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SCHOOL OF BIOTECHNOLOGY

Devi Ahilya Vishwavidyalaya Khandwa Road, Indore 452001, INDIA

Departmental Profile 2019-2020

For Contact: Dr. Anjana Jajoo

Head, School of Biotechnology

Devi Ahilya Vishwavidyalaya

Khandwa Road, INDORE 452001, INDIA.

Tel: +91-731 2470373.

E-mail: ajheadsbt@gmail.com, head.biotech@dauniv.ac.in, biotechdavv@gmail.com

Website: www.biotech.dauniv.ac.in/

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About the Department:

The School of Biotechnology was established in 1991 at Devi Ahilya Vishwa Vidyalaya, Indore

with financial assistance from Department of Biotechnology, Ministry of Science & Technology,

Government of India, New Delhi. From 1990 to 1997 the School of Biotechnology was

running its classes in the first floor of Vigyan Bhawan at Takshshila Campus of the

University. In 1997 the School moved to its own Biotechnology Building in the same campus.

The School of Biotechnology has its own double storied building with a total surface area of

about 12000 + 8000 Sq. feet. The School has sophisticated laboratory facilities for Enzyme

Technology, Genetic Engineering, Microbiology, Plant Tissue Culture, Biochemical Engineering

and Environmental Biotechnology. School of Biotechnology is also having Bioinformatics Sub-

Centre, which is involved in high-level research work and software development in the

field of Bioinformatics.

We offer M.Sc. as well as Ph.D. in Biotechnology.

Enrollment of Students in M.Sc. Biotechnology

YEAR M.Sc. I YEAR M.Sc. II YEAR 1991-1992 09 - 1992-1993 07 09

1993-1994 14 07

1994-1995 15 14

1995-1996 12 15

1996-1997 09 12

1997-1998 09 09

1998-1999 12 09

1999-2000 13 12

2000-2001 16 13

2001-2002 15 16

2002-2003 15 15

2003-2004 14 15

2004-2005 17 14

2005-2006 14 17

2006-2007 14 14

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2007-2008 16 14

2008-2009 15 16

2009-2010 09 15

2010-2011 16 09

2011-2012 14 11

2012-2013 15 14

2013-2014 11 15

2014-2015 12 11

2015-2016 11 12

2016-2017 15 10

2017-2018 15 14

2018-2019 11 12

2019-2020 16 11 Sanctioned student strength from DBT is 16* (09 General, 04 OBC, 02 SC and 01 ST) from 2009-10 session. *This number includes OBC category seats as per decision of the Honorable Supreme Court. The number in the above table also includes 05 Industry Sponsored seats approved by the DBT. From the academic session 2007-08 University started 2 years M.Sc. program in Genetic Engineering. It is a Self Finance program.

Enrollment of Students in M.Sc. Genetic Engineering

YEAR M.Sc. I YEAR M.Sc. II YEAR

2007-2008 21 --

2008-2009 17 17 2009-2010 18 14 2010-2011 24 16 2011-2012 23 22

2012-2013 12 21 2013-2014 07 12

2014-2015 14 07 2015-2016 09 14 2016-2017 06 09

2017-2018 02 05

2018-2019 13 01

2019-2020 23 13

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From the academic session 2009-10 University started 2 years M.Sc. program in Bioinformatics. It is a Self Finance program.

Enrollment of Students in M.Sc. Bioinformatics

Sanctioned student strength for M.Sc. Genetic Engineering & M.Sc. Bioinformatics course is 24.

Eligibility for Admission:

A Bachelors degree under 10+2+3 pattern of education in Physical, Biological,

Agricultural, Veterinary, Fishery Sciences, Pharmacy, Engineering/Technology, 4-years B.S.(Physician Assistance) course or Medicine (MBBS) or B.D.S. with at least 55% marks.

Selection Procedure: JNU conducts a combined entrance examination for admission to two year M.Sc. program

in Biotechnology for all the participating Universities. Selection is purely based on merit of the candidate in the entrance test and preferences for Universities indicated by him/her in the application form.

We also have five Industry sponsored seats for which eligibility criteria are same as

mentioned above for the merit seats. We conduct Combined Entrance Test (CET) for Industry sponsored seats.

We also conduct Combined Entrance Test (CET) for admission in M.Sc. Genetic Engineering & M.Sc. Bioinformatics.

YEAR M.Sc. I YEAR M.Sc. II YEAR

2009-2010 21 -- 2010-2011 24 19 2011-2012 22 21 2012-2013 09 19 2013-2014 09 09 2014-2015 06 09 2015-2016 08 05 2016-2017 07 04 2017-2018 04 06 2018-2019 11 04 2019-2020 06 06

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Faculty Member

Dr. Anjana Jajoo

Professor & Head

Dr. Hamendra Singh

Parmar

Senior Lecturer

Dr. Anil Kumar

Professor (Retired)

Ms. Shweta Nakul

Contractual Teacher

Person involved in teaching

Ms. Nikita Chordia

Information Officer

Mr. Priyesh Hardia

Computer Programmer

Guest Faculty

1. Dr. Venuka Goyal 2. Mr. Chetan Awasthi 3. Ms. Swati Patidar

Library:

We have a fully functional Departmental library containing ~ 2500 books on all branches of

Biotechnology. We have subscription to Nature, Journal of Bioscience & Bioengineering,

Journal of Genetics, Journal of Biological Chemistry (on line) and Journal of Cell & Tissue

Research. Besides, we have access to the Scientific, Technical and Scholarly content of 908

Journal Wiley titles as a valuable tool to facilitate the research & academic needs, under UGC-

INFONET Digital Library Consortium managed by the INFLIBNET Centre.

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Equipments:

1. Micro plate Reader 2. CO2 Incubator

3. Trinocular research microscope RH-81 TRH 4. Microcentrifuse MC03 micro

5. UV-VIS Spectrophotometer (2 in no.

Shimadzu Model 1700 A & 160 A). 6. Sorvall 5B Super Speed Centrifuge.

7. Liquid chromatography system. 8. Liquid chromatography system.

9. Ice flaking machine. 10. Gel drying system.

11. Gel drying system. 12. ‘Labline’ Environmental orbital shaker.

13. Deep freezer -90C. 14. Deep freezer -20C, (2 in No.).

15. Vacuum oven. 16. Microbiological incubator (2 in No.).

17. Cold Room. 18. Remi C-24 Cooling Centrifuge.

19. Electrophoresis System. 20. Colorimeter.

21. Autoclave (3 in No.). 22. Laminar flow (2 in No.).

23. Digital balance (4 in No.). 24. Thermocycler (2 in No. Eppendroff,

Germany & Amplitron, France).

25. Gel documentation system. 26. UV Transilluminator.

27. Ultrasonicator. 28. Temperature controlled ovens (3 in no.).

29. Bacteriological Incubators (2 in no.). 30. Remi Make Orbital Incubator Shaker.

31. Plant Tissue Culture Facility. 32. ‘LABHOSP’ Rotary Shaking Machine (LHC-38 model).

33. ELISA Plate reader with accessories. 34. Fermenter.

35. HPLC. 36. Light microscope.

37. Flourescent Microscope.

In addition many mini equipment(s) are also available in the department. Our M.Sc. and Ph.D. Biotechnology students are using all the equipment(s). The students of other Departments are allowed to use our equipment (s) on request.

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M.Sc. General Biotechnology (BT5A) Syllabus SEMESTER – I

Course Code Title Credits

BT MB 501 Biochemistry (Core) 03 BT MB 511 Cell & Developmental Biology (Core) 03 BT MB 521 Molecular Biology (Core) 03 BT MB 531 Analytical Techniques (Core) 03 BT MB 541 Computer Application, Bioinformatics & Biostatistics (Core) 03 BT MB 551 Seminar & Communication Skills (Soft Skill Development) 01 BT MB 561 Practical 06

Comprehensive Viva-Voce 04 Total 26

SEMESTER – II

Course Code Title Credits

BT MB 502 Immunology (Core) 03 BT MB 512 Genetics (Core) 03 BT MB 522 Genetic Engineering (Core) 03 BT MB 532 Enzyme & Enzyme Technology (Core) 03 BT MB 542 Environmental Biotechnology (Generic Elective) 03 BT MB 552 Genomics & Proteomics (Discipline Centric Elective) 1.5 BT MB 562 Protein Engineering (Discipline Centric Elective) 1.5 BT MB 572 Cancer Genetics (Discipline Centric Elective) 1.5 BT MB 582 Seminar/ Research Skill Development (Soft Skills) 02 BT MB 592 Practical 08

Comprehensive Viva - Voce 04 Total 32

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SEMESTER – III Course Code Title Credits BT MB 601 Bioprocess Engineering & Technology (Core) 03 BT MB 611 Plant Biotechnology (Core) 03 BT MB 621 Microbiology and Industrial Applications (Core) 03 BT MB 631 IPR & Biosafety (Generic Elective) 03 BT MB 641 Metabolic Engineering (Skill Enhancement) 03 BT MB 651 Animal Tissue Culture (Discipline Centric Elective) 1.5 BT MB 661a Stem Cell Biology (Discipline Centric Elective) 1.5 BT MB 661b Pharmacogenomics (Discipline Centric Elective) 1.5 BT MB 671 Seminar (Soft Skills) 02 BT MB 681 Research Proposal Writing Skills (Soft Skills) 01 BT MB 691 Practical 08

Comprehensive Viva - Voce 04 Total 33

SEMESTER – IV Course Code Title Credits BT MB 602 Project Work 12 BT MB 612 Seminar (Topic other then the dissertation work) 02

Comprehensive viva-voce 04 Total 18

Total Credits............................................................................................109 GRADING SYSTEM: Our University follows the grading system of evaluation. The percentage of mark and their equivalent grades are as mentioned below:

Letter Grade Grade Point Description Range of Marks

(%) O 10 Outstanding 90-100

A+ 9 Excellent 80-89 A 8 Very Good 70-79 B+ 7 Good 60-69

B 6 Above Average 50-59

C 5 Average 40-49 P 4 Pass 35-39 F 0 Fail 0-34

Ab 0 Absent Absent

Percentage marks = CGPA (GGPA) X 10

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In general, Ordinance No. 31 is followed for the examination system.

Project: Project will be based upon research and actual bench work. It will begin from III semester and will continue through the IV semester. Project report will be submitted at the end of IV semester and evaluated.

Student Seminar: Each student under the supervision of a faculty member will deliver a comprehensive seminar, which will be evaluated. The topic normally will be from an emerging area of Modern Biology, Bio-medical science, Biotechnology or its applications.

Laboratory I, II, III, IV: Independent practicals will be held under each course. However, for examination purposes a single comprehensive 2-3 days practical is held for each semester, covering different courses offered during that semester. Practical training is organized as an exercise, rather than a simple demonstration. The students actually perform the experiments.

Assignments: Regular assignments are given to each student during the whole semester in each course. Assignments are relevant to the course content. All assignments are evaluated as

Internal Assessment.

Invited lectures from Eminent Researchers, Industrialists and others, on recent issues related to Bio-diversity, Bio-safety, intellectual Property Rights and Patent issues and Good laboratory and manufacturing practices are being organized.

We are planning to include the following areas as part of Student Seminar and

Assignments : 1. Proteomics, Functional Genomics and Therapeutic Genomics. 2. Topics on human genetics, genetic dissection of heritable diseases, detection of

associated mutations and diagnostics based on PCR. 3. Technologies being adapted for future applications like cloning of animals, with

capacity to produce human macromolecules. 4. Molecular medicine. 5. Stem cell therapeutics. 6. Nano biotechnology.

Detailed syllabus is available on our website, http://www.biotech.dauniv.ac.in/syllabus.php

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M.Sc. Genetic Engineering (BT5B) Syllabus

SEMESTER I

Course Code Title Credits BT GE 501 Biomolecules(Core) 03 BT GE 511 Cell Biology & Genetics(Core) 03 BT GE 521 Molecular Biology (Core) 03 BT G 531 Analytical Techniques(Core) 03

BT GE 541 Computer Applications in Biology & Bio-statistics (Core) 03 BT GE 551 Seminar & Communication Skills (Soft Skill Development) 01 BT GE 561 Practical 06

Comprehensive viva-voce 04

Total 26

SEMESTER II

Course Code Title Credits BT GE 502 Immunology (Core) 03 BT GE 512 Genetics (Core) 03 BT GE 522 Enzyme Technology (Skill Enhancement Course) 03 BT GE 532 Recombinant DNA Technology (Core) 03 BT GE 542 Bio-informatics (Discipline Centric Elective) 03 BT GE 552 Genomics & Proteomics (Discipline Centric Elective) 1.5 BT GE 562 Protein Engineering (Discipline Centric Elective) 1.5 BT GE 572 Environmental Biotechnology (Generic Elective) 03 BT GE 582 Seminar/ Research Skill Development (Soft Skills) 02 BT GE 592 Practical 08 BT GE 510 Comprehensive viva-voce 04

Total 32

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SEMESTER III

Course Code Title Credits BT GE 601 Metabolic Engineering (Core) 03 BT GE 611 Bioprocess Technology (Core) 03 BT GE 621 Agriculture Biotechnology (Core) 03 BT GE 631 Microbial Technology(Core) 03 BT GE 641 Biosafety, Bioethics and IPR (Generic Elective) 03 BT GE 651 Animal Tissue Culture (Discipline Centric Elective) 1.5 BT GE 661 Pharmacogenomics (Discipline Centric Elective) 1.5 BT GE 671 Stem Cell Biology (Discipline Centric Elective) 1.5 BT GE 681 Seminar (Soft Skills) 02 BT GE 691 Practical 08

Comprehensive viva-voce 04

Total 32

SEMESTER IV

Course Code Title Credits

BT GE 602 Project Work 12

BT GE 612 Comprehensive viva-voce 04

Total 16

Total Credits .………….……………………………………………106 Detailed syllabus is available on our website, http://www.biotech.dauniv.ac.in/syllabus.php

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M.Sc. Bioinformatics (BT5C) Syllabus

SEMESTER I

Course code

Title Credits

BT BI 501 Basic Mathematics (Core) 03 BT BI 511 Computer fundamentals and Biostatistics (Core) 03 BT BI 521 Bio-molecules (Core) 03 BT BI 531 Cell and Developmental Biology (Core) 03 BT BI 541 Programming in C/C++(Core) 03 BT BI 551 Molecular Biology (Core) 03 BT BI 561 Practical 06 BT BI 571 Seminar & Communication Skills (Soft Skill Development) 01

Comprehensive Viva Voce 04 Total credits 29

SEMESTER II

Course

code Title Credits

BT BI 502 Biological Databases and Data Analysis (Bioinformatics-I): (Core)

03

BT BI 512 Recombinant DNA Technology (Core) 03 BT BI 522 Design and Analysis of algorithms (Generic Elective) 03

BT BI 532 Internet & Web Based Programming (CGI PERL & HTML) (Skill Enhancement Course)

03

BT BI 542 Immunoinformatics (Discipline Centric Elective) 1.5 BT BI 552 Genomics & Proteomics (Discipline Centric Elective) 1.5 BT BI 562 Enzyme & Enzyme Technology (Discipline Centric Elective) 03 BT BI 572 Practical 08 BT BI 582 Seminars (Soft Skill Development) 02

Comprehensive Viva Voce 04 Total Credits 29

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SEMESTER III

Course

code Title Credits

BT BI 601 Machine Learning Techniques & CADD(Bioinformatics II) (Core) 03 BT BI 611 Structural Biology and Bioinformatics (Bioinformatics III) (Core) 03 BT BI 621 Database management System (Generic Elective) 03 BT BI 631 Java Programming (Core) 03

BT BI 641 Metabolic Engineering & System Biology (Discipline Centric Elective)

1.5

BT BI 651 Pharmacogenomics (Discipline Centric Elective) 1.5

BT BI 661 Microscopic Techniques For Image Processing (Discipline Centric Elective)

1.5

BT BI 671 Assignments/ Practical 08 BT BI 681 Seminar(Soft Skill Development) 02

Comprehensive Viva Voce 04 Total Credits 29

SEMESTER IV

Course code

Title Credits

BT BI 602 Project Work 12 BT BI 612 Comprehensive Viva Voce 04

Total Credits 16

Total credits…………………………………………………….103

Detailed syllabus is available on our website, http://www.biotech.dauniv.ac.in/syllabus.php

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Summer Training of M.Sc. Students

Our students undergo summer training to various National Institutes like IGIB, New Delhi, NII, New Delhi, Dabur, Ghaziabad, CIMAP, Lucknow, NBRI, Lucknow, CDRI, Lucknow, SGPGI, Lucknow, CCMB, Hyderabad, ICRISAT, Hyderabad, NCCS, Pune, NCL, Pune, NIV, Pune, C-DAC, Pune, NCBS, Bangaluru, TIFR, Mumbai, IISc, Bangaluru etc.

