7/27/2019 SINTESA OBAT.pptx

http://slidepdf.com/reader/full/sintesa-obatpptx 1/8

SINTESA OBAT

7/27/2019 SINTESA OBAT.pptx

http://slidepdf.com/reader/full/sintesa-obatpptx 2/8

SINTESA ASPIRINAnalisis Diskoneksi

7/27/2019 SINTESA OBAT.pptx

http://slidepdf.com/reader/full/sintesa-obatpptx 3/8

SINTESA

7/27/2019 SINTESA OBAT.pptx

http://slidepdf.com/reader/full/sintesa-obatpptx 4/8

-Mekanisme Reaksi

7/27/2019 SINTESA OBAT.pptx

http://slidepdf.com/reader/full/sintesa-obatpptx 5/8

SINTESA PHENOL

Analisis Diskoneksi

7/27/2019 SINTESA OBAT.pptx

http://slidepdf.com/reader/full/sintesa-obatpptx 6/8

SINTESA

 N   N

Garam Diazonium

OH NH2

 NaNO2

H2SO4 5°C

H2O

AnilinPhenolum

7/27/2019 SINTESA OBAT.pptx

http://slidepdf.com/reader/full/sintesa-obatpptx 7/8

  Mekanisme Reaksi

2HO N O H

O N O

H

H

- H2O N O

ion nitrosonium

 N

H

H

 N O N

H

H

 N O

7/27/2019 SINTESA OBAT.pptx

http://slidepdf.com/reader/full/sintesa-obatpptx 8/8

 N N O H  N N O H

H H

 N  N OH

H

- H2O

 N   N

H

 N   N

H O   H- N2

>5° C

O

H

H

H

- H

OH

H

OH Fenol (MT)