNAL TRANSDUCTIONBIOSYNTHESIS OF SECONDARY METABOLITES|NUCLEOTIDE METABOLISM

AMINO ACID METABOLISM|CARBOHYDRATE METABOLISM

FOLDING, SORTING AND DEGRADATION|PROTEIN FOLDING AND ASSOCIATED PROCESSING

ELECTRON TRANSFER CARRIERS|ENERGY METABOLISMENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDSXENOBIOTICS BIODEGRADATION AND METABOLISM

CIRCULATORY SYSTEM|ENERGY METABOLISM|NEURODEGENERATIVE DISEASES

BIOSYNTHESIS OF SECONDARY METABOLITES|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|OTHERSGLYCAN BIOSYNTHESIS AND METABOLISM|OTHERS|REPLICATION AND REPAIRAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CELL MOTILITY|ENZYME FAMILIES|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|MEMBRANE TRANSPORT|METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDS|REPLICATION AND REPAIR|TRANSCRIPTION|TRANSLATION PROTEINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

REPLICATION, RECOMBINATION AND REPAIR PROTEINS

CELL GROWTH AND DEATH|REPLICATION AND REPAIR|TRANSCRIPTIONAMINO ACID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS

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BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITESMETABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISM

AMINO ACID METABOLISM|REPLICATION AND REPAIR

AMINO ACID METABOLISM|CELL COMMUNICATION|REPLICATION AND REPAIRMETABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISM

XENOBIOTICS BIODEGRADATION AND METABOLISMREPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINS|RESTRICTION ENZYME|TRANSLATION PROTEINS

MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES

CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|OTHERSAMINO ACID METABOLISM|ENERGY METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDSAMINO ACID METABOLISM|ENERGY METABOLISM|METABOLISM OF COFACTORS AND VITAMINS

METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISMMETABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISMAMINO ACID METABOLISM|METABOLISM OF COFACTORS AND VITAMINSMETABOLISM OF COFACTORS AND VITAMINS|TRANSLATIONBIOSYNTHESIS OF SECONDARY METABOLITES|PROTEIN FOLDING AND ASSOCIATED PROCESSING

AMINO ACID METABOLISM|ENZYME FAMILIES|NUCLEOTIDE METABOLISM

BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|CARBOHYDRATE METABOLISM|ENERGY METABOLISM

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AMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|METABOLISM OF COFACTORS AND VITAMINS

AMINO ACID METABOLISM|BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GENERAL FUNCTION PREDICTION ONLY|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|MEMBRANE TRANSPORT|OTHERS|PROTEIN FOLDING AND ASSOCIATED PROCESSING|REPLICATION AND REPAIR|TRANSLATION PROTEINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

ENERGY METABOLISM|METABOLISM OF COFACTORS AND VITAMINS

BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITES

AMINO ACID METABOLISM|ENDOCRINE SYSTEM|LIPID METABOLISM|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMBIOSYNTHESIS OF SECONDARY METABOLITES|ENZYME FAMILIES

ENDOCRINE SYSTEM|LIPID METABOLISM|TRANSPORT AND CATABOLISM

LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS

AMINO ACID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS

LIPID METABOLISM|TRANSPORT AND CATABOLISM

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CANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|ENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|OTHERS|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|TRANSCRIPTION

AMINO ACID METABOLISM|CARBOHYDRATE METABOLISM

GLYCAN BIOSYNTHESIS AND METABOLISM|TRANSPORT AND CATABOLISM

CARBOHYDRATE METABOLISM|METABOLISM OF OTHER AMINO ACIDS

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|LIPID METABOLISM|SIGNAL TRANSDUCTION|XENOBIOTICS BIODEGRADATION AND METABOLISMBIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|LIPID METABOLISM

BIOSYNTHESIS OF SECONDARY METABOLITES|GLYCAN BIOSYNTHESIS AND METABOLISM

IMMUNE SYSTEM|NEURODEGENERATIVE DISEASES|OTHERS|SIGNALING MOLECULES AND INTERACTION|SPORULATIONENZYME FAMILIES|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|SIGNALING MOLECULES AND INTERACTION

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|LIPID METABOLISMAMINO ACID METABOLISM|CARBOHYDRATE METABOLISMAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM

CARBOHYDRATE METABOLISM|ENERGY METABOLISM

GLYCAN BIOSYNTHESIS AND METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|OTHERSBIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|CELLULAR PROCESSES AND SIGNALING|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|SIGNALING MOLECULES AND INTERACTIONCARBOHYDRATE METABOLISM|ENDOCRINE SYSTEMCARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTION

CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|GLYCAN BIOSYNTHESIS AND METABOLISM

CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM

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GLYCAN BIOSYNTHESIS AND METABOLISM|REPLICATION AND REPAIR

GLYCAN BIOSYNTHESIS AND METABOLISM|SIGNALING MOLECULES AND INTERACTION

GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISMCARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM

CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

GLYCAN BIOSYNTHESIS AND METABOLISM|OTHERS

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CARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTION

GLYCAN BIOSYNTHESIS AND METABOLISM|OTHERS

GLYCAN BIOSYNTHESIS AND METABOLISM|OTHERS

GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|GLYCAN BIOSYNTHESIS AND METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISM|OTHERS|SIGNALING MOLECULES AND INTERACTION|TRANSLATION PROTEINSMETABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISMNUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|ENZYME FAMILIES|NUCLEOTIDE METABOLISM

NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

NUCLEOTIDE METABOLISM|REPLICATION AND REPAIR|SIGNALING MOLECULES AND INTERACTION

CANCERS|NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

GLYCAN BIOSYNTHESIS AND METABOLISM|SIGNALING MOLECULES AND INTERACTION

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|ENERGY METABOLISM|METABOLISM OF COFACTORS AND VITAMINS

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AMINO ACID METABOLISM|METABOLISM OF OTHER AMINO ACIDS

METABOLISM OF OTHER AMINO ACIDS|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

LIPID METABOLISM|TRANSPORT AND CATABOLISM

AMINO ACID METABOLISM|ENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDSAMINO ACID METABOLISM|ENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDS

AMINO ACID METABOLISM|METABOLISM OF OTHER AMINO ACIDS

CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM

GLYCAN BIOSYNTHESIS AND METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERSAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|SIGNAL TRANSDUCTIONAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|ENERGY METABOLISM

AMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|ENZYME FAMILIES

AMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|METABOLISM OF OTHER AMINO ACIDSAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|METABOLISM OF OTHER AMINO ACIDS

AMINO ACID METABOLISM|METABOLISM OF OTHER AMINO ACIDSAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|METABOLISM OF OTHER AMINO ACIDS

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AMINO ACID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|METABOLISM OF COFACTORS AND VITAMINSAMINO ACID METABOLISM|METABOLISM OF COFACTORS AND VITAMINSAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES

AMINO ACID METABOLISM|CELLULAR PROCESSES AND SIGNALING|GLYCAN BIOSYNTHESIS AND METABOLISM|SIGNAL TRANSDUCTIONCARBOHYDRATE METABOLISM|FUNCTION UNKNOWN|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|SIGNAL TRANSDUCTION MECHANISMS|TRANSLATION PROTEINSBIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|METABOLIC DISEASES

CARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTION

CARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTION|TRANSPORT AND CATABOLISM

CARBOHYDRATE METABOLISM|CELL MOTILITY|SIGNAL TRANSDUCTION

CANCERS|CARBOHYDRATE METABOLISM|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|ENDOCRINE SYSTEM|EXCRETORY SYSTEM|IMMUNE SYSTEM|METABOLIC DISEASES|NERVOUS SYSTEM|SIGNAL TRANSDUCTIONCARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTION

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BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|METABOLIC DISEASES

NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

ENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDS|NUCLEOTIDE METABOLISM

ENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|LIPID METABOLISMAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|LIPID METABOLISM

BIOSYNTHESIS OF SECONDARY METABOLITES|TRANSPORT AND CATABOLISM

CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|ENERGY METABOLISM|METABOLIC DISEASES|NUCLEOTIDE METABOLISM

NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

CARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTIONCARBOHYDRATE METABOLISM|CELL MOTILITY|IMMUNE SYSTEM|SIGNAL TRANSDUCTION|TRANSPORT AND CATABOLISMCARBOHYDRATE METABOLISM|MEMBRANE TRANSPORT|UNPROCESSED

