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![Page 1: Speech Impairment in Parkinson’s Disease is Improved by Transcranial Application of Electromagnetic Fields By: Reuven Sandyk.](https://reader036.fdocuments.net/reader036/viewer/2022082818/56649ead5503460f94bb3fec/html5/thumbnails/1.jpg)
Speech Impairment in Parkinson’s Disease is Improved
by Transcranial Application of Electromagnetic Fields
By: Reuven Sandyk
![Page 2: Speech Impairment in Parkinson’s Disease is Improved by Transcranial Application of Electromagnetic Fields By: Reuven Sandyk.](https://reader036.fdocuments.net/reader036/viewer/2022082818/56649ead5503460f94bb3fec/html5/thumbnails/2.jpg)
Parkinson’s Disease
• Frequently associated with speech disturbance
• Affects 50-70% of patients
• An even greater percentage in advanced stages of disease
![Page 3: Speech Impairment in Parkinson’s Disease is Improved by Transcranial Application of Electromagnetic Fields By: Reuven Sandyk.](https://reader036.fdocuments.net/reader036/viewer/2022082818/56649ead5503460f94bb3fec/html5/thumbnails/3.jpg)
Parkinsonian Speech Impairment
• Monotonous pitch
• Slow rate
• Decrease in volume (hypophonia)
• Symptoms generally worse when patient is tired or anxious
![Page 4: Speech Impairment in Parkinson’s Disease is Improved by Transcranial Application of Electromagnetic Fields By: Reuven Sandyk.](https://reader036.fdocuments.net/reader036/viewer/2022082818/56649ead5503460f94bb3fec/html5/thumbnails/4.jpg)
• In mid to advanced stages– Phonemes are less articulated
• Produces a hypokinetic dysarthria (stuttering)
– Festinating speech
• Dysfluency may become worse as disease progresses
![Page 5: Speech Impairment in Parkinson’s Disease is Improved by Transcranial Application of Electromagnetic Fields By: Reuven Sandyk.](https://reader036.fdocuments.net/reader036/viewer/2022082818/56649ead5503460f94bb3fec/html5/thumbnails/5.jpg)
Hypothesis
• Treatment with weak electromagnetic fields (EMFs) applied transcranially
![Page 6: Speech Impairment in Parkinson’s Disease is Improved by Transcranial Application of Electromagnetic Fields By: Reuven Sandyk.](https://reader036.fdocuments.net/reader036/viewer/2022082818/56649ead5503460f94bb3fec/html5/thumbnails/6.jpg)
Case Report
• 52 year old radiologist • Freezing of gate, increased difficulties with
hypophonia and with articulation• Mental depression, chronic insomnia• Anxiety and autonomic symptoms• Hyperkinetic dysarthria-particulaly severe
during periods of mental stress• Started on serotonergic medication one
month before treatment started
![Page 7: Speech Impairment in Parkinson’s Disease is Improved by Transcranial Application of Electromagnetic Fields By: Reuven Sandyk.](https://reader036.fdocuments.net/reader036/viewer/2022082818/56649ead5503460f94bb3fec/html5/thumbnails/7.jpg)
Treatment
• Four years, one treatment session each week
• Treatment session
• Patient continued to take serotonergic and antiParkinsonian medications
![Page 8: Speech Impairment in Parkinson’s Disease is Improved by Transcranial Application of Electromagnetic Fields By: Reuven Sandyk.](https://reader036.fdocuments.net/reader036/viewer/2022082818/56649ead5503460f94bb3fec/html5/thumbnails/8.jpg)
Results
• 80-90% improvement in speech • Impact of treatment is best the day after• Effect of treatment lasts 5-6 days• Continues to experience “on-off”
fluctuations• Dramatic improvement in cognitive
functions• Speech impairment was one of first
symptoms to reappear
![Page 9: Speech Impairment in Parkinson’s Disease is Improved by Transcranial Application of Electromagnetic Fields By: Reuven Sandyk.](https://reader036.fdocuments.net/reader036/viewer/2022082818/56649ead5503460f94bb3fec/html5/thumbnails/9.jpg)
Discussion
• Stuttering observed in young children• Acquired stuttering is rarely observed in
adults• Transient stuttering-left hemispheric
lesions• Acquired stuttering-bilateral cerebral
lesions • Prefrontal lobe, caudate-putamen, limbic
system
![Page 10: Speech Impairment in Parkinson’s Disease is Improved by Transcranial Application of Electromagnetic Fields By: Reuven Sandyk.](https://reader036.fdocuments.net/reader036/viewer/2022082818/56649ead5503460f94bb3fec/html5/thumbnails/10.jpg)
• Many symptoms associated with decreased levels of serotonin
• SSRIs may improve speech impairment
• Mechanisms by which EMFs improved speech impairment – Synaptic level– Synergistic interaction
![Page 11: Speech Impairment in Parkinson’s Disease is Improved by Transcranial Application of Electromagnetic Fields By: Reuven Sandyk.](https://reader036.fdocuments.net/reader036/viewer/2022082818/56649ead5503460f94bb3fec/html5/thumbnails/11.jpg)
Conclusion
Transcranial applications of EMFs may provide a novel, nonpharmacologic approach to the management of speech impairment associated with Parkinsonism