ScIENCE...ISSN0036-8075 5 JUNE1992 VOLUME256 NUMBER5062 AMERICAN ASSOCIATIONFORTHE ADVANCEMENTOF...

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ISSN 0036-8075 5 JUNE 1992 VOLUME 256 NUMBER 5062 AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE 1 3969 1 402, =% 1416 & 1420 RNA makes peptlde bonds and that s not all NEWS & COMMENT Furor at Lyme Disease Conference California Rides Its Own Bi-Cycle Mission Impossible: Saving All Endangered Species Errant HIV Strain Renders Test Virus Stock Useless r 1384 1386 1387 NASA Researchers Protest DOE Turnoff 1388 Panel Clears Needleman of Misconduct 1389 Institute of Medicine Elects New Members 1389 WS........ Scoring a Technical Knockout in Mice r 1392 Researchers Wrestle With Concerns Over Cost and Access Did an Asteroid Leave Its Mark in 1395 Montana Bones? Finding RNA Makes Proteins Gives 1396 'RNA World' a Big Boost Gammas From Heaven 1397 1 392 Knockout mice find & favor with 1 448 biologists PERSPECTIVES New Horizons for RNA Catalysis N. R. Pace On the Other Hand ... G. A. Petsko r 1402 F 1403 ARTICLES Crust Formation and Plate Motion in the Early Archean A. Kroner and P. W. Layer Human Organ Transplantation: Background and Consequences J. E. Murray 1405 1411 DEPARTMENTS THIS WEEK IN SCIENCE EDITORIAL Economic Impact Report 1371 1373 LETTERS 1378 The Smithsonian and Sheep Hunting: R. S. Hoffmann; E. Marshall * European Science: H. W. Mewes, S. Oliver, A. Goffeau; A. Anderson; A. A. Travers, A. Anderson * NIH Leaks: J. Schneider * Fear of Butterflies: A. M. Shapiro - Math Teaching, K-12: Relevant Expertise: S. Mac Lane SCIENCESCOPE 1383 Needles shoot down ADAMHA reorganization, etc. RANDOM SAMPLES 1390 An OTA for Parliament * Parkinson's Progresse Birth Control for Animals, etc. BOOK REVIEWS 1464 A Space for Science, reviewed by D. Serwer * Some Other Books of Interest * Vignettes: Popular Images * Books Received PRODUCTS & MATERIALS 1467 .AAAS Board of Directors- .:Board of Reviewing Editors. Leon M. Lederman Retiring President, Chairman F. Sherwood Rowland President Eloise E. Clark President-elect Mary Ellen Avery Francisco J. Ayala Robert A. Frosch Florence P. Haseltine Alan Schriesheim Jean'ne M. Shreeve Chang-Lin Tien Warren M. Washington William T. Golden Treasurer Richard S. Nicholson Executive Officer John Abelson Frederick W. Alt Don L. Anderson Stephen J. Benkovic David E. Bloom Floyd E. Bloom Henry R. Bourne James J. Bull Kathryn Calame C. Thomas Caskey Dennis W. Choi John M. Coffin Bruce F. Eldridge Paul T. Englund Richard G. Fairbanks Douglas T. Fearon Harry A. Fozzard Victor R. Fuchs Theodore H. Geballe Margaret J. Geller John C. Gerhart Roger 1. M. Glass Stephen P. Goff Corey S. Goodman Stephen J. Gould Ira Herskowitz Eric F. Johnson Stephen M. Kosslyn Michael LaBarbera Charles S. Levings Ill Harvey F. Lodish Richard Losick Anthony R. Means Mortimer Mishkin Roger A. Nicoll William H. Orme-Johnson Ill Stuart L. Pimm Yeshayau Pocker Dennis A. Powers Ralph S. Quatrano V. Ramanathan Erkki Ruoslahti Ronald H. Schwartz Terrence J. Sejnowski Thomas A. Steitz Richard F. Thompson Robert T. N. Tjian Emil R. Unanue Geerat J. Vermeij Bert Vogelstein Harold Weintraub Zena Werb George M. Whitesides Owen N. Witte Keith Yamamoto SCIENCE * VOL. 256 * 5 JUNE 1992 ScIENCE 1368

Transcript of ScIENCE...ISSN0036-8075 5 JUNE1992 VOLUME256 NUMBER5062 AMERICAN ASSOCIATIONFORTHE ADVANCEMENTOF...