Placement Profile- M.Sc. Biotechnology S.No. Name of the

Student Placement National level

Exam GATE/DBT-

JRF/CSIRUGC/ ICMR/ICAR

Batch

1. Gaurav Agrawal Ph.D. at NCCS, Pune 2017-19 2. Ashish Kumar

Dubey Ph.D. at CSIR IMTECH, Chandigarh

CSIR-NET-JRF, GATE

2017-19

3. Shelar Akshay Uttam

Scientific Assistant, Zydus Pharma, Gujrat

2017-19

4. Gitanjali Swarup CSIR-JRF, DBT(Category-II),

TIFR

2017-19

5. Goyani Shani Kumar

JRF at NII, New Delhi GATE 2017-19

6. Shatakshi Shukla Project JRF, MSU Vadodara CSIR NET-LS, DBT(Category II),

TIFR

2017-19

7. Abhijeet Garg Assistant Professor, Mata Gujri College, Jabalpur

CSIR NET-LS 2016-18

8. Sakshi Singh

Assistant Professor, JNKVV, Jabalpur

CSIR NET-LS 2016-18

9. Suruchi Singhal

Pursuing MBA, IMS DAVV ,Indore

2016-18

10. Shivangi Sharma Ph.D. IIT Jodhpur GATE 2016-18 11. Bodugu Giri BCIL Trainee, Hyderabad 12. Rajarshi Ranjan

Bhattacharjee Preparing for Civil Services GATE 2016-18

13. Kajol Preparing for NET GATE 2016-18 14. Anamika Das IQVIA, Banglore 2016-18 15. Mrudushi Gupta At ICMR 2016-18 16. Ruchita Mehta Microbiologist Lupin,Indore 2016-18

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17. Shaifali Sudhakar Ilishaan Biotech ,Indore 2016-18 18. Ritu Adhikary Project Trainee At Eminent

Biosciences 2015-17

19. Nisha Kanwar Assistant Professor at SAGE University,Indore

DST Inspire fellowship

2015-17

20. Anamika Kumari Ph.D ,IIT , Delhi CSIR NET- JRF 2015-17 21. Love Panchariya Ph.D At ICGEB Delhi GATE, CSIR NET-

JRF, DBTJRF 2015-17

22. Neha Shrivastava

ICMR Gorakhpur, Scientist B 2015-17

23. Manas Ph.D. GATE 2015-17 24. Kaustubh Khaire PhD Scholar at IIT Guwahati GATE 2014-16 25. Saloni Wani PhD Scholar at IISER Bhopal GATE, CSIR NET-

JRF 2014-16

26. Sonal Tiwari CFTRI, Mysore 2014-16 27. Ritika Shrivastava QC at Kilpest India Limited,

Bhopal 2014-16

28. Ritika Kapila PhD Scholar at Delhi University

CSIR NET-JRF

29. Deepika Jaiswal JRF at ICGEB, New Delhi GATE, CSIR NET- JRF, DBTJRF

2017

2014-16

30. Babli Haldar QC at Kilpest India Limited, Bhopal

GATE 2014-16

31. Bhagyashree Dikey

Lecturer at Shri Cloth Market Institute of Professional Studies

2014-16

32. Pooja Thakur Trainee at BCIL (Scigen BioPharma Pvt Ltd), Pune

2014-16

33. Swapnil Hingole PhD Scholar at IISER Bhopal GATE, CSIR NET-JRF, DBT-JRF

2017

2014-16

34. Shalini Tiwari Works at Zocdoc, Bangalore. 2013-15 35. Apurwa Atre Industry: Jr. Associate at

Choksi Laboratories Ltd.

2013-15

36. Akhilesh Tiwari Ph.D. Scholar at Amarkantak University, Amarkantak, Madhya Pradesh

2013-15

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37. Shivam Sharma Industry: Lupin Ltd. 2013-15 38. Aashish Bhatt Ph.D. Scholar at Institute of

Nanoscience and Technology, INST, Mohali.

GATE, CSIR NET-LS

2013-15

39. Renuka Agrawal Ph.D. Scholar at IISER Mohali

GATE, CSIR NET-LS

2013-15

40. Anshul Assaiya

Ph.D. Scholar at National Centre for Cell Sciences (NCCS) Pune

GATE, CSIR NET–JRF, DBTJRF

2013-15

41. Iram Mufti Lecturer at I.P. (P.G.) College, Campus II Bulandshar.

GATE, CSIR NET-LS

2013-15

Placement Profile- M.Sc. Genetic Engineering S.No. Name of the Student Placement Batch

1. Rajat Kumar Ph.D. at Hong Kong Baptist University

2016-18

2. Ismat Naaz Lab Assistant, Ranchi, Jharkhand 2014-16 3. Vishal Kanojiya NISER, Bhubaneswar 2014-16 4. Rajat Joshi Assistant Professor at Shri Dadaji

Education College Barwah, Indore

2014-16

5. Ratnal Belapurkar Ph.D. at Max Planck, Germany 2014-16 6. Anjali Malviya Research Assistant at Shri

Aurobindo Institute of Medical Science, Indore

2014-16

7. Ritu Kumari Quality Analyst, Lupin, Pithampur

2014-16

8. Krutika Gadkari Project Assistant, NCBS Pune 2013-15 9. Sanjay Hammad Ajanta Pharma, Vadodra 2013-15 10. Kirtibala Bhragu Teaching for Civil Services

(MPPSC -mains cleared) 2013-15

11. Dharmendra Yadav

QC, Parenteral Drugs Limited, Indore

2013-15

12. Aniket Mishra Medical Billing & Coder Episource India Pvt. Ltd.

2013-15

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Placement Profile- M.Sc. Bioinformatics S.No. Name of the Student Placement Batch

1. Deepak Bhayal QC at Felix Generics Pvt. Ltd. Pithampur, Indore

2017-19

2. Anuj Mavlankar Ph.D. Scholar at AIIMS Delhi 2016-18

3. Anuranjan Singh Rathore ICMR Jabalpur 2016-18

4. Shikha Bhargava Congnizant,Hyderabad 2016-18

5. Swati Patidar Visiting Faculty at School of

Biotechnology Davv,Indore

2015-17

6. Sujit Das Software Developer, Medha

Innovation, Indore

2015-17

7. Kavita Patidar Spitm Mandleshwar 2015-17

8. Mr. Pavan Sarva BCIL Trainee, Medha Innovation, Indore

2014-16

9. Mr. Mausam Kumravat Software Developer at Merck Sigma- Aldrich Bangalore

2014-16

10. Ms. Bhagyashree Gadodia Bioinformatics Industrial Program Trainee

2014-16

11. Mr. Chandan Kumar Bioinformatics Industrial Program Trainee

2013-15

12. Ms. Saroj Solanki Guest Faculty, Holkar Science

College, Indore

2013-15

13. Mr. Kaloo Mansore MR, Centaur Pharma, Nagpur 2013-15

14. Mr. Kapil Lakhawat Teacher at Bhawani Mandi 2013-15

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Placement Cell:

We have constituted a placement cell and Dr. Hamendra Singh Parmar is the Incharge person. However, most of our students are interested for higher education from various esteemed institutes of India and abroad, instead to go for job. It is noteworthy that our M.Sc. students generally qualify various national and international competitive exams to pursue research or Ph.D. such as NET/ GATE, GRE, TOEFL etc.

Therefore, due to the lack of substantial number of interested students for job companies also did not show any interest inspire approaching them several times.

Research:

Apart from our PhD students, M.Sc. students are also involved in research. As per our course curriculum, M.Sc. II year students have to pursue six-month research project, which is assessed at the end of IV Semester. They cary out this project in School of Biotechnology.

Technologies Developed/ Major Research programs:

Lab scale technology for glucose-1-phosphate (G-1-P) production: A number of

carbohydrate degrading enzymes, viz. Starch phosphorylase, pectinase, pectin methylesterase,

amylase, have been homogeneously purified from plant sources and their physico-chemical

properties have been studied in detail. These enzymes have also been immobilized on suitable

easily available solid supports and bioreactors have been developed which could carry out

the desired process continuously. G-1-P is a cytostatic compound involved in cardiopathy

therapy, as an antibiotic and in circulatory system therapy. Starch phosphorylase (EC

2.4.1.1) is an important enzyme which catalyses the reversible conversion of starch and

inorganic phosphate into G-1-P, and this has been utilized for the production of G-1-P at

lab scale. The enzyme has been immobilized on egg shell and the immobilized enzyme

which is thermostable and reusable has been used in packed bed and fluidized bed reactors and

these can be used in G-1-P production. The waste water from potato chips industry has been

used for the recovery and immobilization of Starch phosphorylase for the production of G-1-P.

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Low methoxyl pectin production:

The enzyme pectin methyl esterase, (PME) (EC 3.1.1.11) acts upon pectin, removing the methyl esterified groups and converting the high methoxyl pectin into low methoxyl pectin and then polygalacturonic acid . This reaction of PME has been exploited for the production of low methoxyl pectin which is used in the preparation of low calorie jellies, jams, marmalades and other confectioneries. Here, PME has been immobilized onto various supports viz. Gelatin, Polyacrylamide and egg shell and these enzymes are found to the more reusable, storage stable and thermostable in characteristic. Using these immobilized enzymes, bioreactors have been developed which could rapidly convert the high methoxyl pectin into low mwthoxyl pectin.

Low molecular weight polygalacturonic acid production: The enzyme endo- polygalacturonase (EC. 3.2.1.15) splits the high molecular weight polygalacturonic acid (PGA) into low molecular weight PGA. The enzyme endo-PGAse has been immobilized over egg shell,

sand and gelatin and has been used to produce low MW PGA. This low MW PGA finds applications in the treatment of ulcers and other diseases.

Development of a technology for fruit juice clarification using immobilized enzymes: A number of industrially important enzymes,viz. Cellulase, xylanase, pectinase, pectin methylesterase have been produced by Solid state fermentation of agricultural wastes using GRAS microorganisms. Presently, this work is in progress and in future, metabolites like gluconic acid, ethanol, lactic acid, citric acid, etc will also be produced using the action of microorganisms on agricultural wastes.

Use of Herbal dyes and colors in painting of idols and textiles: We have lso developed a Herbal Garden in which many important plants and herbs are grown, which are significant for the extraction of herbal dyes. We are developing a Technology for the extraction of herbal dyes from the specific plant parts, rather than using the whole plant. In this respect, we have also organiozed a training programme for the idol makers to use the herbal colors for coloring idols of Gods and Goddesses and toys. This brought awareness among the people to exploit the natural resources, which are cheaper and easy to use than the artificial chemical colors In 2003, we had organized a Workshop for Training the rural people to use herbal dyes for coloring of textiles. These activities have created a lot many opportunities to rural people for obtaining self employment.

Understanding of disease signaling, drug and therapeutic target(s) discoveries

We are also engaged in the basic understanding of the signaling pathways involved in the progression of metabolic disorders. We are also looking for the discoveries and development of potential therapeutic targets. We are also exploring some novel therapeutic targets involved in the regulation of obesity. Almost all of our work is supported by International publications in journals of repute.

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Ph.D. Biotechnology Program

29 students have been awarded Ph.D. in Biotechnology 1. B. Venkaiah (Guide: Dr. Anil Kumar) awarded in July, 1995.

Title of the thesis: Enzymes of Starch Metabolism in Jowar (Sorghum vulgare).

At present - faculty in USA.

2. Sadhana Srivastava (Guide: Dr. Anil Kumar) awarded in January, 1996.

Title of the thesis: Enzymes of Carbohydrate Degradation in Plants.

At present- faculty at the Mata Gujri College, Indore.

3. Anand Nighojkar (Guide: Dr. Anil Kumar) awarded in December, 1996.

Title of the thesis: Pectinase and Petinmethylesterase Enzymes from Germinating Cow Pea (Vigna sinensis)

At present - Principal, Maharaja Ranjit Singh College of Professional Studies, Indore.

4. Sanjay Koul (Guide: Dr. Anil Kumar; Coguide: Dr. G. N. Qazi) awarded in April, 1998.

Title of the thesis: Cloning of Genes coding for Direct Glucose Oxidising Enzymes in Ketogenic Bacteria.

At present in USA

5. Bhartendu Nath Mishra (Guide: Dr. Anil Kumar; Coguide: Dr. S. P. Singh) awarded in July, 1998.

Title of the thesis: Modelling and Experimental Studies of Methane Production in Fixed Bed Bioreactors Treating Industrial Waste Water.

At present- Professor in U P Technical University, Lucknow.

6. Vanita Anand (Guide: Dr. Anil Kumar; Coguide: Dr. V.C. Kalia) awarded in July, 2000.

Title of the thesis: Studies to enhance the Biochemical Process of Hydrogen and Methane Production from Wastes of Plant Origin.

At present- Not known

7. Arun Gupta (Guide: Dr. Anil Kumar; Coguide: Dr. G.N. Qazi) awarded in October, 2000.

Title of the thesis: Transposon Induced Mutations in Gluconobacter oxydans with special reference to its Direct Glucose Oxidation Metabolism.

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At present in USA

8. Vinay Kumar Singh (Guide: Dr. Anil Kumar) awarded in March, 2001.

Title of the thesis: Biocomputing for Designing Universal Primers and In House Kit for-Thalassaemia.

At present in Canada.

9. Savithri Bhat (Guide: Dr. Sushil Kumar; Coguide: Dr. Anil Kumar) awarded in April, 2001.

Title of the thesis: Studies on In vitro Regeneration and Genetic Transformation in Mentha Species.

At present- in an Engineering college, Bangalore.

10. Shipra Agarwal (Guide: Dr. Sushil Kumar; Coguide: Dr. Anil Kumar) awarded in May, 2001.

Title of the thesis: Studies on the In vitro Expression of Secondary Metabolites in Texas wallichiana and Gingko biloba.

At present- in an Industry at Bangalore.

11. Puja Yadav (Guide: Dr. Anil Kumar; Coguide: Dr. V.L.Chopra) awarded in January, 2002.

Title of the thesis: Molecular Cloning and Characterization of Thioesterase in Brassica juncea.

At present- in an industry at Bangalore.

12. Pinaki Prasad Banerjee (Guide: Dr. G.C. Mishra; Coguide: Dr. Anil Kumar) awarded in May, 2002.

Title of the thesis: Studies on a Th2 Specific Co-stimulatory Molecule.

At present in USA.

13. D. Vijaya Raghava Prasad (Guide: Dr. G.C. Mishra; Coguide: Dr. Anil Kumar) awarded in May, 2002.

Title of the thesis: Studies on a Th1 Specific Co-stimulatory Molecule.

At present in USA

14. Sunita Dhawan (Guide: Dr. Anil Kumar, Coguide: Dr. S.P.S. Khanuja) awarded in January, 2003.

Title of the thesis: Somaclonal Polymorphism in Mentha arvensis var. Piperascens holmes:

22

Studies on molecular variation.

At present in CIMAP, Lucknow.

15. Vrajesh Vasant Kumar Parekh (Guide: Dr. G.C. Mishra; Coguide: Dr. Anil Kumar) awarded in April, 2003.

Title of the thesis: Studies on the role of Accessory Molecules in T-Cell Activation.

At present in USA

16. Suchi Srivastava (Guide: Dr. Anil Kumar; Coguide: Dr. Sushil Kumar) awarded in November, 2003.

Title of the thesis: Bioprospecting Potent Plant Compounds Targetted to inhibit Cell Wall Synthesis and DNA Replication in Mycobacterium smeqmatis.

At present in NIPGR, New Delhi

17. Mamta Gupta (Guide: Dr. Anil Kumar) awarded in December, 2003.

Title of the thesis: Study of Cellular Drug Resistance in Philadelphia Chromosome Positive Acute Lymphoblastic Leukaemia.

At present in USA

18. Neelkamal (Guide: Dr. Anil Kumar, Co-guide: P.Usha Sarma) awarded in August, 2006.

Title of the thesis: Evaluation of Aspergillus fumigatus synthetic peptides for their immune response and protective potential. At present in USA

19. Meenal Banerjee (Guide: Dr. R.R. Bhonde, Co-guide: Dr. Anil Kumar) awarded in August, 2006.

Title of the thesis: Studies on cell-cell interaction and / or cell-matrix interaction for modulation of differentiation potential of progenitor cells under controlled condition for tissue engineering applications.

At present in USA.

20. Priti Maheshwari (Guide: Dr. Anil Kumar) awarded in February, 2007.

Title of the thesis: Exploitation of Endangered Plant Species for its Potential Bioactive Natural Compounds using Biotechnological Tools.

At present in Canada.

21. Debargh Kumar S. Dutta (Guide: Dr. G.C. Mishra; Coguide: Dr. Anil Kumar) awarded in May 2008.

Title of the thesis: Role of Dendritic Cells in Naïve CD8+ T-Cells Activation,

23

Proliferation, Differentiation and Generation of Memory.

At present in USA.

22. Raghvendra Mishra (Guide: Dr. Anil Kumar; Coguide: Dr. Sushil Kumar) awarded in Nov 2009.

Title of the thesis: Genetic Mapping of LEAF-LET DEVELOPMENT (LLD) and

MULTIFOLIATE PINNA (MFP) genes in pea (Pisum sativum).

23. Krityanand Kumar Mahatman (Guide: Dr. Anil Kumar) awarded in Dec 2010.

Title of the thesis: Xylanase production using solid state fermentation.

24. Monika Dhote (Guide: Dr. Anil Kumar; Co-guide: Dr. Asha Juwarkar) awarded in April 2013.

Title of the thesis: Studies of Rhizoremediation of polycyclic aromatic hydrocarbon compounds in oil sludge.

25. Meeta Sharma (Guide: Dr. Anil Kumar) awarded in April 2013.

Title of the thesis: Isolation and Characterization of Xylanase from Paenibacillus.

26. Rachana Tiwari (Guide: Dr. Anil Kumar) awarded in June 2013.

Title of the thesis: Immobilization of Starch Phosphorylase: production of glucose -1- phosphate.

27. Ritu Jain (Guide: Dr. Anil Kumar) awarded in May 2015.

Title of the thesis: Purification, characterization and peptide mapping of starch phosphorylase from Spinach leaves.

28. Mukesh Kumar Patidar(Guide: Dr. Anand Nighojkar; Co-guide: Dr. Anil Kumar)

Title of the thesis: Screening of microbes for pectinase: production of pectinmethylesterase and endopolygalacturonase using solid state fermentation.

29. Shivani Bhagwat (Guide: Dr. Anil Kumar)

Title of the thesis: Unraveling the potential of Parthenium hysterophorous as a source of biofuel.

24

Ph. D. students who have presently registered along with title of the thesis

S.No. NAME SUPERVISOR TITLE OF THESIS

1. Mr. Gaurav Singh Dr. Anil Kumar Comparative analysis of some disease

resistat genes: Glycine max L and

Pheaseolus vulgaris. (Thesis Submitted)

2. Ms. Pratibha Maravi Dr. Anil Kumar

Isolation and characterization of cellulase from microbe(s) and optimization of downstream

processing for enzyme production

3. Mr. Rupesh Chawda

Dr. Anand Nighojkar (Supervisor)

Dr. Anil Kumar (Co-supervisor)

Production, purification and characterization of lipase from

microorganism(s) isolated from oil industry waste.

