Dr Abdelaziz M. Hussein June 2018

Resume

Abdelaziz M. Hussein Assist Prof of Medical Physiology, Faculty of Medicine,

Mansoura University, Egypt

Secretary of Egyptian Society for Physiological Sciences

(ESPS)

Editorial Assistant of Bulletin of ESPS

Visiting Scientist, Department of Physiology and Biomedical

Engineering, Mayoclinic Rochester MN, USA, 2014

Member and General Secretary of IRB-Committee of

Mansoura Faculty of Medicine

Phone: Home: +2050/4994325

Mobile: (+201002421140)

Email :menhag@mans.edu.eg, zizomenna28@yahoo.com

Personal Informations

Nationality: Egyptian.

Date of Birth: December 28, 1972.

Place of Birth: Damas, MitGhamr, Dakahlia, Egypt.

Address: El-Amr Building, Masaken El-Shenaway, Mansoura, Egypt.

Religion: Muslim.

Marital Status: Married with 3 daughters

2

Major Capability: Postgraduate qualifications and have over 16 years experience in research along

with teaching and demonstration experience in different educational Institutes.

Hands on experience of induction of animal models of DM, Renal Ischemia, Adriamycin Nephropathy, Isoprenaline-induced Myocardial Infarction, PTZ-epileptic model, Cell Culture of human airway smooth muscles, Western Blotting, PCR, Confocal Microscopy, Immunocytochemistry, Isolation of cardiac myocytes and mitochondrial analysis by Matlab software

Medical Education, curriculum innovation and medical and paramedical Students assessments at both under- and postgraduate levels.

Creating E-courses for undergraduates students and online MCQ exams for postgraduates and undergraduate students

Special achievements: Research publications in international refereed journals and conference

proceedings.

Presentation of research findings at national and international scientific conferences.

Recipient of 9 research funds as co-investigator and principle investigator from STDF, Ministry of Higher Education

Education:

2008 PhD in Medical Physiology

Dissertation: Role of Epidermal Growth Factor and

Erythropoietin in Renal Ischemia/ Reperfusion Injury in

Rat Kidneys

Faculty of Medicine,

Mansoura University,

Egypt

2004 MSc in Medical Physiology (Good)

Dissertation: Role of L-arginine and Prostaglandin E1

in Renal Ischemia/ Reperfusion Injury in Rat Kidneys.

Faculty of Medicine,

Mansoura University

Egypt

1997 MBBCh (Very Good with Honor) Faculty of Medicine, Mansoura University, Egypt

3

Employment:

7-2014:7-2015 Assistant Prof of Medical Physiology

Department of Basic Medical Sciences, Faculty of Physical Therapy, Delta University, Egypt

4-2014: 7-2014 Visiting Scientist Department of Physiology and Biomedical Engineering, Mayoclinic Rochester MN, USA

11-2013:Till now Assistant Prof of Medical Physiology

Department of Medical Physiology, Faculty of Medicine, Mansoura University, Egypt

12-2012:2-2013 Visiting Professor of Medical Physiology

Department of Medical Physiology, Faculty of Medicine, Tripoli University, Libya

12-2008: 2-2009 Visiting Professor of Medical Physiology

Department of Medical Physiology, Faculty of Medicine, Alzwia University, Libya

8-2008 : 11-2013 Lecturer of Medical Physiology

Department of Medical Physiology, Faculty of Medicine, Mansoura University, Egypt

5-2004 : 8-2008 Assistant Lecturer of Medical Physiology

Department of Medical Physiology, Faculty of Medicine, Mansoura University, Egypt

6-1999:5-2004 Demonstrator of Medical Physiology

Department of Medical Physiology, Faculty of Medicine, Mansoura University, Egypt

3-1999: 6-1999 Primary health care physician

Mansoura health district, Dakahlia Health Directorate, MOHP, Egypt

3-1998: 2-1999 Rotating internship Mansoura University Hospital, Egypt

Administrative Positions:

1. Head of Research Projects and Prizes Committee, Mansoura Faculty of

Medicine, Mansoura University, Egypt from June 2013 –June 2014

2. Head of the committee of online MCQ exams for postgraduate students ,

Mansoura Faculty of Medicine, Mansoura University, Egypt from June 2015-June

2016

3. Member and Secretary of IRB unit-Mansoura Faculty of Medicine, Mansoura

University, Egypt from Jan 2017 till now

4

Teaching Activities:

1. Teaching Practical courses of Medical Physiology for medical undergraduate

students from 1999 till now

2. Teaching theoretical parts of Medical Physiology of Nerve and Muscle,

Biophysics and Cardiovascular System, Pulmonary System, Digestive

System, Central Nervous System, Special Senses, Metabolism, Endocrine

and Renal Physiology for medical undergraduate students from 2008 till now

3. Teaching courses of Medical Physiology for the undergraduate students of

Nursing, Dentistry and Pharmacy and Public Health Institute from 2008 till

now

4. Teaching courses of medical physiology for the undergraduate students of

Physical Therapy from 2013 till now

5. Author of E-course of Physiology of Special Senses funded by national E-

learning Center (NELC) (ICTP and SCU), Egypt.

http://mansvu.mans.edu.eg/site/index.php?page=ecourse&task=show&lang=ar.

http://www.tubey.net/viewFauyIUMbnWg.html

6. Teaching for undergraduate students of Manchester Mansoura Medical

Program (MMMP) (problem based learning program) and tutor in Semesters

1, 2, 4 and 5 of the program for more than 7 years.

