StartUp Health Insights 2016 Midyear Report

26
© 2016 StartUp Health, LLC A StartUp Health Insights TM Report Published July 6, 2016 | Report data through June 30, 2016 Report is inclusive of seed, venture, corporate venture and private equity funding Published: April 1, 2015 50+ MARKET FUNDING SPONSORED BY StartUp Health Insights Digital Health Funding Rankings 2016 Midyear Report TM TOP VENTURE FUNDING AND TOP MARKETS SPONSORED BY

Transcript of StartUp Health Insights 2016 Midyear Report

Page 1: StartUp Health Insights 2016 Midyear Report

© 2016 StartUp Health, LLC

A StartUp Health InsightsTM Report Published July 6, 2016 | Report data through June 30, 2016 Report is inclusive of seed, venture, corporate venture and private equity funding

Published: April 1, 2015

50+ MARKET FUNDING SPONSORED BY

StartUp Health Insights Digital Health Funding Rankings

2016 Midyear Report

TM

TOP VENTURE FUNDING AND TOP MARKETS SPONSORED BY

Page 2: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

The digital health market broke historic records for midyear funding as investment reached $3.9B. Seed and Series A financing rounds are substantially equal in number, demonstrating a still thriving early-stage innovation landscape. Most funding dollars are being funneled to Series A rounds, creating opportunities for companies with validated solutions.

2

2016 Midyear and Q2 Summary

1Rethinking Insurance: Oscar has continued to blaze an innovative trail through traditional health insurance as a new generation of mobile-literate, “young invincibles” look for affordable, engaging and simple solutions for their insurance. Similar models, successful in their own ways, have followed suit as three of the top 10 deals year to date focused on tech-centered insurance.

2Asia & the Middle East Make Their Mark: China, India and Israel have been adopting digital health solutions in significant ways over the last several years, rolling out massive technologies for populations facing nuanced, yet substantially similar, health challenges around the world.

3Early-Stage Ecosystem: There was an almost even amount of Seed and Series A deals in the first half of 2016, making up almost 65 percent of all funding rounds, though Series A deals garnered more capital. Companies receiving Seed financing are burdened with proving their model works on little capital, while opportunities for Series A financing remain abundant.

4Publicly Traded Pioneers: As Evolent Health climbs back to its original IPO price, shareholders wonder what this means for other publicly traded digital health companies and those considering public exits. While the real value of what these companies do may still be left for most to realize, the perceived value still remains lower than anticipated for many of these early innovators.

5Global Innovation: More than 7,600 startups around the world are developing solutions in digital health, based on StartUp Health Insights data. Innovation continues to thrive as borders between technologies, talent and nations disappear to spur real change in medical systems at home and abroad.

DEALS & FUNDING INVESTORS 50+ MARKET

Page 3: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

149

282

464

624566

498

234

3

Digital Health Funding Snapshot Year Over Year (2016 YTD)

$2B

$4B

$6B

$8B

2010 2011 2012 2013 2014 2015 2016 YTD

Q1 Q2 Q3 Q4 $1.7B

2016 demonstrated the strongest first half of a year, to date, with $3.9B total invested compared to the previous record of $3.5B in the first half of 2014. In alignment with past trends, funding continues to increase as deal count decreases.

Deal Count

$575M $755M $1.1B $1.5B

$3.5B $2.9B $3.9B

DEALS & FUNDING INVESTORS 50+ MARKET

Q1+Q2

$1.1B$2B

$2.4B$3B

$7B

$6B

$3.9B

Page 4: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

Digital Health Funding Snapshot Month Over Month

4

$0

$250,000,000

$500,000,000

$750,000,000

$1,000,000,000

$1,250,000,000

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

2013 2014 2015 2016 YTD

$1.25B

$1.00B

$0.75B

$0.50B

$0.25B

Comparing funding year over year, a clear pattern is evident in the deployment of capital forming with slower periods at the beginning of the year and during the summer, with May and September as major months for funding.

DEALS & FUNDING INVESTORS 50+ MARKET

Page 5: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

$0

$250,000,000

$500,000,000

$750,000,000

$1,000,000,000

$1,250,000,000

2010 2011 2012 2013 2014 2015 2016 YTD

R² = 0.6016

$320M Series B

Digital Health Funding Snapshot Month Over MonthThough funding looks like it took a significant dip in June of this year, this was largely due to the $500M Series A investment in Ping An Good Doctor in May.