4. Richa Ninava

Dr. Anand Nighojkar (Supervisor)

Dr. Anil Kumar (Co-supervisor)

Endo-1,4- Xylanase: Production, Purification and its application for

Hemicelluloses Bioconversion

5. Fatema Matkawala

Dr. Anand Nighojkar (Supervisor)

Dr. Anil Kumar (Co-supervisor)

Microbial Alkaline Protease: Production, Purification and its

Applications

6. Garima Dukaria

Dr. Anil Kumar

Purification and Characterization of Chitinase from Microbe(s):

Applications in Waste Management

7. Ankita Srivastava

Dr. Anand Nighojkar (Supervisor)

Dr. Anil Kumar(Co-supervisor)

Synthesis, Characterization and Application of Amino Acid mediated

Biofunctionalized Gold Nano-particles

8. Shreya Shah Dr. Anil Kumar Production of Polyhydroxyalkanoates (Bio-plastics) from Agro-Industrial

Waste using Microbe(s)

9. Priyamvada Jha

Dr. Anil Kumar (Supervisor)

Dr. Vinit Kumar (Co-supervisor)

Sucrose Content in Soybean: Genetic Variability in Germplasm and

Identification of Genomic Regions

25

10. Babita Jhariya Dr. Sadhna Nighojkar Isolation, purification,

Characterization and Immobilization of microbial Laccase

11. Vandana Jeswani Dr. Anand Nighojkar

Vermicompost Associated Microflora- Isolation and Study of Application for Bioremediation of Dithiocarbamate and Thiuram Disulphide Fungicides

12. Shashwat Nigam Dr. Mukesh Patidar Production of biodegradable plastic by

utilizing plant material

13. Vinita Yadav Dr. Sadhna Nighojkar Isolation, purification, characterization and immobilization of fungal cellbiose

dehydrogenase

14. Versha Tripathi Dr. Hamendra Singh

Parmar

Study of metabolic modulation based drugs on breast cancer cell lines

15. Aseem Kumar Anshu Dr. Hamendra Singh

Parmar

Identification ofquantitative trait loci (QTLs) assosciated with

phosphatidylcholine content in soyabean

16. Neha Gupta Dr. Anand Nighojkar

Isolation, Identification and application of culturable

microorganisms as biocontrol agent of crop weeds

17. Baishali Roy Dr. Anand Nighojkar

Isolation, Identification and application of potential

microorganisms from wheat rhizosphere to enhance the crop yield

18. Pooja Jaiswal Dr. Hamendra Singh

Parmar

Study of incretin based therapies on breast cancer cell lines

26

19. Vidhi Tiwari Dr. Pramod Kumar

Singh

Therapeutic efficacy of herbal formulations in streptozotocin induced

diabetes mellitus in wistar rats

20. Farida Johar Bandookwala

Dr. Sadhna Nighojkar

Development of bioantifungal approach for prevention of post

harvest losses in tomatoes, strawberries and papaya

We have collaboration signed MOU’s with

INTERNATIONAL COLLABORATION(06):

1. Mangosuthu University of Technology, Durban, South Africa.

2. University of Saskatchewan, Saskatoon, Canada.

3. Institute of Animal Physiology and Genetics, Libechov, Czech Republic.

4. University of Poitiers, France.

5. District Administration, Pingshan New District, China

6. SES, Germany

NATIONAL COLLABORATION (04) :

1. National Research & Development Corporation, New Delhi.

2. Centre for Genomics & Applied Gene Technology, Institute of Integrated Omics

& Applied Biotechnology, Purba, Medinipur.

3. Institute of Life Sciences, Lucknow

4. Indian Institute of Technology, Indore

Dr. Jajoo’s Collaborations/Collaborators

Prof. Suleyman I. Allakhverdiev

Institute of Basic Biological Problems

Puschino, Moscow Region, Moscow;Russia

E mail: suleyman@issp.serpukhov.su

27

Prof. Gyozo Garab

Institute of Plant Biology, Biological Research Center, Hungarian Academy of Sciences,

Szeged, POB 521, H-6701 Hungary

E-mail:gyozo@brc.hu (http://www.szbk.u-szeged.hu/)

Prof. Hong-Gil Nam

The National Scholar of Korea

Professor and Head , Interdisciplinary Bioscience and Bioengineering

Pohang University of Science and Technology

Republic of Korea

E-mail:nam@postech.ac.kr (http://inam.postech.ac.kr/)

Prof. Eva Mari Aro

Plant Molecular Biology Division,

University of Turku, Finland

E-mail:evaaro@utu.fi

Prof. Christine Foyer

Centre for Plant Sciences, Faculty of Biological Sciences,

University of Leeds, UK

www.plants.leeds.ac.uk/people/groups_foy.php

Hazem M. Kalaji PhD, DSc

Associate Professor

Warsaw University of Life Sciences (SGGW),

Warsaw, POLAND

http://agrobiol.sggw.pl/fizjologia/pages/english/personnel/phd-hazem-kalaji.php

Prof Govindjee Govindjee, Professor Emeritus Department of Plant Biology, University of Illinois

265 Morrill Hall, MC-116, 505 South Goodwin Avenue Urbana,IL 61801-3707; USA E-mail:gov@illinois.edu; http://www.life.uiuc.edu/govindjee

28

Prof. Yasusi Yamamoto Graduate School of Natural Science and Technology Okayama University, Okayama 700-8530,Japan

http://www.biol.okayama-u.ac.jp/yamamoto/home.htm

Prof. Asako Kawamori Agape-Kabutoyama Institute of Medicine Nishinomiya;Japan

E mail: kawamori-a@tulip.sannet.ne.jp

Prof. Kunfang Cao, Guangxi University, China

Dr. Parmar’s Collaborations/Collaborators

Dr. Jiri Hatina

Professor Department of Biology, Faculty of Medicine Charles University , Prague, Czech Republic

E-mail: jiri.hatina@lfp.cuni.cz

Dr. Apurba Das

Associate Professor Chemical Sciences, IIT, Indore.

E-mail: apurba.das@iiti.ac.in

29

Research Papers of faculty members:

Year -2019

1. Singh B and Jajoo A (2019) Comparative analysis of fluoride inhibition of photosynthesis in C3 (Wheat) and C4 (Maize) plant. Accepted in Fluoride Journal.

2. Mathur S and Jajoo A (2019) Arbuscular Mycorrhizal fungi protects maize plants from high temperature stress by regulating photosystem II heterogeneity. Industrial crops and products INDCRO 111934

3. Jain L and Jajoo A (2019) Protection of PSI and PSII complexes of wheat from toxic effect of anthracene by Bacillus Subtilis (NCIM 5594). Photosynthesis Research DOI: 10.1007/s11120-019-00692-z

4. Kumar A (2019), Food Preservation: Traditional and Modern Techniques. Acta Scientific Nutrition Health In press.

5. Sunday RM, Obuotor EM and Kumar A (2019), Antioxidant and antidiabetic properties of Mimosa pudica seeds in streptozotocin induced diabetic Wistar rats. Asian J. Biotechnol. In press. DOI:10.3923/ajb.2019.

6. Kumar A (2019), Post-Traumatic Stress Disorder: Symptoms, Screening and Treatment. Current Trends Biotechnol. Microbiol. in press

7. Kumar A (2019), Hepatitis: Types, Mode of Infection, Symptoms and Treatment. LOJ Immun. Infect. Disease 1(2): 34-38 (MS ID: 000110).

8. Kumar A (2019), Some physical, chemical and biological contaminants which are dangerous to food safety. Acta Scientific Nutrition Health 3 (10): 48-50.

9. Matkawala F, Nighojkar S, Kumar A and Nighojkar A (2019), Enhanced production of alkaline protease by Neocosmospora sp. N1 using custard apple seed powder as inducer and its application for stain removal and dehairing. Biocatalysis Agr. Biotechnol. 21: 101310.

10. Matkawala F, Nighojkar A and Kumar A (2019), Antimicrobial peptides in plants: Classes, Databases and Importance, Canadian Journal of Biotechnology. In press.

11. Matkawala F, Kumar A, Nighojkar S and Nighojkar A (2019), A novel thiol-dependent serine protease from Neocosmospora sp. N1, Heliyon, e02246.

12. Sunday R.M., Obuotor E.M. and Kumar, A (2019), Antidiabetic effect of Asparagus adscendens Roxb. in RIN-5F Cells, HepG2 cells, and wistar rats, Canadian Journal of Biotechnology, 3: 132-141.

13. Kumar A (2019), Beneficial Microbiome. Annals Clin. Immunol. Microbiol. 1 (2): 1006

14. Tomar SR and Jajoo A (2019), Photosynthetic performance of two photosystems during the photo-toxicity of fluoranthene, Functional Plant Biology, DOI 10.1071/FP18328.

15. Kumar A (2019), Milk and Milk Products-Good or Bad, Advance Food Science Engineering, In

30

Press.

16. Sunday RM, Obuotor EM and Kumar A (2019), In Vitro Antioxidant Activity of Asparagus adscendes Roxb. Root Extracts, Trends in Applied Sciences Research, In press.

17. Jain L, Dhote M and Jajoo A (2019), Assessment of role of Bacillus subtilis (NCIM 5594) in suppressing toxic effects of anthracene on wheat photosynthesis, Research in Environment and Life Sciences, DOI: 10.33495/aser.

18. Gavel PK, Parmar HS, Tripathi V, Kumar N, Biswas A and Das AK (2019), Investigations of Anti-Inflammatory Activity of a Peptide-Based Hydrogel Using Rat Air Pouch Model, ACS Applied Materials & Interfaces, DOI: 10.1021/acsami.8b19228.

19. Kripnerova M, Parmar HS, Pesta M, Kohoutova M, Kuncova J, Drbal K, Rajtmajerova M and Hatina J (2019), Urothelial Cancer Stem Cell Heterogeneity. Advances in Experimental Medicine and Biology, DOI: 10.1007/978-3-030-14366-4_8.

20. Chordia N, Jain P and Hardia P (2019), Interactome analysis for indentification of common drug target in salmonella species, Journal of Health and Medical Informatics, DOI: 10.4172/2157-7420.1000331.

21. Singh G, Ratnaparkhe M and Kumar A (2019), Comparative analysis of transposable elements from Glycine max, Cajanus cajan and Phaseolus vulgaris, Journal of Experimental Biology and Agricultural Sciences, DOI: http://dx.doi.org/10.18006/2019.7(2).167.177.

22. Singh G and Kumar A (2019), Synteny analysis of Glycine max and Phaseolus vulgaris revealing conserved regions of NBS-LRR coding genes, Bioscience Biotechnology Research Communications (BBRC), DOI: 10.21786/bbrc/12.1/16.

23. Singh G and Kumar A (2019), A Study on Synteny Relationship of Glycine max and Arachis hypogaea using Bioinformatics Approach, Vindhya Bharti, Vol. 1 No. 17, ISSN:- 0976-9986.

24. Chordia N and Kumar A (2019) RNA as a drug target and its tools and databases, Journal of Biotechnology and Biomedicine, DOI: 10.26502/jbb.2642-9128005.

25. Chordia N, Patidar T, and Hardia P (2019) In Silico Identification of Interaction between Ageing and Cardiovascular Disease Genes, Journal of Health & Medical Informatics, DOI: 10.4172/2157-7420.1000329.

26. Singh G (2019), A Review on Various Aspects of Soybean and Soybean Mosaic Virus, Vindhya Bharti, Vol. I, No. 18, ISSN: 0976-9986.

Year -2018

27. Gavel P, Dev D, Parmar HS, Bhasin S and Das AK (2018), Investigation of peptide-based biocompatible injectable shape memory hydrogels: Differential biological effects on bacterial and Human cells, ACS Applied Materials & Interfaces, DOI: 10.1021/acsami.8b00501.

28. Patidar M, Nighojkar S, Kumar A and Nighojkar A (2018), Pectinolytic enzymes-solid state fermentation, assay methods and applications in fruit juice industries-a review. 3 Biotech, 8: 199. DOI: 10.1007/s13205-018-1220-4.

31

29. Hatina J, Parmar HS, Kripnerova M, Hepburn A and Heer R (2018), Urothelial Carcinoma Stem Cells: Current Concepts, Controversies and Methods, Methods of Molecular Biology, DOI: 10.1007/978-1-4939-7234-0_10.

30. Chordia N and Kumar A (2018), Reverse Vaccinology: Use of Genomes for Vaccine Design. Biotechnology Journal, http://dx.doi.org/10.24947/baojpm

31. Bhagwat S and Kumar A (2018), Biolayer Interferometry and its Applications, Journal of Molecular biology techniques, Vol. 2. Issue. 1. 19000106

32. Chordia N and Kumar A (2018), Bioinformatics in Drug Discovery, SciFed Journal of Protein Science, 1, 1-5.

33. Kumar A (2018), Biodiversity and Climate Change, Research & Reviews in BioSciences, ISSN 0974-7532

34. Kumar A (2018), Plant secondary metabolites-Natural antibacterial agents, BAOJ Biotechnology, 4, 029.

35. Nakul S and Kanwar N (2018), A Review on biofilm mediated bioremediation, World Journal of Pharmaceutical Research, 7,458-465.

36. Dhote M, Kumar A, Jajoo A and Juwarkar A (2018), Study of microbial diversity in plant-microbe interaction system with oil sludge contamination, International Journal of Phytoremediation, DOI: 10.1080/15226514.2018.1425668.

37. Singh G and Kumar A (2018), Search for smv resistant gene(s) in soybean, Conference Proceedings Current Research in Pharmaceutical Sciences. DOI: 10.24092/CRPS.2018.0801.C1.003.

Year -2017

38. Parmar HS, Houdek Z, Pešta M, Václava Č, Dvořák P, Hatina J (2017), Protective effect of aspirin against oligomeric Aβ42 induced mitochondrial alterations and neurotoxicity in differentiated EC P19 neuronal cells, Current Alzheimer Research, DOI: 10.2174/1567205014666170203104757.

39. Dhote M, Kumar A, Jajoo A and Juwarkar A (2017), Assessment of hydrocarbon degradation potentials in a plant- microbe interaction system with oil sludge contamination: A sustainable solution, International Journal of Phytoremediation, DOI: 10.1080/15226514.2017.1328388.

40. Kumar A and Chordia N (2017), Bioinformatics Approaches in Food Sciences, Journal of Food: Microbiology, Safety & Hygiene, DOI: 10.4172/2476-2059.1000e104.

41. Kumar A and Chordia N (2017), Role of Microbes in Dairy Industry, Nutrition and Food Science International Journal, DOI: 10.19080/NFSIJ.2017.03.555612.

42. Bhagwat S and Kumar A(2017), Design and Optimization of Enzymatic Saccharification for Bioethanol Production from Parthenium hysterophorus Biomass using Response Surface Methodology, International Journal of Renewable Energy Technology, DOI: 10.1504/IJRET.2017.086817.

43. Kumar A and Chordia N (2017), Role of Microbes in Human Health, Applied Microbiology: Open

32

Access, DOI: 10.4172/2471-9315.1000131.

44. Kumar A and Chordia N(2017), Role of Bioinformatics in Biotechnology, Research & Reviews in BioSciences, ISSN 0974-7532

45. Patidar MK, Nighojkar A, Nighojkar S and Kumar A (2017), Purification and Characterization of Polygalacturonase Produced by Aspergillus niger AN07 in Solid State Fermentation, Canadian Journal of Biotechnology, doi: 10.24870/cjb.2017-000102.

46. Chordia N, Lakhawat K and Kumar A (2017), Identification of Drug Target Properties and its validation on Helicobacter pylori, Canadian Journal of Biotechnology, doi: 10.24870/cjb.2017-000101.

47. Nakul S and Gupta P(2017), Biocolour formation from pigment producing bacteria and its application in textile industry, International Journal of Scientific Research, DOI : 10.15373/22778179

48. Khandia R, Munjal A, Kumar A, Singh G, Karthik K and Dhama D(2017), Cell Penetrating Peptides: Biomedical/Therapeutic Applications with Emphasis as Promising Futuristic Hope for Treating Cancer, International Journal of Pharmacology, DOI: 10.3923/ijp.2017.677.689.

Year -2016

49. Parmar HS, Assaiya A, Agrawal R, Tiwari S, Mufti I, Jain N, Manivannan E, Banerjee T, and Kumar A (2016), Inhibition of Aβ (1-42) oligomerization, fibrillization and acetylcholinesterase activity by some anti-inflammatory drugs: An in vitro study, Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, DOI: 10.2174/1871523015666161229143936.

50. Dhote M, Kumar A and Juwarkar A (2016), Petroleum contaminated oil sludge degradation by defined consortium: Influence of biosurfactant production, The Proceedings of the National Academy of Sciences, India , Section B: Biological Sciences, DOI:10.1007/s40011-016-0778-z.

51. Kumar A (2016), Role of microbes in food and industrial microbiology, Journal of Food & Industrial Microbiology, DOI: 10.4172/2572-4134.1000e101.

52. Bhagwat S, Khaire K, Tiwari S and Kumar A (2016), Comparison of various pretreatments of biomass for increased enzymatic saccharification for the production of biofuel, International Journal of Environmental Science and Technology, DOI: 10.13140/RG.2.2.12072.26880.

53. Patidar M, Nighojkar S, Kumar A and Nighojkar A (2016), Papaya peel valorization for production of acidic pectin methylesterase by Aspergillus tubingensis and its application for fruit juice clarification, Biocatalysis and Agricultural Biotechnology, DOI: 10.1016/j.bcab.2016.02.008.

54. Bhagwat S, Girma AD and Kumar A (2016), Statistical Optimization of Enzymatic Saccharification of Acid Pre-treated Parthenium hysterophorus Biomass using Response Surface Methodology, Biofuels, https://doi.org/10.1080/17597269.2016.1163214.

55. Patidar M, Nighojkar A, Nighojkar S and Kumar A (2016), Purification and characterization of pectin methylesterase produced in solid state fermentation by Aspergillus

33

tubingensis, British Biotechnology Journal, DOI: 10.9734/BBJ/2016/23632.

56. Chordia N, Choudhary S and Kumar A(2016), Identification of Potential Vaccine candidates from Rickettsia species.: A Reverse Vaccinology Approach, BAOJ Biotechnology, Volume 2; Issue 1; 006 .

57. Ratnaparkhe S, Ratnaparkhe MB, Jaiswal AK and Kumar A (2016), Strain Engineering For Improved Bio-fuel Production, Current Metabolomics, DOI:10.2174/2213235X03666150818222343

Year -2015

58. Nalluri JJ, Kamapantula BK, Barh D, Jain N, Bhattacharya A, de Almeida S, Juca Ramos R, Silva A, Azevedo V, and Ghosh P (2015) ,DISMIRA: Prioritization of disease candidates in miRNA-disease associations based on maximum weighted matching inference model and motif-based analysis, BMC Genomics, DOI: 10.1186/1471-2164-16-S5-S12.

59. Barh D, Kamapantula B, Jain N, Nalluri J, Bhattacharya A, Juneja L, Barve N, Tiwari S, Miyoshi A, Azevedo V & Blum K (2015), miRegulome: a knowledge-base of miRNA regulomics and analysis, Scientific reports, DOI: 10.1038/srep12832.

60. Das AK, Maity I, Parmar HS, McDonald TO and Konda M (2015), Lipase-Catalyzed Dissipative Self-Assembly of a Thixotropic Peptide Bolaamphiphile Hydrogel for Human Umbilical Cord Stem-Cell Proliferation, Biomacromolecules, DOI: 10.1021/bm501835v.

