RESPIRATORY VIRUS SURVEILLANCE REPORT · Division of Public Health Respiratory Virus Surveillance...

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RESPIRATORY VIRUS SURVEILLANCE REPORT Wisconsin Department of Health Services | Division of Public Health Bureau of Communicable Diseases | Communicable Diseases Epidemiology Secon www.dhs.wisconsin.gov/dph/bcd.htm | [email protected] Week 14, Ending April 4, 2020 P-02346

Transcript of RESPIRATORY VIRUS SURVEILLANCE REPORT · Division of Public Health Respiratory Virus Surveillance...

Page 1: RESPIRATORY VIRUS SURVEILLANCE REPORT · Division of Public Health Respiratory Virus Surveillance Report Week 14: Ending April 4, 2020 Influenza vaccine composition 2019-2020: The

RESPIRATORY VIRUS SURVEILLANCE REPORT

Wisconsin Department of Health Services | Division of Public Health

Bureau of Communicable Diseases | Communicable Diseases Epidemiology Section

www.dhs.wisconsin.gov/dph/bcd.htm | [email protected]

Week 14, Ending April 4, 2020

P-02346

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Division of Public Health Respiratory Virus Surveillance Report Week 14: Ending April 4, 2020

STATE OF WISCONSIN REGION V OF US

(WI, MN, IL, MI, OH, IN)

UNITED STATES

ILI: BELOW BASELINE ILI: HIGH LEVELS ILI: MODERATE LEVELS

INFLUENZA-ASSOCIATED

PEDIATRIC DEATHS REPORTED:

INFLUENZA LIKE ILLNESS (ILI) ACTIVITY

For National US influenza surveillance statistics visit: www.cdc.gov/flu/weekly/

Week 14, 2020

October 1, 2019 to present

Wisconsin 0 3

Nationwide 4 166

ILI: INSUFFICIENT DATA

AT-A-GLANCE:

Predominant Viruses of the Week: Rhino/enterovirus and COVID-19 were the predominant viruses this week.

Current Alerts:

The percentage of deaths attributed to pneumonia and influenza (P&I) increased for the fifth consecutive week. P&I last week was 10.3%, far exceeding the state threshold of 6.8%.

P&I percentage nationally also exceeds threshold levels.

Based on the low incidence of influenza statewide and nationally, the increase in P&I deaths is likely due to COVD-19..

Additional data on COVID-19 in Wisconsin can be found at

https://www.dhs.wisconsin.gov/covid-19/data.htm

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Division of Public Health Respiratory Virus Surveillance Report Week 14: Ending April 4, 2020

Influenza and Pneumonia Deaths, Wisconsin

INFLUENZA AND PNEUMONIA-ASSOCIATED MORTALITY

Influenza- and pneumonia-associated deaths by influenza season year and week, Wisconsin

Influenza season week

Influenza-

associated

deaths (I)

Pneumonia-

associated

deaths (P)

Percent I+P of

all deaths

Baseline I+P

of all deaths

Threshold I+P

of all deaths

12 19 92 8.3% 6.0% 6.8%

13 13 93 8.5% 6.0% 6.8%

14

Preliminary Data 7 99 10.3% 6.0% 6.8%

Seasonal total 167 2005 5.6% NA NA

Data source: DPH, Office of Health Informatics

Influenza- and pneumonia-associated deaths by most recent influenza season week,

Wisconsin, 2019-2020 season

3%

4%

5%

6%

7%

8%

9%

10%

11%

201

6-4

0

201

7-0

2

201

7-1

6

201

7-3

0

201

7-4

4

201

8-0

6

201

8-2

0

201

8-3

4

201

8-4

8

201

9-1

0

201

9-2

4

201

9-3

8

201

9-5

2

202

0-1

4

Percent of deaths associated with

influenza and pneumonia

Influenza season year-week

Percent of deaths associated with influenza and pneumonia Baseline Threshold

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Division of Public Health Respiratory Virus Surveillance Report Week 14: Ending April 4, 2020

Wisconsin positive influenza results and subtypes by PCR

Cumulative number of positive influenza PCR tests by subtype September 1, 2019 to present

