Mohammad Ghoreishi , MD Isfahan University of Medical sciences Isfahan, Irann
Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty,...
-
Upload
rodger-everett-horton -
Category
Documents
-
view
224 -
download
0
Transcript of Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty,...
![Page 1: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/1.jpg)
sjldllds
• ;l;sf’;’;s
بسم الله الرحمن الرحیم
1390 1Isfahan Medical Faculty, Biomedical Sciences Department
![Page 2: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/2.jpg)
Autonomic Nervous System
Autonomic Nervous System
Dr . Ebrahim Esfandiary
14/02/90
Dr . Ebrahim Esfandiary
14/02/90
1390 2Isfahan Medical Faculty, Biomedical Sciences Department
![Page 3: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/3.jpg)
1390 3Isfahan Medical Faculty, Biomedical Sciences Department
![Page 4: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/4.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
4
![Page 5: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/5.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
5Figure 12.2b
Autonomic System
Sympathetic divisionParasympathetic division
![Page 6: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/6.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
6
![Page 7: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/7.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
7
![Page 8: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/8.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
8
![Page 9: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/9.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
9
![Page 10: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/10.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
10
Sympathetic division
• Descending autonomic pathway
• Sympathetic center in spinal cord
• Sympathetic chain
• Sympathetic fibers
• Adrenal medulla
![Page 11: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/11.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
11
Parasympathetic division
• Descending autonomic pathway
• Dorsal nucleus of vagus
• Sacral parasympathetic center
• Vagus nerve
• Pelvic splanchnic fibers
![Page 12: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/12.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
12
پارا و سمپاتيك اعصاب زيع تومختلف ساختمانهاي در سمپاتيك
بدنپاراسمپاتيك و سمپاتيك بخش دو به خودكار عصبي سيستم
ميشود .تقسيم . در ميشود توزيع بدن تمام در سيستم اين سمپاتيكي بخش
مغزي حاليكه اعصاب طريق از پاراسمپاتيكي و 9، 7، 3بخشميشوند 10 توزيع لگني اسپالنكنيك اعصاب و .
دارند بدن در محدودتري توزيع پاراسمپاتيك اعصاب بنابراينندارند پاراسمپاتيك عصب سوماتيك بافتهاي ديگر عبارت به
عصب خودكار عصبي سيستم بخش هردو از احشاء بيشترمیکننددريافت
فقط بافتها براي بعضی مي كنند دريافت عصب بخش يك ازپاراسمپاتيكي مثال رشته فقط اشكي میکنددريافت غده
مي كنند دريافت سمپاتيكي رشته فقط جنسي و آدرنال غدد
![Page 13: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/13.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
13
Hitch hiking journey
• Autonomic system hitch hike through whole body along:
1- the somatic ( or visceral) nerves
2- Relevant arteries
![Page 14: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/14.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
14
Sympathetic Post ganglionic fibers distribute in one of the following 5 pathways:
![Page 15: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/15.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
Depart of A.S.B.S
![Page 16: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/16.jpg)
1390 16Isfahan Medical Faculty, Biomedical Sciences Department
![Page 17: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/17.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
17
![Page 18: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/18.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
18
![Page 19: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/19.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
19
![Page 20: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/20.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
20
Somatic Sympathetic ParasympatheticNerves Division Division
UMN
LMN
![Page 21: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/21.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
21
CNS P N S
![Page 22: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/22.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
22
PRE-GANGLIONICPRE-GANGLIONIC
![Page 23: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/23.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
23
GANGLIAGANGLIA
![Page 24: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/24.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
24
POST-GANGLIONICPOST-GANGLIONIC
![Page 25: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/25.jpg)
1390 25Isfahan Medical Faculty, Biomedical Sciences Department
![Page 26: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/26.jpg)
1390 26Isfahan Medical Faculty, Biomedical Sciences Department
![Page 27: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/27.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
27
![Page 28: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/28.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
28
![Page 29: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/29.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
![Page 30: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/30.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
Depart of A.S.B.S
![Page 31: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/31.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
31
![Page 32: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/32.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
32
Autonomic Efferent: Basic Principles• Somatic efferent path has just 1 neuron• Autonomic efferent path has 2 neurons:
– Preganglionic and postganglionic
• Sympathetic system is in the thoracolumbar region• Parasympathetic is cranio-sacral in location
![Page 33: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/33.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
33
Sympathetic System General Features:
• Long postganglionic fibers • Pre Gan N / Post Gan N = Very small ratio or high
divergence = 1/5
![Page 34: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/34.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department 34
Parasympathetic System: General Features
• Pre Gan N / Post Gan N = small ratio or low divergence += 1/2
• More localized effects
![Page 35: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/35.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
35
![Page 36: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/36.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
36
![Page 37: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/37.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
37
![Page 38: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/38.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
38
General functions of Parasympathetic system
• Protecting, resting and compensating bodily organs:– decreased heart rate– salivation and digestion– bowel and bladder emptying– papillary constriction