61. Nijampurkar B, Qureshi F, Jain N, Banerjee T, Kumar A and Parmar H S (2015), Anti-inflammatory role of thyroid hormones on rat air pouch model of inflammation, Inflammation Allergy Drug Targets, DOI: 10.2174/1871528114666160105113342.

62. Barh D, Kamapantula B, Jain N, Nalluri J, Bhattacharya A, Juneja L, Barve N, Tiwari S, Miyoshi A, Azevedo V, Blum K, Kumar A, Silva A and Ghosh, P (2015), miRegulone: a Knowledge base of miRNA regulomics and analysis, Scientific Reports, DOI: 10.1038/srep12832.

63. Yadav R, Chordia N, Kumar A, and Shobha S (2015), Identification of Targetable Virulence Factor and Drug Screening For Bacterial Pneumonia, IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS), DOI: 10.9790/3008-10212024.

64. Jain R, Jain N, and Kumar A (2015) Structural prediction, glucose-1-phosphate interaction and influence of broad leaves herbicides on spinach leaves α-glucan phosphorylase: An in silico study, Bioengineering and Bioscience, DOI: 10.13189/bb.2015.030401.

65. Bhagwat S, Ratnaparkhe S and Kumar A (2015), Biomass pre-treatment methods and their economic viability for efficient production of biofuel, British Biotechnology Journal, DOI: 10.9734/BBJ/2015/18284.

66. Chordia N, Sharma N and Kumar A (2015), An Interactomic approach for Identification of Putative Drug Targets in Listeria monocytogenes, International Journal of Bioinformatics Research and Applications, DOI: 10.1504/IJBRA.2015.070138.

67. Jain R, Garg S and Kumar A (2015), Starch Phosphorylase: An Overview of Biochemical Characterization, Immobilization and Peptide Mapping, British Biotechnology Journal, DOI:

34

10.9734/BBJ/2015/14522.

68. Jain R and Kumar A (2015), Purification and Characterization of α-Glucan Phosphorylase Isoform Pho 2 from Spinach leaves, British Biotechnology Journal, DOI: 10.9734/BBJ/2015/15106.

Year -2014

69. Maity I, Parmar HS, Rasale DB and Das AK (2014), Self-programmed nanovesicle to Nano fiber transformation of a dipeptide appended bolaamphiphile and its dose dependent cytotoxic behavior, Journal of Materials Chemistry B, DOI: 10.1039/C4TB00365A.

70. Parmar HS, Bhinchar MK, Bhatia M, Chordia N, Raval I, Chouhan DS, Manivannan E, Jatwa R, and Kumar A (2014), Study on gluco-regulatory potential of glimepiride sulphonamide using in silico, in vitro and in vivo approaches, Current Pharmaceutical Design, DOI: 10.2174/13816128206661403 18114832.

71. Tiwari R and Kumar A (2014) Immobilization of starch phosphorylase from germinating wheat seeds, Journal of Pharmacy and Pharmacology, 2, 201-210.

Year -2013

72. Barh D, Jain N, Tiwari S, Field JK, Padin-Iruegas E, Ruibal A, Lopez R, Herranz M, Bhattacharya A, Juneja L, Viero C, Silva A, Miyoshi A, Kumar A, Blum K, Azevedo V, Ghosh P and Liloglou T (2013), A novel in silico reverse-transcriptomics based identification and blood based validation of a panel of sub0type specific biomarkers in lung cancer, BMC Genomics, DOI: 10.1186/1471-2164-14-S6-S5.

73. Nakul S, Solanki S, Meshram M, Songara P and Palkar C (2013), Antibacterial analysis of crude extracts from the leaves and latex of Calotropis procera, Bioscience Biotechnology Research Communications, (BBRC), ISSN: 2321-4007.

74. Sharma M and Kumar A (2013), Xylanase: An Overview, British Biotechnology Journal, 3, 1-28.

75. Sharma M, Mehta S and Kumar A (2013), Purification and characterization of alkaline xylanase secreted from Paenibacillus macquariensis, Advances in Microbiology, DOI: 10.4236/aim.2013.31005

76. Barh D, Barve N, Gupta KK, Chandra S, Jain N, Tiwari S, Sicairos NL, Canizalez-Roman A, dos-Santos AR, Almeida S, Ramos RTJ, de- Abreu AC, Carneiro AR, Soares SC, Castro TLP, Miyoshi A, Silva A, Kumar A, Misra AN, Blum K, Braverman ER and Azevedo V(2013), Exoproteome and secretome derived broad spectrum novel drug and vaccine candidates in Vibrio cholera targeted by Piper betel derived compounds, PLOS ONE, DOI: 1371/journal.pone.0052773.

77. Dhote M, Juwarkar A, and Kumar A (2013), Bioremediation of oil sludge- Present and Future, International Journal of Sustainable Biotechnology, 1, 1-19.

Year -2012

78. Barh D, Gupta KK, Jain N, Khatri G, Sicairos NL, Canizalez-Roman A, Tiwari S, Verma A, Rahangdale S, Hassan SS, dos-Santos AR, Ali A, Guimaraes LC, Ramos RTJ, Devarapalli P,

35

Barve N, Bakhtiar M, Kumavath R, Ghosh P, Miyoshi A, Silva A, Kumar A, 18 Misra AN, Blum K, and Azevedo V (2012) Globally conserved inter-species bacterial PPIs based conserved host-pathogen interactome in C. pseudotuberculosis, C. diphtheria, M. tuberculosis, and Y. pestis: implementation in broad spectrum drug target identification, Integrative Biology, Doi: 10.1039/c2ib20206a.

79. Hassan S, Schneider MP, Ramos RT, Carneiro A, Lima AR , Guimarães LC, Ali A, Bakhtiar S, Pereira U, Santos A, Soares SC, Dorella F, Pinto A, Ribeiro D, Barbosa MS, Almeida S, Abreu VA, Aburjaile F, Fiaux KK, Barbosa EG, Diniz C, Rocha F, Saxena R, Tiwari S, Zambare V, Ghosh P, Pacheco LG, Dowson C, Kumar A, Barh D, Miyoshi A, Azevedo V and Silva A (2012), Whole genome sequence of Corynebacterium pseudotuberculosis strain 162 isolated from camel, Journal of Bacteriology, DOI: 10.1128/JB.01373-12.

80. Barve N, Mandloi P, Kumar A and Jain A (2012) 2D QSAR analysis of inositol derivatives as inositol monophosphatase inhibitors, Advance Research in Pharmaceuticals and Biologicals, ISSN 2250-0774.

81. Tyagi S, Banke J, Chawda R and Kumar A (2012) Suppression of glyphosate toxicity in plants following peroxide treatment, Toxicological & Environmental Chemistry, DOI:10.1080/02772248.2012.701103.

82. Tiwari R and Kumar A (2012), Starch phosphorylase: Biochemical and Biotechnological perspectives, Biotechnology and Molecular Biology reviews, DOI: 10.5897/BMBR12.004.

83. Parmar HS, Jain P, Chauhan DS, Bhinchar MK, Munjal V, Yusuf M, Choube K, Tawani A, Tiwari V, Manivannam E and Kumar A (2012), DPP-IV inhibitory potential of naringin : An in silico, in vitro and in vivo study, Diabetes research clinical practice, DOI: 10.1016/j.diabres.2012.02.011.

84. Sharma M and Kumar A (2012), Optimization of xylanase secretion from Paenibacillus macquariensis, Current Trends in Biotechnology and Pharmacy, ISSN 0973-8916.

85. Hollmann A, Saviello M, Delfederico L, Luerce TD, Barh D, Jain N, Tiwari S, Chandra S, Gupta KK, Zambare V, Kumar A, Christopher L, Misra AN, Kumavath RN, Azevedo V, Semorile L, and Miyoshi A(2012), Tight controlled expression and secretion of Lactobacillus brevis SlpA in Lactobacillus lactis, Biotechnology Letters, DOI: 10.1007/s10529-012-0887-6.

Year -2011

86. Pundhir S and Kumar A (2011), SSPred: A prediction server based on SVM for the identification and classification of proteins involved in bacterial secretion systems, Bioinformation, DOI: 10.6026/97320630006380.

87. Barh D, Jain N, Tiwari S, D’Afonseca V, Li L, Ali A, Santos AR, Guimaraes LC, Soares SDC, Miyoshi A, Bhattacharjee A, Misra AN, Silva A, Kumar A and Azevedo V (2011), A novel comparative genomics analysis for common drug and vaccine targets in Cornebacterium pseudotuberculosis and other CMN group of human pathogens, Chemical Biology & Drug Design, DOI: 10.1111/j.1747-0285.2011.01118.x.

88. Sethi A, Parmar HS and Kumar A (2011), The Effect of Aspirin on Atherogenic Diet-Induced

36

DiabetesMellitus, Basic & Clinical Pharmacology & Toxicology, DOI: 10.1111/j.1742-7843.2010.00663.x

89. Barh D, Tiwari S, Jain N, Ali A, Santos AR, Misra AN, Azevedo V and Kumar A (2011) In silico subtractive genomics for target identification in human bacterial pathogens, Drug Development Research, DOI: 10.1002/ddr.20413.

Year -2010

90. Maheshwari P and Kumar A (2010) RAPD analysis of UB-B induced variation in somaclones of Veronia cinerea, Genes Genomes and Genomics, 4, 58-64.

91. Mahatman KK, Garg N, Chauhan R And Kumar A (2010), Production, purification and characterization of xylanase using alkalo-thermophilic Bacillus halodurans KR-1, Iranica Journal of Energy and Environment, ISSN: 2079-2115.

92. Mahatman KK and Kumar A (2010), Xylanase production using alkalo-thermophilic Bacillus halodurans KR-1 by solid state fermentation, Current Trends in Biotechnology and Pharmacy, ISSN 0973-8916.

93. Barh D, Misra AN, Kumar A and Vasco A (2010), A novel strategy of epitope design in Neisseria gonorrhoeae, Bioinformation, DOI: 10.6026/97320630005077.

94. Barh D, Misra A N and Kumar A (2010) In Silico Identification of dual ability of N. gonorrhoeae ddl for developing drug and vaccine against pathogenic Neisseria and other human pathogens, Journal of Proteomics & Bioinformatics, DOI: 10.4172/jpb.1000125.

95. Dhote M, Juwarkar A, Kumar A, Kanade G S and Chakrabarti T (2010), Biodegradation of chrysene by the bacterial strains isolated from oily sludge, World Journal of Microbiology and Biotechnology, DOI: 10.1007/s11274-009-0180-6.

Year -2009

96. Chaudhary N, Mahajan L, Madan T, Kumar A, Raghav GPS, Katti SB, Haq W and Sarma P U (2009), Prophylactic and therapeutic potential of Asp f1 epitopes in naïve and sensitized BALB/c mice, Immune Network, DOI: 10.4110/in.2009.9.5.179.

97. Barh D, Kumar A and Misra AN (2009), Genomic Target Database (GTD): A database of potential targets in human pathogenic bacteria, Bioinformation, DOI: 10.6026/97320630004050.

98. Barh D, Kumar A, Chatterjee S And Liloglou T (2009), Molecular features, markers, drug targets and prospective therapeutics in cardiac myxoma, Current Cancer Drug Targets, DOI: 10.2174/156800909789271549.

99. Maheshwari P and Kumar A (2009), Antimicrobial activity of Abelmoschus moschatus leaf extracts, Current Trends in Biotechnology and Pharmacy, 3, 260-266, ISSN: 0973-8916.

100. Kumar S, Mishra R K, Kumar A, Srivastava S and Chaudhary S (2009), Regulation of stipule development by COCHLEATA and STIPULE-REDUCED genes in peas Pisum sativum, Planta, DOI: 10.1007/s00425-009-0952-0.

37

101. Barh D and Kumar A (2009), In silico Identification of candidate drug and vaccine targets from various pathways in Neisseria gonorrhoeae, In Silico Biology, DOI: 10.3233/ISB-2009-0399.

102. Mishra RK, Chaudhary S, Kumar A and Kumar S (2009), Effects of MULTIFOLIATE-PINNA, AFILA, TENDRILL-LESS and UNIFOLIATA genes on leafblade architecture in Pisum sativum, Planta, DOI: 10.1007/s00425-009-0931-5.

103. Mishra RK, Kumar A , Chaudhary S and Kumar S, (2009), Mapping of the multifoliate pinna (mfp) leafblade morphology mutation in grain pea (Pisum sativum), Journal of Genetics, DOI: 10.1007/s12041-009-0031-0.

104. Rathore RS, Garg N, Garg S and Kumar A (2009), Starch Phosphorylase: Role in Starch Metabolism and Biotechnological Applications, Critical Reviews in Biotechnology, DOI: 10.1080/ 07388550902926063.

105. Gupta SM, Gupta S and Kumar A (2009), Development of Bed Reactor using Brick Dust immobilized CM-cellulase from seeds of cowpea (Vigna sinensis L). J. Plant Biochem. Biotechnol. 18: 113-116.

106. Garg S, Ali R and Kumar A (2009), Production of Alkaline Xylanase by an Alkalo-thermophilic Bacteria, Bacillus halodurans, MTCC 9512 Isolated from Dung, Current Trends in Biotechnology and Pharmacy, Vol. 3 (1) 90-96, ISSN: 0973-8916.

Year -2008

107. Garg N, Pundhir S, Prakash A & Kumar A (2008), PCR Primer Design: DREB Genes, Journal of Computer Science & Systems Biology, DOI: 10.4172/jcsb.1000002.

108. Maheshwari P, Garg S and Kumar A (2008), Taxoids: Biosynthesis and in vitro production, Biotechnology Molecular Biology Reviews, DOI: 10.5897/BMBR.

109. Garg N, Pundhir S, Prakash A and Kumar A (2008), Primer designing for DREB1A, A cold induced gene, Journal of Proteomics & Bioinformatics, DOI: 10.4172/jpb.1000006.

110. Pundhir S, Vijayvargiya H and Kumar A (2008), PredictBias: a server for the identification of genomic and pathogenicity islands in prokaryotes, In Silico Biology, ISSN: 1386-6338.

111. Garg N, and Kumar A (2008), Immobilization of starch phosphorylase from cabbage leaves: Production of glucose-1-phosphate, Brazilian Journal of Chemical Engineering, DOI: 10.1590/S0104-66322008000200002.

Year -2007

112. Garg S and Kumar A (2007), Immobilization of starch phosphorylase from seeds of Indian millet (Pennisetum typhoides) variety KB 560, AFRICAN JOURNAL OF BIOTECHNOLOGY, DOI: 10.5897/AJB2007.000-2434.

113. Maheshwari P, Garg S, Sood PP and Kumar A (2007), Xylanase: A biotechnological perspective, VAK , 2, 44-56.

114. Maheshwari P, Songara P, Kumar S, Jain P, Srivastava K and Kumar A (2007), Alkaloid production

38

in Vernonia cinerea: Callus, cell suspension and root cultures, Biotechnology Journal, DOI: 10.1002/biot.200700033

115. Garg S, Sohani N, Pundhir S and Kumar A (2007), Primer designing for Endo-1, 4--

Xylanase gene, Journal of Cell and Tissue Research, Vol. 7 (2) 1147-1154, ISSN: 0973- 0028.

Year -2006

116. Maheshwari P and Kumar A (2006), Organogenesis, shoot regeneration and flowering response of Vernonia cinerea to different auxin / cytokinin combinations. In Vitro Cellular & Developmental Biology, Plant, DOI: 10.1079/IVP2006825.

117. Garg N and Kumar A (2006), Primer designing of DREB2A, a drought resistant gene in Glycine max, Journal of Cell and Tissue Research, DOI: 10.4172/jcsb.1000002

118. Nighojkar S, Phanse Y, Sinha D, Nighojkar A and Kumar A (2006), Production of polygalacturonase by immobilized cells of Aspergillus niger using orange peel as inducer, Process Biochemistry, DOI: 10.1016/j.procbio.2005.12.009.

119. Maheshwari P and Kumar A (2006), In vitro high frequency of shoot regeneration in Abelmoschus moschatus, Journal of Cell and Tissue Research, 6, 627-632.

Year -2005

120. Kamal N, Chowdhury S, Madan T, Sharma D, Attreyi M, Haq W, Katti SB,Kumar A and Sarma U P (2005), Tryptophan residue is essential for immunoreactivity of a diagnostically relevant peptide epitope of A. fumigates, Molecular and Cellular Biochemistry, DOI: 10.1007/s11010-005-2056-x.

121. Banerjee M, Kumar A and Bhonde RR (2005), Reversal of Experimental Diabetes by multiple bone Transplantation, Biochemical and Biophysical Research Communications, DOI: 10.1016/j.bbrc.2004.12.176.

Year -2004

122. Khan I, Desai DV and Kumar A (2004), Carbochips- a new energy for old biobuilder, Journal of Bioscience and Bioengineering, DOI: 10.1016/S1389-1723(04)00291-9.

Year -2003

123. Parekh VV, Prasad DVR, Banerjee PP, Joshi BN, Kumar A and Mishra GC (2003), B-cells activated by lipopolysaccharide, but not by anti-Ig and anti-CD40 antibody, induce anergy in CD8+ T cells: Role of TGF-1, The Journal Of Immunology, DOI: 10.4049/jimmunol.170.12.5897.

Year -2002

124. Gupta M, Kumar A and Dabadghao S (2002), In vitro resistance of leukaemic blasts to prednisolone in bcr-abl positive childhood acute lymphoblastic leukaemia, The Indian journal of medical research, ISSN: 0971-5916.

125. Banerjee PP, Dass S V, Mathew A, Parekh VV, Prasad DVR, Joshi B, Kumar A and Mishra GC (2002), Evidence for GP96, a stress protein, functions as Th2 specific costimulatory molecule, The

39

Journal Of Immunology, DOI: 10.4049/jimmunol.169.7.3507.

126. Gupta M, Kumar A and Dabadghao S (2002), Resistance of bcr-abl positive acute lymphoblastic leukaemia to daunorubicin is not mediated by mdr 1 gene expression . American journal of hematology, DOI: 10.1002/ajh.10212.

127. Prasad DVR, Parekh VV, Joshi BN, Banerjee PP, Parab P, Chattopadhyay S, Kumar A and Mishra GC (2002), The Th1-specific costimulatory molecule, M150, is a posttranslational isoform of LAMP-1. The Journal Of Immunology, DOI: 10.4049/jimmunol.169.4.1801.

128. Bhat S, Maheshwari P, Kumar S and Kumar A (2002), Mentha species: In vitro Regeneration and Genetic Transformation. Molecular Biology Today, ISSN: 1468-5698.

