RJPO Paediatric

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    Herlien H. Megawe Dept. of Anesthesiology & Reanimation

    Airlangga University School of MedicineSurabaya

    No matter what time it is, wake me up, even if its in the middle of a cabinet meeting

    Ronald Reagan

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    I. BASIC PRINCIPLES :

    a. Urgency of childs problem

    b. Ordering of priorities (e.g. epidural hematoma, closed femoral fracture)

    c. Critically ill and profound hypotensive condition, an immediate operationneeded resuscitation & anesthesia are provided simultaneously

    d. Establish : - clear airway : A- provide ventilation : B- support hemodynamics : C

    e. Hypnosis & analgesia, as condition will allow

    f. Titrated doses of : - Hypnotics (Benzodiazepine, for amnesia Ketamine)

    - Opioids for pain- Neuromuscular blocking agent for immobility

    g. As patient stabilizes, inhalation agent are added as tolerated

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    II. RAPID CLINICAL ASSESSMENT OF THE SERIOUSLY ILL INFANT/CHILD

    A = AIRWAY : - Obstruction

    - Partial- Total

    B = BREATHING : - Respiratory rate

    - Flare- Recession : - sternal- intercostal- subcostal

    - Silent chest C = CIRCULATION : - Pulse : volume

    - Blood pressure- Capillary refill time- EKG- Skin colour : - dry, red, warm

    - greyish, cold, wet, clammy

    D = DISABILITY : - Unresponsive to voice/pain- Posture- Pupils : size/reaction- Conscious level- Convulsions

    E = EXPOSSURE : - Rash - Purpura- Swelling - Urticaria

    - Fever - Angio-edema

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    ASSESSMENT OF PROGRESS AND DETECTION OF

    DETERIORATION :Re-assessment of ABCDE at frequent intervals

    LEVEL OF CONSCIOUSNESS SHOULD BE RECORDED USING

    THE AVPU SCALE : A : Alert V : Responds to voice

    * P : Responds to pain (GCS < 8)U : Unresponsive

    * Pinching a digit, pulling frontal hair

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    III. PATHWAYS LEADING TO CARDIO. RESPIRATORYARREST :

    FLUIDLOSS

    BLOOD LOSS

    GASTROENTERITIS

    BURN

    LOSSMALDISTRIBUTION

    SEPTIC SHOCK

    CARDIAC DISEASE

    ANAPHYLAXIS

    RESPIRATORYDISTRESS

    FOREIGN BODY

    CROUP

    ASTHMA

    RESPIRATORYDEPRESSION

    CONVULSIONS

    RAISED ICP

    POISONING

    CIRCULATORY

    FAILURE

    RESPIRATORY

    FAILURE

    CARDIAC ARREST

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    Indication for intubation and ventilation :

    Inadequate oxygenation via bag-and-mask technique

    Prolonged ventilation required

    Flail chest

    Inhalational burn injury

    Shock

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    VASCULAR ACCESSPreferred options :

    A. Intra venousB. Intra osseous

    A. Preferable via the superior v. cava Via the inferior v. cava takes longer to reach the heart Via the periph. route fluid flush

    First priority : accurate safety rapidlyB. Intra osseous :

    - Easy & safe- Reach the heart = periph. ven. access- Also in older age & adults

    C. Tracheal :Third placeFor first drug adrenaline

    D. Intracardiac : not recommended

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    IV. RESUSCITATION BEFORE ANESTHESIA

    Weight in kg = 2 (age in years + 4)

    Estimated blood volume = 80 ml/kg body weight

    Assess

    response

    Assessresponse

    F lu id vo lum e and typ e An initial fluid bolus of 20 ml/kg is given as fast

    as possible

    This should be repeated after assessment if thereis no improvement in vital signs

    The most common mistake in the treatment ofhypovolaemic shocked children is failure to giveenough fluid

    Crystalloid20 ml/kg

    Colloid20 ml/kg

    Blood

    UrgentSurgical opinion

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    V. OTHER VITAL PROCEDURES CARRIED OUT BEFORE

    RESUSCITATION AND ANESTHESIA : HISTORY :

    Vomit (quantity & quality) Last urination/defaecation) Bloody stool/profuse

    BLOOD TESTS (taken immediately after venous access)

