Sayre Materia Medica-1

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  • 8/14/2019 Sayre Materia Medica-1


    Sayr e s M a t e r i a M ed i ca - P age 1

  • 8/14/2019 Sayre Materia Medica-1



    The Ninth Revision of the United States Pharmacopoeia, as in no

    previous edition, makes it import an t, an d even necessary, tha t a ll work sof a pha rm aceutical char acter be r evised.

    The last revision of the Pharmacopoeia has required, on the part of therevisers, very exceptiona l work directed toward th e su bject of stan dar ds;and inasmuch as the United States Pharmacopoeia, as well as theNational Formulary, is mentioned in the statute, known as the Foodan d Dru gs Law, th is revision ha s become of great est importa nce.

    Recognizing this, great pains have been taken in the revision of thepresent edition, that the standards, whenever mentioned, shall conformto the legal st an dar d above referr ed to.

    Many changes have been made necessary by the fact that the U.S.P. IXhas deleted fifty-three vegetable drugs and has added, or raised toofficial r ecognit ion , but four of well kn own dr ugs.

    Among the conspicuous changes in U.S.P. IX, is the adoption of Mil(singular), Mils (plural), for cubic centimeter (cc.). This coined word,Milfor Milliliter, is more accurate than cubic centimeter, (cc.) for thethousandth of a liter, which the cubic centimeter was intended to

    express. Throughout this present edition mil and mils have beenused, replacing the less accurate cc.

    The Families of plants yielding organic drugs have been rearranged inthe present volume. The order of arrangement adopted is that which isfollowed by all botanists of any note at the present time, commencingwith the Alg, Fungi, and other cryptogamous growths, the order andsequence of such authors as Engler and Prantl have been practicallyfollowed. This ha s required a n en tire t ra nsposition of th e na tu ra l order sof the former edition.

    The Chapter on Inorganic Chemicals has been enlarged to meet thedemand of many students. Added to this is a brief Chapter onTherapeutic Action, which is intended as a suggestion to students ofhow to expand their knowledge in this direction by reference to otherworks.

    Sayr e s M a t e r i a M ed i ca - P age 2

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    The chapters relating to histological study of plant tissues have beenentirely omitted in the present edition in order to economize space fornew material, and, secondly, because Professor Stevens, formerlyassociated in this work, has published an entirely satisfactory volume

    for class-room work and covered the ground more completely in hisPlan t Ana tomy.

    A Chapter on Serotherapy has been incorporated which, in treatment,while it is concise, it is hoped will meet t he pr esent dema nd of stu dent sof Mat eria Medica, who first mu st ha ve studied th e elemen ts of th is veryextensive subject.

    The a ut hor desires t o ma ke special m ent ion of valuable service ren deredby his as sociate, Mr. Cha s. M. Sterling, who ha s r evised t ha t port ion of

    th e work included in t he var ious chapt ers of Pa rt IV. The au th or r egretsthat he has been obliged to reduce rather than lengthen many articlesin Materia Medica in order that the present volume should not beun duly expan ded.

    L. E. S.

    Sayr e s M a t e r i a M ed i ca - P age 3

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    The pr esent volume is, in a slight degree, a revision of a work writt en bythe author in 1879, entitled Organic Materia Medica and PharmacalBotany. This work has been out of print a number of years, and untilrecently the author has had no time to rewrite it in such a manner asseemed necessar y to bring it u p to the presen t st an dar d; it ha s also beendeemed advisable to change completely the model of the former work.The task now accomplished presents not so much a revision, as a newtreatise.

    Two methods of classification of drugs are here brought into useaclassification according to physical characteristics, and a classificationaccording to botanical relationshipsboth of which are, though,

    occupying separate divisions of the book, so brought together by asystem of nu mbering t ha t t he place of th e dru g in ea ch of th e classes isat once appa rent . The a ut hor would here suggest t ha t t hose who ma keuse of the work in connection with a cabinet of specimens, should havethe containers in the cabinet numbered to accord with numbers in thebook, in order that students may readily find specimens forident ificat ion an d st udy.