WISCONSIN LABORATORY SURVEILLANCE

FOR RESPIRATORY VIRUSES BY PCR

0%

9%

18%

27%

36%

45%

0

900

1,800

2,700

3,600

4,500

8/24 9/21 10/19 11/16 12/14 1/11 2/8 3/7 4/4 5/2

% P

osi

tive

by

PC

R

Nu

mb

er o

f po

siti

ve d

ete

ctio

ns

Week ending

A (unknown subtype) A (H3N2 seasonal) A (H1N1) A (H3N2v)

B (unknown subtype) B (Victoria) B (Yamagata) Influenza % positive

57% 43%

A (2009 H1N1) A (H3N2) A (Unknown) B (Victoria) B (Yamagata) B (Unknown)

Total positive (n) 1003 168 19587 618 10 14770 36156

% of total positive 3% 0% 54% 2% 0% 41% 100%

Influenza A: Influenza B:Total

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Division of Public Health Respiratory Virus Surveillance Report Week 14: Ending April 4, 2020

Trends in respiratory virus activity by PCR

WISCONSIN LABORATORY SURVEILLANCE FOR

RESPIRATORY VIRUSES BY PCR

Respiratory virus Tested Positive

(n)

Positive

(%)

Influenza A Influenza B

H3N2 2009 H1N1 Unknown Victoria Yamagata Unknown

Influenza 3937 38 1.0% 0 4 17 0 0 17

Respiratory virus Tested

Positive

(n)

Positive

(%) Parainfluenza 1 Parainfluenza 2 Parainfluenza 3 Parainfluenza 4

Parainfluenza 1079 1 0.1% 0 0 1 0

Respiratory virus Tested Positive

(n)

Positive

(%) CoV 229E CoV OC43 CoV NL63 CoV HKU1

Coronavirus 60 2 3.3% 0 0 2 0

Respiratory virus Tested Positive (n) Positive (%)

RSV 2176 42 1.9%

Human metapneumovirus 1086 25 2.3%

Rhino-enterovirus 997 65 6.5%

Adenovirus 60 1 1.7%

Week 14: Ending on April 4, 2020

0%

10%

20%

30%

40%

50%

1/18 1/25 2/1 2/8 2/15 2/22 2/29 3/7 3/14 3/21 3/28 4/4

% P

osi

tive

by

PC

R (3

-we

ek

mo

vin

g av

era

ge)

Week ending

― Influenza― RSV― hMPV- - Rhino-Entero― Adenovirus- - Parainfluenza- - Coronavirus

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WISCONSIN STATE SUMMARY

ILI activity trend analysis

Influenza and RSV trend analysis

Influenza rapid antigen tests RSV rapid antigen tests Influenza-like illness (ILI)

Tested Positive (n)

% Positive Tested Positive (n) % Positive ILI % Baseline Threshold Influenza A Influenza B Total

717 7 4 11 1.5% 54 7 13.0% 3.5% 2.4% 3.6%

0%

1%

2%

3%

4%

5%

6%

7%

9/1 9/22 10/13 11/3 11/24 12/15 1/5 1/26 2/16 3/8 3/29 4/19 5/10 5/31

Ave

rage

% I

LI

Week ending

Baseline Threshold 3-week moving average (average % ILI)

0%

8%

16%

24%

32%

40%

9/1 9/22 10/13 11/3 11/24 12/15 1/5 1/26 2/16 3/8 3/29 4/19 5/10 5/31

% P

osi

tive

by

an

tige

n d

etec

tio

n

Week ending

3-week moving average (RSV) 3-week moving average (Influenza)

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WISCONSIN STATE SUMMARY

ILI activity trend analysis by influenza season, Wisconsin

Influenza-associated hospitalizations, Wisconsin Electronic Disease Surveillance System

September 1, 2019 to present

Reported cumulative influenza-associated hospitalizations by influenza season, Wisconsin

A (2009

H1N1)

A

(H3N2)

