Semiconductor Solutions for the Healthcare Challenge...1994 2000 2010 2025 In 2025 7.3% of the...
Transcript of Semiconductor Solutions for the Healthcare Challenge...1994 2000 2010 2025 In 2025 7.3% of the...
Semiconductor Solutions for the Healthcare Challenge
Werner Neumann
electronica Medical Forum
November 11, 2008
Sept 2008 p.2Werner Neumann
STMicroelectronics Solutions for Healthcare November 2008 - p.2
Healthcare – A Challenge
Source: IDF Diabetes Atlas 2006, Wikipedia, Spectaris 2008
• Health cost in Germany 2006: 148B€
• Potential to save 2.7B€ with modern medical electronics
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1994 2000 2010 2025
In 2025 7.3% of the worlds population might suffer from diabetes
Aging pyramid for Germany, Forecast for 2050
Diabetes Impaired Million people ww
Sept 2008 p.3Werner Neumann
STMicroelectronics Solutions for Healthcare November 2008 - p.3
STMicroelectronics’ 3 Pillars in Healthcare
Mass Market ApplicationApproach
• Products ready now
• Development Tools
• Short Time-To-Market
Healthcare Key CTM
Partnership
Develop new dedicated
products and technologies
Government programs,Consortia,Universities
Technology,Investment into
the future
Sept 2008 p.4Werner Neumann
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ST Healthcare Solutions
Hearing Aid, Assembly Tech.
Patient Health Records
Tele-monitoring,Home Health
Imaging
Home HealthImplantsDisposable Healthcare
MolecularDiagnostic
Driving ApplicationsEmerging Applications
Sept 2008 p.5Werner Neumann
STMicroelectronics Solutions for Healthcare November 2008 - p.5
ST Healthcare Solutions
Molecular Diagnostic
MolecularDiagnostic
• Medical Diagnostics – Point of Care
• Environmental Control – Air/Water
• Agro-Industrial Control – Genetically Modified Objects
Sept 2008 p.6Werner Neumann
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ST In-Check™ Platform
Sept 2008 p.7Werner Neumann
STMicroelectronics Solutions for Healthcare November 2008 - p.7
ST Platform Approach To Biotech Market
Expert biologists
Big Central Lab
Automation
Hospital LabIntegration
Quantification
Miniaturization - Automation - Reliability
User friendly
Low cost
Fast
Portable
Sept 2008 p.8Werner Neumann
STMicroelectronics Solutions for Healthcare November 2008 - p.8
In-Check™ Platform: Main Elements
Biochip Core
Reader
Software platform
Thermal Control System
Pathogen A
Pathogen B
Pathogen C
Marker A
Marker B
Biological Content From ST partners
Sept 2008 p.9Werner Neumann
STMicroelectronics Solutions for Healthcare November 2008 - p.9
Core Silicon Chip
Ta/Au electrodes
Thermal Sensors - Al/Si/Cu
Fluidic Inlets - Glass
Buried Channels
Surface Channels - Dry resist
Microarray Detection Area
Sept 2008 p.10Werner Neumann
STMicroelectronics Solutions for Healthcare November 2008 - p.10
Concept & Application
Analysis Time: 1- 2 hours
In-Check is designed as an open platform for fast and highly automated DNA analysis.
Example Screenshot
Sept 2008 p.11Werner Neumann
STMicroelectronics Solutions for Healthcare November 2008 - p.11
Insulin Nanopump™ in MEMS Technology
Disposable
Healthcare
Inlet valve
Pumping chamber
Outlet valveDetector
• Small, Precise, Safe
Sept 2008 p.12Werner Neumann
STMicroelectronics Solutions for Healthcare November 2008 - p.12
European Imaging Project: Megaframe
• Array of diodes in Geiger mode
• One million frames per second imaging
• Count of single photons with a timing resolution of 100ps.
