Robin Wright University of Minnesota. “Such a site would search like Google, recommend like...

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Robin Wrigh University of Minnesot

Transcript of Robin Wright University of Minnesota. “Such a site would search like Google, recommend like...

Robin WrightUniversity of Minnesota

“Such a site would search like Google, recommend like Amazon, vet like Consumer Reports, annotate like Wikipedia. Done well, this interface would provide a core of information, tools, and networks for undergraduate biology educators.”

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First steps

• Peter Bruns (HHMI)• Malcolm Campbell (Davidson College)• Erin Dolan (University of Georgia)• Sarah Elgin (Washington University, St. Louis)• Sarah Goodwin (ASCB, IBioSeminars)• Jo Handelsman (Yale University)• Bill Wood (University of Colorado, Boulder)• Robin Wright (University of Minnesota)

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Why meiosis matters: The Case of the Fatherless SnakeRobin Wright, University of Minnesota

Course(s): Genetics, Cell Biology

Using an interesting case of virgin births in snakes to motivate students to learn the mechanisms of meiosis and develop scientific thinking skills.

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Learning Objectives: • Describe, using diagrams, the sequence of events involving DNA in

meiosis from chromosome duplication through chromosome segregation.

• Explain how meiosis is different from mitosis.• Given an offspring’s genotype, predict the stage(s) of meiosis that

could have been abnormal• Propose a testable hypotheses to explain observations

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Why meiosis matters: The Case of the Fatherless Snake

Robin WrightUniversity of Minnesota

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Probiotics: What’s in a name?Jessamina BlumUniversity of Minnesota

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Learning Objectives • Describe, using diagrams, the sequence of events involving DNA in meiosis from

chromosome duplication through chromosome segregation. Explain how meiosis is different from mitosis.

• Given an offspring’s genotype, predict the stage(s) of meiosis that could have been abnormal

• Propose a testable hypotheses to explain observations

Learning Objectives • Define probiotics and their uses• Explain the current FDA guidelines defining probiotics• Evaluate health claims made by probiotic products using primary literature

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Genetics

Interpreting patterns of inheritance (1)

Chromosome structure and function (3)

Molecular biology of gene function

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Gene linkage and mapping (2)

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Why meiosis matters: The Case of the Fatherless SnakeRobin Wright, University of Minnesota

Learning Objectives • Describe, using diagrams, the sequence of events involving DNA in

meiosis from chromosome duplication through chromosome segregation. Explain how meiosis is different from mitosis.

• Given an offspring’s genotype, predict the stage(s) of meiosis that could have been abnormal

• Propose a testable hypotheses to explain observations

Learning Objectives provided by Genetics Society of America

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Why meiosis matters: The Case of the Fatherless Snake Robin Wright, University of Minnesota

Lesson

Framing Question • What are the mechanisms by which an organism’s genome is passed on to the next generation?

Learning Objectives • Describe, using diagrams, the sequence of events involving DNA in meiosis from chromosome

duplication through chromosome segregation. Explain how meiosis is different from mitosis.• Given an offspring’s genotype, predict the stage(s) of meiosis that could have been abnormal• Propose a testable hypotheses to explain observations

Active Learning Strategies• Interactive lecture, Think-pair-share, Story telling, Small and larger group discussion, Optional

drawing/labeling

Assessment Strategies• Interpretation of diagrams of meiosis, drawing chromosomes at different stages of meiosis, clicker-type

questions

Inclusive Teaching Strategies• Potential to engage many individuals since questions about reproduction are typically very interesting

to many people, story can relate to some religious perspectives

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AbstractThis lesson….

Introduction

When I was a graduate student, one of the staff in our department at Carnegie-Mellon University told me about her involvement in a women’s group that met annually in the woodlands of Pennsylvania to “frolic in nature.” My recollection of her description of this group suggested that an important topic of their conversation was how to eliminate the need for men in human society. I learned from her that a variety of vertebrates could produce babies without any involvement of sperm and, therefore, of males. She introduced me to the Beltsville White turkey breed, which produces unfertilized eggs that can hatch into little male turkeys that can go on to mate and produce viable offspring. I was fascinated with both the idea that an unfertilized egg could actually hatch to produce a viable baby bird (!) and that the baby bird would be male.

Fast forward about 10 years. I was teaching non-majors’ biology at the University of Washington and trying to interest my students in the stages of mitosis. After several abortive attempts spanning several years, I boiled it down to just metaphase and the products – if they could just line the chromosomes up at metaphase and identify the products of cell division, we’d call it a day.

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Why meiosis matters: The Case of the Fatherless Snake Robin Wright, University of Minnesota

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January 2014

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Jess Blum, Managing EditorRobin Wright, Editor in Chief

Sue Wick (University of Minnesota)Kathy Miller (Washington University, St. Louis)

Peter Bruns (HHMI), Malcolm Campbell (Davidson College), Erin Dolan (University of Georgia), Sarah Elgin (Washington University, St. Louis), Sarah Goodwin (ASCB, IBioSeminars),

Jo Handelsman (Yale University) and Bill Wood (University of Colorado, Boulder)