IMMUNE SYSTEM|LIPID METABOLISM|SIGNAL TRANSDUCTION

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CANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|DEVELOPMENT|ENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|ENZYME FAMILIES|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|METABOLIC DISEASES|NERVOUS SYSTEM|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMS|SIGNALING MOLECULES AND INTERACTION|TRANSPORT AND CATABOLISMCANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY DISEASES|DEVELOPMENT|ENDOCRINE SYSTEM|ENZYME FAMILIES|IMMUNE SYSTEM|IMMUNE SYSTEM DISEASES|INFECTIOUS DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMS|SIGNALING MOLECULES AND INTERACTION|TRANSPORT AND CATABOLISMCELL GROWTH AND DEATH|ENZYME FAMILIES|MEMBRANE TRANSPORT|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMSCANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY DISEASES|CIRCULATORY SYSTEM|DEVELOPMENT|ENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|ENZYME FAMILIES|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|MEMBRANE TRANSPORT|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMS|SIGNALING MOLECULES AND INTERACTION|SPORULATION|TRANSCRIPTION|TRANSPORT AND CATABOLISMCANCERS|CELL GROWTH AND DEATH|ENDOCRINE SYSTEM|ENZYME FAMILIES|IMMUNE SYSTEM|INFECTIOUS DISEASES|METABOLIC DISEASES|NERVOUS SYSTEM|SIGNAL TRANSDUCTIONCELL COMMUNICATION|CELL GROWTH AND DEATH|CIRCULATORY DISEASES|CIRCULATORY SYSTEM|ENDOCRINE SYSTEM|ENZYME FAMILIES|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|SENSORY SYSTEM|SIGNAL TRANSDUCTION|TRANSPORT AND CATABOLISMCELL COMMUNICATION|ENZYME FAMILIES|NERVOUS SYSTEM|SENSORY SYSTEMCANCERS|CELL COMMUNICATION|CIRCULATORY SYSTEM|ENDOCRINE SYSTEM|ENZYME FAMILIES|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|NERVOUS SYSTEM|SIGNAL TRANSDUCTION|TRANSPORT AND CATABOLISMENZYME FAMILIES|IMMUNE SYSTEM|TRANSPORT AND CATABOLISMCANCERS|CELL GROWTH AND DEATH|ENDOCRINE SYSTEM|ENZYME FAMILIES|NERVOUS SYSTEM|SENSORY SYSTEM|SIGNAL TRANSDUCTIONCELL COMMUNICATION|CELL MOTILITY|CIRCULATORY SYSTEM|ENZYME FAMILIES|SIGNAL TRANSDUCTIONENZYME FAMILIES|IMMUNE SYSTEM|NERVOUS SYSTEMCELL GROWTH AND DEATH|ENDOCRINE SYSTEM|ENZYME FAMILIES|REPLICATION AND REPAIRCANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|DEVELOPMENT|ENDOCRINE SYSTEM|ENZYME FAMILIES|IMMUNE SYSTEM|NEURODEGENERATIVE DISEASES|REPLICATION AND REPAIR|TRANSCRIPTIONCANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY SYSTEM|DEVELOPMENT|ENDOCRINE SYSTEM|ENZYME FAMILIES|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|METABOLIC DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|SIGNALING MOLECULES AND INTERACTIONCELL COMMUNICATION|CELL GROWTH AND DEATH|ENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|INFECTIOUS DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|SIGNAL TRANSDUCTIONCANCERS|CELL COMMUNICATION|ENZYME FAMILIES|SIGNAL TRANSDUCTION|SIGNALING MOLECULES AND INTERACTION|TRANSPORT AND CATABOLISMENZYME FAMILIES|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMSCELL GROWTH AND DEATH|ENZYME FAMILIES|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION MECHANISMS|TRANSCRIPTIONCANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY SYSTEM|DEVELOPMENT|ENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|ENZYME FAMILIES|IMMUNE SYSTEM|INFECTIOUS DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|SIGNAL TRANSDUCTIONENZYME FAMILIES|MEMBRANE TRANSPORT|SIGNAL TRANSDUCTION

CELL MOTILITY|ENZYME FAMILIES|INFECTIOUS DISEASES|OTHERS|SIGNAL TRANSDUCTIONAMINO ACID METABOLISM|CARBOHYDRATE METABOLISMCARBOHYDRATE METABOLISM|METABOLISM OF OTHER AMINO ACIDS

AMINO ACID METABOLISM|ENERGY METABOLISM|NUCLEOTIDE METABOLISMCARBOHYDRATE METABOLISM|ENERGY METABOLISM

ENERGY METABOLISM|FOLDING, SORTING AND DEGRADATION

BIOSYNTHESIS OF SECONDARY METABOLITES|TRANSPORT AND CATABOLISM

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CARBOHYDRATE METABOLISM|NUCLEOTIDE METABOLISM

BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|CARBOHYDRATE METABOLISM|FOLDING, SORTING AND DEGRADATION|GLYCAN BIOSYNTHESIS AND METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISM|OTHERS|REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINS|UNPROCESSED

LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDSLIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS

FOLDING, SORTING AND DEGRADATION|REPLICATION AND REPAIR

BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|BIOSYNTHESIS OF SECONDARY METABOLITES

ENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDS|NUCLEOTIDE METABOLISM

NUCLEOTIDE METABOLISM|REPLICATION AND REPAIRREPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINS

BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES

IMMUNE SYSTEM|NEURODEGENERATIVE DISEASES|NUCLEOTIDE METABOLISM|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|TRANSCRIPTION|TRANSCRIPTION RELATED PROTEINS|UNPROCESSED

NUCLEOTIDE METABOLISM|SIGNAL TRANSDUCTIONFOLDING, SORTING AND DEGRADATION|NUCLEOTIDE METABOLISM|REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINS|UNPROCESSEDFOLDING, SORTING AND DEGRADATION|NUCLEOTIDE METABOLISM

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BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDSCARBOHYDRATE METABOLISM|LIPID METABOLISM|SIGNAL TRANSDUCTIONMEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES

CARBOHYDRATE METABOLISM|ENERGY METABOLISMCARBOHYDRATE METABOLISM|ENERGY METABOLISM

FOLDING, SORTING AND DEGRADATION|INORGANIC ION TRANSPORT AND METABOLISM|OTHERS|PROTEIN FOLDING AND ASSOCIATED PROCESSING

METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDS

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|GLYCAN BIOSYNTHESIS AND METABOLISM|OTHERS

ENERGY METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISMOTHERS|XENOBIOTICS BIODEGRADATION AND METABOLISMCARBOHYDRATE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMCARBOHYDRATE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|LIPID METABOLISMXENOBIOTICS BIODEGRADATION AND METABOLISMCARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTION|XENOBIOTICS BIODEGRADATION AND METABOLISM

METABOLISM OF OTHER AMINO ACIDS|TRANSLATION

BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITES|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|CELL GROWTH AND DEATH|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|GLYCAN BIOSYNTHESIS AND METABOLISM|IMMUNE SYSTEM|OTHERS|REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINSFOLDING, SORTING AND DEGRADATION|GENERAL FUNCTION PREDICTION ONLY|GLYCAN BIOSYNTHESIS AND METABOLISM|IMMUNE SYSTEM DISEASES|OTHERS|REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINS|SPORULATION|TRANSCRIPTION RELATED PROTEINS|TRANSLATION PROTEINSBIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|CELL DIVISION|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|XENOBIOTICS BIODEGRADATION AND METABOLISMBIOSYNTHESIS OF SECONDARY METABOLITES|OTHERS|XENOBIOTICS BIODEGRADATION AND METABOLISM

CARBOHYDRATE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

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XENOBIOTICS BIODEGRADATION AND METABOLISM

XENOBIOTICS BIODEGRADATION AND METABOLISM

ENDOCRINE SYSTEM|LIPID METABOLISM|NEURODEGENERATIVE DISEASESCIRCULATORY SYSTEM|ENDOCRINE SYSTEM|IMMUNE SYSTEM|LIPID METABOLISM|NERVOUS SYSTEM|SIGNAL TRANSDUCTION

XENOBIOTICS BIODEGRADATION AND METABOLISM

LIPID METABOLISM|SIGNALING MOLECULES AND INTERACTION|TRANSPORT AND CATABOLISM

REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINS

CELL GROWTH AND DEATH|IMMUNE SYSTEM|REPLICATION AND REPAIRREPLICATION, RECOMBINATION AND REPAIR PROTEINSREPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINSREPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINSFOLDING, SORTING AND DEGRADATION|OTHERS|REPLICATION, RECOMBINATION AND REPAIR PROTEINS

FOLDING, SORTING AND DEGRADATION|TRANSLATION PROTEINS

BIOSYNTHESIS OF SECONDARY METABOLITES|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|REPLICATION AND REPAIR|TRANSPORT AND CATABOLISMLIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|TRANSPORT AND CATABOLISM

LIPID METABOLISM|TRANSPORT AND CATABOLISMAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|METABOLISM OF OTHER AMINO ACIDS

REPLICATION, RECOMBINATION AND REPAIR PROTEINSREPLICATION, RECOMBINATION AND REPAIR PROTEINS

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REPLICATION AND REPAIR|TRANSLATION PROTEINS

REPLICATION, RECOMBINATION AND REPAIR PROTEINSIMMUNE SYSTEM DISEASES|OTHERS|TRANSCRIPTION

BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENERGY METABOLISM|ENZYME FAMILIES|GLYCAN BIOSYNTHESIS AND METABOLISM|INFECTIOUS DISEASES|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMSMETABOLISM OF COFACTORS AND VITAMINS|SIGNAL TRANSDUCTION|XENOBIOTICS BIODEGRADATION AND METABOLISM

CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|ENERGY METABOLISM

CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY SYSTEM|DEVELOPMENT|ENDOCRINE SYSTEM|IMMUNE SYSTEM|MEMBRANE TRANSPORT|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|OTHERS|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|SPORULATION|TRANSCRIPTION

METABOLISM OF COFACTORS AND VITAMINS|SIGNAL TRANSDUCTION|XENOBIOTICS BIODEGRADATION AND METABOLISM

BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTIONCARBOHYDRATE METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|SIGNAL TRANSDUCTION MECHANISMSCARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTIONCARBOHYDRATE METABOLISM|ENERGY METABOLISM