    NASOGASTRIC TUBE PLACEMENT

    RADIOGRAPHS

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    VI. PLAN1. Weight (kg) = 2 (year + 4) kg2. Estimated Blood Volume : 80 ml/kg

    3. Internal diameter endotracheal tube : Year + 4 = one size smaller, actual size , one size bigger, e.g. :

    4 4 - 4,5 - 54. Fluid bolus : 20mg/kg

    - Crystalloid

    (Colloid)- Blood5. Defibrill. Dose I : 2 Joule/kg

    2 Joule/kg in 90 seconds4 Joule/kg

    Defibrill. Dose II : 4 Joule/kg4 Joule/kg in 90 seconds4 Joule/kg

    6. Between defibrill. dose I and II : Adrenalin dose I : 1 ml/10.000 sol. (10 Ug/kg) Adrenalin dose II : 1 ml/1000 sol. (100 Ug/kg)

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    VII. PREMEDICATION, ANXIETY & FEAR

    I.V. anticholinergics benefits :1. Maintenance of cardiac output by increasing heart rate2. Prevention of reflex bradycardia :

    Airway manipulation Scoline/halothane

    ANXIETY & FEAR

    Calm appearance Reassuring Of the anesthesiologist is of greatbenefit for patients & parents

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    VIII. URGENT SITUATION WITH COMPROMISED AIRWAY

    Foreign body aspiration Epiglottitis Croup Bleeding tonsil Facial/laryngeal trauma

    Compromised airway & struggle during intubation attempt,choices are : Awake intubation Volatile agent (Sevoflurane/Halothane) in oxygen with gentle

    cricoid pressureThis approach is favoured = The patient continues

    breathing ! Slight head down position : pulmonary aspiration is less likely

    when patient regurgigates

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    FULL STOMACH

    Postpone surgery for > 4 hours

    Reduce the mean gastric residual volume by 50% (does notguarantee empty)

    If there is no specific airway for difficult intubation Anesthesia of choice : rapid sequence of induction

    Pre-oxygenation + sulfas atropine Rapid induction agent : - Ketamine

    - Propofol- Thiopenthal

    Muscle relaxant = Recuronium 1,2 mg/kg The smaller the child, the more rapid he will desaturate (< FRC) Newborns can become hypoxic in less than 1 minute

    Difficult to pre-oxygenate & denitrogenate a struggling toddler

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    HYPOVOLEMIA

    Ongoing bloodloss

    Pending blood availability

    Type specific un-crossmatched low incidence oftransfusion reaction

    Ketamine : induction agent of choice in small

    dosis 1 2 mg/kg I.V. (within one minute) Atropine 0,02 mg/kg or scopolamine 0,01 mg/kg

    administered before

    5% Albumine

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    IX. PAIN MANAGEMENT

    Injured children are in pain on arrival Potentially hypovolemic : Fentanyl preferable

    Must be titrated in small increments (0,5 1,0 Ug/kg) to avoid

    chestwall or glottic rigidity

    Unstable & neurologic dysfunction : opioids with caution

    Regional nerve blocks = - femoral nerve

    - axillary

    Providing analgesia

    As a primary anesthetic

    (avoid risks of general anesth. = aspiration)

    Supplement for postop analgesia

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    CAUTIONS

    Titrate sedative in small increments to avoid lossof airway reflexes

    Appear alert & Sedation sleepy After the block : painfull stimuli is removed

    Close communication with surgeons = ability toperform sensory and motor examinations

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    X. SPECIAL PROBLEMS & MANAGEMENT A. AIRWAY

    Acute airway obstruction : Inspiratory stridor Tachypnoea Sternal & intercostal retractions Agitation (due to hypoxia) Cyanosis Tachycardia

    Few of these symptoms & signs are manifested, yet their

    condition may rapidly become life-threateningInitial respons :O2 & calm, to prevent dynamic collapse of the airway associated with agitation

    - Not cyanotic- Sable vital signs

    - Upright position- Supine position further airway obstruction

    Blood gas analysis is not vitalPaO2 = 80 torr ; orPaO2 = 60 torr

    In Contrast : pulse oxymetry Non-invasive Immediate & continuous means for assessing oxygenation