$150M Series C

$37.5M Venture

$37.9M Venture

$101M Series B

$394M Venture

$33M Series B

$31M Series A

$400M Series C

$230M Series B

$500M Series C

R2 = 0.5564

$1.25B

$1.00B

$0.75B

$0.50B

$0.25B

$400M Venture

$500M Series A

DEALS & FUNDING INVESTORS 50+ MARKET

5

Page 6: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

Company $ Invested Market / Subsector Notable Investor

1 $500M Patient Experience / Navigation Undisclosed

2 $400M Wellness / Insurance Khosla Ventures

3 $220M Big Data / Diagnostics GE Ventures

4 $175M Big Data / Personalized Health Roche

5 $160M Wellness / Insurance Spark Capital

6 $100M Personalized Health / Genomics Lightspeed Ventures

6 $100M Wellness / Behavioral Health Hinduja Group

8 $95M Wellness / Physical Fitness Summit Partners

9 $80M Wellness / Insurance Bessemer Venture Partners

10 $75M Medical Device / Diagnostics Orbimed

Chinese patient scheduling app, Ping An Good Doctor, leads 2016 with a half billion dollar deal. Companies rethinking the way we experience insurance are high in funding as Oscar, Clover and Bright Health scale their solutions.

The Top 10 Largest Deals of 2016 YTD

DEALS & FUNDING INVESTORS 50+ MARKET

6

Page 7: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

Company $ Invested Market / Subsector Notable Investor

1 $9.3M Personalized Health / Genomics Health Catalyst Capital Management

2 $9.2M Medical Device / Nutrition Foundry Group

3 $9.1M Medical Device / Mobile App Empire Capital Partner

4 $9.0M Medical Device / Wellness Andreessen Horowitz

4 $9.0M Wellness / Big Data TransLink Capital

6 $8.7M Personalized Health / Genomics Pilot Growth Equity

7 $8.5M Wellness / Nutrition Undisclosed

8 $8.2M Research / Patient Engagement Undisclosed

8 $8.2M Patient Experience / Telemedicine Partech Ventures

10 $8.0M Wellness / Nutrition SevenVentures Austria

The top deals under $10M show a diverse cross section of digital health innovation. While the most active markets are evenly represented, there is an increase in genome-sequencing companies and medical device companies on this list.

The Top 10 Deals Under $10M of 2016 YTD

DEALS & FUNDING INVESTORS 50+ MARKET

7

Page 8: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

Market $ Invested # of Deals Notable Deals

1 Patient / Consumer Experience $958M 51 • Livongo • DocPlanner

2 Wellness $854M 25 • Bloodbuy • Healthline

3 Personalized Health / Quantified-Self $524M 19 • Guardant Health • Prenetics

4 Big Data / Analytics $406M 19 • Lumiata • Apixio

5 Workflow $328M 43 • Maxwell Health • Captricity

6 Clinical Decision Support $234M 13 • ePatientFinder • RubiconMD

7 Medical Device $227M 25 • MindMaze • Halo Neuroscience

8 E-Commerce $172M 19 • Healthline • Bloodbuy

9 Research $65M 17 • Elemental Machines • Strata Oncology

10 Population Health $55M 18 • Virtual Health • Lightbeam Health Solutions

The Top 10 Most Active Markets of 2016 YTD

DEALS & FUNDING INVESTORS 50+ MARKET

8

Patient / consumer experience remains a dominant market in the first half of the year, leading significantly in both funding amount and deal count.

Page 9: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

The Top 10 Most Active US Metro Areas of 2016 YTD

DEALS & FUNDING INVESTORS 50+ MARKET

Metro Area

1 SF Bay Area

2 New York City

3 San Diego

4 Boston

5 Chicago

6 Minneapolis

7 Los Angeles

8 Salt Lake City

9 Philadelphia

10 Phoenix$286M

$753M

$131M

$70M$967M

Boston

$122M Chicago

$54M

$67M

Phoenix(3 Deals)

San Diego(6 Deals)

SF Bay Area(50 Deals)

Salt Lake City(1 Deal)

Philadelphia(6 Deals)

(8 Deals)

New York City(26 Deals)

(10 Deals)$107M

Minneapolis(6 Deals)

$76M

Los Angeles(6 Deals)

The San Francisco Bay Area and NYC Metro Area continue their dominance as hotbeds for digital health funding. New hubs continue to emerge and remain in the top 10 including Los Angeles, San Diego, Chicago and Minneapolis.