    It is perhaps needless to state that the nomenclature and generalcha ra cter of th e text is ma de to conform with th e present st an dar dThe

    United States Pharmacopoeia; but the capitalization of specific namesderived from proper nouns has been discarded, in accordance withpresen t bota nical practice. The descriptive hea ding of each of th e officialdrugs has been in most cases given in the pharmacopoeial language.The unofficial drugs are distinguished in the text by the use of adifferent type and by a different setting of the article from that whichtr eat s of th e official dru gs. In t his conn ection th e aut hor desires to givecredit to Mr. George S. Davis, who has aided in the work by placing atthe author's disposal most excellent material regarding rare unofficialdrugs, and the use of material from his publication, credited under


    The scope of the work, it will be seen, embraces not only the officialdrugs of the vegetable and animal kingdoms, but a vast variety ofunofficial drugs, some of which are of rare occurrence in the market.These have been included because of the greater field this inclusiongives for pharmacal and botanical study; the greater variety of forms

    Sayr e s M a t e r i a M ed i ca - P age 4

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    presented to the student of pharmacognosy, the wider will be his rangeof observat ion. It is hoped th at in th e 624 dru gs ment ioned, th e stu dentor instructor will be able to make a selection which will be ample tosupply material to illustrate the principles of the subject underconsideration. In a work of this size an exhaustive treatment of this

    number of drugs could not be given, but by a brief mention of themmaterial for study is indicated. It may be mentioned in this connectionthat wherever metric measurements are given, these are stated inmillimeters; this has been deemed advisable for the purpose ofcomparison.

    The illustrations included in Part I are taken mainly from Bentley'sManual of Botany, to the author of which our thanks are due. Anexception, however, is found in the drawings of the starches, whichwere prepared from original specimens. The remaining illustrations,

    with t he exception of th ose in th e Cha pter on Anima l Drugs, have beenprepa red u nder th e direction of C. E. McClung, Ph. G., a gradu at e of th eKansas State University School of Pharmacy, class of '92. All thedra wings of the cross-sections ar e dr awn directly from sections prepa redby him, th e cell cont ent s being first rem oved by th e met hod described inAppendix C. It h as been our a im to present th e element s of each dru g inth eir tr ue pr oport ions.. As often as possible, the cells in th eir exact sha peand relative size have been drawn, and in no case has meaninglessshading been employed. For some of the drawings of the medicinalplants credit is given below in the Bibliography. The illustrator has

    kindly furnished a Chapter on Pharmacal Microscopy, which will befoun d in Appen dix C.

    The author is much indebted to Professor Vernon Kellogg forinformation concerning animal drugs used in pharmacy; also forAppendix B, in which h e tr eat s of insects at ta cking dru gs. The dr awingsto illustrate the material furnished by Professor Kellogg are herebycredited to Miss Mar y Wellma n, ar tist .

    For aid in the preparation of, the text in Part I our thanks are due to

    Mr. A. O. Garrett, who, in his university course, has made botany aspecial st udy.

    Appen dix B, upon t he syn thet ic rem edies, is the work of Mr. F. B. Da ins,who has made a specialty of organic chemistry and was instructor inth is subject in the University of Kan sas du ring the year 1894. In th issection the new spelling of chemicals has been adopted only in a few

    Sayr e s M a t e r i a M ed i ca - P age 5

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    To Dr. S. W. Williston, Professor of Physiology and Anatomy, who hasaided in the condensed description of therapeutic action; to Mr. O. H.Pa rk er a nd Mr. William Clark , members of the Sen ior Class of '94, who

    ass isted in t he stu dy of cha ra cter istics from cru de specimens of dru gs inth e open m ar ket; to Mr. W. O. Str oth er, of th e sam e class, who supplieda few dr awings of cross-sections; an d t o Mr. W. F. Newt on , of the jun iorClass , who ma ter ially aided not only in t he st udy of dru g cha ra cterist ics,but also in arr an ging the ma terial, our t ha nks a re due.

    L. E. S.

    Sayr e s M a t e r i a M ed i ca - P age 6

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    Drugs may be arranged in several different ways, to suit the aim andconvenience of the student. The prominent systems of classification incommon u se a re a s follows:

    I. T h e r a p e u t i c a l.This system of class ifica tion is especially valua ble toth e stu dent of medicine. Here t he ph ysiological a ction a nd t her apeu ticalapplicat ion ar e ma de most prominent .

    II. C h e m i c a l .Class ificat ion of orga nic dru gs is not in frequ ent ly basedupon