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    Faculty of Medicine

    Ain shams universi

    Department of toxi

    SNA

    y

    ology

    KE BIEdite

    Ahme

    SUPE

    DR.

    ESBY/Mohammed

    d Ghanem

    RVISOR /

    ARY

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    Snake bites by Mohamed A. Ghanem 2008

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    Aim of the search

    To spot light on snake bites types.

    To spot light on effects of snake bites.

    To spot light on first aid in case of bit.

    Treatment procedure of snake bite.

    To spot light on mechanism of snake venoum.

    Introduction

    Snakes often bite their prey when feeding, but occasionally they also bite humans.

    People can avoid and treat snakebites by knowing their etiology, along with prevention

    tips, and first-aid and hospital treatment.

    ENVENOMATION

    Most snakebites are caused by non-venomous snakes. Of the roughly 3,000 known

    species of snake found worldwide, only 15 percent are considered dangerous to

    humans.Snakes are found on every continent except Antarctica.

    Venomatous snakes : Poisonous snake bites include bites by any of the following:Cobra , Copperhead

    ,Coral snake ,Cottonmouth (water moccasin),Rattlesnake.

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    Snake bites

    Frequency and statistics :

    resulting in perhaps 125,00

    the summer season whentropical regions report mor

    and between 17 and 27 ye

    morbidity (fig.1).

    [Fig. 1]

    PREVENTI Avoid areas where s

    Even though most s

    any snake unless yo

    If you hike often, co

    stores). Do not use

    and suction bulbs.

    Don't provoke a sna

    Tap ahead of you wi

    see your feet. Snak When hiking in an a

    possible.

    SymptomsIn principle, snake venoms

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    some estimates put the number at 2.5 m

    0 deaths. Worldwide, snakebites occur

    nakes are active and humans are outdosnakebites than anywhere else. Victims

    rs of age. Map showing global distributi

    Nnakes may be hiding, such as under roc

    akes are not poisonous, avoid picking u

    u have been properly trained.

    sider buying a snake bite kit (available f

    lder snake bite kits, such as those cont

    ke. That is when many serious snake bit

    th a walking stick before entering an are

    s will try to avoid you if given enough wea known to have snakes, wear long pa

    act in three 'different' ways:

    2008

    illion bites per year,

    ost frequently in

    ors. Agricultural andare typically male

    on of snakebite

    s and logs.

    p or playing with

    om hiking supply

    ining razor blades

    s occur.

    where you can't

    rning.ts and boots if

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    Snake bites

    1. haemotoxins, ie veno

    ability of the blood to

    2. neurotoxins, ie venommuscles and in the w

    breathing.

    3. cardiotoxins, ie veno

    circulatory failure and

    But as a number of

    involved in poisonin

    there are often typic

    Symptoms depend on the t

    Bleeding from wound ,Blurr

    ,Dizziness ,Excessive swe

    thirst ,Loss of muscle coor

    ,pulse ,Tissue death, Seve

    WeaknessRattlesnake bite

    a.Neurotoxic venom (Nerv

    The casualty has sp

    drooling.

    Difficulty breathing.

    Respiratory arrest.

    Dizziness.

    Tunnel vision or blur

    Visible increase in s

    Convulsions.

    Unconsciousness.

    This venom attacks

    synaptic vesicles, rethe muscles.

    b. Haemotoxic venom (poi

    Often no pain or sy

    Casualty feels letha

    Nausea and vomitin

    Constant bleeding f

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    s that split (haemolyse) the red blood c

    lot (coagulate).

    s that in particular paralyse nerve transrst case paralyse the muscles involved i

    s that have a direct harmful action on th

    shock.

    ther factors, including possible allergic r

    , the situation is often far more complex

    lly 'mixed' reactions and symptoms.

    ype of snake, but may include:

    ed vision ,Burning of the skin ,Convulsio

    ting ,Fainting ,Fang marks in the skin ,F

    ination ,Nausea and vomiting ,Numbnes

    e pain, Skin discoloration, Swelling at th

    are painful when they occur.

    e destroying)

    eech and swallowing difficulties often ac

    red vision.

    eating.

    the central nervous system by causing a

    sulting in the blockage of nerve impulses

    soning of blood)

    ptoms occur for 1 -3 hours and as long

    rgic with headaches.

    g may occur.

    om the bite wound.

    2008

    lls, or affect the

    ission to theswallowing and

    heart and lead to

    eactions, are also

    and unclear, and

    ns ,Diarrhea

    ver ,Increased

    s and tingling ,Rapid

    site of the bite,

    ompanied by

    high loss of the

    from the brain too

    as 8 hours.

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    Snake bites

    Bruising as well as

    Blood oozing from o

    This venom affectsloss of blood throug

    the organs will occu

    TreatmentF i r s t a i d

    1. Keep the person cal

    emergency room. R

    level to reduce the fl

    2. If you have a pump

    manufacturer's direc

    3. Remove any rings

    Create a loose splin

    4. If the area of the bit

    poisonous.