9

Page 10: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

Notable International Deals of 2016 YTD

China

Innovations continue to explode abroad as India pushes through its giant consumer-centric healthcare system, China begins connecting millions of patients to doctors and Israel pushes groundbreaking software solutions.

Chengdu, China $50M Series C

May 2016

Shanghai ,China $500M Series A

May 2016

Beijing, China $15M Series B

March 2016

Gurgaon, India $16M Series B

April 2016

Netherlands $11M Series A

March 2016

Toronto, Canada $25M Series A

June 2016

London, UK $25M Series A

June 2016

Tel Aviv, Israel $25M Series G

June 2016

Munich, Germany $45M Series C

March 2016

DEALS & FUNDING INVESTORS 50+ MARKET

10

Page 11: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

2010

2011

2012

2013

2014

2015

2016

0% 25% 50% 75% 100%

Seed Series A Series B Series C Series D Series E Series F+

Through the first half of the year we have seen an equal amount of Seed and Series A deals. These early-stage deals account for more than 65 percent of deal volume, speaking to investors’ continued interest in new innovations and business models.

Deal Activity by Stage 2016 YTD

32% 33% 10%18% 4%

Deal Count

121

233

305

446

382

285

155 (YTD)

DEALS & FUNDING INVESTORS 50+ MARKET

11

Page 12: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

Despite a 1:1 distribution in the number of Seed and Series A rounds, actual funding is disproportionate, with a 1:5 ratio, respectively. Series A financing totals $400M in the first half of the year, excluding Ping An Good Doctor, while Seed financing is under $100M. Series B climbs to $600M, while the later rounds drop off in amount.

Funding Activity by Stage in 2016 YTD

34% 34% 9%17% 4%

$0M

$175M

$350M

$525M

$700M

Seed Series A* Series B Series C Series D Series E

Series A

DEALS & FUNDING INVESTORS 50+ MARKET

12

*Ping An Good Doctor’s $500M Series A round not included in calculations

Page 13: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

13

Deal Size Ranges & Medians by Stage for 2016 YTD

$0 $300M

While mid-stage deals displayed the greatest range of deal size at more than $200M, mid-stage and late-stage median amounts were very close, with early-stage deal size median considerably lower.

$7.3M $15.0M $41.7M

$11M $100M

$2.5M $220M

$52K $25M

$14M

$3.9M

$15.5M

Late-stage (Series D+)Mid-stage (Series B + Series C)Early-stage (Seed + Series A*)

$3.9M

$17M

$21M

DEALS & FUNDING INVESTORS 50+ MARKET

*Ping An Good Doctor’s $500M Series A round not included in calculations

Page 14: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

Most Active Venture Investors of 2016 YTD

DEALS & FUNDING INVESTORS 50+ MARKET

Firm 2016 YTD Deals 2015 Deals Stage

Early Mid Late

1 8 9

1 8 10

3 7 2

4 5 5

4 5 1

4 5 6

7 4 1

7 4 6

7 4 1

7 4 5

The first six months of the year have been an active period for the 10 most active investors as all are on pace to surpass their 2015 deal count, with half of the firms already meeting or exceeding the number.

14

Page 15: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

Investor Volume of 2016 YTD

15

0

100

200

300

400

2016 YTD

2157

368

1 Deal 2 Deals 3+ Deals

Inve

stor

Cou

nt

# of Deals by Investor

2016 continues to demonstrate that the appetite for investment in the digital health sector is not waning. So far this year, close to 450 investors have deployed capital in the sector, with 21 organizations investing in more than three deals.

DEALS & FUNDING 50+ MARKETINVESTORS

21

Page 16: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

209

315 339

506

602 611

446

Number of Investors Year Over YearInvestors have been converging on the digital health industry, more than doubling the unique investor count since 2010. 2016 shows no sign of slowing down as the mid-year point tracked close to 450 discrete active investors in the space.