Year -2001

129. Samanta J and Kumar A (2001), TAXON: A Software for Management of Plant Database using Visual Basic, Biotechnology Software and Internet Report, DOI: 10.1089/152791601753304411.

130. Bhat S, Gupta SK, Tuli R, Khanuja SPS, Sharma S, Bagchi GD, Kumar A, and Kumar S (2001), Photoregulation of adventitious and axillary shoot proliferation in menthol mint, Mentha arvensis, Current Science, ISSN: 0011-3891.

131. SinghV K and Kumar A (2001), PCR Primer Design, Molecular Biology Today, 2(2): 27-32.

132. Singh VK, Mangalam AK, Kumar A, and Naik S, (2001), Universal primers can amplify tumor necrosis factor gene across species, Molecular Biology Today. 2, 11-12.

133. Gupta A, Singh V K, Qazi G N and Kumar A (2001), Gluconobacter oxydans: A Biotechnological perspective, Journal of molecular microbiology and biotechnology, ISSN: 1464-1801.

Year -2000

134. Agrawal S, Kumar A, Banerjee S, Gupta MM, Verma RK, Singh DV and Kumar S (2000),Production of bilobalide in cultures of clone GBC-1 of Ginkgo biloba, Journal of Medicinal and Aromatic Plant Science, 22 (4A) – 23 (1A): 194 – 196.

135. Singh VK and Kumar A (2000), OLREA: A faster restriction enzyme analysis using JAVA, Biotechnology software and Internet Report, DOI: 10.1089/152791600459920.

136. Singh VK and Kumar A (2000), PCR Recipe: Software for setting up PCR reactions, Biotechnology software and Internet Report, DOI: 10.1089/152791600459911.

137. Felder M, Gupta A, Verma V, Kumar A, Qazi GN and Cullum J(2000), The pyrroloquinoline quinone synthesis genes of Gluconobacter oxydans, FEMS Microbiology Letters, DOI: 10.1111/j.1574-6968.2000.tb09429.x.

138. SinghVK, Govindrajan R, Naik S and Kumar A (2000) The effect of hairpin structure on

PCR amplification efficiency, Molecular Biology Today, 1(3): 67-69.

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Year -1998

139. Singh VK and Kumar A (1998), Production and purificationof extracellular cellulase from Bacillus brevis VS-1, Biochemistry and molecular biology international, 45(3):443-52.

140. Mishra BN and Kumar A, (1998), Operational Characteristics of anaerobic fixed bed reactors: waste water treatment and methane production, The Journal for Nature Conservation, 10, 37-45.

141. Mishra BN, Singh S P and Kumar A ,(1998), Start-up and operational behaviour of an anaerobic fixed bed bioreactor treating pharmaceutical wastewater, Crop Research, 16 , 395-401.

Year -1997

142. Nighojkar A, Srivastava S & Kumar A ,(1997) ,Pectin Carbohydrates and their commercial uses, The Journal for Nature Conservation, 9, 141-151.

143. Kumar A & Mishra BN (1997), Primer Premier 4 ,Biotechnology Software&Internet Journal, 31-33, Review

144. Koul S, Verma V, Kumar A and Qazi GN (1997), Efficient Recovery of Plasmid DNA from Erwinia herbicola with High Nuclease Activity, Biotechniques, DOI: 10.2144/97234bm08.

145. Koul S, Verma V, Kumar A and Qazi GN (1997), Plasmid profile of Erwinia herbicola ATCC 21998, Current Science. 72, 876-879.

146. Mishra BN, Singh SP & Kumar A (1997), A biofilm model for fixed bed anaerobic reactors: Performance analysis considering diffusional resistances and axial dispersion, The Genetic Engineer and Biotechnologist, 17, 5-21.

147. Mishra BN and Kumar A (1997), Anaerobic treatment of potato-starch wastewater using a Foam bed bioreactor, The Genetic Engineer & Biotechnologist, 17, 165-173.

148. Nighojkar SA & Kumar A (1997), Starch Phosphorylase: Biochemical, Molecular and Biotechnological aspects, The Genetic Engineer & Biotechnologist, 17, 189-202.

149. Kalia VC, Anand V, Kumar A, and Joshi A P (1997), Effiecient biomethanation of plant materials by immobilized bacteria, R'97 Recovery, Recycling, Reintegration Congress Proceedings, Vol.1, 200-205.

Year -1996

150. Venkaiah B & Kumar A (1996), Multiple forms of Starch phosphorylase from Sorghum leaves, Phytochemistry, DOI: 10.1016/0031-9422(95)00709-1.

151. Srivastava S, Nighojkar A & Kumar A (1996), Immobilization of Cuscuta reflexa Starch phosphorylase : Production of glucose-1-phosphate using bioreactors, Journal of Fermentation and Bioengineering, DOI: 10.1016/0922-338X(96)80591-5.

152. Nighojkar A, Srivastava S & Kumar A (1996), Immobilization of endo-polygalacturonase from germinating Vigna sinensis seeds, Indian journal of experimental biology, 34, 1248-1253.

153. Nighojkar A, Srivastava S & Kumar A (1996), Endo-Polygalacturonase from germinating Vigna

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sinensis Seeds, Plant Physiology and Biochemistry, 23, 14-20.

154. Srivastava S, Nighojkar A & Kumar A (1996), Demethoxylation of Pectin using immobilized Cuscuta reflexa pectin methylesterase, The Genetic Engineer and Biotechnologist, 16, 73-80.

155. Upadhye SP & Kumar A (1996), Immobilization of starch phosphorylase from Bengal gram seeds: Production of Glucose-1-phosphate, The Genetic Engineer and Biotechnologist, 16, 145-151.

Year -1995

156. Venkaiah B & Kumar A (1995), A process for the recovery and immobilization of starch phosphorylase from Starch-based Industrial wastewater, Biotechnology and Applied Biochemistry, 21,77-85, ISSN: 1470-8744.

157. Upadhye S & Kumar A (1995), Purification of starch phosphorylase from germinating Bengal gram (Cicer arietinum L.) seeds, Crop Research Journal, 10, 360-367.

158. Srivastava S, Nighojkar A & Kumar A (1995), Purification and characterization of Starch phosphorylase from Cuscuta reflexa filaments, Phytochemistry, 39, 1001-1005.

159. Nighojkar A Srivastava S & Kumar A (1995), Production of Low Methoxyl Pectin Using Immobilized Pectinesterase Bioreactors, Journal of Fermentation and Bioengineering, DOI: 10.1016/0922-338X(95)94202-3.

Year -1994

160. Srivastava S, Nighojkar A & Kumar A (1994), Multiple forms of Pectin methylesterase from cuscuta reflexa filaments, Phytochemistry, DOI: 10.1016/S0031-9422(00)90390-X.

161. Venkaiah B & Kumar A (1994), Egg shell bound starch phosphorylase packed bed reactor for the continuous production of glucose 1 phosphate, Journal of Biotechnology, DOI: 10.1016/0168-1656(94)90017-5.

162. Nighojkar A, Srivastava S & Kumar A (1994), Pectinmethylesterase from germinating Vigna sinensis seeds, Plant Science, DOI: 10.1016/0168-9452(94)90198-8.

Year -1991

163. Kumar A (1991), Biosynthesis of bacterial glycogen and its regulation, Current Science, 60, 478-485, Review article.

164. Venkaiah B & Kumar A (1991) Predicted secondary structure of glycogen phosphorylase from Escherichia coli as deduced using Chou-fasman model, Indian journal of pathology & microbiology, 34, 270-275, ISSN: 0377-4929

165. Venkaiah B, Srivastava S & Kumar A (1991) Dissociation of purified Starch phosphorylase from young banana (Musa paradisiaca) leaves, Indian journal of Plant Physiology, 34, 97-101.

166. Venkaiah B, Srivastava S & Kumar A (1991), Starch phosphorylase from banana (Musa paradisiaca) leaves, Plant physiology and Biochemistry, 18, 54-56.

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Papers/Poster accepted for Presentation at Conferences

Papers/Poster accepted for Presentation at Conferences 1. Kumar A. & Sanwal, G.G. (1978) some physical properties of starch phosphorylase from

mature banana (Musa paradisiaca) leaves. Proc. Soc. Biol. Chemists India, p.84, Oct., 1978 Delhi. Also published in Indian J. Biochem. Biophys. (1979) 16, S84.

2. Kumar,A. & Sanwal, G.G. (1979) Purification and properties of alpha glucan phosphorylase from tapioca Leaves. Proc. Indian Sci. Conger. Assoc, Section of Chemistry part IV p. 19, Jan. 1979, Hyderabad.

3. Kumar, A. & Sanwal, G.G. (1979) some immunological studies on starch phosphorylase from banana Leaves. Proc. Soc. Biol. Chemists India, p. 76, Oct. 1979, Lucknow. Also published in Indian J. Biochem. Biophys. 17, S91-92.

4. Kumar A. (1980) Intracellular localization of starch phosphorylase from Musa paradisiaca leaves. Proc. Indian Soi. Congr. Asso. Section of Botany part III, P. 79, Jan., 1980, Calcutta.

5. Kumar A. & Sanwal, G.G. (1981) Kinetics of Starch phosphorylase from mature banana (Musa paradisiaca) leaves. Proc. Soc. Biol. Chemists India Nov., 1981 Baroda.

6. Kumar A. (1982) Kinetics of starch phosphorylase from young banana (Musa paradisiaca) leaves. Proc. Indian Sci. Congr. Asso. Section of Chemistry Part III p. 138, January 1982, Mysore.

7. Kumar A. (1982) Subcellular localization of multiple forms of starch phosphorylase in different plant Leaves during development. Proc. Indian. Sci. Congr. Asso. Section of Botany part III p. 161-162, Jan., 1982, Mysore.

8. Kumar A & Sanwal, G.G. (1982) Biophysical Characterization of starch phosphorylase Proc. of All IndiaSymposium of Biophys. Oct., 1982, Lucknow.

9. Kumar A. & Sanwal, G.G. (1982) Inhibition studies on starch phosphorylase isolated from young banana Leaves. Proc. Soc. Biol. Chemists India p.180-181, Nov.,1982.

10. Chatterjee, U. & Kumar A. (1982) Immobilized catalase from goat liver. Proc. Soc. Biol Chemists India p. 183, Nov., 1982, Chandigarh.

11. Kumar A. (1983) Studies on the inhibition of starch phosphorylase isolated from mature banana (Musa paradisiaca) leaves Proc. Indian Sci. Congr. Asso. Section of Chemistry, Part III p. 105, Jan., 1983, Tirupati.

12. Kumar A. & Sanwal, G.G. (1983) purification and physicochemical properties of starch phosphorylase From young banana leaves. Proc. Indian Sci. Congr. Asso. Section of

43

Chemistry Part IV Jan., 1983, Tirupati.

13. Chatterjee U., Kumar, A. & Sanwal,G.G. (1983) Purification and partial characterization of goat liver Catalase. Proc. Soc. Biol. Chemists India p. 134, Nov., 1983, Pune.

14. Kumar A. & Sanwal, G.G. (1984) Starch Phosphorylase from topioca (Manihot utilissima) tuber : Isolation and some physico-chemical properties. Proc. Indian Sci. Congr. Asso. Section of Chemistry, Part III p. 75. Jan., 1984, Ranchi.

15. Kumar A (1984) Partial purification and characterization of Starch phosphorylase from cabbage (Elephantopus Scaber) leaves. Proc. Indian Soi. Congr. Asso. Section of Botany, Part III p.68, Jan., 22 1984, Ranchi.

16. Kumar, A. & Sanwal, G.G. (1985) Dissociation constants and thermodynamic data of starch Phosphorylase from banana leaves using horizontal polyacrylamide slab gel electrophoresis. Proc. Indian Sci. Congr. Asso. Section of Chemistry Part III p. 43, Jan. 1985, Lucknow.

17. Kumar A. & Preiss J. (1986) Nucleotide sequence determination of glg A from Escherichia coli, the Structural gene of glycogen synthase. Fed. Proc. 45, 1978.

18. Lea, Y.M., Kumar, A, Thelan, A.P. & Preiss J. (1986) Characterization of an E. coli ADPglucose Synthetase allosteric mutant enzyme. Sixth International Conference on Methods in Protein Sequence Analysis. Abs. D-70, Aug. 1986, Seattle, washington.

19. Kumar A., Romeo, T. & Preiss, J. (1987) Biosynthesis of bacterial glycogen : Sequence of an open reading Frame separating Escherichia coli glg B and glg C and in vitro exprssion of glycogen genes. Fed, Proc. 46, 1935.

20. Lee, Y.M., Kumar A., Tanaka, T. & Preiss J. (1987) An E. coli ADPglucose synthetase allosteric mutant Enzyme: DNA sequencing of the structural gene and site directed mutagenesis. Fed. Proc. 46,2045.

21. Kumar, A., Tanaka, T. Lee, Y.M. & Preiss, J. (1988) Biosynthesis of bacterial glycogen : Use of site Directed mutagenesis to probe the role of Tyrosine 114 in the catalytic mechanism of ADPglucose synthetase from Escherichia coli FASEB journal 2 (15) Abst. 6022, p. A1332.

22. Ghosh, P., Kumar A., Tanaka,T., Lee, Y.M. & Preiss, J. (1988) Altered allosteric properties of mutant E. Coli K-12 strain 618 is due to changes of Lys 296 and Gly 336. FASEB journal 3, Abst.

23. Kumar A. (1990) Secondary structure of glycogen phosphorylase from Escherichia coli. Proc. Indian Sci. Congr. Assoc. Section of Chemistry, Part III, p. 192, Feb., 1990, Cochin.

24. Kumar A. (1991) Predicted secondary structure of maltodextrin phosphorylase from Escherichia coli. Proc. Indian Sci. Congr. Assoc., Section of Biochemistry, p.19 Jan., 3-6,

44

1991, Indore.

25. Venkaiah, B. & Kumar, A (1992) Dissociation of purified starch phosphorylase from young banana (Musa paradisiaca) leaves. 79th Indian Science Congress held at Baroda.

26. Venkaiah, B. & Kumar A. (1993) Predicted secondary structure of a putative protein encoded by gene present synthetase enzyme in genome of Escherichia coli. 80th Indian Science Congress held at Goa, Jan. 3-7, 1993.

27. Venkaiah B., Sani, R.K., & Kumar A. (1994) Production of glucose-1-phosphate by immobilized cereal starch phosphorylase. XVI All India Cell Biology Conference & Symposia, Indore, Jan. 7-9, 1994.

28. Srivastava S., Nighojkar A. & Kumar, A. (1994) Pectinmethylesterase from Cuscuta reflexa filaments, XVI All India Cell Biology Conference & Symposia, Indore Jan. 7-9, 1994.

29. Venkaiah, B., Sani, R.K. & Kumar A. (1994) Egg shell bound enzyme packed bed reactor for the production of matose and glucose-1-p XVI IUBMB meeting held at New Delhi Sept. 19-22, 1994 Vol II., p.148.

30. Nighojkar, A., Srivastava, S. & Kumar A. (1994) Pectinmethylesterase from germinating Vigna sinensis seeds. XVI IUBMB meeting held at New Delhi Sept. 19-22, 1994. Vol. II., p.252.

31. Srivastava S., Nighojkar A., & Kumar A. (1994) Pectinmethylesterase from Cuscuta reflexa (dodder), XVI IUBMB meeting held at New Delhi, Sept. 19-22, 1994, Vol. II, p.272.

32. Kumar A. (1996) Immobilization of Pectin methylestarase isolated form Vigna Sinensis seeds International workshop Bioencapsulation V Postdam, Germany, Sept. 24-26, 1996.

33. Upadhye, S., & Kumar A. (1996), Production of glucose-1-phosphate by bioreactor using immobilized Starch phosphorylase from bengal gram seeds. National sympsia on Modern Perspectives in Biochemistry and Biothechnology and Recent Developments in Green Vegetation and other Photosynthetic organisms Research. Oct 25-27 1996 Lucknow.

34. Upadhye, S., Singh, V. K., and Kumar, A. (1996) Partial purification and characterization of cellulose from cow pea (Vigna sinensis) seeds. 65th Annual meeting Soc. Biol. Chem. India, Nov. 20-23, 1996, Bangalore.

35. Kumar, A. & Srivastava, S. (1996) Demethoxylation of Pectin using immobilized Cuscuta reflexa pactin methylesterase 65th Annual meeting Soc. Biol. Chem. India, Nov. 20-23, 1996, Bangalore.

36. Kumar A. (1997) Demethoxylation of pectin using immobilized Cusucta reflexa pectin methylesterase Bioencapsulation VI Conference Aug. 30-Sept.1, 1997.

45

37. Kumar A. (1997) Production of glucose-1-phosphate using bioreactors Bioencapsulation VI conference Aug. 30-Sept.1,1997, Spain.

38. Mishra, B.N. & Kumar A. (1997) A mathematical model of biofilm for the production of biogas in a fixed bed bioreactor. National Symposium on Community and Institutional Biogas Complexes, Punjab Agricultural University, Ludhiana, June 19-20, 1997.

39. Mishra, B.N. & Kumar A. (1997) Mathematical modelling and simulation study of an anaerobic fixed film Bioreactors. 38th annual meeting, Association of Microbiologists of India and Conference on Microbes in Sustainable Development. Jamia Millia Islamia Campus, New Delhi, Dec. 12-14-1997.

40. Mishra B.N. & Kumar A. (1998) Start up and operational behavior of a fixed anaerobic bed bioreactor Treating pharmaceutical wastewater. 85th Indian Science Congress, Osmania University, Hyderabad, Jan. 3- 7, 1998.

41. Bhat S., Tewari V., Khanuja, S.P.S., Kumar A. and Kumar S. (1999) An Agrobacterium tumefaciens mediated transient gene expression system in the essential oil crop Mentha arvensis National symposiumon Plant Physology and Biochemistry, Devi Ahilya University, Indore, Feb. 15-17, 1999.

42. Agarwal, S., Banerjee, S., Kumar, A., and Kumar, S. (2000) Somatic embryogenesis in cell cultures of the Himalayan yew Taxus wallichiana. National Seminar on the Frontiers of Research and Development in Medicinal Plants. September 16-18, 2000, Lucknow

43. Kumar, A. (2000) Plant and Microbial Cellulases. National conference on Plant Biotechnology, Biodiversity & Ecorestoration for Gobal prosperity. Nov. 24-26, 2000.