A

(Unknown)B

Not

reported

<1 87 5 0 35 26 21 12 4

1-4 205 6 0 63 68 68 29 9

5-17 313 4 0 64 98 147 28 11

18-49 881 51 2 423 189 216 124 41 71 13

50-64 1108 95 6 774 134 99 185 53

65+ 1848 166 20 1292 272 98 246 58

Total 4442 327 28 2651 787 649 624 176 71 13

Postpartum

(≤6 weeks)

Age group

(years)

Total

reported

(n)

Influenza subtypeAdmitted

to ICU

Required

mechanical

ventilation

Pregnant

0

1000

2000

3000

4000

5000

6000

7000

4 5 6 7 8 9 10 11 12 13 14

Influ

enza

-ass

ocia

ted

hosp

ital

izat

ions

, cu

mul

ativ

e (n

)

Influenza season week

2015-2016

2016-2017

2017-2018

2018-2019

2019-2020

0%

1%

2%

3%

4%

5%

6%

40 42 44 46 48 50 52 2 4 6 8 10 12 14 16 18 20

Ave

rage

% I

LI (3

-wee

k m

ovi

ng

ave

rage

)

Influenza season week

― 2015-16- - 2016-17- - 2017-18― 2018-19― 2019-20

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Division of Public Health Respiratory Virus Surveillance Report Week 14: Ending April 4, 2020

NORTHEASTERN REGION

ILI activity trend analysis

Influenza and RSV trend analysis

Influenza rapid antigen tests RSV rapid antigen tests Influenza-like illness (ILI)

Tested Positive (n)

% Positive Tested Positive (n) % Positive ILI % Baseline Threshold Influenza A Influenza B Total

196 3 1 4 2.0% 24 4 16.7% 2.4% 2.6% 4.0%

0%

1%

2%

3%

4%

5%

6%

7%

9/1 9/22 10/13 11/3 11/24 12/15 1/5 1/26 2/16 3/8 3/29 4/19 5/10 5/31

Ave

rage

% I

LI

Week ending

Baseline Threshold 3-week moving average (average % ILI)

0%

8%

16%

24%

32%

40%

9/1 9/22 10/13 11/3 11/24 12/15 1/5 1/26 2/16 3/8 3/29 4/19 5/10 5/31

% P

osi

tive

by

an

tige

n d

etec

tio

n

Week ending

3-week moving average (RSV) 3-week moving average (Influenza)

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Division of Public Health Respiratory Virus Surveillance Report Week 14: Ending April 4, 2020

NORTHWESTERN REGION

ILI activity trend analysis

Influenza and RSV trend analysis

Influenza rapid antigen tests RSV rapid antigen tests Influenza-like illness (ILI)

Tested Positive (n)

% Positive Tested Positive (n) % Positive ILI % Baseline Threshold Influenza A Influenza B Total

160 3 1 4 2.5% 26 3 11.5% 2.1% 1.9% 3.2%

0%

1%

2%

3%

4%

5%

6%

7%

9/1 9/22 10/13 11/3 11/24 12/15 1/5 1/26 2/16 3/8 3/29 4/19 5/10 5/31

Ave

rage

% I

LI

Week ending

Baseline Threshold 3-week moving average (average % ILI)

0%

8%

16%

24%

32%

40%

9/1 9/22 10/13 11/3 11/24 12/15 1/5 1/26 2/16 3/8 3/29 4/19 5/10 5/31

% P

osi

tive

by

an

tige

n d

etec

tio

n

Week ending

3-week moving average (RSV) 3-week moving average (Influenza)

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Division of Public Health Respiratory Virus Surveillance Report Week 14: Ending April 4, 2020

SOUTHEASTERN REGION

ILI activity trend analysis

Influenza and RSV trend analysis

Influenza rapid antigen tests RSV rapid antigen tests Influenza-like illness (ILI)

Tested Positive (n)

% Positive Tested Positive (n) % Positive ILI % Baseline Threshold Influenza A Influenza B Total

