Robert Oates, M.D. - Cancer and Infertility

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Cancer is a devastating diagnosis but cure is so often achieved in this day and age that all of us need to pay great attention to preserving the fertility potential of every male patient, from infancy to adulthood. Sperm or testis tissue banking before any chemo or radiotherapy are options and require the most compassionate interaction with the patient and/or his parents and I am happy to provide that in as timely a fashion as humanly possible. Testis tissue harvesting after chemotherapy or radiation therapy might be necessary for some men and I have a tremendous amount of experience in this area, having published one of the first papers on the topic.

Transcript of Robert Oates, M.D. - Cancer and Infertility

Page 1: Robert Oates, M.D. -  Cancer and Infertility

Cancer and InfertilityRobert D Oates, M.D.

Boston Medical Center

Page 2: Robert Oates, M.D. -  Cancer and Infertility

Cancer in the maleTesticular cancer

Hodgkin’s disease

Lymphoma

Leukemia

Prostate

Various others

Cancer can strike at any time of life

Page 3: Robert Oates, M.D. -  Cancer and Infertility

Sperm bankingShould be offered to any male who can ejaculate

Prior to starting chemotherapy

chemotherapy will temporarily or permanently hurtsperm production

depends on the drugs used and how many cycles needed

Prior to starting radiation therapy

radiation therapy will temporarily or permanently hurtsperm production

depends on the location and dose

Page 4: Robert Oates, M.D. -  Cancer and Infertility

Sperm bankingI am happy to see a patient really quickly if banking is

necessary

Usually has to be done right away

I help the patient understand the process

I have all the materials for the sperm bank

After the banking is done, we speak on the phone

I help to review the numbers:

was one specimen enough ?

should there be a second one ?

I communicate with the referring Oncologist

Page 5: Robert Oates, M.D. -  Cancer and Infertility

Sperm banking: sometimes itwas not done !

Years later, there may be no sperm in the ejaculate

I was one of the first to describe TESE in these cases

We can often find sperm in the testicle itself (TESE)

This sperm works with ICSI

Fertilization

Embryo development

Pregnancy

Live birth

A possible option but every patient is different

Page 6: Robert Oates, M.D. -  Cancer and Infertility

TESE : is it an option ?

It may be depending upon the chemotherapy used

It may be depending on where the radiation was aimed

Should the TESE be done before an ICSI cycle and frozen ?

I was the first to apply this approach for patients

Should the TESE be done at the same time as an ICSI cycle ?

On occasion this is the best way to go

It takes a global knowledge of cancer to advise you properly

Page 7: Robert Oates, M.D. -  Cancer and Infertility

As one of the experts in this area, Iwould be happy to see you for an

appointment to discuss all that wemight have to in your particular case