7. Sharing in putting exams for students of MMMP (written, MCQ and OSCE)

8. Teaching Courses of Applied Physiology for Neurology, Rheumatology and

Hematology Master Postgraduate Students from 2013 till now.

Books:

1. Sharing in Staff-Member Textbook of Medical Physiology for Undergraduate Medical Students

2. Author of Basic Medical Physiology Textbook for Students of Nursing Faculty and Health Institute

3. Author of Medical Physiology Textbook for Students of Physical Therapy Faculty, Delta University

4. Author of Book of Physiology of Special Senses

5

Training Courses:

1. English Language course, Mansoura Faculty of Medicine, 2001.

2. Program for preparing the university teaching staff, Mansoura Faculty of

Education, 2001.

3. Medical Statistics course, Mansoura Faculty of Medicine, 2007.

4. Scientific & Research Methodology course, Mansoura Faculty of Medicine, 2007.

5. 6 FLDP workshops (2008) entitled;

a. Financial and law regulations of university (15 hours)

b. Effective presentation skills course (15 hours)

c. Teaching with technology (15 hours)

d. Effective teaching (15 hours)

e. Decision making & problems solving (15 hours)

f. Career ethics & rules (15 hours)

6. 6 FLDP workshops (2009- 2013) entitled;

a. Financial and legal aspects of university (15 hours)

b. Standards of educational process (15 hours)

c. Credit hour system (15 hours)

d. National and international competing Research projects (15 hours)

e. Research project management (15 hours)

f. Examination assessment and evaluation (15 hours)

7. 4 FLDP workshops (2013- 2018) entitled;

a. Conference management (15 hours)

b. Research design (15 hours)

c. Creation of online exams (15 hours)

d. Methods of statistical analysis (15 hours)

e. Reference management (15 hours)

f. Internet web scientific search engines (15 hours)

6

Workshops:

1. Workshop titled “Basic Techniques in Tissue Culture” organized by the

Research Medical Center, Alexandria Faculty of Medicine, 2008.

2. Workshop titled “Trends and Challenges in Physiology Education: Africa and

the West 6th international congress of African association of physiological

science, Ismailia, Egypt, Sept, 2, 2012.

3. Workshop titled “Basics of Molecular Biology, Mansoura, Egypt, Sept, 12-18,

2012.

4. Coordinator and speaker in the 1st international Workshop in “Basics of

Molecular Biology, Urology and Nephrology Center, Mansoura, Egypt, Sept,

21-27, 2013.

5. Coordinator of the Workshop entitled “Getting Started in Animal Behavior”

Mansoura, Egypt, Jan, 13, 2016.

6. Coordinator of the Workshop entitled “Experimental uses of biopac system”

Mansoura, Egypt, Dec, 27, 2017.

7. Coordinator of the Workshop entitled “Deep brain stimulation and stereotaxic

targeting in rats” Mansoura, Egypt, Dec, 28, 2017 done by Prof. Osama

Abulseoud (Prof of Neuropsychiatry, NIH, USA)

Research grants:

1. Co-investigator in research project in Urology and Nephrology center,

Mansoura University entitled "Recoverability of renal function after relief of

chronic unilateral ureteric obstruction in solitary kidney". This work was

funded by the Science and Technology Development Fund (STDF), Egypt-grant

no. 996., 2009

2. Co-investigator in research project in Urology and Nephrology center,

Mansoura University entitled "chromosomal instability and bladder cancer".

This project was funded through the Science and Technology Development Fund

(STDF), Egypt-grant no. 1080.2010

7

3. Co-investigator in research project in Urology and Nephrology center,

Mansoura University entitled "Renal protection against renal

ischemia/reperfusion injury". This project was funded by the Science and

Technology Development Fund (STDF), Egypt-grant no. 1146, 2011.

4. Co-investigator in research project in Urology and Nephrology center,

Mansoura University entitled "stem cell and acute kidney injury". This project

was funded by the Science and Technology Development Fund (STDF). Egypt-

grant no. 3948,2012

5. Supervisor of student's research project in Mansoura experimental research

center (MERC) entitled "pancreatic injury in renal ischemia/reperfusion

injury: possible role of oxidative stress". This project was funded by MERC,

Mansoura University, 2012

6. Supervisor of student's research project in Mansoura experimental research

center (MERC) entitled "hepatic injury induced by ischemia/reperfusion

injury: role of nitric oxide". This project was funded by MERC, Mansoura

University, 2012

7. Co-investigator in project of accreditation of molecular biology laboratory in

urology and nephrology center. This work is funded by Ministry of Higher

Education, Egypt, 2013

8. Co-investigator in project of Excellence Center in urology and nephrology

center. This work is funded by Ministry of Higher Education, Egypt. 2014

9. Supervisor of student's research project in Mansoura experimental research

center (MERC) entitled "Role of Toll Like receptors (TLRS) in Remote Limb

ischemic effect on renal ischemia/reperfusion Injury." This project was

funded by MERC, Mansoura University, 2014.