# of Unique Investors

$1.6B

$1.1B

0

100

200

300

400

500

2010 2011 2012 2013 2014 2015 2016 YTD

1 2 3 4 5 6+

Inve

stor

Cou

nt

# of Deals by Investor

DEALS & FUNDING 50+ MARKETINVESTORS

16

Page 17: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

Looking Back on Digital Health IPOs of 2015

Pop. Health

$101.3M Pre-IPO VC Funding

$1,120M(Market Cap

6/29/16)

$195M on opening (6/8/15)

1.06%

Wearables

$66M Pre-IPO VC Funding

$2,660M (Market Cap

6/29/16)

$732M on opening (6/19/15)

(60.53%)

$108.9M Pre-IPO VC Funding

Wellness

$661.4M(Market Cap

6/29/16)

$101M on opening (6/22/15)

(4.87%)

$0

$15

$30

$45

$60 52-Week High & Low Share Price

Genomics

$154.1M Pre-IPO VC Funding

$584.1M (Market Cap

6/29/16)

$180M on opening (7/7/15)

(46.36%) (51.24%)

Telemedicine

$157M on opening (7/1/15)

$93M Pre-IPO VC Funding

$680.8M (Market Cap

6/29/16)

$102M on opening (2/13/15)

$195.5M Pre-IPO VC Funding

Genomics

(56.23%)

$232.7M (Market Cap

6/29/16)

Shar

e Pr

ice

($)

As digital health companies find their identities in the public market, Evolent Health has risen to their initial offering price. Other public companies still fluctuate as the the market attempts to put a value on these new technologies.

DEALS & FUNDING 50+ MARKETINVESTORS

17

Page 18: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

As the overall digital health industry continues to expand, startups serving 50+ consumers - either directly or through providers, payors and other healthcare stakeholders - are increasingly attracting investment.

Defining the 50+ Market in Digital Health

The 50+ relevant category includes companies, both B2C and B2B2C, with products or services that also serve 50+ consumers. This excludes practice management solutions, compliance software, lab support tools and other enterprise systems that do not have a consumer touchpoint, as well as companies specifically targeting other demographics like children and young families.

The 50+ focused category includes B2C companies that specifically target 50+ consumers and B2B2C companies that provide products and services to payors, providers and others that serve 50+ consumers.

Emergency Detection and Response

Physical Fitness

Diet and Nutrition

Behavioral and Emotional Health

Medical Management

Aging With Vitality

Social Engagement

Vital Signs Monitoring

Care Navigation

18

DEALS & FUNDING INVESTORS 50+ MARKET

This report spotlights two categories of startups: 50+ relevant and 50+ focused companies. Companies in both categories align with at least one of AARP’s nine areas of opportunity featured in the graphic.

Page 19: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

20%

40%

60%

80%

100%

53%

61%57%

52% 51%48%

62%

47%50%

47% 45%49%

45%51%

Deals Funding

50+ Market Investments as % of Total Investments 2016 YTD

47%

45%

2010 2012 2013 20142011 2015

26%

2016 YTD

Investors in 2016 continue to focus approximately half of their funds and half of their deals on 50+ relevant companies. The opportunity to continue to support these types of solutions remains strong in the second half of the year.

DEALS & FUNDING INVESTORS 50+ MARKET

19

Page 20: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

Subsectors of Growth in the 50+ Sector

47%

45%

26%

Though the entire 50+ market continues to grow, the most active subsectors vary in terms of funding since 2010. Personalized health has become an explosive winner while patient/ consumer experience maintains strong and steady growth.

20

$0M

$100M

$200M

$300M

$400M

2010 2011 2012 2013 2014 2015 2016 YTD

Medical Device Patient/ Consumer Experience Personalized Health Wellness

DEALS & FUNDING INVESTORS 50+ MARKET

Page 21: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

1% 21% 41% 60% 80% 100%

Seed Series A Series B Series C Series D Series E+

50+ Market Investments by Round vs. Total Landscape

DEALS & FUNDING INVESTORS 50+ MARKET

Industry

Investors relevant to the 50+ market are significantly farther along in round type with less than 20 percent of deals being early-stage (Seed or Series A). Series B deals make up the majority, at almost half of all funding in the 50+ market.

21

50+ Market

40%20%0%

13%

51%4%

4%

20% 14%

41% 18% 20% 4%

3% 8%

Page 22: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

Investors around the globe are funding companies that address the needs of 50+ consumers at all stages, with notable involvement from corporate and strategic investors.

The Top 50+ Market Venture Investors of 2016 YTD

DEALS & FUNDING INVESTORS 50+ MARKET3+

Dea

ls2

Dea

ls

22

Page 23: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

Sectors: • We have a broad view of digital health and believe that the current trend is a cross-pollination of technology and data with all aspects of health and

healthcare. StartUp Health InsightsTM tracks companies that enable health, wellness and the delivery of care through data / analytics, sensors, mobile, internet-of-things, 3D printing and genomics and personalized medicine.