XENOBIOTICS BIODEGRADATION AND METABOLISM

CANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|ENDOCRINE SYSTEM|GLYCAN BIOSYNTHESIS AND METABOLISM|IMMUNE SYSTEM|IMMUNE SYSTEM DISEASES|INFECTIOUS DISEASES|METABOLIC DISEASES|NERVOUS SYSTEM|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMS|SIGNALING MOLECULES AND INTERACTIONMETABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISM|SIGNALING MOLECULES AND INTERACTIONCARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTIONCARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTION

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CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM

REPLICATION, RECOMBINATION AND REPAIR PROTEINSLIPID METABOLISM|OTHERS|REPLICATION AND REPAIR|TRANSCRIPTION

CANCERS|CARBOHYDRATE METABOLISM|CELL COMMUNICATION|CIRCULATORY SYSTEM|ENDOCRINE SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|SIGNAL TRANSDUCTIONLIPID METABOLISM|TRANSPORT AND CATABOLISM

CARBOHYDRATE METABOLISM|LIPID METABOLISM|SIGNALING MOLECULES AND INTERACTION

ENDOCRINE SYSTEM|IMMUNE SYSTEM|LIPID METABOLISM|TRANSPORT AND CATABOLISM

INORGANIC ION TRANSPORT AND METABOLISM|TRANSPORT AND CATABOLISM

GLYCAN BIOSYNTHESIS AND METABOLISM|TRANSPORT AND CATABOLISMGLYCAN BIOSYNTHESIS AND METABOLISM|TRANSPORT AND CATABOLISMGLYCAN BIOSYNTHESIS AND METABOLISM|TRANSPORT AND CATABOLISMGLYCAN BIOSYNTHESIS AND METABOLISM|TRANSPORT AND CATABOLISM

LIPID METABOLISM|TRANSPORT AND CATABOLISM

XENOBIOTICS BIODEGRADATION AND METABOLISM

ENZYME FAMILIES|NUCLEOTIDE METABOLISM|PROTEIN FOLDING AND ASSOCIATED PROCESSINGCARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|OTHERS

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CARBOHYDRATE METABOLISM|OTHERS|SIGNAL TRANSDUCTIONGLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|SIGNALING MOLECULES AND INTERACTION|TRANSPORT AND CATABOLISMCARBOHYDRATE METABOLISM|TRANSPORT AND CATABOLISMBIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|METABOLISM OF OTHER AMINO ACIDSCARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|TRANSPORT AND CATABOLISMCARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|TRANSPORT AND CATABOLISMGLYCAN BIOSYNTHESIS AND METABOLISM|TRANSPORT AND CATABOLISMGLYCAN BIOSYNTHESIS AND METABOLISM|TRANSPORT AND CATABOLISM

BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

GLYCAN BIOSYNTHESIS AND METABOLISM|SIGNALING MOLECULES AND INTERACTION

GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|TRANSPORT AND CATABOLISMLIPID METABOLISM|TRANSPORT AND CATABOLISMGLYCAN BIOSYNTHESIS AND METABOLISM|TRANSPORT AND CATABOLISM

CARBOHYDRATE METABOLISM|FOLDING, SORTING AND DEGRADATION|GLYCAN BIOSYNTHESIS AND METABOLISM|TRANSPORT AND CATABOLISM

GLYCAN BIOSYNTHESIS AND METABOLISM|TRANSPORT AND CATABOLISM

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IMMUNE SYSTEM DISEASES|REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINSMETABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISM

REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINS

METABOLISM OF COFACTORS AND VITAMINS|SIGNAL TRANSDUCTION|SIGNALING MOLECULES AND INTERACTION

AMINO ACID METABOLISM|METABOLISM OF OTHER AMINO ACIDSBIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDESLIPID METABOLISM|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|GLYCAN BIOSYNTHESIS AND METABOLISM|INFECTIOUS DISEASES|MEMBRANE TRANSPORT|METABOLISM OF COFACTORS AND VITAMINS|PROTEIN FOLDING AND ASSOCIATED PROCESSING

AMINO ACID METABOLISM|ENZYME FAMILIES|METABOLISM OF OTHER AMINO ACIDS

ENDOCRINE SYSTEM|ENZYME FAMILIES|IMMUNE SYSTEM|METABOLISM OF OTHER AMINO ACIDS|SIGNALING MOLECULES AND INTERACTION

ENZYME FAMILIES|METABOLISM OF OTHER AMINO ACIDS

AMINO ACID METABOLISM|ENZYME FAMILIES|METABOLISM OF OTHER AMINO ACIDSENDOCRINE SYSTEM|ENZYME FAMILIES|SIGNALING MOLECULES AND INTERACTION

ENZYME FAMILIES|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES

AMINO ACID METABOLISM|ENZYME FAMILIES|METABOLISM OF OTHER AMINO ACIDS

ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|TRANSPORT AND CATABOLISMENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION

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ENZYME FAMILIES|SIGNALING MOLECULES AND INTERACTIONENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|TRANSPORT AND CATABOLISMCIRCULATORY DISEASES|ENDOCRINE SYSTEM|ENZYME FAMILIES|SIGNALING MOLECULES AND INTERACTION

ENZYME FAMILIES|GLYCAN BIOSYNTHESIS AND METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULESENDOCRINE SYSTEM|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|TRANSPORT AND CATABOLISM

AMINO ACID METABOLISM|ENDOCRINE SYSTEM|ENZYME FAMILIES

ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|NEURODEGENERATIVE DISEASES

AMINO ACID METABOLISM|CELL COMMUNICATION|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|MEMBRANE TRANSPORT|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|SIGNALING MOLECULES AND INTERACTION

ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|SIGNAL TRANSDUCTIONCELLULAR PROCESSES AND SIGNALING|ENZYME FAMILIES

ENZYME FAMILIES|IMMUNE SYSTEM|SIGNALING MOLECULES AND INTERACTIONENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION

ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION

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ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATIONCELL GROWTH AND DEATH|ENVIRONMENTAL ADAPTATION|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|INFECTIOUS DISEASES|MEMBRANE TRANSPORT|NEURODEGENERATIVE DISEASES|OTHERS|SIGNAL TRANSDUCTION|TRANSPORT AND CATABOLISMENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|TRANSPORT AND CATABOLISM

ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|TRANSPORT AND CATABOLISMENZYME FAMILIES|IMMUNE SYSTEM|TRANSPORT AND CATABOLISMENZYME FAMILIES|IMMUNE SYSTEM|NEURODEGENERATIVE DISEASES

CELL GROWTH AND DEATH|ENZYME FAMILIES|REPLICATION AND REPAIR

ENZYME FAMILIES|SIGNALING MOLECULES AND INTERACTIONCELLULAR PROCESSES AND SIGNALING|ENZYME FAMILIES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|OTHERS|SIGNAL TRANSDUCTION|TRANSPORT AND CATABOLISM

ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATIONCELL MOTILITY|ENZYME FAMILIES|MEMBRANE TRANSPORT|OTHERSENZYME FAMILIES|NEURODEGENERATIVE DISEASES

CELLULAR PROCESSES AND SIGNALING|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|OTHERS|SIGNALING MOLECULES AND INTERACTIONENDOCRINE SYSTEM|ENZYME FAMILIES|IMMUNE SYSTEM|NEURODEGENERATIVE DISEASES|SIGNALING MOLECULES AND INTERACTION

ENZYME FAMILIES|SIGNALING MOLECULES AND INTERACTION

ENZYME FAMILIES|NEURODEGENERATIVE DISEASES

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ENZYME FAMILIES|SIGNALING MOLECULES AND INTERACTION

CELLULAR PROCESSES AND SIGNALING|ENZYME FAMILIES

ENZYME FAMILIES|INFECTIOUS DISEASES|NEURODEGENERATIVE DISEASES|SIGNALING MOLECULES AND INTERACTION

ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATIONENZYME FAMILIES|GLYCAN BIOSYNTHESIS AND METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|MEMBRANE TRANSPORTCARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|OTHERS|TRANSCRIPTIONAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDS|REPLICATION AND REPAIRAMINO ACID METABOLISM|ENERGY METABOLISM|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDSCARBOHYDRATE METABOLISM|METABOLISM OF COFACTORS AND VITAMINSBIOSYNTHESIS OF SECONDARY METABOLITES|ENZYME FAMILIES

AMINO ACID METABOLISM|ENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDSLIPID METABOLISM|TRANSPORT AND CATABOLISM

GLYCAN BIOSYNTHESIS AND METABOLISM|TRANSPORT AND CATABOLISMMEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|REPLICATION AND REPAIR

AMINO ACID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|XENOBIOTICS BIODEGRADATION AND METABOLISM

CARBOHYDRATE METABOLISM|ENERGY METABOLISMAMINO ACID METABOLISM|INFECTIOUS DISEASES|NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

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CANCERS|CELL GROWTH AND DEATH|NEURODEGENERATIVE DISEASES|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION

METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDS|NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMAMINO ACID METABOLISM|ENZYME FAMILIES|NUCLEOTIDE METABOLISM