10. Supervisor of student's research project in Mansoura experimental research

center (MERC) entitled "Role of renin-angiotensin system in Remote Limb

ischemic effect on renal ischemia/reperfusion Injury". This project was

funded by MERC, Mansoura University, 2014

11. Visiting Scientist In Department of Physiology and Biomedical Engineering,

Mayoclinic Rochester MN, USA, April 14, 2014- June 14, 2014.

8

12. PI investigator for research project The effect of the muscular exercise and

ferulic acid on neuroprotective heat shock proteins in experimental

Parkinson’s model. This project was funded by STDF Egypt, grant NO.6896,

2015.

Publications

Google scholar site :

https://scholar.google.com.eg/citations?user=EhtNaqMAAAAJ&hl=en

Scopus

https://www.scopus.com/authid/detail.uri?authorId=56590274900

Research gate

https://www.researchgate.net/profile/Abdelaziz_Hussein

1) International peer-reviewed journals:

1. Isameel Bin-Jaliah, Abdelaziz M. Hussein, Hussein F Sakr, Elsayed A. Eid. Effects of

Low Dose of Aliskiren on Isoproterenol –Induced Acute Myocardial Infarction in

Rats. Accepted in International Physiology Journal. 2018 2. Hussein F Sakr, Abdelaziz M. Hussein, Elsayed Eid, Mahmoud Elkhateeb. Possible

Mechanisms Underlying Fatty Liver in a Rat Model of Male Hypogonadism: A

Protective Role for Testosterone. Steroids 2018, 35: 21-30.

3. Mai Barakat, Mahmoud Gabr, Faten Zhran, Mohamed El Adel, Abdelaziz M.

Hussein, Nashwa Barakat, Reda Eldemerdash. Upregulation of Heme Oxygenase

(HO)-1 attenuates Kidney Damage, Oxidative stress and Inflammatory Reaction

during Renal Ischemia/Reperfusion Injury. Gen Physiol Biophys. 2018, 37(2):193-

204.

4. Hussein AM, Adel M, El-Mesery M, Abbas KM, Ali AN, Abulseoud OA. l-Carnitine

Modulates Epileptic Seizures in Pentylenetetrazole-Kindled Rats via Suppression of

Apoptosis and Autophagy and Upregulation of Hsp70. Brain Sciences. 2018;8(3):45.

9

5. AM El-Wakf, ESM El-Habibi, NM Barakat, AM Attia, AM Hussein. Cardiovascular

Toxic Effects of Chlorpyrifos: A Possible Protective Role for Pomegranate Extracts. J

Clin Toxicol, 2018; 8 (374): 2161-0495.1000374

6. Abdelaziz M. Hussein, Khaled M. Abbas, Osama A Abulseoud, El-Hussainy M.A.

El-Hussainy. Effects of Ferulic Acid on Oxidative Stress, Heat Shock Protein 70,

Connexin 43 and Monoamines in Hippocampus of Pentylenetetrazole-Kindled Rats.

Can J Physiol Pharmacol. 2017; 95(6):732-742.

7. Abdelaziz M. Hussein, Nisreen M Aboelmaaty and Eman W Abd Allah, Emile F

Metias. Modulation of ECG, Myocardial Oxidative Stress markers and Connexin 43

Expression by Ascorbic acid and Ferulic Acid in Isoproterenol-Induced Myocardial

Infarction in Rats. Biochem Physiol 2016, 5:4. DOI: 10.4172/2168-9652.1000210

8. Abdelaziz M. Hussein, Hussein F Sakr, Faris Q. Alenzi. Possible Underlying

Mechanisms of The Renoprotective Effect of Remote Limb Ischemic Preconditioning

Against Renal Ischemia/Reperfusion Injury: A Role of Osteopontin, TGF-beta and

Survivin. Nephron Physiol, 2016; 134(2): 117-129

9. Hussein AM, Ghalwash M, Magdy K, Abulseoud OA. Beta Lactams Antibiotic

Ceftriaxone Modulates Seizures, Oxidative Stress and Connexin 43 Expression in

Hippocampus of Pentylenetetrazole Kindled Rats. J Epilepsy Res. 2016 30;6(1):8-15.

10. Amani M.D. El-Mousalamy, Abdelaziz M. Hussein, Seham A. Mahmoud, Azza

Abdelaziz, Gehan Shaker. Aqueous and Methanolic Extracts of Palm Date Seed and

Fruit Flesh (Phoenix Dactylifera) Protects Against Diabetic Nephropathy in Type II

Diabetic Rats. Biochem Physiol 2016, 5:2. http://dx.doi.org/10.4172/2168-

9652.1000205

11. Abdelaziz M. Hussein, Nashwa Barakat, Amira Awadalla, Mahmoud M. Gabr,

Sherry Khater, Ahmed Harraz, Ahmed A. Shokeir. Modulation of Renal

Ischemia/Reperfusion in Rats by A Combination Ischemic Preconditioning and

Adipose-Derived Mesenchymal Stem Cells (ADMSCs). Canad. J. Physiol. Pharmacol.