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    lood spots may occur under the skin.

    ther bodily openings.

    the blood clotting mechanism, resulting ih the bodily openings and if left untreate

    r.

    a i d

    m, reassuring them that bites can be eff

    strict movement, and keep the affected

    ow of venom.

    uction device (such as that made by Sa

    tions.

    r constricting items because the affecte

    to help restrict movement of the area.

    begins to swell and change color, the s

    2008

    headaches, andinternal bleeding of

    ctively treated in an

    area below heart

    yer), follow the

    area may swell.

    ake was probably

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    5. Monitor the person's vital signs -- temperature, pulse, rate of breathing, and

    blood pressure -- if possible. If there are signs of shock (such as paleness), lay

    the person flat, raise the feet about a foot, and cover the person with a blanket.6. Get medical help right away.

    7. Bring in the dead snake only if this can be done safely. Do not waste time

    hunting for the snake, and do not risk another bite if it is not easy to kill the

    snake. Be careful of the head when transporting it -- a snake can actually bite for

    up to an hour after it's dead (from a reflex).

    8. DO NOT

    DO NOT allow the person to become over-exerted. If necessary, carry the

    person to safety.

    DO NOT apply a tourniquet.

    DO NOT apply cold compresses to a snake bite.

    DO NOT cut into a snake bite with a knife or razor.

    DO NOT try to suck out the venom by mouth.

    DO NOT give the person stimulants or pain medications unless a doctor tells you

    to do so.

    DO NOT give the person anything by mouth.

    DO NOT raise the site of the bite above the level of the person's heart.

    P R E S S U R E I M M O B I L I Z A T I O N :

    pressure immobilization is not appropriate for cytotoxic bites such as those of

    most vipers but is highly effective against neurotoxic venoms such as those of

    most elapids. the object of pressure immobilization is to contain venom within a

    bitten limb and prevent it from moving through the lymphatic system to the vital

    organs in the body core

    a.Neurotoxic venom

    Keep casualty calm and advise not to move. Either sitting or lying down.

    Cover the site of the bite with a clean dressing and apply a pressure bandage

    from the start of the limb then wrapping towards the bite area. Splint and elevate the limb if possible.

    If a suction syringe is available, then use on the site of the bite within three

    minutes, any time after that would be prove useless. Dont use your mouth to

    suck the venom out as you may have a cut or mouth ulcer where the venom can

    enter through.

    Dont cut the sight of the bite as this may lead to infection of the wound.

    Keep the airways open and monitor respiration and heart rate.

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    Mouth to mouth respiration may be required to keep the casualty alive.

    Try to identify the snake if possible but dont waste time doing this. Dont try

    catching the snake if it is still alive as this may result in another snake-bite. Transport casualty to hospital promptly.

    Neurotoxic venom is extremely powerful, so a tourniquet may be used if the

    casualty is far from any hospital. The tourniquet should be released and put back

    on every 10 15 minutes to allow for blood circulation.

    b.Haemotoxic venom

    Keep casualty calm and advise not to move. Either sitting or lying down.

    Cover the site of the bite with a clean dressing and apply a pressure bandage

    from the start of the limb, then wrapping towards the bite area.

    Splint and elevate the limb if possible.

    If a suction syringe is available, then use on the site of the bite within three

    minutes, any time after that would be prove useless. Dont use your mouth to

    suck the venom out as you may have a cut or mouth ulcer where the venom can

    enter through.

    Dont cut the sight of the bite as this may lead to infection of the wound.

    Keep the airways open and monitor respiration and heart rate.

    Try to identify the snake if possible but dont waste time doing this. Dont try

    catching the snake if it is still alive as this may result in another snake-bite.

    Transport casualty to hospital promptly.

    Anti-venom

    Anti-venom is made up of the antibodies from horses, sheep, goats, rabbits or

    dogs blood. Horses are more commonly used as more blood can be tapped.

    These animals are injected with small, non-lethal doses of venom over a period

    of time, with the dosage slowly increased. Their immune systems respond by

    creating antibodies to attack the venom. Once the animal is immune to the

    venom, the antibodies are then extracted to make anti-venom.

    Horse serum often causes serum sickness which is when the immune system

    reacts against the foreign proteins in the serum, the reaction can cause kidney

    failure and even death.

    Sheep serum is made by a purified fraction of the plasma, specifically refined

    antibody fragments and is a lot safer to use. Sheep serum is used for the

    treatment of the American rattlesnake bites.

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    A.Monovalent anti-venom this is made by injecting the venom of a specific

    species of snake into an animal to develop the anti-venom. This is effective

    against one specific snake species.

    B.Polyvalent anti-venom this is made by injecting the venom from a variety of

    different snake species into an animal to develop the anti-venom. This is effective

    against a broad range of snake species.

    References

    1. Wikipedia the free encyclopedia.

    http://en.wikipedia.org/wiki/Main_Page

    T I T L E S N A K E B I T

    2. Article base T I T L E S N A K E V E N O M S Y M P T O M S A N D

    T R E A T M E N T

    http://www.articlesbase.com/environment-articles/types-of-snake-venom-symptoms-and-treatment-543049.html