BIOSYNTHESIS OF SECONDARY METABOLITES|SIGNAL TRANSDUCTION

IMMUNE SYSTEM|NUCLEOTIDE METABOLISM|TRANSCRIPTION|XENOBIOTICS BIODEGRADATION AND METABOLISMAMINO ACID METABOLISM|NUCLEOTIDE METABOLISMMETABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISMMEMBRANE TRANSPORT|NUCLEOTIDE METABOLISM

ENERGY METABOLISM|METABOLISM OF COFACTORS AND VITAMINS

IMMUNE SYSTEM DISEASES|NUCLEOTIDE METABOLISMIMMUNE SYSTEM|IMMUNE SYSTEM DISEASES|NUCLEOTIDE METABOLISM|SIGNALING MOLECULES AND INTERACTION|XENOBIOTICS BIODEGRADATION AND METABOLISM

CARBOHYDRATE METABOLISM|METABOLISM OF COFACTORS AND VITAMINS

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AMINO ACID METABOLISM|ENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDS|XENOBIOTICS BIODEGRADATION AND METABOLISM

METABOLISM OF COFACTORS AND VITAMINS|TRANSCRIPTIONXENOBIOTICS BIODEGRADATION AND METABOLISMXENOBIOTICS BIODEGRADATION AND METABOLISM

FOLDING, SORTING AND DEGRADATION|GENERAL FUNCTION PREDICTION ONLY|GLYCAN BIOSYNTHESIS AND METABOLISM|IMMUNE SYSTEM|NUCLEOTIDE METABOLISM|OTHERS|REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINS|TRANSCRIPTION|TRANSLATION|TRANSLATION PROTEINS|TRANSPORT AND CATABOLISM

METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISM

NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMMETABOLISM OF COFACTORS AND VITAMINS|TRANSPORT AND CATABOLISMNUCLEOTIDE METABOLISM|REPLICATION AND REPAIR

METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISM|OTHERSNUCLEOTIDE METABOLISM|SIGNALING MOLECULES AND INTERACTION

NUCLEOTIDE METABOLISM|TRANSPORT AND CATABOLISMCARBOHYDRATE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMCARBOHYDRATE METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISM|SIGNALING MOLECULES AND INTERACTIONENERGY METABOLISM|MEMBRANE TRANSPORT|OTHERS

CELL MOTILITY|ENERGY METABOLISM|FOLDING, SORTING AND DEGRADATION|INFECTIOUS DISEASES|MEMBRANE TRANSPORT|NEURODEGENERATIVE DISEASES|TRANSPORT AND CATABOLISM

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ENERGY METABOLISM|NEURODEGENERATIVE DISEASES|SIGNAL TRANSDUCTION

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMAMINO ACID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

XENOBIOTICS BIODEGRADATION AND METABOLISM

XENOBIOTICS BIODEGRADATION AND METABOLISMXENOBIOTICS BIODEGRADATION AND METABOLISMXENOBIOTICS BIODEGRADATION AND METABOLISMBIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|ENERGY METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERSCARBOHYDRATE METABOLISM|OTHERS|TRANSPORT AND CATABOLISMAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDS

AMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|METABOLIC DISEASES|METABOLISM OF OTHER AMINO ACIDSAMINO ACID METABOLISM|METABOLISM OF OTHER AMINO ACIDSAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES

NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITESAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITESAMINO ACID METABOLISM|CARBOHYDRATE METABOLISMCARBOHYDRATE METABOLISM|ENERGY METABOLISM

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CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM

CARBOHYDRATE METABOLISM|ENERGY METABOLISM

XENOBIOTICS BIODEGRADATION AND METABOLISM

CARBOHYDRATE METABOLISM|ENERGY METABOLISM

XENOBIOTICS BIODEGRADATION AND METABOLISMCARBOHYDRATE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

CARBOHYDRATE METABOLISM|METABOLISM OF OTHER AMINO ACIDS|TRANSPORT AND CATABOLISMAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|ENZYME FAMILIES|LIPID METABOLISM|OTHERS|XENOBIOTICS BIODEGRADATION AND METABOLISMCARBOHYDRATE METABOLISM|ENERGY METABOLISMAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM

CARBOHYDRATE METABOLISM|ENERGY METABOLISM

CARBOHYDRATE METABOLISM|ENERGY METABOLISMAMINO ACID METABOLISM|BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|CARBOHYDRATE METABOLISM

AMINO ACID METABOLISM|CARBOHYDRATE METABOLISMCARBOHYDRATE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

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AMINO ACID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|LIPID METABOLISM|TRANSPORT AND CATABOLISM

CARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTIONMETABOLISM OF COFACTORS AND VITAMINS|REPLICATION, RECOMBINATION AND REPAIR PROTEINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|XENOBIOTICS BIODEGRADATION AND METABOLISM

CARBOHYDRATE METABOLISM|FOLDING, SORTING AND DEGRADATION

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

CANCERS|CARBOHYDRATE METABOLISM|ENERGY METABOLISM

AMINO ACID METABOLISM|METABOLISM OF OTHER AMINO ACIDS

CARBOHYDRATE METABOLISM|ENERGY METABOLISM

AMINO ACID METABOLISM|CARBOHYDRATE METABOLISMAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM

BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|BIOSYNTHESIS OF SECONDARY METABOLITES

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AMINO ACID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMAMINO ACID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS

AMINO ACID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS

REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINS

CARBOHYDRATE METABOLISM|ENERGY METABOLISM

AMINO ACID METABOLISM|NUCLEOTIDE METABOLISMAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITESAMINO ACID METABOLISM|ENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDSAMINO ACID METABOLISM|METABOLISM OF OTHER AMINO ACIDS

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METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDS

CARBOHYDRATE METABOLISM|SIGNAL TRANSDUCTIONAMINO ACID METABOLISM|ENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDS

CELL COMMUNICATION|CELL GROWTH AND DEATH|CIRCULATORY DISEASES|CIRCULATORY SYSTEM|ENDOCRINE SYSTEM|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|NERVOUS SYSTEM|NUCLEOTIDE METABOLISM|SENSORY SYSTEM|SIGNAL TRANSDUCTION|SIGNALING MOLECULES AND INTERACTION

CELL COMMUNICATION|CIRCULATORY SYSTEM|NERVOUS SYSTEM|NUCLEOTIDE METABOLISM

BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|MEMBRANE TRANSPORT|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|TRANSLATION PROTEINS

XENOBIOTICS BIODEGRADATION AND METABOLISMAMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|XENOBIOTICS BIODEGRADATION AND METABOLISMBIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|CARBOHYDRATE METABOLISM|FUNCTION UNKNOWN|OTHERSCARBOHYDRATE METABOLISM|ENERGY METABOLISM

BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|BIOSYNTHESIS OF SECONDARY METABOLITESCARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM

AMINO ACID METABOLISM|CARBOHYDRATE METABOLISMLIPID METABOLISM|TRANSPORT AND CATABOLISMAMINO ACID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMFOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|NEURODEGENERATIVE DISEASES|PROTEIN FOLDING AND ASSOCIATED PROCESSING|SIGNAL TRANSDUCTION|TRANSCRIPTIONBIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|CARBOHYDRATE METABOLISMCARBOHYDRATE METABOLISM|ENERGY METABOLISM

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MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES

CARBOHYDRATE METABOLISM|ENERGY METABOLISM

CARBOHYDRATE METABOLISM|ENERGY METABOLISM

XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|OTHERS|TRANSPORT AND CATABOLISM

AMINO ACID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMFOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|INFECTIOUS DISEASES|MEMBRANE TRANSPORT|PROTEIN FOLDING AND ASSOCIATED PROCESSING

BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM

CARBOHYDRATE METABOLISM|NUCLEOTIDE METABOLISM

BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|METABOLISM OF COFACTORS AND VITAMINSGLYCAN BIOSYNTHESIS AND METABOLISM|OTHERS|REPLICATION AND REPAIR

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AMINO ACID METABOLISM|CARBOHYDRATE METABOLISM

MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES

BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISMXENOBIOTICS BIODEGRADATION AND METABOLISM

GLYCAN BIOSYNTHESIS AND METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|METABOLISM OF COFACTORS AND VITAMINS|OTHERS

METABOLISM OF OTHER AMINO ACIDS|TRANSLATION

METABOLISM OF COFACTORS AND VITAMINS|TRANSLATION

BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|LIPID METABOLISM|OTHERS|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMCARBOHYDRATE METABOLISM|ENERGY METABOLISM|LIPID METABOLISMBIOSYNTHESIS OF SECONDARY METABOLITES|METABOLISM OF COFACTORS AND VITAMINSCARBOHYDRATE METABOLISM|LIPID METABOLISMCARBOHYDRATE METABOLISM|LIPID METABOLISMCARBOHYDRATE METABOLISM|LIPID METABOLISM

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ENDOCRINE SYSTEM|LIPID METABOLISM|TRANSPORT AND CATABOLISM

CARBOHYDRATE METABOLISM|ENERGY METABOLISM

AMINO ACID METABOLISM|ENERGY METABOLISM|METABOLISM OF OTHER AMINO ACIDS

AMINO ACID METABOLISM|ENERGY METABOLISM|SIGNAL TRANSDUCTIONENERGY METABOLISM|METABOLISM OF COFACTORS AND VITAMINS

BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|ENVIRONMENTAL ADAPTATION|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|TRANSCRIPTIONMETABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDSAMINO ACID METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISMAMINO ACID METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM

CANCERS|CELL GROWTH AND DEATH|ENDOCRINE SYSTEM|ENZYME FAMILIES|EXCRETORY SYSTEM|FOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|NEURODEGENERATIVE DISEASES|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|TRANSCRIPTION|TRANSPORT AND CATABOLISM

GLYCAN BIOSYNTHESIS AND METABOLISM|METABOLISM OF OTHER AMINO ACIDS

GLYCAN BIOSYNTHESIS AND METABOLISM|METABOLISM OF OTHER AMINO ACIDSGLYCAN BIOSYNTHESIS AND METABOLISM|METABOLISM OF OTHER AMINO ACIDSMETABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISM

NUCLEOTIDE METABOLISM|OTHERS|TRANSLATION PROTEINS

METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISM

METABOLISM OF COFACTORS AND VITAMINS|TRANSCRIPTION

CARBOHYDRATE METABOLISM|METABOLISM OF COFACTORS AND VITAMINSAMINO ACID METABOLISM|NUCLEOTIDE METABOLISM

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ENZYME FAMILIES|NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|ENERGY METABOLISM|ENZYME FAMILIESAMINO ACID METABOLISM|ENZYME FAMILIES|NUCLEOTIDE METABOLISM

XENOBIOTICS BIODEGRADATION AND METABOLISM

BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|LIPID METABOLISMAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM

BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITES

REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINS

METABOLISM OF COFACTORS AND VITAMINS|OTHERSMETABOLISM OF COFACTORS AND VITAMINS|OTHERS

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BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|CELL GROWTH AND DEATH|ELECTRON TRANSFER CARRIERS|ENERGY METABOLISM|GENERAL FUNCTION PREDICTION ONLY|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|REPLICATION AND REPAIR|TRANSLATION PROTEINS|XENOBIOTICS BIODEGRADATION AND METABOLISMBIOSYNTHESIS OF SECONDARY METABOLITES|ENERGY METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISMAMINO ACID METABOLISM|BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|XENOBIOTICS BIODEGRADATION AND METABOLISMAMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|ENERGY METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

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AMINO ACID METABOLISM|CARBOHYDRATE METABOLISM|ENERGY METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|NEURODEGENERATIVE DISEASES|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

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AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|ENERGY METABOLISM|ENZYME FAMILIES|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CANCERS|GLYCAN BIOSYNTHESIS AND METABOLISM|OTHERS|REPLICATION AND REPAIR|TRANSCRIPTION

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|ENERGY METABOLISM|ENZYME FAMILIES|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|CANCERS|ENVIRONMENTAL ADAPTATION|INFECTIOUS DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|SIGNAL TRANSDUCTION|TRANSPORT AND CATABOLISM

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|ENZYME FAMILIES|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

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BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITES|BIOSYNTHESIS OF SECONDARY METABOLITES|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|ENERGY METABOLISM|OTHERS|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|XENOBIOTICS BIODEGRADATION AND METABOLISM

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AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|LIPID METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDS|NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

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AMINO ACID METABOLISM|BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITES|BIOSYNTHESIS OF SECONDARY METABOLITES|LIPID METABOLISM|OTHERS|XENOBIOTICS BIODEGRADATION AND METABOLISM

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AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CELL MOTILITY|ENZYME FAMILIES|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|MEMBRANE TRANSPORT|METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDS|REPLICATION AND REPAIR|TRANSCRIPTION|TRANSLATION PROTEINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

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AMINO ACID METABOLISM|BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GENERAL FUNCTION PREDICTION ONLY|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|MEMBRANE TRANSPORT|OTHERS|PROTEIN FOLDING AND ASSOCIATED PROCESSING|REPLICATION AND REPAIR|TRANSLATION PROTEINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

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CANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|ENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|OTHERS|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|TRANSCRIPTION

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|LIPID METABOLISM|SIGNAL TRANSDUCTION|XENOBIOTICS BIODEGRADATION AND METABOLISM

BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|CELLULAR PROCESSES AND SIGNALING|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|SIGNALING MOLECULES AND INTERACTION

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CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

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AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|GLYCAN BIOSYNTHESIS AND METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISM|OTHERS|SIGNALING MOLECULES AND INTERACTION|TRANSLATION PROTEINS

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AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|SIGNAL TRANSDUCTION

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CARBOHYDRATE METABOLISM|FUNCTION UNKNOWN|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|SIGNAL TRANSDUCTION MECHANISMS|TRANSLATION PROTEINS

CANCERS|CARBOHYDRATE METABOLISM|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|ENDOCRINE SYSTEM|EXCRETORY SYSTEM|IMMUNE SYSTEM|METABOLIC DISEASES|NERVOUS SYSTEM|SIGNAL TRANSDUCTION

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CANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|DEVELOPMENT|ENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|ENZYME FAMILIES|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|METABOLIC DISEASES|NERVOUS SYSTEM|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMS|SIGNALING MOLECULES AND INTERACTION|TRANSPORT AND CATABOLISMCANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY DISEASES|DEVELOPMENT|ENDOCRINE SYSTEM|ENZYME FAMILIES|IMMUNE SYSTEM|IMMUNE SYSTEM DISEASES|INFECTIOUS DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMS|SIGNALING MOLECULES AND INTERACTION|TRANSPORT AND CATABOLISMCELL GROWTH AND DEATH|ENZYME FAMILIES|MEMBRANE TRANSPORT|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMSCANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY DISEASES|CIRCULATORY SYSTEM|DEVELOPMENT|ENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|ENZYME FAMILIES|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|MEMBRANE TRANSPORT|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMS|SIGNALING MOLECULES AND INTERACTION|SPORULATION|TRANSCRIPTION|TRANSPORT AND CATABOLISMCANCERS|CELL GROWTH AND DEATH|ENDOCRINE SYSTEM|ENZYME FAMILIES|IMMUNE SYSTEM|INFECTIOUS DISEASES|METABOLIC DISEASES|NERVOUS SYSTEM|SIGNAL TRANSDUCTIONCELL COMMUNICATION|CELL GROWTH AND DEATH|CIRCULATORY DISEASES|CIRCULATORY SYSTEM|ENDOCRINE SYSTEM|ENZYME FAMILIES|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|SENSORY SYSTEM|SIGNAL TRANSDUCTION|TRANSPORT AND CATABOLISM

CANCERS|CELL COMMUNICATION|CIRCULATORY SYSTEM|ENDOCRINE SYSTEM|ENZYME FAMILIES|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|NERVOUS SYSTEM|SIGNAL TRANSDUCTION|TRANSPORT AND CATABOLISM

CANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|DEVELOPMENT|ENDOCRINE SYSTEM|ENZYME FAMILIES|IMMUNE SYSTEM|NEURODEGENERATIVE DISEASES|REPLICATION AND REPAIR|TRANSCRIPTIONCANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY SYSTEM|DEVELOPMENT|ENDOCRINE SYSTEM|ENZYME FAMILIES|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|METABOLIC DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|SIGNALING MOLECULES AND INTERACTIONCELL COMMUNICATION|CELL GROWTH AND DEATH|ENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|INFECTIOUS DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|SIGNAL TRANSDUCTION

CANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY SYSTEM|DEVELOPMENT|ENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|ENZYME FAMILIES|IMMUNE SYSTEM|INFECTIOUS DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|SIGNAL TRANSDUCTION

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BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|CARBOHYDRATE METABOLISM|FOLDING, SORTING AND DEGRADATION|GLYCAN BIOSYNTHESIS AND METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISM|OTHERS|REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINS|UNPROCESSED

IMMUNE SYSTEM|NEURODEGENERATIVE DISEASES|NUCLEOTIDE METABOLISM|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|TRANSCRIPTION|TRANSCRIPTION RELATED PROTEINS|UNPROCESSED

FOLDING, SORTING AND DEGRADATION|NUCLEOTIDE METABOLISM|REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINS|UNPROCESSED

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BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDS

BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITES|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|CELL GROWTH AND DEATH|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|GLYCAN BIOSYNTHESIS AND METABOLISM|IMMUNE SYSTEM|OTHERS|REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINSFOLDING, SORTING AND DEGRADATION|GENERAL FUNCTION PREDICTION ONLY|GLYCAN BIOSYNTHESIS AND METABOLISM|IMMUNE SYSTEM DISEASES|OTHERS|REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINS|SPORULATION|TRANSCRIPTION RELATED PROTEINS|TRANSLATION PROTEINSBIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|CELL DIVISION|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|XENOBIOTICS BIODEGRADATION AND METABOLISM

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BIOSYNTHESIS OF SECONDARY METABOLITES|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

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BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENERGY METABOLISM|ENZYME FAMILIES|GLYCAN BIOSYNTHESIS AND METABOLISM|INFECTIOUS DISEASES|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMS

CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY SYSTEM|DEVELOPMENT|ENDOCRINE SYSTEM|IMMUNE SYSTEM|MEMBRANE TRANSPORT|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|OTHERS|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|SPORULATION|TRANSCRIPTION

CANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|ENDOCRINE SYSTEM|GLYCAN BIOSYNTHESIS AND METABOLISM|IMMUNE SYSTEM|IMMUNE SYSTEM DISEASES|INFECTIOUS DISEASES|METABOLIC DISEASES|NERVOUS SYSTEM|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMS|SIGNALING MOLECULES AND INTERACTION