2016; 94 (9): 936-946

10

12. El-Hussainy M.A. El-Hussainy, Abdelaziz M. Hussein, Azza Abdelaziz, Ibrahim El-

Mehasseb. Effects of Aluminum oxide (Al2O3) Nanoparticles on ECG, Myocardial

Inflammatory Cytokines, Redox State and Connexin 43 and Lipid Profile in Rats:

Possible Cardioprotective Effect of Gallic Acid. Canad. J. Physiol. Pharmacol. 2016;

94 (8): 868-878

13. Abdelaziz M. Hussein, Hala Abdel Malek and Mohamed Ahdy Saad. Renoprotective

Effects Aliskiren on Adenine-induced Tubulointerstitial Nephropathy: Possible

Underlying Mechanisms. Canad. J. Physiol. Pharmacol. 2016; 94 (8): 829- 837

14. Abdelaziz M. Hussein, Mohamed El-dosoky, Ahmed Handle, Mohammed E. Sarhan,

Hanaa G. El-Serougy, Mohammed A. Sobh, Mahmoud Elhussiny, Eman El Nashar.

Effects of alpha darbopeiotin on Adriamycin-Induced Chronic Nephropathy. Int Urol

Nephrol (2016) 48:287–297

15. Ahmed A. Shokeir, Nashwa Barakat, Abdelaziz M. Hussein, Amira Awadalla,

Ahmed Harraz, Shery Khater, Kamel Hemmaid. Remote limb ischemic

preconditioning (rIPC) activates antioxidant and antiapoptotic genes and inhibit

proinflammatory cytokine genes in renal ischemia/reperfusion injury. Gen. Physiol.

Biophys. (2016), 35, 77–86

16. Hassan Abol-Enein, Abdelrhaman N. Zekri, Abdel-aziz M. Hussein, Amira Awadalla,

Amira ALHawari, Sherry Khater, Kamel Z. Hemmaid, Mai Bakr, Ahmed A. Shokeir.

Molecular Profiling of Early Stage Bilharzial Bladder Cancer in Egypt by cDNA

Microarray. Inter J of Cancer Research, 2015,article in press.

17. Mohamed Zahran, Nashwa Barakat, Abdelaziz M. Hussein, Amira Awadalla, Ahmed

Harraz, Shery Khater, Ahmed A. Shokeir. Sildenafil activates antioxidant and

antiapoptotic genes and inhibits proinflammatory cytokine genes in a rat model of

renal ischemia/reperfusion injury. Int J Urol Nehrol 2015, 47(11): 1907-1915

18. Ahmed A. Shokeir, Nashwa Barakat, Abdelaziz M. Hussein, Amira Awadalla,

Ahmed Harraz, Shery Khater, Kamel Hemmaid. Activation of Nrf2 by Ischemic

Preconditioning and Sulforaphane in Renal Ischemia/Reperfusion Injury: A

Comparative Experimental Study. Physiol Res. 2015;64(3):313-23.

11

19. Abdelaziz M Hussein, Amani MD El-Mousalamy, Sahar AM Hussein, Seham A

Mahmoud. Effects of Palm Dates (Phoenix Dactylifera L) Extracts on Hepatic

Dysfunctions in Type 2 Diabetic Rat Model. World J Pharmacy and Pharmaceutical

Sciences. 4(7): 62-79: 2015

20. Ahmed A. Shokeir Amira Awadalla, Hassan Aboelenin, Kamel Zaki Hemmaid,

Abdelaziz M. Hussein, Essam Elsawy, Rania A. Nada , Azza Abdelaziz. Pattern of

DNA Hypermethylation of APC, P16, P73, P16, O6MMGT, CD99 and CDH1 Genes

in Bladder Cancer with Hepatitis C Viral (HCV) Infection. Inter J of Cancer Research,

2015,49(1): 1690-1703

21. Kamel Zaki Hemmaid, Amira Awadalla, Hassan Aboelenin, Abdelaziz M. Hussein,

Essam Elsawy, Mai B Mohammed, Abd El-Rahman, Nabawy Zekri Microsatellite

Chromosomal Instability in Bladder Cancer Patients Infected with Hepatitis C Virus.

IJSR – inter J Scientific Research, 2014; 3(9): 2277 - 8179

22. Sakr HF1, Khalil KI, Hussein AM, Zaki MS, Eid RA, Alkhateeb M. Effect of

Dehydroepiandrosterone (DHEA) on Memory and Brain derived neurotrophic factor

(BDNF) in a Rat Model of Vascular Dementia. J Physiol Pharmacol. 2014 Feb;

65(1):41-53.

23. Mohammed E. Sarhan, Hanaa G. El-Serougy, Abdelaziz M. Hussein, Mohamed El-

dosoky, Mohammed A. Sobh, Fatma Elhusseini. Impact of Bone Marrow-Derived

Mesenchymal Stem Cells on Adriamycin-Induced Chronic Nephropathy. Can J

Physiol Pharmacol. 2014 Sep;92(9):733-43. doi: 10.1139/cjpp-2013-0503. Epub 2014

Apr 8

24. Abd El-Aziz M Hussein, Mohamed O Seisa, Hazem K Khaled, , Mie M Ali , Amel A

Ezzat, Azza Baiomy, Hussein A Sheashaa, Mohamed A Sobh. Hepatic injury induced

by ischemia/reperfusion role: role of nitric oxide. General physiology and biophysics.

2014;33(2):205-13. doi: 10.4149/gpb_2013084.

25. Abd El-Aziz M. Hussein, Aya Abd-Elkhabir, Amany Abozahra, Azza Baiomy, Sylvia

A. Ashamallah, Hussein A. Sheashaa, Mohamed A. Sobh. Pancreatic Injury Secondary

12

to Renal Ischemia/Reperfusion (I/R) Injury: Possible Role of Oxidative Stress. Physiol

Res. 2014;63(1):47-55. Epub 2013 Nov 1.

