Rigolin - Case Studies - Morphology of Aortic Regurgitation ......Annulus: 2.5 x 3.3 cm Sinus of...
Transcript of Rigolin - Case Studies - Morphology of Aortic Regurgitation ......Annulus: 2.5 x 3.3 cm Sinus of...
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Case Studies: Morphology of Aortic Regurgitation, Root
Involvement
Vera H. Rigolin, MD, FASE, FACC, FAHAProfessor of Medicine, Northwestern University’s
Feinberg School of MedicineMedical Director, Echocardiography Laboratory
Northwestern Memorial HospitalPresident, American Society of Echocardiography
No Disclosures
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Introduction
• Aortic regurgitation may be caused by primary disease of the aortic valve leaflets and/or the wall of the aortic root.
• AR due to dilatation of the ascending aorta is now more common than primary valve disease in pts undergoing AVR for isolated AR.
AHA/ACC 2010 Guidelines for Thoracic Aortic Disease
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Gene Defects Associated with Familial Thoracic Aortic Aneurysm and Dissection
AHA/ACC 2010 Guidelines for Thoracic Aortic Disease
Genetic syndromes associated with thoracic aortic aneurysm and dissecxtion
AHA/ACC 2010 Guidelines for Thoracic Aortic Disease
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Risk factors for thoracic aortic dissection
AHA/ACC 2010 Guidelines for Thoracic Aortic Disease
Mechanisms of AR due to abnormalities of the ascending aorta
• Dilatation of the aortic annulus
– separation of the leaflets
– Tension and bowing of the leaflets result in thickening and retraction
• Aortic dissection
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Mechanisms of AR in Aortic Dissection
Feigenbaum’s Echocardiography, 7th ed. 2010
History
• 29 yr old female with Marfan’s syndrome
• Admitted with dyspnea and LE edema
• Diagnosed with an aortic aneurysm, chronic type A dissection and AR
• Presented to CT surgeon’s office with c/o chest pain
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History
• PMH: – Multiple sclerosis
– Asthma
– Scoliosis
– Dislocated lens
• FH– Mother with Marfan’s – died during aortic
surgery
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LVEDVI= 115 ml/m2LVESVI= 58 ml/m2
LVEF=50%
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Pressure halftime=239 msec
Prox desc Ao
Abdom Ao
CT of the aorta
Annulus: 2.5 x 3.3 cmSinus of Valsalva: 5.3 x 5.2 x 5.3 cmSino-tubular junction: 6 x 6 x 6.2 cmMid ascending aorta: 6.7 x 6.4 cmProximal aortic arch: 3.1 x 3.1 cmDistal aortic arch: 2.5 x 2.4 cmLower descending thoracic aorta: 1.8 x 1.7 cm
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Surgery
• Aortic root replacement with 27 mm Mechanical valve-graft
• Coronary reimplantation
• Resection and replacement of ascending aorta and total transverse arch using 24 mm dacrongraft with reimplantation of inominate artery
• Hypothermic circulatory arrest with antegradecerebral perfusion via right axillary artery cannulation
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History
• 65 yr old Asian female who presents to the ER with chest pain
• Patient does not speak English and relays her complaint by pointing to her chest and moaning
• Patient initially thought to have ACS
• Echo ordered when murmur was heard
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CT scan of the aorta
Stanford type A aortic dissection extending from the aortic valve to just beyond the origin of the left subclavian artery. The dissection also extends into the brachiocephalic artery.
Aneurysmal dilatation of the ascending aorta with a maximal dimension of 4.4 cm (non-orthogonal measurement).
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Surgery
• Replacement of aortic root and ascending aorta with a 32 mm Gelweave graft
• Repair of the aortic valve
History
• 35 yr old male with a known heart valve problem since childhood
• He presented with a febrile illness 8 months prior. Blood cx positive for Strep
• Successfully treated with antibiotics
• Now feels well
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MRA of the Aorta
There is aneurysmal dilatation of the mid ascending aorta.
The following orthogonal measurements of the thoracic aorta were obtained:Annulus: 3.2 by 3.3 cmSinus of Valsalva: 4.1 x 4.8 x 4.0 cm. The largest dimension is between the left coronary cusp and the non-coronary cusp. Sino-tubular junction: 4.1 x 3.9 cmMid ascending aorta: 5.0 x 5.1 cm Proximal aortic arch: 2.9 x 2.9 cmDistal aortic arch: 2.3 x 2.5 cmLower descending thoracic aorta: 2.1 x 2.2 cm
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Thank You