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CANCERS|CARBOHYDRATE METABOLISM|CELL COMMUNICATION|CIRCULATORY SYSTEM|ENDOCRINE SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|SIGNAL TRANSDUCTION

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BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

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AMINO ACID METABOLISM|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|GLYCAN BIOSYNTHESIS AND METABOLISM|INFECTIOUS DISEASES|MEMBRANE TRANSPORT|METABOLISM OF COFACTORS AND VITAMINS|PROTEIN FOLDING AND ASSOCIATED PROCESSING

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AMINO ACID METABOLISM|CELL COMMUNICATION|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|MEMBRANE TRANSPORT|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|SIGNALING MOLECULES AND INTERACTION

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CELL GROWTH AND DEATH|ENVIRONMENTAL ADAPTATION|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|INFECTIOUS DISEASES|MEMBRANE TRANSPORT|NEURODEGENERATIVE DISEASES|OTHERS|SIGNAL TRANSDUCTION|TRANSPORT AND CATABOLISM

CELLULAR PROCESSES AND SIGNALING|ENZYME FAMILIES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|OTHERS|SIGNAL TRANSDUCTION|TRANSPORT AND CATABOLISM

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AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDS|REPLICATION AND REPAIR

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METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDS|NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

IMMUNE SYSTEM|IMMUNE SYSTEM DISEASES|NUCLEOTIDE METABOLISM|SIGNALING MOLECULES AND INTERACTION|XENOBIOTICS BIODEGRADATION AND METABOLISM

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FOLDING, SORTING AND DEGRADATION|GENERAL FUNCTION PREDICTION ONLY|GLYCAN BIOSYNTHESIS AND METABOLISM|IMMUNE SYSTEM|NUCLEOTIDE METABOLISM|OTHERS|REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINS|TRANSCRIPTION|TRANSLATION|TRANSLATION PROTEINS|TRANSPORT AND CATABOLISM

CELL MOTILITY|ENERGY METABOLISM|FOLDING, SORTING AND DEGRADATION|INFECTIOUS DISEASES|MEMBRANE TRANSPORT|NEURODEGENERATIVE DISEASES|TRANSPORT AND CATABOLISM

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AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

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AMINO ACID METABOLISM|BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

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CELL COMMUNICATION|CELL GROWTH AND DEATH|CIRCULATORY DISEASES|CIRCULATORY SYSTEM|ENDOCRINE SYSTEM|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|NERVOUS SYSTEM|NUCLEOTIDE METABOLISM|SENSORY SYSTEM|SIGNAL TRANSDUCTION|SIGNALING MOLECULES AND INTERACTION

BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|MEMBRANE TRANSPORT|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|TRANSLATION PROTEINS

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|XENOBIOTICS BIODEGRADATION AND METABOLISM

FOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|NEURODEGENERATIVE DISEASES|PROTEIN FOLDING AND ASSOCIATED PROCESSING|SIGNAL TRANSDUCTION|TRANSCRIPTION

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AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

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BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|LIPID METABOLISM|OTHERS|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

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BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|ENVIRONMENTAL ADAPTATION|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|TRANSCRIPTION

CANCERS|CELL GROWTH AND DEATH|ENDOCRINE SYSTEM|ENZYME FAMILIES|EXCRETORY SYSTEM|FOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|NEURODEGENERATIVE DISEASES|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|TRANSCRIPTION|TRANSPORT AND CATABOLISM

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BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|CELL GROWTH AND DEATH|ELECTRON TRANSFER CARRIERS|ENERGY METABOLISM|GENERAL FUNCTION PREDICTION ONLY|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|REPLICATION AND REPAIR|TRANSLATION PROTEINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|XENOBIOTICS BIODEGRADATION AND METABOLISM

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AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|NEURODEGENERATIVE DISEASES|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

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AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CELL MOTILITY|ENZYME FAMILIES|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|MEMBRANE TRANSPORT|METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDS|REPLICATION AND REPAIR|TRANSCRIPTION|TRANSLATION PROTEINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

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AMINO ACID METABOLISM|BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GENERAL FUNCTION PREDICTION ONLY|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|MEMBRANE TRANSPORT|OTHERS|PROTEIN FOLDING AND ASSOCIATED PROCESSING|REPLICATION AND REPAIR|TRANSLATION PROTEINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

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BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|CELLULAR PROCESSES AND SIGNALING|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|SIGNALING MOLECULES AND INTERACTION

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CANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|DEVELOPMENT|ENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|ENZYME FAMILIES|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|METABOLIC DISEASES|NERVOUS SYSTEM|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMS|SIGNALING MOLECULES AND INTERACTION|TRANSPORT AND CATABOLISMCANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY DISEASES|DEVELOPMENT|ENDOCRINE SYSTEM|ENZYME FAMILIES|IMMUNE SYSTEM|IMMUNE SYSTEM DISEASES|INFECTIOUS DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMS|SIGNALING MOLECULES AND INTERACTION|TRANSPORT AND CATABOLISM

CANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY DISEASES|CIRCULATORY SYSTEM|DEVELOPMENT|ENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|ENZYME FAMILIES|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|MEMBRANE TRANSPORT|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMS|SIGNALING MOLECULES AND INTERACTION|SPORULATION|TRANSCRIPTION|TRANSPORT AND CATABOLISM

CELL COMMUNICATION|CELL GROWTH AND DEATH|CIRCULATORY DISEASES|CIRCULATORY SYSTEM|ENDOCRINE SYSTEM|ENZYME FAMILIES|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|SENSORY SYSTEM|SIGNAL TRANSDUCTION|TRANSPORT AND CATABOLISM

CANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY SYSTEM|DEVELOPMENT|ENDOCRINE SYSTEM|ENZYME FAMILIES|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|METABOLIC DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|SIGNALING MOLECULES AND INTERACTIONCELL COMMUNICATION|CELL GROWTH AND DEATH|ENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|INFECTIOUS DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|SIGNAL TRANSDUCTION

CANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY SYSTEM|DEVELOPMENT|ENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|ENZYME FAMILIES|IMMUNE SYSTEM|INFECTIOUS DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|SIGNAL TRANSDUCTION

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BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|CARBOHYDRATE METABOLISM|FOLDING, SORTING AND DEGRADATION|GLYCAN BIOSYNTHESIS AND METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|NUCLEOTIDE METABOLISM|OTHERS|REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINS|UNPROCESSED

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BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDS

BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITES|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|CELL GROWTH AND DEATH|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|GLYCAN BIOSYNTHESIS AND METABOLISM|IMMUNE SYSTEM|OTHERS|REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINSFOLDING, SORTING AND DEGRADATION|GENERAL FUNCTION PREDICTION ONLY|GLYCAN BIOSYNTHESIS AND METABOLISM|IMMUNE SYSTEM DISEASES|OTHERS|REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINS|SPORULATION|TRANSCRIPTION RELATED PROTEINS|TRANSLATION PROTEINS

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BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENERGY METABOLISM|ENZYME FAMILIES|GLYCAN BIOSYNTHESIS AND METABOLISM|INFECTIOUS DISEASES|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMS

CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY SYSTEM|DEVELOPMENT|ENDOCRINE SYSTEM|IMMUNE SYSTEM|MEMBRANE TRANSPORT|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|OTHERS|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|SPORULATION|TRANSCRIPTION

CANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|ENDOCRINE SYSTEM|GLYCAN BIOSYNTHESIS AND METABOLISM|IMMUNE SYSTEM|IMMUNE SYSTEM DISEASES|INFECTIOUS DISEASES|METABOLIC DISEASES|NERVOUS SYSTEM|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMS|SIGNALING MOLECULES AND INTERACTION

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AMINO ACID METABOLISM|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|GLYCAN BIOSYNTHESIS AND METABOLISM|INFECTIOUS DISEASES|MEMBRANE TRANSPORT|METABOLISM OF COFACTORS AND VITAMINS|PROTEIN FOLDING AND ASSOCIATED PROCESSING

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CELL GROWTH AND DEATH|ENVIRONMENTAL ADAPTATION|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|INFECTIOUS DISEASES|MEMBRANE TRANSPORT|NEURODEGENERATIVE DISEASES|OTHERS|SIGNAL TRANSDUCTION|TRANSPORT AND CATABOLISM

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AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDS|REPLICATION AND REPAIR

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FOLDING, SORTING AND DEGRADATION|GENERAL FUNCTION PREDICTION ONLY|GLYCAN BIOSYNTHESIS AND METABOLISM|IMMUNE SYSTEM|NUCLEOTIDE METABOLISM|OTHERS|REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINS|TRANSCRIPTION|TRANSLATION|TRANSLATION PROTEINS|TRANSPORT AND CATABOLISM

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AMINO ACID METABOLISM|BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|XENOBIOTICS BIODEGRADATION AND METABOLISM

AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

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CELL COMMUNICATION|CELL GROWTH AND DEATH|CIRCULATORY DISEASES|CIRCULATORY SYSTEM|ENDOCRINE SYSTEM|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|NERVOUS SYSTEM|NUCLEOTIDE METABOLISM|SENSORY SYSTEM|SIGNAL TRANSDUCTION|SIGNALING MOLECULES AND INTERACTION

BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|MEMBRANE TRANSPORT|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|TRANSLATION PROTEINS