342 1 2 3 0.9% 3 0 0.0% 4.0% 2.9% 4.1%

0%

1%

2%

3%

4%

5%

6%

7%

9/1 9/22 10/13 11/3 11/24 12/15 1/5 1/26 2/16 3/8 3/29 4/19 5/10 5/31

Ave

rage

% I

LI

Week ending

Baseline Threshold 3-week moving average (average % ILI)

0%

8%

16%

24%

32%

40%

9/1 9/22 10/13 11/3 11/24 12/15 1/5 1/26 2/16 3/8 3/29 4/19 5/10 5/31

% P

osi

tive

by

an

tige

n d

etec

tio

n

Week ending

3-week moving average (RSV) 3-week moving average (Influenza)

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Division of Public Health Respiratory Virus Surveillance Report Week 14: Ending April 4, 2020

SOUTHERN REGION

ILI activity trend analysis

Influenza and RSV trend analysis

Influenza rapid antigen tests RSV rapid antigen tests Influenza-like illness (ILI)

Tested Positive (n)

% Positive Tested Positive (n) % Positive ILI % Baseline Threshold Influenza A Influenza B Total

35 2 2 4 11.4% 8 0 0.0% 5.2% 2.1% 3.2%

0%

1%

2%

3%

4%

5%

6%

7%

9/1 9/22 10/13 11/3 11/24 12/15 1/5 1/26 2/16 3/8 3/29 4/19 5/10 5/31

Ave

rage

% I

LI

Week ending

Baseline Threshold 3-week moving average (average % ILI)

0%

5%

10%

15%

20%

25%

30%

35%

40%

45%

50%

9/1 9/22 10/13 11/3 11/24 12/15 1/5 1/26 2/16 3/8 3/29 4/19 5/10 5/31

% P

osi

tive

by

an

tige

n d

etec

tio

n

Week ending

3-week moving average (RSV) 3-week moving average (Influenza)

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Division of Public Health Respiratory Virus Surveillance Report Week 14: Ending April 4, 2020

Influenza vaccine composition 2019-2020:

The trivalent vaccines for use in the 2019-2020 influenza season contain the following:

A/Brisbane/02/2018 (H1N1)pdm09–like virus (updated)

A/Kansas/14/2017 (H3N2)-like virus (updated) B/Colorado/06/2017-like (Victoria lineage) virus

It is recommended that quadrivalent vaccines containing two influenza B viruses contain the above three viruses and:

B/Phuket/3073/2013-like virus (Yamagata lineage)

Cumulative percentage of Wisconsin residents who received 1 or more doses of

influenza vaccine, 2019-2020 influenza season

SEASONAL INFLUENZA VACCINATION

Data source: All influenza vaccination rates presented were calculated using data from the Wisconsin

Immunization Registry (numerator) and Wisconsin population estimates (denominator).

42%

40%

70%

0% 50% 100%

This season so far

2018-19 Total Vaccinated

Healthy People 2020 GoalHealthy People 2020 Goal

2018-2019Total Vaccinated

2019-2020 as of 03/19/2020

As of 02/01/2020, the cumulative percent of Wisconsin residents vaccinated has surpassed the total from the 2018-2019 season.

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Division of Public Health Respiratory Virus Surveillance Report Week 14: Ending April 4, 2020

SEASONAL INFLUENZA VACCINATION

Percentage of Wisconsin residents who received one or more doses of influenza

vaccine, by age group and influenza season

Each season includes doses administered during the same time period (August 1 through May 3).

Percentage of Wisconsin residents who received one or more doses of influenza

vaccine, by race and ethnicity and region, 2019-2020 influenza season

Southeastern Western Southern

27%

32%

26%

38%

30%

39%

42%Total

Non-Hispanic

Hispanic

White

Black

Asian

American Indian/

Alaska-Native

All of Wisconsin Northeastern Northern

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

0 years 1 to 4 years 5 to 17 years 18 to 49 years 50 to 64 years 65 years plus All Ages

2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 as of current week

33%

31%

25%

40%

30%

41%

43%

27%

32%

21%

38%

26%

40%

41%

22%

32%

22%

39%

29%

40%

41%

34%

34%

24%

36%

30%

37%

46%

15%

32%

26%

37%

29%

39%

40%