• A new enabler for non-invasivediagnostics with big potential:
– Optical Coherence Tomography (OCT)
– Fluorescence Lifetime Analysis (FLIM)
– Blood glucose metering
– SpO2 Blood oxygen saturation level
– http://www.megaframe.eu
OCT skin analysis video
Sept 2008 p.13Werner Neumann
STMicroelectronics Solutions for Healthcare November 2008 - p.13
Technologies for Implantable Devices
1200V dice
3-D MEMS dice
IGBT
MEMS
HCMOS9 LP/ULL
Low Power CMOSUltra Low Leakage
0.13um CMOS
Selected Technologies
HVG8
High Voltage Gate
0.18um CMOS
High Voltage Switch
ECG Unit(ADC)
HV H-Bridge
HV Control
Switching
High Voltage
Capacitor
Capacitor ChargerControl
CircuitMemory Techno.
Power Management
Communication
MEMS Acce-
lerometer
IPAD Device Integration / Hybrids
Implants
Sept 2008 p.14Werner Neumann
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Solutions For Each Function
PortableHealthcare
• Glucose Meter
• Insulin Pump
• Blood Pressure
• Thermometer
• Fertility Tester
• Sensors
– MEMS accelerometer
– MEMS microphone
– MEMS technology enables implantable sensors
• Analysis
– Low Power Micro / DSP Functionality
– EEPROM Memory
– ADC, Analog Std. product and ASIC
– Power Management
– RF-ASIC/ZigBee/NFC
• Drug Delivery
– Insulin Nanopump
– MCU / Dual Core ASIC
Sept 2008 p.15Werner Neumann
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STM32 Low Power MCU
• ST provides software routines for faster Time-to-market:
• VDE Certified Firmware for STM32 Family according IEC60335 Type B, similar to SIL-2.
• 3DES/AES Encryption Libraries
Sept 2008 p.16Werner Neumann
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Motor Control Solutions
• Respirator
• Wheelchair
• Hospital Drug Delivery
• 8-bit: ST7FMC, 32-bit: STM32Power Electronics
• BLDC, 3ph-Induction, PMSM Motors
• Vector / Field Oriented Control
– FIR and IIR filters, PID controller
– Motor control dedicated PWM peripheral
– Dual 12-bit ADC converter, 1 MS/s with synchronization capabilities
– All libraries available now
• Examples:
– Ultra silent drive
– Voice encoding / decoding for commands
– Fast Fourier Transformation
Sept 2008 p.17Werner Neumann
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STM32-EVALBoard, Small Packages
• Starter Kits from ST, IAR, Keil, Hitex
• Demos for USB, CAN, SD Card etc…available from www.st.com/mcu
• Hotline support
• Ultra small packages available
Sept 2008 p.18Werner Neumann
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EEPROM
• Any Communication interface in any Density:– I2C from 1 Kb to 1 Mb
– SPI from 1 Kb to 1 Mb
– Microwire from 1 Kb to 16 Kb
• On top of standard packages (SO8, SSOP8):– MLP 2x3 up to 128 Kb
– WLCSP for the smallest high density EEPROM in the world
• ST # 1 in EEPROM
• Special Service: custom trimming of key parameter
Sept 2008 p.19Werner Neumann
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Tele-Monitoring: ZigBee, NFC
To continuously monitor variations in:
• Temperature
• Heart rate
• Blood oxygenation
• Respiratory rate
ZigBee SN250 module
Tele-Monitoring,Home Health
Sept 2008 p.20Werner Neumann
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Miniaturized Packages
Stack Die Through Silicon Via
WLCSPWafer Level Chip Scale Package
Bumped die
SIP System in Package
Down to 400µm pitch
µQFN
Assembly Technology
Sept 2008 p.21Werner Neumann
STMicroelectronics Solutions for Healthcare November 2008 - p.21
New ST Micropower Operation Amplifier for Healthcare Analog Front Ends
• Market Leader
– Over 2 Billion units of analog mixed products shipped in 2007
– 6% Market Share WW in 2007
• New Product:
– High merit factor: 5V, 60µA/890kHz
– Low Vio: 1mV max
– Very narrow dispersion of Icc and AC parameters
– Micro Packages: SC70-5, SOT23-8, MSO8-10
• Available in Q1/2009
Vdd
Vss
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NEW
NEW
NEW
NEW
Sept 2008 p.22Werner Neumann
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Summary
• ST is taking care
– Long term research
– Strong partnerships with market leaders
– State of the art products
– Radical innovative technology
• Products are available now
• Demoboards and support hotline for fast development
On-Chip Cell Sorting