apoplex medical technologies GmbHDelaware Avenue 1-3 • 66953 Pirmasens • Germany

Phone: +49(0) 6331 698 998-0 • Fax: +49(0) 6331 698 998-19Email: info@apoplexmedical.com • Web: www.apoplexmedical.com

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SRA®clinic: Only 4 simple steps to get a result:

Automatic ECG derivation directly from the patient monitor

or:

traditional ECG derivation via long-term ECG recorder (incl. in our service)

1

The data are sent via an encrypted and secured connection to our analysis server and examined

2

Prompt transmission of the analysis report as PDF file

Independent diagnosis by verification of the supplied ECG-section in the analysis report

or:

through the cardiologist network of apoplex medical technologies

4

1 Gomis M, Dávalos A, et al. (2020), Stroke Risk Analysis, a System With a High Detection Rate of Atrial Fibrillation in Stroke and Transient

Ischemic Attack, Stroke 51

2 Rizos T, Guntner J, et al. (2012) Continuous stroke unit electrocardiographic monitoring versus 24-hour Holter electrocardiography for detection

of paroxysmal atrial fi brillation after stroke; Stroke 43 (10)

3 Uphaus T, Lange B, et al. (2019), Automatic Analysis of prolonged Holter-ECG Data to identify paroxysmal Atrial Fibrillation in acute ischemic

stroke patients: Ready to displace physicians, wissenschaftliche Session auf der European Stroke Organisation Conference 2019

4 Reinke F, Bettin M, et al. (2018), Refinement of detecting atrial fibrillation in stroke patients: results from the TRACK-AF Study, Eur J Neurol. 25

Our experienced me

dical product consu

ltants

will be happy to advi

se you:

info@apoplexmedi

cal.de

“The results are available very quickly and the detection rate of pAF has distinctly increased. In other words: It couldn`t be more efficient.” Dr Kathrin Lesser, Waldklinikum Gera

3

SRA®clinic Your competent partner in

stroke prevention

Efficiency has been

proven several time

s in

clinical studies

Risk factor Atrial Fibrillation

SRA®clinic

“With SRA®clinic we have now an intel-ligent telemedical ECG analysis method on hand [...].”

Prof Dr Thomas Duning, University Hospital

Münster, Clinic for Neurology

“The use of SRA®clinic relieves the staff considerably and we can find out very quickly whether the patient suffers from paroxysmal atrial fibrillation.”

Prof Dr Günter Seidel, Asklepios-

Klinik Nord - Heidberg, Hamburg

“Without any recognisable reference to patients, the monitoring data is sent to the external analysis server via a secure VPN connection. There they are combined to form a 24-hour ECG and tested for AF via algorithmic processes.”

Information Technology Division of the Universi-

ty Hospital Hamburg-Eppendorf (UKE)

Safe detection of atrial fibrillation

NEW

apoplex medical technologies is specialized in the development of applications to support the detection of atrial

fibrillation (AF). The core element of our stroke risk analysis for clinical use (SRA®clinic) is, in addition to the fully

automated detection of indications of atrial fibrillation, the identification of patients with an increased risk of paro-

xysmal AF (pAF) in flicker-free episodes. The resulting selection of patients makes it possible to carry out any further

diagnosis in a targeted manner.

If required with cardiological diagnosis

Our network of cardiologists complements the SRA®clinic screening perfectly.

Our users receive the cardiological results promptly and unbureaucratically, so

that further decisions can be made quickly.

• Guaranteeing the security of sensitive patient data through

pseudonymization

• Environment of our servers is ISO 27001 certified

• Over 130 hospitals already trust us

Guaranteed data security

• Helps to reduce the average duration of stays

• Supports your digitization strategy

• Independent of the brand/type of your hardware

Efficient and cost-transparent

• Reliable results about 3 times faster1

• Doubling the detection rate of AF

• Screening as long as needed with no additional costs

• Patient selection through high negative predictive value4

• identifying a risk of pAF in flicker-free episodes4

• Longtime experience with AI technology

Innovation for the well-being of your patients

European Stroke Organisation Conference

In this multi-centre study the effectiveness of the detection of pAF

with SRA® in comparison to routinely personnel-assisted analysis

(SA) in a large patient cohort (N=1034) was examined. SRA® de-

tected pAF more numerous than personnel-assisted analysis (SA

59 vs. RA 45) with a significantly higher sensitivity.3

Stroke: A Journal of Cerebral Circulation

These excellent results were confirmed in a recent multi-centre

study. The use of a long-term ECG recorder in combination with

SRA® doubled the detection rate (9,7 % hSRA vs. 4,3 CEM) of pAF

in one-third of the time (23,9 h hSRA vs. 66,5 h CEM).1

European Journal of Neurology

This monocentric prospective study verified: SRA® is reliable in

the prediction of AF with a high negative predictive value (96%).

Thus, SRA® can serve as a cost-effective triage tool to identify

patients at risk for AF who may benefit from further longtime

ECG monitoring.4

Confidence

through excellent

clinical evidence

96 %Negative predictive value of atrial fibrillation

A comparative study at the Department of Neurology at Heidel-

berg University Hospital showed that SRA®clinic is significantly

superior to standard monitoring. The detection rate of pAF in-

creased by 40% compared to standard monitoring - and by as

much as 170% compared to the 24-hour Holter.2

Monitoring ECG

with SRA® (aCEM)

24-h-Holter

Recorder

+ 170%

Detection rate for AF

SRA®

96,7

%

Cardiologists

73,8

%+ 31%

Sensitivity of AF detection

2x higher detection of pAF faster detection of pAF3x

2

3

4