26. Ahmed A. Shokeir, Abdelaziz M. Hussein, Amira Awadallah, Azza Abdelaziz,

Nashwa Barakat. Activation of Nrf2 gene and its dependent genes by ischemic

preconditioning and post-conditioning. Acta Physiol (Oxf). 2014; 210(2): 342-353

27. Sahar Abd Elaziz ELdakroory, Hala Abdel Malek, Abdel-Aziz M. Hussein and Amira

Kamal Elhawary. Evaluation of Doxorubicin Toxicity; Does Ferulic Acid have a

Possible Protective Effect like Ginkgobiloba? Mansoura Journal of Forensic Medicine

and Clinical Toxicology, Jan, 2013.

28. Samy Eleawa, Hussein F. Sakr, Abdelaziz M. Hussein, Abdullah .S. Assiri, Mahmoud

Alkhateeb, Nervana M. K. Bayoumy. Effect of Testosterone Replacement Therapy on

Cardiac Performance and Oxidative Stress in Orchidecotomized Rats. Acta Physiol

(Oxf). 2013 Oct;209(2):136-47. doi: 10.1111/apha.12158.

29. Kamel Z Hemmaid, Amira Awadalla, Essam Elsawy, Abdel-aziz M Hussein, Azza

Abdel-aziz, Ahmed A Shokeir, Ahmed S El-Hefnawy, and Hassan Abol-enein. Impact

of Hepatitis C Virus (HCV) infection on biomolecular markers influencing the

pathogenesis of bladder cancer. Infect Agent Cancer. 2013 Jun 28;8(1):24. doi:

10.1186/1750-9378-8-24.

30. Ahmed A. Shokeir, Abdelaziz M. Hussein, Amira Awadallah, Ahmed Samy, Azza

Abdelaziz, Sheiri Khater , Nashwa Barakat. Protection against Renal Ischemia/

Reperfusion Injury: A Comparative Experimental Study of the impact of Ischemic

Preconditioning versus Post-conditioning. Arab J of Urology 10 (4): 418-424, 2012.

31. Abdelaziz M. Hussein, Nashwa Barakat, Amira Awadalla, Ahmed A. Shokeir.

Systemic and Renal Haemodynamic Changes in Renal Ischemia/Reperfusion Injury:

Impact of Erythropoietin. Can J Physiol Pharmacol. 2012 Nov;90(11):1535-43. doi:

10.1139/y2012-120. Epub 2012 Nov 8.

32. Mohamed S.H. and Hussein A M.. Altered secretory activity in rat adrenal chromaffin

cells after experimentally induced bronchial asthma and dexamethasone treatment:

13

ultrastructural and biochemical study. The Egyptian Journal of Histology: 2012; 35

(1): 117–126

33. Omar NM, Hussein AM, Malek HA, Saad MA, Saleh DM. Influence of Age on Pain

Sensitivity in Response to Paw Pressure and Formalin Injection in Rats: A Role of

Nitric Oxide. Gen Physiol Biophys. 2012; 31(2):185-94.

34. Hussein AA M., Abbas AM, El Wakil GA, Elsamanoudy AZ, El Aziz AA. Effect of

chronic excess iodine intake on thyroid function and oxidative stress in hypothyroid

rats. Can J Physiol Pharmacol. 2012 May;90(5):617-25. doi: 10.1139/y2012-046. Epub

2012 May 2.

35. Hussein AA, Abdel-Aziz A, Gabr M, Hemmaid KZ. Myocardial and metabolic

dysfunction in type 2 diabetic rats: impact of ghrelin. Can J Physiol Pharmacol. 2012

Jan;90(1):99-111. doi: 10.1139/y11-103. Epub 2011 Dec 21.

36. Hussein AA, El-Dken ZH, Barakat N, Abol-Enein H. Renal ischaemia/reperfusion

injury: possible role of aquaporins. Review article. Acta Physiol (Oxf). 2012

Mar;204(3):308-16. doi: 10.1111/j.1748-1716.2011.02372.x. Epub 2011 Nov 5.

37. Shokeir AA, Hussein AA, Soliman SA, Kamal MM, Abdel-Aziz A, Awadalla A,

Rahim MA, Barakat N. Recoverability of Renal Functions after Relief of Partial

Ureteral Obstruction of Solitary Kidney: Impact of Ferulic Acid. BJU Int. 2012

Sep;110(6):904-11. doi: 10.1111/j.1464-410X.2011.10848.x. Epub 2012 Mar 1.

38. Shokeir AA, Barakat N, Hussein AA, Awadalla A, Abdel-Aziz A, Abo-Elenin H.

Role of combination of L-arginine and α- tocopherol in renal transplantation

ischaemia/ reperfusion injury: a randomized controlled experimental study in a rat

model. BJU Int. 2011 Aug;108(4):612-8. doi: 10.1111/j.1464-410X.2010.09943.x.

Epub 2011 May 18

39. Hussein Ael-A, Omar NM, Sakr H, Elsamanoudy AZ, Shaheen D. Modulation of

Metabolic & Cardiac Dysfunctions by Insulin Sensitizers and Angiotensin Receptor

Blocker in Rat Model of Type 2 Diabetes Mellitus. Can J Physiol Pharmacol. 2011

Mar;89(3):216-26. doi: 10.1139/Y11-012.