![Page 39: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/39.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
39
PARASYMPATHETIC SUMMARY ACTIONS
• short-term control– ACh is quickly destroyed
• gastrointestinal tone
• paradoxical fear reaction– Paradoxical fear reaction occurs when there is no escape route
or no way to win• massive activation of the Parasympathetic
system• loss of control over urination or defecation
![Page 40: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/40.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
40
Sympathetic System Neurons
• The site of cell body of preganglionic neurons :– Intermediolateral
column T1 – L2
• The site of cell body of postganglionic neurons:– paravertebral ganglia
in sympathetic chain– prevertebral ganglia
near origins of celiac and mesenteric arteries
![Page 41: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/41.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
41
Parasympathetic Preganglionic Neurons
• The sites of cell body of Cranial Preganglionic neurons
• They are found in 4 locations– Edinger-Westphal-III– Sup salivatory nuc-VII– Inf salivatory nuc-IX– Dorsal nuc vagus &– Uppermost part of nuclus
ambiguus-X
• The sites of cell body of Pelvic Preganglionic neurons :
• S2, S3, S4– Project to terminal
ganglia in colon, rectum, bladder, prostate & vaginal glands, & erectile tissue of the penis and clitoris
![Page 42: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/42.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
42
Parasympathetic Postganglionic Neurons
• The sites of cell body of Cranial Postganglionic neurons:– Ciliary ganglion-III– Pterygopalatine &
Submandibular gang-VII
– Otic gang-IX– The wall of thoracic,
abdominal viscerae
• The sites of cell body of Pelvic Postganglionic neurons:– The wall of pelvic
viscerae
![Page 43: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/43.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
43
![Page 44: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/44.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
44
Heart Force , Rate @
![Page 45: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/45.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
45
intermediolateral Column T12-L2I
Uterus (Contraction )*
![Page 46: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/46.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
46
![Page 47: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/47.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
47
![Page 48: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/48.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
48
![Page 49: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/49.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
49
![Page 50: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/50.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
50
![Page 51: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/51.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
51
![Page 52: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/52.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
52
![Page 53: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/53.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
53
![Page 54: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/54.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
54
![Page 55: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/55.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
55
Comprehensive table of Autonomic system
• Digestive system
• Heart
• lung
• Kidney
• Eye
• Genital
![Page 56: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/56.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
Sciences Department
56
![Page 57: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/57.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
57
THE ENDTHE END
![Page 58: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/58.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
58
![Page 59: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/59.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
59
![Page 60: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/60.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
60
![Page 61: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/61.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
61
Sympathetic Parasympathetic Division DivisionUMN
LMN
SomaticNerve
![Page 62: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/62.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
62
Receptors of the ANSNamed after the nerve type that innervates them
Cholinergic Receptors:
The receptors on which Ach acts
NicotinicNM
NN
MuscarinicM1 – 15
Adrenergic Receptors:
The receptors on which NEP and EP act
αα1
α2
ßß1
ß2
DD1D2
![Page 63: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/63.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
63
Cholinergic RECEPTORS …
1. Nicotinic :Nicotine• The toxin obtained from tobacco
leaves which activates these receptors and always has a stimulatory action
2. Muscarinic– Muscarine
• The poison from a mushroom which activates these receptors at the effector site
![Page 64: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/64.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
64
Cholinergic RECEPTORS …
Kinds of nicotinic cholinoreceptors : ACh receptors on the adrenal
medulla ACh receptors on the
postganglionic neuron at the synapse between pre- and postganglionic neurons
ACh receptors on skeletal muscle
Muscarinic cholinoreceptor can be stimulatory or inhibitory
![Page 65: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/65.jpg)
1390 Isfahan Medical Faculty, Biomedical Sciences Department
65
ADRENERGIC RECEPTORS
alpha-1 – excitation (most common alpha)
alpha-2 – inhibition
beta-1 -- excitation beta-2 – inhibition (most common beta)
![Page 66: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/66.jpg)
SYMPATHETIC NERVOUS SYSTEM
• Prepares body to deal with stress– Fight or flight response
• Neurotransmitters are epinephrine and norepinephrine– Chemical substances that facilitate
excitation or inhibition of target cells
1390 Isfahan Medical Faculty, Biomedical Sciences Department
![Page 67: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/67.jpg)
• A drug that stimulates the sympathetic nervous system is known as a sympathomimetic or adrenergic agent
• A drug that inhibits the sympathetic nervous system is called a sympatholytic or anti-adrenergic agent
• Ex. Propanolol ( beta blocker )
1390 Isfahan Medical Faculty, Biomedical Sciences Department
![Page 68: Sjldllds ;l;sf’;’;s بسم الله الرحمن الرحیم 1390 1 Isfahan Medical Faculty, Biomedical Sciences Department.](https://reader036.fdocuments.net/reader036/viewer/2022062500/5697c0131a28abf838ccc9e1/html5/thumbnails/68.jpg)
PARASYMPATHETIC NERVOUS SYSTEM
• Controls vegetative functions– Constriction of pupils, slowing of heart rate,
constriction of bronchioles, etc.• Neurotransmitter is Acetylcholine• A drug that stimulates the system is called a
Parasympathomimetic or cholinergic drug– Eg. Prostigmine
• A drug that blocks or inhibits the system is called a Parasympatholytic or anticholinergic drug– Eg. Atropine
1390 Isfahan Medical Faculty, Biomedical Sciences Department