44. Menaria, K., Dubey, S., and Kumar, A (2000) Production of xylanase from thermo-alkanophillic microbe. 69th Annual meeting of Society of Biological Chemists (India), Calcutta. Dec. 7-9, 2000

45. Mathur, P., Menaria, K., and Kumar, A (2000) Mutational studies for maximised production of xylanase from thermophillic microbe. 69th Annual meeting of Society of Biological Chemists (India), Calcutta. Dec. 7-9, 2000

46. Maheshwari, P. and Kumar, A. (2001) Xylanase from germinating Vigna sinensis seeds. 70th Annual meeting of Society of Biological Chemists (India), Hyderabad , Dec. 27-29, 2001.

47. Thomas, S.C., Dharkar, P., Dharkar, N. and Kumar, A. (2001) A Novel program for predicting plant gene sequences and its comparison with existing web based programs. 70th Annual meeting of Society of Biological Chemists (India), Hyderabad , Dec. 27-29, 2001.

48. Thomas, S.C., Dharkar, P., Dharkar, N. and Kumar, A. (2001) Application of base composition statistics to develop algorithm for gene identification in genomic sequences of

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rice and other monocots. 70th Annual meeting of Society of Biological Chemists (India), Hyderabad , Dec. 27-29, 2001.

49. Kumar, A., Dhawan, S., and Khanuja, S. (2003) RAPD Analysis for somaclonal polymorphism in regenerated plantlets of Mentha arvensis. XIX International Congress of Genetics, Melbourne, Australia, July 6-11, 2003.

50. Neel Kamal, Chowdhury, S., Madan, T., Haq, W., Katti, S. B., Kumar, A. and Usha Sarma, P. (2004) Tryptophan residue is essential for immuno-reactivity of a diagnostically relevant peptide epitope of A. fumigatus. 7th Federation Meeting of Immunological Societies of Asia-Oceania (FIMSA), Adelaide, Australia, December 12-16, 2004.

51. Kumar, A. (2005) Enzymes of carbohydrate metabolism and their exploitation in biotechnology. 4th World Congress of Cellular & Molecular Biology. Poitiers, France, October 7-12, 2005.

52. Garg, N. and Kumar, A. (2006) Primer Designing of DREB2A, a drought resistant gene in soybean. 93rd Indian Science Congress Association meeting, Hyderabad, January 3 to 7, 2006.

53. Garg, N. and Kumar, A. (2006) Immobilization of starch phosphorylase and production of glucose-1-phosphate. 3rd International Symposium on Signals, sensing and plant primary metabolites. Potsdam, Germany, April 26-29, 2006.

54. Maheshwari, P. and Kumar, A. (2006) Accumulation of anthocyanin pigments in rapidly dividing callus and suspension cultures of Vernonia ceranea. 11th International Congress on Plant Tissue Culture, Beijing, China, August 13-18, 2006.

55. Pundhir, S., Vijayawargiya, H. and Kumar, A. (2006) PredictBias: Detection of pathogenic islands in pathogenic bacteria. International Conference of Bioinformatics, Delhi, India, December 18-20, 2006.

56. Garg, S., Sohani, N., Pundhir, S. and Kumar, A. (2006) Primer designing of endo-1,4--xylanase gene. National Conference on Biotechnology, Science & Environment. Indore, India, Dec. 28-29, 2006.

57. Maheshwari, P. and Kumar, A. (2006) Plant tissue culture technology for medicinal plant propagation and production of secondary metabolites. National Conference on Biotechnology, Science & Environment. Indore, India, Dec. 28-29, 2006.

58. Pundhir, S. and Kumar, A. (2006) In Silico Classification of bacterial virulence factors. National Conference on Biotechnology, Science & Environment. Indore, India, Dec. 28-29, 2006. Sachin Pundhir won Prof. Vimal Sharma Young Scientist Award on this paper. Award included a Gold 25 Medal and a Certificate to him).

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59. Dayma, Y., Singh, A. and Kumar, A. (2006) ‘Development of a novel approach to find out the virulence factor in Mycobacterium tuberculosis CDC 1551 and Mycobacterium avium’. International Symposium on New Frontiers in Tuberculosis Research, Dec. 4 to 6, 2006, New Delhi, India.

60. Pundhir, S., Vijayawargiya, H. and Kumar, A. (2008) PredictBias: a server for the identification of genomic and pathogenicity islands in prokaryotes. International Conference on Bioinformatics (InCoB2008), October 20-23, 2008 , Taipei, Taiwan.

61. Pundhir, S. and Kumar, A. (2008) SSPred: a prediction server based on SVM for the identification and classification of proteins involved in bacterial secretion systems. International Conference on Bioinformatics (InCoB2008), October 20-23, 2008 , Taipei, Taiwan.

62. Mahatman, K. K., Chauhan, R. and Kumar, A. (2009) Production, purification and characterization of xylanase from an alkalo-thermophilic bacteria, Bacillus halodurans strain KR- 1. 5th World Congress of Cellular and Molecular Biology November 02 to 06,2009,Indore,India.

63. Yadav, K., Pundhir, S., Singh, T.R. and Kumar, A. (2009) GGRP: GenBank Genome Record Parser. 5th World Congress of Cellular and Molecular Biology November 02 to 06, 2009, Indore, India.

64. Patidar, M., Nighojkar, A. and Kumar, A. (2012) Screening and isolation of pectin degrading microorganisms from decaying fruits. International Conference of Association of Microbiologists, India. November 21-24, 2012. KIIT University, Bhubneshwar, India.

65. Kumar, A. and Dhote, M. (2013) Microbial assisted bioremediation technology for management of oil sludge. Ist International Conference of Emerging Industry (ICEI-2013) November 6-7, 2013, Shenzhen, China.

66. Patidar, M., Nighojkar, A. and Kumar, A. (2013) Fungal endopolygalacturonase production using solid state fermentation. International Conference of Association of Microbiologists, India. November 17-20, 2013 M D University, Rohtak, India.

67. Maravi P. and Kumar A. (2017) “Screening of Cellulase Producing Bacteria from the Agriculture Waste”. Microbes for Sustainable Develoment: Scope & Applications, November 16-19, 2017, Babasaheb Bhimrao Ambedkar University, Lucknow, India.

68. Shrivastava A., Nighojkar A., Kumar A. (2018) “Synthesis and Characterization of amino acid mediated Iron Nanoparticles” National conference of "Women Empowerment Education, Environment Biodiversity, Health and Agriculture", March 23-24, 2018, Dr Saroj Asthana Memorial Cancer Foundation, Society for Health Education Family Welfare (SHEFWEL), Bhopal.

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69. Singh G. and Kumar A. (2018) “Application of Plant Biotechnology in Improving Natural and Nutritional Product in Soybean,” National conference of "Women Empowerment Education, Environment Biodiversity, Health and Agriculture", March 23-24, 2018, Dr Saroj Asthana Memorial Cancer Foundation, Society for Health Education Family Welfare (SHEFWEL), Bhopal.

70. Dukariya G. and Kumar A. (2018) “Screening and Isolation of chitinase producing microbes from soil enriched in chitinous waste” National conference of "Women Empowerment Education, Environment Biodiversity, Health and Agriculture", March 23-24, 2018 Dr Saroj Asthana Memorial Cancer Foundation, Society for Health Education Family Welfare (SHEFWEL), Bhopal.

No. of Books Published: Twelve (13) + 29 chapters in edited books 1. Sanwal, G.G. & Kumar, A. (1988) Regulation of starch biosynthesis in leaves of higher plants

in Advances in Frontier Areas of Plant Biochemistry (Singh, R. & Sawhney, S.K. eds.) p. 147-167, Prentice Hall of India Pvt. Ltd. New Delhi.

2. Hand book of Enzymes (2001) by Dr. Anil Kumar, Agrotech Publishing Academy, Udaipur. (ISBN: 81-85680-42-6). Price of the book has been fixed Rs. 600/- by the publisher.

3. Carbohydrate Metabolism: A Biotechnological perspective (2001) by Dr. Anil Kumar, Agrotech Publishing Academy, Udaipur. (ISBN: 81-85680-46-9) Price has been fixed Rs.400/- by the publisher.

4. Advanced Topics in Molecular Biology (2001) by Dr. Anil Kumar and Dr. A. K.Srivastava, Horizon Scientific Press, UK. (ISBN: 1-898486-28-X). Price has been fixed US$ 150/- (or Sterling pound 80.00) by the publisher.

5. Text Book of Biotechnology (2003) by Dr. Anil Kumar and Ms. Priti Maheshwari, Agrotech Publishing Academy, Udaipur. (ISBN: 81-85680-73-6). Price has been fixed Rs. 200/- by the publisher.

6. Srivastava, A.K. and Kumar, A. (2005) DNA replication. A Chapter in the book’ Animal Biotechnology. Eds. . Dr. A.K. srivastava & Associates, p. 57-69, Oxford & IBH Press, New Delhi

7. Kumar, A. (2005) Regulation of Gene Expression. A Chapter in Encyclopedia of Molecular Cell Biology & Molecular Medicine ( Meyers, R.A. ed.) , 2nd Edition, Volume 12, p. 23-65, Wiley-VCH Verlag GmbH & Co. KGaA press, Weinheim , Germany

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8. Genetic Engineering (2006) by Dr. Anil Kumar & Neha Garg. Nova Science Publishers Inc., New York, USA ( ISBN No. 1-59454-753-X ). Price has been fixed US$135.00.

9. Kumar, A. and Garg, N. (2008) ‘Enzyme Purification’ A Chapter in e book on Enzymology being prepared by NISCAIR, CSIR, New Delhi http://hdl.handle.net/123456789/735.

10. Kumar, A., Rathore, R.S., Singh R.K. and Garg, S. (2008) Proteomics studies to understand the molecular basis of stress tolerance in plants. In Plant Genomics & Bioinformatics (Rao, G.P., Wagner, C. , Singh, R.K.& Sharma, M. L. eds.) Studium Press LLC, Texas, USA pp. 271-301.

11. Kumar, A. and Garg, S. (2009) Immobilization of Enzymes and Biotechnological Perspective. In Biotechnology Applications ( S.K. Mishra & Pascale Champaign eds.) I K International, New Delhi publisher, p. 39-52.

12. Yadav, S., Garg, N., Garg, S. and Kumar, A. (2010) Plant Transformation Technologies. In Plant Genetic Transformation and Molecular Markers ( Ashwini Kumar Ed.) Pointer publishers, Jaipur. P. 1-32.

13. Yadav, S., Garg, N., Garg, S. and Kumar, A. (2010) Molecular markers for improvement of quality traits in crops . In Plant Genetic Transformation and Molecular Markers ( Ashwini Kumar Ed.) Pointer publishers, Jaipur. P. 199-232.

14. Text Book of Enzymes and Enzyme Technology (2010) by Dr. Anil Kumar & Sarika Garg, Anamaya Publishers, New Delhi & Anshan Ltd., United Kingdom (International edition).

15. Garg, N., Mahatman, K.K. and Kumar, A. (2010) Xylanase: Applications and Biotechnological Aspects. Monograph published by Lambert Academic Publishing AG & Co. KG, Koln, Germany ( ISBN 978-3-8383-7504-5).

16. Kumar, A. (2011) Xylanase and Starch Phosphorylase and their Potential Exploitation. Monograph published by Lambert Academic Publishing AG & Co. KG, Koln, Germany ( ISBN 978-3-8443-3151-6).

17. Mahatman, K.K., Garg, N. and Kumar, A. (2011) Xylanase Production using Solid State Fermentation. Monograph published by Lambert Academic Publishing AG & Co. KG, Koln, Germany ( ISBN 978-3-8465-5893-5).

18. Kumar, A. , Garg, S. and Garg, N. (2012) Regulation of gene expression. A chapter in Epigenetic Regulation and Epigenomics Wiley-VCH Verlag GmbH & Co. KGaA press, Weinheim, Germany, p. 191-249

19. Biochemical Tests: Principles and Protocols (2012) by Anil Kumar, Sarika Garg and Neha Garg Viva Books Pvt. Ltd., New Delhi.

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20. Kumar, A. and Maheshwari, P. (2013) Exploitation of medicinal plants for potential bioactive compounds. Monograph published by Lambert Academic Publishing AG & Co. KG, Koln, Germany ( ISBN 978-3-659-31149-9)

21. Kumar, A. , Garg, S. and Garg, N. (2014) Regulation of gene expression. A chapter in RNA Regulation, Ed. Robert A Meyers, Wiley-VCH Verlag GmbH & Co. KGaA press, Weinheim, Germany, p. 285-343.

22. Kumar, A. and Chordia, N. (2014) Relevance of Biological Databases in Post Genomic Era. A chapter in ‘Emerging Technologies of the 21st Century’ Ed. A.K. Roy, New India Publishing Agency, New Delhi, p. 533-547.

23. Kumar, A. and Tyagi, S. (2014) Next Generation Sequencing Technologies: Relevance in Post Genomic Era. A chapter in ‘Emerging Technologies of the 21st Century’ Ed. A.K. Roy, New India Publishing Agency, New Delhi, p. 41-59.

24. Text Book of Enzymes and Enzyme Technology (2015) by Dr. Anil Kumar & Dr. Sarika Garg, Publisher- MV Learning, London, United Kingdom.

25. Kumar, A. and Dhote, M. (2015) Microbial Associated Phytoremediation Technology for Management of Oil Sludge: Phytoremediation for oil sludge management. A Chapter in ‘Uncovering New Methods for Ecosystem Management Through Bioremediation’ Ed. Shivom Singh Rathore, IGI Global Publishers, USA, p./ 1-28.

26. Kumar, A. and Chordia, N. (2015) In Silico PCR Primer Designing and Validation. A chapter in Methods in Molecular Biology, Ed. Clifton, N.J., Vol. 1275; pp. 143-151, Humana Press, USA.

27. Kumar, A. , Garg, S. and Garg, N. (2015) Regulation of gene expression. A chapter in Synthetic Biology-Advances in Molecular Biology and Medicine. Ed. Robert A Meyers, Wiley- Blackwell, Germany, Vol. 1, p. 61-119.

28. Kumar, A. and Chordia, N. (2016) Bacterial resistance against antibiotics. A chapter in Frontiers in Clinical Drug Research- Antiinfectives. Eds. A. Sajid, G. Arora and V C Kalia, Springer Integrative Biotechnology Series.

29. Kumar, A. (2017) . Botany: Introduction and Basics. In Botany: An introduction to plant biology (ed. S. Garg), Delve Publishing LLC (ISBN-10: 1680957538).

30. Kumar, A. (2017). Plant Tissue Culture: History and Basics. In Plant Tissue Culture: Basic and Applied (ed. S. Garg), Delve Publishing LLC (ISBN-10: 1680957635)

31. Garg, S., Chordia, N. and Kumar, A. (2017) Neurodegenerative Disorders: Present Clinical Drug Research and Future Perspectives. A Chapter in Frontiers in Clinical Drug ResearchAnti-infectives. Ed. Atta-Ur-Rahman, Bentham Science Publishers.

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32. Chordia, N. and Kumar, A. (2017) In silico approaches for determination of anti-infective drug targets. A Chapter in Frontiers in Anti-infective Drug Discovery. Eds. Atta-UrRahman and M Iqbal Choudhary, Bentham Science Publishers.

33. Garg, S. and Kumar, A. (2018) Introduction to Polymerase Chain Reaction. In Applications of Polymerase Chain Reaction (Ed. S. Garg), Arcler Press, Canada (ISBN: 9781773611235)

34. Garg, S. and Kumar, A. (2018) Industrial Enzymes: A Brief Review. In Commercially Important Enzymes (Ed. S. Garg), Delve Publishing, Canada (ISBN: 9781773611198)

35. Garg, S. and Kumar, A. (2018) The Basics of Biofuels Production. In Current Scenario in Biofuels Production (Ed. S. Garg), Delve Publishing, Canada (ISBN: 9781773611228)

36. Garg, S., Chordia, N. and Kumar, A. (2018) Basic Aspects of Plant Host Parasite Relationship. In Plant Host Parasite Relationship (Ed. S. Garg), Delve Publishing, Canada (ISBN: 9781773611211)

37. Garg, S. and Kumar, A. (2018) Secondary Metabolites: Natural Antimicrobial agents. In Secondary Metabolites: Natural Antimicrobial Agents (Ed. S. Garg), Delve Publishing, Canada (ISBN: 9781773611204)

38. Garg, S. and Kumar, A. (2018) Introduction to Biofuels Production. In Advances in Biofuels Production (Eds. Kumar, A. & Garg, S.), Nova Science Publishers Inc., New York, USA.

39. Bhagwat, S. and Kumar, A. (2018) Importance of Cellulosic Bioethanol and Pre-treatment Methods for Separating Lignin from Lignocellulosic Biomass. In Advances in Biofuels Production (Eds. Kumar, A. & Garg, S.), Nova Science Publishers Inc., New York, USA.

40. Bhagwat, S. and Kumar, A. (2018) Hexose Fermentation for Ethanol Production. . In Advances in Biofuels Production (Eds. Kumar, A. & Garg, S.), Nova Science Publishers Inc., New York, USA.

41. Chordia, N. and Kumar, A. (2018) Biofuel Production from Pentose Sugars. In Advances in Biofuels Production (Eds. Kumar, A. and Garg, S.), Nova Science Publishers Inc., New York, USA.

42. Advances in Biofuels Production (2018) Edited by Dr. Anil Kumar & Dr. Sarika Garg, Publisher-Nova Science Inc., New York, USA.

43. S Tomar, B Singh and A Jajoo (2019) Effects of organic pollutants on photosynthesis. Book Chapter, Publisher John Wiley, UK, pp 1-26.

44. S Mathur, P Raikalal, A Jajoo (2019) Physiological effects of various abiotic stresses on wheat. Book Chapter in the Book “Wheat Production in Changing environment” Springer Publishers, pp 31-62.

45. M Patidar, A Nighojkar, S Nighojkar and A Kumar (2019) Purification and Characterization of Pectin Methylesterase Produced in Solid State Fermentation by Aspergillus tubingensis. Book

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Chapter, Publisher Hooghly, India.

46. M Sharma and A Kumar (2019) Xylanase: An Overview. Book Chapter, Publisher Hooghly, India.

47. S Tomar, B Singh, A Jajoo (2019) Effects of organic pollutants on photosynthesis. Book Chapter, Publisher John Wiley, UK. In Press.

48. S Mathur, P Raikalal, A Jajoo (2019) Physiological effects of various abiotic stresses on wheat. Book Chapter, Springer Publishers. In Press.