• Investments in subsectors are not mutually exclusive as deals are tagged with multiple subsectors. • An extensive database quality assessment was conducted in 2015. A new system was implemented allowing StartUp Health to track innovation with

enhanced granularity. Additionally, gaps in funding data were researched and added into our database enabling us to identify fundings previously unaccounted for in past reports.

Stage of funding: • StartUp Health InsightsTM records only publicly available data on cash for equity investments as the cash is actually received by the company. StartUp

Health InsightsTM is inclusive of all accelerator, seed, venture, corporate venture and private equity funding. • Early stage: The company has raised a Seed or Series A round • Mid stage: The company has raised a Series B or Series C round • Late stage: The company has raised a Series D or other growth equity round • StartUp Health also tracks incubator rounds and other financings into privately-held entities (e.g. “unnamed” venture rounds, strategic investments, growth

equity and private equity). • In tabulating deal activity by stage we exclude rounds not clearly associated with a specific stage.

Sources: • Funding data is from StartUp Health InsightsTM, the most comprehensive funding database for digital health, and managed by the StartUp Health team.

Information, data and figures represent only publicly available data, unless otherwise confirmed by the company receiving capital or a participating investor. • Data for acquisitions slide is provided by a range of sources including StartUp Health InsightsTM, CrunchBase, AngelList and news reports. • StartUp Health works to ensure that the information contained in the StartUp Health InsightsTM Report has been obtained from reliable sources. However,

StartUp Health cannot warrant the ultimate validity of the data obtained in this manner. All data is subject to verification with the venture capital firms and/or the investee companies. Results are updated periodically. Therefore, all data is subject to change at any time. If you find an error please let us know so we can correct it.

This report is provided for informational purposes and was prepared in good faith on the basis of public information available at the time of publication without independent verification. StartUp Health does not guarantee or warrant the reliability or completeness of the data nor its usefulness in achieving any particular purposes. StartUp Health shall not be liable for any loss, damage, cost or expense incurred by reason of any persons use or reliance on this report. This report is a proprietary aggregation of publicly available data and shall not be forwarded or reproduced without the written consent of StartUp Health.

23

Our Methodologies

Page 24: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

StartUp Health is a global health innovation community leading the movement to transform health by organizing and investing in Healthcare Transformers. With a family of more than 300 Healthcare Transformers and 150 companies, StartUp Health spans more than a dozen countries and 60 cities. StartUp Health’s lifetime platform for entrepreneurs includes the StartUp Health Academy, StartUp Health Network, StartUp Health Studio and StartUp Health Ventures. StartUp Health was founded in 2011 by Steven Krein and Unity Stoakes and is chaired by former Time Warner CEO, Jerry Levin.

StartUp Health’s notable strategic partners and investors include AARP, AON, Aurora Health Care, California Health Care Foundation, Steve Case, Cleveland Clinic, Conifer Health Solutions, Mark Cuban, Esther Dyson, Brad Feld, Genentech, GE Ventures, Kaiser Permanente Ventures, Robert Wood Johnson Foundation and SeventySix Capital. Learn more at startuphealth.com and follow @startuphealth.

24

About StartUp Health

StartUp Health InsightsTM Report Contributors: Troy Bannister, Polina Hanin, Jennifer Hankin, Nicole Kinsey, Tara Salamone

Page 25: StartUp Health Insights 2016 Midyear Report

Disclosure: Information, data and figures represent publicly available data through 6/30/16. © 2016 StartUp Health, LLCNote: StartUp Health InsightsTM is inclusive of all seed, venture, corporate venture and private equity funding. • Source: StartUp Health Insights | www.startuphealth.com/insights

StartUp Health Companies

Page 26: StartUp Health Insights 2016 Midyear Report

© 2016 StartUp Health, LLC

A StartUp Health InsightsTM Report Published July 6, 2016 | Report data through June 30, 2016 Report is inclusive of seed, venture, corporate venture and private equity funding

Published: April 1, 2015

50+ MARKET FUNDING SPONSORED BY

StartUp Health Insights Digital Health Funding Rankings

2016 Midyear Report

TM

TOP VENTURE FUNDING AND TOP MARKETS SPONSORED BY