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AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|ENDOCRINE SYSTEM|LIPID METABOLISM|METABOLISM OF OTHER AMINO ACIDS|TRANSPORT AND CATABOLISM|XENOBIOTICS BIODEGRADATION AND METABOLISM

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CANCERS|CELL GROWTH AND DEATH|ENDOCRINE SYSTEM|ENZYME FAMILIES|EXCRETORY SYSTEM|FOLDING, SORTING AND DEGRADATION|IMMUNE SYSTEM|NEURODEGENERATIVE DISEASES|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|TRANSCRIPTION|TRANSPORT AND CATABOLISM

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BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|CELL GROWTH AND DEATH|ELECTRON TRANSFER CARRIERS|ENERGY METABOLISM|GENERAL FUNCTION PREDICTION ONLY|LIPID METABOLISM|METABOLISM OF COFACTORS AND VITAMINS|OTHERS|REPLICATION AND REPAIR|TRANSLATION PROTEINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

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AMINO ACID METABOLISM|BIOSYNTHESIS OF SECONDARY METABOLITES|CELL MOTILITY|ENZYME FAMILIES|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|MEMBRANE TRANSPORT|METABOLISM OF COFACTORS AND VITAMINS|METABOLISM OF OTHER AMINO ACIDS|REPLICATION AND REPAIR|TRANSCRIPTION|TRANSLATION PROTEINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

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AMINO ACID METABOLISM|BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GENERAL FUNCTION PREDICTION ONLY|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|MEMBRANE TRANSPORT|OTHERS|PROTEIN FOLDING AND ASSOCIATED PROCESSING|REPLICATION AND REPAIR|TRANSLATION PROTEINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

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CANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|DEVELOPMENT|ENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|ENZYME FAMILIES|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|METABOLIC DISEASES|NERVOUS SYSTEM|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMS|SIGNALING MOLECULES AND INTERACTION|TRANSPORT AND CATABOLISMCANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY DISEASES|DEVELOPMENT|ENDOCRINE SYSTEM|ENZYME FAMILIES|IMMUNE SYSTEM|IMMUNE SYSTEM DISEASES|INFECTIOUS DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMS|SIGNALING MOLECULES AND INTERACTION|TRANSPORT AND CATABOLISM

CANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY DISEASES|CIRCULATORY SYSTEM|DEVELOPMENT|ENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|ENZYME FAMILIES|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|MEMBRANE TRANSPORT|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMS|SIGNALING MOLECULES AND INTERACTION|SPORULATION|TRANSCRIPTION|TRANSPORT AND CATABOLISM

CANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY SYSTEM|DEVELOPMENT|ENDOCRINE SYSTEM|ENZYME FAMILIES|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|METABOLIC DISEASES|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|SIGNALING MOLECULES AND INTERACTION

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BIOSYNTHESIS AND BIODEGRADATION OF SECONDARY METABOLITES|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|CELL GROWTH AND DEATH|ENZYME FAMILIES|FOLDING, SORTING AND DEGRADATION|GLYCAN BIOSYNTHESIS AND METABOLISM|IMMUNE SYSTEM|OTHERS|REPLICATION AND REPAIR|REPLICATION, RECOMBINATION AND REPAIR PROTEINS

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AMINO ACID METABOLISM|BIOSYNTHESIS OF POLYKETIDES AND NONRIBOSOMAL PEPTIDES|BIOSYNTHESIS OF SECONDARY METABOLITES|CARBOHYDRATE METABOLISM|GENERAL FUNCTION PREDICTION ONLY|GLYCAN BIOSYNTHESIS AND METABOLISM|LIPID METABOLISM|MEMBRANE AND INTRACELLULAR STRUCTURAL MOLECULES|MEMBRANE TRANSPORT|OTHERS|PROTEIN FOLDING AND ASSOCIATED PROCESSING|REPLICATION AND REPAIR|TRANSLATION PROTEINS|XENOBIOTICS BIODEGRADATION AND METABOLISM

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CANCERS|CELL COMMUNICATION|CELL GROWTH AND DEATH|CELL MOTILITY|CIRCULATORY DISEASES|CIRCULATORY SYSTEM|DEVELOPMENT|ENDOCRINE SYSTEM|ENVIRONMENTAL ADAPTATION|ENZYME FAMILIES|EXCRETORY SYSTEM|IMMUNE SYSTEM|INFECTIOUS DISEASES|MEMBRANE TRANSPORT|NERVOUS SYSTEM|NEURODEGENERATIVE DISEASES|REPLICATION AND REPAIR|SIGNAL TRANSDUCTION|SIGNAL TRANSDUCTION MECHANISMS|SIGNALING MOLECULES AND INTERACTION|SPORULATION|TRANSCRIPTION|TRANSPORT AND CATABOLISM

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Table S14. Primers and amplification conditions used for quantitative PCR assays of FMP consortium strains in fecal DNA.

A. Primers used to assay human fecal samples.

Bacterial target

Bacteria (universal)

B. Primers used to assay mouse fecal samples.

Bacterial target

Bacteria (universal)

C. Amplification conditions.

i) 94°C for 5 min (1 cycle)ii) 94°C for 20 sec => 64°/63°/60°/55°C† for 20 sec => 72°C for 50 sec (40 cycles)iii) 95°C for 15 sec => 60°C for 15 sec => 95°C for 15 sec (1 cycle)

Genus Bifidobacterium Bifidobacterium animalis subsp. lactis (CNCM I-2494)Lactobacillus delbrueckii subsp. bulgaricus (CNCM I-1632)

Lactobacillus delbrueckii subsp. bulgaricus (CNCM I-1519)

Genus Bifidobacterium Lactobacillus delbrueckii subsp. bulgaricus (CNCM I-1632, CNCM I-1519)

Lactococcus lactis subsp. cremoris (CNCM I-1631)Streptococcus thermophilus (CNCM I-1630)

† = melting temperature (Tm) used corresponds to Tm from tables above

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Table S14. Primers and amplification conditions used for quantitative PCR assays of FMP consortium strains in fecal DNA.

Forward primer name Forward primer sequence Reverse primer name

Bacter_1369 (OFF 2319) CGGTGAATACGTTCCCGG Bacter_1492 (OFF 2320)g-Bifid153-F CTCCTGGAAACGGGTGG g-Bifid699-R OFF2175 GGCGCAGGGAGGAGAC OFF2176OFF2396 TGGCGGCTGAAAGACAT OFF2397

OFF2480 AGCTGGTAGCAGAGCGACATAAGC OFF2481

Forward primer name Forward primer sequence Reverse primer name

k-univN (OFF 2465)TCCTACGGGAGGCAGCAGT

OFF 2466

g-Bifid153-F CTCCTGGAAACGGGTGG g-Bifid699-R OFF 0844 (Ldel01)

ACATGAATCGCATGATTCAAGOFF 0845 (Ldel02)

OFF 2508 AGCAGTAGGGAATCTTCGGCA OFF 2509OFF 2510 TTATTTGAAAGGGGCAATTGCT OFF 2511

ii) 94°C for 20 sec => 64°/63°/60°/55°C† for 20 sec => 72°C for 50 sec (40 cycles)

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Reverse primer sequence Strain used to generate standard curve

TACGGCTACCTTGTTACGACTTGGTGTTCTTCCCGATATCTACAGGCGCGAGCAGTATCACTTAGCTGCTAGCTCTCTAATT

ACCACCGAAACACTGACAGC

Reverse primer sequence Strain used to generate standard curve

GGACTACCAGGGTATCTAATCCTGTTGGTGTTCTTCCCGATATCTACA

AACTCGGCTACGCATCATTGGGGTAGTTACCGTCACTTGATGAGGTGAACTTTCCACTCTCACAC

Bifidobacterium longum (ATCC 15707T)Bifidobacterium longum (ATCC 15707T)Bifidobacterium animalis subsp. lactis (CNCM I-2494)Lactobacillus delbrueckii subsp. bulgaricus (CNCM I-1632)

Lactobacillus delbrueckii subsp. bulgaricus (CNCM I-1519)

Bifidobacterium longum (ATCC 15707T)

Bifidobacterium longum (ATCC 15707T)Lactobacillus delbrueckii subsp. bulgaricus (CNCM I-1632)

Lactococcus lactis subsp. cremoris (CNCM I-1631)Streptococcus thermophilus (CNCM I-1630)

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Targeted gene Reference

60 16S rRNA55 550 16S rRNA64 162 CRISPR This study60 507 CRISPR This study

64 198 CRISPR This study

Targeted gene Reference

60 16S rRNA

55 550 16S rRNA60 121 16S rRNA

60 146 16S rRNA60 281 16S rRNA

qPCR Tm (OC)

Amplicon size (bp)

145 (in E. coli) Sokol, et al. (2008)Matsuki, et al. (2004)

qPCR Tm (OC)

Amplicon size (bp)

467 (in E. coli) Nadkarni, et al. (2002)

Matsuki, et al. (2004)Furet, et al. (2004)

Firmesse, et al. (2007)Firmesse, et al. (2007)

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Table S15. List of 136 microbial genomes used to analyze human fecal RNA-Seq data.