    Recommended as a modality in all airway emergencies

    X-ray is helpful clarifying the cause of obstruction

    does not alter the response of the anesthesiologist

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    B. UPPER AIRWAY OBSTRUCTION1. Epiglotitis Skill

    Knowledge Urgent diagnosis & treatment Additional signs : - drooling

    - difficulty in swallowing Favoured approach worldwide : Endotracheal intubation

    Avoid = inspection increase obstruction (dynamic airway collapse) Radiographic = - Only when stable- Skilled personnel- Adequate resuscitation equipment

    In the operationg room : Calm, sitting on the lap o/t mother Induction overface : - Halothane

    - Sevoflurane Looses consciousness supine Head up slightly

    Essential for the anesthesiologist

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    Intubation tehnique

    Lifting the base of the tongue

    Without touching the epiglottis

    Exposure of the rimaglottidis

    Partially obstructed orifice

    0,5 mm ID smaller choosen sprayed beforehand

    A stylet within the endotracheal tube Failure : - tracheostomy

    - cricothyorotomy

    Adequate sedation to prevent extubation

    * Titrated opioids

    - Breathe spontanneously

    - ETT remains in place for 24 48 hours, until swelling decreased

    - Extubation

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    2. Foreign body aspiration History of choking

    Cyanosis

    A wheezing child : Not always asthmatic May be foreign body aspiration

    Agitation : due to seriously underlying hypoxemia Radiographic examination

    If the child is stable Helpful to localize & identify Mostly are not radiopaque

    Hyperinflation Atelectasis Principle of anesthetic management = epiglottitis

    While eating suspicious

    (peanut, popcorn)

    Clues of presence of foreign body

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    C. LOWER AIRWAY OBSTRUCTION1. Bronchiolitis

    Tachypnea Retractions Wheezing Hyperinflated chest & diffuse crepitations Progressive exhaustion hypercarbia respiratory failure (silent chest)

    Focus of treatment = correct hypoxemia Pulse oxymetry : - degree of hypoxemia

    - respons to therapy Nebulized mist Bronchodilators

    Titrated I.V, fluids not able to drink Ribavirin : antiviral agentCaution : Particles tend to disk, obstructing the ventilator

    No absolute P aCO2 value that dictates the course of action

    Not proven beneficial

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    2. Asthma, status asthmaticus

    A cardinal feature : reversibility spontaneuous or with therapy Wheezing sinonymous with bronchospasm Predominant expir. wheezing With increasing fatique slight air movement wheezing no

    longer audible

    Management :a. Support oxygenationb. Reduce airway obstruction

    c. Support ventilationd. Prevent complication (e.g. pneumothorax)e. Inhaled & I.V. drugs

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    Anesthesia : Optimize oxygenation, control brochospasm Standard agents Ketamine : - Bronchodilating

    - Hypersecretion Avoid histamine release agents : - Morphine

    - Curare- Thiopental

    Drying of secretions intra-operatively : - Atropine- Glycopyrrolate

    May exacerbate mucous plugging post-operatively Wheezing during anesthesia mechanical problem :

    - endobronchial intubation- plugging, kinking- cuff herniation

    Mechanical ventilation is difficultHigh Airway Pressure: - air trapping

    - pneumomediastinum- pneumothorax

    Controlled mechanical ventilation: - Degree of hypercarbia is pernitted/accepted- Adequate oxygenation- Adequate cardiac output

    No sciencetific data yet

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    CIRCULATION :

    1. Hypovolemia : Most common cause of shock Crystalloid solutions are effective

    No scientific studies of superiority of colloid solutions Blood as soon as crossmatching is carried out, or

    O neg.Type spec. uncrossmatched

    Urgent

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    XI. OPERATING ROOM MANAGEMENT

    1. Acute blood loss Secure large bore venous access is of higher priority than arterial access Arterial catheters in :

    Arterial blood gas for adequate ventilationFrequent blood sampling : metabolic derangements

    Hemodynamic instabilityNeed to alter blood pressure rapidly

    Central venous access, only when hemodynamic stability returns Body temperature, hypothermia :

    Potentiates neuromuscular blockade

    Exacerbates coagulopathy

    2. Anesthesiologists vigilance continued : until care is transferred to the appropriate physicians and nurses

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