Size Optimization of YAG _ Final
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Transcript of Size Optimization of YAG _ Final
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Alejandro Cota
![Page 2: Size Optimization of YAG _ Final](https://reader033.fdocuments.net/reader033/viewer/2022042600/5877c5001a28ab39588b55f1/html5/thumbnails/2.jpg)
http://www.mesotheliomaguide.com/wp-content/uploads/2014/05/PhotodynamicTherapy.png
Procedure:
• Intravenous insertion of
anticancer nano-drug
• Irradiate the tumor site
• Drug is released and the
tumor is targeted
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Scintillator Ionizing
radiation Photo-
luminescence
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Source: http://www.uspharmacist.com/content/s/197/c/33020/
• Larger than 10 nm
to avoid first-pass
elimination in the
kidney
• Smaller than 150 to
200 nm to avoid
clearance in the
liver and spleen
![Page 5: Size Optimization of YAG _ Final](https://reader033.fdocuments.net/reader033/viewer/2022042600/5877c5001a28ab39588b55f1/html5/thumbnails/5.jpg)
YAG:Pr
Alumina
Praseodymium
Yttrium
Methanol
Mix until solvent evaporates.
0
200
400
600
800
1000
1200
0 1 2 3 4 5 6 7
Tem
pera
ture
°C
Calcination Profiles
Time (hours)
~ 2 days
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Filters
White: 450nm
Yellow: 450nm
Green: 220nm
Blue: 200nm
![Page 7: Size Optimization of YAG _ Final](https://reader033.fdocuments.net/reader033/viewer/2022042600/5877c5001a28ab39588b55f1/html5/thumbnails/7.jpg)
Filters
White: 450nm
Green: 220nm
Filters
Yellow: 450nm
Green: 220nm
![Page 8: Size Optimization of YAG _ Final](https://reader033.fdocuments.net/reader033/viewer/2022042600/5877c5001a28ab39588b55f1/html5/thumbnails/8.jpg)
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Scale:100nm
Pictures taken by:
Dr. Novitskaya
![Page 10: Size Optimization of YAG _ Final](https://reader033.fdocuments.net/reader033/viewer/2022042600/5877c5001a28ab39588b55f1/html5/thumbnails/10.jpg)
Scale: 50nm
Pictures taken by:
Dr. Novitskaya
![Page 11: Size Optimization of YAG _ Final](https://reader033.fdocuments.net/reader033/viewer/2022042600/5877c5001a28ab39588b55f1/html5/thumbnails/11.jpg)
YAG:Pr
Aluminum
Praseodymium Yttrium
Carbohydrazide Fuel
Water
Combust at T = 500 °C
0
200
400
600
800
1000
1200
0 1 2 3 4 5 6 7
Tem
pera
ture
°C
Calcination Profiles
Time (hours)
~50 min
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Sol-Gel Synthesis
Combustion Synthesis
Impurities
2ϴ
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![Page 14: Size Optimization of YAG _ Final](https://reader033.fdocuments.net/reader033/viewer/2022042600/5877c5001a28ab39588b55f1/html5/thumbnails/14.jpg)
Pictures taken by: Dr. Novitskaya
Scale: 100nm
![Page 15: Size Optimization of YAG _ Final](https://reader033.fdocuments.net/reader033/viewer/2022042600/5877c5001a28ab39588b55f1/html5/thumbnails/15.jpg)
Pictures taken by: Ajay Sapre
![Page 16: Size Optimization of YAG _ Final](https://reader033.fdocuments.net/reader033/viewer/2022042600/5877c5001a28ab39588b55f1/html5/thumbnails/16.jpg)
Pictures taken by:
Dr. Novitskaya
![Page 17: Size Optimization of YAG _ Final](https://reader033.fdocuments.net/reader033/viewer/2022042600/5877c5001a28ab39588b55f1/html5/thumbnails/17.jpg)