SDPpred: a method for identification of amino acid residues that determine differences in functional...

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Positions that account for specificity Assignment of specificity to new proteins Experiment Testing on families that include proteins with resolved 3D structure SDPpred Description of specificity groups : Group А: No. 1-10,13… Group В: No.12, 14-16… Group С: No … … Q9KDW MSPFLGEVIGTMILIILGGGVVAGVVLKGTK Q8Y6Z1 ----MIDTSLATQFLGEVIGTAILIILGAGVVAGVSLKRSK Q97JG MTIFFAELVGTLLLILLGDGVVANVVLKNSK GLPF_ECOLI MSQT---STLKGQCIAEFLGTGLLIFFGVGCVA--ALKVAG Q8ZJK5 MSQTA-SSTLKGQCIAEFLGTGLLIFFGAGCVA--ALKLAG GLPF_HAEIN MDKS-----LKANCIGEFLGTALLIFFGVGCVA—-ALKVAG GLPF_PSEAE MTTAAPTPSLFGQCLAEFLGTALLIFFGTGCVA--ALKVAG AQPZ_BRUME MLNKLSAEFFGTFWLVFGGCGSAILAA--AFP Q92NM MFRKLSVEFLGTFWLVLGGCGSAVLAA--AFP Q8UJW MGRKLLAEFFGTFWLVFGGCGSAVFAA--AFP AQPZ_ECOLI MFRKLAAECFGTFWLVFGGCGSAVLAA--GFP Alignment ?

On the Distribution of Quadratic Residues and Non-residues ... · On the Distribution of Quadratic Residues and Non-residues Modulo Composite Integers and Applications to Cryptography

On the Distribution of Quadratic Residues and Non-residues ... · On the Distribution of Quadratic Residues and Non-residues Modulo Composite Integers and Applications to Cryptography

1 Roles of N-Terminal Region Residues Lys11, Arg13 and ...urdesai/papers/K11_paper.pdf · antithrombin to which the heparin pentasaccharide binds with high affinity and specificity

1 Roles of N-Terminal Region Residues Lys11, Arg13 and ...urdesai/papers/K11_paper.pdf · antithrombin to which the heparin pentasaccharide binds with high affinity and specificity

The conformation of acetylcholine at its target site in ...bonding to the nicotinic acetylcholine receptor residues Y116 and T119 that are homologous to L112 in the soluble acetylcholine-binding

The conformation of acetylcholine at its target site in ...bonding to the nicotinic acetylcholine receptor residues Y116 and T119 that are homologous to L112 in the soluble acetylcholine-binding

CAT’s views on classification of ATMPs: homologous use · Organ transplantation BMT Pancreatic iPSc islest Bone marrow in bone healing CD34 in myocardium . 6 Homologous vs/Non homologous

CAT’s views on classification of ATMPs: homologous use · Organ transplantation BMT Pancreatic iPSc islest Bone marrow in bone healing CD34 in myocardium . 6 Homologous vs/Non homologous

Localization of Residues That Confer Antibody Binding Specificity ...

Localization of Residues That Confer Antibody Binding Specificity ...

Case Study: Sporulation (c. 2010) Sporulation Initiation ...durand/Phylogenetics/2017/Lectures/Phylogeneti… · Recall: Specificity residues control signal fidelity 54 Antibiotic

Case Study: Sporulation (c. 2010) Sporulation Initiation ...durand/Phylogenetics/2017/Lectures/Phylogeneti… · Recall: Specificity residues control signal fidelity 54 Antibiotic

Homologous and Site-Specific Recombination

Homologous and Site-Specific Recombination

protein homologous to arthropod hemocyaniin

protein homologous to arthropod hemocyaniin

Mechanism of Eukaryotic Homologous Recombination

Mechanism of Eukaryotic Homologous Recombination

Intratumor heterogeneity and homologous recombination ...

Intratumor heterogeneity and homologous recombination ...

OPEN specifiCITY - Shift

OPEN specifiCITY - Shift

Site-Specificity Powerpoint

Site-Specificity Powerpoint

Summary of Homologous Series

Summary of Homologous Series

Homologous Series Members

Homologous Series Members

Non Homologous End Joining. Homologous Recombination Non Homologous End Joining.

Non Homologous End Joining. Homologous Recombination Non Homologous End Joining.

Homologous genes

Homologous genes

PRINCIPLES OF TRAINING. Specificity Specificity Overload Overload Progression Progression Reversibility Reversibility.

PRINCIPLES OF TRAINING. Specificity Specificity Overload Overload Progression Progression Reversibility Reversibility.

Levels of Specificity

Levels of Specificity

DNA break repair by homologous recombination Homologous Recombination · 2007-01-01 · Homologous Recombination target replaced with donor DNA sequence ! induced break ! donor DNA

DNA break repair by homologous recombination Homologous Recombination · 2007-01-01 · Homologous Recombination target replaced with donor DNA sequence ! induced break ! donor DNA

Sensitivity and Specificity

Sensitivity and Specificity