  • ISSN 0036-80755 JUNE 1992VOLUME 256NUMBER 5062

    AMERICANASSOCIATION FOR THEADVANCEMENT OFSCIENCE

    1 3969 1 402, =%1416 & 1420RNA makes peptlde bonds

    and that s not all

    NEWS & COMMENTFuror at Lyme Disease ConferenceCalifornia Rides Its Own Bi-Cycle

    Mission Impossible: Saving AllEndangered Species

    Errant HIV Strain Renders Test VirusStock Useless

    r 1384

    1386

    1387

    NASA Researchers Protest DOE Turnoff 1388

    Panel Clears Needleman of Misconduct 1389

    Institute of Medicine Elects New Members 1389

    WS........

    Scoring a Technical Knockout in Mice r 1392Researchers Wrestle With Concerns OverCost and Access

    Did an Asteroid Leave Its Mark in 1395Montana Bones?

    Finding RNA Makes Proteins Gives 1396'RNA World' a Big Boost

    Gammas From Heaven 1397

    1 392 Knockoutmice find

    & favor with

    1 448 biologists

    PERSPECTIVESNew Horizons for RNA CatalysisN. R. Pace

    On the Other Hand ...G. A. Petsko

    r 1402

    F 1403

    ARTICLESCrust Formation and Plate Motion in theEarly ArcheanA. Kroner and P. W. Layer

    Human Organ Transplantation:Background and Consequences

    J. E. Murray

    1405

    1411

    DEPARTMENTSTHIS WEEK IN SCIENCE

    EDITORIALEconomic Impact Report

    1371

    1373

    LETTERS 1378The Smithsonian and Sheep Hunting: R. S.Hoffmann; E. Marshall * European Science:H. W. Mewes, S. Oliver, A. Goffeau; A. Anderson;A. A. Travers, A. Anderson * NIH Leaks:J. Schneider * Fear of Butterflies: A. M. Shapiro -Math Teaching, K-12: Relevant Expertise:S. Mac Lane

    SCIENCESCOPE 1383Needles shoot down ADAMHA reorganization, etc.

    RANDOM SAMPLES 1390An OTA for Parliament * Parkinson's ProgresseBirth Control for Animals, etc.

    BOOK REVIEWS 1464A Space for Science, reviewed by D. Serwer * SomeOther Books of Interest * Vignettes: Popular Images* Books Received

    PRODUCTS & MATERIALS 1467

    .AAAS Board of Directors- .:Board of Reviewing Editors.

    Leon M. LedermanRetiring President,Chairman

    F. Sherwood RowlandPresident

    Eloise E. ClarkPresident-elect

    Mary Ellen AveryFrancisco J. AyalaRobert A. Frosch

    Florence P. HaseltineAlan SchriesheimJean'ne M. ShreeveChang-Lin TienWarren M. Washington

    William T. GoldenTreasurer

    Richard S. NicholsonExecutive Officer

    John AbelsonFrederick W. AltDon L. AndersonStephen J. BenkovicDavid E. BloomFloyd E. BloomHenry R. BourneJames J. BullKathryn CalameC. Thomas CaskeyDennis W. Choi

    John M. CoffinBruce F. EldridgePaul T. EnglundRichard G. FairbanksDouglas T. FearonHarry A. FozzardVictor R. FuchsTheodore H. GeballeMargaret J. GellerJohn C. GerhartRoger 1. M. Glass

    Stephen P. GoffCorey S. GoodmanStephen J. GouldIra HerskowitzEric F. JohnsonStephen M. KosslynMichael LaBarberaCharles S. Levings IllHarvey F. LodishRichard LosickAnthony R. Means

    Mortimer MishkinRoger A. NicollWilliam H. Orme-Johnson IllStuart L. PimmYeshayau PockerDennis A. PowersRalph S. QuatranoV. RamanathanErkki RuoslahtiRonald H. SchwartzTerrence J. Sejnowski

    Thomas A. SteitzRichard F. ThompsonRobert T. N. TjianEmil R. UnanueGeerat J. VermeijBert VogelsteinHarold WeintraubZena WerbGeorge M. WhitesidesOwen N. WitteKeith Yamamoto

    SCIENCE * VOL. 256 * 5 JUNE 1992

    ScIENCE

    1368