Microbial strain name Accession numberActinomyces odontolyticus ATCC 17982 NZ_AAYI00000000Akkermansia muciniphila ATCC BAA-835 NC_010655Alistipes putredinis DSM 17216 NZ_ABFK00000000Anaerococcus hydrogenalis DSM 7454 NZ_ABXA00000000Anaerofustis stercorihominis DSM 17244 NZ_ABIL00000000Anaerostipes caccae DSM 14662 NZ_ABAX00000000Anaerotruncus colihominis DSM 17241 NZ_ABGD00000000Bacteroides caccae ATCC 43185 NZ_AAVM00000000Bacteroides capillosus ATCC 29799 NZ_AAXG00000000Bacteroides cellulosilyticus DSM 14838 NZ_ACCH00000000Bacteroides coprocola DSM 17136 NZ_ABIY00000000Bacteroides coprophilus DSM 18228 NZ_ACBW00000000Bacteroides dorei DSM 17855 NZ_ABWZ00000000Bacteroides eggerthii DSM 20697 NZ_ABVO00000000Bacteroides finegoldii DSM 17565 NZ_ABXI00000000Bacteroides fragilis 3_1_12 NZ_ABZX00000000Bacteroides fragilis NCTC 9343 NC_003228Bacteroides fragilis YCH46 NC_006347Bacteroides intestinalis DSM 17393 NZ_ABJL00000000Bacteroides ovatus ATCC 8483 NZ_AAXF00000000Bacteroides plebeius DSM 17135 NZ_ABQC00000000Bacteroides sp. 1_1_6 NZ_ACIC00000000Bacteroides sp. D1 NZ_ACAB00000000Bacteroides sp. D2 NZ_ACGA00000000Bacteroides stercoris ATCC 43183 NZ_ABFZ00000000Bacteroides thetaiotaomicron 3731 NC_Bthetaiotaomicron3731Bacteroides thetaiotaomicron 7330 NC_Bthetaiotaomicron7330Bacteroides thetaiotaomicron VPI-5482 NC_004663Bacteroides uniformis ATCC 8492 NZ_AAYH00000000Bacteroides vulgatus ATCC 8482 NC_009614Bacteroides WH2 NC_BWH2Bacteroides xylanisolvens XB1A NC_BxylanisolvensXB1ABifidobacterium adolescentis ATCC 15703 NC_008618Bifidobacterium adolescentis L2-32 NZ_AAXD00000000Bifidobacterium angulatum DSM 20098 NZ_ABYS00000000Bifidobacterium animalis subsp. lactis AD011 NC_011835Bifidobacterium animalis subsp. lactis CNCM I-2494 CP002915Bifidobacterium animalis subsp. lactis HN019 NZ_ABOT00000000

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Bifidobacterium breve DSM 20213 NZ_ACCG00000000Bifidobacterium catenulatum DSM 16992 NZ_ABXY00000000Bifidobacterium dentium NC_BdentiumBifidobacterium gallicum DSM 20093 NZ_ABXB00000000Bifidobacterium longum DJO10A NC_010816Bifidobacterium longum NCC2705 NC_004307Bifidobacterium pseudocatenulatum DSM 20438 NZ_ABXX00000000Blautia hansenii DSM 20583 NZ_ABYU00000000Blautia hydrogenotrophica DSM 10507 NZ_ACBZ00000000Bryantella formatexigens DSM 14469 NZ_ACCL00000000Butyrivibrio crossotus DSM 2876 NZ_ABWN00000000Catenibacterium mitsuokai DSM 15897 NZ_ACCK00000000Citrobacter youngae ATCC 29220 NZ_ABWL00000000Clostridium asparagiforme DSM 15981 NZ_ACCJ00000000Clostridium bartlettii DSM 16795 NZ_ABEZ00000000Clostridium bolteae ATCC BAA-613 NZ_ABCC00000000Clostridium hiranonis DSM 13275 NZ_ABWP00000000Clostridium hylemonae DSM 15053 NZ_ABYI00000000Clostridium leptum DSM 753 NZ_ABCB00000000Clostridium methylpentosum DSM 5476 NZ_ACEC00000000Clostridium nexile DSM 1787 NZ_ABWO00000000Clostridium ramosum DSM 1402 NZ_ABFX00000000Clostridium scindens ATCC 35704 NZ_ABFY00000000Clostridium sp. L2-50 NZ_AAYW00000000Clostridium sp. M62/1 NZ_ACFX00000000Clostridium sp. SS2/1 NZ_ABGC00000000Clostridium spiroforme DSM 1552 NZ_ABIK00000000Clostridium sporogenes ATCC 15579 NZ_ABKW00000000Clostridium symbiosum NC_CsymbiosumCollinsella aerofaciens ATCC 25986 NZ_AAVN00000000Collinsella intestinalis DSM 13280 NZ_ABXH00000000Collinsella stercoris DSM 13279 NZ_ABXJ00000000Coprococcus comes ATCC 27758 NZ_ABVR00000000Coprococcus eutactus ATCC 27759 NZ_ABEY00000000Desulfovibrio piger ATCC 29098 NZ_ABXU00000000Desulfovibrio piger GOR1 NC_DpigerGOR1Dorea formicigenerans ATCC 27755 NZ_AAXA00000000Dorea longicatena DSM 13814 NZ_AAXB00000000Enterobacter cancerogenus NC_EcancerogenusEscherichia coli str. K-12 substr. MG1655 NC_000913Escherichia fergusonii ATCC 35469 NC_011740

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Eubacterium biforme DSM 3989 NZ_ABYT00000000Eubacterium dolichum DSM 3991 NZ_ABAW00000000Eubacterium eligens ATCC 27750 NC_012778Eubacterium hallii DSM 3353 NZ_ACEP00000000Eubacterium rectale ATCC 33656 NC_012781Eubacterium rectale DSM17629 NC_Erectale_DSM17629Eubacterium ventriosum ATCC 27560 NZ_AAVL00000000Faecalibacterium prausnitzii A2-165 NZ_ACOP00000000Faecalibacterium prausnitzii M21/2 NZ_ABED00000000Fusobacterium sp. 4_1_13 NZ_ACDE00000000Fusobacterium varium ATCC 27725 NZ_ACIE00000000Helicobacter pylori HPAG1 NC_008086Holdemania filiformis DSM 12042 NZ_ACCF00000000Lactobacillus casei ATCC 334 NC_008526Lactobacillus casei DN114001* NC_LcaseiDN114001Lactobacillus delbrueckii DN100107* NC_LdelbrueckiiDN100107Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 NC_008054Lactobacillus delbrueckii subsp. bulgaricus CNCM I-1519* AGHW00000000Lactobacillus delbrueckii subsp. bulgaricus CNCM I-1632* AGFO00000000Lactobacillus reuteri DSM 20016 NC_009513Lactococcus lactis subsp. cremoris CNCM I-1631* AGHX00000000Lactococcus lactis subsp. cremoris MG1363 NC_009004Lactococcus lactis subsp. cremoris SK11 NC_008527Lactococcus lactis subsp. lactis Il1403 NC_002662M23A NC_M23AMethanobrevibacter smithii ATCC 35061 NC_009515Methanobrevibacter smithii DSM 2374 NZ_ABYV00000000Methanobrevibacter smithii DSM 2375 NZ_ABYW00000000Methanosphaera stadtmanae DSM 3091 NC_007681Mitsuokella multacida DSM 20544 NZ_ABWK00000000Parabacteroides distasonis ATCC 8503 NC_009615Parabacteroides johnsonii DSM 18315 NZ_ABYH00000000Parabacteroides merdae ATCC 43184 NZ_AAXE00000000Parvimonas micra ATCC 33270 NZ_ABEE00000000Prevotella copri DSM 18205 NZ_ACBX00000000Proteus penneri ATCC 35198 NZ_ABVP00000000Providencia alcalifaciens DSM 30120 NZ_ABXW00000000Providencia rettgeri DSM 1131 NZ_ACCI00000000Providencia rustigianii DSM 4541 NZ_ABXV00000000Providencia stuartii ATCC 25827 NZ_ABJD00000000Roseburia intestinalis L1-82 NZ_ABYJ00000000

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Ruminococcus bromii L263 NC_RbromiiL263Ruminococcus gnavus ATCC 29149 NZ_AAYG00000000Ruminococcus lactaris ATCC 29176 NZ_ABOU00000000Ruminococcus obeum ATCC 29174 NZ_AAVO00000000Ruminococcus torques ATCC 27756 NZ_AAVP00000000Shigella sp. D9 NZ_ACDL00000000Streptococcus infantarius subsp. infantarius ATCC BAA-102 NZ_ABJK00000000Streptococcus thermophilus CNCM I-1630* AGFN00000000Streptococcus thermophilus CNRZ1066 NC_006449Streptococcus thermophilus DN001147* NC_SthermophilusDN001147Streptococcus thermophilus LMD-9 NC_008532Streptococcus thermophilus LMG 18311 NC_006448Subdoligranulum variabile DSM 15176 NZ_ACBY00000000Vibrio cholerae O1 biovar eltor str. N16961 chromosome I* NC_002505Vibrio cholerae O1 biovar eltor str. N16961 chromosome II* NC_002506Victivallis vadensis ATCC BAA-548 NZ_ABDE00000000

* : reference genome not included in KEGG pathway coverage ratio calculations (Fig. S2)

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NC_Bthetaiotaomicron3731NC_Bthetaiotaomicron7330

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NC_Erectale_DSM17629

NC_LdelbrueckiiDN100107

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NC_SthermophilusDN001147