49. Introduction to Biofuels Production. A chapter in Advances in Biofuel Production (A. Kumar, S. Garg, Eds.). Garg, S. and Kumar, A. Nova Science Publishers Inc., New York, USA. pp. 1-15, 2019 (ISBN: 978-1-53614-671-4).

50. Importance of Cellulosic Bioethanol and Pre-treatment Methods for Separating Lignin from Lignocellulosic Biomass. A chapter in Advances in Biofuel Production (A. Kumar, S. Garg, Eds.). Bhagwat, S. and Kumar, A. Nova Science Publishers Inc., New York, USA. pp. 17-40, 2019 (ISBN: 978-1-53614-671-4).

51. Hexose Fermentation for Ethanol Production. A chapter in Advances in Biofuel Production (A. Kumar, S. Garg, Eds.). Bhagwat, S. and Kumar, A. Nova Science Publishers Inc., New York, USA. pp. 41-53, 2019 (ISBN: 978-1-53614-671-4).

52. Biofuel Production from Pentose Sugars. A chapter in Advances in Biofuel Production (A. Kumar, S. Garg, Eds.). Chordia, N. and Kumar, A. Nova Science Publishers Inc., New York, USA. pp. 55-79, 2019 (ISBN: 978-1-53614-671-4).

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Conference and other events organized in last five years

1. National Seminar on “Role of Biotechnology in Human Welfare” held on Jan 23rd-24th, 2014.

2. Hands on training entitled “Enzymes and Enzyme Technology” April 02nd – 16th, 2014 sponsored by the M.P. Biotechnology Council, Bhopal.

3. International Conference “Emerging Challenges in Biotechnology, Human Health and Environment” held on Dec 18th -20th, 2014.

4. Hands on training entitled “Enzymes and Enzyme Technology” July 20th - August 05th, 2015 sponsored by the M.P. Biotechnology Council, Bhopal.

5. International Conference on “Scenario of Biotechnology in 21st Century” March 10th – 12th, 2016.

6. Hands on training entitled “Enzymes and Enzyme Technology” July 20th - Aug 05th, 2016 sponsored by the M.P. Biotechnology Council, Bhopal.

7. National Conference on “Developing Strategies and Institutions for Mahseer Conservation in India" September 09th - 11th, 2016.

8. Hands on training entitled “Enzymes and Enzyme Technology” conducted from October 23rd - November 08th, 2017 sponsored by the M.P. Biotechnology Council, Bhopal.

9. Hands on Training Program “Basic Techniques in Animal Tissue Culture” (12th November – 15th November, 2018) funded by UGC-XII Plan Grant of the University.

10. Seminar on “Introduction to Realtime PCR” on 17th December 2018 in collaboration with Agilent Technologies.

Several committees with active participation of students and faculty members are formed for smooth functioning of the department.

Anti Ragging Committee.

Cultural Committee.

Sports Committee.

Garden Committee.

Lab Management.

Seminar.

Academic Quality Review.

Student Grievance Cell.

Women Cell.

Library Cell.

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BIOINFORMATICS SUB-CENTRE

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Profile

The Bioinformatics Sub-Centre (Distributed Information Sub-Centre) is housed in the School of Biotechnology of the University. The Distributed Information Sub-Centre has been established in Devi Ahilya University, Indore in 1993 with the help of funds provided by the Department of Biotechnology, Ministry of Science and Technology, Government of India as a part of the nation-wide Biotechnology Information System (BTIS) Network. Bioinformatics Sub-Centre is functioning with grace providing facilities to the users and developing databases and application software for the scientific community.

Proposed activities for 2018-19:

Research

We are actively engaged in diversified areas of biology and trying to address various complex issues including identification and characterization of NBS-LRR resistant genes in Soybean and drug designing for various diseases and metabolic disorders. We started identifying putative targets for various bacterial infections. We are trying to find an in silico interacting network between ageing and cardiovascular diseases.

A two years M.Sc. course in Bioinformatics was started from the academic session 2009-2010 by the University.

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DEMP

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SSPred

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Predict Bias

PredictBias is an web baesd application which assists in the identification of genomic and

pathogenicity islands in prokaryotes.

GGRP

GGRP is an independent java based tool which has been developed to facilitate GenBank genome entry into separate gene wise fragmented scanning and manipulations.

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MTGenomeDB

Web enabled secondary database comprising the genomic and proteomic data of five strains of Mycobacterium tuberculosis (H37Rv, CDC1551, Avium, Leprae and bovis) has been developed . All the proteins coded are classified into 100 functional categories, which will enable user to find out a set of genes/proteins involved in a specific function. It also has the facility for comparative genome analysis of all the five strains of Mycobacterium tuberculosis.

ResCut: A Web based program to find out restriction enzyme s cutting site in a given nucleotide sequence.

AnaSeq: A Web based program to analyze the effect of mutation (insertion, deletion, point) on the translation product of a nucleotide sequence with BLAST facility.

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Orchid DB

It is a database of Indian orchids. Because of tremendous economic importance, aesthetic value and medicinal importance of orchids, this project has been taken up. It is Useful to the researchers, conservationists & nterpreneurs working on orchids. It contains morphological, taxonomic & phytogeographic data about Orchids.

PCR RECIPE

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PCR is a technique capable of amplification of even a small amount of DNA upto a billion folds. The DNA fragments (amplicons) generated by conventional PCR or by the modified methods of this technique are extensively used to address a variety of issues related to biology, medicine and forensic sciences. Researchers generally make PCR master mix tube while setting up PCR for a large number of reactions as dispensing all the components in individual tubes is labor-intensive, time consuming and uneconomical. It requires a large number of pipette tips, tubes etc. Repeated pipetting also adds on to the chances of error as well as contamination, when small volumes are being transferred. Large number of stand alone and web based online software are available for designing of PCR primers and optimization of reaction conditions. We have developed a software for calculation of amount of different components of PCR mixture to be added to the master mix and then amount to be dispensed into the individual tubes. It has the advantages of ease of calculation and record keeping along with user friendly interface. The software is developed using Microsoft Visual Basic 6.0 and can be run on Windows 95/98 and NT. A research paper has been published (Singh, V.K. & Kumar, A. (2000) PCR Recipe: Software for setting up PCR reactions', Biotechnology Software and Internet Report 1, 276-277).

OLREA

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Protein and Nucleic acid sequence analyses (Restriction enzyme analysis and motif analysis) are important analytical functions for molecular biologists, which can be done faster, and efficiently using computer programs. We have developed a JAVA based software for on line restriction enzyme analysis of DNA sequence. It can do on line restriction enzyme analysis of DNA sequence using database of 900 restriction enzymes as stated in REBASE. It can give the output in all three standard formats i.e sequence, table and map. This also provides a list of non-cutters. We have found that the algorithm

used for the analysis of restriction sites is fastest known till date. This software will be made available on our website or can be installed for PC based use. This software can be modified to take protein sequence as input and scan it for motifs. It can also be used for analysis of general properties of DNA and proteins like molecular weight, hydrophobicity, hydrophilicity and secondary structures of these molecules. Software has been recognized internationally and a research paper has been published (Singh, V.K.,Pathe,P., and Kumar,A. (2000) OLREA: A faster restriction enzyme analysis using JAVA. Biotechnology Software and Internet Report 1, 278-279). TAXON

A database software for plant taxonomic data management. The current version has enhanced search ability & better method of image storage. It has VB 6.0 as front-end and MS Access 2000 as back-end.

Publication: Samanta, J. and Kumar, A. (2001) TAXON: A Software package for the Management of Plant Database using Visual Basic. Biotechnology Software andInternet Report. 2(5), 201-203.

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Services Provided:

Since July 1995, Centre is continuously providing services to all the interested users. Centre is also providing facility of Fax and Computers along with printer to the entire university members (Fax incoming facility to entire university and outgoing facility mainly School of Biotechnology; of course, many other departments have also used the outgoing facility). Since VSAT is installed as central facility for entire university, it is extensively used. Bioinformatics Sub-Centre is functioning with grace providing facilities to the users and developing databases and application software for the scientific community.

Activities

Carrying out research and development in the field of Bioinformatics. This includes development and up gradation of Bioinformatics software tools, databases, software for routine activities of the centre.

Providing services to Departments of Universities and other educational Research Institutions, Government Departments, R & D units of Industries.

Conducting short-term training programs/workshops in various areas of Bioinformatics.

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Following is the list of the publications where computational facilities of Bioinformatics Sub-Centre were used. The facilities of the centre have also been acknowledged in the publications:

Research Publications

1. Chordia, N,. Jain P., and Hardia P., (2019) Interactome analysis for indentification of common drug target in salmonella species. J Health Med Informat (in press).

2. Chordia, N., Patidar T., and Hardia P. (2019) In Silico Identification of Interaction between Ageing and Cardiovascular Disease Genes. J Health Med Informat 10:2DOI: 10.4172/2157-7420.1000329.

3. Chordia, N. and Kumar, A. (2018) Biofuel Production from Pentose Sugars. In Advances in Biofuels Production (Eds. Kumar, A. and Garg, S.), Nova Science Publishers Inc., New York, USA.

4. Garg, S., Chordia, N. and Kumar, A. (2018) Basic Aspects of Plant Host Parasite Relationship. In Plant Host Parasite Relationship (Ed. S. Garg), Delve Publishing, Canada (ISBN: 9781773611211).

5. Bhagwat, S. and Kumar, A. (2017) Design and Optimization of Enzymatic Saccharification for Bioethanol Production from Parthenium hysterophorus Biomass using Response Surface Methodology. Intl. J. Renew. Energ. Technol. 8, 154-170.

6. Chordia, N. and Kumar, A. (2017) In silico approaches for determination of anti-infective drug targets. A Chapter in Frontiers in Anti-infective Drug Discovery. Eds. Atta-Ur-Rahman and M Iqbal Choudhary, Vol. 5, pp. 150-193, Bentham Science Publishers. (Invited Chapter). DOI: 10.2174/97816810829121170501; eISBN: 978-1-68108-291-2, 2017; ISBN: 978-1-68108-292-9;

ISSN: 2451-9162 (Print); ISSN: 1879-663X.

7. Garg, S., Chordia, N. and Kumar, A. (2017) Neurodegenerative Disorders: Present Clinical Drug Research and Future Perspectives. A Chapter in Frontiers in CNS Drug Discovery. Eds. Atta-Ur-Rahman & M. Iqbal Choudhary, Vol. 3, pp. 72-145, Bentham Science Publishers. (Invited Chapter). DOI: 10.2174/97816810844351170301; eISBN: 978-1-68108-443-5, 2017; ISBN: 978-1-68108-444-2; ISSN: 2542-5056 (Print); ISSN: 1879-6613

8. Kumar, A. and Chordia, N. (2017) Bacterial resistance against antibiotics. A chapter in Drug Resistance in Bacteria, Fungi, Malaria and Cancer Eds. A. Sajid, G. Arora and V C Kalia, pp. 171-192, Springer Integrative Biotechnology Series.

9. Bhagwat, S., Khaire, K., Tiwari, S. and Kumar, A. (2016) Comparison of various pretreatments of biomass for increased enzymatic saccharification for the production of biofuel. Intl. J. Sci. Environ. 5, 2596-2604.

10. Ratnaparkhe, S., Ratnaparkhe, M.B., Jaiswal, A.K. and Kumar, A. (2016) Strain Engineering For Improved Bio-fuel Production. Current Metabolomics 4, 38-48.

11. Bhagwat, S., Girma, A. D. and Kumar, A. (2016) Statistical Optimization of Enzymatic Saccharification of Acid Pre-treated Parthenium hysterophorus Biomass using Response

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Surface Methodology. Biofuels 7, 501-509.

12. Parmar HS, Assaiya A, Agrawal R, Tiwari S, Mufti I, Jain N, Manivannan E, Banerjee T, Kumar A [2016]. Inhibition of Aβ (1-42) oligomerization, fibrillization and acetylcholinesterase activity by some anti-inflammatory drugs: An in vitro study. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry. [Epub ahead of print, PMID: 28034279]

13. Chordia, N., Choudhary, S. and Kumar, A. (2016) Identification of Potential Vaccine candidates from Rickettsia species.: A Reverse Vaccinology Approach. BAOJ Biotechnology 1, 006.

14. Nijampurkar, B., Qureshi, F., Jain, N., Banerjee, T., Kumar, A. and Parmar, H.S., (2015). Anti-inflammatory role of thyroid hormones on rat air pouch model of inflammation. Inflammation & allergy drug targets.

15. Jain, R., Jain, N. and Kumar, A. (2015) Structural prediction, glucose-1-phosphate interaction and influence of broad leaves herbicides on spinach leaves α-glucan phosphorylase: An in silico study. Bioeng. Biosci. 3, 51-59.

16. Yadav R., Chordia N., Kumar A., Shobha S. (2015). Identification of Targetable Virulence Factor and Drug Screening For Bacterial Pneumonia. IOSR Journal of Phramacy and Biological Sciences : 10(2) : 20-24.

17. Barh, D., Kamapantula, B., Jain, N., Nalluri, J., Bhattacharya, A., Juneja, L., Barve, N., Tiwari, S., Miyoshi, A., Azevedo, V., Blum, K., Kumar, A., Silva, A. and Ghosh, P. (2015) miRegulone: a Knowledge base of miRNA regulomics and analysis. Scientific Reports in press Doi: 10.1038/srep12832.

18. Jain, R., Jain, N. and Kumar, A. (2015) Structural prediction, glucose-1-phosphate interaction and influence of broad leaves herbicides on spinach leaves α-glucan phosphorylase: An in silico study. Bioeng. Biosci. 3, 51-59.

19. Chordia, N., Sharma, N. and Kumar, A. (2015) An Interactomic approach for Identification of Putative Drug Targets in Listeria monocytogenes. Intl. J. Bioinform. Res. Appl. 11, 315-325.

20. Parmar H.S., Bhinchar M.K., Bhatia M., Chordia N., Raval I., Chouhan D.S., Manivannan E., Jatwa R, Kumar A. (2014). Study on gluco-regulatory potential of glimepiride sulphonamide using in silico, in vitro and in vivo approaches. Current Pharmaceutical design: 20 ;20(32):5212-7.

21. Sharma, M., Mehta, S. and Kumar, A. (2013) Purification and characterization of alkaline xylanase secreted from Paenibacillus macquariensis. Adv. Microbiol. 3, 32-41.

22. Barh D, Gupta K, Jain N, Khatri G, León-Sicairos N, Canizalez-Roman A, Tiwari S, Verma A, Rahangdale S, Shah Hassan S, dos Santos AR, Ali A, Guimarães LC, Thiago Jucá Ramos R, Devarapalli P, Barve N, Bakhtiar M, Kumavath R, Ghosh P, Miyoshi A, Silva A, Kumar A, Misra AN, Blum K, Baumbach J, Azevedo V. (2013). Conserved host–pathogen PPIs: Globally conserved inter-species bacterial PPIs based conserved host-pathogen interactome derived novel target in C. pseudotuberculosis, C. diphtheriae, M. tuberculosis, C. ulcerans, Y. pestis, and E. coli targeted by Piper betel compounds. Integrative Biology; DOI: 10.1039/C2IB20206A.

23. Barh D., Jain N., Tiwari S., Field J. K., Padin-Iruegas E., Ruibal A., López R., Herranz M.,

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Bhattacharya A., Juneja L., Viero C., Silva A., Miyoshi A., Kumar A., Blum K., Azevedo V, Ghosh P. and Liloglou T. (2013). A novel in silico reverse-transcriptomics-based identification and blood-based validation of a panel of sub-type specific biomarkers in lung cancer. BMC Genomics, 14(Suppl 6), S5.

24. Barh, D., Barve, N., Gupta, K.K., Chandra, S., Jain, N., Tiwari, S., Sicairos, N.L., Canizalez-Roman, A., dos-Santos, A.R., Almeida, S., Ramos, R.T.J., de- Abreu, A.C., Carneiro, A.R., Soares, S.C., Castro, T.L.P., Miyoshi, A., Silva, A., Kumar, A., Misra, A.N., Blum, K., Braverman, E.R. and Azevedo, V. (2013) Exoproteome and secretome derived broad spectrum novel drug and vaccine candidates in Vibrio cholera targeted by Piper betel derived compounds. PLOS One.

25. Hollmann, A., Saviello, M., Delfederico, L., Luerce, T.D., Barh, D., Jain, N., Tiwari, S., Chandra, S., Gupta, K.K., Zambare, V., Kumar, A., Christopher, L., Misra, A.N., Kumavath, R.N. Azevedo, V., Semorile, L., Miyoshi, A. (2012) Tight controlled expression and secretion of Lactobacillus brevis SlpA in Lactobacillus lactis. Biotechnology Letters. 34, 1275-1281.

26. Barh, D., Barve, N., Gupta, K.K., Chandra, S., Jain, N., Tiwari, S., Sicairos, N.L., Canizalez-Roman, A., dos-Santos, A.R., Almeida, S., Ramos, R.T.J., de- Abreu, A.C., Carneiro, A.R., Soares, S.C., Castro, T.L.P., Miyoshi, A., Silva, A., Kumar, A., Misra, A.N., Blum, K., Braverman, E.R. and Azevedo, V. (2012) Exoproteome and secretome derived broad spectrum novel drug and vaccine candidates in Vibrio cholera targeted by Piper betel derived compounds. PLOS One.

27. Barh D, Barve N, Gupta K, Chandra S, Jain N, Verma A, Khatri G, Rahangdale S, Santos AR, Kumar A, Azevedo V, Silva A. Global protein-protein interaction derived effective targets in most common pathogenic bacteria. [Integrative Biology] [Impact Factor 4.5].

28. Hassan, S., Schneider, M.P., Ramos, R.T., Carneiro, A., Lima, A.R. , Guimarães, L.C., Ali, A., Bakhtiar, S., Pereira, U., Santos, A., Soares, S.C., Dorella, F., Pinto, A., Ribeiro, D., Barbosa, M.S., Almeida, S., Abreu, V.A., Aburjaile, F., Fiaux, K.K., Barbosa, E.G., Diniz, C., Rocha, F., Saxena, R., Tiwari, S., Zambare, V., Ghosh, P., Pacheco, L.G., Dowson, C., Kumar, A., Barh, D., Miyoshi, A., Azevedo, V. and Silva, A. (2012) Whole genome sequence of Corynebacterium pseudotuberculosis strain 162 isolated from camel. J. Bacteriol. 194, 5718-5719.

29. Tiwari, R. and Kumar, A. (2012) Starch phosphorylase: Biochemical and Biotechnological perspectives. Biotechnol. Mol. Biol. Rev. 7, 69-83.