14

40. Mahmoud Gabr, Abdel-aziz Hussein, Iman Sherif, Sousou Ali & Hoda Mohamed.

Renal ischemia /reperfusion injury in type II DM: Possible role of proinflammatory

cytokines, apoptosis, and nitric oxide. Journal of Physiology and Pathophysiology

2011; 2(1): 6-17.

41. Hussein Ael-A, Shokeir AA, Sarhan ME, El-Menabawy FR, Abd-Elmoneim HA, El-

Nashar EM, Barakat NM Effects of combined erythropoietin and epidermal growth

factor on renal ischaemia/reperfusion injury: a randomized experimental controlled

study. BJU Int. 2011 Jan;107(2):323-8. doi: 10.1111/j.1464-410X.2010.09328.x.

42. Barakat N, Hussein AA, Abdel-Maboud M, El-Shair MA, Mostafa A, Abol-Enein H.

Ischemia/Reperfusion Injury in Renal Transplantation: The Role of Nitric Oxide in

Experimental Rat Model. BJU Int. 2010 Oct;106(8):1230-6. doi: 10.1111/j.1464-

410X.2010.09225.x.

43. Mahmoud IM, Hussein A.A., Sarhan ME, Awad AA, El Desoky I. Role of Combined

L-Arginine and Prostaglandin E 1 in Renal Ischemia-Reperfusion Injury. Nephron

Physiol. 2007;105(4):p57-65. Epub 2007 Mar 1.

2) Abstracts in international conferences

1. Mahmoud Gabr, Abdel-aziz Hussein, Iman Sherif, Sousou Ali & Hoda Mohamed.

Renal ischemia /reperfusion injury in type II DM: Possible role of

proinflammatory cytokines, apoptosis, and nitric oxide. Endocrine Abstracts

(2011) 25 P121. Society for Endocrinology BES 2011

2. Shokeir AA, Hussein AA, Soliman SA, Kamal MM, Abdel-Aziz A, Awadalla A, Rahim

MA, Barakat N. Recoverability of Renal Functions after Relief of Partial Ureteral

Obstruction of Solitary Kidney: Impact of Ferulic Acid. 9th congress of EUA ,

Insbruk, Austria, sept 2011

3. Abdelaziz Husssein, Aya abdelkhabir et al., pancreatic injury in renal

ischemia/reperfusion injury : possible role of oxidative stress accepted as poster

15

in 1st American Diabetes Association Middle East Congress in Dubai, 4-6 Dec.

2012

4. Shokeir AA, Hussein AA, Abdel-Aziz A, Awadalla A, Barakat N. Activation of

Nuclear factor (erythroid 2-like)-Related Factor 2 (Nrf2) and Nrf-2 dependent

genes by ischemic preconditioning and postconditioning: New Adaptive

Endogenous Protective Responses against Renal Ischemia/Reperfusion Injury.

American Urological Association, USA, 2013

5. Mohamed O Seisa, Hazem K Khaled, Abd El-Aziz M Hussein, Mie M Ali , Amel A

Ezzat, Azza Baiomy, Hussein A Sheashaa, Mohamed A Sobh. Hepatic injury

induced by ischemia/reperfusion role : role of nitric oxide, accepted as poster in

continuous renal replacement therapy (CRRT) conference USA, 2013

6. Mohamed Zahran, Abdelaziz M. Hussein, Ahmed Harraz, Amira Awadalla, Shery

Khater, Nashwa Barakat, Ahmed Shokeir. Sildenafil activates nrf2 dependent

antioxidant genes aand apoptotic Bcl2 genes and inhibits proinflammatory

cytokine genes in rat model of renal ischemia/reperfusion injury.MP70.10. AUA

conference, Saint Deigo, USA, 2015/4/30

7. Abdelaziz M. Hussein, Nisreen M Aboelmaaty and Eman W Abd Allah, Emile F

Metias. Effects of ascorbic acid and ferulic acid on ECG, myocardial oxidative

stress and connexin 43 expression in isoproterenol-induced myocardial

infarction in rats. 6th International Conference on Clinical & Experimental

Cardiology, USA, 2015/2/12.

8. Khaled Magdy, Abdelaziz M. Hussein, Osama Abulseoud. Role of Oxidative

Stress, Neuroprotective Heat Shock Protein 70 and Connexin 43 in

Pentylenetetrazole-induced Seizures in Rats: Possible Protective Effect of Ferulic

Acid.12th European Congress on Epileptology, Prague, Czech Republic from

Sept 11 to 15, 2016.

9. Khaled Magdy, Abdelaziz M. Hussein, Mohamed Ghalwash. Beta Lactams

Antibiotic Ceftriaxone Modulates Seizures, Oxidative Stress and Connexin 43

(Cx43) Expression in Hippocampus of Pentylenetetrazole Kindled Rats. 8th

Neurology Congress, Amsterdam, Netherlands, 21-23 Sept 2016

16

10. Khaled Magdy, Abdelaziz M. Hussein, Osama Abulseoud. Role of Oxidative

Stress, Neuroprotective Heat Shock Protein 70 and Connexin 43 in

Pentylenetetrazole-induced Seizures in Rats: Possible Protective Effect of Ferulic

Acid. 4th Middle East Epilepsy Congress, ILAE, Luxor, Egypt from Feb 15 to

18, 2017.

