NIFTY™ is a trademark of BGI. All rights reserved.

For more information about the NIFTY™ test or for further details on the conditions mentioned in this brochure, please visit our website.

www.ni�ytest.com

Alternatively, ask your healthcare provider if NIFTY™ is right for you.

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NIFTY™ Advantages

SAFENon-invasive with no risk of miscarriage

ACCURATEProven 99.5% sensitivity and specificity for detection of trisomy conditions

TRUSTEDOver 300,000 NIFTY tests carried out to date

SIMPLETest from a small 10ml maternal blood sample

99.9%Down syndrome (Trisomy 21)

Edwards syndrome (Trisomy 18)

Patau syndrome (Trisomy 13)

Trisomies

Gender Identification

Sex Chromosome Aneuploidies

Klinefelter syndrome (XXY)

Turner syndrome (Monosomy X)

Triple-X (XXX)

XYY Karyotype

Microdeletion Syndromes

Cri-du-Chat syndrome (5p)

1p36

2q33.1

Male/Female

Testing Options

Where can I get more information?

BROUGHT TO YOU BY:

OVER 300.000 TESTS CARRIED OUT WORLDWIDE

NIFTY™ is a safe, simple and highly accurate blood test that detects the risk of certain genetic conditions, such as Down syndrome, from as

early as week 10 of your pregnancy.

@niftytest_

NIFTY test

Ole Maaløes Vej 32200 Copenhagen NDenmark

Customer services hotline: +45 80 300 800

Email: customerservices@bgidx.com

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What are trisomies?

What is NIFTY™?

Cells usually contain 46 chromosomes arranged in 23 pairs. A trisomy is a medical term used to describe instances when there is an extra copy of a chromosome in some or all of the cells. The presence of the extra chromosome can cause severe congenital physical disabilty and developmental problems. NIFTY™ tests for the three most common trisomies present at birth.

NIFTY™ (Non-Invasive Fetal Trisomy) is a simple, safe and highly accurate prenatal test, which measures the risk for trisomies 21, 18 and 13 with a sensitivity and specificity rate of over 99%. We also offer additional testing options for certain sex chromosomal aneuploidies and microdeletion syndromes. The test is available from as early as week 10 of pregnancy.If you choose to know, the NIFTY™ test can also tell you the gender of your baby.

We know that being pregnant is one of the most exciting periods in a woman’s life, which brings not only great happiness but also considerations regarding the health of your baby. Based on the latest advances in non-invasive prenatal testing and using whole genome sequencing-based technology, the NIFTY™ test is able to accurately tell you the risk of certain genetic conditions, which may affect the health of your baby.

Available from week 10 of pregnancy

Test available for:

Twin Pregnancy (for trisomies only)

IVF Pregnancy

Egg Donor Pregnancy

Turn-around time standard 10 working days

Non-invasivePrenatal testing (NIFTY)

SerumScreening

DiagnosticTesting

Screening test

Non-invasive

Detection rate for Down syndrome 99.5%

False Positive Rate <0.5%

Provides individualised risk score

Gender information and sex chromosome aneuplodies

Condition Estimated Occurence(at birth)

Trisomy 21(Down syndrome)

Trisomy 18(Edwards syndrome)

Trisomy 13(Patau syndrome)

1/700

1/7900

1/9500

How does NIFTY™ work?

Congratulations on your pregnancy! Should I get a NIFTY™ test?

How Does NIPT Differ from Other Prenatal Tests?

Some women have an increased chance of their baby being affected by certain genetic conditions. You should consider a NIFTY™ test if:

you have a personal or family history of a chromosomal condition

you are considered of advanced maternal age

During pregnancy, DNA originating from the baby crosses into the mother’s blood stream. NIFTY™ consists of a small 10ml blood sample taken from the mother as early as week 10 of the pregnancy. From this blood sample cell free fetal DNA is analysed in order to examine the baby’s health and check for too few or too many chromosomes.

you have received an abnormal serum screen test result or ultrasound finding in the1st or 2nd trimester

Source. Oxford Desk Reference: Clinical Genetics by Helen V. Firth and Jane A. Hurst. Oxford University Press, 2005.

Fetal DNA Maternal DNA

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