30. Sethi, A., Parmar, H.S. and Kumar, A. (2011) Atherogenic diet induced diabetic mellitus:Antidiabetic role of aspirin. Basic Clin. Pharmacol. Toxicol. 108, 371-377.

31. Pundhir, S. and Kumar, A. (2011) SSPred: A prediction server based on SVM for the identification and classification of proteins involved in bacterial secretion systems. Bioinformation 6, 380-382.

32. Barh, D., Jain, N., Tiwari, S., D’Afonseca, V., Li, L., Ali, A., Santos, A.R., Guimaraes, L.C., Soares, S.D.C., Miyoshi, A., Bhattacharjee, A., Misra, A.N., Silva, A., Kumar, A. and Azevedo, V. (2011) A novel comparative genomics analysis for common drug and vaccine targets in Cornebacterium pseudotuberculosis and other CMN group of human pathogens. Chemical Biol.

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Drug Design 78, 73-84.

33. Barh, D., Tiwari, S., Jain, N., Ali, A., Santos, A.R., Misra, A.N., Azevedo, V. and Kumar, A. (2011) In silico subtractive genomics for target identification in human bacterial pathogens. Drug Development Res. 72, 162-177.

34. Maheshwari, P. and Kumar, A. (2010) RAPD analysis of UB-B induced variation in somaclones of Veronia cinerea. Genes Genomes Genomics 4, 58-64.

35. Mahatman, K.K. and Kumar, A. (2010) Xylanase production using alkalo-thermophilic Bacillus halodurans KR-1 by solid state fermentation. Curr. Trends Biotechnol. Pharmacy 4, 871-880.

36. Barh, D., Misra, A. N. , Kumar, A. And Vasco, A. (2010) A novel strategy of epitope design in Neisseria gonorrhoeae. Bioinformation 5, 77-85.

37. Barh, D., Misra, A. N. and Kumar, A. (2010) In Silico Identification of dual ability of N. gonorrhoeae ddl for developing drug and vaccine against pathogenic Neisseria and other human pathogens. J. Proteomics Bioinformatics 3, 082-090. doi: 10.4172/jpb.1000125.

38. Maheshwari, P. and Kumar, A. (2009) Antimicrobial activity of Abelmoschus moschatus leaf extracts. Curr. Trends Biotech. Pharm. 3, 260-266.

39. Rathore, R. S., Garg, N., Garg, S. and Kumar, A. (2009) Starch Phosphorylase: Role in Starch Metabolism and Biotechnological Applications. Crirical Rev. Biotechnology 29, 214-224.

40. Garg, S., Ali, R. and Kumar, A. (2009) Production of Alkaline Xylanase by an Alkalo-thermophilic Bacteria, Bacillus halodurans, MTCC 9512 Isolated from Dung. Curr. Trends Biotech. Pharm. 3, 90-96.

41. Barh D., Kumar, A. and Misra A.N., (2009) Genomic target database (GTB): A database of potential targets in human pathogenic bacteria. Bioinformation, 4, 50-51.

42. Barh D., Kumar, A., Chatterjee S. and Liloglou T. (2009) Molecular features, markers, drug targets and prospective therapeutics in cardiac myxoma. Current Cancer Drug Targets 9, 705-716.

43. Barh D. and Kumar, A. (2009) In silico identification of candidate drug and vaccine targets from various pathways in Neiseria gonorrhoeae. In Silico Biology 9, 0019.

44. Maheshwari, P., Garg, S. and Kumar, A. (2008) Taxoids: Biosynthesis and in vitro production. Biotechnology Molecular Biology Reviews 3(4), 71-87.

45. Garg, N. and Kumar, A. (2008) Immobilization of starch phosphorylase from cabbage leaves: Production of glucose-1-phosphate. Brazilian J. Chem. Eng. 25, 229-235.

46. Garg, N., Pundhir, S., Prakash, A. & Kumar, A. (2008) PCR Primer Design: DREB Genes. J. Comp. Sci. Syst. Biol. 1, 21-40.

47. Garg, N., Pundhir, S., Prakash, A. and Kumar, A. (2008) Primer designing for DREB1A, A cold induced gene. J. Proteomics Bioinformatics. 1(1), 37-46.

48. Pundhir, S., Vijayvargiya, H. and Kumar, A. (2008) PredictBias: a server for the identification of genomic and pathogenicity islands in prokaryotes. In Silico Biology 8, 0019.

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49. Garg, S. and Kumar, A. (2007) Immobilization of starch phosphorylase from seeds of Indian millet (Pennisetum typhoides) variety KB 560. African J. Biotech. 6, 2715-2720.

50. Maheshwari, P., Songara, P., Kumar, S., Jain, P., Srivastava, K. and Kumar, A. (2007) Alkaloid production in Vernonia cinerea: Callus, cell suspension and root cultures. Biotechnology Journal. 2, 1026-1032.

51. Garg, S., Sohani, N., Pundhir, S. and Kumar, A. (2007) Primer Designing for Endo-1, 4- -xylanase gene. J. Cell Tissue & Research 7, 1147-1154.

52. Maheshwari, P. and Kumar, A. (2006) Organogenesis, shoot regeneration and flowering response of Vernonia cinerea to different auxin / cytokinin combinations. In Vitro Cellular & Developmental Biology – Plant 42, 589-595.

53. Garg, N. and Kumar, A. (2006) Primer designing of DREB2A, a drought resistant gene in Glycine max. J. Cell Tissue Res. 6, 807-813.

54. Khan, I., Desai, D.V. and Kumar, A. (2004) Carbochips- a new energy for old biobuilder. J.Biosci. Bioeng. 98, 331-337.

55. Banerjee, P.P., Dass, S. V., Mathew, A., Parekh, V.V., Prasad, D.V.R., Joshi, B., Kumar, A. and Mishra, G.C. (2002) Evidence for GP96, a stress protein, functions as Th2 specific costimulatory molecule. J. Immunology 169, 3507-3518.

56. Prasad, D.V.R., Parekh, V.V., Joshi, B.N., Banerjee, P.P., Parab, P., Chattopadhyay, S., Kumar, A. and Mishra, G.C. (2002) The Th1-specific costimulatory molecule, M150, is a posttranslational isoform of LAMP-1. J. Immunology 169, 1801-1809.

57. Bhat, S., Maheshwari, P., Kumar, S. and Kumar, A. (2002) Mentha species: In vitro Regeneration and Genetic Transformation. Mol. Biol. Today 3, 11-23.

58. Singh, V.K. and Kumar, A. (2001) PCR Primer Design. Mol. Biol. Today 2, 27-32.

59. Singh, V.K., Mangalam, A.K., Kumar, A., and Naik, S., (2001) Universal primers can amplify tumor necrosis factor gene across species. Mol. Biol. Today 2, 11-12.

60. Gupta A, Singh V K, Qazi G N and Kumar A (2001) Gluconobacter oxydans: A Biotechnological perspective, J Mol. Microbiol. Biotechnol. 3, 445-456. Review.

61. Samanta, J. and Kumar, A. (2001) TAXON: A Software package for the Management of Plant Database using Visual Basic. Biotechnology Software and Internet Report. 2 (5), 201-203.

62. Singh,V.K., Govindrajan, R., Naik, S. and Kumar, A. (2000) The effect of Hairpin structure on PCR amplification efficiency., Mol. Biol. Today 1 (3), 67-69.

63. Singh, V.K. and Kumar A (2000) OLREA: A faster restriction enzyme analysis using JAVA. Biotechnology software and Internet Journal, 1, 278-279.

64. Singh, V.K. and Kumar A (2000) PCR Recipe: Software for setting up PCR reactions, Biotechnology software and Internet Journal 1, 276-277.

65. Mishra, B.N. Singh, S.P. and Kumar A. (1998) Start-up and operational behavior of an anaerobic

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fixed bed bioreactor treating pharmaceutical waste water. Crop Research, 16 (3), 395-401. (MATLAB USED)

66. Mishra, B.N. and Kumar, A. (1998) Operational Characteristics of anaerobic fixed bed reactors : wastewater treatment and methane production J. Nature Conservation,10 37-45. (MATLAB USED)

67. Singh, V.K. and Kumar, A. (1998) Production and purification of extracellular cellulase from Bacillus brevis VS-1. Biochem.Mol. Biol. International 45 443-452.

68. Nighojkar, S.A. & Kumar, A. (1997) Starch Phosphorylase: Biochemical, Molecular and Biotechnological aspects. The Genetic Engineer & Biotechnologist, 17 189-2-2.

69. Mishra, B.N. and Kumar A. (1997) Anaerobic treatment of potato-starch wastewater using a Foam bed bioreactor. The Genetic Engineer & Biotechnologist, 17, 165-173.

70. Mishra, B.N., Singh S.P. & Kumar A. (1997) A biofilm model for fixed bed anaerobic reactors: Performance analysis considering diffusional resistances and axial dispersion. The Genetic Engineer and Biotechnologist 17 5-21. (MATLAB USED)

71. Kumar, A. & Mishra, B.N. (1997) Primer Premier Biotechnology Software J. 31-33, review.

72. Nighojkar A., Srivastava S., & Kumar A., (1997) Pectin Carbohydrates and their commedrcial uses. J. Nature conservation 9 141-151.

73. Upadhye, S and Kumar, A. (1996) Immobilization of starch phosphorylase from bengal gram seeds: Production of glucose-1-phosphate. The Genetic Engineer and Biotechnologist 16, 145-151.

74. Srivastava, S. Nighojkar, A. and Kumar, A. (1996) Demethoxylation of Pectin using immobilized Cuscuta reflexa pectin methylesterase. The Genetic Engineer and Biotechnologist 16, 73-80.

75. Nighojkar, A. Srivastava, A. and Kumar, A. (1996) Endopolygalacturonase from germinating Vigna sinensis seeds Plant Physiol Biochem 23, 1-7.

76. Srivastava, S. Nighojkar, A. and Kumar, A. (1996) Immobilization of Cuscuta reflexa Starch Phosphorylase: Production of glucose-1-phosphate using bioreactors. J.Ferment Bioeng 81, 355-357.

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Bioinformatics research papers presented/communicated in various National/International

conferences

1. Garg, N. and Kumar, A. (2006) Primer designing of DREB2A, a drought resistant gene in soybean. 93rd Indian Science Congress Association meeting, Hyderabad, Jan. 3-7, 2006.

2. Pundhir, S., Vijayvargiya, H. and Kumar, A. (2006) Poster presentation. Predict Bias: Detection of Pathogenicity Islands in Pathogenic bacteria, International Conference in Bioinformatics (InCoB2006), New Delhi, Dec. 18-20, 2006.

3. Garg, S., Sohani, N., Pundhir, S. and Kumar, A. (2006) Primer Designing for Endo-1,4- - xylanase gene, Oral Presentation, National Conference on Biotechnology, Science & Environment, Indore, Dec. 28-29, 2006.

4. Pundhir S. and Kumar, A. In Sillico Classification of Virulence factors, National Conference on Biotechnology, Science & Environment, Indore, Dec. 28-29, 2006. (Best paper award).

5. Pundhir, S. and Kumar, A. (2008)SSPred: A prediction server based on SVM for the identification & classification of proteins involved in bacterial secretion systems. Poster Presentation. HUGO s 13th Human Genome Meet, Hyderabad, Sept. 27-30, 2008.

6. Pundhir, S., Vijayvargiya, H. and Kumar, A., (2008) PredictBias: a server for the identification of genomic and pathogenicity islands in prokaryotes. Oral Presentation. International Conference on Bioinformatics(Incob2008), Taipei, Taiwan. Oct. 20-23, 2008.

7. Pundhir, S. and Kumar, A. (2008) SSPred: A prediction server based on SVM for the identification & classification of proteins involved in bacterial secretion systems. Poster Presentation. International Conference on Bioinformatics(Incob2008), Taipei, Taiwan. Oct. 20-23, 2008.

8. Yadav K., Pundhir, S., Singh T.R. and Kumar, A. (2009) GGRP: GenBank Genome Record Parser, Poster presented in 5th World congress of Cellular and Molecular Biology, Indore, India Nov., 2-5, 2009.

9. Singh D., Chandra S., and Singh T.R. (2009) In Silico prediction of T-Cell epitopes from outer membrane protein of outer membrane vesicles of Neissieria meningitides serogroup BC (MC 58). Oral Presentation. Ist IFIP International Conference on

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Bioinformatics, Surat, India Mar. 25-28, 2010.

10. Singh D., Chandra S., and Singh T.R. (2009) Homology Modeling of Salmonella Typhi Ty2 enolase and its docking studies. Oral Presentation. Ist IFIP International Conference on Bioinformatics Surat, India Mar. 25-28, 2010.

11. Kekre, A., Panwar, D.S., Desai, D.V., Sharma, A., Vijayvargiya, H., and Kumar, A. (2010) OrchidDB: A taxonomical database of Orchid species of Indian origin. Poster Presentation. 1st IFIP International Conference on Bioinformatics Surat, India March 25-28,2010.

Successful Organization of Training programmes, Workshops and Symposium:

Workshop on "Current Computing Trends in Bioinformatics" January 18-20, 1997.

Workshop on "Recent Advances in Bioinformatics" January 17-19, 1998.

Workshop on "Perspectives in Bioinformatics and Biotechnology" January 25-27, 1999.

Centre organized a National Symposium on Bioinformatics entitled "Trends in Protein and Nucleic Acid Sequence Analyses" on October 30-31st, 1999.

One day Workshop on “Internet for University Teachers and staff” March 5, 2000.

Workshop on "Bioinformatics in Biological Sciences” November 13-15, 2000.

Workshop on “Computers in Biological Sciences” November 08-10, 2001.

Training programme in Bioinformatics December 17, 2001-January 15, 2002.

Workshop on “Genomics/ Proteomics” January 11-12, 2002.

Workshop on “Computer Basics & Applications” November 13-15, 2002.

Workshop on “Retrieval of Bioinformatics Resources / Databases” January 10-11, 2003.

Workshop on “Computer Basics & Applications in Bioinformatics” November 13-15, 2003.

Workshop on “Genomics / Proteomics” January 16-17, 2004.

Workshop on “Computer Basics & Applications in Biosciences” November 17-19, 2004.

Workshop on “Computer Basics & Applications in Bioinformatics” October 20-22, 2005.

Workshop on “Bioinformatics & Biocomputing” January 19-20, 2006.

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Workshop on “Bioinformatics for Genomics & Proteomics Data Analysis” October 09-13, 2006.

Workshop on “Bioinformatics for Genomics & Proteomics Data Analysis” October 29-November 02, 2007.

Workshop on “Machine Learining Techniques for Bioinformatics Data Analysis” November 04-November 08, 2008.

Workshop on “Structural Bioinformatics & Systems Biology” on Nov. 25-27, 2009.

Workshop on “Computational Biology and Molecular Dynamics” on Jan 20-22, 2011.

Workshop on “Genomics, Proteomics and Bioinformatics” on Aug 29-31, 2013.

Workshop on “Biocomputing and Biomedical Informatics” on Feb 20-21, 2017.

Workshop on "Medicinal Bioinformatics" on Feb. 08-09, 2019

STUDENTS TRAINING:

Seeing the publicity of the Bioinformatics, students have been attracted to this field. In addition to training to the students and other interested persons through workshops now, we have awarded two studentships in Bioinformatics to carry out six month research project at our centre. Seven students did summer training at our centre in the year 1999- 2000. Four students were BE (Comp. Sc.) final year students from Institute of Engineering and Technology, DAVV, Indore, one was M Sc. Life Science final year student from School of Life Scinces, DAVV Indore and one was our own student doing M.Sc. Biotechnology Final year at School of Biotechnology.

We have accepted students of various Institutes for their project work. Centre offered one studentship to a student, for her M.Sc. Biotechnology project in the field of Bioinformatics. She has worked on the Primer Designing of DREB2A, a drought resistant gene in Soybean. She has designed primers using Drought resistant gene DREB2A cDNA clone of glycine max (soybean). Using various software viz. WEB PRIMER, PRIMER INPUT3 she designed 180 primers. Afterwards using permutations and combinations, eight forward and eight reverse primers have been finally designed.

Core Activities

In the next five years, we plan to develop software and database useful in biotechnology research like a comprehensive database of starch phosphorylase and software’s for the whole genome analysis of Prokaryotes.

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A comprehensive hybrid secondary database of Transcription factors, promoters and related entities.

Research going on for discovering new drugs and markers for various human diseases.

We will also continue to impart education in the field of bioinformatics through workshops and training classes.

Computational Facilities

Desktops Pcs, Printers & Scanners

Firewall System: HP Desktop PIV

Computer Desktop: 25+15

Laptop and Notebook: 07

Lasejet/Deskjet Printer : 08

Scanner : 04

Photocopier: 02

Communication Facility

Multimedia Projector 06 nos.

Access to 1 Gbps fiber optic connection provided by the I.T. Centre of the University.

Wi-Fi Connectivity.

Bioinformatics Resources

The DISC has purchased a number of software for research and development. They are: 1) Statistical Software SPSS 15.0 (10 Users).

2) SPSS AMOS 7.0 (1 user)

3) MOE

4) The Cambridge Structural database (CSD).

3) Reference Manager

4) MATLAB 5.0 with the following Application tool boxes:

Neural Network tool box.

Fuzzy logic tool box.

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Partial differential equation tool box.

Symbolic math tool box.

SIMULINK.

5) PROSIS

6) DNASIS

7) Derwent Biotechnology Abstracts from 1982 -2004

A number of software tools and databases have been procured by the Bioinformatics Sub-centre from a number of Organizations and Institutes of international repute. We duly acknowledge the Organizations, Institutes and persons who have liberally permitted the provision of links and usage of their tools, programs, databases for academic purposes.

Sequence analysis software:

BLAST (Different versions),FASTA,CLUSTALW, MultAlin, CLUSTALX, Muft, Muscle, T-Coffee.

Molecular modeling software: Modeller, SwissModel, 3D-JIGSAW, CPH Model, PS2, Protinfo. Evaluation version of HyperChem 7.0 Molecular visualization software:

Swiss PDB Viewer (SPDBV), Rasmol (raswinsx, rw32b2a), Pymol, Chime, Protein Explorer, Chimera, Chemsketch, Argus Lab, Hex, Malip.

Protein Interaction software:AutoDock, Molegro Virtual docker, STRING, Visant, Osprey, Cytoscape. Other activities

Orientation programme for fresher’s Introduction to Biotechnology.

Tree plantation by students and staff.

Cleanliness drive.

Cultural events during conferences.

Other proposed activities

Industrial visits.

Adopting a village school as a social responsibility.

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