3) National Journals Publications

1. Hussein F. Sakr, Abdelaziz M. Hussein, Khaled I. Khalil and Amr M. Abbas. Effect

of Testosterone on the Cerebral Cortex Bcl-2 Expression and Oxidative Stress in a

Rat Model of Vascular Dementia. Bull Egy Soc Physiol Sci, 34, 88-103, 2014.

2. Abdelaziz Hussein. Hepatic injury secondary to renal ischemia/reperfusion

injury: possible role of nitric oxide. Benha Medical J Jan 2013, Vol 30.

3. Hussein AA, Abdel-Aziz A, Awadalla A, Barakat N. Combined Effect of angiotensin

receptor blocker, and antioxidants on Recoverability of Renal Functions after

Relief of Partial Ureteral Obstruction of Solitary Kidney. Benha Medical Journal.

2012; 27(1): 193-215.

4. Kamel Z Hemmaid, Amira Awadalla, Essam Elsawy, Abdel-aziz M Hussein, Azza

Abdel-aziz, and Hassan Abol-enein. The Impact of HCV infection on Telomerase

and Retinoblastoma Genes Expression In bladder Cancer. Benha Medical Journal.

2010; 27(3): 193-215.

5. Amr Abass, Abdelaziz Hussein, Gehan Elwakeel. Effect of Long Term Excessive

Iodine Intake on Thyroid Functions and Oxidative Stress in Euthyroid and

Hypothyroid Rats. Bulletin Egyptian Society of Physiological Sciences, 2010:

30(2): 65-85.

6. Mahmoud Gabr, Ayman Elrefee, Abdelaziz Hussein. The Role of Nitric Oxide in

Metabolic Dysfunctions and Oxidative Stress in Type 1 Diabetes Mellitus: An

experimental Rodent Study. Benha Medical Journal. 2010; 27(1): 87-98.

Conferences:

a) National Conferences:

17

1. Attending and participate in the Annual Scientific Conference of Mansoura faculty

of Medicine titled; Quality and Institutional Accreditation, Mansoura, Egypt, 6th

November, 2010.

2. Attending and participate in the 2nd scientific annual conference of MERC,

Mansoura faculty of Medicine titled; Nanotechnology and Stem cells

transplantation in regenerative medicine (Liver, Kidney and Heart).Mansoura,

Egypt, 28-29 Sept, 2010.

3. Attending the 1st scientific annual conference of MERC, Mansoura faculty of

Medicine titled; stem cells and regenerative medicine. Mansoura, Egypt, 8th April,

2010.

4. Attending and Speaker in all scientific annual conferences of Physiology

Department (7 conferences), Mansoura faculty of Medicine from 2007 to 2013.

Mansoura, Egypt

5. Attending the Annual Scientific Congress of Mansoura faculty of Medicine titled:

New Trends in Medical Education and Evaluation. Mansoura, Egypt, 2006.

6. Attending the conference of Mansoura faculty of Medicine with special reference

to the annual scientific conference titled Quality Assurance in Scientific Research.

Mansoura and Alexandria, Egypt, 17-19 March, 2004

b) International Conferences:

1. Organizer and general secretary of the 8th annual scientific conference of

physiology department, Mansoura Faculty of medicine, Updates in Neurosciences,

Dec 2017

2. Khaled Magdy, Abdelaziz M. Hussein, Mohamed Ghalwash. Beta Lactams

Antibiotic Ceftriaxone Modulates Seizures, Oxidative Stress and Connexin 43

(Cx43) Expression in Hippocampus of Pentylenetetrazole Kindled Rats. 8th

Neurology Congress, Amsterdam, Netherlands, 21-23 Sept 2016

3. Khaled Magdy, Abdelaziz M. Hussein, Osama Abulseoud. Role of Oxidative

Stress, Neuroprotective Heat Shock Protein 70 and Connexin 43 in

Pentylenetetrazole-induced Seizures in Rats: Possible Protective Effect of Ferulic

18

Acid.12th European Congress on Epileptology, Prague, Czech Republic from

September 11 to 15, 2016.

4. Abdelaziz M. Hussein, Nisreen M Aboelmaaty and Eman W Abd Allah, Emile F

Metias. Effects of ascorbic acid and ferulic acid on ECG, myocardial oxidative

stress and connexin 43 expression in isoproterenol-induced myocardial

infarction in rats. 6th International Conference on Clinical & Experimental

Cardiology, USA, 2015/2/12.

5. Mohamed Zahran, Abdelaziz M. Hussein, Ahmed Harraz, Amira Awadalla, Shery

Khater, Nashwa Barakat, Ahmed Shokeir. Sildenafil activates nrf2 dependent

antioxidant genes aand apoptotic Bcl2 genes and inhibits proinflammatory

cytokine genes in rat model of renal ischemia/reperfusion injury.MP70.10. AUA

conference, Saint Deigo, USA, 2015/4/30

6. Attending and speaker in the 7th scientific annual conference of Egyptian society

for Physiological Sciences (ESPS). Alex, Alex Library, Egypt, March, 2015.

7. Attending and speaker in the 32nd scientific annual conference of Egyptian society

of nephrology and transplantation (ESNT). Alex, Alex Library, Egypt, 5 – 8 March,

2014.

8. Attending and speaker in the 1st Biomedical Sciences Conference. Ismailia, Faculty

of Medicine, Egypt, Oct, 2015.

9. Organizer and coordinator of the 7th annual scientific conference of physiology

department, Stress and Immunity, Mar 2013

10. Attending and speaker in the 31st scientific annual conference of Egyptian society

of nephrology and transplantation (ESNT). Cairo, Citystar, Egypt, 12 – 15 Feb,

2013.

11. Attending and actively participate in the 3rd international congress of MERC

entitled regenerative medicine, Mansoura and Alexandria, Egypt, Nov, 27-30,

2012.

12. Attending and poster presentation in the 6th international congress of African

Association of Physiological Sciences (AAPPS), Ismailia, Egypt, Sept, 3-5, 2012.

13. Attending and poster presentation in the 9th world congress of urological

research, Innsbruck, Austria, Sept, 15-17, 2011.

19

Thesis Supervision:

1. Role of renin angiotensin system in sympathetic remodeling in Diabetic

cardiomyopathy in type 2 DM in rats. Youmna Yehia, Master degree in Medical

Physiology 2017

2. Effects of extracts of Stavia on Skeletal muscle performance in Type 1 Diabetic

Rats. Seham Ahmed, PhD degree in Science, 2016

3. Effect of Heme Oxygenase (HO)-1 Induction On ECG, Heat Shock Protein 70

(Hsp70) And Connexin 43 (CX 43) In Isoproterenol-induced Myocardial

Infarction in Rats. Somia Ahmed, Master degree in Medical Physiology 2016

4. Effects of different extraction of palm date seeds and fruits (phoenix dactylifera)

on diabetic nephropathy: An experimental Biochemical study. Seham Ahmed,

Master degree in Science, 2014

5. Effect of muscular exercise and ferulic acid on cardiac arrhythmia Isoprenaline-

induced myocardial infarction. Eman Wagih .Master degree in medical

Physiology, 2013.

6. Effect of muscular exercise and ferulic acid on neuroprotective heat shock

proteins in experimental Parkinson model. Mona Hamdy. PhD in medical

Physiology, 2013.

7. Adult Neurogenesis and Neural Plasticity: Application to Memory. Sara El-

Farash. An Essay for Master Degree in Physiology. 2012.

8. Effect of Erythropoietin and Endothelial Progenitor Cells on Neovascularization in

Animal Model of Chronic Nephropathy. Thesis for PhD degree in physiology.

Mohammed El-Desouky Mohammed Salama. 2013.

9. Physiology of aquaporins. An Essay thesis for master degree in physiology.

Zeinab Helmey Hussein El-Dken. 2009.

Thesis Reviewing

20

1. Chemical study of palm dates (phoenix Dactylifera L) fruits Extracts and

evaluation of its biological activities. Seham Ahmed, Faculty of Science,

University of Zagazig, 2015

1. Effect of Orbitrak training on Upper Limb Muscle Strength and Range of Motion in

Postrenal transplantation. Aya Ashraf. Faculty of Physical Therapy, 2015.

2. Adult Neurogenesis and Neural Plasticity: Application to Memory. Sara El-

Farash. Faculty of Medicine, Mansoura University, An Essay for Master Degree in

Physiology. 2012.

Reviewer in:

1. Journal of Cardiovascular Diabetologica

2. Canadian Journal of Physiology and Pharmacology

3. Malaysian Medical Journal

4. African Journal of Pharmacy and Pharmacology

5. King Abdul-Aziz city for science and technology, Riyadh, KSA

6. Journal of Urology

7. Experimental Diabetes Research Journal

8. Physiological research journal

9. Food & Function journal (Royal Society of Chemistry)

Membership:

1. Egyptian Medical Syndicate from 1999 till now.

2. Egyptian Society of Physiological Sciences

3. American Society of Physiology from 2009 till now.

21

Prizes and Awards:

Year Name of Award Awarding Institute

2009 Best PhD thesis Mansoura University 2012 University Encouragement Award Mansoura University 2014 Best article Published in international journal Misr ElKheir Organization 2016 State Prize of Hassan Hamidy Prize In Physiology Academy of Scientific Research 2017 State Encouragement Award In Medical Sciences Academy of Scientific Research

References

1. Gary Sieck (PhD), Department of Physiology and Biomedical Engineering, Mayo

clinic, Rochester, MNS, USA.

200 First Street SW

Mayo Clinic in Minnesota, Rochester, MN U.S.A. 55905

Email:sieck.gary@mayo.edu

Phone Number: 507-255-8488

2. Ahmed Shokeir (MD, PhD), Director of Mansoura Urology and Nephrology

center, Mansoura, Egypt

72 Gomhoria Street, Urology and Nephrology, Mansoura-Egypt

Tel: +20 (50) 2262222

Mobile: +201121102929

Ahmed.shokeir@hotmail.com

3. Hassan Abol-Enein (MD), Mansoura Urology and Nephrology center, Mansoura,

Egypt Urology and Nephrology Center,

72 Gomhoria Street, Urology and Nephrology, Mansoura- Egypt

Tel: 002050 2262222

Mobile: +201110611754

e-mail: hassanabolenein@hotmail.com